scholarly article | Q13442814 |
P50 | author | Fang Zhouzi | Q633818 |
P2093 | author name string | P Wei | |
K A Jones | |||
W H Fischer | |||
S M Fang | |||
M E Garber | |||
P2860 | cites work | Major determinants of the specificity of interaction between small nuclear ribonucleoproteins U1A and U2B'' and their cognate RNAs | Q45188961 |
Pch1(+), a second essential C-type cyclin gene in Schizosaccharomyces pombe. | Q46000120 | ||
Alternative mechanisms of CAK assembly require an assembly factor or an activating kinase | Q46760600 | ||
Purification of P-TEFb, a transcription factor required for the transition into productive elongation. | Q52539193 | ||
Mechanism and regulation of transcriptional elongation and termination by RNA polymerase II | Q63384164 | ||
Human immunodeficiency virus type-1 Tat is an integral component of the activated transcription-elongation complex | Q24568316 | ||
Novel mechanism and factor for regulation by HIV-1 Tat | Q24568366 | ||
The human immunodeficiency virus transactivator Tat interacts with the RNA polymerase II holoenzyme | Q24646774 | ||
Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor | Q24676286 | ||
Crystal structure at 1.92 A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin | Q27730785 | ||
A kinase-cyclin pair in the RNA polymerase II holoenzyme. | Q27930481 | ||
The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex | Q27932742 | ||
Modulation of RNA polymerase II elongation efficiency by C-terminal heptapeptide repeat domain kinase I. | Q27934205 | ||
A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase | Q28247022 | ||
A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer | Q28271385 | ||
Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat | Q28292698 | ||
CDK-independent activation of estrogen receptor by cyclin D1 | Q28304020 | ||
Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexes | Q28304889 | ||
P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro | Q28379179 | ||
TAK, an HIV Tat-associated kinase, is a member of the cyclin-dependent family of protein kinases and is induced by activation of peripheral blood lymphocytes and differentiation of promonocytic cell lines | Q28647556 | ||
Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro | Q29614788 | ||
Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase | Q29614789 | ||
PEST sequences and regulation by proteolysis | Q29616394 | ||
Control of RNA initiation and elongation at the HIV-1 promoter | Q29620157 | ||
Stress and developmental regulation of the yeast C-type cyclin Ume3p (Srb11p/Ssn8p). | Q33887194 | ||
Nuclear translocation and carboxyl-terminal domain phosphorylation of RNA polymerase II delineate the two phases of zygotic gene activation in mammalian embryos | Q34250244 | ||
Two distinct nuclear transcription factors recognize loop and bulge residues of the HIV-1 TAR RNA hairpin | Q34631467 | ||
Synergism between Tat and VP16 in trans-activation of HIV-1 LTR. | Q38313551 | ||
The VP16 transcription activation domain is functional when targeted to a promoter-proximal RNA sequence | Q38324797 | ||
Control of formation of two distinct classes of RNA polymerase II elongation complexes. | Q38329037 | ||
Transfer of Tat and release of TAR RNA during the activation of the human immunodeficiency virus type-1 transcription elongation complex | Q38342881 | ||
Effects of human chromosome 12 on interactions between Tat and TAR of human immunodeficiency virus type 1. | Q40041905 | ||
Juxtaposition between activation and basic domains of human immunodeficiency virus type 1 Tat is required for optimal interactions between Tat and TAR. | Q40045425 | ||
TAR loop-dependent human immunodeficiency virus trans activation requires factors encoded on human chromosome 12. | Q40046655 | ||
RNA-protein interactions. Diverse modes of recognition | Q40401623 | ||
News on initiation and elongation of transcription by RNA polymerase II. | Q40475471 | ||
A weak interaction between the U2A' protein and U2 snRNA helps to stabilize their complex with the U2B" protein | Q40531081 | ||
RNA recognition by the human immunodeficiency virus Tat and Rev proteins | Q40767437 | ||
Does HIV-1 Tat induce a change in viral initiation rights? | Q40905875 | ||
The U2B'' RNP motif as a site of protein-protein interaction. | Q41230779 | ||
Taking a new TAK on tat transactivation | Q41614227 | ||
Specific interaction of the human immunodeficiency virus Tat proteins with a cellular protein kinase. | Q43447901 | ||
High affinity binding of TAR RNA by the human immunodeficiency virus type-1 tat protein requires base-pairs in the RNA stem and amino acid residues flanking the basic region | Q43480910 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | HIV | Q15787 |
P304 | page(s) | 451-62 | |
P577 | publication date | 1998-02-20 | |
P1433 | published in | Cell | Q655814 |
P1476 | title | A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA | |
P478 | volume | 92 |
Q33631612 | 17β-estradiol protects primary macrophages against HIV infection through induction of interferon-alpha |
Q34723651 | 7SK small nuclear RNA directly affects HMGA1 function in transcription regulation |
Q24634280 | 7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcription |
Q30438975 | 9-Aminoacridine inhibition of HIV-1 Tat dependent transcription |
Q27765139 | A 1.3-A resolution crystal structure of the HIV-1 trans-activation response region RNA stem reveals a metal ion-dependent bulge conformation |
Q40740441 | A Network of Regulations by Small Non-Coding RNAs: The P-TEFb Kinase in Development and Pathology |
Q33793854 | A Pipeline for Drug Target Identification and Validation |
Q30274626 | A Role of RNA Helicase A in cis-Acting Transactivation Response Element-mediated Transcriptional Regulation of Human Immunodeficiency Virus Type 1. |
Q34139815 | A bimolecular mechanism of HIV-1 Tat protein interaction with RNA polymerase II transcription elongation complexes |
Q33802821 | A block to human immunodeficiency virus type 1 assembly in murine cells |
Q29547180 | A chromatin landmark and transcription initiation at most promoters in human cells |
Q45606075 | A conditionally replicating virus as a novel approach toward an HIV vaccine |
Q40256942 | A high-throughput drug screening system for HIV-1 transcription inhibitors |
Q28216031 | A highly purified RNA polymerase II elongation control system |
Q24561968 | A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb |
Q24302596 | A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat. |
Q39685470 | A minimal chimera of human cyclin T1 and tat binds TAR and activates human immunodeficiency virus transcription in murine cells. |
Q35155254 | A naturally occurring substitution in human immunodeficiency virus Tat increases expression of the viral genome |
Q24804709 | A new paradigm in eukaryotic biology: HIV Tat and the control of transcriptional elongation |
Q28190014 | A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter |
Q40195173 | A novel anticancer agent ARC antagonizes HIV-1 and HCV. |
Q42689207 | A novel long distance base-pairing interaction in human immunodeficiency virus type 1 RNA occludes the Gag start codon |
Q34391750 | A nucleolar TAR decoy inhibitor of HIV-1 replication. |
Q35107224 | A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cells |
Q40249131 | A phenotypic recessive, post-entry block in rabbit cells that results in aberrant trafficking of HIV-1. |
Q30479706 | A real-time view of the TAR:Tat:P-TEFb complex at HIV-1 transcription sites |
Q34621011 | A role for CDK9-cyclin K in maintaining genome integrity |
Q30321811 | A second-site mutation that restores replication of a Tat-defective human immunodeficiency virus |
Q42039736 | A single point mutation in cyclin T1 eliminates binding to Hexim1, Cdk9 and RNA but not to AFF4 and enforces repression of HIV transcription |
Q27334977 | A single-molecule view of transcription reveals convoys of RNA polymerases and multi-scale bursting |
Q29616120 | A third-generation lentivirus vector with a conditional packaging system |
Q27930899 | A yeast heterogeneous nuclear ribonucleoprotein complex associated with RNA polymerase II |
Q41172835 | AF4 and AF4N protein complexes: recruitment of P-TEFb kinase, their interactome and potential functions |
Q27683845 | AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter |
Q34052968 | APOBEC3G inhibits HIV-1 RNA elongation by inactivating the viral trans-activation response element |
Q28203240 | Accumulation of high levels of the p53 and p130 growth-suppressing proteins in cell lines stably over-expressing cyclin-dependent kinase 6 (cdk6) |
Q44530421 | Acetylation of Tat defines a cyclinT1-independent step in HIV transactivation |
Q24310643 | Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription |
Q24318644 | Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells |
Q24548503 | Acetylation of histones and transcription-related factors |
Q63351469 | Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activity |
Q28375916 | Acridone derivatives are selective inhibitors of HIV-1 replication in chronically infected cells |
Q63351215 | Activating Latent HIV by Inhibiting Bromodomain Proteins |
Q34005293 | Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1). |
Q28115623 | Activation of MyoD-dependent transcription by cdk9/cyclin T2 |
Q35746236 | Activation of P-TEFb at sites of dual HIV/TB infection, and inhibition of MTB-induced HIV transcriptional activation by the inhibitor of CDK9, Indirubin-3'-monoxime |
Q39606992 | Activation of human immunodeficiency virus transcription in T cells revisited: NF-kappaB p65 stimulates transcriptional elongation |
Q27936458 | Activation of the cyclin-dependent kinase CTDK-I requires the heterodimerization of two unstable subunits |
Q44040788 | Amino acid modification in the HIV-1 Tat basic domain: insights from molecular dynamics and in vivo functional studies. |
Q33930664 | An HIV-1 transgenic rat that develops HIV-related pathology and immunologic dysfunction |
Q43634596 | An RNA-binding chameleon |
Q34289422 | An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tat-dependent HIV transcription |
Q38163449 | An integrated overview of HIV-1 latency |
Q53615854 | Analysis of U1 small nuclear RNA interaction with cyclin H. |
