| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | R J Davis | |
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 459-67 | |
| P577 | publication date | 1995-12-01 | |
| P1433 | published in | Molecular Reproduction and Development | Q6895976 |
| P1476 | title | Transcriptional regulation by MAP kinases | |
| P478 | volume | 42 |
| Q54964221 | A Role for p38MAPK/HSP27 Pathway in Smooth Muscle Cell Migration |
| Q40896676 | A conditionally-active form of MEK1 results in autocrine tranformation of human and mouse hematopoietic cells. |
| Q39852571 | A regulatory mechanism for RSK2 NH(2)-terminal kinase activity |
| Q34206534 | A regulatory role for p38 delta MAPK in keratinocyte differentiation. Evidence for p38 delta-ERK1/2 complex formation |
| Q34768386 | A role for K-ras in conferring resistance to the MEK inhibitor, CI-1040. |
| Q42029877 | A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase |
| Q41878046 | AP1 transcription factors in epidermal differentiation and skin cancer |
| Q41716419 | Activation and signal transduction via mitogen-activated protein (MAP) kinases in T lymphocytes |
| Q44126738 | Activation of mitogen-activated protein kinases (MAPKs) by aromatic hydrocarbons: role in the regulation of aryl hydrocarbon receptor (AHR) function |
| Q41666458 | Activation of the 9E3/cCAF chemokine by phorbol esters occurs via multiple signal transduction pathways that converge to MEK1/ERK2 and activate the Elk1 transcription factor |
| Q28210840 | Activation of the EphA2 tyrosine kinase stimulates the MAP/ERK kinase signaling cascade |
| Q43661702 | Activation of tomato PR and wound-related genes by a mutagenized tomato MAP kinase kinase through divergent pathways |
| Q39922817 | Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src |
| Q40715854 | Adhesion-related kinase repression of gonadotropin-releasing hormone gene expression requires Rac activation of the extracellular signal-regulated kinase pathway |
| Q36973814 | Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy |
| Q33975117 | Altered extracellular signal-regulated kinase signaling and glycogen metabolism in skeletal muscle from p90 ribosomal S6 kinase 2 knockout mice |
| Q48443396 | An essential role for a MEK-C/EBP pathway during growth factor-regulated cortical neurogenesis |
| Q35002186 | Antiproliferative effects of cucurbitacin B in breast cancer cells: down-regulation of the c-Myc/hTERT/telomerase pathway and obstruction of the cell cycle |
| Q41729929 | Biology of chronic myelogenous leukemia |
| Q42257831 | Bis-Retinoid A2E Induces an Increase of Basic Fibroblast Growth Factor via Inhibition of Extracellular Signal-Regulated Kinases 1/2 Pathway in Retinal Pigment Epithelium Cells and Facilitates Phagocytosis |
| Q40482310 | Bisphosphonates and estrogens inhibit osteocyte apoptosis via distinct molecular mechanisms downstream of extracellular signal-regulated kinase activation. |
| Q34068968 | Both the polycythemia- and anemia-inducing strains of Friend spleen focus-forming virus induce constitutive activation of the Raf-1/mitogen-activated protein kinase signal transduction pathway |
| Q40350530 | CCAAT/enhancer-binding protein phosphorylation biases cortical precursors to generate neurons rather than astrocytes in vivo. |
| Q34094495 | CDK8 is a positive regulator of transcriptional elongation within the serum response network |
| Q35549511 | CXCR1 and CXCR2 silencing modulates CXCL8-dependent endothelial cell proliferation, migration and capillary-like structure formation |
| Q27021588 | CXCR2: a target for pancreatic cancer treatment? |
| Q24532201 | Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: critical role of the p38 C-terminal domain in its negative regulation |
| Q44529077 | Cell cycle aberrations by alpha-synuclein over-expression and cyclin B immunoreactivity in Lewy bodies. |
| Q42991738 | Characterization of p96h2bk: immunoreaction with an anti-Erk(extracellular-signal-regulated kinase) peptide antibody and activity in Xenopus oocytes and eggs |
| Q33255705 | Characterization, localization and possible anti-inflammatory function of rat histone H4 mRNA variants |
