Novel biosynthetic approaches to the production of unnatural amino acids using transaminases

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Novel biosynthetic approaches to the production of unnatural amino acids using transaminases is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0167-7799(98)01240-2
P8608Fatcat IDrelease_xrv6j7rnfbfalhqtkppxm5tfbm
P698PubMed publication ID9807838

P2093author name stringD P Pantaleone
I G Fotheringham
P P Taylor
R F Senkpeil
P2860cites workCrystal structure of a D-amino acid aminotransferase: how the protein controls stereoselectivityQ27729786
Three-dimensional structure of Escherichia coli branched-chain amino acid aminotransferase at 2.5 A resolutionQ27738062
Stereospecific production of the herbicide phosphinothricin (glufosinate) by transamination: cloning, characterization, and overexpression of the gene encoding a phosphinothricin-specific transaminase from Escherichia coliQ33969992
Significant improvement to the catalytic properties of aspartate aminotransferase: role of hydrophobic and charged residues in the substrate binding pocketQ38312199
Staphylococcus haemolyticus contains two D-glutamic acid biosynthetic activities, a glutamate racemase and a D-amino acid transaminaseQ39835252
Angiotensin-converting enzyme inhibitors. Mercaptan, carboxyalkyl dipeptide, and phosphinic acid inhibitors incorporating 4-substituted prolinesQ42200448
Alanine dehydrogenases from two Bacillus species with distinct thermostabilities: molecular cloning, DNA and protein sequence determination, and structural comparison with other NAD(P)(+)-dependent dehydrogenasesQ42636607
Thermostable alanine racemase from Bacillus stearothermophilus: DNA and protein sequence determination and secondary structure predictionQ43483299
Molecular weight, subunit structure, and amino acid composition of the branched chain amino acid aminotransferase of Salmonella typhimuriumQ47359142
Nucleotide sequence of the Bacillus licheniformis ATCC 10716 dat gene and comparison of the predicted amino acid sequence with those of other bacterial speciesQ48055143
Highly active and selective anticoagulants: D-Phe-Pro-Arg-H, a free tripeptide aldehyde prone to spontaneous inactivation, and its stable N-methyl derivative, D-MePhe-Pro-Arg-HQ68790146
The cloning and sequence analysis of the aspC and tyrB genes from Escherichia coli K12. Comparison of the primary structures of the aspartate aminotransferase and aromatic aminotransferase of E. coli with those of the pig aspartate aminotransferaseQ68882413
A stereo-inverting D-phenylglycine aminotransferase from Pseudomonas stutzeri ST-201: purification, characterization and application for D-phenylglycine synthesisQ73570184
Transamination in Rhodospirillum rubrumQ74673997
Bacterial transamination of the stereoisomers of diaminopimelic acid and lysineQ78266345
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)412-8
P577publication date1998-10-01
P1433published inTrends in BiotechnologyQ2451465
P1476titleNovel biosynthetic approaches to the production of unnatural amino acids using transaminases
P478volume16

