The Platelet Response to Tissue Injury

The Platelet Response to Tissue Injury is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FMED.2018.00317
P932PMC publication ID6242949
P698PubMed publication ID30483508

P2093author name stringHarald F Langer
Johannes Patzelt
Felix Eisinger
P2860cites workPlatelets and matrix metalloproteinasesQ87110830
Effects of P-Selectin Antagonist Inclacumab in Patients Undergoing Coronary Artery Bypass Graft Surgery: SELECT-CABG TrialQ87132714
Platelets prime hematopoietic and vascular niche to drive angiocrine-mediated liver regenerationQ89473734
The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophagesQ22253155
Identification of the platelet ADP receptor targeted by antithrombotic drugsQ24290845
Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophilsQ24293111
Inhibition of Angiogenesis by Recombinant Human Platelet Factor-4 and Related PeptidesQ24298587
Platelet factor 4 is chemotactic for neutrophils and monocytesQ24302223
CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cellsQ24310570
Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factorQ24317407
Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombinQ24563384
Platelets mediate cytotoxic T lymphocyte-induced liver damageQ24604707
Central role of the P2Y12 receptor in platelet activationQ24618777
Interleukin-1beta induced vascular permeability is dependent on induction of endothelial tissue factor (TF) activityQ24813092
Thymidine Phosphorylase Participates in Platelet Signaling and Promotes ThrombosisQ27339642
Platelets and vascular integrity: how platelets prevent bleeding in inflammationQ47297561
Platelet-mediated modulation of adaptive immunity. A communication link between innate and adaptive immune compartmentsQ47749276
An autologous platelet-rich plasma hydrogel compound restores left ventricular structure, function and ameliorates adverse remodeling in a minimally invasive large animal myocardial restoration model: a translational approach: Vu and Pal "MyocardialQ47751186
Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration.Q47828127
CLEC-2 contributes to hemostasis independently of classical hemITAM signaling in mice.Q47914114
P2y12 Receptor Promotes Pressure Overload-Induced Cardiac Remodeling via Platelet-Driven Inflammation in MiceQ47924569
Heterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapies.Q48748541
Platelets kill bacteria by bridging innate and adaptive immunity via PF4 and FcγRIIA.Q49922542
Circulating Platelets as Mediators of Immunity, Inflammation, and ThrombosisQ49953603
Angiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactor.Q49967364
Complement links platelets to innate immunityQ50092930
Platelets recruit human dendritic cells via Mac-1/JAM-C interaction and modulate dendritic cell function in vitro.Q50335763
A monoclonal antibody to a membrane glycoprotein binds only to activated platelets.Q50921115
Tamoxifen Directly Inhibits Platelet Angiogenic Potential and Platelet-Mediated Metastasis.Q51155744
Novel role of platelet reactivity in adverse left ventricular remodelling after ST-segment elevation myocardial infarction: The REMODELING Trial.Q51157196
Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevationQ28218789
Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factorQ28236903
Role of platelet P-selectin and microparticle PSGL-1 in thrombus formationQ28254159
Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarialsQ28281539
Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic bloodQ28294906
Purification and properties of an endothelial cell growth factor from human plateletsQ28300487
Trousseau's syndrome: multiple definitions and multiple mechanismsQ28301882
Platelet-derived serotonin mediates liver regenerationQ28306257
Angiogenic factorQ28306483
Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagenQ28364081
Platelets induce apoptosis during sepsis in a contact-dependent manner that is inhibited by GPIIb/IIIa blockadeQ28481577
Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient MiceQ29615196
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodiaQ29617501
Thrombocidins, microbicidal proteins from human blood platelets, are C-terminal deletion products of CXC chemokinesQ29871535
Influenza virus H1N1 activates platelets through FcγRIIA signaling and thrombin generation.Q30360587
Inflammation induces hemorrhage in thrombocytopeniaQ30481913
Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosisQ30497499
Platelet TGF-β1 contributions to plasma TGF-β1, cardiac fibrosis, and systolic dysfunction in a mouse model of pressure overload.Q30504664
Activated platelets mediate inflammatory signaling by regulated interleukin 1beta synthesisQ30663963
Platelet shape change is mediated by both calcium-dependent and -independent signaling pathways. Role of p160 Rho-associated coiled-coil-containing protein kinase in platelet shape changeQ33178933
Highly accumulated platelet vascular endothelial growth factor in coagulant thrombotic regionQ33195948
Platelets are necessary for airway wall remodeling in a murine model of chronic allergic inflammationQ33356884
Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhageQ33369958
