| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1045374950 |
| P356 | DOI | 10.1186/2051-5960-2-36 |
| P932 | PMC publication ID | 4023627 |
| P698 | PubMed publication ID | 24684730 |
| P5875 | ResearchGate publication ID | 261254348 |
| P50 | author | M Zagrebelsky | Q64498359 |
| Ulrike Herrmann | Q110135451 | ||
| P2093 | author name string | Martin Korte | |
| Thomas Deller | |||
| Christine Altmann | |||
| Julia Gobbert | |||
| Lennard Ganss | |||
| Meike Hick | |||
| Morna Gruber | |||
| Sascha W Weyer | |||
| Ulrike C Müller | |||
| P2860 | cites work | The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo | Q24306930 |
| Homo- and heterodimerization of APP family members promotes intercellular adhesion | Q24337232 | ||
| Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter | Q24337889 | ||
| Interaction of reelin with amyloid precursor protein promotes neurite outgrowth | Q24655186 | ||
| [alpha]-Secretase ADAM10 as well as [alpha]APPs is reduced in platelets and CSF of Alzheimer disease patients | Q24676332 | ||
| ADAM-10 over-expression increases cortical synaptogenesis | Q28280531 | ||
| Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons | Q28479242 | ||
| Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members | Q28504488 | ||
| Synapse-associated protein-97 mediates alpha-secretase ADAM10 trafficking and promotes its activity | Q28511294 | ||
| Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the beta-amyloid precursor protein | Q28513133 | ||
| Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene | Q28586800 | ||
| Genetic background changes the pattern of forebrain commissure defects in transgenic mice underexpressing the beta-amyloid-precursor protein | Q28587017 | ||
| The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity | Q28587197 | ||
| Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2 | Q28589908 | ||
| Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice | Q28590025 | ||
| Synaptic transmission is impaired prior to plaque formation in amyloid precursor protein-overexpressing mice without altering behaviorally-correlated sharp wave-ripple complexes | Q43506888 | ||
| Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation | Q43699789 | ||
| An image analysis algorithm for dendritic spines | Q43999998 | ||
| alpha- and beta-secretase: profound changes in Alzheimer's disease. | Q44225451 | ||
| Measurement of alpha- and beta-secretase cleaved amyloid precursor protein in cerebrospinal fluid from Alzheimer patients | Q44574707 | ||
| CSF APPs alpha and phosphorylated tau protein levels in mild cognitive impairment and dementia of Alzheimer's type | Q45789046 | ||
| Secreted amyloid precursor protein-alpha upregulates synaptic protein synthesis by a protein kinase G-dependent mechanism. | Q45999808 | ||
| Activity requires soluble amyloid precursor protein alpha to promote neurite outgrowth in neural stem cell-derived neurons via activation of the MAPK pathway. | Q46418672 | ||
| Endogenous secreted amyloid precursor protein-alpha regulates hippocampal NMDA receptor function, long-term potentiation and spatial memory | Q46515073 | ||
| The p75 neurotrophin receptor negatively modulates dendrite complexity and spine density in hippocampal neurons. | Q46776170 | ||
| Excitatory synaptic transmission is depressed in cultured hippocampal neurons of APP/PS1 mice | Q46852627 | ||
| Generation of conditional null alleles for APP and APLP2. | Q48316010 | ||
| Neurite-outgrowth regulating functions of the amyloid protein precursor of Alzheimer's disease | Q48492020 | ||
| The small pyramidal neuron of the rat cerebral cortex. The perikaryon, dendrites and spines | Q48926315 | ||
| Time-lapse imaging of granule cells in mouse entorhino-hippocampal slice cultures reveals changes in spine stability after entorhinal denervation. | Q50506713 | ||
| Decreased α-secretase-cleaved amyloid precursor protein as a diagnostic marker for Alzheimer's diseas | Q53200551 | ||
| Amyloid-beta precursor protein mediates neuronal toxicity of amyloid beta through Go protein activation. | Q53291495 | ||
| Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway. | Q53303993 | ||
| Role of phosphorylation of Alzheimer's amyloid precursor protein during neuronal differentiation. | Q53335648 | ||
| Development of identified neuronal types and of specific synaptic connections in slice cultures of rat hippocampus | Q71929476 | ||
| Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells | Q71971007 | ||
