Effect of Vitamin E on Glutathione-Dependent Enzymes

scientific article (publication date: 2003)

Effect of Vitamin E on Glutathione-Dependent Enzymes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1081/DMR-120024086
P698PubMed publication ID12959415

P50authorAalt BastQ15868353
Chris T. EveloQ19845641
P2093author name stringGuido R. M. M. Haenen
Rachel I. M. van Haaften
P2860cites workA novel human tocopherol-associated protein: cloning, in vitro expression, and characterizationQ22254156
Zeta, a novel class of glutathione transferases in a range of species from plants to humansQ24312844
Regulation of JNK signaling by GSTpQ24533822
Common structural features of MAPEG -- a widespread superfamily of membrane associated proteins with highly divergent functions in eicosanoid and glutathione metabolismQ24672755
Identification, characterization, and crystal structure of the Omega class glutathione transferasesQ27622324
Vitamin E: function and metabolismQ28138332
Molecular aspects of alpha-tocotrienol antioxidant action and cell signallingQ28143041
Tocotrienol: a review of its therapeutic potentialQ28144102
Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG). A widespread protein superfamilyQ28144672
Hypocholesterolemic activity of synthetic and natural tocotrienolsQ28202438
Dose-dependent suppression of serum cholesterol by tocotrienol-rich fraction (TRF25) of rice bran in hypercholesterolemic humansQ28205496
Regulation of expression of the multidrug resistance-associated protein 2 (MRP2) and its role in drug dispositionQ28215470
Regulation of cellular glutathioneQ28257873
Gamma-tocopheryl quinone stimulates apoptosis in drug-sensitive and multidrug-resistant cancer cellsQ43927546
Regulation of microsomal and cytosolic glutathione S-transferase activities by S-nitrosylationQ43983989
Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E statusQ43984576
The oligomeric structure of rat liver microsomal glutathione transferase studied by chemical cross-linkingQ44127022
Activation of microsomal glutathione s-transferase by peroxynitriteQ44253625
Activation of the microsomal glutathione-S-transferase and reduction of the glutathione dependent protection against lipid peroxidation by acroleinQ44707919
Fatty acid metabolism and cell proliferation. VII. Antioxidant effects of tocopherols and their quinonesQ46818208
The widely used anesthetic agent propofol can replace alpha-tocopherol as an antioxidant.Q51612837
Reactions of vitamin E and its model compound 2,2,5,7,8-pentamethylchroman-6-ol with ozone.Q54053667
Oxidation of the α-tocopherol model compound 2,2,5,7,8-pentamethyl-6-chromanol in the presence of alcohols.Q54235842
On the Constitution of α-TocopherolQ56092267
Mechanism of Interaction of Vitamin E and Glutathione in the Protection against Membrane Lipid PeroxidationQ56113363
Transcriptional Regulation of γ-Glutamylcysteine Synthetase-Heavy Subunit by Oxidants in Human Alveolar Epithelial CellsQ58317042
Glutathione-dependent factors and inhibition of rat liver microsomal lipid peroxidationQ73695225
Inhibitors of glutathione S-transferases as therapeutic agentsQ73850202
Glutathione S-transferases and prevention of cellular free radical damageQ77295990
Modulation of alpha-tropomyosin expression by alpha-tocopherol in rat vascular smooth muscle cellsQ77369968
Vitamin E and atherosclerosisQ77409463
Binding of alpha-tocopherylquinone, an oxidized form of alpha-tocopherol, to glutathione-S-transferase in the liver cytosolQ77508155
Comparative study on dynamics of antioxidative action of alpha-tocopheryl hydroquinone, ubiquinol, and alpha-tocopherol against lipid peroxidationQ78195063
Identities and differences in the metabolism of tocotrienols and tocopherols in HepG2 cellsQ78340427
Dietary alpha-tocopherol attenuates the impact of gamma-tocotrienol on hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in chickensQ28279072
The chemistry and antioxidant properties of tocopherols and tocotrienolsQ28291396
