Protein phosphatase 2A is essential for the activation of Ca2+-activated K+ currents by cGMP-dependent protein kinase in tracheal smooth muscle and Chinese hamster ovary cells

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Protein phosphatase 2A is essential for the activation of Ca2+-activated K+ currents by cGMP-dependent protein kinase in tracheal smooth muscle and Chinese hamster ovary cells is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.271.33.19760
P698PubMed publication ID8702682
P5875ResearchGate publication ID14499028

P2093author name stringKorth M
Hofmann F
Ruth P
Zhou XB
Schlossmann J
P2860cites workImproved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patchesQ22337395
Serine/threonine protein phosphatasesQ24528215
Mode of action of iberiotoxin, a potent blocker of the large conductance Ca(2+)-activated K+ channelQ24534368
The function of calcium in the potassium permeability of human erythrocytesQ28184377
Beta-adrenergic agonists regulate KCa channels in airway smooth muscle by cAMP-dependent and -independent mechanismsQ34121141
Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plantsQ34188529
Multiple types of voltage-dependent Ca2+-activated K+ channels of large conductance in rat brain synaptosomal membranes.Q34260347
Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinaseQ34292233
Functional dependence of Ca(2+)-activated K+ current on L- and N-type Ca2+ channels: differences between chicken sympathetic and parasympathetic neurons suggest different regulatory mechanismsQ35139372
The structure, role, and regulation of type 1 protein phosphatasesQ35255480
Virus proteins that counteract host immune defensesQ35369721
A patch-clamp study of K(+)-channel activity in bovine isolated tracheal smooth muscle cellsQ35888699
Transfected cGMP-dependent protein kinase suppresses calcium transients by inhibition of inositol 1,4,5-trisphosphate productionQ36188558
Pharmacology of Protein Kinase InhibitorsQ36213534
Stimulatory and inhibitory regulation of calcium-activated potassium channels by guanine nucleotide-binding proteinsQ37306892
The physiological role of calcium-dependent channelsQ38208887
Varieties of calcium-activated potassium channelsQ38624036
NO at workQ40630836
Potassium channels in airway smooth muscle: a tale of two channelsQ40713409
Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein.Q41240734
Actions of nitroglycerine on the membrane and mechanical properties of smooth muscles of the coronary artery of the pig.Q42115003
Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kineticsQ42163759
The control of the contraction of myocytes from guinea-pig heart by the resting membrane potentialQ42713374
Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle.Q50773580
Hyperpolarization and relaxation of arterial smooth muscle caused by nitric oxide derived from the endothelium.Q50879461
Maxi K+ channels are stimulated by cyclic guanosine monophosphate-dependent protein kinase in canine coronary artery smooth muscle cellsQ54048962
Regulation of Ca2+-dependent K+-channel activity in tracheal myocytes by phosphorylation.Q54105209
A family of calcium-dependent potassium channels from rat brain.Q54116987
The sensitivity ofHelix aspersaneurones to injected calcium ionsQ54640188
Potassium channel stimulation by natriuretic peptides through cGMP-dependent dephosphorylationQ59063032
P433issue33
P407language of work or nameEnglishQ1860
P304page(s)19760-19767
P577publication date1996-08-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleProtein phosphatase 2A is essential for the activation of Ca2+-activated K+ currents by cGMP-dependent protein kinase in tracheal smooth muscle and Chinese hamster ovary cells
P478volume271