| Q24324902 | Cloning, human chromosomal assignment, and adipose and hepatic expression of the CL-6/INSIG1 gene |
| Q37109227 | Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia. |
| Q27733875 | Crystal structure of p38 mitogen-activated protein kinase |
| Q33510461 | Data recovery and integration from public databases uncovers transformation-specific transcriptional downregulation of cAMP-PKA pathway-encoding genes |
| Q34994888 | Death pathways triggered by activated Ras in cancer cells |
| Q28590184 | Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis |
| Q90101920 | Dibutyltin alters immune cell production of the pro-inflammatory cytokines interleukin (IL) 1β and IL-6: role of mitogen-activated protein kinases and changes in mRNA |
| Q54194255 | Dibutyltin-induced alterations of interleukin 1beta secretion from human immune cells. |
| Q33949436 | Discordance between the binding affinity of mitogen-activated protein kinase subfamily members for MAP kinase phosphatase-2 and their ability to activate the phosphatase catalytically |
| Q37183212 | Down-Regulation of Ribosomal S6 kinase RPS6KA6 in Acute Myeloid Leukemia Patients. |
| Q40864626 | ERK signalling in metastatic human MDA-MB-231 breast carcinoma cells is adapted to obtain high urokinase expression and rapid cell proliferation |
| Q35062606 | ERK-associated changes of AP-1 proteins during fear extinction |
| Q73975321 | Effect of Flos carthami on stress-activated protein kinase activity in the isolated reperfused rat heart |
| Q40877375 | Effects of deregulated RAF and MEK1 expression on the cytokine-dependency of hematopoietic cells. |
| Q40804306 | Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells |
| Q52530509 | Endocrine disruptors signal the need for receptor models and mechanisms to inform policy. |
| Q35673434 | Endosulfan upregulates AP-1 binding and ARE-mediated transcription via ERK1/2 and p38 activation in HepG2 cells |
| Q43559925 | Epidermal growth factor induction of apolipoprotein A-I is mediated by the Ras-MAP kinase cascade and Sp1. |
| Q33893378 | Epidermal growth factor receptor dependence of radiation-induced transcription factor activation in human breast carcinoma cells |
| Q80066496 | ErbB2 receptor tyrosine kinase signaling mediates early demyelination induced by leprosy bacilli |
| Q34503194 | Eriodictyol inhibits RSK2-ATF1 signaling and suppresses EGF-induced neoplastic cell transformation |
| Q40733606 | Erk 1/2 differentially regulates the expression from the 1G/2G single nucleotide polymorphism in the MMP-1 promoter in melanoma cells |
| Q35101922 | Erk in kidney diseases |
| Q30780718 | Estradiol-induced phosphorylation of ERK1/2 in explants of the mouse cerebral cortex: the roles of heat shock protein 90 (Hsp90) and MEK2. |
| Q48287209 | Estrogen-induced activation of mitogen-activated protein kinase in cerebral cortical explants: convergence of estrogen and neurotrophin signaling pathways. |
| Q36699939 | Evidence for the Possible Biological Significance of the igf-1 Gene Alternative Splicing in Prostate Cancer |
| Q41105949 | Exploring the cross talk between ER stress and inflammation in age-related macular degeneration. |
| Q40730809 | Expression of c-Myc, c-Fos, and c-jun in hepatocellular carcinoma |
| Q77800270 | Expression of mixed lineage kinase 2 in germ cells of the testis |
| Q89966159 | FCTP-WSRC: Protein-Protein Interactions Prediction via Weighted Sparse Representation Based Classification |
| Q35158942 | Farnesyl transferase inhibitors in myeloid malignancies |
| Q34296103 | G-protein-coupled receptors and signaling networks: emerging paradigms. |
| Q44319940 | Gene expression profiling of ciliary neurotrophic factor-overexpressing rat striatal progenitor cells (ST14A) indicates improved stress response during the early stage of differentiation |
| Q38049482 | Gene mutations associated with anomalies of human gonad formation |
| Q36808028 | Glucocorticoid regulation of CD38 expression in human airway smooth muscle cells: role of dual specificity phosphatase 1. |
| Q30165460 | Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction. |