Is α-tocopherol a reservoir for α-tocopheryl hydroquinone?Q28295837
Identification of a putative antioxidant response element in the 5'-flanking region of the human gamma-glutamylcysteine synthetase heavy subunit geneQ28300319
The glutathione S-transferases in selenium and vitamin E deficiencyQ28362542
Antioxidant functions of vitamins. Vitamins E and C, beta-carotene, and other carotenoidsQ28609442
Tocotrienols Inhibit Human Glutathione S-Transferase P1-1Q28861104
The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistanceQ29616511
Excess dietary vitamin E lowers the activities of antioxidative enzymes in erythrocytes of rats fed salmon oil.Q30320754
The multidrug resistance protein family.Q30323786
Identification of a novel cytosolic tocopherol-binding protein: structure, specificity, and tissue distribution.Q30326758
Gamma glutamyl transferaseQ31010652
alpha-Tocopherol inhibits human glutathione S-transferase pi.Q31855550
d-alpha-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant propertiesQ33654586
Concise review of the glutathione S-transferases and their significance to toxicologyQ33693265
Molecular mechanisms of vitamin E transport.Q33711813
Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress.Q33750086
Intracellular antioxidants: from chemical to biochemical mechanismsQ33763063
Gene expression and the thiol redox stateQ33777925
Regulation of gamma-glutamylcysteine synthetase subunit gene expression: insights into transcriptional control of antioxidant defensesQ33878163
Vitamin E and its function in membranesQ33900377
Vitamin E: non-antioxidant rolesQ33900909
The antioxidant paradoxQ33903881
Glutathione: interorgan translocation, turnover, and metabolismQ33979283
Persuasive evidence that quinone reductase type 1 (DT diaphorase) protects cells against the toxicity of electrophiles and reactive forms of oxygenQ34062692
The location and function of vitamin E in membranes (review).Q34112768
Nonantioxidant functions of alpha-tocopherol in smooth muscle cellsQ34131829
Mechanisms of vitamin E regulation: research over the past decade and focus on the futureQ34168979
Diverse functions of antioxidantsQ34173961
Biokinetics in humans of RRR-alpha-tocopherol: the free phenol, acetate ester, and succinate ester forms of vitamin E.Q34368058
Non-antioxidant molecular functions of alpha-tocopherol (vitamin E).Q34649000
The 80th anniversary of vitamin E: beyond its antioxidant propertiesQ34658905
Cellular glutathione and thiols metabolism.Q34816421
Glutathione catabolism as a signaling mechanismQ34816445
Cell signalling and the glutathione redox systemQ34816510
The European perspective on vitamin E: current knowledge and future researchQ34905197
Mutagenicity of tocopheryl quinones: evolutionary advantage of selective accumulation of dietary alpha-tocopherolQ35017483
Glutathione conjugates and their synthetic derivatives as inhibitors of glutathione-dependent enzymes involved in cancer and drug resistanceQ35027940
Treatment of Atherosclerosis in the New Millennium: Is There a Role for Vitamin E?Q35122105
Does Vitamin E Supplementation Prevent Cardiovascular Events?Q35125378
Redox cycling of iron and lipid peroxidation.Q35232989
Erythrocyte glutathione S transferase as a marker of oxidative stress at birthQ35288682
gamma-tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cellsQ35307368
Tolerance and safety of vitamin E: A toxicological position reportQ36313257
The role of glutathione-dependent enzymes in drug resistanceQ36540883
Absorption, transport and metabolism of vitamin E.Q37253869
Oxidants and antioxidants: state of the art.Q37413730
A new endogenous natriuretic factor: LLU-alphaQ37567918
Absorption, transport and distribution of vitamin E.Q37910501
Vitamin E: antioxidant activity, biokinetics, and bioavailabilityQ37946519
Characterization of cysteine residues of glutathione S-transferase P: evidence for steric hindrance of substrate binding by a bulky adduct to cysteine 47Q38325168