Platelets and platelet-derived serotonin promote tissue repair after normothermic hepatic ischemia in miceQ33374023
The GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bendQ33381441
Platelets actively sequester angiogenesis regulatorsQ33387520
Platelet factor 4 binds to bacteria, [corrected] inducing antibodies cross-reacting with the major antigen in heparin-induced thrombocytopeniaQ33392361
Coronary artery remodeling in a model of left ventricular pressure overload is influenced by platelets and inflammatory cellsQ33402947
Platelet ITAM signaling is critical for vascular integrity in inflammationQ33405485
Crosstalk between platelets and the complement system in immune protection and diseaseQ33410188
Single platelets seal neutrophil-induced vascular breaches via GPVI during immune-complex-mediated inflammation in mice.Q33423339
Nouvelle cuisine: platelets served with inflammationQ33423427
Platelets activate a pathogenic response to blood-stage Plasmodium infection but not a protective immune responseQ33438503
Platelet factor 4 limits Th17 differentiation and cardiac allograft rejectionQ37524290
Treatment of chronic non-healing ulcers using autologous platelet rich plasma: a case seriesQ37668205
Platelets: linking hemostasis and cancerQ37808901
Platelets and the immune continuumQ37857647
Platelet adhesion and activation mechanisms in arterial thrombosis and ischaemic strokeQ37903934
Secretable Storage Pools in PlateletsQ38077642
Platelets: at the nexus of antimicrobial defenceQ38211899
P-selectin mediates Ca(2+)-dependent adhesion of activated platelets to many different types of leukocytes: detection by flow cytometryQ38327910
Platelets and the complement cascade in atherosclerosisQ38382518
Integrin αIIbβ3 outside-in signaling.Q38644725
The platelet membrane glycoprotein IIb-IIIa complex.Q39195582
Microenvironmental regulation of tumour angiogenesisQ39433862
Thymidine phosphorylase in cancer cells stimulates human endothelial cell migration and invasion by the secretion of angiogenic factors.Q39579208
Amplification of bacteria-induced platelet activation is triggered by FcγRIIA, integrin αIIbβ3, and platelet factor 4.Q39675280
Native thrombocidin-1 and unfolded thrombocidin-1 exert antimicrobial activity via distinct structural elementsQ39709081
Dual blockade of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (FGF-2) exhibits potent anti-angiogenic effectsQ39808173
TREM-1 ligand expression on platelets enhances neutrophil activationQ40220719
Long-term use of ticagrelor in patients with prior myocardial infarctionQ40263764
Platelet microparticles: a transcellular delivery system for RANTES promoting monocyte recruitment on endotheliumQ40423150
Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injuryQ40703820
c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.Q40792572
Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis.Q40845943
Role of platelet P-selectin and CD40 ligand in the induction of monocytic tissue factor expressionQ40849254
Angiopoietin-1 protects the adult vasculature against plasma leakage.Q40890338
A Novel Cobra Venom Metalloproteinase, Mocarhagin, Cleaves a 10-Amino Acid Peptide from the Mature N Terminus of P-selectin Glycoprotein Ligand Receptor, PSGL-1, and Abolishes P-selectin BindingQ41271814
Platelet-Eosinophil Interactions As a Potential Therapeutic Target in Allergic Inflammation and AsthmaQ41334017
Platelet-derived interleukin 1 induces human endothelial adhesion molecule expression and cytokine productionQ41851230
Expression of functional CD40 by vascular endothelial cellsQ41981036
Thymidine phosphorylase, 2-deoxy-D-ribose and angiogenesisQ42072484
An evidence-based evaluation on the use of platelet rich plasma in orthopedics - a review of the literatureQ42372962
CD40 ligand stimulates proinflammatory cytokine production by human endothelial cellsQ42453856
Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphateQ42872500
Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancerQ43202368
Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic miceQ43489161
Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxidesQ44001004
TGF-beta1 released from activated platelets can induce TNF-stimulated human brain endothelium apoptosis: a new mechanism for microvascular lesion during cerebral malariaQ44440629
The significance of thymidine phosphorylase/platelet-derived endothelial cell growth factor activity in renal cell carcinomaQ44544385
Principal role of glycoprotein VI in alpha2beta1 and alphaIIbbeta3 activation during collagen-induced thrombus formationQ44961840
Platelet factor 4/CXCL4 induces phagocytosis and the generation of reactive oxygen metabolites in mononuclear phagocytes independently of Gi protein activation or intracellular calcium transientsQ44987493
CD40 ligand enhances monocyte tissue factor expression and thrombin generation via oxidative stress in patients with hypercholesterolemiaQ45209480
Aggravation of viral hepatitis by platelet-derived serotoninQ45218233
Platelet-monocyte complexes support monocyte adhesion to endothelium by enhancing secondary tethering and cluster formationQ45345579
Integrity of kindlin-2 FERM subdomains is required for supporting integrin activation.Q45984456
