α-Tocopherol long-chain metabolite α-13'-COOH affects the inflammatory response of lipopolysaccharide-activated murine RAW264.7 macrophages

scientific article published on 12 June 2015

α-Tocopherol long-chain metabolite α-13'-COOH affects the inflammatory response of lipopolysaccharide-activated murine RAW264.7 macrophages is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/MNFR.201400737
P698PubMed publication ID25943249
P5875ResearchGate publication ID275887735

P50authorAndreas KoeberleQ30106253
Marta PiroddiQ40255490
Stefan LorkowskiQ41544485
Oliver WerzQ64750706
P2093author name stringMarc Birringer
Michael Glei
Lisa Schmölz
Maria Wallert
Verena Krauth
P2860cites workPhosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activityQ24306142
The relationship between dose of vitamin E and suppression of oxidative stress in humansQ24680423
Gamma (γ) tocopherol upregulates peroxisome proliferator activated receptor (PPAR) gamma (γ) expression in SW 480 human colon cancer cell linesQ24804408
An oxysterol signalling pathway mediated by the nuclear receptor LXR alphaQ28294042
ABCA1 mediates high-affinity uptake of 25-hydroxycholesterol by membrane vesicles and rapid efflux of oxysterol by intact cellsQ28306908
PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathwayQ31793810
Cloning, cellular localization, genomic organization, and tissue-specific expression of the TGFbeta1-inducible SMAP-5 geneQ34422220
Cloning, genomic organization, and tissue-specific expression of the RASL11B gene.Q34650155
gamma-tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cellsQ35307368
Isoforms of Vitamin E Differentially Regulate InflammationQ35734135
Vitamin E mediates cell signaling and regulation of gene expression.Q36064390
Anti-inflammatory effects of alpha-tocopherolQ36064405
Anti-inflammatory properties of alpha- and gamma-tocopherolQ36742854
Modulation of signal transduction by vitamin E.Q36744240
Long-chain carboxychromanols, metabolites of vitamin E, are potent inhibitors of cyclooxygenasesQ37068624
Alpha-tocopherol modulates genes involved in hepatic xenobiotic pathways in miceQ37289028
Isoforms of vitamin E have opposing immunoregulatory functions during inflammation by regulating leukocyte recruitmentQ37358930
Very low density lipoprotein receptor (VLDLR) expression is a determinant factor in adipose tissue inflammation and adipocyte-macrophage interactionQ37488539
Inflammation and atherosclerosis--revisitedQ38157558
Elevated COX2 expression and PGE2 production by downregulation of RXRα in senescent macrophagesQ39094023
Malabaricone C suppresses lipopolysaccharide-induced inflammatory responses via inhibiting ROS-mediated Akt/IKK/NF-κB signaling in murine macrophagesQ39292068
Tocotrienols suppress proinflammatory markers and cyclooxygenase-2 expression in RAW264.7 macrophagesQ39816761
Tocopherols are metabolized in HepG2 cells by side chain omega-oxidation and consecutive beta-oxidationQ40794302
alpha-Tocopherol enrichment of monocytes decreases agonist-induced adhesion to human endothelial cellsQ40993129
Alpha-tocopherol beta-oxidation localized to rat liver mitochondria.Q41872448
Vitamin E activates gene expression via the pregnane X receptorQ44264352
γ‐Tocopherol, but not α‐tocopherol, decreases proinflammatory eicosanoids and inflammation damage in ratsQ44425145
Enhanced inflammatory responses in alpha-tocopherol transfer protein null mice.Q44761613
Anti-inflammatory effects of tocopherol metabolitesQ44926966
RRR-alpha-tocopherol decreases the expression of the major scavenger receptor, CD36, in human macrophages via inhibition of tyrosine kinase (Tyk2).Q44985112
Inhibitory effect of vitamin E on proinflammatory cytokines-and endotoxin-induced nitric oxide release in alveolar macrophagesQ46406148
Inhibition of NF-kappa B activation by vitamin E derivativesQ46571552
Comparison of three tocopherol analogs as an inhibitor of production of proinflammatory mediators in macrophagesQ46946477
High capacity for leukotriene biosynthesis in peripheral blood during pregnancyQ47975816
Vitamin E down-modulates mitogen-activated protein kinases, nuclear factor-kappaB and inflammatory responses in lung epithelial cells.Q53577297
Long-chain metabolites of α-tocopherol occur in human serum and inhibit macrophage foam cell formation in vitro.Q54503330
Proapoptotic effects of long-chain vitamin E metabolites in HepG2 cells are mediated by oxidative stressQ58808968
Constituents of the Seeds of Garcinia kola : Two New Antioxidants, Garcinoic Acid and GarcinalQ105094913
P433issue8
P921main subjectlipopolysaccharideQ421804
P304page(s)1524-1534
P577publication date2015-06-12
P1433published inMolecular Nutrition and Food ResearchQ15751861
P1476titleα-Tocopherol long-chain metabolite α-13'-COOH affects the inflammatory response of lipopolysaccharide-activated murine RAW264.7 macrophages
P478volume59

Reverse relations

cites work (P2860)
Q36197881Analysis of vitamin E metabolites including carboxychromanols and sulfated derivatives using LC/MS/MS.
Q28068513Complexity of vitamin E metabolism
Q94560863Diversity of Chromanol and Chromenol Structures and Functions: An Emerging Class of Anti-Inflammatory and Anti-Carcinogenic Agents
Q64096857In Vitro Digested Nut Oils Attenuate the Lipopolysaccharide-Induced Inflammatory Response in Macrophages
Q48253329Long-Chain Metabolites of Vitamin E: Metabolic Activation as a General Concept for Lipid-Soluble Vitamins?
Q34539068Nutrigenomics of extra-virgin olive oil: A review.
Q53053971Structure-Function Relationship Studies In Vitro Reveal Distinct and Specific Effects of Long-Chain Metabolites of Vitamin E.
Q64105348The vitamin E derivative garcinoic acid from Garcinia kola nut seeds attenuates the inflammatory response

Search more.