scholarly article | Q13442814 |
P2093 | author name string | C J Henderson | |
C R Wolf | |||
K D Tew | |||
Z Ronai | |||
R J Davis | |||
V Adler | |||
Z Yin | |||
M R Pincus | |||
M Benezra | |||
M Sardana | |||
S Y Fuchs | |||
L Rosario | |||
P2860 | cites work | JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension | Q22007973 |
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension | Q24307473 | ||
A model for p53-induced apoptosis | Q24313374 | ||
Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme | Q24555669 | ||
The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase | Q24561826 | ||
Expression cloning of a human dual-specificity phosphatase | Q24562377 | ||
Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase | Q24655723 | ||
c-Jun NH2-terminal kinases target the ubiquitination of their associated transcription factors | Q28257088 | ||
Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development | Q28268881 | ||
A mammalian scaffold complex that selectively mediates MAP kinase activation | Q28281953 | ||
Transcription factor ATF2 regulation by the JNK signal transduction pathway | Q28305631 | ||
Phosphorylation-dependent targeting of c-Jun ubiquitination by Jun N-kinase | Q28567939 | ||
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis | Q29547567 | ||
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway | Q29614258 | ||
Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain | Q29614381 | ||
The stress-activated protein kinase subfamily of c-Jun kinases | Q29620001 | ||
Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK | Q29620274 | ||
Complexes of p21RAS with JUN N-terminal kinase and JUN proteins | Q33786380 | ||
Selective suppression of stress-activated protein kinase pathway by protein phosphatase 2C in mammalian cells | Q34480909 | ||
Autocrine growth and anchorage independence: two complementing Jun-controlled genetic programs of cellular transformation. | Q35196825 | ||
JNK targets p53 ubiquitination and degradation in nonstressed cells | Q35208651 | ||
Conformation-dependent phosphorylation of p53. | Q36019930 | ||
Increased skin tumorigenesis in mice lacking pi class glutathione S-transferases | Q36068630 | ||
Arachidonic acid activates c-jun N-terminal kinase through NADPH oxidase in rabbit proximal tubular epithelial cells | Q36105342 | ||
Activation of protein kinase C by tyrosine phosphorylation in response to H2O2. | Q36590164 | ||
Phorbol esters stimulate the phosphorylation of c-Jun but not v-Jun: regulation by the N-terminal delta domain | Q37055760 | ||
MEKK1/JNK signaling stabilizes and activates p53. | Q37474256 | ||
UV irradiation and heat shock mediate JNK activation via alternate pathways. | Q38289506 | ||
Glutathione transferases as markers of preneoplasia and neoplasia | Q38655792 | ||
The GlutathioneS-Transferases: A Group of Multifunctional Detoxification Proteins | Q39719839 | ||
The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents | Q40023085 | ||
Glutathione-associated enzymes in anticancer drug resistance. | Q40680199 | ||
Stress-induced secretion of growth inhibitors: a novel tumor suppressor function of p53. | Q41004423 | ||
A non-enzymatic p21 protein inhibitor of stress-activated protein kinases | Q41190478 | ||
Impaired jun-NH2-terminal kinase activation by ultraviolet irradiation in fibroblasts of patients with Cockayne syndrome complementation group B. | Q41194461 | ||
MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases? | Q41345475 | ||
v-Src and EJ Ras alleviate repression of c-Jun by a cell-specific inhibitor | Q41675040 | ||
Glutathione-S-transferase pi as a determinant of drug resistance in transfectant cell lines | Q41740289 | ||
Oxygen radicals and signaling | Q41750986 | ||
Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases | Q42804655 | ||
Activation of c-Jun-NH2-kinase by UV irradiation is dependent on p21ras | Q42808831 | ||
Involvement of glutathione in induction of c-jun proto-oncogene by methylmethanesulfonate in NIH 3T3 cells | Q42814860 | ||
Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury | Q42816281 | ||
jun-NH2-terminal kinase activation mediated by UV-induced DNA lesions in melanoma and fibroblast cells. | Q42822966 | ||
DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1. | Q46784718 | ||
An osmosensing signal transduction pathway in mammalian cells | Q48080102 | ||
Immunohistochemical localization of glutathione S-transferases α μ and π in normal tissue and carcinomas from human colon | Q53495172 | ||
Isozyme specificity of novel glutathione-S-transferase inhibitors. | Q54253506 | ||
Integration of MAP kinase signal transduction pathways at the serum response element | Q58415341 | ||
Enzymatic conjugation of chlorambucil with glutathione by human glutathione S-transferases and inhibition by ethacrynic acid | Q68028183 | ||
Identification of cysteine residues involved in disulfide formation in the inactivation of glutathione transferase P-form by hydrogen peroxide | Q70539826 | ||
Reactive oxygen species mediate cytokine activation of c-Jun NH2-terminal kinases | Q71143796 | ||
JNK (c-Jun NH2-terminal kinase) is a target for antioxidants in T lymphocytes | Q71574085 | ||
Tumor necrosis factor alpha stimulates AP-1 activity through prolonged activation of the c-Jun kinase | Q72724630 | ||
Stress-activated kinases regulate protein stability | Q77436414 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1321-34 | |
P577 | publication date | 1999-03-01 | |
P1433 | published in | The EMBO Journal | Q1278554 |
P1476 | title | Regulation of JNK signaling by GSTp | |
P478 | volume | 18 |
Q40037259 | 4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas. |
Q47718656 | 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio) hexanol: a promising new anticancer compound |
Q40423799 | 7-Nitro-2,1,3-benzoxadiazole derivatives, a new class of suicide inhibitors for glutathione S-transferases. Mechanism of action of potential anticancer drugs |
Q35868973 | A Study of the Wound Healing Mechanism of a Traditional Chinese Medicine, Angelica sinensis, Using a Proteomic Approach |
Q39570737 | A bifunctional organometallic ruthenium drug with multiple modes of inducing apoptosis |
Q35551957 | A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts |
Q40268754 | A strong glutathione S-transferase inhibitor overcomes the P-glycoprotein-mediated resistance in tumor cells. 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) triggers a caspase-dependent apoptosis in MDR1-expressing leukemia cells. |
Q92916618 | A structure-based mechanism of cisplatin resistance mediated by glutathione transferase P1-1 |
Q28578935 | Acrolein activates mitogen-activated protein kinase signal transduction pathways in rat vascular smooth muscle cells |
Q46751514 | Activation of C-Jun N-terminal kinase is required for glutathione transferase A4 induction during oxidative stress, not during cell proliferation, in mouse hepatocytes |
Q43505476 | Activation of JNK, p38 and ERK mitogen-activated protein kinases by chromium(VI) is mediated through oxidative stress but does not affect cytotoxicity |
Q39369941 | Activation of c-Jun NH(2)-terminal kinase is required for porcine reproductive and respiratory syndrome virus-induced apoptosis but not for virus replication |