Platelet derived bFGF mediates vascular integrative mechanisms of mesenchymal stem cells in vitroQ46070845
Platelets kill intraerythrocytic malarial parasites and mediate survival to infectionQ46131528
Quantitative immunofluorescence mapping reveals little functional coclustering of proteins within platelet α-granulesQ46590284
Leukocyte engagement of platelet glycoprotein Ibalpha via the integrin Mac-1 is critical for the biological response to vascular injuryQ46783981
Anti-apoptotic effect of sphingosine-1-phosphate and platelet-derived growth factor in human embryonic stem cells.Q46875342
Prasugrel versus clopidogrel in patients with acute coronary syndromesQ46915044
The podoplanin-CLEC-2 axis inhibits inflammation in sepsisQ47095108
Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: an autocrine mechanism contributing to angiogenesisQ36256017
Crosstalk between SDF-1/CXCR4 and SDF-1/CXCR7 in cardiac stem cell migrationQ36291077
Platelets in inflammation and atherogenesis.Q36328825
P-Selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein E-deficient miceQ36375890
Platelet activation leads to activation and propagation of the complement systemQ36403387
Platelet-derived CD154 enables T-cell priming and protection against Listeria monocytogenes challengeQ36508925
Platelet secretion is kinetically heterogeneous in an agonist-responsive mannerQ36509648
CCL5 derived from platelets increases megakaryocyte proplatelet formationQ36596892
Expression of platelet-derived endothelial cell growth factor (PD-ECGF) and its mRNA in uterine cervical cancersQ36617594
Beneficial suicide: why neutrophils die to make NETsQ36882473
Proteomic analysis of platelet alpha-granules using mass spectrometryQ36920727
Platelet-derived SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regenerationQ36950818
Endothelial sprouting and angiogenesis: matrix metalloproteinases in the leadQ37031727
Platelet-mediated angiogenesis is independent of VEGF and fully inhibited by aspirinQ37327359
MKEY, a Peptide Inhibitor of CXCL4-CCL5 Heterodimer Formation, Protects Against Stroke in MiceQ37364433
Role of tissue factor in cancerQ37393391
Mechanisms of vessel branching: filopodia on endothelial tip cells lead the way.Q37407600
Anticoagulation inhibits tumor cell-mediated release of platelet angiogenic proteins and diminishes platelet angiogenic response.Q37429687
Thrombosis: tangled up in NETsQ33556910
Activated platelets interfere with recruitment of mesenchymal stem cells to apoptotic cardiac cells via high mobility group box 1/Toll-like receptor 4-mediated down-regulation of hepatocyte growth factor receptor METQ33676193
Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα.Q33815771
Human plasma epidermal growth factor/beta-urogastrone is associated with blood plateletsQ33821869
Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesisQ33896683
A role for the chemokine RANTES in regulating CD8 T cell responses during chronic viral infectionQ33981265
Novel anti-bacterial activities of β-defensin 1 in human platelets: suppression of pathogen growth and signaling of neutrophil extracellular trap formation.Q34079154
Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis.Q34081690
The final steps of integrin activation: the end gameQ34106011
Platelets in Inflammation and ThrombosisQ34263823
Role of thymidine phosphorylase activity in the angiogenic effect of platelet derived endothelial cell growth factor/thymidine phosphorylase.Q34293624
Platelet factor 4 and Duffy antigen required for platelet killing of Plasmodium falciparumQ34316582
Granule-mediated release of sphingosine-1-phosphate by activated plateletsQ34470276
Serotonin reverts age-related capillarization and failure of regeneration in the liver through a VEGF-dependent pathwayQ34582994
Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet alpha granules and differentially releasedQ34584213
Talin-dependent integrin activation is required for fibrin clot retraction by plateletsQ34667580
Thymidine phosphorylase is angiogenic and promotes tumor growth.Q34672542
A novel role for platelet secretion in angiogenesis: mediating bone marrow-derived cell mobilization and homing.Q34870640
Platelet-derived serotonin links vascular disease and tissue fibrosisQ34973681
Lipopolysaccharide signaling without a nucleus: kinase cascades stimulate platelet shedding of proinflammatory IL-1β-rich microparticlesQ35001472
Hepatocyte growth factor-mediated attraction of mesenchymal stem cells for apoptotic neuronal and cardiomyocytic cellsQ35011205
A novel conditional platelet depletion mouse model reveals the importance of platelets in protection against Staphylococcus aureus bacteremia.Q35060782
Rapidly in situ forming platelet-rich plasma gel enhances angiogenic responses and augments early wound healing after open abdomenQ35079444
Release of angiogenesis regulatory proteins from platelet alpha granules: modulation of physiologic and pathologic angiogenesisQ35153802
PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytesQ35160019
The evolving role of platelets in inflammation.Q35206747
History of discovery: platelet-derived growth factorQ35531909
