scholarly article | Q13442814 |
P356 | DOI | 10.1194/JLR.M600514-JLR200 |
P698 | PubMed publication ID | 17284776 |
P2093 | author name string | Robert S Parker | |
Timothy J Sontag | |||
P2860 | cites work | Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4 | Q22004251 |
Expression and molecular cloning of human liver leukotriene B4 omega-hydroxylase (CYP4F2) gene | Q22010557 | ||
Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver | Q24313469 | ||
Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp60(c-Src) kinase activation and death of HT4 neuronal cells | Q28142722 | ||
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Ligand specificity in the CRAL-TRIO protein family | Q28206484 | ||
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Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol | Q28298967 | ||
Increased atherosclerosis in hyperlipidemic mice deficient in alpha -tocopherol transfer protein and vitamin E | Q28344980 | ||
Characterization of human liver leukotriene B(4) omega-hydroxylase P450 (CYP4F2). | Q31389061 | ||
Alpha- and gamma-tocotrienols are metabolized to carboxyethyl-hydroxychroman derivatives and excreted in human urine | Q32051277 | ||
d-alpha-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties | Q33654586 | ||
Allosteric phenomena in cytochrome P450-catalyzed monooxygenations | Q34370833 | ||
gamma-tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells | Q35307368 | ||
Analysis of human cytochrome P450 3A4 cooperativity: construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics | Q36481303 | ||
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Tocopherols are metabolized in HepG2 cells by side chain omega-oxidation and consecutive beta-oxidation | Q40794302 | ||
omega-hydroxylation activity toward leukotriene B(4) and polyunsaturated fatty acids in the human hepatoblastoma cell line, HepG2, and human lung adenocarcinoma cell line, A549. | Q40845440 | ||
Alpha-tocopherol affects the urinary and biliary excretion of 2,7,8-trimethyl-2 (2'-carboxyethyl)-6-hydroxychroman, gamma-tocopherol metabolite, in rats | Q43658026 | ||
The nitration product 5-nitro-gamma-tocopherol is increased in the Alzheimer brain | Q43915384 | ||
Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E status | Q43984576 | ||
Measurement of vitamin E metabolites by high-performance liquid chromatography during high-dose administration of alpha-tocopherol | Q44355787 | ||
Cell death caused by selenium deficiency and protective effect of antioxidants | Q44530918 | ||
Selective accumulation of alpha-tocopherol in Drosophila is associated with cytochrome P450 tocopherol-omega-hydroxylase activity but not alpha-tocopherol transfer protein | Q46804639 | ||
Model for the interaction of membrane-bound substrates and enzymes. Hydrolysis of ganglioside GD1a by sialidase of neuronal membranes isolated from calf brain | Q48888942 | ||
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P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1090-8 | |
P577 | publication date | 2007-05-01 | |
P1433 | published in | Journal of Lipid Research | Q6295449 |
P1476 | title | Influence of major structural features of tocopherols and tocotrienols on their omega-oxidation by tocopherol-omega-hydroxylase | |
P478 | volume | 48 |
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Q46161655 | Activation of autophagy and AMPK by gamma-tocotrienol suppresses the adipogenesis in human adipose derived stem cells |
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Q37289028 | Alpha-tocopherol modulates genes involved in hepatic xenobiotic pathways in mice |
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Q24322624 | CYP4F2 is a vitamin K1 oxidase: An explanation for altered warfarin dose in carriers of the V433M variant |
Q33814811 | Cancer-preventive activities of tocopherols and tocotrienols |
Q43451894 | Chain length of dietary alkylresorcinols affects their in vivo elimination kinetics in rats |
Q24300669 | Common Variants of Cytochrome P450 4F2 Exhibit Altered Vitamin E-Ω-Hydroxylase Specific Activity |
Q46592423 | Comparison of different vehicles to study the effect of tocopherols on gene expression in intestinal cells |
Q28068513 | Complexity of vitamin E metabolism |
Q36573346 | Cytochrome P450 regulation by α-tocopherol in Pxr-null and PXR-humanized mice |
Q80371911 | Cytochrome P450-dependent metabolism of vitamin E isoforms is a critical determinant of their tissue concentrations in rats |
Q34282367 | Deuterium-labeled phylloquinone fed to α-tocopherol-injected rats demonstrates sensitivity of low phylloquinone-containing tissues to menaquinone-4 depletion |
Q36387257 | Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism |
Q36122179 | Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism |
Q46002895 | Effect of bilayer phospholipid composition and curvature on ligand transfer by the alpha-tocopherol transfer protein. |
Q54399979 | Effects of Delta-tocotrienol Supplementation on Liver Enzymes, Inflammation, Oxidative stress and Hepatic Steatosis in Patients with Nonalcoholic Fatty Liver Disease. |
Q36197858 | Enhancement of lipid peroxidation and its amelioration by vitamin E in a subject with mutations in the SBP2 gene |