Q33221255 | Analysis of p300 acetyltransferase substrate specificity by MALDI TOF mass spectrometry |
Q24527261 | Analysis of the effect of natural sequence variation in Tat and in cyclin T on the formation and RNA binding properties of Tat-cyclin T complexes |
Q28257440 | Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186 |
Q36632210 | Anti-viral opportunities during transcriptional activation of latent HIV in the host chromatin |
Q33836069 | Antiapoptotic function of Cdk9 (TAK/P-TEFb) in U937 promonocytic cells |
Q73138904 | Antibodies to Tat and Vpr in the GRIV cohort: differential association with maintenance of long-term non-progression status in HIV-1 infection |
Q42796349 | Antisense RNA sequences targeting the 5' leader packaging signal region of human immunodeficiency virus type-1 inhibits viral replication at post-transcriptional stages of the life cycle |
Q28292152 | Antiviral activity of CYC202 in HIV-1-infected cells |
Q37410634 | Arginine methylation increases the stability of human immunodeficiency virus type 1 Tat. |
Q24672150 | Arginine methylation of the human immunodeficiency virus type 1 Tat protein by PRMT6 negatively affects Tat Interactions with both cyclin T1 and the Tat transactivation region |
Q38906287 | As(2)O(3) enhances retroviral reverse transcription and counteracts Ref1 antiviral activity |
Q41641646 | BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism. |
Q24337878 | BRCA1 cooperates with NUFIP and P-TEFb to activate transcription by RNA polymerase II |
Q35177820 | BRCA1 functions as a novel transcriptional cofactor in HIV-1 infection |
Q27933584 | BUR1 and BUR2 encode a divergent cyclin-dependent kinase-cyclin complex important for transcription in vivo |
Q39591738 | Binding of Tat to TAR and recruitment of positive transcription elongation factor b occur independently in bovine immunodeficiency virus |
Q24563382 | Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor |
Q40563544 | Bis-anthracycline antibiotics inhibit human immunodeficiency virus type 1 transcription |
Q36777646 | Bovine HEXIM1 inhibits bovine immunodeficiency virus replication through regulating BTat-mediated transactivation |
Q28240747 | Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation |
Q37586824 | Brd4 and HEXIM1: multiple roles in P-TEFb regulation and cancer |
Q28209708 | Bromodomain: an acetyl-lysine binding domain |
Q28143301 | C-terminal domain phosphatase sensitivity of RNA polymerase II in early elongation complexes on the HIV-1 and adenovirus 2 major late templates |
Q34353412 | CD4-specific transgenic expression of human cyclin T1 markedly increases human immunodeficiency virus type 1 (HIV-1) production by CD4+ T lymphocytes and myeloid cells in mice transgenic for a provirus encoding a monocyte-tropic HIV-1 isolate |
Q35780509 | CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo |
Q24550765 | CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA |
Q42812732 | CDK9 has the intrinsic property to shuttle between nucleus and cytoplasm, and enhanced expression of cyclin T1 promotes its nuclear localization |
Q39429987 | CDK9/cyclin complexes modulate endoderm induction by direct interaction with Mix.3/mixer. |
Q59352420 | CDK9: a signaling hub for transcriptional control |
Q34806667 | CTD phosphatase: role in RNA polymerase II cycling and the regulation of transcript elongation |
Q41935503 | CTGC motifs within the HIV core promoter specify Tat-responsive pre-initiation complexes |
Q37068686 | CTIP2 is a negative regulator of P-TEFb |
Q37740906 | CYCLINg through transcription: posttranslational modifications of P-TEFb regulate transcription elongation |
Q35067664 | Cap-binding protein complex links pre-mRNA capping to transcription elongation and alternative splicing through positive transcription elongation factor b (P-TEFb) |
Q36943400 | Capsid-dependent and -independent postentry restriction of primate lentivirus tropism in rodent cells |
Q39163015 | Cdk9 phosphorylates Pirh2 protein and prevents degradation of p53 protein |
Q40696536 | Cdk9, a member of the cdc2-like family of kinases, binds to gp130, the receptor of the IL-6 family of cytokines |
Q40375877 | Cell-dependent interference of a series of new 6-aminoquinolone derivatives with viral (HIV/CMV) transactivation |
Q39002029 | Cell-free entry of human T-cell leukemia virus type 1 to mouse cells |
Q33347964 | Cell-type-specific proteome and interactome: using HIV-1 Tat as a test case |
Q34465453 | Cellular gene expression upon human immunodeficiency virus type 1 infection of CD4(+)-T-cell lines |
Q33302108 | Cellular mRNA activates transcription elongation by displacing 7SK RNA. |
Q41818257 | Characterization of HIV Tat modifications using novel methyl-lysine-specific antibodies |
Q40806871 | Characterization of HIV-1 Tat proteins mutated in the transactivation domain for prophylactic and therapeutic application. |
Q106453199 | Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor |
Q48910832 | Characterization of a novel cdk1-related kinase |
Q35219724 | Characterization of resistance to rhabdovirus and retrovirus infection in a human myeloid cell line |
Q39548930 | Characterization of the Jembrana disease virus tat gene and the cis- and trans-regulatory elements in its long terminal repeats. |
Q34283463 | Characterization of the influence of mediator complex in HIV-1 transcription |
Q34714816 | Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy |
Q36078954 | Chemicals that footprint DNA: hitting HIV-1 in the minor groove |
Q27021127 | Chromatin, non-coding RNAs, and the expression of HIV |
Q38333164 | Closing loop base pairs in RNA loop-loop complexes: structural behavior, interaction energy and solvation analysis through molecular dynamics simulations |
Q35894061 | Cocaine promotes both initiation and elongation phase of HIV-1 transcription by activating NF-κB and MSK1 and inducing selective epigenetic modifications at HIV-1 LTR |
Q34408367 | Combinatorial Synthesis, Screening, and Binding Studies of Highly Functionalized Polyamino-amido Oligomers for Binding to Folded RNA. |
Q43564279 | Comparative Analysis of Tat-Dependent and Tat-Deficient Natural Lentiviruses |
Q35580831 | Comparative Pathogenesis of Epsilonretroviruses |
Q37417688 | Comparative functional analysis of Jembrana disease virus Tat protein on lentivirus long terminal repeat promoters: evidence for flexibility at its N-terminus |
Q24796929 | Comparative genomics of cyclin-dependent kinases suggest co-evolution of the RNAP II C-terminal domain and CTD-directed CDKs |
Q35920526 | Complex effects of flavopiridol on the expression of primary response genes |
Q33418619 | Computational identification of protein methylation sites through bi-profile Bayes feature extraction |
Q38800411 | Conditional Cytotoxic Anti-HIV Gene Therapy for Selectable Cell Modification |
Q54050438 | Conditional expression of RNA polymerase II in mammalian cells. Deletion of the carboxyl-terminal domain of the large subunit affects early steps in transcription. |
Q36099319 | Construction of a doxycycline-dependent simian immunodeficiency virus reveals a nontranscriptional function of tat in viral replication. |
Q37972643 | Control of HIV latency by epigenetic and non-epigenetic mechanisms |
Q41941777 | Control of Transcriptional Elongation by RNA Polymerase II: A Retrospective |
Q28646668 | Control of elongation by RNA polymerase II |
Q33398516 | Control of stochastic gene expression by host factors at the HIV promoter |
Q33728518 | Controlling cellular P-TEFb activity by the HIV-1 transcriptional transactivator Tat |
Q40863490 | Cooperative interaction between HIV-1 regulatory proteins Tat and Vpr modulates transcription of the viral genome |
Q30603666 | Cooperativity among Rev-associated nuclear export signals regulates HIV-1 gene expression and is a determinant of virus species tropism |
Q24559797 | Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription |
Q28276848 | Cracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFb |
Q40238292 | Cross-interaction between JC virus agnoprotein and human immunodeficiency virus type 1 (HIV-1) Tat modulates transcription of the HIV-1 long terminal repeat in glial cells |
Q28236516 | Crystal structure of CC3 (TIP30): implications for its role as a tumor suppressor |
Q27683254 | Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4 |
Q37645582 | Curing HIV: Pharmacologic approaches to target HIV-1 latency |
Q89620873 | Current Status of Latency Reversing Agents Facing the Heterogeneity of HIV-1 Cellular and Tissue Reservoirs |
Q38973362 | Current views on HIV-1 latency, persistence, and cure. |
Q27645094 | Cyclin Box Structure of the P-TEFb Subunit Cyclin T1 Derived from a Fusion Complex with EIAV Tat |
Q28137611 | Cyclin C/CDK8 and cyclin H/CDK7/p36 are biochemically distinct CTD kinases |
Q28579106 | Cyclin D3/CDK11(p58) complex involved in Schwann cells proliferation repression caused by lipopolysaccharide |
Q33567848 | Cyclin F/FBXO1 Interacts with HIV-1 Viral Infectivity Factor (Vif) and Restricts Progeny Virion Infectivity by Ubiquitination and Proteasomal Degradation of Vif Protein through SCFcyclin F E3 Ligase Machinery |
Q52543313 | Cyclin G1 is involved in G2/M arrest in response to DNA damage and in growth control after damage recovery. |
Q28138707 | Cyclin K functions as a CDK9 regulatory subunit and participates in RNA polymerase II transcription |
Q38003504 | Cyclin K goes with Cdk12 and Cdk13 |
Q42052356 | Cyclin T1 and CDK9 T-loop phosphorylation are downregulated during establishment of HIV-1 latency in primary resting memory CD4+ T cells. |
Q39681689 | Cyclin T1 expression is mediated by a complex and constitutively active promoter and does not limit human immunodeficiency virus type 1 Tat function in unstimulated primary lymphocytes |
Q34582060 | Cyclin T1 overexpression induces malignant transformation and tumor growth |
Q33367106 | Cyclin T1-dependent genes in activated CD4 T and macrophage cell lines appear enriched in HIV-1 co-factors |
Q35805077 | Cyclin dependent kinase 11 in RNA transcription and splicing |
Q54216878 | Cyclin-dependent kinase 7 (CDK7)-mediated phosphorylation of the CDK9 activation loop promotes P-TEFb assembly with Tat and proviral HIV reactivation. |
Q35038779 | Cyclin-dependent kinases as new targets for the prevention and treatment of cancer |