Q37167897 | Activation of c-Jun-N-terminal kinase and decline of mitochondrial pyruvate dehydrogenase activity during brain aging |
Q44036971 | Activation of the p38 signaling pathway by heat shock involves the dissociation of glutathione S-transferase Mu from Ask1. |
Q92941172 | Affinity Isolation and Mass Spectrometry Identification of Prostacyclin Synthase (PTGIS) Subinteractome |
Q36748625 | Ageing to arrhythmias: conundrums of connections in the ageing heart |
Q36396542 | Altered DNA binding and amplification of human breast cancer suppressor gene BRCA1 induced by a novel antitumor compound, [Ru(η(6)-p-phenylethacrynate)Cl(2)(pta)]. |
Q40602969 | Altered protein S-glutathionylation identifies a potential mechanism of resistance to acetaminophen-induced hepatotoxicity. |
Q24309271 | Alternative mutations of a positively selected residue elicit gain or loss of functionalities in enzyme evolution |
Q36363144 | Alternative splicing of glutathione S-transferases |
Q42803661 | Amino-terminal-derived JNK fragment alters expression and activity of c-Jun, ATF2, and p53 and increases H2O2-induced cell death |
Q44938827 | An effector peptide from glutathione-S-transferase-pi strongly and selectively blocks mitotic signaling by oncogenic ras-p21. |
Q35155844 | Analysis of glutathione: implication in redox and detoxification |
Q28387384 | Antiapoptotic effects of EGb 761 |
Q35544819 | Antioxidant enzymes in blood of patients with Friedreich's ataxia. |
Q40706938 | Antioxidant status and GST gene polymorphisms in antitubercular treatment-induced hepatotoxicity patients |
Q82860891 | Aplidin induces JNK-dependent apoptosis in human breast cancer cells via alteration of glutathione homeostasis, Rac1 GTPase activation, and MKP-1 phosphatase downregulation |
Q40552078 | Arsenic transport by the human multidrug resistance protein 1 (MRP1/ABCC1). Evidence that a tri-glutathione conjugate is required |
Q64963322 | Assessment of the XPC (A2920C), XPF (T30028C), TP53 (Arg72Pro) and GSTP1 (Ile105Val) polymorphisms in the risk of cutaneous melanoma. |
Q42233705 | Association between long-term neuro-toxicities in testicular cancer survivors and polymorphisms in glutathione-s-transferase-P1 and -M1, a retrospective cross sectional study |
Q48299300 | Association of A313 G polymorphism (GSTP1*B) in the glutathione-S-transferase P1 gene with sporadic Parkinson's disease |
Q41693491 | Association of glutathione S-transferase pi (GSTP1) Ile105Val polymorphism with the risk of skin cancer: a meta-analysis |
Q37041521 | Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π. |
Q24530084 | Biochemical and genetic characterization of a murine class Kappa glutathione S-transferase |
Q37404738 | Biological properties of garlic and garlic-derived organosulfur compounds |
Q38357424 | Biotransformation of xenobiotics in the human colon and rectum and its association with colorectal cancer |
Q39747683 | Bisphenol A-Induced Ovotoxicity Involves DNA Damage Induction to Which the Ovary Mounts a Protective Response Indicated by Increased Expression of Proteins Involved in DNA Repair and Xenobiotic Biotransformation |
Q34816510 | Cell signalling and the glutathione redox system |
Q59100682 | Characterization of affinity-purified isoforms of Acinetobacter calcoaceticus Y1 glutathione transferases |
Q44210370 | Characterization of an omega-class glutathione S-transferase from Schistosoma mansoni with glutaredoxin-like dehydroascorbate reductase and thiol transferase activities |
Q40626678 | Characterization of cell death induced by ethacrynic acid in a human colon cancer cell line DLD‐1 and suppression by N‐acetyl‐l‐cysteine |
Q41825511 | Characterization of the complex of glutathione S-transferase pi and 1-cysteine peroxiredoxin |
Q31119257 | Characterization of the molecular forms of glutathione S-transferase P1 in human gastric cancer cells (Kato III) and in normal human erythrocytes |
Q50994157 | Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment. |
Q35356809 | Cocaine-induced adaptations in cellular redox balance contributes to enduring behavioral plasticity |
Q37973280 | Combination strategies in myelodysplastic syndromes. |
Q36097289 | Combined GSTM1-Null, GSTT1-Active, GSTA1 Low-Activity and GSTP1-Variant Genotype Is Associated with Increased Risk of Clear Cell Renal Cell Carcinoma |
Q40401556 | Combined effects of GSTP1 and MRP1 in melanoma drug resistance |
Q34195208 | Comparative proteome analysis of human lung squamous carcinoma using two different methods: two-dimensional gel electrophoresis and iTRAQ analysis |
Q39307013 | Concordance of genotype for polymorphisms in DNA isolated from peripheral blood and colorectal cancer tumor samples |
Q37154905 | Coniferyl Ferulate, a Strong Inhibitor of Glutathione S-Transferase Isolated from Radix Angelicae sinensis, Reverses Multidrug Resistance and Downregulates P-Glycoprotein |
Q24303657 | Constitutive c-jun N-terminal kinase activity in acute myeloid leukemia derives from Flt3 and affects survival and proliferation |
Q53478244 | Copper-Induced Inactivation of Camel Liver Glutathione S-Transferase. |
Q27670672 | Crystal structures and kinetic studies of human Kappa class glutathione transferase provide insights into the catalytic mechanism |
Q44741231 | Curcumin-induced apoptosis in scleroderma lung fibroblasts: role of protein kinase cepsilon. |
Q38241806 | Cytoprotective and regulatory functions of glutathione S-transferases in cancer cell proliferation and cell death |
Q45049803 | DLJ14, a novel chemo-sensitization agent, enhances therapeutic effects of adriamycin against MCF-7/A cells both in vitro and in vivo |
Q38786434 | Design and synthesis of 2-substituted-5-(4-trifluoromethylphenyl-sulphonamido)benzoxazole derivatives as human GST P1-1 inhibitors |
Q50923082 | Designer xanthone: an inhibitor scaffold for MDR-involved human glutathione transferase isoenzyme A1-1. |
Q36603481 | Determination of oxidative stress and activities of antioxidant enzymes in guinea pigs treated with haloperidol. |
Q42381186 | Detoxifying Enzymes at the Cross-Roads of Inflammation, Oxidative Stress, and Drug Hypersensitivity: Role of Glutathione Transferase P1-1 and Aldose Reductase |
Q40379195 | Development of a transactivator in hepatoma cells that allows expression of phase I, phase II, and chemical defense genes. |
Q28577529 | Development of glutathione S-transferase-P-negative foci accompanying nuclear factor-erythroid 2-related factor 2 expression during early stage of rat hepatocarcinogenesis |
Q43565023 | Developmental expression and distribution of amphibian glutathione transferases |
Q33200019 | Differential roles of tau class glutathione S-transferases in oxidative stress |
Q40553546 | Differentiation induction of human keratinocytes by phosphatidylethanolamine-binding protein |
Q39988480 | Dipyrithione inhibits lipopolysaccharide-induced iNOS and COX-2 up-regulation in macrophages and protects against endotoxic shock in mice |
Q36376476 | Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: selective regulation of mitogen-activated protein kinase activation and fas ligand expression |
Q36363149 | Disruption of the glutathione transferase pi class genes. |
Q44026911 | Distinct roles for glutathione S-transferases in the oxidative stress response in Schizosaccharomyces pombe |