| Lamina-specific synaptic connections of hippocampal neurons in vitro | Q72299911 | ||
| The amyloid precursor protein is developmentally regulated and correlated with synaptogenesis | Q72787226 | ||
| Levels of alpha- and beta-secretase cleaved amyloid precursor protein in the cerebrospinal fluid of Alzheimer's disease patients | Q73398033 | ||
| Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein | Q28592893 | ||
| beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity | Q28593175 | ||
| Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP | Q29547505 | ||
| Morphological changes in dendritic spines associated with long-term synaptic plasticity | Q29614372 | ||
| A simple method for organotypic cultures of nervous tissue | Q29614375 | ||
| Dendritic organization in the neurons of the visual and motor cortices of the cat | Q29616515 | ||
| APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle | Q30493956 | ||
| Amyloid precursor protein (APP) regulates synaptic structure and function | Q30531725 | ||
| Reduced cerebrospinal fluid levels of alpha-secretase-cleaved amyloid precursor protein in aged rats: correlation with spatial memory deficits | Q31405199 | ||
| Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window | Q33484154 | ||
| In vivo turnover of tau and APP metabolites in the brains of wild-type and Tg2576 mice: greater stability of sAPP in the beta-amyloid depositing mice | Q33505668 | ||
| Modifications to the hand-held Gene Gun: improvements for in vitro biolistic transfection of organotypic neuronal tissue | Q34097933 | ||
| Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function. | Q34255981 | ||
| Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. | Q35000938 | ||
| APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP. | Q35052570 | ||
| Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitro | Q36235391 | ||
| Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation | Q36462366 | ||
| Novel GαS-protein signaling associated with membrane-tethered amyloid precursor protein intracellular domain. | Q36595737 | ||
| Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1. | Q36740945 | ||
| Neurotrophic and neuroprotective effects of hAPP in transgenic mice | Q36798319 | ||
| Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch components | Q36831631 | ||
| Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors | Q37427458 | ||
| Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells | Q37576797 | ||
| Upregulation of the alpha-secretase ADAM10--risk or reason for hope? | Q37688199 | ||
| Regulated intramembrane proteolysis--lessons from amyloid precursor protein processing | Q37854085 | ||
| Functions of the APP gene family in the nervous system: insights from mouse models | Q37935600 | ||
| Regulation of α-secretase ADAM10 expression and activity | Q37942089 | ||
| Roles of amyloid precursor protein family members in neuroprotection, stress signaling and aging | Q37956562 | ||
| Role of APP for dendritic spine formation and stability | Q37957630 | ||
| Physiological functions of the amyloid precursor protein secretases ADAM10, BACE1, and presenilin | Q37961473 | ||
| Physiological functions of APP family proteins | Q37987144 | ||
| Interactions between the amyloid precursor protein C-terminal domain and G proteins mediate calcium dysregulation and amyloid beta toxicity in Alzheimer's disease | Q39618623 | ||
| A macromolecular complex involving the amyloid precursor protein (APP) and the cytosolic adapter FE65 is a negative regulator of axon branching | Q39739662 | ||
| The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice. | Q40106778 | ||
| Biolistic transfection of neuronal cultures using a hand-held gene gun. | Q40150089 | ||
| Organotypic slice cultures: a technique has come of age. | Q41623986 | ||
| Amyloid precursor protein promotes post-developmental neurite arborization in the Drosophila brain | Q42263336 | ||
| Systematic regulation of spine sizes and densities in pyramidal neurons | Q42444087 | ||
| Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. | Q42495065 | ||
| Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines | Q42735982 | ||
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 36 | |
| P577 | publication date | 2014-03-31 | |
| P1433 | published in | Acta Neuropathologica Communications | Q27724912 |
| P1476 | title | Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-KO mice that is prevented by APPsα expression | |
| P478 | volume | 2 |
| Q33695377 | A new method allowing long-term potentiation recordings in hippocampal organotypic slices. |