Q41138339 | DDX6 transfers P-TEFb kinase to the AF4/AF4N (AFF1) super elongation complex |
Q30672419 | DNA aptamers selected against the HIV-1 trans-activation-responsive RNA element form RNA-DNA kissing complexes |
Q28139929 | DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation |
Q35911735 | Dark matter RNA: an intelligent scaffold for the dynamic regulation of the nuclear information landscape |
Q37487966 | Defining NELF-E RNA binding in HIV-1 and promoter-proximal pause regions |
Q34267043 | Defining differential genetic signatures in CXCR4- and the CCR5-utilizing HIV-1 co-linear sequences |
Q41175211 | Destabilization of the TAR hairpin affects the structure and function of the HIV-1 leader RNA. |
Q42004076 | Destabilization of the TAR hairpin leads to extension of the polyA hairpin and inhibition of HIV-1 polyadenylation. |
Q32173424 | Development of cyclin-dependent kinase modulators as novel therapeutic approaches for hematological malignancies |
Q40817567 | Development of disabled, replication-defective gene transfer vectors from the Jembrana disease virus, a new infectious agent of cattle |
Q24684924 | Developmental regulators containing the I-mfa domain interact with T cyclins and Tat and modulate transcription |
Q36296748 | Differences in NMDA receptor expression during human development determine the response of neurons to HIV-tat-mediated neurotoxicity |
Q39693187 | Differential acetylation of Tat coordinates its interaction with the co-activators cyclin T1 and PCAF |
Q40642204 | Differential activation of Tat variants in mitogen-stimulated cells: implications for HIV-1 postintegration latency |
Q41789287 | Differential chromatin looping regulates CD4 expression in immature thymocytes |
Q33819734 | Diminished rev-mediated stimulation of human immunodeficiency virus type 1 protein synthesis is a hallmark of human astrocytes |
Q36419687 | Direct inhibition of CDK9 blocks HIV-1 replication without preventing T-cell activation in primary human peripheral blood lymphocytes |
Q24293249 | Direct interaction of the human I-mfa domain-containing protein, HIC, with HIV-1 Tat results in cytoplasmic sequestration and control of Tat activity |
Q38739211 | Distinct conformational transition patterns of noncoding 7SK snRNA and HIV TAR RNAs upon Tat binding |
Q44264374 | Distinct regions of cyclinT1 are required for binding to CDK9 and for recruitment to the HIV-1 Tat/TAR complex. |
Q34816193 | Diversity of acetylation targets and roles in transcriptional regulation: the human immunodeficiency virus type 1 promoter as a model system |
Q24554258 | Domains in the SPT5 protein that modulate its transcriptional regulatory properties |
Q41320056 | Dominant negative mutant cyclin T1 proteins inhibit HIV transcription by specifically degrading Tat. |
Q28202607 | Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin |
Q36555327 | Dose-response resistance to HIV-1/MuLV pseudotype virus ex vivo in a hairpin ribozyme transgenic mouse model |
Q55314057 | Downregulation of microRNA-142-3p and its tumor suppressor role in gastric cancer. |
Q40024356 | Drosophila Pgc protein inhibits P-TEFb recruitment to chromatin in primordial germ cells |
Q35128809 | Dynamic transcriptional events in embryonic stem cells mediated by the super elongation complex (SEC). |
Q28646726 | Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element |
Q38756296 | Dynamics of nascent mRNA folding and RNA-protein interactions: an alternative TAR RNA structure is involved in the control of HIV-1 mRNA transcription |
Q34404828 | Early emergence and selection of a SIV-LTR C/EBP site variant in SIV-infected macaques that increases virus infectivity |
Q40945385 | Effect of Cocaine on Pulmonary Vascular Remodeling and Hemodynamics in Human Immunodeficiency Virus-Transgenic Rats |
Q35040154 | Effect of SWI/SNF chromatin remodeling complex on HIV-1 Tat activated transcription |
Q39549994 | Effect of transcription peptide inhibitors on HIV-1 replication |
Q35075250 | Effect on HIV-1 gene expression, Tat-Vpr interaction and cell apoptosis by natural variants of HIV-1 Tat exon 1 and Vpr from Northern India |
Q37409631 | Effects of conditional central expression of HIV-1 tat protein to potentiate cocaine-mediated psychostimulation and reward among male mice |
Q33953076 | Efficient assembly of an HIV-1/MLV Gag-chimeric virus in murine cells |
Q34510011 | Efficient in silico exploration of RNA interhelical conformations using Euler angles and WExplore |
Q41859093 | Efficient transcription of the EBER2 gene depends on the structural integrity of the RNA. |
Q39668496 | Endogenous CD317/Tetherin limits replication of HIV-1 and murine leukemia virus in rodent cells and is resistant to antagonists from primate viruses. |
Q34877762 | Epigenetic heterogeneity in HIV-1 latency establishment |
Q39933477 | Epigenetic silencing of human immunodeficiency virus (HIV) transcription by formation of restrictive chromatin structures at the viral long terminal repeat drives the progressive entry of HIV into latency |
Q35252186 | Eradicating HIV-1 infection: seeking to clear a persistent pathogen |
Q42068689 | Evidence for a base triple in the free HIV-1 TAR RNA. |
Q42831352 | Evidence for conformational flexibility in the Tat-TAR recognition motif of cyclin T1. |
Q22008559 | Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro |
Q28742565 | Evolution of a species-specific determinant within human CRM1 that regulates the post-transcriptional phases of HIV-1 replication |
Q39549399 | Evolution of the human immunodeficiency virus type 1 long terminal repeat promoter by conversion of an NF-kappaB enhancer element into a GABP binding site. |
Q35462419 | Evolutionary distance of amino acid sequence orthologs across macaque subspecies: identifying candidate genes for SIV resistance in Chinese rhesus macaques |
Q33866139 | Exchange of the basic domain of human immunodeficiency virus type 1 Rev for a polyarginine stretch expands the RNA binding specificity, and a minimal arginine cluster is required for optimal RRE RNA binding affinity, nuclear accumulation, and trans- |
Q40676905 | Exosome-associated release, uptake, and neurotoxicity of HIV-1 Tat protein. |
Q36466170 | Exosomes from HIV-1-infected Cells Stimulate Production of Pro-inflammatory Cytokines through Trans-activating Response (TAR) RNA |
Q38702490 | Exosomes from uninfected cells activate transcription of latent HIV-1. |
Q37369645 | Exploiting features of adenovirus replication to support mammalian kinase production |
Q31068120 | Expression of Arabidopsis SR-like splicing proteins confers salt tolerance to yeast and transgenic plants |
Q37209394 | Expression of Human CD4 and chemokine receptors in cotton rat cells confers permissiveness for productive HIV infection. |
Q33707390 | Expression of glucose transporter 1 confers susceptibility to human T-cell leukemia virus envelope-mediated fusion |
Q36283854 | FACT Proteins, SUPT16H and SSRP1, Are Transcriptional Suppressors of HIV-1 and HTLV-1 That Facilitate Viral Latency |
Q22003918 | FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO |
Q91959762 | Face-time with TAR: Portraits of an HIV-1 RNA with diverse modes of effector recognition relevant for drug discovery |
Q28585216 | Failure to proliferate and mitotic arrest of CDK11(p110/p58)-null mutant mice at the blastocyst stage of embryonic cell development |
Q41741183 | Fitting peptides into the RNA world |
Q34082542 | Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo |
Q33910799 | Flavopiridol inhibits P-TEFb and blocks HIV-1 replication |
Q33832656 | Flavopiridol: the first cyclin-dependent kinase inhibitor in human clinical trials |
Q45316602 | Formation of HIV-1 elongation complex containing HIV-1 Tat |
Q84044756 | Formation of Tat-TAR containing ribonucleoprotein complexes for biochemical and structural analyses |
Q50289424 | Formation of the P-TEFb(Cyclin T1:Cdk9) complex |
Q39395490 | Functional characterization of a human cyclin T1 mutant reveals a different binding surface for Tat and HEXIM1. |
Q39591095 | Functional differences between human and bovine immunodeficiency virus Tat transcription factors |
Q39590547 | Functional differences between the long terminal repeat transcriptional promoters of human immunodeficiency virus type 1 subtypes A through G. |
Q33654155 | Functional domains of Tat required for efficient human immunodeficiency virus type 1 reverse transcription. |
Q37368973 | Functional evolution of cyclin-dependent kinases. |
Q54762582 | Functional inactivation of Cdk9 through oligomerization chain reaction. |
Q42513599 | Functional interaction between cyclin T1/cdk9 and Puralpha determines the level of TNFalpha promoter activation by Tat in glial cells |
Q28140346 | Functional interaction between the HIV transactivator Tat and the transcriptional coactivator PC4 in T cells |
Q39550602 | Functional interactions between herpesvirus oncoprotein MEQ and cell cycle regulator CDK2. |
Q34869767 | G-actin participates in RNA polymerase II-dependent transcription elongation by recruiting positive transcription elongation factor b (P-TEFb). |
Q36071452 | Gene activity in primary T cells infected with HIV89.6: intron retention and induction of genomic repeats. |
Q33936233 | Gene expression changes consistent with neuroAIDS and impaired working memory in HIV-1 transgenic rats. |
Q35842547 | Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription |
Q33947277 | Genetic analysis of the structure and function of 7SK small nuclear ribonucleoprotein (snRNP) in cells |
Q35207524 | Genetic therapy for HIV/AIDS. |
Q92135927 | Genetic variation and function of the HIV-1 Tat protein |
Q34991865 | Genetically-modified-animal models for human infections: the Listeria paradigm |
Q42755157 | Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription. |
Q45869361 | Genomic organization and characterization of promoter function of the human CDK9 gene |
Q40470271 | Granulin and granulin repeats interact with the Tat.P-TEFb complex and inhibit Tat transactivation. |
Q46689072 | HDAC1/NFκB pathway is involved in curcumin inhibiting of Tat-mediated long terminal repeat transactivation |
Q35829330 | HEXIM1 is a promiscuous double-stranded RNA-binding protein and interacts with RNAs in addition to 7SK in cultured cells. |
Q37226490 | HEXIM1, a New Player in the p53 Pathway |
