Subversion of Cell Cycle Regulatory Mechanisms by HIV.

scientific article published on June 2015

Subversion of Cell Cycle Regulatory Mechanisms by HIV. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.CHOM.2015.05.010
P932PMC publication ID4476643
P698PubMed publication ID26067601

P50authorAndrew P RiceQ55277928
Jason T. KimataQ55283645
P2093author name stringAndrew P Rice
Jason T Kimata
P2860cites workHIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligaseQ24297940
Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensingQ24318920
Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune responseQ24338296
SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by VpxQ24605940
Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 proteinQ24635842
Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycleQ24680705
HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1Q24681112
Transcriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cureQ26999858
Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage divisionQ28261164
The role of Vpr in HIV-1 pathogenesisQ28301540
Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infectionQ28472652
HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligaseQ33290831
Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1Q33602815
The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1Q34140181
Quantification of unintegrated HIV-1 DNA at the single cell level in vivoQ34264608
The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylationQ34340339
Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cellsQ34663141
Cyclin L2 is a critical HIV dependency factor in macrophages that controls SAMHD1 abundanceQ34667185
Determinants for degradation of SAMHD1, Mus81 and induction of G2 arrest in HIV-1 Vpr and SIVagm Vpr.Q35684278
Regulation of cyclin T1 and HIV-1 Replication by microRNAs in resting CD4+ T lymphocytes.Q35826285
Progression to AIDS in the absence of a gene for vpr or vpx.Q35837777
CyclinA2-Cyclin-dependent Kinase Regulates SAMHD1 Protein Phosphohydrolase DomainQ35860974
Nuclear import and cell cycle arrest functions of the HIV-1 Vpr protein are encoded by two separate genes in HIV-2/SIV(SM).Q35914698
The multifactorial nature of HIV-1 latencyQ35935335
Vpx is critical for SIVmne infection of pigtail macaquesQ35965316
Cyclin D3-dependent control of the dNTP pool and HIV-1 replication in human macrophagesQ36186478
Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cellsQ36994727
Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase IIQ37103512
Characterization of Cdk9 T-loop phosphorylation in resting and activated CD4(+) T lymphocytes.Q37429329
G2/M cell cycle arrest correlates with primate lentiviral Vpr interaction with the SLX4 complex.Q38947343
Vpx is required for dissemination and pathogenesis of SIV(SM) PBj: evidence of macrophage-dependent viral amplification.Q39068781
Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1.Q39163475
The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx.Q39405160
Automated genome-wide visual profiling of cellular proteins involved in HIV infectionQ39490430
Establishment of HIV latency in primary CD4+ cells is due to epigenetic transcriptional silencing and P-TEFb restrictionQ39712159
HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome systemQ40121880
Cyclin T1 and CDK9 T-loop phosphorylation are downregulated during establishment of HIV-1 latency in primary resting memory CD4+ T cells.Q42052356
Phosphatase PPM1A negatively regulates P-TEFb function in resting CD4(+) T cells and inhibits HIV-1 gene expressionQ42112998
Gene loss and adaptation to hominids underlie the ancient origin of HIV-1.Q42282750
Sexual Transmission and Propagation of SIV and HIV in Resting and Activated CD4+ T CellsQ57075707
P433issue6
P304page(s)736-740
P577publication date2015-06-01
P1433published inCell Host & MicrobeQ5058153
P1476titleSubversion of Cell Cycle Regulatory Mechanisms by HIV
P478volume17

Reverse relations

cites work (P2860)
Q96350898Conditional expression of HIV-1 Tat in the mouse alters the onset and progression of tonic, inflammatory, and neuropathic hypersensitivity in a sex-dependent manner
Q90440611Differentiation into an Effector Memory Phenotype Potentiates HIV-1 Latency Reversal in CD4+ T Cells
Q60927723Focus on Translation Initiation of the HIV-1 mRNAs
Q26746070HIV Genome-Wide Protein Associations: a Review of 30 Years of Research
Q52577483HIV Tat/P-TEFb Interaction: A Potential Target for Novel Anti-HIV Therapies.
Q47548056Type I Interferon Responses by HIV-1 Infection: Association with Disease Progression and Control
Q64064525Understanding Human-Virus Protein-Protein Interactions Using a Human Protein Complex-Based Analysis Framework
Q40403733miRNA profiling of human naive CD4 T cells links miR-34c-5p to cell activation and HIV replication.

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