The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity

scientific journal article

The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.17-24-09407.1997
P932PMC publication ID6573428
P698PubMed publication ID9390996

P2093author name stringH Zheng
E H Koo
L H Van der Ploeg
R G Perez
P2860cites workProcessing of beta-amyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretionQ67766420
Amyloid precursor protein metabolism in primary cell cultures of neurons, astrocytes, and microgliaQ71082198
Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cellsQ71971007
Cell-surface beta-amyloid precursor protein stimulates neurite outgrowth of hippocampal neurons in an isoform-dependent mannerQ72632596
The amyloid precursor protein is developmentally regulated and correlated with synaptogenesisQ72787226
Amyloid precursor protein in cortical neurons: coexistence of two pools differentially distributed in axons and dendrites and association with cytoskeletonQ72816597
Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptidesQ22242269
Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extensionQ28513050
Embryonic expression pattern of amyloid protein precursor suggests a role in differentiation of specific subsets of neuronsQ28592569
beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activityQ28593175
The establishment of polarity by hippocampal neurons in cultureQ29616334
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptorQ29618322
Expression of the class III beta-tubulin isotype in developing neurons in culture.Q30434068
Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient miceQ33893148
Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitroQ36235391
Amyloid beta-protein as a substrate interacts with extracellular matrix to promote neurite outgrowthQ36317817
Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neuronsQ36382469
Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contactQ36416236
Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptidesQ36596465
Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch componentsQ36831631
Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavageQ37239146
Growth of a rat neuroblastoma cell line in serum-free supplemented mediumQ37313160
A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowthQ38309410
Alzheimer's disease: a central role for amyloidQ40701623
Mechanisms of neuronal degeneration in Alzheimer's diseaseQ40986730
Neural cell adhesion molecules in activity-dependent development and synaptic plasticityQ41226225
Interaction of beta-amyloid peptides with integrins in a human nerve cell lineQ41380136
Role of amyloid precursor protein (APP): study with antisense transfection of human neuroblastoma cellsQ41630684
Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesionQ41709571
The regulation of amyloid beta protein precursor secretion and its modulatory role in cell adhesionQ41760569
Integrins in point contacts mediate cell spreading: factors that regulate integrin accumulation in point contacts vs. focal contactsQ41953774
Ligand-dependent G protein coupling function of amyloid transmembrane precursorQ42066774
Amyloid beta protein enhances the survival of hippocampal neurons in vitroQ44109304
Secreted form of amyloid beta protein precursor is involved in the growth regulation of fibroblasts.Q45966280
Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injuryQ48092228
The survival of rat cerebral cortical neurons in the presence of trophic APP peptidesQ48129570
Secreted forms of beta-amyloid precursor protein modulate dendrite outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neuronsQ48151610
Intraneuronal compartments of the amyloid precursor protein.Q48258074
Functional organization of microtubule-associated protein tau. Identification of regions which affect microtubule growth, nucleation, and bundle formation in vitroQ48332155
Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor proteinQ48342880
The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowthQ48458288
MAP2 is localized to the dendrites of hippocampal neurons which develop in cultureQ48685423
GGF/neuregulin is a neuronal signal that promotes the proliferation and survival and inhibits the differentiation of oligodendrocyte progenitorsQ48956089
Modulation of the PC12 cell response to nerve growth factor by antisense oligonucleotide to amyloid precursor protein.Q53201006
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectAlzheimer's diseaseQ11081
Amyloid beta (A4) precursor proteinQ14865884
P304page(s)9407-9414
P577publication date1997-12-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleThe beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity
P478volume17

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