Q58612091 | HEXIM1-Tat chimera inhibits HIV-1 replication |
Q24294998 | HEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SK |
Q26746070 | HIV Genome-Wide Protein Associations: a Review of 30 Years of Research |
Q35088029 | HIV Tat, its TARgets and the control of viral gene expression |
Q52577483 | HIV Tat/P-TEFb Interaction: A Potential Target for Novel Anti-HIV Therapies. |
Q34935285 | HIV and hepatitis delta virus: evolution takes different paths to relieve blocks in transcriptional elongation |
Q37974218 | HIV latency |
Q40361663 | HIV latency: present knowledge, future directions |
Q78128370 | HIV recent advances in AIDS research: genetics, molecular biology and immunology |
Q26995784 | HIV restriction in quiescent CD4⁺ T cells |
Q33292300 | HIV-1 TAR RNA enhances the interaction between Tat and cyclin T1. |
Q40352274 | HIV-1 TAT represses transcription of the bone morphogenic protein receptor-2 in U937 monocytic cells |
Q39134277 | HIV-1 Tat and Viral Latency: What We Can Learn from Naturally Occurring Sequence Variations. |
Q34896128 | HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription |
Q39703646 | HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP |
Q37518169 | HIV-1 Tat directly binds to NFkappaB enhancer sequence: role in viral and cellular gene expression |
Q24564896 | HIV-1 Tat enters T cells using coated pits before translocating from acidified endosomes and eliciting biological responses |
Q40016960 | HIV-1 Tat inhibits NGF-induced Egr-1 transcriptional activity and consequent p35 expression in neural cells |
Q44061963 | HIV-1 Tat interaction with RNA polymerase II C-terminal domain (CTD) and a dynamic association with CDK2 induce CTD phosphorylation and transcription from HIV-1 promoter |
Q41675687 | HIV-1 Tat interacts with cyclin T1 to direct the P-TEFb CTD kinase complex to TAR RNA. |
Q33940354 | HIV-1 Tat protein interacts with mammalian capping enzyme and stimulates capping of TAR RNA. |
Q30436450 | HIV-1 Tat protein suppresses cholangiocyte toll-like receptor 4 expression and defense against Cryptosporidium parvum |
Q28215081 | HIV-1 Tat protein-mediated transactivation of the HIV-1 long terminal repeat promoter is potentiated by a novel nuclear Tat-interacting protein of 110 kDa, Tip110 |
Q40727461 | HIV-1 Tat-associated RNA polymerase C-terminal domain kinase, CDK2, phosphorylates CDK7 and stimulates Tat-mediated transcription |
Q42767857 | HIV-1 Tat: Its Dependence on Host Factors is Crystal Clear |
Q33711447 | HIV-1 Tat: coping with negative elongation factors |
Q47555826 | HIV-1 Vif's capacity to manipulate the cell cycle is species-specific |
Q47964324 | HIV-1 auxiliary proteins: making connections in a dying cell |
Q21245215 | HIV-1 gene expression: lessons from provirus and non-integrated DNA |
Q38204866 | HIV-1 latency: an update of molecular mechanisms and therapeutic strategies |
Q35166833 | HIV-1 pathogenesis |
Q37607912 | HIV-1 regulation of latency in the monocyte-macrophage lineage and in CD4+ T lymphocytes |
Q38273477 | HIV-1 replication and latency are regulated by translational control of cyclin T1 |
Q22007982 | HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter |
Q77891434 | HIV-1 transcription: activation mediated by acetylation of Tat |
Q51981129 | HIV-1 transgenic rat CD4+ T cells develop decreased CD28 responsiveness and suboptimal Lck tyrosine dephosphorylation following activation. |
Q36407266 | HIV-1-Tat Protein Inhibits SC35-mediated Tau Exon 10 Inclusion through Up-regulation of DYRK1A Kinase. |
Q36901782 | HMGA1 directly interacts with TAR to modulate basal and Tat-dependent HIV transcription |
Q27469600 | Hepatitis C virus internal ribosome entry site (IRES) stem loop IIId contains a phylogenetically conserved GGG triplet essential for translation and IRES folding |
Q45395775 | Hexamethylbisacetamide and disruption of human immunodeficiency virus type 1 latency in CD4(+) T cells |
Q35058535 | Hide, shield and strike back: how HIV-infected cells avoid immune eradication |
Q34291018 | High natural permissivity of primary rabbit cells for HIV-1, with a virion infectivity defect in macrophages as the final replication barrier |
Q38808207 | High-Throughput Humanized Mouse Models for Evaluation of HIV-1 Therapeutics and Pathogenesis. |
Q39446082 | Highly divergent lentiviral Tat proteins activate viral gene expression by a common mechanism |
Q38357741 | Histone deacetylase 6 in health and disease |
Q37086989 | Host Double Strand Break Repair Generates HIV-1 Strains Resistant to CRISPR/Cas9. |
Q59357225 | Host and Viral Factors Influencing Interplay between the Macrophage and HIV-1 |
Q33455551 | Host cell factors in HIV replication: meta-analysis of genome-wide studies |
Q36390969 | Host-cell positive transcription elongation factor b kinase activity is essential and limiting for HIV type 1 replication |
Q28243562 | Hsp90: a chaperone for HIV-1 |
Q36363829 | Human CRM1 augments production of infectious human and feline immunodeficiency viruses from murine cells |
Q24307731 | Human DDX3 interacts with the HIV-1 Tat protein to facilitate viral mRNA translation |
Q33850701 | Human GLI-2 is a tat activation response element-independent Tat cofactor |
Q40967217 | Human T-cell leukemia virus type 1 can infect a wide variety of cells in mice |
Q39629705 | Human TOP1 residues implicated in species specificity of HIV-1 infection are required for interaction with BTBD2, and RNAi of BTBD2 in old world monkey and human cells increases permissiveness to HIV-1 infection |
Q89522955 | Human Tat-specific factor 1 binds the HIV-1 genome and selectively transports HIV-1 RNAs |
Q33815080 | Human and rodent transcription elongation factor P-TEFb: interactions with human immunodeficiency virus type 1 tat and carboxy-terminal domain substrate |
Q33825196 | Human anti-HIV-1 tat sFv intrabodies for gene therapy of advanced HIV-1-infection and AIDS. |
Q34545610 | Human chromosome 2 carries a gene required for production of infectious human immunodeficiency virus type 1. |
Q42829649 | Human cyclin C protein is stabilized by its associated kinase cdk8, independently of its catalytic activity |
Q43193366 | Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo. |
Q36330062 | Human immunodeficiency virus (HIV) latency: the major hurdle in HIV eradication |
Q33863026 | Human immunodeficiency virus Tat associates with a specific set of cellular RNAs |
Q33809273 | Human immunodeficiency virus and AIDS: insights from animal lentiviruses |
Q33541775 | Human immunodeficiency virus gene regulation as a target for antiviral chemotherapy. |
Q24564662 | Human immunodeficiency virus type 1 Tat increases the expression of cleavage and polyadenylation specificity factor 73-kilodalton subunit modulating cellular and viral expression |
Q40004324 | Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation |
Q39612144 | Human immunodeficiency virus type 1 Vif protein is an integral component of an mRNP complex of viral RNA and could be involved in the viral RNA folding and packaging process |
Q45723766 | Human immunodeficiency virus type 1 envelope-mediated neuropathogenesis: targeted gene delivery by a Sindbis virus expression vector |
Q41039158 | Human immunodeficiency virus type 1 infection induces cyclin T1 expression in macrophages. |
Q39685140 | Human immunodeficiency virus type 1 nucleocapsid protein nuclear localization mediates early viral mRNA expression |
Q40679108 | Human immunodeficiency virus type 1 subtype C exhibits higher transactivation activity of Tat than subtypes B and E. |
Q39595632 | Human immunodeficiency virus type 1 tat protein activates transcription factor NF-kappaB through the cellular interferon-inducible, double-stranded RNA-dependent protein kinase, PKR |
Q35906138 | Human immunodeficiency virus-1 Tat activates NF-κB via physical interaction with IκB-α and p65. |
Q24310867 | Human mediator subunit MED26 functions as a docking site for transcription elongation factors |
Q35168345 | Human topoisomerase I promotes HIV-1 proviral DNA synthesis: implications for the species specificity and cellular tropism of HIV-1 infection. |
Q56795003 | Identification of Limiting Steps for Efficient Trans-activation of HIV-1 Promoter by Tat inSaccharomyces cerevisiae |
Q39611074 | Identification of a cellular protein that interacts and synergizes with the RTA (ORF50) protein of Kaposi's sarcoma-associated herpesvirus in transcriptional activation |
Q28247078 | Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat |
Q24317025 | Identification of multiple cyclin subunits of human P-TEFb |
Q41457054 | Identification of novel inhibitors against Cyclin Dependent Kinase 9/Cyclin T1 complex as: Anti cancer agent |
Q34527341 | Identification of novel inhibitors of human immunodeficiency virus type 1 replication by in silico screening targeting cyclin T1/Tat interaction |
Q37034627 | Identification of potential drug targets using genomics and proteomics: a systems approach |
Q38714324 | Imaging HIV-1 Genomic DNA from Entry through Productive Infection |
Q26782046 | Impact of Chromatin on HIV Replication |
Q36148507 | Impact of Tat Genetic Variation on HIV-1 Disease |
Q40541599 | Imperatorin inhibits HIV-1 replication through an Sp1-dependent pathway |
Q36805433 | Improving HIV proteome annotation: new features of BioAfrica HIV Proteomics Resource |
Q52808328 | In cell mutational interference mapping experiment (in cell MIME) identifies the 5' polyadenylation signal as a dual regulator of HIV-1 genomic RNA production and packaging. |
Q28211352 | In vitro evidence for a long range pseudoknot in the 5'-untranslated and matrix coding regions of HIV-1 genomic RNA |
Q38291138 | In vitro evidence that the untranslated leader of the HIV-1 genome is an RNA checkpoint that regulates multiple functions through conformational changes |
Q39324883 | In vitro susceptibility to infection with SIVcpz and HIV-1 is lower in chimpanzee than in human peripheral blood mononuclear cells |
Q35066359 | In vivo SELEX of single-stranded domains in the HIV-1 leader RNA. |
Q30439541 | Inability of human immunodeficiency virus type 1 produced in murine cells to selectively incorporate primer formula |
Q42554535 | Indirubin 3'-monoxime, from a Chinese traditional herbal formula, suppresses viremia in humanized mice infected with multidrug-resistant HIV |
