| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1042517253 |
| P356 | DOI | 10.1038/379074A0 |
| P698 | PubMed publication ID | 8538744 |
| P50 | author | Steven Barger | Q55546650 |
| P2093 | author name string | Furukawa K | |
| Blalock EM | |||
| Mattson MP | |||
| P2860 | cites work | mSlo , a Complex Mouse Gene Encoding "Maxi" Calcium-Activated Potassium Channels | Q28298176 |
| Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors | Q34028643 | ||
| Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase | Q34292233 | ||
| Structural basis of voltage-gated K+ channel pharmacology | Q35337763 | ||
| Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor | Q35638734 | ||
| Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices | Q36342500 | ||
| Potassium channel dysfunction in fibroblasts identifies patients with Alzheimer disease | Q36517139 | ||
| The cyclic nucleotide gated channel of olfactory receptor neurons. | Q36674775 | ||
| Calcium regulation of the neuronal growth cone | Q38198282 | ||
| Physiological production of the beta-amyloid protein and the mechanism of Alzheimer's disease | Q40384269 | ||
| beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease. | Q40384274 | ||
| Calcium, free radicals, and excitotoxic neuronal death in primary cell culture | Q40402386 | ||
| From contact to connection: early events during synaptogenesis | Q40542929 | ||
| Inhibition of cGMP-dependent protein kinase by (Rp)-guanosine 3',5'-monophosphorothioates | Q41901092 | ||
| Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death | Q42482357 | ||
| Properties of single calcium-activated potassium channels of large conductance in rat hippocampal neurons in culture | Q42674317 | ||
| The secreted form of the Alzheimer's beta-amyloid precursor protein stimulates a membrane-associated guanylate cyclase | Q42822424 | ||
| Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene | Q45729428 | ||
| Secreted forms of beta-amyloid precursor protein modulate dendrite outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neurons | Q48151610 | ||
| Properties and modulation of a calcium-activated potassium channel in rat olfactory bulb neurons | Q48293481 | ||
| Involvement of amyloid precursor protein in memory formation in the rat: an indirect antibody approach | Q48331232 | ||
| Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein | Q48342880 | ||
| Learning and memory | Q54982173 | ||
| Potassium channel stimulation by natriuretic peptides through cGMP-dependent dephosphorylation | Q59063032 | ||
| Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice | Q60796700 | ||
| Modulation of IK,Ca by phorbol ester-mediated activation of PKC in pleural sensory neurons of Aplysia | Q67580160 | ||
| Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of beta-amyloid precursor | Q72169553 | ||
| P433 | issue | 6560 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 74-78 | |
| P577 | publication date | 1996-01-01 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein | |
| P478 | volume | 379 |
| Q36078010 | A role for the beta-amyloid precursor protein in memory? |
| Q29615873 | APP processing and synaptic function |
| Q52047052 | APPL, the Drosophila member of the APP-family, exhibits differential trafficking and processing in CNS neurons. |
| Q34547754 | Aberrant subcellular neuronal calcium regulation in aging and Alzheimer's disease |
| Q42447543 | Abeta25-35 induces rapid lysis of red blood cells: contrast with Abeta1-42 and examination of underlying mechanisms |
| Q35967608 | Activation of calcium-dependent potassium channels in mouse [correction of rat] brain neurons by neurotrophin-3 and nerve growth factor |
| Q37030598 | Alterations of some membrane transport proteins in Alzheimer's disease: role of amyloid beta-peptide |
| Q23923132 | Alzheimer amyloid protein precursor in the rat hippocampus: transport and processing through the perforant path |
| Q33708039 | Alzheimer's disease and neuronal network activity |
| Q52042816 | Alzheimer's disease. Short precursor shortens memory. |
| Q92589754 | Amyloid Precursor Protein (APP) and GABAergic Neurotransmission |
| Q41181063 | Amyloid beta-peptide and oxidative cellular injury in Alzheimer's disease |
| Q46048319 | Amyloid precursor protein activates phosphotyrosine signaling pathway |
| Q57899246 | Amyloid precursor protein and amyloid β-peptide bind to ATP synthase and regulate its activity at the surface of neural cells |
| Q37427458 | Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors |
| Q34083130 | Amyloid precursor protein associates independently and collaboratively with PTB and PDZ domains of mint on vesicles and at cell membrane |
| Q37269655 | Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology |
| Q33927819 | An overview of APP processing enzymes and products |
| Q26738294 | Analysis of Amyloid Precursor Protein Function in Drosophila melanogaster |
| Q37931062 | Analysis of amyloid precursor protein function in Drosophila melanogaster |