Q36253003 | Disulfide relays and phosphorylative cascades: partners in redox-mediated signaling pathways |
Q36731149 | Does oxidative stress participate in the development of hepatocellular carcinoma? |
Q35019567 | Dose effect of oxidative stress on signal transduction in aging |
Q43583359 | Down-regulation of the c-Jun N-terminal kinase (JNK) phosphatase M3/6 and activation of JNK by hydrogen peroxide and pyrrolidine dithiocarbamate |
Q57302790 | Drug metabolism and drug toxicity |
Q38959826 | Dual glutathione-S-transferase-θ1 and -μ1 gene deletions determine imatinib failure in chronic myeloid leukemia |
Q34078524 | Dual protective role for glutathione S-transferase class pi against VCD-induced ovotoxicity in the rat ovary |
Q42816065 | Dual-specificity protein tyrosine phosphatase VHR down-regulates c-Jun N-terminal kinase (JNK). |
Q40514002 | Dynamic evolution of the adenine nucleotide translocase interactome during chemotherapy-induced apoptosis |
Q27987364 | Effect of Vitamin E on Glutathione-Dependent Enzymes |
Q38963762 | Effect of a glutathione S-transferase inhibitor on oxidative stress and ischemia-reperfusion-induced apoptotic signalling of cultured cardiomyocytes |
Q36568958 | Effects of Ginger Phenylpropanoids and Quercetin on Nrf2-ARE Pathway in Human BJ Fibroblasts and HaCaT Keratinocytes |
Q39340258 | Effects of geranyl-phloroacetophenone on the induction of apoptosis and chemosensitization of adriamycin-resistant MCF-7 human breast cancer cells. |
Q44008179 | Efficacy of HOCl scavenging by sulfur-containing compounds: antioxidant activity of glutathione disulfide? |
Q44248610 | Efficacy of a glutathione S-transferase pi-activated prodrug in platinum-resistant ovarian cancer cells |
Q34627846 | Efficacy of venlafaxine for the prevention and relief of oxaliplatin-induced acute neurotoxicity: results of EFFOX, a randomized, double-blind, placebo-controlled phase III trial. |
Q38828060 | Energy metabolism and inflammation in brain aging and Alzheimer's disease. |
Q33605331 | Environmental factors as regulators and effectors of multistep carcinogenesis |
Q57570317 | Epigenetic Mechanisms in Cancer Formation and Progression |
Q28830795 | Erythrocyte glutathione transferase: a general probe for chemical contaminations in mammals |
Q36211438 | Erythrocyte glutathione transferase: a new biomarker for hemodialysis adequacy, overcoming the Kt/V(urea) dogma? |
Q33611227 | Estrogen inhibits starvation-induced apoptosis in osteocytes by a redox-independent process involving association of JNK and glutathione S-transferase P1-1. |
Q39256481 | Ethacrynic acid and a derivative enhance apoptosis in arsenic trioxide-treated myeloid leukemia and lymphoma cells: the role of glutathione S-transferase p1-1. |
Q59034916 | Evaluation of Platinum-Ethacrynic Acid Conjugates in the Treatment of Mesothelioma |
Q44699812 | Evaluation of the in vitro inhibitory impact of hypericin on placental glutathione S-transferase pi. |
Q33639120 | Exercise and Glycemic Control: Focus on Redox Homeostasis and Redox-Sensitive Protein Signaling |
Q44462253 | Exploration of in vitro pro-drug activation and futile cycling by glutathione S-transferases: thiol ester hydrolysis and inhibitor maturation |
Q73954951 | Expression of hGSTP1 alleles in human lung and catalytic activity of the native protein variants towards 1-chloro-2,4-dinitrobenzene, 4-vinylpyridine and (+)-anti benzo[a]pyrene-7,8-diol-9,10-oxide |
Q34131334 | Expression of mutant human cystathionine beta-synthase rescues neonatal lethality but not homocystinuria in a mouse model |
Q36961192 | Expression of ovarian microsomal epoxide hydrolase and glutathione S-transferase during onset of VCD-induced ovotoxicity in B6C3F(1) mice |
Q38300595 | Expression, purification and functional analysis of hexahistidine-tagged human glutathione S-transferase P1-1 and its cysteinyl mutants |
Q38365967 | Ezatiostat hydrochloride for the treatment of myelodysplastic syndromes |
Q28204361 | Fanconi anemia group C protein prevents apoptosis in hematopoietic cells through redox regulation of GSTP1 |
Q28281453 | Flavonoids: modulators of brain function? |
Q40000787 | Fluoxetine-induced toxicity results in human placental glutathione S-transferase-π (GST-π) dysfunction |
Q28468284 | Formation and Biological Targets of Quinones: Cytotoxic versus Cytoprotective Effects |
Q47381575 | GFZF, a glutathione S-transferase protein implicated in cell cycle regulation and hybrid inviability, is a transcriptional co-activator |
Q41764430 | GST pi modulates JNK activity through a direct interaction with JNK substrate, ATF2. |
Q62572284 | GST transcriptional changes induced by a toxic Microcystis aeruginosa strain in two bivalve species during exposure and recovery phases |
Q43913774 | GSTB1-1 from Proteus mirabilis: a snapshot of an enzyme in the evolutionary pathway from a redox enzyme to a conjugating enzyme |
Q54978826 | GSTM3 and GSTP1: novel players driving tumor progression in cervical cancer. |
Q38958277 | GSTM3 reverses the resistance of hepatoma cells to radiation by regulating the expression of cell cycle/apoptosis-related molecules |
Q28363395 | GSTP1 CpG island hypermethylation is responsible for the absence of GSTP1 expression in human prostate cancer cells |
Q36524988 | GSTP1 Loss results in accumulation of oxidative DNA base damage and promotes prostate cancer cell survival following exposure to protracted oxidative stress |
Q36044627 | GSTP1 and GSTO1 single nucleotide polymorphisms and the response of bladder cancer patients to intravesical chemotherapy |
Q42501865 | GSTP1 expression predicts poor pathological complete response to neoadjuvant chemotherapy in ER-negative breast cancer |
Q39449319 | GSTP1 hypermethylation is associated with reduced protein expression, aggressive disease and prognosis in neuroblastoma |
Q34316742 | GSTP1 methylation and polymorphism increase the risk of breast cancer and the effects of diet and lifestyle in breast cancer patients. |
Q35740802 | GSTT1 is upregulated by oxidative stress through p38-MK2 signaling pathway in human granulosa cells: possible association with mitochondrial activity |
Q46367140 | GSTpi expression in MPTP-induced dopaminergic neurodegeneration of C57BL/6 mouse midbrain and striatum |
Q35616756 | GSTpi expression mediates dopaminergic neuron sensitivity in experimental parkinsonism |
Q92576731 | GSTpi regulates VE-cadherin stabilization through promoting S-glutathionylation of Src |
Q24306200 | Gene and protein characterization of the human glutathione S-transferase kappa and evidence for a peroxisomal localization |
Q34682560 | Gene polymorphisms in cyclophosphamide metabolism pathway,treatment-related toxicity, and disease-free survival in SWOG 8897 clinical trial for breast cancer |
Q37260599 | Gene therapy for cancer through adenovirus vector‑mediated expression of the Ad5 early region gene 1A based on loss of IGF2 imprinting |
Q59350747 | Genetic Polymorphism of the Glutathione S-transferase Pi 1 (GSTP1) and Susceptibility to Cervical Cancer in Human Papilloma Virus Infected Northeastern Thai Women |
Q40170870 | Genetic Polymorphisms in Genes Related to Oxidative Stress (GSTP1, GSTM1, GSTT1, CAT, MnSOD, MPO, eNOS) and Survival of Rectal Cancer Patients after Radiotherapy |