Q40414692 | Induction of OGG1 gene expression by HIV-1 Tat. |
Q33849629 | Induction of TAK (cyclin T1/P-TEFb) in purified resting CD4(+) T lymphocytes by combination of cytokines |
Q21245103 | Infection by agnoprotein-negative mutants of polyomavirus JC and SV40 results in the release of virions that are mostly deficient in DNA content |
Q35073696 | Inflammatory papillomatous hyperplasia and epidermal necrosis in a transgenic rat for HIV-1. |
Q35192970 | Inhibition of HIV-1 Tat-mediated transcription by a coumarin derivative, BPRHIV001, through the Akt pathway. |
Q77219939 | Inhibition of HIV-1 replication by anti-trans-activation responsive polyamide nucleotide analog |
Q53909022 | Inhibition of HIV-1 replication by cell-penetrating peptides binding Rev. |
Q36850296 | Inhibition of HIV-1 transcription and replication by a newly identified cyclin T1 splice variant. |
Q45049610 | Inhibition of HIV-1 virus replication using small soluble Tat peptides |
Q24298519 | Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA |
Q36915824 | Inhibition of Tat-mediated HIV-1 replication and neurotoxicity by novel GSK3-beta inhibitors |
Q31115718 | Inhibition of Tat-mediated transactivation and HIV-1 replication by human anti-hCyclinT1 intrabodies |
Q28478188 | Inhibition of both HIV-1 reverse transcription and gene expression by a cyclic peptide that binds the Tat-transactivating response element (TAR) RNA |
Q35036496 | Inhibition of human T cell leukemia virus type 2 replication by the suppressive action of class II transactivator and nuclear factor Y. |
Q36954414 | Inhibition of human immunodeficiency virus type 1 replication by RNA interference directed against human transcription elongation factor P-TEFb (CDK9/CyclinT1). |
Q39470193 | Inhibition of human immunodeficiency virus type 1 replication by combination of transcription inhibitor K-12 and other antiretroviral agents in acutely and chronically infected cells |
Q28343602 | Inhibition of human immunodeficiency virus type 1 replication in acutely and chronically infected cells by EM2487, a novel substance produced by a Streptomyces species |
Q28344365 | Inhibition of human immunodeficiency virus type 1 transcription by chemical cyclin-dependent kinase inhibitors |
Q33780297 | Inhibition of human immunodeficiency virus type-1 by cdk inhibitors |
Q39139534 | Inhibitory function of adapter-related protein complex 2 alpha 1 subunit in the process of nuclear translocation of human immunodeficiency virus type 1 genome |
Q37354566 | Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex |
Q39676027 | Interaction between P-TEFb and the C-terminal domain of RNA polymerase II activates transcriptional elongation from sites upstream or downstream of target genes |
Q24548261 | Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome |
Q33890579 | Interaction of HIV-1 Tat with Puralpha in nuclei of human glial cells: characterization of RNA-mediated protein-protein binding |
Q39601983 | Interaction of JC virus agno protein with T antigen modulates transcription and replication of the viral genome in glial cells |
Q73408185 | Interaction of Sp1 transcription factor with HIV-1 Tat protein: looking for cellular partners |
Q39581386 | Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein |
Q38358056 | Interaction of the porcine reproductive and respiratory syndrome virus nucleocapsid protein with the inhibitor of MyoD family-a domain-containing protein |
Q39589026 | Interactions between equine cyclin T1, Tat, and TAR are disrupted by a leucine-to-valine substitution found in human cyclin T1. |
Q34987620 | Interactions between human cyclin T, Tat, and the transactivation response element (TAR) are disrupted by a cysteine to tyrosine substitution found in mouse cyclin T |
Q45316630 | Interactions of Tat with host cellular proteins |
Q79745144 | Interleukin-10 inhibits HIV-1 LTR-directed gene expression in human macrophages through the induction of cyclin T1 proteolysis |
Q28217472 | Interplay between cdk9 and NF-kappaB factors determines the level of HIV-1 gene transcription in astrocytic cells |
Q39921503 | Intragenic transcriptional cis-activation of the human immunodeficiency virus 1 does not result in allele-specific inhibition of the endogenous gene |
Q33853960 | Invisible RNA state dynamically couples distant motifs |
Q34171674 | Involvement of cyclin K posttranscriptional regulation in the formation of Artemia diapause cysts |
Q36143645 | Iron chelators ICL670 and 311 inhibit HIV-1 transcription |
Q36005484 | Isolation and characterization of mouse-human microcell hybrid cell clones permissive for infectious HIV particle release |
Q47844049 | Isolation and characterization of the human cyclin T1 promoter |
Q40852764 | Isolation of Cognate Cellular and Viral Ribonucleoprotein Complexes of HIV-1 RNA Applicable to Proteomic Discovery and Molecular Investigations. |
Q35131684 | Isolation, characterization, and genetic complementation of a cellular mutant resistant to retroviral infection |
Q28376959 | Isoquinolinesulphonamide derivatives inhibit transcriptional elongation of human immunodeficiency virus type 1 RNA in a promyelocytic model of latency |
Q89673835 | JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes |
Q33799971 | Jembrana disease virus Tat can regulate human immunodeficiency virus (HIV) long terminal repeat-directed gene expression and can substitute for HIV Tat in viral replication |
Q84654190 | Kick-sTARting HIV-1 transcription elongation by 7SK snRNP deporTATion |
Q24646322 | LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated |
Q25255905 | Latency: the hidden HIV-1 challenge |
Q47098902 | Latent HIV-1 TAR Regulates 7SK-responsive P-TEFb Target Genes and Targets Cellular Immune Responses in the Absence of Tat. |
Q36155046 | Latent HIV-1 infection occurs in multiple subsets of hematopoietic progenitor cells and is reversed by NF-κB activation. |
Q34452109 | Lentivirus and foamy virus vectors: novel gene therapy tools |
Q34754954 | Lentiviruses as gene transfer agents for delivery to non-dividing cells |
Q35012861 | Linking cyclins to transcriptional control. |
Q27651054 | Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex |
Q37010047 | Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation |
Q34075254 | Loop-loop interaction of HIV-1 TAR RNA with N3'-->P5' deoxyphosphoramidate aptamers inhibits in vitro Tat-mediated transcription |
Q39804456 | Loss of the Brm-type SWI/SNF chromatin remodeling complex is a strong barrier to the Tat-independent transcriptional elongation of human immunodeficiency virus type 1 transcripts |
Q38091888 | Lost in transcription: molecular mechanisms that control HIV latency |
Q37583411 | Lv1 inhibition of human immunodeficiency virus type 1 is counteracted by factors that stimulate synthesis or nuclear translocation of viral cDNA |
Q36699534 | Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR. |
Q24679741 | MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner |
Q36274198 | MD simulation of the Tat/Cyclin T1/CDK9 complex revealing the hidden catalytic cavity within the CDK9 molecule upon Tat binding |
Q35597624 | MYB elongation is regulated by the nucleic acid binding of NFκB p50 to the intronic stem-loop region. |
Q41927990 | Making Sense of Multifunctional Proteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription |
Q38212042 | Making a Short Story Long: Regulation of P-TEFb and HIV-1 Transcriptional Elongation in CD4+ T Lymphocytes and Macrophages. |
Q40118214 | Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR. |
Q37822089 | Mapping the architecture of the HIV-1 Tat circuit: A decision-making circuit that lacks bistability and exploits stochastic noise |
Q28140555 | Marek's disease herpesvirus transforming protein MEQ: a c-Jun analogue with an alternative life style |
Q34987465 | Matrix mediates the functional link between human immunodeficiency virus type 1 RNA nuclear export elements and the assembly competency of Gag in murine cells. |
Q40670620 | Matrix-induced inhibition of membrane binding contributes to human immunodeficiency virus type 1 particle assembly defects in murine cells. |
Q33680820 | Mechanism and regulation of transcriptional elongation by RNA polymerase II. |
Q41769072 | Mechanisms of HIV Transcriptional Regulation and Their Contribution to Latency |
Q33815611 | Mechanisms of HIV Transcriptional Regulation by Drugs of Abuse |
Q24558697 | Methylation of Tat by PRMT6 regulates human immunodeficiency virus type 1 gene expression |
Q34730602 | Mice transgenic for CD4-specific human CD4, CCR5 and cyclin T1 expression: a new model for investigating HIV-1 transmission and treatment efficacy |
Q21146658 | Mice transgenic for equine cyclin T1 and ELR1 are susceptible to equine infectious anemia virus infection |
Q61800035 | Modeling the Function of TATA Box Binding Protein in Transcriptional Changes Induced by HIV-1 Tat in Innate Immune Cells and the Effect of Methamphetamine Exposure |
Q24808657 | Modulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5 |
Q55405435 | Molecular Mechanisms of Injury in HIV-Associated Nephropathy. |
Q42836979 | Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication |
Q38310688 | Molecular beacon aptamer fluoresces in the presence of Tat protein of HIV-1. |
Q54441914 | Molecular dynamic simulations give insight into the mechanism of binding between 2-aminothiazole inhibitors and CDK5. |
Q40374329 | Molecular dynamics and MM/GBSA-integrated protocol probing the correlation between biological activities and binding free energies of HIV-1 TAR RNA inhibitors. |
Q28544421 | Molecular dynamics simulation and experimental verification of the interaction between cyclin T1 and HIV-1 Tat proteins |
Q36515063 | Molecular mechanisms of HIV latency |
Q33864438 | Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineage |
Q36278085 | Molecular mechanisms of HIV-1 proviral latency |
Q36916993 | Mouse T-cells restrict replication of human immunodeficiency virus at the level of integration |
Q33837992 | Mouse-human heterokaryons support efficient human immunodeficiency virus type 1 assembly |
Q33743566 | Multifaceted activities of the HIV-1 transactivator of transcription, Tat. |
Q47555946 | Multiple Inhibitory Factors Act in the Late Phase of HIV-1 Replication: a Systematic Review of the Literature |