Reverse relations

cites work (P2860)
Q466539393-Morpholinosydnonimine (SIN-1) and K(+) channels in smooth muscle cells of the rabbit and guinea pig carotid arteries
Q48304000A cGMP-dependent protein kinase (PKG) controls synaptic transmission tolerance to acute oxidative stress at the Drosophila larval neuromuscular junction
Q40784958A molecular switch for specific stimulation of the BKCa channel by cGMP and cAMP kinase
Q39853582A novel dephosphorylation-activated conductance in a mouse renal collecting duct cell line
Q24315844A novel human Cl(-) channel family related to Drosophila flightless locus
Q73665675A protein phosphatase is involved in the cholinergic suppression of the Ca(2+)-activated K(+) current sI(AHP) in hippocampal pyramidal neurons
Q42507586Activation of myosin light chain phosphatase in intact arterial smooth muscle during nitric oxide-induced relaxation
Q36089810Activation of the cGMP/Protein Kinase G Pathway by Nitric Oxide Can Decrease TRPV1 Activity in Cultured Rat Dorsal Root Ganglion Neurons
Q37125720Afferent arteriolar dilation to 11, 12-EET analogs involves PP2A activity and Ca2+-activated K+ Channels.
Q39495779Alleviating brain stress: what alternative animal models have revealed about therapeutic targets for hypoxia and anoxia
Q47100287Altered Synaptic Membrane Retrieval after Strong Stimulation of Cerebellar Granule Neurons in Cyclic GMP-Dependent Protein Kinase II (cGKII) Knockout Mice
Q30370554Angiotensin II type 2 receptor regulates ROMK-like K⁺ channel activity in the renal cortical collecting duct during high dietary K⁺ adaptation
Q34785622Bidirectional control of BK channel open probability by CAMKII and PKC in medial vestibular nucleus neurons
Q36951665CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels
Q45921441Calcium-dependent and calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle.
Q37432026Complex phosphatase regulation of Ca2+-activated Cl- currents in pulmonary arterial smooth muscle cells
Q33942138Controlling anoxic tolerance in adult Drosophila via the cGMP-PKG pathway
Q33602355Cyclic GMP and ion channel regulation
Q37420916Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics
Q50523046Cyclic GMP-dependent but G-kinase-independent inhibition of Ca2+-dependent Cl- currents by NO donors in cat tracheal smooth muscle.
Q44075104Decreases in Ca2+-dependent K+-currents due to cyclic guanosine monophosphate are not dependent on phosphorylation.
Q46900043Differential mechanisms underlying the modulation of delayed-rectifier K+ channel in mouse neocortical neurons by nitric oxide
Q41576484Distinct and specific functions of cGMP-dependent protein kinases
Q33842845Dual role of protein kinase C on BK channel regulation.
Q33807200Effects of serine/threonine protein phosphatases on ion channels in excitable membranes
Q38597218Endothelial nitric oxide synthase: From biochemistry and gene structure to clinical implications of NOS3 polymorphisms
Q73870704Endothelium-dependent frequency modulation of Ca2+ signalling in individual vascular smooth muscle cells of the rat
Q36436323Extracellular ATP inhibits the small-conductance K channel on the apical membrane of the cortical collecting duct from mouse kidney
Q33978637Functional insights into modulation of BKCa channel activity to alter myometrial contractility
Q37543214Hydrogen sulfide regulates Ca(2+) homeostasis mediated by concomitantly produced nitric oxide via a novel synergistic pathway in exocrine pancreas
Q73406677Influence of age on nitric oxide modulatory action on Na(+), K(+)-ATPase activity through cyclic GMP pathway in proximal rat trachea
Q46440229Inhibition of carbachol-evoked oscillatory currents by the NO donor sodium nitroprusside in guinea-pig ileal myocytes.
Q44349317Inhibition of cyclic guanosine 5'-monophosphate-dependent protein kinase I (PKG-I) in lumbar spinal cord reduces formalin-induced hyperalgesia and PKG upregulation
Q35674540M2 muscarinic receptors induce airway smooth muscle activation via a dual, Gbetagamma-mediated inhibition of large conductance Ca2+-activated K+ channel activity.
Q36494644Melatonin inhibits nitric oxide signaling by increasing PDE5 phosphorylation in coronary arteries
Q28361669Modulation of Kv3 potassium channels expressed in CHO cells by a nitric oxide-activated phosphatase
Q28505912Molecular basis for PP2A regulatory subunit B56alpha targeting in cardiomyocytes
Q33294839Natural variation in the thermotolerance of neural function and behavior due to a cGMP-dependent protein kinase
Q43184397Nitric oxide (NO)-induced activation of large conductance Ca2+-dependent K+ channels (BK(Ca)) in smooth muscle cells isolated from the rat mesenteric artery.
Q42509583PP1 inhibitors depolarize Hermissenda photoreceptors and reduce K+ currents
Q42325400Palmitoylation and membrane association of the stress axis regulated insert (STREX) controls BK channel regulation by protein kinase C
Q73680763Pregnancy switches adrenergic signal transduction in rat and human uterine myocytes as probed by BKCa channel activity
Q91938507Protective Role of α-Calcitonin Gene-Related Peptide in Cardiovascular Diseases
Q35540282Protein Phosphatases in Plants
Q34389011Protein kinases: tuners of the BKCa channel in smooth muscle.
Q30327647Protein phosphatase 5 in signal transduction.
Q37259560Regulation of cardiac excitation and contraction by p21 activated kinase-1
Q42436569Regulation of large calcium-activated potassium channels by protein phosphatase 2A.
Q39810145Role of cGMP-kinase II in the control of renin secretion and renin expression
Q27693957Role of serine-threonine phosphoprotein phosphatases in smooth muscle contractility
Q35958555Stimulation of the cardiac myocyte Na+-K+ pump due to reversal of its constitutive oxidative inhibition.
Q52697971Suppression of spreading depression-like events in locusts by inhibition of the NO/cGMP/PKG pathway.
Q38982437The augmentation of BK channel activity by nitric oxide signaling in rat cerebral arteries involves co-localized regulatory elements
Q35951118The biology of cyclic GMP-dependent protein kinases
Q50741449The large conductance, voltage-dependent, and calcium-sensitive K+ channel, Hslo, is a target of cGMP-dependent protein kinase phosphorylation in vivo.
Q34077885The regulation of BK channel activity by pre- and post-translational modifications
Q34281889Type 1 phosphatase, a negative regulator of cardiac function
Q24608094WD40 repeat proteins striatin and S/G(2) nuclear autoantigen are members of a novel family of calmodulin-binding proteins that associate with protein phosphatase 2A
Q34357629cGMP-dependent protein kinase and the regulation of vascular smooth muscle cell gene expression: possible involvement of Elk-1 sumoylation
Q34244951cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action

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