scholarly article | Q13442814 |
P2093 | author name string | H Zheng | |
E H Koo | |||
L H Van der Ploeg | |||
R G Perez | |||
P2860 | cites work | Processing of beta-amyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion | Q67766420 |
Amyloid precursor protein metabolism in primary cell cultures of neurons, astrocytes, and microglia | Q71082198 | ||
Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells | Q71971007 | ||
Cell-surface beta-amyloid precursor protein stimulates neurite outgrowth of hippocampal neurons in an isoform-dependent manner | Q72632596 | ||
The amyloid precursor protein is developmentally regulated and correlated with synaptogenesis | Q72787226 | ||
Amyloid precursor protein in cortical neurons: coexistence of two pools differentially distributed in axons and dendrites and association with cytoskeleton | Q72816597 | ||
Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides | Q22242269 | ||
Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension | Q28513050 | ||
Embryonic expression pattern of amyloid protein precursor suggests a role in differentiation of specific subsets of neurons | Q28592569 | ||
beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity | Q28593175 | ||
The establishment of polarity by hippocampal neurons in culture | Q29616334 | ||
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor | Q29618322 | ||
Expression of the class III beta-tubulin isotype in developing neurons in culture. | Q30434068 | ||
Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice | Q33893148 | ||
Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitro | Q36235391 | ||
Amyloid beta-protein as a substrate interacts with extracellular matrix to promote neurite outgrowth | Q36317817 | ||
Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons | Q36382469 | ||
Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact | Q36416236 | ||
Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides | Q36596465 | ||
Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch components | Q36831631 | ||
Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage | Q37239146 | ||
Growth of a rat neuroblastoma cell line in serum-free supplemented medium | Q37313160 | ||
A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth | Q38309410 | ||
Alzheimer's disease: a central role for amyloid | Q40701623 | ||
Mechanisms of neuronal degeneration in Alzheimer's disease | Q40986730 | ||
Neural cell adhesion molecules in activity-dependent development and synaptic plasticity | Q41226225 | ||
Interaction of beta-amyloid peptides with integrins in a human nerve cell line | Q41380136 | ||
Role of amyloid precursor protein (APP): study with antisense transfection of human neuroblastoma cells | Q41630684 | ||
Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion | Q41709571 | ||
The regulation of amyloid beta protein precursor secretion and its modulatory role in cell adhesion | Q41760569 | ||
Integrins in point contacts mediate cell spreading: factors that regulate integrin accumulation in point contacts vs. focal contacts | Q41953774 | ||
Ligand-dependent G protein coupling function of amyloid transmembrane precursor | Q42066774 | ||
Amyloid beta protein enhances the survival of hippocampal neurons in vitro | Q44109304 | ||
Secreted form of amyloid beta protein precursor is involved in the growth regulation of fibroblasts. | Q45966280 | ||
Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury | Q48092228 | ||
The survival of rat cerebral cortical neurons in the presence of trophic APP peptides | Q48129570 | ||
Secreted forms of beta-amyloid precursor protein modulate dendrite outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neurons | Q48151610 | ||
Intraneuronal compartments of the amyloid precursor protein. | Q48258074 | ||
Functional organization of microtubule-associated protein tau. Identification of regions which affect microtubule growth, nucleation, and bundle formation in vitro | Q48332155 | ||
Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein | Q48342880 | ||
The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth | Q48458288 | ||
MAP2 is localized to the dendrites of hippocampal neurons which develop in culture | Q48685423 | ||
GGF/neuregulin is a neuronal signal that promotes the proliferation and survival and inhibits the differentiation of oligodendrocyte progenitors | Q48956089 | ||
Modulation of the PC12 cell response to nerve growth factor by antisense oligonucleotide to amyloid precursor protein. | Q53201006 | ||
P433 | issue | 24 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Alzheimer's disease | Q11081 |
Amyloid beta (A4) precursor protein | Q14865884 | ||
P304 | page(s) | 9407-9414 | |
P577 | publication date | 1997-12-01 | |
P1433 | published in | Journal of Neuroscience | Q1709864 |
P1476 | title | The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity | |
P478 | volume | 17 |
Q28565029 | A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference |
Q39739662 | A macromolecular complex involving the amyloid precursor protein (APP) and the cytosolic adapter FE65 is a negative regulator of axon branching |
Q36078010 | A role for the beta-amyloid precursor protein in memory? |
Q34083364 | A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression |
Q36674481 | A two decade contribution of molecular cell biology to the centennial of Alzheimer's disease: are we progressing toward therapy? |
Q35052570 | APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP. |
Q34551487 | APP as a Protective Factor in Acute Neuronal Insults |
Q22251088 | APP binds DR6 to trigger axon pruning and neuron death via distinct caspases |
Q42689739 | APP independent and dependent effects on neurite outgrowth are modulated by the receptor associated protein (RAP). |
Q48449860 | Activation of calpain in cultured neurons overexpressing Alzheimer amyloid precursor protein |
Q43906174 | Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome |
Q34142269 | Alzheimer's disease as a disorder of mechanisms underlying structural brain self-organization |
Q34105788 | Alzheimer's disease: a dysfunction of the amyloid precursor protein(1). |
Q52575657 | Amyloid Precursor Protein Dimerisation Reduces Neurite Outgrowth. |
Q53234381 | Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease. |
Q38767379 | Amyloid precursor like protein-1 promotes JNK-mediated cell migration in Drosophila |
Q34208401 | Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer's disease |
Q37427458 | Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors |
Q30492443 | Amyloid precursor protein increases cortical neuron size in transgenic mice |
Q36928448 | Amyloid precursor proteins interact with the heterotrimeric G protein Go in the control of neuronal migration |
Q27012950 | Amyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's disease |
Q43850189 | Amyloid-associated neuron loss and gliogenesis in the neocortex of amyloid precursor protein transgenic mice. |
Q52720530 | BACE1 Mediates HIV-Associated and Excitotoxic Neuronal Damage Through an APP-Dependent Mechanism. |
Q47368687 | Beta secretase activity in peripheral nerve regeneration |
Q35098524 | Beta-amyloid and cholinergic neurons |
Q44848075 | Beta-secretase-cleaved amyloid precursor protein in Alzheimer brain: a morphologic study. |
Q37217951 | Biochemistry and molecular biology of amyloid beta-protein and the mechanism of Alzheimer's disease |
Q37869935 | Biology and pathophysiology of the amyloid precursor protein |
Q35934211 | Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases |
Q36739538 | Changes in the structural complexity of the aged brain |
Q34286933 | Closing in on the amyloid cascade: recent insights into the cell biology of Alzheimer's disease |
Q33622388 | Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-KO mice that is prevented by APPsα expression |
Q28344424 | Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-alpha converting enzyme |
Q28504488 | Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members |
Q34331096 | Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: a magnetic resonance microscopy and stereologic analysis |
Q64947642 | Differential expression of beta-amyloid precursor and Bcl-2 proto-oncogene proteins in the developing dog retina. |
Q35924071 | Divide and die: cell cycle events as triggers of nerve cell death. |
Q40643184 | Downregulation and increased turnover of beta-amyloid precursor protein in skeletal muscle cultures by neuregulin-1. |
Q40922286 | Effect of HIV-1 gp41 peptides on secretion of beta-amyloid precursor protein in human astroglial cell line, T98G. |
Q48243692 | Enriched early experiences of mice underexpressing the beta-amyloid precursor protein restore spatial learning capabilities but not normal openfield behavior of adult animals |
Q73453669 | Expressions of amyloid precursor protein, synaptophysin and presenilin-1 in the different areas of the developing cerebellum of rat |
Q28567859 | FE65 interacts with ADP-ribosylation factor 6 to promote neurite outgrowth |
Q34240652 | Factors controlling axonal and dendritic arbors |
Q28282518 | Fe65 and the protein network centered around the cytosolic domain of the Alzheimer's beta-amyloid precursor protein |
Q37935600 | Functions of the APP gene family in the nervous system: insights from mouse models |
Q91635058 | Hebbian and Homeostatic Synaptic Plasticity-Do Alterations of One Reflect Enhancement of the Other? |
Q34439668 | Hox genes and their candidate downstream targets in the developing central nervous system |
Q47812408 | Increased production of amyloid precursor protein provides a substrate for caspase-3 in dying motoneurons. |
Q24655186 | Interaction of reelin with amyloid precursor protein promotes neurite outgrowth |
Q35747757 | Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology |
Q51731926 | Knockout of Amyloid β Protein Precursor (APP) Expression Alters Synaptogenesis, Neurite Branching and Axonal Morphology of Hippocampal Neurons. |
Q28592893 | Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein |
Q42495065 | Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. |
Q82954939 | Neurofibromin and amyloid precursor protein expression in dopamine D3 receptor knock-out mice brains |
Q99711299 | New Insights Into Blood-Brain Barrier Maintenance: The Homeostatic Role of β-Amyloid Precursor Protein in Cerebral Vasculature |
Q28587148 | No hippocampal neuron or synaptic bouton loss in learning-impaired aged beta-amyloid precursor protein-null mice |
Q39209681 | Not just amyloid: physiological functions of the amyloid precursor protein family |
Q36595737 | Novel GαS-protein signaling associated with membrane-tethered amyloid precursor protein intracellular domain. |