Q34033118 | Multiple biological roles associated with the repeat (R) region of the HIV-1 RNA genome |
Q33603453 | Multiple blocks to human immunodeficiency virus type 1 replication in rodent cells |
Q35914370 | Multiple restrictions of human immunodeficiency virus type 1 in feline cells |
Q47822116 | Mutation of the major 5' splice site renders a CMV-driven HIV-1 proviral clone Tat-dependent: connections between transcription and splicing. |
Q39094752 | Mutations in the TAR hairpin affect the equilibrium between alternative conformations of the HIV-1 leader RNA |
Q35868299 | Mutual information analysis reveals coevolving residues in Tat that compensate for two distinct functions in HIV-1 gene expression |
Q42811398 | Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter |
Q30977476 | NKIAMRE, a novel conserved CDC2-related kinase with features of both mitogen-activated protein kinases and cyclin-dependent kinases |
Q30909558 | NMR characterization of a kissing complex formed between the TAR RNA element of HIV-1 and a DNA aptamer |
Q33602605 | Negative elongation factor is required for the maintenance of proviral latency but does not induce promoter-proximal pausing of RNA polymerase II on the HIV long terminal repeat |
Q39323907 | Negative elongation factor-mediated suppression of RNA polymerase II elongation of Kaposi's sarcoma-associated herpesvirus lytic gene expression |
Q35749130 | Neuropathologies in Transgenic Mice Expressing Human Immunodeficiency Virus Type 1 Tat Protein under the Regulation of the Astrocyte-Specific Glial Fibrillary Acidic Protein Promoter and Doxycycline |
Q21198772 | New insights into HIV-1-primary skin disorders |
Q34919381 | New insights into the control of HIV-1 transcription: when Tat meets the 7SK snRNP and super elongation complex (SEC). |
Q35122702 | New simian immunodeficiency virus infecting De Brazza's monkeys (Cercopithecus neglectus): evidence for a cercopithecus monkey virus clade |
Q42239136 | New, extended hairpin form of the TAR-2 RNA domain points to the structural polymorphism at the 5' end of the HIV-2 leader RNA. |
Q49455798 | Non-Coding RNAs As Transcriptional Regulators In Eukaryotes |
Q49236374 | Non-coding RNAs and retroviruses. |
Q35772862 | Noncoding RNA localisation mechanisms in chromatin regulation |
Q30885539 | Novel bovine lentiviral vectors based on Jembrana disease virus |
Q37547409 | Novel neuroprotective GSK-3β inhibitor restricts Tat-mediated HIV-1 replication |
Q35635000 | Nuclear import of the preintegration complex is blocked upon infection by human immunodeficiency virus type 1 in mouse cells |
Q28177130 | Nuclear protein phosphatase-1 regulates HIV-1 transcription |
Q34101377 | Nuclear receptor coactivator p160 proteins enhance the HIV-1 long terminal repeat promoter by bridging promoter-bound factors and the Tat-P-TEFb complex |
Q37866370 | Nuclear remodelling during viral infections |
Q25255186 | Oligomerization of HEXIM1 via 7SK snRNA and coiled-coil region directs the inhibition of P-TEFb |
Q33178132 | Oligonucleotide inhibition of the interaction of HIV-1 Tat protein with the trans-activation responsive region (TAR) of HIV RNA. |
Q39308951 | Opening of the TAR hairpin in the HIV-1 genome causes aberrant RNA dimerization and packaging |
Q39685303 | Optimized chimeras between kinase-inactive mutant Cdk9 and truncated cyclin T1 proteins efficiently inhibit Tat transactivation and human immunodeficiency virus gene expression |
Q39135199 | Overexpression of PRMT6 does not suppress HIV-1 Tat transactivation in cells naturally lacking PRMT6. |
Q89782162 | P-TEFb as A Promising Therapeutic Target |
Q26741360 | P-TEFb goes viral |
Q38896947 | P-TEFb goes viral. |
Q29620167 | P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II |
Q37356131 | P-TEFb- the final frontier |
Q40272529 | PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription |
Q36174095 | PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation. |
Q34650866 | Pathogenesis and treatment of HIV infection: the cellular, the immune system and the neuroendocrine systems perspective |
Q33649755 | Patterns of HIV-1 protein interaction identify perturbed host-cellular subsystems |
Q34343774 | Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 by targeting cellular, not viral, proteins |
Q46675052 | Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA. |
Q28487524 | Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes |
Q35805406 | Phosphorylation of HEXIM1 at Tyr271 and Tyr274 Promotes Release of P-TEFb from the 7SK snRNP Complex and Enhances Proviral HIV Gene Expression |
Q24806541 | Phosphorylation of HIV Tat by PKR increases interaction with TAR RNA and enhances transcription |
Q24537588 | Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation |
Q31072762 | Physical and functional interaction of HIV-1 Tat with E2F-4, a transcriptional regulator of mammalian cell cycle |
Q28143919 | Physical interaction between CDK9 and B-Myb results in suppression of B-Myb gene autoregulation |
Q28114798 | Physical interaction between pRb and cdk9/cyclinT2 complex |
Q34973763 | Polo-like kinase 1 inhibits the activity of positive transcription elongation factor of RNA Pol II b (P-TEFb). |
Q40501267 | Poly(ADP-ribose) polymerase-1 is a negative regulator of HIV-1 transcription through competitive binding to TAR RNA with Tat.positive transcription elongation factor b (p-TEFb) complex |
Q33708590 | Polyamide Amino Acids trimers as TAR RNA ligands and anti-HIV agents |
Q31807459 | Positive transcription elongation factor B phosphorylates hSPT5 and RNA polymerase II carboxyl-terminal domain independently of cyclin-dependent kinase-activating kinase. |
Q39682296 | Positive transcription elongation factor b (P-TEFb) contributes to dengue virus-stimulated induction of interleukin-8 (IL-8). |
Q35076669 | Postentry restriction of Mason-Pfizer monkey virus in mouse cells |
Q40073989 | Potent and selective inhibition of Tat-dependent HIV-1 replication in chronically infected cells by a novel naphthalene derivative JTK-101. |
Q30879123 | Potent inhibition of HIV-1 replication by a Tat mutant |
Q33814620 | Potent inhibition of human immunodeficiency virus type 1 (HIV-1) gene expression and virus production by an HIV-2 tat activation-response RNA decoy |
Q36821394 | Premature termination of transcription by RNAP II: the beginning of the end. |
Q35980829 | Primary T-cells from human CD4/CCR5-transgenic rats support all early steps of HIV-1 replication including integration, but display impaired viral gene expression |
Q73182068 | Principles and applications of a Tat-based assay for analyzing specific RNA-protein interactions in mammalian cells |
Q39704599 | Productive replication of Vif-chimeric HIV-1 in feline cells |
Q41815313 | Progranulin (granulin/epithelin precursor) and its constituent granulin repeats repress transcription from cellular promoters |
Q36370241 | Progress toward a human CD4/CCR5 transgenic rat model for de novo infection by human immunodeficiency virus type 1. |
Q35633540 | Pronounced acute immunosuppression in vivo mediated by HIV Tat challenge |
Q34654219 | Properties of RNA polymerase II elongation complexes before and after the P-TEFb-mediated transition into productive elongation. |
Q41683241 | Protein and RNA affinity selection techniques using HIV-1 Tat. |
Q37950254 | Protein intrinsic disorder as a flexible armor and a weapon of HIV-1. |
Q24318492 | Protein kinase C-delta regulates HIV-1 replication at an early post-entry step in macrophages |
Q38293944 | Proteomics in the investigation of HIV-1 interactions with host proteins |
Q40669160 | Quantification of the HIV transcriptional activator complex in live cells by image-based protein-protein interaction analysis |
Q40140632 | Quantitative analysis of RNA-mediated protein-protein interactions in living cells by FRET. |
Q41918740 | Quiescence promotes latent HIV infection and resistance to reactivation from latency with histone deacetylase inhibitors |
Q39550188 | R region sequences in the long terminal repeat of a murine retrovirus specifically increase expression of unspliced RNAs. |
Q29540749 | RNA Polymerase II C-Terminal Domain: Tethering Transcription to Transcript and Template |
Q39685491 | RNA interference directed against viral and cellular targets inhibits human immunodeficiency Virus Type 1 replication |
Q42027880 | RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation |
Q40069803 | Reactivation of HIV-1 from Latency by an Ingenol Derivative from Euphorbia Kansui. |
Q37305160 | Reactivation of latent HIV-1 in central memory CD4⁺ T cells through TLR-1/2 stimulation |
Q40108650 | Real-time visualization of chromatin modification in isolated nuclei. |
Q33633451 | Recent 5-year Findings and Technological Advances in the Proteomic Study of HIV-associated Disorders |
Q33958031 | Reciprocal modulatory interaction between human immunodeficiency virus type 1 Tat and transcription factor NFAT1. |
Q24515333 | Recognition of 5'-terminal TAR structure in human immunodeficiency virus-1 mRNA by eukaryotic translation initiation factor 2. |
Q33269333 | Recruitment and activation of RSK2 by HIV-1 Tat |
Q42181127 | Recruitment of TFIIH to the HIV LTR is a rate-limiting step in the emergence of HIV from latency |
Q40990135 | Recruitment of a protein complex containing Tat and cyclin T1 to TAR governs the species specificity of HIV-1 Tat. |
Q37191856 | Recruitment of cdk9 to the immediate-early viral transcriptosomes during human cytomegalovirus infection requires efficient binding to cyclin T1, a threshold level of IE2 86, and active transcription |
Q36405698 | Recruitment of cyclin T1/P-TEFb to an HIV type 1 long terminal repeat promoter proximal RNA target is both necessary and sufficient for full activation of transcription |
Q24675942 | Recruitment of human cyclin T1 to nuclear bodies through direct interaction with the PML protein |
Q37553804 | Regulation of CDK9 activity by phosphorylation and dephosphorylation. |
Q33769035 | Regulation of HIV-1 transcription |
Q33593821 | Regulation of SIV mac 239 basal long terminal repeat activity and viral replication in macrophages: functional roles of two CCAAT/enhancer-binding protein beta sites in activation and interferon beta-mediated suppression |