| Q40234658 | APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission. |
| Q37594982 | APP Deletion Accounts for Age-Dependent Changes in the Bioenergetic Metabolism and in Hyperphosphorylated CaMKII at Stimulated Hippocampal Presynaptic Active Zones |
| Q28551424 | APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone |
| Q39251175 | APP Protein Family Signaling at the Synapse: Insights from Intracellular APP-Binding Proteins |
| Q39164553 | APP-A Novel Player within the Presynaptic Active Zone Proteome. |
| Q48444707 | Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity. |
| Q38856794 | Adeno-Associated Virus-Based Gene Therapy for CNS Diseases. |
| Q27301267 | Alzheimer's disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression |
| Q35855501 | Amyloid Precursor Protein Translation Is Regulated by a 3'UTR Guanine Quadruplex |
| Q37348863 | Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D-serine homeostasis |
| Q41073036 | Amyloid-precursor Like Proteins APLP1 and APLP2 Are Dispensable for Normal Development of the Neonatal Respiratory Network |
| Q58561394 | Analysis of Motor Function in Amyloid Precursor-Like Protein 2 Knockout Mice: The Effects of Ageing and Sex |
| Q35569822 | Deletion of the amyloid precursor-like protein 1 (APLP1) enhances excitatory synaptic transmission, reduces network inhibition but does not impair synaptic plasticity in the mouse dentate gyrus. |
| Q50344142 | Determination of dendritic spine morphology by the striatin scaffold protein STRN4 through interaction with the phosphatase PP2A. |
| Q54234721 | Distinct in vivo roles of secreted APP ectodomain variants APPsα and APPsβ in regulation of spine density, synaptic plasticity, and cognition. |
| Q92052671 | Editorial: Translational Control of APP Expression for Alzheimer Disease Therapy |
| Q37638090 | Entorhinal Cortex dysfunction can be rescued by inhibition of microglial RAGE in an Alzheimer's disease mouse model |
| Q91635058 | Hebbian and Homeostatic Synaptic Plasticity-Do Alterations of One Reflect Enhancement of the Other? |
| Q38608328 | Impaired theta-gamma coupling in APP-deficient mice. |
| Q49832533 | Non-cell-autonomous function of DR6 in Schwann cell proliferation. |
| Q39209681 | Not just amyloid: physiological functions of the amyloid precursor protein family |
| Q37595011 | Novel Insights into the Physiological Function of the APP (Gene) Family and Its Proteolytic Fragments in Synaptic Plasticity |
| Q37633232 | Particulate air pollutants, APOE alleles and their contributions to cognitive impairment in older women and to amyloidogenesis in experimental models |
| Q90312509 | PhIP exposure in rodents produces neuropathology potentially relevant to Alzheimer's disease |
| Q37102392 | Physiological role for amyloid precursor protein in adult experience-dependent plasticity. |
| Q95839038 | Presynaptic APP levels and synaptic homeostasis are regulated by Akt phosphorylation of Huntingtin |
| Q39214249 | Regulation of Alpha-Secretase ADAM10 In vitro and In vivo: Genetic, Epigenetic, and Protein-Based Mechanisms |
| Q47593384 | Regulation of Neurotransmitter Release by Amyloid Precursor Protein Through Synapsin Phosphorylation |
| Q42208784 | Shedding of APP limits its synaptogenic activity and cell adhesion properties. |
| Q47688609 | Soluble Amyloid Precursor Protein Alpha Interacts with alpha3-Na, K-ATPAse to Induce Axonal Outgrowth but Not Neuroprotection: Evidence for Distinct Mechanisms Underlying these Properties |
| Q38961537 | Structure and Synaptic Function of Metal Binding to the Amyloid Precursor Protein and its Proteolytic Fragments |
| Q38911059 | Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function |
| Q40874327 | The APP Intracellular Domain Is Required for Normal Synaptic Morphology, Synaptic Plasticity, and Hippocampus-Dependent Behavior. |
| Q60046056 | The Emerging Role of Mechanics in Synapse Formation and Plasticity |
| Q26750116 | The Neuroprotective Properties of the Amyloid Precursor Protein Following Traumatic Brain Injury |
| Q38766310 | The Role of APP in Structural Spine Plasticity |
| Q39414505 | The physiological role of the amyloid precursor protein as an adhesion molecule in the developing nervous system |
| Q90730208 | The β-Secretase BACE1 in Alzheimer's Disease |
| Q39145999 | Therapeutic Potential of Secreted Amyloid Precursor Protein APPsα. |
| Q40354888 | Viral gene transfer of APPsα rescues synaptic failure in an Alzheimer's disease mouse model. |
Search more.