Q54566243 | Genetic polymorphisms associated with adverse events and elimination of methotrexate in childhood acute lymphoblastic leukemia and malignant lymphoma. |
Q43217463 | Genetic polymorphisms in GST genes and survival of colorectal cancer patients treated with chemotherapy |
Q37293994 | Genetic variants associated with cisplatin-induced ototoxicity |
Q31647100 | Genomic organization and putative promoters of highly conserved glutathione S-transferases originating by alternative splicing in Anopheles dirus |
Q33596557 | Gentiana manshurica Kitagawa prevents acetaminophen-induced acute hepatic injury in mice via inhibiting JNK/ERK MAPK pathway |
Q38229956 | Getting ready for building: signaling and autophagosome biogenesis. |
Q52714421 | Glutathione S-Transferase P1 Protects Against Amodiaquine Quinoneimines-Induced Cytotoxicity but Does Not Prevent Activation of Endoplasmic Reticulum Stress in HepG2 Cells. |
Q52665601 | Glutathione S-Transferase Pi Prevents Sepsis-Related High Mobility Group Box-1 Protein Translocation and Release. |
Q78765497 | Glutathione S-transferase GSTP1 genotypes are associated with response to androgen ablation therapy in advanced prostate cancer |
Q35602805 | Glutathione S-transferase P protects against cyclophosphamide-induced cardiotoxicity in mice |
Q27853038 | Glutathione S-transferase P1 (GSTP1) directly influences platinum drug chemosensitivity in ovarian tumour cell lines |
Q36786473 | Glutathione S-transferase P1 Ile105Val polymorphism modulates allergen-induced airway inflammation in human atopic asthmatics in vivo |
Q53354190 | Glutathione S-transferase P1 suppresses iNOS protein stability in RAW264.7 macrophage-like cells after LPS stimulation. |
Q54473737 | Glutathione S-transferase P1-1 as a target for mesothelioma treatment. |
Q61814602 | Glutathione S-transferase Pi 1 is a valuable predictor for cancer drug resistance in esophageal squamous cell carcinoma |
Q43627951 | Glutathione S-transferase Pi is a dopamine-inducible suppressor of dopamine-induced apoptosis in PC12 cells |
Q36617925 | Glutathione S-transferase class μ regulation of apoptosis signal-regulating kinase 1 protein during VCD-induced ovotoxicity in neonatal rat ovaries |
Q28207670 | Glutathione S-transferase mu modulates the stress-activated signals by suppressing apoptosis signal-regulating kinase 1 |
Q48545889 | Glutathione S-transferase pi mediates MPTP-induced c-Jun N-terminal kinase activation in the nigrostriatal pathway |
Q36787561 | Glutathione S-transferase pi modulates NF-κB activation and pro-inflammatory responses in lung epithelial cells |
Q36426775 | Glutathione S-transferase polymorphisms: cancer incidence and therapy |
Q47549970 | Glutathione S-transferase protein expression in different life stages of zebrafish (Danio rerio). |
Q91229426 | Glutathione S-transferases P1 protects breast cancer cell from adriamycin-induced cell death through promoting autophagy |
Q36363170 | Glutathione S-transferases as regulators of kinase pathways and anticancer drug targets |
Q37474341 | Glutathione S-transferases in kidney and urinary bladder tumors |
Q28578663 | Glutathione S-transferases interact with AMP-activated protein kinase: evidence for S-glutathionylation and activation in vitro |
Q91708847 | Glutathione S-transferasesP1 AA (105Ile) allele increases oral cancer risk, interacts strongly with c-Jun Kinase and weakly detoxifies areca-nut metabolites |
Q37327903 | Glutathione Transferase (GST)-Activated Prodrugs. |
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Q60932204 | Glutathione Transferases: Potential Targets to Overcome Chemoresistance in Solid Tumors |
Q35642624 | Glutathione analogues in cancer treatment |
Q64983490 | Glutathione and ABC transporters as determinants of sensitivity to oxidative and nitrosative stress. |
Q36221338 | Glutathione and modulation of cell apoptosis |
Q35683084 | Glutathione and redox signaling in substance abuse |
Q35027940 | Glutathione conjugates and their synthetic derivatives as inhibitors of glutathione-dependent enzymes involved in cancer and drug resistance |
Q37078480 | Glutathione metabolism and Parkinson's disease |
Q34027127 | Glutathione peroxidase-2 protects from allergen-induced airway inflammation in mice |
Q36798838 | Glutathione s-transferase p1: gene sequence variation and functional genomic studies |
Q35972073 | Glutathione s-transferases in pediatric cancer |
Q43767233 | Glutathione transferase P1 polymorphism in neuroblastoma studied by endonuclease restriction mapping |
Q45962524 | Glutathione transferase P1: an endogenous inhibitor of allergic responses in a mouse model of asthma. |
Q37837879 | Glutathione transferase zeta: discovery, polymorphic variants, catalysis, inactivation, and properties of Gstz1-/- mice |
Q36347131 | Glutathione transferases P1/P2 regulate the timing of signaling pathway activations and cell cycle progression during mouse liver regeneration |
Q24655419 | Glutathione transferases are structural and functional outliers in the thioredoxin fold |
Q34123770 | Glutathione transferases as mediators of signaling pathways involved in cell proliferation and cell death |
Q34172648 | Glutathione transferases: a structural perspective |
Q48181201 | Glutathione transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases. |
Q28565510 | Glutathione-S-transferase P1 is a critical regulator of Cdk5 kinase activity |
Q34355370 | Glutathione-S-transferase family of enzymes. |
Q43139246 | Glutathione-s-transferase-pi expression in early breast cancer: association with outcome and response to chemotherapy |
Q36326547 | Glutathione-s-transferases as determinants of cell survival and death |
Q37394472 | Gsta4 Null Mouse Embryonic Fibroblasts Exhibit Enhanced Sensitivity to Oxidants: Role of 4-Hydroxynonenal in Oxidant Toxicity |
Q42833714 | H2O2-dependent activation of GCLC-ARE4 reporter occurs by mitogen-activated protein kinase pathways without oxidation of cellular glutathione or thioredoxin-1. |
Q36728257 | HDAC1 inhibition by maspin abrogates epigenetic silencing of glutathione S-transferase pi in prostate carcinoma cells |
Q73563311 | Hepatocyte growth factor induces apoptosis through the extrinsic pathway in hepatoma cells: favouring role of hypoxia-inducible factor-1 deficiency |
Q92975834 | High-fat diet in a mouse insulin-resistant model induces widespread rewiring of the phosphotyrosine signaling network |
Q34146338 | How does glucose generate oxidative stress in peripheral nerve? |
Q28505337 | Hsp70 inhibits lipopolysaccharide-induced NF-kappaB activation by interacting with TRAF6 and inhibiting its ubiquitination |
Q34271504 | Hsp72 functions as a natural inhibitory protein of c-Jun N-terminal kinase |
Q36855847 | Hsp90β is involved in the development of high salt-diet-induced nephropathy via interaction with various signalling proteins |
Q39086596 | Human GSTA1-1 reduces c-Jun N-terminal kinase signalling and apoptosis in Caco-2 cells |
Q22010783 | Human JIK, a novel member of the STE20 kinase family that inhibits JNK and is negatively regulated by epidermal growth factor |
Q36363137 | Human alpha class glutathione S-transferases: genetic polymorphism, expression, and susceptibility to disease |
Q38724701 | Human cytosolic glutathione-S-transferases: quantitative analysis of expression, comparative analysis of structures and inhibition strategies of isozymes involved in drug resistance |