Q28593653 | Pancortins interact with amyloid precursor protein and modulate cortical cell migration |
Q48496690 | Phosphorylation of actin-depolymerizing factor/cofilin by LIM-kinase mediates amyloid beta-induced degeneration: a potential mechanism of neuronal dystrophy in Alzheimer's disease. |
Q37987144 | Physiological functions of APP family proteins |
Q34995120 | Presenilins and APP in neuritic and synaptic plasticity: implications for the pathogenesis of Alzheimer's disease |
Q21245229 | Pro-inflammatory interleukin-18 increases Alzheimer's disease-associated amyloid-β production in human neuron-like cells |
Q53818447 | Receptors of intermediates of carbohydrate metabolism, GPR91 and GPR99, mediate axon growth. |
Q51987758 | Recombinant human amyloid precursor-like protein 2 (APLP2) expressed in the yeast Pichia pastoris can stimulate neurite outgrowth. |
Q35827478 | Reduced BACE1 activity enhances clearance of myelin debris and regeneration of axons in the injured peripheral nervous system |
Q48354682 | Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome |
Q47593384 | Regulation of Neurotransmitter Release by Amyloid Precursor Protein Through Synapsin Phosphorylation |
Q24633831 | Relationships between expression of apolipoprotein E and beta-amyloid precursor protein are altered in proximity to Alzheimer beta-amyloid plaques: potential explanations from cell culture studies |
Q38929253 | Restoring Soluble Amyloid Precursor Protein α Functions as a Potential Treatment for Alzheimer's Disease. |
Q28202553 | Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory |
Q37956562 | Roles of amyloid precursor protein family members in neuroprotection, stress signaling and aging |
Q36740945 | Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1. |
Q33988005 | Secreted human amyloid precursor protein binds semaphorin 3a and prevents semaphorin-induced growth cone collapse. |
Q51767122 | Selective interaction of amyloid precursor protein with different isoforms of neural cell adhesion molecule. |
Q39537635 | Soluble amyloid precursor protein induces rapid neural differentiation of human embryonic stem cells. |
Q40340003 | Suppression of cyclin-dependent kinase 5 activation by amyloid precursor protein: a novel excitoprotective mechanism involving modulation of tau phosphorylation. |
Q47710423 | Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress. |
Q37258141 | Systematic evaluation of candidate ligands regulating ectodomain shedding of amyloid precursor protein |
Q37634348 | The Age of Cortical Neural Networks Affects Their Interactions with Magnetic Nanoparticles |
Q36293844 | The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement |
Q41170054 | The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance. |
Q26750116 | The Neuroprotective Properties of the Amyloid Precursor Protein Following Traumatic Brain Injury |
Q38843876 | The Proteasome and Oxidative Stress in Alzheimer's Disease |
Q28254943 | The Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's Disease |
Q24306930 | The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo |
Q24680465 | The amyloid precursor protein: beyond amyloid |
Q28584739 | The coxsackievirus-adenovirus receptor protein as a cell adhesion molecule in the developing mouse brain |
Q26799258 | The endocrine dyscrasia that accompanies menopause and andropause induces aberrant cell cycle signaling that triggers re-entry of post-mitotic neurons into the cell cycle, neurodysfunction, neurodegeneration and cognitive disease |
Q33799169 | The evolution of aging-related brain change |
Q34079605 | The genetics and molecular pathology of Alzheimer's disease: roles of amyloid and the presenilins |
Q33821071 | The insect homologue of the amyloid precursor protein interacts with the heterotrimeric G protein Go alpha in an identified population of migratory neurons |
Q36113757 | The keystone of Alzheimer pathogenesis might be sought in Aβ physiology |
Q33264215 | The modular systems biology approach to investigate the control of apoptosis in Alzheimer's disease neurodegeneration |
Q39686458 | The neurodegeneration mutant löchrig interferes with cholesterol homeostasis and Appl processing |
Q37825632 | The upside of APP at synapses |
Q47073605 | The zebrafish amyloid precursor protein-b is required for motor neuron guidance and synapse formation |
Q33588638 | Transgenic animals relevant to Alzheimer's disease |
Q43284371 | Transgenic expression of human wild-type amyloid precursor protein decreases neurogenesis in the adult hippocampus |
Q33678168 | Translating cell biology into therapeutic advances in Alzheimer's disease |
Q37515518 | Understanding the molecular basis of Alzheimer's disease using a Caenorhabditis elegans model system |
Q36256183 | Unique responses of differentiating neuronal growth cones to inhibitory cues presented by oligodendrocytes |
Q53254496 | Upregulation and antiapoptotic role of endogenous Alzheimer amyloid precursor protein in dorsal root ganglion neurons. |
Q33838961 | What the evolution of the amyloid protein precursor supergene family tells us about its function |
Q36400886 | Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis |
Q24291602 | c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK |
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