d-alpha-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties

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d-alpha-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties is …
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scholarly articleQ13442814

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P819ADS bibcode1995PNAS...9212190T
P356DOI10.1073/PNAS.92.26.12190
P932PMC publication ID40322
P698PubMed publication ID8618868
P5875ResearchGate publication ID14581427

P2093author name stringA Azzi
G M Bartoli
D Boscoboinik
P Maroni
A Tasinato
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d-alpha-Tocopherol inhibits low density lipoprotein induced proliferation and protein kinase C activity in vascular smooth muscle cellsQ41553254
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Effect of polyunsaturated fatty acids and antioxidants on lipid peroxidation in tissue cultures.Q41638519
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Fatty acid metabolism and cell proliferation. V. Evaluation of pathways for the generation of lipid peroxidesQ42249101
Bombesin, platelet-derived growth factor, and diacylglycerol induce selective membrane association and down-regulation of protein kinase C isotypes in Swiss 3T3 cellsQ42802413
Okadaic acid-sensitive protein phosphatases dephosphorylate MARCKS, a major protein kinase C substrateQ42803913
Recycling and antioxidant activity of tocopherol homologs of differing hydrocarbon chain lengths in liver microsomesQ43731075
The uptake of (R,R,R)alpha-tocopherol by human endothelial cells in cultureQ44249637
Antioxidant protection of phospholipid bilayers by alpha-tocopherol. Control of alpha-tocopherol status and lipid peroxidation by ascorbic acid and glutathioneQ45012632
Intracellular receptors for activated protein kinase C. Identification of a binding site for the enzymeQ45971419
Fatty acid specificity in the inhibition of cell proliferation and its relationship to lipid peroxidation and prostaglandin biosynthesisQ46672500
Fatty acid metabolism and cell proliferation. VII. Antioxidant effects of tocopherols and their quinonesQ46818208
A phosphatase resistant substrate for the assay of protein kinase C in crude tissue extractsQ48637336
Vitamin E consumption and the risk of coronary disease in women.Q50126258
Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membraneQ59074323
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Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expressionQ67531963
Simultaneous determination of retinol, tocopherols, carotenes and lycopene in plasma by means of high-performance liquid chromatography on reversed phaseQ67864903
Antioxidants stimulate endothelial cell proliferation in cultureQ67992459
The antioxidant butylated hydroxytoluene protects against atherosclerosisQ68183264
Risk of angina pectoris and plasma concentrations of vitamins A, C, and E and caroteneQ68289613
Nascent VLDL from liver perfusions of cynomolgus monkeys are preferentially enriched in RRR- compared with SRR-alpha-tocopherol: studies using deuterated tocopherolsQ68811542
Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase CQ69059319
Calyculin A and okadaic acid: inhibitors of protein phosphatase activityQ69337324
Significance of quiescent smooth muscle migration in the injured rat carotid arteryQ70049140
Decrease in cytosolic calcium/phospholipid-dependent protein kinase activity following phorbol ester treatment of EL4 thymoma cellsQ70515009
Evaluation of myocardial perfusion defects by means of "bull's eye" imagesQ70521365
Inhibition of smooth muscle cell proliferation and protein kinase C activity by tocopherols and tocotrienolsQ72073424
Regulation of the transcription factors NF-kappa B and AP-1 by redox changesQ72459272
Probucol decreases neointimal formation in a swine model of coronary artery balloon injury. A possible role for antioxidants in restenosisQ72852264
P433issue26
P407language of work or nameEnglishQ1860
P304page(s)12190-12194
P577publication date1995-12-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titled-alpha-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties
P478volume92

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