Q34685118 | Regulation of Tat acetylation and transactivation activity by the microtubule-associated deacetylase HDAC6. |
Q28289216 | Regulation of carboxyl-terminal domain phosphatase by HIV-1 tat protein |
Q35826285 | Regulation of cyclin T1 and HIV-1 Replication by microRNAs in resting CD4+ T lymphocytes. |
Q30350982 | Regulation of human immunodeficiency virus type 1 gene expression by clade-specific Tat proteins. |
Q40335491 | Regulation of polymerase II transcription by 7SK snRNA: two distinct RNA elements direct P-TEFb and HEXIM1 binding |
Q40236968 | Regulation of the Alternative Splicing and Function of Cyclin T1 by the Serine-Arginine-Rich Protein ASF/SF2. |
Q34816680 | Regulation of transcription elongation by phosphorylation |
Q36571363 | Relief of preintegration inhibition and characterization of additional blocks for HIV replication in primary mouse T cells. |
Q24552532 | Relief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter |
Q33940913 | Renal HIV expression is unaffected by serum LPS levels in an HIV transgenic mouse model of LPS induced kidney injury |
Q37099750 | Replication of equine infectious anemia virus in engineered mouse NIH 3T3 cells |
Q34467420 | Replication of human immunodeficiency viruses engineered with heterologous Tat-transactivation response element interactions |
Q34263935 | Repression of MHC determinants in HIV infection |
Q24315665 | Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter |
Q28141637 | Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription |
Q43416969 | Reservoirs for HIV-1. |
Q38610855 | Resveratrol, sirtuins, and viruses |
Q35836276 | Retroviral mRNA nuclear export elements regulate protein function and virion assembly. |
Q37183096 | Retroviral proteomics and interactomes: intricate balances of cell survival and viral replication |
Q37895742 | Retroviral restriction and dependency factors in primates and carnivores |
Q58700378 | Reversible Human Immunodeficiency Virus Type-1 Latency in Primary Human Monocyte-Derived Macrophages Induced by Sustained M1 Polarization |
Q39577905 | Ribosomal scanning on the 5'-untranslated region of the human immunodeficiency virus RNA genome |
Q27486874 | Ring Expanded Nucleoside Analogues Inhibit RNA Helicase and Intracellular Human Immunodeficiency Virus Type 1 Replication |
Q38430337 | Role of Host Factors on the Regulation of Tat-Mediated HIV-1 Transcription |
Q40945481 | Role of RNA polymerase II carboxy-terminal domain in coordinating transcription with RNA processing |
Q34033128 | Role of chromatin in HIV-1 transcriptional regulation |
Q37631411 | Role of noncoding RNAs in the regulation of P-TEFb availability and enzymatic activity |
Q26996314 | Roles and functions of HIV-1 Tat protein in the CNS: an overview |
Q28286819 | Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions |
Q24797263 | SIRT1 regulates HIV transcription via Tat deacetylation |
Q39855918 | SMAD proteins of oligodendroglial cells regulate transcription of JC virus early and late genes coordinately with the Tat protein of human immunodeficiency virus type 1. |
Q33990712 | SRp40 and SRp55 promote the translation of unspliced human immunodeficiency virus type 1 RNA |
Q37472861 | Sam68 functions in nuclear export and translation of HIV-1 RNA. |
Q30651338 | Screening RNA-binding libraries using Tat-fusion system in mammalian cells |
Q51868929 | Screening strategies to identify host factors associated with the early and late stages of HIV-1 life cycle. |
Q40439853 | Secreted complement regulatory protein clusterin interacts with dengue virus nonstructural protein 1. |
Q33196801 | Selection of TAR RNA-binding chameleon peptides by using a retroviral replication system |
Q37437860 | Selective control of gene expression by CDK9 in human cells |
Q59354479 | Semen exosomes promote transcriptional silencing of HIV-1 by disrupting NF-kB/Sp1/Tat circuitry |
Q24527316 | Sequence and transcriptional analyses of the fish retroviruses walleye epidermal hyperplasia virus types 1 and 2: evidence for a gene duplication. |
Q30870026 | Sequence of goat cyclin T1 cDNA, gene organisation and expression analysis |
Q34656952 | Short chain fatty acids potently induce latent HIV-1 in T-cells by activating P-TEFb and multiple histone modifications |
Q34293568 | Small molecule modulators of cyclin-dependent kinases for cancer therapy |
Q33824990 | Species-specific, postentry barriers to primate immunodeficiency virus infection |
Q93010915 | Specific Activation In Vivo of HIV-1 by a Bromodomain Inhibitor from Monocytic Cells in Humanized Mice under Antiretroviral Therapy |
Q36675349 | Specific Reactivation of Latent HIV-1 by dCas9-SunTag-VP64-mediated Guide RNA Targeting the HIV-1 Promoter |
Q35059684 | Specific interaction of Tat with the human but not rodent P-TEFb complex mediates the species-specific Tat activation of HIV-1 transcription |
Q39016210 | Specific reactivation of latent HIV-1 with designer zinc-finger transcription factors targeting the HIV-1 5'-LTR promoter |
Q24537527 | Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequences |
Q35761279 | Squamous epithelial proliferation induced by walleye dermal sarcoma retrovirus cyclin in transgenic mice |
Q37352913 | Stable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals |
Q37137908 | Stem-loop binding protein is a multifaceted cellular regulator of HIV-1 replication |
Q42468627 | Stimulation of Tat-associated kinase-independent transcriptional elongation from the human immunodeficiency virus type-1 long terminal repeat by a cellular enhancer |
Q35107931 | Stimulation of Tat-independent transcriptional processivity from the HIV-1 LTR promoter by matrix attachment regions |
Q28214807 | Stimulatory effect of splicing factors on transcriptional elongation |
Q33835795 | Strict control of human immunodeficiency virus type 1 replication by a genetic switch: Tet for Tat. |
Q27638717 | Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain |
Q24632055 | Structural determinants and mechanism of HIV-1 genome packaging |
Q27652984 | Structural insights into the cyclin T1-Tat-TAR RNA transcription activation complex from EIAV |
Q58762403 | Structural insights into the functional diversity of the CDK-cyclin family |
Q90258885 | Structural mechanism for HIV-1 TAR loop recognition by Tat and the super elongation complex |
Q27622070 | Structural rearrangements of HIV-1 Tat-responsive RNA upon binding of neomycin B |
Q77914240 | Structure and function of HIV-1 and SIV Tat proteins based on carboxy-terminal truncations, chimeric Tat constructs, and NMR modeling |
Q22009021 | Structure and function of the human transcription elongation factor DSIF |
Q59070952 | Structure of activated transcription complex Pol II–DSIF–PAF–SPT6 |
Q96431678 | Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation |
Q59087446 | Structure of paused transcription complex Pol II-DSIF-NELF |
Q34449437 | Structure-based design of a dimeric RNA-peptide complex |
Q40275061 | Super elongation complex promotes early HIV transcription and its function is modulated by P-TEFb |
Q37101393 | Suppression of HIV-1 Nef translation by Sam68 mutant-induced stress granules and nef mRNA sequestration |
Q38356107 | Suppression of an intrinsic strand transfer activity of HIV-1 Tat protein by its second-exon sequences |
Q39545943 | Surface plasmon resonance kinetic studies of the HIV TAR RNA kissing hairpin complex and its stabilization by 2-thiouridine modification |
Q34976301 | Susceptibility of Mink ( Mustera vision )-Derived Cells to Replication by Human Immunodeficiency Virus Type 1 |
Q39606789 | Susceptibility of rat-derived cells to replication by human immunodeficiency virus type 1. |
Q39852737 | Synergistic effect of human CycT1 and CRM1 on HIV-1 propagation in rat T cells and macrophages |
Q34796643 | Systematic Analysis of the Functions of Lysine Acetylation in the Regulation of Tat Activity |
Q35091855 | Systematic approaches towards the development of host-directed antiviral therapeutics |
Q35613792 | T-cell and neuronal apoptosis in HIV infection: implications for therapeutic intervention |
Q35113716 | T-cell receptor signaling enhances transcriptional elongation from latent HIV proviruses by activating P-TEFb through an ERK-dependent pathway |
Q34030432 | TAR RNA loop: a scaffold for the assembly of a regulatory switch in HIV replication |
Q41852627 | TAR-RNA recognition by a novel cyclic aminoglycoside analogue. |
Q28188877 | TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription |
Q24600874 | TIP30 has an intrinsic kinase activity required for up-regulation of a subset of apoptotic genes |
Q24304062 | TRIM5α and Species Tropism of HIV/SIV |
Q39724730 | Targeting of CDK8 to a promoter-proximal RNA element demonstrates catalysis-dependent activation of gene expression. |
Q40079572 | Targeting of CDK9 with indirubin 3'-monoxime safely and durably reduces HIV viremia in chronically infected humanized mice |
Q35910232 | Targeting of mTOR catalytic site inhibits multiple steps of the HIV-1 lifecycle and suppresses HIV-1 viremia in humanized mice |
Q54210140 | Targeting the Latent Reservoir for HIV-1. |
Q28214887 | Tat acetyl-acceptor lysines are important for human immunodeficiency virus type-1 replication |
Q33957746 | Tat activates human immunodeficiency virus type 1 transcriptional elongation independent of TFIIH kinase |
Q34161703 | Tat and trans-activation-responsive (TAR) RNA-independent induction of HIV-1 long terminal repeat by human and murine cyclin T1 requires Sp1. |
Q34033142 | Tat as a transcriptional activator and a potential therapeutic target for HIV-1. |
Q35993736 | Tat as one key to HIV-induced immune pathogenesis and Tat (correction of Pat) toxoid as an important component of a vaccine |
Q28144181 | Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection |
Q54254325 | Tat controls transcriptional persistence of unintegrated HIV genome in primary human macrophages. |
Q90292108 | Tat expression led to increased histone 3 tri-methylation at lysine 27 and contributed to HIV latency in astrocytes through regulation of MeCP2 and Ezh2 expression |
Q28116305 | Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription |
Q34156984 | Tat stimulates cotranscriptional capping of HIV mRNA. |
Q78873851 | Tat's seductive side |
Q33455685 | Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAs |
