| scholarly article | Q13442814 |
| P50 | author | Hansruedi Glatt | Q37377436 |
| Marc Birringer | Q45846911 | ||
| Paul T Pfluger | Q61820586 | ||
| P2093 | author name string | Regina Brigelius-Flohé | |
| Ralph Rühl | |||
| Dirk Kluth | |||
| Nico Landes | |||
| Gaby-Fleur Böl | |||
| P2860 | cites work | The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions | Q24310512 |
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| Alpha- and gamma-tocotrienols are metabolized to carboxyethyl-hydroxychroman derivatives and excreted in human urine | Q32051277 | ||
| d-alpha-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties | Q33654586 | ||
| P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR. | Q33720425 | ||
| Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells | Q33905168 | ||
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| Tocopherols are metabolized in HepG2 cells by side chain omega-oxidation and consecutive beta-oxidation | Q40794302 | ||
| Quantitative analysis of constitutive and inducible CYPs mRNA expression in the HepG2 cell line using reverse transcription-competitive PCR. | Q40900256 | ||
| alpha-Tocopherol specifically inactivates cellular protein kinase C alpha by changing its phosphorylation state | Q41019160 | ||
| Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E status | Q43984576 | ||
| Dietary sesame seed and its lignans inhibit 2,7,8-trimethyl- 2(2'-carboxyethyl)-6-hydroxychroman excretion into urine of rats fed gamma-tocopherol | Q48618552 | ||
| Novel urinary metabolite of alpha-tocopherol, 2,5,7,8-tetramethyl-2(2'-carboxyethyl)-6-hydroxychroman, as an indicator of an adequate vitamin E supply? | Q53999841 | ||
| Synthetic as compared with natural vitamin E is preferentially excreted as α-CEHC in human urine: studies using deuterated α-tocopheryl acetates | Q58320370 | ||
| Cytochrome P4503A-dependent metabolism of tocopherols and inhibition by sesamin | Q73149364 | ||
| Quantification of the alpha- and gamma-tocopherol metabolites 2,5,7, 8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman and 2,7, 8-trimethyl-2-(2'-carboxyethyl)-6-hydroxychroman in human serum | Q73160343 | ||
| Regulation of rat hepatic hydroxysteroid sulfotransferase (SULT2-40/41) gene expression by glucocorticoids: evidence for a dual mechanism of transcriptional control | Q73201604 | ||
| Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs | Q73450832 | ||
| Vitamin E reduces the uptake of oxidized LDL by inhibiting CD36 scavenger receptor expression in cultured aortic smooth muscle cells | Q73954435 | ||
| alpha-tocopherol inhibits the respiratory burst in human monocytes. Attenuation of p47(phox) membrane translocation and phosphorylation | Q77604560 | ||
| Identities and differences in the metabolism of tocotrienols and tocopherols in HepG2 cells | Q78340427 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | vitamin | Q34956 |
| P304 | page(s) | 269-273 | |
| P577 | publication date | 2003-01-01 | |
| P1433 | published in | Biochemical Pharmacology | Q864229 |
| P1476 | title | Vitamin E activates gene expression via the pregnane X receptor | |
| P478 | volume | 65 |
| Q37470942 | Absorption, transport, and bioavailability of vitamin e and its role in pregnant women. |
| Q34149359 | Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation |
| Q36776690 | Adverse effects of vitamin E by induction of drug metabolism |
| Q37289028 | Alpha-tocopherol modulates genes involved in hepatic xenobiotic pathways in mice |
| Q40331136 | Antagonistic effects of oxidized low density lipoprotein and alpha-tocopherol on CD36 scavenger receptor expression in monocytes: involvement of protein kinase B and peroxisome proliferator-activated receptor-gamma |
| Q35748223 | Anti-atherosclerotic effects of vitamin E--myth or reality? |
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| Q33814811 | Cancer-preventive activities of tocopherols and tocotrienols |
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| Q44480242 | Chemical complementation: small-molecule-based genetic selection in yeast |
| Q27641809 | Coactivator binding promotes the specific interaction between ligand and the pregnane X receptor |
| Q36717800 | Comparative hepatoprotective effects of tocotrienol analogs against drug-induced liver injury |
| Q46592423 | Comparison of different vehicles to study the effect of tocopherols on gene expression in intestinal cells |
| Q28068513 | Complexity of vitamin E metabolism |
| Q27480270 | Comprehensive Analysis of the Effects of Ordinary Nutrients on Hepatitis C Virus RNA Replication in Cell Culture |
| Q35564329 | Cytochrome P450 3A and their regulation |
| Q36573346 | Cytochrome P450 regulation by α-tocopherol in Pxr-null and PXR-humanized mice |
| Q35676529 | Delivery of orally supplemented alpha-tocotrienol to vital organs of rats and tocopherol-transport protein deficient mice. |
| Q47159417 | Dietary reference values for vitamin K |
