Upregulation of cyclin T1/CDK9 complexes during T cell activation

scientific article

Upregulation of cyclin T1/CDK9 complexes during T cell activation is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1003693231
P356DOI10.1038/SJ.ONC.1202548
P8608Fatcat IDrelease_3rqkwg27cbbitf74trd372xphq
P698PubMed publication ID9872325
P5875ResearchGate publication ID13416771

P2093author name stringD H Price
J Peng
X Graña
J Garriga
M Parreño
E E Henderson
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectT cell activationQ14863969
P304page(s)3093-102
P577publication date1998-12-17
P1433published inOncogeneQ1568657
P1476titleUpregulation of cyclin T1/CDK9 complexes during T cell activation
P478volume17

Reverse relations

cites work (P2860)
Q24310643Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription
Q28115623Activation of MyoD-dependent transcription by cdk9/cyclin T2
Q35746236Activation of P-TEFb at sites of dual HIV/TB infection, and inhibition of MTB-induced HIV transcriptional activation by the inhibitor of CDK9, Indirubin-3'-monoxime
Q39606992Activation of human immunodeficiency virus transcription in T cells revisited: NF-kappaB p65 stimulates transcriptional elongation
Q33836069Antiapoptotic function of Cdk9 (TAK/P-TEFb) in U937 promonocytic cells
Q28292152Antiviral activity of CYC202 in HIV-1-infected cells
Q39591738Binding of Tat to TAR and recruitment of positive transcription elongation factor b occur independently in bovine immunodeficiency virus
Q42812732CDK9 has the intrinsic property to shuttle between nucleus and cytoplasm, and enhanced expression of cyclin T1 promotes its nuclear localization
Q35161639CDK9 is constitutively expressed throughout the cell cycle, and its steady-state expression is independent of SKP2.
Q33302108Cellular mRNA activates transcription elongation by displacing 7SK RNA.
Q38333164Closing loop base pairs in RNA loop-loop complexes: structural behavior, interaction energy and solvation analysis through molecular dynamics simulations
Q34121518Complexities in the development of cyclin-dependent kinase inhibitor drugs
Q37645582Curing HIV: Pharmacologic approaches to target HIV-1 latency
Q28138707Cyclin K functions as a CDK9 regulatory subunit and participates in RNA polymerase II transcription
Q24301811Cyclin K inhibits HIV-1 gene expression and replication by interfering with cyclin-dependent kinase 9 (CDK9)-cyclin T1 interaction in Nef-dependent manner
Q42052356Cyclin T1 and CDK9 T-loop phosphorylation are downregulated during establishment of HIV-1 latency in primary resting memory CD4+ T cells.
Q39681689Cyclin T1 expression is mediated by a complex and constitutively active promoter and does not limit human immunodeficiency virus type 1 Tat function in unstimulated primary lymphocytes
Q40495577Cyclin-dependent kinase 9 is required for tumor necrosis factor-alpha-stimulated matrix metalloproteinase-9 expression in human lung adenocarcinoma cells
Q36796438Cyclins and cell cycle control in cancer and disease
Q38120534Deregulations in the cyclin-dependent kinase-9-related pathway in cancer: implications for drug discovery and development
Q40642204Differential activation of Tat variants in mitogen-stimulated cells: implications for HIV-1 postintegration latency
Q36419687Direct inhibition of CDK9 blocks HIV-1 replication without preventing T-cell activation in primary human peripheral blood lymphocytes
Q37269112Dormancy activation mechanism of tracheal stem cells
Q38557763Effects of prostratin on Cyclin T1/P-TEFb function and the gene expression profile in primary resting CD4+ T cells
Q64120094Entry of Polarized Effector Cells into Quiescence Forces HIV Latency
Q39933477Epigenetic silencing of human immunodeficiency virus (HIV) transcription by formation of restrictive chromatin structures at the viral long terminal repeat drives the progressive entry of HIV into latency
Q33910799Flavopiridol inhibits P-TEFb and blocks HIV-1 replication
