| scholarly article | Q13442814 |
| P50 | author | Andrew P Rice | Q55277928 |
| Alberto Bosque | Q55297554 | ||
| P2093 | author name string | Vicente Planelles | |
| Marylinda Famiglietti | |||
| Sona Budhiraja | |||
| P2860 | cites work | The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK | Q21136168 |
| Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA | Q24298519 | ||
| Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated promoter of human immunodeficiency virus type 1 (HIV-1) by the HIV-1 repressor YY1 and HIV-1 activator Tat | Q24537275 | ||
| Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor | Q24563382 | ||
| 7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes | Q28116607 | ||
| NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation | Q28141291 | ||
| The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription | Q28206012 | ||
| The challenge of viral reservoirs in HIV-1 infection | Q28216956 | ||
| Regulation of TAK/P-TEFb in CD4+ T lymphocytes and macrophages | Q28253165 | ||
| Controlling the elongation phase of transcription with P-TEFb | Q28255518 | ||
| A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA | Q28263974 | ||
| A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis | Q28267330 | ||
| Upregulation of cyclin T1/CDK9 complexes during T cell activation | Q28292597 | ||
| Epigenetic regulation of HIV-1 latency by cytosine methylation | Q28475636 | ||
| Directly infected resting CD4+T cells can produce HIV Gag without spreading infection in a model of HIV latency | Q28728736 | ||
| Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro | Q29614788 | ||
| HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription | Q30835037 | ||
| Homeostatic proliferation fails to efficiently reactivate HIV-1 latently infected central memory CD4+ T cells | Q31036545 | ||
| Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells | Q33250088 | ||
| Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation | Q33425135 | ||
| Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors | Q33604662 | ||
| Induction of TAK (cyclin T1/P-TEFb) in purified resting CD4(+) T lymphocytes by combination of cytokines | Q33849629 | ||
| T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes. | Q33922921 | ||
| Transcriptional and posttranscriptional regulation of HIV-1 gene expression | Q34030804 | ||
| The molecular biology of HIV latency: breaking and restoring the Tat-dependent transcriptional circuit | Q34544409 | ||
| Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes | Q34695803 | ||
| HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription | Q34896128 | ||
| High-throughput screening uncovers a compound that activates latent HIV-1 and acts cooperatively with a histone deacetylase (HDAC) inhibitor. | Q35065109 | ||
| Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation | Q35077057 | ||
| The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein | Q35211232 | ||
| Expression and reactivation of HIV in a chemokine induced model of HIV latency in primary resting CD4+ T cells | Q35549754 | ||
| Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription. | Q35804608 | ||
| Regulation of cyclin T1 and HIV-1 Replication by microRNAs in resting CD4+ T lymphocytes. | Q35826285 | ||
| Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells | Q37039142 | ||
| Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II | Q37103512 | ||
| Poised polymerases: on your mark...get set...go! | Q37136094 | ||
| Characterization of Cdk9 T-loop phosphorylation in resting and activated CD4(+) T lymphocytes. | Q37429329 | ||
| Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs | Q37615893 | ||
| Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies | Q37644561 | ||
| Studies of HIV-1 latency in an ex vivo model that uses primary central memory T cells | Q37802560 | ||
| The control of HIV transcription: keeping RNA polymerase II on track | Q37958430 | ||
| HIV latency | Q37974218 | ||
| HIV-1 replication and latency are regulated by translational control of cyclin T1 | Q38273477 | ||
| Effects of prostratin on Cyclin T1/P-TEFb function and the gene expression profile in primary resting CD4+ T cells | Q38557763 | ||
| HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP | Q39703646 | ||
| Establishment of HIV latency in primary CD4+ cells is due to epigenetic transcriptional silencing and P-TEFb restriction | Q39712159 | ||
| Epigenetic silencing of human immunodeficiency virus (HIV) transcription by formation of restrictive chromatin structures at the viral long terminal repeat drives the progressive entry of HIV into latency | Q39933477 | ||
| Human immunodeficiency virus type 1 infection induces cyclin T1 expression in macrophages. | Q41039158 | ||
| Phosphatase PPM1A negatively regulates P-TEFb function in resting CD4(+) T cells and inhibits HIV-1 gene expression | Q42112998 | ||
| Cdk9 T-loop phosphorylation is regulated by the calcium signaling pathway | Q42847637 | ||
| HIV RNA in plasma rebounds within days during structured treatment interruptions | Q43442867 | ||
| Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA. | Q46675052 | ||
| Re-emergence of HIV after stopping therapy | Q59060012 | ||
| Increased association of 7SK snRNA with Tat cofactor P-TEFb following activation of peripheral blood lymphocytes | Q79254743 | ||
| Interleukin-10 inhibits HIV-1 LTR-directed gene expression in human macrophages through the induction of cyclin T1 proteolysis | Q79745144 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | phosphorylation | Q242736 |