| Q38648917 | Dietary regulation of adiponectin by direct and indirect lipid activators of nuclear hormone receptors |
| Q38974893 | Drug interactions in HIV treatment: complementary & alternative medicines and over-the-counter products. |
| Q44909192 | Effect of high-dose vitamin C on the steady-state pharmacokinetics of the protease inhibitor indinavir in healthy volunteers |
| Q42121169 | Effects of Trolox on the activity and gene expression of cytochrome P450 in hepatic ischemia/reperfusion |
| Q46880162 | Effects on neural function of repleting vitamin E-deficient rats with alpha-tocopherol |
| Q36440873 | Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds |
| Q36440155 | Functional evolution of the pregnane X receptor |
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| Q90238770 | Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor |
| Q35571310 | Homologous metabolic and gene activating routes for vitamins E and K. |
| Q38178585 | Impact of new-generation lipid emulsions on cellular mechanisms of parenteral nutrition-associated liver disease |
| Q82062094 | Increased antioxidant capacity in the plasma of dogs after a single oral dosage of tocotrienols |
| Q40512385 | Inhibition of HMC-1 mast cell proliferation by vitamin E: involvement of the protein kinase B pathway |
| Q28251165 | Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by delta- and gamma-tocotrienols |
| Q36432268 | Lipophilic micronutrients and adipose tissue biology |
| Q48253329 | Long-Chain Metabolites of Vitamin E: Metabolic Activation as a General Concept for Lipid-Soluble Vitamins? |
| Q89140618 | Mathematical Models in the Description of Pregnane X Receptor (PXR)-Regulated Cytochrome P450 Enzyme Induction |
| Q40966013 | Multi-omic profiles of hepatic metabolism in TPN-fed preterm pigs administered new generation lipid emulsions |
| Q37835926 | Nuclear receptor PXR, transcriptional circuits and metabolic relevance |
| Q38299726 | PCR-verified microarray analysis and functional in vitro studies indicate a role of alpha-tocopherol in vesicular transport |
| Q36551142 | PXR and CAR: nuclear receptors which play a pivotal role in drug disposition and chemical toxicity |
| Q36995453 | PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics |
| Q28748504 | Pregnane X receptor and natural products: beyond drug-drug interactions |
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| Q90656773 | Rifampicin, not vitamin E, suppresses parenteral nutrition-associated liver disease development through the pregnane X receptor pathway in piglets |
| Q36788404 | Role of signalling systems in the effects of dietary factors on the expression of mammalian CYPs |
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| Q37389879 | Serum Metabolomic Response to Long-Term Supplementation with all-rac-α-Tocopheryl Acetate in a Randomized Controlled Trial |
| Q38934814 | TRIENNIAL LACTATION SYMPOSIUM: Nutrigenomics in dairy cows: Nutrients, transcription factors, and techniques. |
| Q36246437 | The Fatty Acid Profile and Oxidative Stability of Meat from Turkeys Fed Diets Enriched with n-3 Polyunsaturated Fatty Acids and Dried Fruit Pomaces as a Source of Polyphenols |
| Q36451492 | The pregnane X receptor in tuberculosis therapeutics |
| Q37400616 | The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism |
| Q40642287 | Tocotrienols induce IKBKAP expression: a possible therapy for familial dysautonomia |
| Q34209443 | Tocotrienols, the vitamin E of the 21st century: its potential against cancer and other chronic diseases |
| Q24678807 | Tocotrienols: Vitamin E beyond tocopherols |
| Q36880038 | Tocotrienols: the emerging face of natural vitamin E |
| Q36285918 | Top Three Pharmacogenomics and Personalized Medicine Applications at the Nexus of Renal Pathophysiology and Cardiovascular Medicine |
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| Q38339490 | Vitamin E activates CRABP-II gene expression in cultured human fibroblasts, role of protein kinase C. |
| Q34650031 | Vitamin E and cancer |
| Q35134282 | Vitamin E and drug metabolism |
| Q35858834 | Vitamin E in New-Generation Lipid Emulsions Protects Against Parenteral Nutrition-Associated Liver Disease in Parenteral Nutrition-Fed Preterm Pigs |
| Q28291248 | Vitamin E in human health and disease |
| Q33939835 | Vitamin E status and metabolism in adult and aged aryl hydrocarbon receptor null mice. |
| Q44631288 | Vitamin E supplementation increases circulating vitamin E metabolites tenfold in end-stage renal disease patients. |
| Q24676043 | Vitamin E, antioxidant and nothing more |
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| Q35988124 | Vitamin E: underestimated as an antioxidant |
| Q35529243 | α-Tocopherol injections in rats up-regulate hepatic ABC transporters, but not cytochrome P450 enzymes |
| Q40974607 | α-Tocopherol long-chain metabolite α-13'-COOH affects the inflammatory response of lipopolysaccharide-activated murine RAW264.7 macrophages |
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