Q24320308 | Human glutathione S-transferase P1-1 interacts with TRAF2 and regulates TRAF2-ASK1 signals |
Q24291635 | Human glutathione transferase P1-1 and nitric oxide carriers; a new role for an old enzyme |
Q46884293 | Human glutathione transferase zeta |
Q92961473 | Human glutathione-S-transferase pi potentiates the cysteine-protease activity of the Der p 1 allergen from house dust mite through a cysteine redox mechanism |
Q33510347 | Human papillomavirus-16 E7 interacts with glutathione S-transferase P1 and enhances its role in cell survival |
Q28477445 | Humanizing π-class glutathione S-transferase regulation in a mouse model alters liver toxicity in response to acetaminophen overdose |
Q27004438 | Hydrogen peroxide sensing, signaling and regulation of transcription factors |
Q28864996 | Hypochlorous acid is a potent inhibitor of GST P1-1. |
Q36943260 | Identification and functional characterization of the human glutathione S-transferase P1 gene as a novel transcriptional target of the p53 tumor suppressor gene |
Q73854145 | Identification of a glutathione-S-transferase effector domain for inhibition of jun kinase, by molecular dynamics |
Q33460911 | Identification of glutathione S-transferase pi as a protein involved in Parkinson disease progression |
Q90480780 | Identification of glutathione S-transferase π 1 as a prognostic proteomic biomarker for multiple myeloma using proteomic profiling |
Q36688743 | Identification of glutathione sulfotransferase-pi (GSTP1) as a new resveratrol targeting protein (RTP) and studies of resveratrol-responsive protein changes by resveratrol affinity chromatography. |
Q40819758 | Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue. |
Q42667595 | Identification of the critical features of a small peptide inhibitor of JNK activity |
Q46154450 | Identification, using molecular dynamics, of an effector domain of the ras-binding domain of the raf-p74 protein that is uniquely involved in oncogenic ras-p21 signaling |
Q43928586 | Ile105Val GSTP1 polymorphism and susceptibility to colorectal carcinoma in Bulgarian population |
Q37521873 | Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis |
Q34506617 | Inactivation of human salivary glutathione transferase P1-1 by hypothiocyanite: a post-translational control system in search of a role |
Q28589006 | Increased constitutive c-Jun N-terminal kinase signaling in mice lacking glutathione S-transferase Pi |
Q44699030 | Increased myeloproliferation in glutathione S-transferase pi-deficient mice is associated with a deregulation of JNK and Janus kinase/STAT pathways |
Q35823922 | Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi. |
Q39163060 | Increased skin papilloma formation in mice lacking glutathione transferase GSTP. |
Q55024919 | Induction of apoptosis and cell cycle arrest in mouse colon 26 cells by benastatin A. |
Q40803270 | Induction of beta-transducin repeat-containing protein by JNK signaling and its role in the activation of NF-kappaB. |
Q60656269 | Influence of genetic background and oxidative stress response on risk of mandibular osteoradionecrosis after radiotherapy of head and neck cancer |
Q43600441 | Influence of proteasome and redox state on heat shock-induced activation of stress kinases, AP-1 and HSF. |
Q38045418 | Inhibition and induction of glutathione S-transferases by flavonoids: possible pharmacological and toxicological consequences |
Q42496040 | Inhibition of aberrant and constitutive phosphorylation of the high-molecular-mass neurofilament subunit by CEP-1347 (KT7515), an inhibitor of the stress-activated protein kinase signaling pathway |
Q90749046 | Inhibition of glutathione S-transferase-pi triggers c-jun N-terminal kinase-dependent neuronal death in Zn-induced Parkinsonism |
Q39812389 | Insulin resistance and hepatocarcinogenesis |
Q41829379 | Interaction of Omega, Sigma, and Theta glutathione transferases with p38b mitogen-activated protein kinase from the fruit fly, Drosophila melanogaster |
Q44279157 | Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems |
Q36790471 | Interplay between Hepatitis C Virus and Redox Cell Signaling |
Q38928796 | Investigations on dendrimer space reveal solid and liquid tumor growth-inhibition by original phosphorus-based dendrimers and the corresponding monomers and dendrons with ethacrynic acid motifs |
Q46931476 | Involvement of glutathione/glutathione S-transferase antioxidant system in butyrate-inhibited vascular smooth muscle cell proliferation |
Q40634523 | Involvement of the JNK-like protein of the Aedes albopictus mosquito cell line, C6/36, in phagocytosis, endocytosis and infection of West Nile virus |
Q43093356 | Isoenzyme profile of glutathione transferases in transitional cell carcinoma of upper urinary tract. |
Q42647706 | Isolation of hyperactive mutants of the MAPK p38/Hog1 that are independent of MAPK kinase activation |
Q33887876 | JNK and p38 stresskinases--degenerative effectors of signal-transduction-cascades in the nervous system |
Q28564577 | JNK1 phosphorylation of SCG10 determines microtubule dynamics and axodendritic length |
Q37855792 | Knockout and transgenic mice in glutathione transferase research |
Q30975969 | Lack of glutathione conjugation to adriamycin in human breast cancer MCF-7/DOX cells. Inhibition of glutathione S-transferase p1-1 by glutathione conjugates from anthracyclines |
Q46704667 | Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal. |
Q44172115 | Liver protection from apoptosis requires both blockage of initiator caspase activities and inhibition of ASK1/JNK pathway via glutathione S-transferase regulation. |
Q28237402 | Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia |
Q30165030 | Longevity determination genes in Drosophila melanogaster |
Q34517167 | Low levels of GSTA1 expression are required for Caco-2 cell proliferation |
Q35902785 | Lymphoma cells with increased anti-oxidant defenses acquire chemoresistance |
Q37420626 | Markedly enhanced colon tumorigenesis in Apc(Min) mice lacking glutathione S-transferase Pi. |
Q39690234 | Mechanisms of 4-hydroxy-2-nonenal induced pro- and anti-apoptotic signaling |
Q26998806 | Mechanisms of drug-induced liver injury |
Q38077215 | Metabolic triad in brain aging: mitochondria, insulin/IGF-1 signalling and JNK signalling |
Q35102961 | Mice deficient in glutathione transferase zeta/maleylacetoacetate isomerase exhibit a range of pathological changes and elevated expression of alpha, mu, and pi class glutathione transferases |
Q35326954 | Micro-plasticity of genomes as illustrated by the evolution of glutathione transferases in 12 Drosophila species |
Q37460232 | Mitochondrial energy metabolism and redox signaling in brain aging and neurodegeneration |
Q41880271 | Mitogen-activated protein kinase p38b interaction with delta class glutathione transferases from the fruit fly, Drosophila melanogaster |
Q24530734 | Modelling and bioinformatics studies of the human Kappa-class glutathione transferase predict a novel third glutathione transferase family with similarity to prokaryotic 2-hydroxychromene-2-carboxylate isomerases |
Q42226736 | Modulation of ASK1 expression during overexpression of Trx and HSP70 in stressed fish liver mitochondria |