Friedreich's ataxia with isolated vitamin E deficiency: a neuropathological study of a Tunisian patientQ39160969
Glutathione peroxidaseQ39576914
The tocopherol content of food and influencing factorsQ39712296
The GlutathioneS-Transferases: A Group of Multifunctional Detoxification ProteinsQ39719839
The isoenzymes of glutathione transferaseQ39828869
Mechanisms of lipid peroxidationQ39843060
Vitamin E: beyond antioxidant functionQ40380204
Role of renal metabolism in risk to toxic chemicalsQ40517484
Human glutathione S-transferasesQ40755010
d-alpha-tocopherol control of cell proliferationQ40792186
Tocopherols are metabolized in HepG2 cells by side chain omega-oxidation and consecutive beta-oxidationQ40794302
The role of metabolism in the antioxidant function of vitamin E.Q40824354
A novel 5'-carboxychroman metabolite of gamma-tocopherol secreted by HepG2 cells and excreted in human urineQ40895020
Vitamin E mediated response of smooth muscle cell to oxidant stress.Q40913829
How to characterize an antioxidant: an updateQ41004333
Long exposure to high glucose concentration impairs the responsive expression of gamma-glutamylcysteine synthetase by interleukin-1beta and tumor necrosis factor-alpha in mouse endothelial cells.Q41190896
Products of gamma-tocopherol reaction with NO2 and their formation in rat insulinoma (RINm5F) cellsQ41305625
Antioxidant and cytotoxic tocopheryl quinones in normal and cancer cellsQ41340547
Polyunsaturated fatty acids, vitamine E, and the proliferation of aortic smooth muscle cellsQ41459595
Activation of microsomal glutathione S-transferase activity by sulfhydryl reagentsQ41668035
Excretion of GSSG and glutathione conjugates mediated by MRP1 and cMOAT/MRP2.Q42537054
Inhibition of glutathione conjugation in the rat in vivo by analogues of glutathione conjugatesQ42540832
Interactions of alpha, beta-unsaturated aldehydes and ketones with human glutathione S-transferase P1-1.Q42545089
Nomenclature for human glutathione transferasesQ42793315
No reduction of alpha-tocopherol quinone by glutathione in rat liver microsomesQ43552490
Structural and functional consequences of inactivation of human glutathione S-transferase P1-1 mediated by the catechol metabolite of equine estrogens, 4-hydroxyequilenin.Q43569395
Reduction of alpha-tocopherolquinone to alpha-tocopherolhydroquinone in rat hepatocytesQ43585880
New synthesis of (+/-)-alpha-CMBHC and its confirmation as a metabolite of alpha-tocopherol (vitamin E).Q43620443
Oxidative catabolism of alpha-tocopherol in rat liver microsomesQ43624499
Pro-oxidant effect of vitamin E in cigarette smokers consuming a high polyunsaturated fat dietQ43633712
Inhibition of human glutathione S-transferase P1-1 by tocopherols and alpha-tocopherol derivativesQ43672583
Vitamin E kinetics in smokers and nonsmokersQ43812529
Effects of vitamin E and HMG-CoA reductase inhibition on cholesteryl ester transfer protein and lecithin-cholesterol acyltransferase in hypercholesterolemiaQ58863685
Identification and quantitation of glutathione in hepatic protein mixed disulfides and its relationship to glutathione disulfideQ59151806
The induction of GSH synthesis by nanomolar concentrations of NO in endothelial cells: a role for γ-glutamylcysteine synthetase and γ-glutamyl transpeptidaseQ61866580
Flavonoids can replace α-tocopherol as an antioxidantQ61959399
Protection against lipid peroxidation by a microsomal glutathione-dependent labile factorQ61959440
The Redox Pair Vitamin E and Vitamin C, A13C-NMR StudyQ62512150
Vitamin E dependent reduced glutathione inhibition of rat liver microsomal lipid peroxidation.Q64924489
Increased cytogenetic damage in smokers deficient in glutathione S-transferase isozyme μQ67753826
Purification and characterization of the alpha-tocopherol transfer protein from rat liverQ67956849
Vitamin E, membrane order, and antioxidant behavior in lung microsomes and reconstituted lipid vesiclesQ67963721
Modulation of class Pi glutathione transferase activity by sulfhydryl group modificationQ67981329