| Q44873866 | Antibodies to the C-terminus of the beta-amyloid precursor protein (APP): a site specific marker for the detection of traumatic axonal injury |
| Q34186312 | Apoptosis in neurodegenerative disorders |
| Q33891347 | Apoptotic and anti-apoptotic synaptic signaling mechanisms |
| Q48656687 | Autoradiographic characterization of [3H]cGMP binding sites in the rat brain |
| Q41475139 | Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders |
| Q90083096 | Beyond the Ligand: Extracellular and Transcellular G Protein-Coupled Receptor Complexes in Physiology and Pharmacology |
| Q28201256 | Calcium-activated potassium channel SK1- and IK1-like immunoreactivity in injured human sensory neurones and its regulation by neurotrophic factors |
| Q34569825 | Caloric restriction and intermittent fasting: two potential diets for successful brain aging |
| Q33836230 | Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases. |
| Q73138933 | Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease |
| Q48115360 | Chemically induced, activity-independent LTD elicited by simultaneous activation of PKG and inhibition of PKA. |
| Q37459278 | Cholinergic agonists stimulate secretion of soluble full-length amyloid precursor protein in neuroendocrine cells |
| Q33948010 | Computational study of hippocampal-septal theta rhythm changes due to β-amyloid-altered ionic channels |
| Q35038663 | Contributions of mitochondrial alterations, resulting from bad genes and a hostile environment, to the pathogenesis of Alzheimer's disease |
| Q33602355 | Cyclic GMP and ion channel regulation |
| Q73393741 | Cyclic GTP imitates the potentiating effect of the nootrope vinpocetine on the high-threshold A-current in mollusk neurons |
| Q44075104 | Decreases in Ca2+-dependent K+-currents due to cyclic guanosine monophosphate are not dependent on phosphorylation. |
| Q36329164 | Development of beta-amyloid-induced neurodegeneration in Alzheimer's disease and novel neuroprotective strategies. |
| Q71603554 | Differential effect of tacrine and physostigmine on the secretion of the beta-amyloid precursor protein in cell lines |
| Q43794693 | Differential effects of unaggregated and aggregated amyloid beta protein (1-40) on K(+) channel currents in primary cultures of rat cerebellar granule and cortical neurones |
| Q34995125 | Do apoptotic mechanisms regulate synaptic plasticity and growth-cone motility? |
| Q48559543 | Down-regulation of the amyloid protein precursor of Alzheimer's disease by antisense oligonucleotides reduces neuronal adhesion to specific substrata |
| Q33842845 | Dual role of protein kinase C on BK channel regulation. |
| Q34509797 | Dysregulation of cellular calcium homeostasis in Alzheimer's disease: bad genes and bad habits |
| Q41133930 | Ectodomain phosphorylation of beta-amyloid precursor protein at two distinct cellular locations |
| Q33591587 | Effects of amyloid precursor protein derivatives and oxidative stress on basal forebrain cholinergic systems in Alzheimer's disease |
| Q33807200 | Effects of serine/threonine protein phosphatases on ion channels in excitable membranes |
| Q41210086 | Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory |
| Q45713208 | Evidence for D-aspartyl-beta-amyloid secretase activity in human brain |
| Q28202177 | Excitotoxic and Excitoprotective Mechanisms: Abundant Targets for the Prevention and Treatment of Neurodegenerative Disorders |
| Q48313645 | Exercise and BDNF reduce Aβ production by enhancing α-secretase processing of APP. |
| Q44177170 | Expression of human amyloid precursor protein in rat cortical neurons inhibits calcium oscillations. |
| Q36436323 | Extracellular ATP inhibits the small-conductance K channel on the apical membrane of the cortical collecting duct from mouse kidney |
| Q41707879 | Free radicals, calcium, and the synaptic plasticity-cell death continuum: emerging roles of the transcription factor NF kappa B. |
| Q82467947 | Functional consequences of the lack of amyloid precursor protein in the mouse dentate gyrus in vivo |
| Q37965817 | Functions of Aβ, sAPPα and sAPPβ : similarities and differences |
| Q37935600 | Functions of the APP gene family in the nervous system: insights from mouse models |
| Q37060402 | GFAP expression and social deficits in transgenic mice overexpressing human sAPPα. |
| Q28590025 | Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice |
| Q91904075 | Glutamate Receptor Trafficking and Protein Synthesis Mediate the Facilitation of LTP by Secreted Amyloid Precursor Protein-Alpha |
| Q74272693 | Guanosine 3',5'-cyclic monophosphate mediated inhibition of cell death induced by nerve growth factor withdrawal and beta-amyloid: protective effects of propentofylline |
| Q35679568 | Holo-APP and G-protein-mediated signaling are required for sAPPα-induced activation of the Akt survival pathway. |
| Q31808112 | Hyperglycemic but not normoglycemic global ischemia induces marked early intraneuronal expression of beta-amyloid precursor protein. |