Q38715276 | Essential Dietary Bioactive Lipids in Neuroinflammatory Diseases |
Q37109910 | Expression of CYP4F2 in human liver and kidney: assessment using targeted peptide antibodies |
Q39871182 | Gamma-tocotrienol and gamma-tocopherol are primarily metabolized to conjugated 2-(beta-carboxyethyl)-6-hydroxy-2,7,8-trimethylchroman and sulfated long-chain carboxychromanols in rats. |
Q36929610 | Human cytochrome p450 family 4 enzymes: function, genetic variation and regulation |
Q34493004 | Increased vitamin E intake is associated with higher alpha-tocopherol concentration in the maternal circulation but higher alpha-carboxyethyl hydroxychroman concentration in the fetal circulation. |
Q27000172 | Intracellular transport of fat-soluble vitamins A and E |
Q37068624 | Long-chain carboxychromanols, metabolites of vitamin E, are potent inhibitors of cyclooxygenases |
Q37076463 | Mechanisms for the prevention of vitamin E excess |
Q48362689 | Metabolic syndrome increases dietary α-tocopherol requirements as assessed using urinary and plasma vitamin E catabolites: a double-blind, crossover clinical trial. |
Q33998131 | Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatory activities and their role in disease prevention and therapy |
Q42084725 | Nonlinear absorption kinetics of self-emulsifying drug delivery systems (SEDDS) containing tocotrienols as lipophilic molecules: in vivo and in vitro studies |
Q36231628 | Novel metabolites and roles for α-tocopherol in humans and mice discovered by mass spectrometry-based metabolomics |
Q34539068 | Nutrigenomics of extra-virgin olive oil: A review. |
Q38078754 | Optimal dosing of warfarin and other coumarin anticoagulants: the role of genetic polymorphisms |
Q59485938 | Phytochemical contents and oxidative stability of oils from non-traditional sources |
Q35639232 | Promotion of plasma membrane repair by vitamin E. |
Q26765469 | Regulation of Obesity and Metabolic Complications by Gamma and Delta Tocotrienols |
Q90656773 | Rifampicin, not vitamin E, suppresses parenteral nutrition-associated liver disease development through the pregnane X receptor pathway in piglets |
Q36580534 | Role of Cytochrome P450 Hydroxylase in the Decreased Accumulation of Vitamin E in Muscle from Turkeys Compared to that from Chickens. |
Q47157084 | Scientific Opinion on Dietary Reference Values for vitamin E as α-tocopherol |
Q37399991 | Sex differences in the inhibition of gamma-tocopherol metabolism by a single dose of dietary sesame oil in healthy subjects. |
Q37682791 | So many options but one choice: the human body prefers alpha-tocopherol. A matter of stereochemistry |
Q30392836 | Structural control of cytochrome P450-catalyzed ω-hydroxylation |
Q53053971 | Structure-Function Relationship Studies In Vitro Reveal Distinct and Specific Effects of Long-Chain Metabolites of Vitamin E. |
Q38742088 | The long chain α-tocopherol metabolite α-13'-COOH and γ-tocotrienol induce P-glycoprotein expression and activity by activation of the pregnane X receptor in the intestinal cell line LS 180. |
Q60934196 | The relationship between vitamin C status, the gut-liver axis, and metabolic syndrome |
Q82284608 | Tissue distribution of α- and γ-tocotrienol and γ-tocopherol in rats and interference with their accumulation by α-tocopherol |
Q51803670 | Tocopherol and annatto tocotrienols distribution in laying-hen body. |
Q36231625 | Urinary α-carboxyethyl hydroxychroman can be used as a predictor of α-tocopherol adequacy, as demonstrated in the Energetics Study |
Q58320258 | Vitamin E |
Q39411586 | Vitamin E and Alzheimer's Disease-Is It Time for Personalized Medicine? |
Q38764248 | Vitamin E and Phosphoinositides Regulate the Intracellular Localization of the Hepatic α-Tocopherol Transfer Protein |
Q89525397 | Vitamin E and cancer prevention: Studies with different forms of tocopherols and tocotrienols |
Q26796303 | Vitamin E function and requirements in relation to PUFA |
Q37618797 | Vitamin E is essential for Purkinje neuron integrity |
Q33939835 | Vitamin E status and metabolism in adult and aged aryl hydrocarbon receptor null mice. |
Q24197764 | Vitamin E supplementation for preventing recurrent stroke and other vascular events in patients with stroke or transient ischaemic attack |
Q24676043 | Vitamin E, antioxidant and nothing more |
Q35648953 | Why tocotrienols work better: insights into the in vitro anti-cancer mechanism of vitamin E. |
Q42549132 | gamma-Tocotrienol ameliorates intestinal radiation injury and reduces vascular oxidative stress after total-body irradiation by an HMG-CoA reductase-dependent mechanism |
Q50968871 | α-Tocopherol does not accelerate depletion of γ-tocopherol and tocotrienol or excretion of their metabolites in rats. |
Q35529243 | α-Tocopherol injections in rats up-regulate hepatic ABC transporters, but not cytochrome P450 enzymes |
Q58800216 | α-Tocopherol transfer protein does not regulate the cellular uptake and intracellular distribution of α- and γ-tocopherols and -tocotrienols in cultured liver cells |
Q36408016 | δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders |
Q37324706 | ω-Hydroxylation of phylloquinone by CYP4F2 is not increased by α-tocopherol. |
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