| Q35601582 | Growth factor receptor cross-talk with estrogen receptor as a mechanism for tamoxifen resistance in breast cancer |
| Q22007971 | Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors |
| Q34626038 | Human Mas-related G protein-coupled receptors-X1 induce chemokine receptor 2 expression in rat dorsal root ganglia neurons and release of chemokine ligand 2 from the human LAD-2 mast cell line |
| Q43713575 | Hyperosmotic stress activates the insulin receptor in CHO cells |
| Q40891222 | IL-4 regulation of IL-6 production involves Rac/Cdc42- and p38 MAPK-dependent pathways in keratinocytes |
| Q43625066 | Identification of dual specificity phosphatases induced by olfactory bulbectomy in rat olfactory neuroepithelium |
| Q77578767 | Identification of specific nuclear protein kinase C isozymes and accelerated protein kinase C-dependent nuclear protein phosphorylation during myocardial ischemia |
| Q28305571 | Identification of two essential phosphorylated threonine residues in the catalytic domain of Mekk1. Indirect activation by Pak3 and protein kinase C |
| Q73524352 | Impaired signal transduction in mitogen activated rat splenic lymphocytes during aging |
| Q77363665 | Inhibition of rat hepatocyte proliferation by transforming growth factor beta and glucagon is associated with inhibition of ERK2 and p70 S6 kinase |
| Q36194601 | Interleukin-7 in T-cell acute lymphoblastic leukemia: an extrinsic factor supporting leukemogenesis? |
| Q24540351 | JLP: A scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors. |
| Q71574085 | JNK (c-Jun NH2-terminal kinase) is a target for antioxidants in T lymphocytes |
| Q73196381 | Kinetic mechanism and ATP-binding site reactivity of p38gamma MAP kinase |
| Q33585885 | Leishmania major MPK7 protein kinase activity inhibits intracellular growth of the pathogenic amastigote stage |
| Q47152861 | Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration |
| Q39788129 | Lung fibrotic responses to particle exposure |
| Q35937724 | MAP kinases and the adaptive response to hypertonicity: functional preservation from yeast to mammals |
| Q29619955 | MAPK cascade signalling and synaptic plasticity |
| Q35546507 | MAPK regulation of gene expression in airway smooth muscle |
| Q28139990 | MEKK3 directly regulates MEK5 activity as part of the big mitogen-activated protein kinase 1 (BMK1) signaling pathway |
| Q48438287 | Mechanisms of action of ladasten: activation of gene expression for neurotrophins and mitogen-activated kinases |
| Q24673182 | Mechanotransduction in skeletal muscle |
| Q34772742 | Minimotif miner: a computational tool to investigate protein function, disease, and genetic diversity |
| Q36573219 | Mitogen-activated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation |
| Q35409040 | Mitogen-activated protein kinase kinase kinase 1 (MAP3K1) integrates developmental signals for eyelid closure |
| Q43660286 | Mitogen-activated protein kinases are in vivo transducers of osmosensory signals in fish gill cells |
| Q43457477 | Molecular effects of genistein on male urethral development. |
| Q33962208 | Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity |
| Q37919395 | Molecular oncology of lung cancer |
| Q24554271 | Multiple ras downstream pathways mediate functional repression of the homeobox gene product TTF-1 |
| Q47676649 | NGF induces transient but not sustained activation of ERK in PC12 mutant cells incapable of differentiating |
| Q38172953 | Neuronal activity-regulated gene transcription: how are distant synaptic signals conveyed to the nucleus? |
| Q36793931 | Neuroplasticity in brain reward circuitry following a history of ethanol dependence |
| Q30478978 | Neurotrophin/Trk receptor signaling mediates C/EBPalpha, -beta and NeuroD recruitment to immediate-early gene promoters in neuronal cells and requires C/EBPs to induce immediate-early gene transcription. |
| Q86630316 | New directions for studying the role of free radicals in aging |
| Q28206453 | Novel protein kinase C isoforms regulate human keratinocyte differentiation by activating a p38 delta mitogen-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha |
| Q33842800 | Oestrogen and growth factor cross-talk and endocrine insensitivity and acquired resistance in breast cancer |
| Q36982854 | Opioid modulation of extracellular signal-regulated protein kinase activity is ras-dependent and involves Gbetagamma subunits |
| Q43667398 | Ovarian hormones elicit phosphorylation of Akt and extracellular-signal regulated kinase in explants of the cerebral cortex. |
| Q33853144 | Oxidative stress and gene regulation |
| Q33623018 | POSSIBLE REGULATION OF LDL-RECEPTOR BY NARINGENIN IN HEPG2 HEPATOMA CELL LINE. |
| Q33618711 | Parthenolide suppresses non-small cell lung cancer GLC-82 cells growth via B-Raf/MAPK/Erk pathway |
| Q24537383 | Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases |
| Q33784945 | Phosphorylation of the human cytomegalovirus 86-kilodalton immediate-early protein IE2. |
| Q24675210 | Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation |
| Q42802895 | Platelet-derived growth factor (PDGF) receptor-alpha activates c-Jun NH2-terminal kinase-1 and antagonizes PDGF receptor-beta -induced phenotypic transformation |
| Q35721356 | Predicting protein-protein interactions based only on sequences information |
| Q36146332 | Predicting protein-protein interactions via multivariate mutual information of protein sequences |
| Q62516274 | Predicting response to BET inhibitors using computational modeling: A BEAT AML project study |
| Q36370766 | Preferential signaling and induction of allergy-promoting lymphokines upon weak stimulation of the high affinity IgE receptor on mast cells. |
| Q33930614 | Proteasome- and p38-dependent regulation of ERK3 expression |
| Q40666301 | Quercetin suppresses proinflammatory cytokines production through MAP kinases andNF-kappaB pathway in lipopolysaccharide-stimulated macrophage |
| Q36435760 | RSK2 as a key regulator in human skin cancer |
| Q30437023 | RSK2 mediates muscle cell differentiation through regulation of NFAT3. |
| Q28209994 | Regulation of SPIN90 Phosphorylation and Interaction with Nck by ERK and Cell Adhesion |
| Q28578262 | Regulation of carbamoyl phosphate synthetase by MAP kinase |
| Q46776194 | Regulation of homocysteine-induced MMP-9 by ERK1/2 pathway |
| Q42520428 | Regulation of translation during in vitro maturation of bovine oocytes: the role of MAP kinase, eIF4E (cap binding protein) phosphorylation, and eIF4E-BP1. |
| Q28589966 | Rhes is involved in striatal function |
| Q30437044 | Ribosomal S6 kinase 2 is a key regulator in tumor promoter induced cell transformation |
| Q42835042 | Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways |
| Q35564914 | Role of Gastrointestinal Hormones in the Proliferation of Normal and Neoplastic Tissues |
| Q30306356 | Role of MAP kinase in the enhanced cell proliferation of long term estrogen deprived human breast cancer cells |
| Q37284634 | Role of mitogen-activated protein kinase in cardiac hypertrophy and heart failure |
| Q37392558 | Role of p38 MAP Kinase Signal Transduction in Solid Tumors |
| Q28363036 | Role of p38 MAP kinase in LPS-induced airway inflammation in the rat |
| Q51360555 | Role of p38 mitogen-activated protein kinase in cardiac myocyte secretion of the inflammatory cytokine TNF-alpha. |
| Q34966603 | Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging |
| Q37865381 | Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy. |
| Q42544735 | Serum- and growth-factor-free three-dimensional culture system supports cartilage tissue formation by promoting collagen synthesis via Sox9-Col2a1 interaction |
| Q35606623 | Sexual experience in female rodents: cellular mechanisms and functional consequences |
| Q42797686 | Signaling from G protein-coupled receptors to the c-jun promoter involves the MEF2 transcription factor. Evidence for a novel c-jun amino-terminal kinase-independent pathway. |
| Q33943855 | Single-cell analysis of signal transduction in CD4 T cells stimulated by antigen in vivo |
| Q73500676 | Specific Activation of a c-Jun NH2-terminal Kinase Isoform and Induction of Neurite Outgrowth in PC-12 Cells by Staurosporine |