Should we use platelet-rich plasma as an adjunct therapy to treat "acute wounds," "burns," and "laser therapies": A review and a proposal of a quality criteria checklist for further studiesQ35561644
Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptorQ35751021
P-selectin promotes neutrophil extracellular trap formation in miceQ35836873
Platelets at the interface of thrombosis, inflammation, and cancer.Q35904932
Role of the SDF-1/CXCR4 axis in the pathogenesis of lung injury and fibrosisQ36013707
Platelets induce apoptosis via membrane-bound FasL.Q36070471
Platelets secrete stromal cell-derived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivoQ36238074
Platelets in angiogenesis.Q51629116
RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium.Q54014329
Alpha-granule pool of glycoprotein IIb-IIIa in normal and pathologic platelets and megakaryocytes.Q54097821
Platelet associated fibrinogen and ICAM-2 induce firm adhesion of neutrophils under flow conditions.Q54122924
Sphingosine 1-phosphate has anti-apoptotic effect on liver sinusoidal endothelial cells and proliferative effect on hepatocytes in a paracrine manner in human.Q54311594
Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury.Q54693969
Thrombin induces the release of angiopoietin-1 from platelets.Q55034619
Platelets kill circulating parasites of all major Plasmodium species in human malariaQ56358763
SDF-1α/CXCR4 Axis Is Instrumental in Neointimal Hyperplasia and Recruitment of Smooth Muscle Progenitor CellsQ56921714
Heterophilic interactions of platelet factor 4 and RANTES promote monocyte arrest on endotheliumQ57574602
A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3Q58657596
VEGF-A/VEGFR-2 and FGF-2/FGFR-1 but not PDGF-BB/PDGFR-β play important roles in promoting immature and inflammatory intraplaque angiogenesisQ58765708
Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent plateletsQ59065667
Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5Q60622970
CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanismQ63354517
Purification of thymidine phosphorylase from human amniochorionQ67415054
The platelet count and mean platelet volumeQ70820014
TNF-alpha renders human neutrophils responsive to platelet factor 4. Comparison of PF-4 and IL-8 reveals different activity profiles of the two chemokinesQ70988422
Neutrophil rolling, arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the beta 2-integrin CD11b/CD18Q71249326
Interleukin-1 induces interleukin-8 secretion from endothelial cells by a juxtacrine mechanismQ72891615
Vitronectin receptor (alpha(v)beta3) mediates platelet adhesion to the luminal aspect of endothelial cells: implications for reperfusion in acute myocardial infarctionQ73762713
Characterization of soluble CD40 ligand released from human activated plateletsQ74568777
Platelet-derived growth factor inhibits basic fibroblast growth factor angiogenic properties in vitro and in vivo through its alpha receptorQ77725457
Trophic effects of platelets on cultured endothelial cells are mediated by platelet-associated fibroblast growth factor-2 (FGF-2) and vascular endothelial growth factor (VEGF)Q78505144
Platelet P-selectin facilitates atherosclerotic lesion developmentQ78654773
Thrombin-induced interleukin 1beta synthesis in platelet suspensions: impact of contaminating leukocytesQ79966043
Platelet-derived stromal cell-derived factor-1 regulates adhesion and promotes differentiation of human CD34+ cells to endothelial progenitor cellsQ80217129
Distinct antithrombotic consequences of platelet glycoprotein Ibalpha and VI deficiency in a mouse model of arterial thrombosisQ80233007
Platelet factor 4 (CXC chemokine ligand 4) differentially regulates respiratory burst, survival, and cytokine expression of human monocytes by using distinct signaling pathwaysQ80736159
Platelet-derived microparticles induce angiogenesis and stimulate post-ischemic revascularizationQ81723006
Distinct platelet packaging, release, and surface expression of proangiogenic and antiangiogenic factors on different platelet stimuliQ83433659
P-selectin ligation induces platelet activation and enhances microaggregate and thrombus formationQ84159495
Stromal cell-derived factor-1 enhances wound healing through recruiting bone marrow-derived mesenchymal stem cells to the wound area and promoting neovascularizationQ85600449
Platelets and neurovascular inflammationQ86700895
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)317
P577publication date2018-01-01
P1433published inFrontiers in MedicineQ27726181
P1476titleThe Platelet Response to Tissue Injury
P478volume5

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cites work (P2860)
Q90582635Complement and coagulation cascades in trauma
Q100307106Female sex as an independent prognostic factor in the development of oral mucositis during autologous peripheral stem cell transplantation
Q96225006Immunomodulatory effects of platelets on the severity of hand, foot, and mouth disease infected with enterovirus 71
Q98727151Interactions at engineered graft-tissue interfaces: A review
Q92983665The dual role of platelet-innate immune cell interactions in thrombo-inflammation

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