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cites work (P2860)
Q39313150A Retrosynthesis Approach for Biocatalysis in Organic Synthesis
Q42249595A new target region for changing the substrate specificity of amine transaminases
Q45896039A one-pot system for production of L-2-aminobutyric acid from L-threonine by L-threonine deaminase and a NADH-regeneration system based on L-leucine dehydrogenase and formate dehydrogenase
Q51334022A recyclable biotransformation system for L-2-aminobutyric acid production based on immobilized enzyme technology.
Q45812138Active site model of (R)-selective ω-transaminase and its application to the production of D-amino acids
Q36084574Active-Site Engineering of ω-Transaminase for Production of Unnatural Amino Acids Carrying a Side Chain Bulkier than an Ethyl Substituent
Q46413962Asymmetrical synthesis of L-homophenylalanine using engineered Escherichia coli aspartate aminotransferase.
Q33796295Biocatalysis for industrial production of fine chemicals
Q62017118Biocatalyzed Enantioselective Reduction of Activated C=C Bonds: Synthesis of Enantiomerically Enriched α-Halo-β-arylpropionic Acids
Q27674660Biochemical Properties and Crystal Structure of a  -Phenylalanine Aminotransferase from Variovorax paradoxus
Q91975725Cloning and Expression of a Novel Leucine Dehydrogenase: Characterization and L-tert-Leucine Production
Q33270635Cloning and characterization of a novel beta-transaminase from Mesorhizobium sp. strain LUK: a new biocatalyst for the synthesis of enantiomerically pure beta-amino acids
Q46823150Coimmobilization of l-methioninase and glutamate dehydrogenase: Novel approach for L-homoalanine synthesis
Q35801991Continuous colorimetric screening assays for the detection of specific L- or D-α-amino acid transaminases in enzyme libraries
Q27673233Crystal Structures of Complexes of the Branched-Chain Aminotransferase from Deinococcus radiodurans with  -Ketoisocaproate and L-Glutamate Suggest the Radiation Resistance of This Enzyme for Catalysis
Q27698375Crystal structure and enzymatic properties of a broad substrate-specificity psychrophilic aminotransferase from the Antarctic soil bacterium Psychrobacter sp. B6
Q43160952Crystallization and preliminary X-ray diffraction analysis of omega-amino acid:pyruvate transaminase from Chromobacterium violaceum
Q34204833Dehydrogenases and transaminases in asymmetric synthesis
Q54342136Deracemization of unnatural amino acid: homoalanine using D-amino acid oxidase and ω-transaminase.
Q55055778Development of an amine dehydrogenase for synthesis of chiral amines.
Q100958550Diastereodivergent chiral aldehyde catalysis for asymmetric 1,6-conjugated addition and Mannich reactions
Q35244153Dihydrophenylalanine: a prephenate-derived Photorhabdus luminescens antibiotic and intermediate in dihydrostilbene biosynthesis
Q73222753Engineering of a novel biochemical pathway for the biosynthesis of L-2-aminobutyric acid in Escherichia coli K12
Q47593072Enzymatic synthesis of chiral amino-alcohols by coupling transketolase and transaminase-catalyzed reactions in a cascading continuous-flow microreactor system.
Q46175271Enzymatic synthesis of enantiopure alpha- and beta-amino acids by phenylalanine aminomutase-catalysed amination of cinnamic acid derivatives
Q35106486Enzyme characteristics of aminotransferase FumI of Sphingopyxis sp. MTA144 for deamination of hydrolyzed fumonisin B₁.
Q33778951Expanding metabolism for total biosynthesis of the nonnatural amino acid L-homoalanine
Q64090387Fermentative production of the unnatural amino acid L-2-aminobutyric acid based on metabolic engineering
Q42122309Functional and structural characterization of thermostable D-amino acid aminotransferases from Geobacillus spp.
Q44158410Identification and characterization of a new gene from Variovorax paradoxus Iso1 encoding N-acyl-D-amino acid amidohydrolase responsible for D-amino acid production.
Q36903893Implication for buried polar contacts and ion pairs in hyperthermostable enzymes
Q50989300In vitro metabolic engineering for the production of α-ketoglutarate.
Q43547012Kinetic resolution of chiral amines with omega-transaminase using an enzyme-membrane reactor
Q34232344L-selective amidase with extremely broad substrate specificity from Ochrobactrum anthropi NCIMB 40321.
Q33884992Metabolic engineering and directed evolution for the production of pharmaceuticals
Q38589496Metabolic engineering of Escherichia coli for the production of phenylpyruvate derivatives
Q46934495Metabolic engineering of the E. coli L-phenylalanine pathway for the production of D-phenylglycine (D-Phg).
Q37684585Metabolomics analysis identifies d-Alanine-d-Alanine ligase as the primary lethal target of d-Cycloserine in mycobacteria
Q46079483Molecular determinants for substrate selectivity of ω-transaminases
Q37223122N-tert-But-oxy-carbonyl-α-(2-fluoro-benzyl)-l-proline
Q98771610Overview on Multienzymatic Cascades for the Production of Non-canonical α-Amino Acids
Q43247115Phenylalanine aminomutase-catalyzed addition of ammonia to substituted cinnamic acids: a route to enantiopure alpha- and beta-amino acids
Q28762931Potential and utilization of thermophiles and thermostable enzymes in biorefining
Q37860247Process considerations for the asymmetric synthesis of chiral amines using transaminases.
Q30914385Purification, characterization, and molecular cloning of a novel amine:pyruvate transaminase from Vibrio fluvialis JS17.
Q36585088Purification, crystallization and preliminary X-ray crystallographic analysis of branched-chain aminotransferase from Deinococcus radiodurans
Q46182856Rapid screening and scale-up of transaminase catalysed reactions
Q59811767Single point mutations reveal amino acid residues important for Chromobacterium violaceum transaminase activity in the production of unnatural amino acids
Q27670553Structural Determinants of the  -Selectivity of a Bacterial Aminotransferase
Q54659463Supramolecular architectures of N-acetyl-L-proline monohydrate and N-benzyl-L-proline.
Q27621326The molecular structure of hyperthermostable aromatic aminotransferase with novel substrate specificity from Pyrococcus horikoshii
Q44397501The structural interpretations of residue Ser297 in catalytic efficiency of Escherichia coli phenylalanine aminotransferase
Q27682128The substrate specificity, enantioselectivity and structure of the (R)-selective amine : pyruvate transaminase fromNectria haematococca
Q61810225Thermostable Branched-Chain Amino Acid Transaminases From the Archaea and : Biochemical and Structural Characterization
Q37980280Transaminases for the synthesis of enantiopure beta-amino acids
Q34651242Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide.
Q33221268Use of enrichment culture for directed evolution of the Vibrio fluvialis JS17 omega-transaminase, which is resistant to product inhibition by aliphatic ketones
Q37314315omega-Amino acid:pyruvate transaminase from Alcaligenes denitrificans Y2k-2: a new catalyst for kinetic resolution of beta-amino acids and amines
Q36970635ω-Transaminase from Ochrobactrum anthropi is devoid of substrate and product inhibitions
Q45395818ω-Transaminase-catalyzed asymmetric synthesis of unnatural amino acids using isopropylamine as an amino donor

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