Q37368973Functional evolution of cyclin-dependent kinases.
Q46688122Genome-wide annotation and expression profiling of cell cycle regulatory genes in Chlamydomonas reinhardtii.
Q33711447HIV-1 Tat: coping with negative elongation factors
Q38273477HIV-1 replication and latency are regulated by translational control of cyclin T1
Q45395775Hexamethylbisacetamide and disruption of human immunodeficiency virus type 1 latency in CD4(+) T cells
Q59357225Host and Viral Factors Influencing Interplay between the Macrophage and HIV-1
Q34228694Human cytomegalovirus infection induces specific hyperphosphorylation of the carboxyl-terminal domain of the large subunit of RNA polymerase II that is associated with changes in the abundance, activity, and localization of cdk9 and cdk7.
Q42802816Identification of a novel isoform of Cdk9.
Q41274276Identification of novel CDK9 and Cyclin T1-associated protein complexes (CCAPs) whose siRNA depletion enhances HIV-1 Tat function
Q36334152Increased cyclin T1 expression as a favorable prognostic factor in treating gastric adenocarcinoma
Q33849629Induction of TAK (cyclin T1/P-TEFb) in purified resting CD4(+) T lymphocytes by combination of cytokines
Q36850296Inhibition of HIV-1 transcription and replication by a newly identified cyclin T1 splice variant.
Q28344365Inhibition of human immunodeficiency virus type 1 transcription by chemical cyclin-dependent kinase inhibitors
Q24548261Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome
Q47844049Isolation and characterization of the human cyclin T1 promoter
Q40118214Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR.
Q34033135NF-kappa B and HIV: linking viral and immune activation
Q33602605Negative elongation factor is required for the maintenance of proviral latency but does not induce promoter-proximal pausing of RNA polymerase II on the HIV long terminal repeat
Q89782162P-TEFb as A Promising Therapeutic Target
Q29620167P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II
Q38008733Perspective of cyclin-dependent kinase 9 (CDK9) as a drug target.
Q36953714Positive cyclin T expression as a favorable prognostic factor in treating gastric gastrointestinal stromal tumors
Q37992154RNA polymerase II elongation control
Q34960186RNA polymerase II transcription elongation control
Q35826285Regulation of cyclin T1 and HIV-1 Replication by microRNAs in resting CD4+ T lymphocytes.
Q64259746Regulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells
Q24552532Relief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter
Q38111619Restrictions to HIV-1 replication in resting CD4+ T lymphocytes
Q40375929SUN2 Silencing Impairs CD4 T Cell Proliferation and Alters Sensitivity to HIV-1 Infection Independently of Cyclophilin A.
Q35227888Selective HDAC inhibition for the disruption of latent HIV-1 infection
Q37437860Selective control of gene expression by CDK9 in human cells
Q36738991Serum cyclin-dependent kinase 9 is a potential biomarker of atherosclerotic inflammation
Q92216465Strength of T cell signaling regulates HIV-1 replication and establishment of latency
Q33922921T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes.
Q93218253Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer
Q42117931The Role of RNA Polymerase II Elongation Control in HIV-1 Gene Expression, Replication, and Latency
Q24298498The functional role of an interleukin 6-inducible CDK9.STAT3 complex in human gamma-fibrinogen gene expression
Q39685314Transient induction of cyclin T1 during human macrophage differentiation regulates human immunodeficiency virus type 1 Tat transactivation function.
Q35550068Up-regulation of CDK9 kinase activity and Mcl-1 stability contributes to the acquired resistance to cyclin-dependent kinase inhibitors in leukemia
Q36202709Use of ATP analogs to inhibit HIV-1 transcription
Q40786197Visualization of in vivo direct interaction between HIV-1 TAT and human cyclin T1 in specific subcellular compartments by fluorescence resonance energy transfer

Search more.