Sphingosine 1-phosphate has anti-apoptotic effect on liver sinusoidal endothelial cells and proliferative effect on hepatocytes in a paracrine manner in human.

scientific article published on 28 November 2014

Sphingosine 1-phosphate has anti-apoptotic effect on liver sinusoidal endothelial cells and proliferative effect on hepatocytes in a paracrine manner in human. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/HEPR.12446
P8608Fatcat IDrelease_wsnwrsti4rarrc5nbazaon7fu4
P698PubMed publication ID25371278

P50authorKen NakayamaQ56274772
Nobuhiro OhkohchiQ57697655
P2093author name stringKen Nakayama
Naoya Ikeda
Soichiro Murata
Kiyoshi Fukunaga
Naoki Sano
Takehito Maruyama
Takeshi Nowatari
Reiji Nozaki
P2860cites workSphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3Q24532043
International Union of Pharmacology. XXXIV. Lysophospholipid receptor nomenclatureQ28201589
Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosisQ28283313
Liver regenerationQ29614743
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell deathQ29620000
Sphingosine-1-phosphate: an enigmatic signalling lipidQ29620563
Ghrelin inhibits AGEs-induced apoptosis in human endothelial cells involving ERK1/2 and PI3K/Akt pathwaysQ33836120
Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptorsQ34691444
The BCL-2 family reunionQ35568029
Mechanisms of cardioprotection by lysophospholipidsQ35838996
In vitro and in vivo modulation of vascular barrier integrity by sphingosine 1-phosphate: mechanistic insightsQ35923020
Sphingosine 1-phosphate and its receptors: an autocrine and paracrine networkQ36184401
Correlated morphometric and biochemical studies on the liver cell. I. Morphometric model, stereologic methods, and normal morphometric data for rat liverQ36534772
BH3-only proteins and their roles in programmed cell deathQ37566201
Scavenger functions of the liver endothelial cellQ37874716
Clearance function of scavenger endothelial cellsQ38794779
Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase-9 in the absence of Apaf-1.Q39527416
Establishment of an immortalized human-liver endothelial cell line with SV40T and hTERT.Q40551032
TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytesQ40797297
Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis.Q40845943
Regulation of cell survival by sphingosine-1-phosphate receptor S1P1 via reciprocal ERK-dependent suppression of Bim and PI-3-kinase/protein kinase C-mediated upregulation of Mcl-1.Q42854212
Activation of human liver sinusoidal endothelial cell by human platelets induces hepatocyte proliferationQ42975901
MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activityQ43083934
Sphingosine 1-phosphate protects human umbilical vein endothelial cells from serum-deprived apoptosis by nitric oxide productionQ43514142
The caspase inhibitor IDN-6556 prevents caspase activation and apoptosis in sinusoidal endothelial cells during liver preservation injuryQ44347302
Hepatocyte growth factor induces Mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt.Q48003529
Sphingosine 1-phosphate attenuates peroxide-induced apoptosis in HaCaT cells cultured in vitro.Q50849369
Erythrocytes store and release sphingosine 1-phosphate in blood.Q51084957
Hepatic sinusoidal endothelial cells promote hepatocyte proliferation early after partial hepatectomy in rats.Q51188846
Massive liver growth in mice induced by systemic interleukin 6 administration.Q51835027
P433issue11
P921main subjectapoptotic processQ14599311
P304page(s)1136-1145
P577publication date2014-11-28
P1433published inHepatology ResearchQ15752035
P1476titleSphingosine 1-phosphate has anti-apoptotic effect on liver sinusoidal endothelial cells and proliferative effect on hepatocytes in a paracrine manner in human.
P478volume45

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cites work (P2860)
Q41573128A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation.
Q41769236HDL-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 & S1P3 receptors on vascular endothelium
Q41827554New drug delivery system for liver sinusoidal endothelial cells for ischemia-reperfusion injury
Q28071893Platelets: No longer bystanders in liver disease
Q100467649Serum Sphingosine-1-Phosphate Is Decreased in Patients With Acute-on-Chronic Liver Failure and Predicts Early Mortality
Q39376014Sphingosine kinase and sphingosine-1-phosphate in liver pathobiology
Q59335689The Platelet Response to Tissue Injury

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