Q38931697 | Modulation of apoptosis by sulforaphane is associated with PGC-1α stimulation and decreased oxidative stress in cardiac myoblasts |
Q74481047 | Molecular analysis of mitogen-activated protein kinase signaling pathways induced by reactive oxygen intermediates |
Q57807148 | Molecular evaluation of glutathione S transferase family genes in patients with sporadic colorectal cancer |
Q33951094 | Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease |
Q42807112 | N-acetylcysteine inhibits kinase phosphorylation during 3T3-L1 adipocyte differentiation. |
Q28252988 | NAD(P)H:quinone oxidoreductase 1 (NQO1, DT-diaphorase), functions and pharmacogenetics |
Q37265507 | NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology |
Q39804728 | NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death |
Q56909288 | NOV-002, a mimetic of glutathione disulfide |
Q48174531 | Natural Dietary Pigments: Potential Mediators against Hepatic Damage Induced by Over-The-Counter Non-Steroidal Anti-Inflammatory and Analgesic Drugs. |
Q40584612 | Nitrobenzoxadiazole-based GSTP1-1 inhibitors containing the full peptidyl moiety of (pseudo)glutathione |
Q37885200 | Nitrosyl iron complexes--synthesis, structure and biology |
Q38320483 | Nitrosylation of human glutathione transferase P1-1 with dinitrosyl diglutathionyl iron complex in vitro and in vivo |
Q46884286 | Nomenclature for mammalian soluble glutathione transferases |
Q43635405 | Non-Jewish Israeli IBD patients have significantly higher glutathione S-transferase GSTT1-null frequency |
Q44157636 | Non-active site residues Cys69 and Asp150 affected the enzymatic properties of glutathione S-transferase AdGSTD3-3 |
Q37258656 | Noncatalytic interactions between glutathione S-transferases and nitroalkene fatty acids modulate nitroalkene-mediated activation of peroxisomal proliferator-activated receptor gamma |
Q28397449 | Novel peptides from the RAS-p21 and p53 proteins for the treatment of cancer |
Q37029859 | Novel role for glutathione S-transferase pi. Regulator of protein S-Glutathionylation following oxidative and nitrosative stress |
Q37997003 | Novel roles of peroxiredoxins in inflammation, cancer and innate immunity |
Q40108785 | Novel use of the fluorescent dye 5-(and-6)-chloromethyl SNARF-1 acetate for the measurement of intracellular glutathione in leukemic cells and primary lymphocytes |
Q37721838 | Nrf2-Keap1 signaling as a potential target for chemoprevention of inflammation-associated carcinogenesis |
Q36209099 | On marathons and Sprints: an integrated quantitative proteomics and transcriptomics analysis of differences between slow and fast muscle fibers |
Q60960944 | On the Inhibition Mechanism of Glutathione Transferase P1 by Piperlongumine. Insight From Theory |
Q35607713 | Oral ezatiostat HCl (Telintra®, TLK199) and idiopathic chronic neutropenia (ICN): a case report of complete response of a patient with G-CSF resistant ICN following treatment with ezatiostat, a glutathione S-transferase P1-1 (GSTP1-1) inhibitor |
Q39803653 | Oxaliplatin-induced neuropathy in colorectal cancer |
Q28131725 | Oxidants, oxidative stress and the biology of ageing |
Q34397394 | Oxidation-induced intramolecular disulfide bond inactivates mitogen-activated protein kinase kinase 6 by inhibiting ATP binding |
Q51295065 | Oxidative DNA damage and activation of c-Jun N-terminal kinase pathway in fibroblasts from patients with hereditary spastic paraplegia. |
Q64084056 | Oxidative Imbalance and Kidney Damage in Cafeteria Diet-Induced Rat Model of Metabolic Syndrome: Effect of Bergamot Polyphenolic Fraction |
Q39321654 | Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis |
Q38069883 | Oxidative stress and antioxidant defense |
Q26853196 | Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models? |
Q37906539 | Oxidative stress in synapse development and function |
Q38207007 | Oxidative stress in the etiology of age-associated decline in glucose metabolism |
Q35409729 | Oxidative stress induces overgrowth of the Drosophila neuromuscular junction |
Q30433525 | Oxidative stress inhibits MEKK1 by site-specific glutathionylation in the ATP-binding domain |
Q35611511 | Oxidative stress, redox regulation and diseases of cellular differentiation |
Q37274139 | PEP-1-GSTpi protein enhanced hippocampal neuronal cell survival after oxidative damage |
Q30805871 | Peptide phage display for probing GST-protein interactions |
Q28070359 | Peroxiredoxin 1 - an antioxidant enzyme in cancer |
Q51711572 | Pharmacogenetic association between GSTP1 genetic polymorphism and febrile neutropenia in Japanese patients with early breast cancer. |
Q35553827 | Pharmacogenomics of cisplatin-induced ototoxicity |
Q41956100 | Pharmacology of a mimetic of glutathione disulfide, NOV-002. |
Q37222119 | Phase 1-2a multicenter dose-escalation study of ezatiostat hydrochloride liposomes for injection (Telintra, TLK199), a novel glutathione analog prodrug in patients with myelodysplastic syndrome. |
Q36407256 | Phosphorylation of Glutathione S-Transferase P1 (GSTP1) by Epidermal Growth Factor Receptor (EGFR) Promotes Formation of the GSTP1-c-Jun N-terminal kinase (JNK) Complex and Suppresses JNK Downstream Signaling and Apoptosis in Brain Tumor Cells |
Q40777240 | Phosphorylation of proteins and apoptosis induced by c-Jun N-terminal kinase1 activation in rat cardiomyocytes by H(2)O(2) stimulation |
Q34619307 | Piperlongumine selectively kills cancer cells and increases cisplatin antitumor activity in head and neck cancer |
Q37364876 | Pleiotropic functions of glutathione S-transferase P |
Q44934830 | Polymorphisms of GSTP1 and related genes and prostate cancer risk |
Q42951273 | Porcine glutathione transferase Alpha 2-2 is a human GST A3-3 analogue that catalyses steroid double-bond isomerization |
Q48797271 | Possible prenatal impact of sertraline on human placental glutathione S-transferase-π. |
Q34074329 | Postischemic deactivation of cardiac aldose reductase: role of glutathione S-transferase P and glutaredoxin in regeneration of reduced thiols from sulfenic acids |
Q33876235 | Prenatal acetaminophen exposure and risk of wheeze at age 5 years in an urban low-income cohort |
Q36613823 | Prognostic impact of multidrug resistance gene expression on the management of breast cancer in the context of adjuvant therapy based on a series of 171 patients |
Q46518382 | Prognostic role of glutathione S-transferase polymorphisms in acute myeloid leukemia |
Q51034997 | Promoter methylation and gene polymorphism are two independent events in regulation of GSTP1 gene expression. |
Q39985733 | Protein cysteine sulfinic acid reductase (sulfiredoxin) as a regulator of cell proliferation and drug response |
Q46922228 | Protein expression in human cumulus cells as an indicator of blastocyst formation and pregnancy success. |
Q35843744 | Protein kinase function and glutathionylation |
Q34341284 | Proteomic analysis of glutathione S-transferase isoforms in mouse liver mitochondria |
Q40639543 | Proteomic analysis of hematopoietic stem cell-like fractions in leukemic disorders |
Q34138958 | Proteomic and mass spectroscopic quantitation of protein S-nitrosation differentiates NO-donors |
Q24811682 | Proteomic approaches to characterize protein modifications: new tools to study the effects of environmental exposures |