| Q41665482 | Specific regulation of fos family transcription factors in thymocytes at two developmental checkpoints |
| Q42795938 | Standard isolation of primary adipose cells from mouse epididymal fat pads induces inflammatory mediators and down-regulates adipocyte genes |
| Q43623857 | Stimulation of astrocyte-enriched culture with C2 ceramide increases proenkephalin mRNA: involvement of cAMP-response element binding protein and mitogen activated protein kinases |
| Q40435051 | Structural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist |
| Q27641774 | Structural basis for p38alpha MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity |
| Q35634933 | Suppression of coronavirus replication by inhibition of the MEK signaling pathway |
| Q54983787 | Suppression of the ERK-SRF axis facilitates somatic cell reprogramming. |
| Q35085354 | Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis |
| Q40802206 | Synergistic effects of pi3k/akt on abrogation of cytokine-dependency induced by oncogenic raf. |
| Q33711156 | T cell signaling: a decision of life and death |
| Q28202079 | TC21 mediates transformation and cell survival via activation of phosphatidylinositol 3-kinase/Akt and NF-kappaB signaling pathway |
| Q27002288 | Targeted therapy for hepatocellular carcinoma: novel agents on the horizon |
| Q33823577 | Targeting signal transduction pathways to eliminate chemotherapeutic drug resistance and cancer stem cells. |
| Q40154931 | Targeting the RAF/MEK/ERK, PI3K/AKT and p53 pathways in hematopoietic drug resistance. |
| Q37945533 | The "SWOT" of BRAF inhibition in melanoma: RAF inhibitors, MEK inhibitors or both? |
| Q34241295 | The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors |
| Q57025490 | The Role of Hydrogen Peroxide in Redox-Dependent Signaling: Homeostatic and Pathological Responses in Mammalian Cells |
| Q34503476 | The dual roles of c-Jun NH2-terminal kinase signaling in Cr(VI)-induced apoptosis in JB6 cells |
| Q37135451 | The intertwining of structure and function: proposed helix-swapping of the SH2 domain of Grb7, a regulatory protein implicated in cancer progression and inflammation |
| Q34329950 | The late-domain-containing protein p6 is the predominant phosphoprotein of human immunodeficiency virus type 1 particles |
| Q33957461 | The mitogen-activated protein kinase signaling pathway stimulates mos mRNA cytoplasmic polyadenylation during Xenopus oocyte maturation |
| Q35826251 | The role of the extracellular signal-regulated kinase pathway in cerebellar abnormalities in schizophrenia |
| Q34432656 | The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase |
| Q22010608 | The structure of phosphorylated p38gamma is monomeric and reveals a conserved activation-loop conformation |
| Q42217527 | Tipifarnib in the treatment of acute myeloid leukemia |
| Q28363102 | Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation |
| Q42806232 | Transcriptional regulation of prostaglandin synthase 2 gene expression by platelet-derived growth factor and serum |
| Q34215427 | Transgenic analysis of the Leishmania MAP kinase MPK10 reveals an auto-inhibitory mechanism crucial for stage-regulated activity and parasite viability. |
| Q37586472 | Translation initiation: a critical signalling node in cancer |
| Q77413362 | Translocation (1;22) in refractory anemia and the prognostic significance of karyotypic abnormalities in refractory anemia |
| Q35582631 | Tributyltin alters secretion of interleukin 1 beta from human immune cells |
| Q33721426 | Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation |
| Q33490144 | Utilizing ras signaling pathway to direct selective replication of herpes simplex virus-1. |
| Q40072183 | VEGF modulation of retinal pigment epithelium resistance |
| Q38302532 | c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation |
| Q38363441 | cAMP inhibits the proliferation of retinal pigmented epithelial cells through the inhibition of ERK1/2 in a PKA-independent manner |
| Q104500143 | miR-31-5p Promotes Proliferation and Inhibits Apoptosis of Goat Hair Follicle Stem Cells by Targeting RASA1/MAP3K1 pathway |
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