4-Hydroxy-2,3-trans-nonenal stimulates microsomal lipid peroxidation by reducing the glutathione-dependent protectionQ68530292
Vitamin E and glutathione are required for preservation of microsomal glutathione S-transferase from oxidative stress in microsomesQ68855599
Effect of thiols on lipid peroxidation in rat liver microsomesQ69405029
Reduced glutathione effects on alpha-tocopherol concentration of rat liver microsomes undergoing NADPH-dependent lipid peroxidationQ69431268
Evidence that alpha-tocopherol functions cyclically to quench free radicals in hepatic microsomes. Requirement for glutathione and a heat-labile factorQ69455122
Friedreich's disease: V. Variant form with vitamin E deficiency and normal fat absorptionQ69703003
Isolated deficiency of vitamin E with progressive neurologic deteriorationQ69762145
Purification from pig liver of a protein which protects liposomes and biomembranes from peroxidative degradation and exhibits glutathione peroxidase activity on phosphatidylcholine hydroperoxidesQ70305491
The distribution of microsomal glutathione transferase among different organelles, different organs, and different organismsQ70509684
Oxidative stress-induced activation of microsomal glutathione S-transferase in isolated rat liverQ70540221
A progressive neurological syndrome associated with an isolated vitamin E deficiencyQ70704945
Identification of a hepatic plasma membrane glutathione S-transferase activated by N-ethylmaleimideQ70731320
Glutathione S-transferase (transferase π) from human placenta is identical or closely related to glutathione S-transferase (transferase ϱ) from erythrocytesQ70968101
Response of hypercholesterolemic subjects to administration of tocotrienolsQ71040895
Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)Q71060539
The glutathione peroxidase activity of glutathione S-transferasesQ71128842
Increased glutathione-S-transferase activity in antioxidant-deficient ratsQ71290354
Up-regulation of glutathione synthesis in rat kidney by methyl mercury. Relationship to mercury-induced oxidative stressQ71598899
Glutathione-dependent protection by rat liver microsomal protein against lipid peroxidationQ71702503
On the formation and measurement of alpha-tocopherolquinone and alpha-tocopherolhydroquinone in rat tissuesQ71715420
The influence of phospholipase A2 and glutathione peroxidase on the elimination of membrane lipid peroxidesQ71758040
Nitric oxide-induced oxidation of alpha-tocopherolQ71808662
The regulatory function of vitamine EQ71935250
Glutathione metabolism by gamma-glutamyltranspeptidase leads to lipid peroxidation: characterization of the system and relevance to hepatocarcinogenesisQ72211020
Inhibitors of cholesterol biosynthesis. 2. Hypocholesterolemic and antioxidant activities of benzopyran and tetrahydronaphthalene analogues of the tocotrienolsQ72275033
Vitamin EQ72414750
Glutathione S-transferase and gamma-glutamyl transpeptidase activities in cultured rat hepatocytes treated with tocotrienol and tocopherolQ72661765
The oxidation of alpha-tocopherol and trolox by peroxynitriteQ72764911
Prooxidant role of vitamin E in copper induced lipid peroxidationQ72911915
Antioxidant reactions of alpha-tocopherolhydroquinoneQ73065155
alpha-Tocopheryl quinone is converted into vitamin E in manQ73268947
Vitamin E supplementation and cardiovascular events in high-risk patientsQ73365511
Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogsQ73450832
The reduction of alpha-tocopherolquinone by human NAD(P)H: quinone oxidoreductase: the role of alpha-tocopherolhydroquinone as a cellular antioxidantQ73626779
P433issue2-3
P407language of work or nameEnglishQ1860
P921main subjectvitaminQ34956
P1104number of pages39
P304page(s)215-253
P577publication date2003-01-01
P1433published inDrug Metabolism ReviewsQ5308857
P1476titleEffect of Vitamin E on Glutathione-Dependent Enzymes
P478volume35

Reverse relations

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