Q33213431 | Proteomic detection of hydrogen peroxide-sensitive thiol proteins in Jurkat cells |
Q34082869 | Proteomic signatures of human oral epithelial cells in HIV-infected subjects |
Q39671003 | Protoapigenone, a natural derivative of apigenin, induces mitogen-activated protein kinase-dependent apoptosis in human breast cancer cells associated with induction of oxidative stress and inhibition of glutathione S-transferase π |
Q28345250 | Purification and characterization of a glutathione S-transferase Omega in pig: evidence for two distinct organ-specific transcripts |
Q35956182 | Quinone reductases multitasking in the metabolic world |
Q39266098 | Quinone-induced activation of Keap1/Nrf2 signaling by aspirin prodrugs masquerading as nitric oxide |
Q38843258 | Ras association domain family member 10 suppresses gastric cancer growth by cooperating with GSTP1 to regulate JNK/c-Jun/AP-1 pathway |
Q37774919 | Reactive oxygen species in TNFalpha-induced signaling and cell death. |
Q24349073 | Reactive oxygen species in the activation and regulation of intracellular signaling events |
Q60950835 | Reactive oxygen species regulate activity-dependent neuronal plasticity in |
Q41825747 | Reciprocal regulation of glutathione S-transferase spliceforms and the Drosophila c-Jun N-terminal kinase pathway components |
Q24310029 | Recombinant protein glutathione S-transferases P1 attenuates inflammation in mice |
Q37802379 | Redox Balance in the Pathogenesis of Nonalcoholic Fatty Liver Disease: Mechanisms and Therapeutic Opportunities |
Q33830140 | Redox control of liver function in health and disease |
Q35707262 | Redox control of signal transduction, gene expression and cellular senescence |
Q37772328 | Redox metabolism and malignancy |
Q34777711 | Redox platforms in cancer drug discovery and development |
Q35120722 | Redox regulation and signaling lipids in mitochondrial apoptosis |
Q37181226 | Redox regulation of cell survival |
Q33644327 | Redox regulation of tumor necrosis factor signaling |
Q28397611 | Redox-based regulation of apoptosis: S-glutathionylation as a regulatory mechanism to control cell death |
Q36756386 | Redox-based regulation of signal transduction: principles, pitfalls, and promises |
Q46470681 | Reduction of GSTP1 expression by DNA methylation correlates with clinicopathological features in pituitary adenomas |
Q38085856 | Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria |
Q28509457 | Regulation of lipopolysaccharide-induced inflammatory response by glutathione S-transferase P1 in RAW264.7 cells |
Q33989877 | Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches. |
Q41901021 | Regulation of signal transduction by glutathione transferases |
Q24293209 | Regulation of the cardiac muscle ryanodine receptor by glutathione transferases |
Q36155865 | Regulatory functions of glutathione S-transferase P1-1 unrelated to detoxification |
Q46119122 | Relationship between GSTP1 Ile(105)Val polymorphism and docetaxel-induced peripheral neuropathy: clinical evidence of a role of oxidative stress in taxane toxicity. |
Q33756205 | Relationships between metabolic and non-metabolic susceptibility factors in benzene toxicity |
Q26822957 | Repair of oxidative DNA damage and cancer: recent progress in DNA base excision repair |
Q40646994 | Resistance to phorbol 12-myristate 13-acetate-induced cell growth arrest in an HL60 cell line chronically exposed to a glutathione S-transferase π inhibitor |
Q23918077 | Respiratory burst: role in signal transduction in alveolar macrophages |
Q30765231 | Reverse two-hybrid screening identifies residues of JNK required for interaction with the kinase interaction motif of JNK-interacting protein-1. |
Q40734751 | Role for c-jun N-terminal kinase in treatment-refractory acute myeloid leukemia (AML): signaling to multidrug-efflux and hyperproliferation |
Q33965815 | Role for mitochondrial oxidants as regulators of cellular metabolism |
Q92597833 | Role of AccMGST1 in oxidative stress resistance in Apis cerana cerana |
Q40719119 | Role of GST P1-1 in mediating the effect of etoposide on human neuroblastoma cell line Sh-Sy5y |
Q38992254 | Role of Glutathione-S-transferases in neurological problems |
Q39929809 | Role of glutathione S-transferase P1-1 in the cellular detoxification of cisplatin |
Q38114436 | Role of glutathione in cancer progression and chemoresistance |
Q35916588 | Role of mitochondrial homeostasis and dynamics in Alzheimer's disease |
Q54027395 | Role of multidrug-resistance protein 2 in glutathione S-transferase P1-1-mediated resistance to 4-nitroquinoline 1-oxide toxicities in HepG2 cells. |
Q23924205 | Role of reactive oxygen species and MAPKs in vanadate-induced G2/M phase arrest |
Q33771754 | Role of redox potential and reactive oxygen species in stress signaling |
Q28140867 | Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis |
Q40870782 | Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium |
Q42022492 | Roles of Mitochondrial DNA Changes on Cancer Initiation and Progression |
Q53120803 | S-Glutathionylation of Keap1: a new role for glutathione S-transferase pi in neuronal protection. |
Q30398587 | S-glutathionylation: from molecular mechanisms to health outcomes |
Q37058729 | S-glutathionylation: indicator of cell stress and regulator of the unfolded protein response. |
Q36873620 | S-nitrosation of glutathione transferase p1-1 is controlled by the conformation of a dynamic active site helix. |
Q59613491 | Selective Inhibitors of Glutathione Transferase P1 with Trioxane Structure as Anticancer Agents |
Q45017292 | Selective expression of detoxifying glutathione transferases in mouse colon: effect of experimental colitis and the presence of bacteria |
Q38327079 | Selective induction of the tumor marker glutathione S-transferase P1 by proteasome inhibitors. |
Q40185539 | Selective protection of nuclear thioredoxin-1 and glutathione redox systems against oxidation during glucose and glutamine deficiency in human colonic epithelial cells |
Q30932122 | Selective recognition of peptide sequences by glutathione transferases: a possible mechanism for modulation of cellular stress-induced signaling pathways. |
Q24793538 | Sensitivity and fidelity of DNA microarray improved with integration of Amplified Differential Gene Expression (ADGE) |
Q35859386 | Serum glutathione S-transferase P1 1 in prediction of cardiac function |
Q37855791 | Sigma-class glutathione transferases. |
Q29615230 | Signal transduction by reactive oxygen species |
Q28142592 | Signal transduction by the JNK group of MAP kinases |
Q26829903 | Signal transduction inhibitors in treatment of myelodysplastic syndromes |
Q90703648 | Silencing of Glutathione S-Transferase Pi Inhibits Cancer Cell Growth via Oxidative Stress Induced by Mitochondria Dysfunction |
Q28909763 | Site-specific arylation of rat glutathione s-transferase A1 and A2 by bromobenzene metabolites in vivo |
Q40121643 | Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling. |
Q39166555 | Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine |
Q24533519 | Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily |
Q36231404 | Sulfiredoxin: a potential therapeutic agent? |
Q40664009 | Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells |
Q28478529 | Synergistic effects of apigenin and paclitaxel on apoptosis of cancer cells |
Q47329610 | Synthesis and activity mechanism of some novel 2-substituted benzothiazoles as hGSTP1-1 enzyme inhibitors. |
Q87544959 | Synthesis and biological evaluation of 2-substituted-5-(4-nitrophenylsulfonamido)benzoxazoles as human GST P1-1 inhibitors, and description of the binding site features |
Q45158753 | TEGDMA modulates glutathione transferase P1 activity in gingival fibroblasts |
Q34374468 | THE GSTP1 c.313A>G POLYMORPHISM MODULATES THE CARDIORESPIRATORY RESPONSE TO AEROBIC TRAINING. |
Q37299479 | TNFR1 signaling kinetics: spatiotemporal control of three phases of IKK activation by posttranslational modification |
Q37095205 | TNFalpha and reactive oxygen species in necrotic cell death |
Q34581769 | Targeted tumor gene therapy based on loss of IGF2 imprinting |
Q39446187 | Targeting GSTP1-1 induces JNK activation and leads to apoptosis in cisplatin-sensitive and -resistant human osteosarcoma cell lines. |
Q34009844 | Targeting Glutathione S-transferase M4 in Ewing sarcoma |
Q46499332 | Targeting Nrf2 with wogonin overcomes cisplatin resistance in head and neck cancer |
Q38817271 | Targeting the expression of glutathione- and sulfate-dependent detoxification enzymes in HepG2 cells by oxygen in minimal and amino acid enriched medium. |
Q54498834 | Tauroursodeoxycholic acid prevents MPTP-induced dopaminergic cell death in a mouse model of Parkinson's disease. |
Q34039684 | Testicular cancer survivorship: research strategies and recommendations |
Q41961494 | Tetramerization and cooperativity in Plasmodium falciparum glutathione S-transferase are mediated by atypic loop 113-119. |
Q40224958 | The ADP-stimulated NADPH oxidase activates the ASK-1/MKK4/JNK pathway in alveolar macrophages |
Q43011025 | The AoPR10 promoter and certain endogenous PR10 genes respond to oxidative signals in Arabidopsis |
Q28551389 | The Effect of Chronic Methamphetamine Exposure on the Hippocampal and Olfactory Bulb Neuroproteomes of Rats |
Q90067850 | The Formation of a Camalexin Biosynthetic Metabolon |
Q36128683 | The GSTM2 C-Terminal Domain Depresses Contractility and Ca2+ Transients in Neonatal Rat Ventricular Cardiomyocytes. |
Q44019750 | The Gerhard Zbinden memorial lecture: application of biochemical and genetic approaches to understanding pathways of chemical toxicity |
Q44619133 | The JNK binding domain of islet-brain 1 inhibits IL-1 induced JNK activity and apoptosis but not the transcription of key proapoptotic or protective genes in insulin-secreting cell lines |
Q24305978 | The Mu class glutathione transferase is abundant in striated muscle and is an isoform-specific regulator of ryanodine receptor calcium channels |
Q26775729 | The antioxidant master glutathione and periodontal health |
Q34269360 | The changing faces of glutathione, a cellular protagonist |
Q36990410 | The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal. |
Q27629457 | The crystal structure of the nitrogen regulation fragment of the yeast prion protein Ure2p |
Q40493236 | The effect of C-terminal fragment of JNK2 on the stability of p53 and cell proliferation |
Q22254262 | The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death |
Q33695114 | The fine-tuning of TRAF2-GSTP1-1 interaction: effect of ligand binding and in situ detection of the complex |
Q37856253 | The glutathione transferase kappa family |
Q24290416 | The glutathione transferase structural family includes a nuclear chloride channel and a ryanodine receptor calcium release channel modulator |
Q41571797 | The impact of GSTM1/GSTT1 polymorphism for the risk of oral cancer |
Q28180886 | The importance of glutathione in human disease |
Q24307307 | The inhibitory glutathione transferase M2-2 binding site is located in divergent region 3 of the cardiac ryanodine receptor |
Q37292416 | The interactions of flavonoids within neuronal signalling pathways |
Q37904152 | The interplay of glutathione-related processes in antioxidant defense |
Q28382920 | The redox state of cytochrome c modulates resistance to methotrexate in human MCF7 breast cancer cells |
Q28541169 | The role of N-acetyltransferase 8 in mesenchymal stem cell-based therapy for liver ischemia/reperfusion injury in rats |
Q24603861 | The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer |
Q34272162 | The role of glutathione-S-transferase in anti-cancer drug resistance |
Q43477300 | The role of the inhibition of glutathione-S-transferase in the protective mechanisms of ischemic postconditioning |
Q41104826 | The silkworm GSTe4 is sensitive to phoxim and protects HEK293 cells against UV-induced cell apoptosis |
Q24309820 | The specific interaction of dinitrosyl-diglutathionyl-iron complex, a natural NO carrier, with the glutathione transferase superfamily: suggestion for an evolutionary pressure in the direction of the storage of nitric oxide |
Q42156273 | The structural roles of a conserved small hydrophobic core in the active site and an ionic bridge in domain I of Delta class glutathione S-transferase |
Q40399626 | The tumor suppressor p16(INK4a) prevents cell transformation through inhibition of c-Jun phosphorylation and AP-1 activity |
Q36835830 | The use of glutathione transferase-knockout mice as pharmacological and toxicological models |
Q37564522 | Therapeutic peptides for cancer therapy. Part I - peptide inhibitors of signal transduction cascades. |
Q39430380 | Thiazolide-induced apoptosis in colorectal cancer cells is mediated via the Jun kinase-Bim axis and reveals glutathione-S-transferase P1 as Achilles' heel |
Q36347320 | Thiazolides promote apoptosis in colorectal tumor cells via MAP kinase-induced Bim and Puma activation |
Q33701863 | Through translational prospective study, the GSTP1 Ile105Val polymorphism emerges as prognostic marker in de novo large B-cell lymphoma patients |
Q34314855 | Transfection with 4-hydroxynonenal-metabolizing glutathione S-transferase isozymes leads to phenotypic transformation and immortalization of adherent cells |
Q42469077 | Transient anoxia and oxyradicals induce a region-specific activation of MAPKs in the embryonic heart |
Q28085631 | Tumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategies |
Q37285088 | Tyrosine phosphorylation of the human glutathione S-transferase P1 by epidermal growth factor receptor |
Q43524396 | Ubiquitin-proteasome system impairment and MPTP-induced oxidative stress in the brain of C57BL/6 wild-type and GSTP knockout mice |
Q38090712 | Utilization of glutathione S-transferase Mu 1- and Theta 1-null mice as animal models for absorption, distribution, metabolism, excretion and toxicity studies |
Q89977976 | Weaning Mice and Adult Mice Exhibit Differential Carbon Tetrachloride-Induced Acute Hepatotoxicity |
Q41769734 | c-Jun NH2-terminal kinase-dependent upregulation of DR5 mediates cooperative induction of apoptosis by perifosine and TRAIL. |
Q35836408 | tau kinases in the rat heat shock model: possible implications for Alzheimer disease |
Q27666187 | Site-directed mutagenesis of mouse glutathione transferase P1-1 unlocks masked cooperativity, introduces a novel mechanism for 'ping pong' kinetic behaviour, and provides further structural evidence for participation of a water molecule in proton ab |
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