| Q37961730 | Identification and biology of α-secretase. |
| Q33505668 | In vivo turnover of tau and APP metabolites in the brains of wild-type and Tg2576 mice: greater stability of sAPP in the beta-amyloid depositing mice |
| Q39461532 | Increasing age reduces expression of long-term depression and dynamic range of transmission plasticity in CA1 field of the rat hippocampus. |
| Q36156106 | Interaction of ASK1 and the beta-amyloid precursor protein in a stress-signaling complex |
| Q37636324 | Intracellular calcium signalling in Alzheimer's disease |
| Q48531630 | Involvement of amyloid precursor protein in functional synapse formation in cultured hippocampal neurons |
| Q48543481 | Involvement of superoxide in pathogenic action of mutations that cause Alzheimer's disease |
| Q34019137 | Ionic and signal transduction alterations in Alzheimer's disease: relevance of studies on peripheral cells |
| Q41344757 | Ionic effects of the Alzheimer's disease beta-amyloid precursor protein and its metabolic fragments |
| Q92920915 | Linking Molecular Pathways and Large-Scale Computational Modeling to Assess Candidate Disease Mechanisms and Pharmacodynamics in Alzheimer's Disease |
| Q35897595 | Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10. |
| Q34378951 | Mechanisms of amyloid beta protein-induced modification in ion transport systems: implications for neurodegenerative diseases |
| Q40986730 | Mechanisms of neuronal degeneration in Alzheimer's disease |
| Q36530142 | Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice. |
| Q42495065 | Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. |
| Q40907904 | Mitogen-activated protein kinase is involved in N-methyl-D-aspartate receptor regulation of amyloid precursor protein cleavage |
| Q34711201 | Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior |
| Q33705813 | Network Excitability Dysfunction in Alzheimer's Disease: Insights from In Vitro and In Vivo Models |
| Q37393152 | Neuroinflammation and copper in Alzheimer's disease. |
| Q35196248 | Neuronal and glial calcium signaling in Alzheimer's disease |
| Q36934762 | Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease |
| Q48339755 | Neuronal death induced by SIN-1 in the presence of superoxide dismutase: protection by cyclic GMP. |
| Q48122406 | Neuroprotective effects of DETA-NONOate, a nitric oxide donor, on hydrogen peroxide-induced neurotoxicity in cortical neurones |
| Q43782682 | Neurotoxic and neuroprotective effects of glutamate are enhanced by introduction of amyloid precursor protein cDNA. |
| Q33771224 | Neurotoxic and synaptic effects of okadaic acid, an inhibitor of protein phosphatases |
| Q32077110 | Nicotine and its interaction with beta-amyloid protein: a short review |
| Q48682190 | Nitric oxide increases stimulation-evoked acetylcholine release from rat hippocampal slices by a cyclic GMP-independent mechanism |
| Q78094837 | Nitric oxide protects PC12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling |
| Q28587148 | No hippocampal neuron or synaptic bouton loss in learning-impaired aged beta-amyloid precursor protein-null mice |
| Q44031795 | Non-steroidal anti-inflammatory drugs stimulate secretion of non-amyloidogenic precursor protein |
| Q77508966 | Novel domain-specific actions of amyloid precursor protein on developing synapses |
| Q40481988 | Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide. |
| Q42509583 | PP1 inhibitors depolarize Hermissenda photoreceptors and reduce K+ currents |
| Q35550999 | Perturbed signal transduction in neurodegenerative disorders involving aberrant protein aggregation |
| Q36523591 | Physiological roles for amyloid beta peptides |
| Q53222316 | Post-translational processing and turnover kinetics of presynaptically targeted amyloid precursor superfamily proteins in the central nervous system. |
| Q48348892 | Potassium conductance causing hyperpolarization of CA1 hippocampal neurons during hypoxia |
| Q28592853 | Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis |
| Q34995120 | Presenilins and APP in neuritic and synaptic plasticity: implications for the pathogenesis of Alzheimer's disease |
| Q41856782 | Prevention of Alzheimer's disease in high risk groups: statin therapy in subjects with PSEN1 mutations or heterozygosity for apolipoprotein E epsilon 4 |
| Q42519822 | Protein phosphatase 2A is essential for the activation of Ca2+-activated K+ currents by cGMP-dependent protein kinase in tracheal smooth muscle and Chinese hamster ovary cells |
| Q30327647 | Protein phosphatase 5 in signal transduction. |
| Q28254104 | Proteolytic processing of Alzheimer's β-amyloid precursor protein |
| Q41382883 | Receptor-regulated ion channels |
| Q35214792 | Regulation and critical role of potassium homeostasis in apoptosis |
| Q38002193 | Relationships between the amyloid precursor protein and its various proteolytic fragments and neuronal systems |
| Q38929253 | Restoring Soluble Amyloid Precursor Protein α Functions as a Potential Treatment for Alzheimer's Disease. |