| P304 | page(s) | 1211-1220 | |
| P577 | publication date | 2012-11-14 | |
| P1433 | published in | Journal of Virology | Q1251128 |
| P1476 | title | Cyclin T1 and CDK9 T-loop phosphorylation are downregulated during establishment of HIV-1 latency in primary resting memory CD4+ T cells | |
| P478 | volume | 87 |
| Q63351215 | Activating Latent HIV by Inhibiting Bromodomain Proteins |
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| Q28538015 | An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients |
| Q47120827 | BET inhibitors RVX-208 and PFI-1 reactivate HIV-1 from latency |
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| Q38078562 | Cellular and molecular mechanisms involved in the establishment of HIV-1 latency |
| Q35894061 | Cocaine promotes both initiation and elongation phase of HIV-1 transcription by activating NF-κB and MSK1 and inducing selective epigenetic modifications at HIV-1 LTR |
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| Q54216878 | Cyclin-dependent kinase 7 (CDK7)-mediated phosphorylation of the CDK9 activation loop promotes P-TEFb assembly with Tat and proviral HIV reactivation. |
| Q34265421 | Cyclin-dependent kinase 9 may as a novel target in downregulating the atherosclerosis inflammation (Review). |
| Q38995028 | Cyclin-dependent kinases as therapeutic targets for HIV-1 infection. |
| Q36644877 | Elevated Plasma Viral Loads in Romidepsin-Treated Simian Immunodeficiency Virus-Infected Rhesus Macaques on Suppressive Combination Antiretroviral Therapy |
| Q34877762 | Epigenetic heterogeneity in HIV-1 latency establishment |
| Q35252186 | Eradicating HIV-1 infection: seeking to clear a persistent pathogen |
| Q40752303 | HIV Provirus Stably Reproduces Parental Latent and Induced Transcription Phenotypes Regardless of the Chromosomal Integration Site |
| Q38271132 | HIV eradication: combinatorial approaches to activate latent viruses |
| Q38248964 | HIV-1 endocytosis in astrocytes: a kiss of death or survival of the fittest? |
| Q38204866 | HIV-1 latency: an update of molecular mechanisms and therapeutic strategies |
| Q64253074 | HUSH, a Link Between Intrinsic Immunity and HIV Latency |
| Q39173861 | Histone deacetylase inhibitors (HDACis) that release the positive transcription elongation factor b (P-TEFb) from its inhibitory complex also activate HIV transcription |
| Q45966440 | Host Methyltransferases and Demethylases: Potential New Epigenetic Targets for HIV Cure Strategies and Beyond. |
| Q92344530 | Interferon-inducible TRIM22 contributes to maintenance of HIV-1 proviral latency in T cell lines |
| Q52680804 | Long Noncoding RNA uc002yug.2 Activates HIV-1 Latency through Regulation of mRNA Levels of Various RUNX1 Isoforms and Increased Tat Expression. |
| Q34958392 | Measuring glutathione redox potential of HIV-1-infected macrophages |
| Q33815611 | Mechanisms of HIV Transcriptional Regulation by Drugs of Abuse |
| Q35819184 | Modeling the Effects of Vorinostat In Vivo Reveals both Transient and Delayed HIV Transcriptional Activation and Minimal Killing of Latently Infected Cells |
| Q47600043 | Molecular Control of HIV and SIV Latency |
| Q28487524 | Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes |
| Q38727211 | Promising Role of Toll-Like Receptor 8 Agonist in Concert with Prostratin for Activation of Silent HIV. |
| Q33589167 | Proteasome inhibitors act as bifunctional antagonists of human immunodeficiency virus type 1 latency and replication |
| Q47587530 | Proteomic Profiling of a Primary CD4+ T Cell Model of HIV-1 Latency Identifies Proteins Whose Differential Expression Correlates with Reactivation of Latent HIV-1. |
| Q37305160 | Reactivation of latent HIV-1 in central memory CD4⁺ T cells through TLR-1/2 stimulation |
| Q38177273 | Reactivation of latent HIV: do all roads go through P-TEFb? |
| Q37553804 | Regulation of CDK9 activity by phosphorylation and dephosphorylation. |
| Q64259746 | Regulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells |
| Q26782187 | Roles of microRNAs and long-noncoding RNAs in human immunodeficiency virus replication |
| Q36601909 | Short Communication: The Broad-Spectrum Histone Deacetylase Inhibitors Vorinostat and Panobinostat Activate Latent HIV in CD4(+) T Cells In Part Through Phosphorylation of the T-Loop of the CDK9 Subunit of P-TEFb. |
| Q39023875 | Short communication: SAHA (vorinostat) induces CDK9 Thr-186 (T-loop) phosphorylation in resting CD4+ T cells: implications for reactivation of latent HIV. |
| Q35767091 | Subversion of Cell Cycle Regulatory Mechanisms by HIV. |
| Q38179375 | T Cell Transcription Factors and Their Impact on HIV Expression |
| Q61814094 | TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb |
| Q52431127 | Tackling HIV Persistence: Pharmacological versus CRISPR-Based Shock Strategies. |
| Q54210140 | Targeting the Latent Reservoir for HIV-1. |
| Q36790027 | The BET inhibitor OTX015 reactivates latent HIV-1 through P-TEFb |
| Q40135003 | The HIV-1 Tat protein: mechanism of action and target for HIV-1 cure strategies. |
| Q36906001 | The effects of cocaine on HIV transcription |
| Q26999858 | Transcriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cure |
| Q90047078 | Tyrosine Kinase Inhibition: a New Perspective in the Fight against HIV |
| Q35034218 | ZASC1 stimulates HIV-1 transcription elongation by recruiting P-TEFb and TAT to the LTR promoter |
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