Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials

scientific article

Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CHOM.2012.10.017
P932PMC publication ID3638032
P698PubMed publication ID23245326
P5875ResearchGate publication ID233939083

P50authorWilliam DeGradoQ8007696
Swapnil KulkarniQ125350688
Satish MishraQ56550209
Maria KowalskaQ67196707
P2093author name stringKatie B Freeman
Lawrence W Bergman
Thomas M Daly
Doron C Greenbaum
Michael J Costanzo
Richard W Scott
Wenxi Pan
Photini Sinnis
Mortimer Poncz
Hyunil Jo
Robert W Kavash
Melissa S Love
Melanie G Millholland
Dewight R Williams
P2860cites workTransgenic mice studies demonstrate a role for platelet factor 4 in thrombosis: dissociation between anticoagulant and antithrombotic effect of heparinQ75424151
Extended depth of field imaging for high speed cell analysisQ79722363
A new world malaria map: Plasmodium falciparum endemicity in 2010Q17485680
Artemisinin and a Series of Novel Endoperoxide Antimalarials Exert Early Effects on Digestive Vacuole MorphologyQ22061805
Human malaria parasites in continuous cultureQ28131626
Antimicrobial peptides of multicellular organismsQ28131811
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening AssaysQ28145712
Modular determinants of antimicrobial activity in platelet factor-4 family kinocidinsQ33268976
Platelet-induced clumping of Plasmodium falciparum-infected erythrocytes from Malawian patients with cerebral malaria-possible modulation in vivo by thrombocytopeniaQ33378117
Role of the platelet chemokine platelet factor 4 (PF4) in hemostasis and thrombosisQ33387477
Channel-forming properties of cecropins and related model compounds incorporated into planar lipid membranesQ33631782
Amphipathic, alpha-helical antimicrobial peptidesQ33994626
Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malariaQ34105789
Antimicrobial peptides from human plateletsQ34258124
Magainins and the disruption of membrane-linked free-energy transductionQ34300587
Can innate immunity be enhanced to treat microbial infections?Q35777677
Trafficking of plasmepsin II to the food vacuole of the malaria parasite Plasmodium falciparumQ36321745
Platelet factor 4 mediates inflammation in experimental cerebral malariaQ37016412
De novo designed synthetic mimics of antimicrobial peptidesQ37321460
Potential of immunomodulatory host defense peptides as novel anti-infectivesQ37580524
Cationic peptides: a new source of antibioticsQ41714967
Platelets kill intraerythrocytic malarial parasites and mediate survival to infectionQ46131528
Membrane thinning caused by magainin 2.Q46338877
Thrombocytopenia in African children can predict the severity of malaria caused by Plasmodium falciparum and the prognosis of the disease.Q47932672
The antimalarial activity of N-benzyloxydihydrotriazines. I. The activity of clociguanil (BRL 50216) against rodent malaria, and studies on its mode of actionQ47990666
Cytokine profiles for human V gamma 9+ T cells stimulated by Plasmodium falciparumQ47998642
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectantimalarialQ521616
Platelet factor 4Q3740205
Platelet factor 4Q14905361
antimicrobial humoral immune response mediated by antimicrobial peptideQ28598481
P304page(s)815-23
P577publication date2012-12-13
P1433published inCell Host & MicrobeQ5058153
P1476titlePlatelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials
P478volume12

Reverse relations

cites work (P2860)
Q35039046A high-content phenotypic screen reveals the disruptive potency of quinacrine and 3',4'-dichlorobenzamil on the digestive vacuole of Plasmodium falciparum
Q36687059Activated Neutrophils Are Associated with Pediatric Cerebral Malaria Vasculopathy in Malawian Children
Q56450312Aryl-alkyl-lysines: small molecular membrane-active antiplasmodial agents
Q34979366CD36 recruits α₅β₁ integrin to promote cytoadherence of P. falciparum-infected erythrocytes
Q26830743Chemokine-Derived Peptides: Novel Antimicrobial and Antineoplasic Agents
Q33927528Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria
Q92537315ELF4 facilitates innate host defenses against Plasmodium by activating transcription of Pf4 and Ppbp
Q64447648Effects of host-derived chemokines on the motility and viability of Trypanosoma brucei
Q40162581Elimination of Babesia microti Is Dependent on Intraerythrocytic Killing and CD4+ T Cells
Q27016553Emerging roles for platelets as immune and inflammatory cells
Q33406904Emphasis on the Role of PF4 in the Incidence, Pathophysiology and Treatment of Heparin Induced Thrombocytopenia
Q26772866Expanding the antimalarial toolkit: Targeting host-parasite interactions
Q85789610Host response: PF4 - platelets' poison
Q33673156Human antimicrobial peptides and proteins
Q38103059Immunobiology of Plasmodium in liver and brain
Q30179429Involvement of β-defensin 130 (DEFB130) in the macrophage microbicidal mechanisms for killing Plasmodium falciparum
Q35781198Membrane-Active Small Molecules: Designs Inspired by Antimicrobial Peptides
Q40768743New insights into the protective power of platelets in malaria infection
Q39009853Platelet secretion in inflammatory and infectious diseases
Q92351178Platelet α-granules contribute to organ-specific pathologies in a mouse model of severe malaria
Q50257338Platelet-Specific Chemokines Contribute to the Pathogenesis of Acute Lung Injury
Q38160535Platelets as immune cells in infectious diseases.
Q26739670Platelets in Pulmonary Immune Responses and Inflammatory Lung Diseases
Q56358763Platelets kill circulating parasites of all major Plasmodium species in human malaria
Q38211899Platelets: at the nexus of antimicrobial defence
Q52370717The Emerging Role of Pattern Recognition Receptors in the Pathogenesis of Malaria.
Q90401541The Era of Thromboinflammation: Platelets Are Dynamic Sensors and Effector Cells During Infectious Diseases
Q59335689The Platelet Response to Tissue Injury
Q38666558The immunological balance between host and parasite in malaria

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