| Q46614690 | Reversible ischemia increases levels of Alzheimer amyloid protein precursor without increasing levels of mRNA in the rabbit spinal cord |
| Q48127954 | Role of the outward delayed rectifier K+ current in ceramide-induced caspase activation and apoptosis in cultured cortical neurons |
| Q28202553 | Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory |
| Q37956562 | Roles of amyloid precursor protein family members in neuroprotection, stress signaling and aging |
| Q26825226 | Roles of the amyloid precursor protein family in the peripheral nervous system |
| Q38217975 | Ryanodine receptors: physiological function and deregulation in Alzheimer disease. |
| Q93046766 | Secreted Amyloid Precursor Protein-Alpha Promotes Arc Protein Synthesis in Hippocampal Neurons |
| Q48538138 | Secreted amyloid precursor protein alpha selectively suppresses N-methyl-D-aspartate currents in hippocampal neurons: involvement of cyclic GMP. |
| Q42475584 | Secreted form of amyloid precursor protein enhances basal glucose and glutamate transport and protects against oxidative impairment of glucose and glutamate transport in synaptosomes by a cyclic GMP-mediated mechanism |
| Q48487682 | Secreted form of beta-amyloid precursor protein activates protein kinase C and phospholipase Cgamma1 in cultured embryonic rat neocortical cells |
| Q36462366 | Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation |
| Q73207470 | Study of the sugar chains of recombinant human amyloid precursor protein produced by Chinese hamster ovary cells |
| Q73320577 | Suppression of an amyloid beta peptide-mediated calcium channel response by a secreted beta-amyloid precursor protein |
| Q35050266 | Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels |
| Q53391777 | TAGing APP constrains neurogenesis. |
| Q40304525 | TRF2 dysfunction elicits DNA damage responses associated with senescence in proliferating neural cells and differentiation of neurons. |
| Q48424611 | Telomerase mediates the cell survival-promoting actions of brain-derived neurotrophic factor and secreted amyloid precursor protein in developing hippocampal neurons. |
| Q52572881 | The Drosophila beta-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction. |
| Q30497430 | The KATP Channel Activator Diazoxide Ameliorates Amyloid-β and Tau Pathologies and Improves Memory in the 3xTgAD Mouse Model of Alzheimer's Disease |
| Q48617239 | The actin-severing protein gelsolin modulates calcium channel and NMDA receptor activities and vulnerability to excitotoxicity in hippocampal neurons. |
| Q39118352 | The amyloid precursor protein represses expression of acetylcholinesterase in neuronal cell lines |
| Q33863439 | The beta-amyloid precursor protein and its derivatives: from biology to learning and memory processes |
| Q38184783 | The dark sides of amyloid in Alzheimer's disease pathogenesis |
| Q34067209 | The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex |
| Q35027419 | The effect of a secreted form of beta-amyloid-precursor protein on intracellular Ca2+ increase in rat cultured hippocampal neurones |
| Q33799169 | The evolution of aging-related brain change |
| Q43754809 | The human serotonin 5-HT4 receptor regulates secretion of non-amyloidogenic precursor protein. |
| Q32143300 | The nootropic drug vinpocetine modulates different types of potassium currents in molluscan neurons |
| Q41188058 | The pharmacology and molecular biology of large-conductance calcium-activated (BK) potassium channels |
| Q74589707 | The role of calcium in apoptosis |
| Q74552056 | The role of glycoproteins in neural development function, and disease |
| Q41753871 | The role of the amyloid protein precursor (APP) in Alzheimer's disease: does the normal function of APP explain the topography of neurodegeneration? |
| Q35534062 | The roles of amyloid precursor protein (APP) in neurogenesis: Implications to pathogenesis and therapy of Alzheimer disease |
| Q39831551 | Thyroid hormones reverse the UV-induced repression of APP in neuroblastoma cells. |
| Q48101376 | Tyrosine kinase A-nerve growth factor receptor is antigenically present in dystrophic neurites from a variety of conditions but not in Alzheimer's disease. |
| Q47431150 | Understanding the roles of mutations in the amyloid precursor protein in Alzheimer disease. |
| Q53226580 | Vascular nitric oxide may lessen Alzheimer's risk. |
| Q40354888 | Viral gene transfer of APPsα rescues synaptic failure in an Alzheimer's disease mouse model. |
| Q34390785 | Voltage-gated potassium channels at the crossroads of neuronal function, ischemic tolerance, and neurodegeneration |
| Q40933432 | hFE65L influences amyloid precursor protein maturation and secretion |
| Q39640944 | l-3-n-Butylphthalide regulates amyloid precursor protein processing by PKC and MAPK pathways in SK-N-SH cells over-expressing wild type human APP695 |
| Q36951145 | β-Secretase: its biology as a therapeutic target in diseases |
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