Q22003803 | Tat-SF1 protein associates with RAP30 and human SPT5 proteins |
Q28138220 | Tat-associated kinase (P-TEFb): a component of transcription preinitiation and elongation complexes |
Q33786066 | Tat-associated kinase, TAK, activity is regulated by distinct mechanisms in peripheral blood lymphocytes and promonocytic cell lines |
Q45316601 | Tat-mediated elongation of the HIV-1 transcript |
Q44720095 | Techniques to analyze the HIV-1 Tat and TAR RNA-dependent recruitment and activation of the cyclin T1: CDK9 (P-TEFb) transcription elongation factor. |
Q41510614 | The 5' UTR of HIV-1 full-length mRNA and the Tat viral protein modulate the programmed -1 ribosomal frameshift that generates HIV-1 enzymes |
Q28206012 | The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription |
Q27676733 | The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat |
Q41862317 | The Brome mosaic virus subgenomic promoter hairpin is structurally similar to the iron-responsive element and functionally equivalent to the minus-strand core promoter stem-loop C. |
Q39777846 | The Cellular lysine methyltransferase Set7/9-KMT7 binds HIV-1 TAR RNA, monomethylates the viral transactivator Tat, and enhances HIV transcription. |
Q40731101 | The HIV-1 Tat Protein Is Monomethylated at Lysine 71 by the Lysine Methyltransferase KMT7 |
Q24596637 | The HIV-1 Tat cellular coactivator Tat-SF1 is a general transcription elongation factor |
Q38286131 | The HIV-1 Tat protein has a versatile role in activating viral transcription |
Q54977707 | The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation. |
Q40135003 | The HIV-1 Tat protein: mechanism of action and target for HIV-1 cure strategies. |
Q36578522 | The HIV-1 transgenic rat model of neuroHIV. |
Q33893725 | The Human Immunodeficiency Virus 1 ASP RNA promotes viral latency by recruiting the Polycomb Repressor Complex 2 and promoting nucleosome assembly |
Q34382921 | The MHC class II transactivator: prey and hunter in infectious diseases |
Q38043907 | The Mediator complex and transcription elongation |
Q37027897 | The N-end rule and retroviral infection: no effect on integrase |
Q91661378 | The Per-1 Short Isoform Inhibits de novo HIV-1 Transcription in Resting CD4+ T-cells |
Q34654513 | The RING finger ubiquitin ligase RNF125/TRAC-1 down-modulates HIV-1 replication in primary human peripheral blood mononuclear cells |
Q42117931 | The Role of RNA Polymerase II Elongation Control in HIV-1 Gene Expression, Replication, and Latency |
Q47824549 | The Sp1 transcription factor does not directly interact with the HIV-1 Tat protein. |
Q42431758 | The TAR hairpin of human immunodeficiency virus type 1 can be deleted when not required for Tat-mediated activation of transcription |
Q35829282 | The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency |
Q35973578 | The Vaginal Acquisition and Dissemination of HIV-1 Infection in a Novel Transgenic Mouse Model Is Facilitated by Coinfection with Herpes Simplex Virus 2 and Is Inhibited by Microbicide Treatment. |
Q42508685 | The Werner syndrome helicase is a cofactor for HIV-1 long terminal repeat transactivation and retroviral replication |
Q35072999 | The Yin and Yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation |
Q39580108 | The ability of positive transcription elongation factor B to transactivate human immunodeficiency virus transcription depends on a functional kinase domain, cyclin T1, and Tat. |
Q28189849 | The apical loop of the HIV-1 TAR RNA hairpin is stabilized by a cross-loop base pair |
Q28254964 | The breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1 |
Q24316236 | The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription |
Q35188989 | The carboxyl terminus of phage HK022 Nun includes a novel zinc-binding motif and a tryptophan required for transcription termination. |
Q37958430 | The control of HIV transcription: keeping RNA polymerase II on track |
Q36906001 | The effects of cocaine on HIV transcription |
Q39005055 | The emerging picture of CDK9/P-TEFb: more than 20 years of advances since PITALRE. |
Q24298498 | The functional role of an interleukin 6-inducible CDK9.STAT3 complex in human gamma-fibrinogen gene expression |
Q24554329 | The growth factor granulin interacts with cyclin T1 and modulates P-TEFb-dependent transcription |
Q28198162 | The histone acetyltransferase, hGCN5, interacts with and acetylates the HIV transactivator, Tat |
Q24307870 | The histone chaperone protein Nucleosome Assembly Protein-1 (hNAP-1) binds HIV-1 Tat and promotes viral transcription |
Q24318776 | The human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcription |
Q33805882 | The human immunodeficiency virus type 1 TAR RNA upper stem-loop plays distinct roles in reverse transcription and RNA packaging |
Q35211232 | The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein |
Q34362436 | The leader of the HIV-1 RNA genome forms a compactly folded tertiary structure |
Q21136168 | The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK |
Q34544409 | The molecular biology of HIV latency: breaking and restoring the Tat-dependent transcriptional circuit |
Q28143137 | The nuclear receptor chicken ovalbumin upstream promoter transcription factor interacts with HIV-1 Tat and stimulates viral replication in human microglial cells |
Q28595060 | The positive transcription elongation factor b is an essential cofactor for the activation of transcription by myocyte enhancer factor 2 |
Q28251761 | The regulation of HIV-1 transcription: molecular targets for chemotherapeutic intervention |
Q39580918 | The secondary structure of the R region of a murine leukemia virus is important for stimulation of long terminal repeat-driven gene expression. |
Q24323313 | The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation |
Q36119592 | The transcriptional cycle of HIV-1 in real-time and live cells. |
Q40951736 | The transcriptional inhibitors, actinomycin D and alpha-amanitin, activate the HIV-1 promoter and favor phosphorylation of the RNA polymerase II C-terminal domain |
Q33700143 | The transcriptional transactivator Tat selectively regulates viral splicing. |
Q30413065 | The use of Nanotrap particles technology in capturing HIV-1 virions and viral proteins from infected cells |
Q33957637 | The yeast C-type cyclin Ctk2p is phosphorylated and rapidly degraded by the ubiquitin-proteasome pathway |
Q34133579 | Therapeutic targeting of human immunodeficiency virus type-1 latency: current clinical realities and future scientific possibilities |
Q28208318 | Three RNA polymerase II carboxyl-terminal domain kinases display distinct substrate preferences |
Q37428613 | Tip110 protein binds to unphosphorylated RNA polymerase II and promotes its phosphorylation and HIV-1 long terminal repeat transcription |
Q44018972 | Topoisomerase I and ATP activate cDNA synthesis of human immunodeficiency virus type 1. |
Q37194356 | Transcription elongation control by the 7SK snRNP complex: Releasing the pause. |
Q24533266 | Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages |
Q39069527 | Transcription elongation regulator 1 (TCERG1) regulates competent RNA polymerase II-mediated elongation of HIV-1 transcription and facilitates efficient viral replication. |
Q41853689 | Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation. |
Q36857070 | Transcription of HIV: Tat and cellular chromatin |
Q40856625 | Transcriptional activity of positive transcription elongation factor b kinase in vivo requires the C-terminal domain of RNA polymerase II. |
Q34030804 | Transcriptional and posttranscriptional regulation of HIV-1 gene expression |
Q24554483 | Transcriptional cofactor CA150 regulates RNA polymerase II elongation in a TATA-box-dependent manner |
Q33591923 | Transcriptional control by cell-cycle regulators: a review |
Q26999858 | Transcriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cure |
Q28275557 | Transcriptional control: Tat cofactors and transcriptional elongation |
Q34443670 | Transcriptional interference antagonizes proviral gene expression to promote HIV latency |
Q44786579 | Transcriptional pausing at +62 of the HIV-1 nascent RNA modulates formation of the TAR RNA structure |
Q35155025 | Transcriptional profiles of latent human immunodeficiency virus in infected individuals: effects of Tat on the host and reservoir |
Q40932318 | Transcriptional regulation by targeted recruitment of cyclin-dependent CDK9 kinase in vivo |
Q34620906 | Transcriptional regulation of HIV-1 gene expression by p53. |
Q35186960 | Transcriptional repression by the Caenorhabditis elegans germ-line protein PIE-1. |
Q24534907 | Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain |
Q37690181 | Transfection of nerve cells. |
Q37398621 | Transgenic expression of the human LEDGF/p75 gene relieves the species barrier against HIV-1 infection in mouse cells |
Q39685314 | Transient induction of cyclin T1 during human macrophage differentiation regulates human immunodeficiency virus type 1 Tat transactivation function. |
Q39272683 | Transition step during assembly of HIV Tat:P-TEFb transcription complexes and transfer to TAR RNA. |
Q34381967 | Triptolide inhibits human immunodeficiency virus type 1 replication by promoting proteasomal degradation of Tat protein |
Q40190265 | Two G-rich regulatory elements located adjacent to and 440 nucleotides downstream of the core poly(A) site of the intronless melanocortin receptor 1 gene are critical for efficient 3' end processing |
Q34363290 | Two alternating structures of the HIV-1 leader RNA |
Q77716325 | Ubiquitous expression of goat cyclin T1 in transgenic mice |
Q33930482 | Ubiquitylation of Cdk9 by Skp2 facilitates optimal Tat transactivation |
Q47695033 | Unexpected high testis-specific transcriptional activity of the cyclin T1 promoter in transgenic mice |
Q36202709 | Use of ATP analogs to inhibit HIV-1 transcription |
Q45416488 | Vaccination of mice with replication-defective human immunodeficiency virus induces cellular and humoral immunity and protects against vaccinia virus-gag challenge |
Q83393426 | Viral RNAs: lessons from the enemy |
Q33920746 | Viral cyclins |
Q34104253 | Viral replication and the coactivators p300 and CBP. |
Q35026881 | Viral-host interactions that control HIV-1 transcriptional elongation |
Q24813634 | Virus-host interactions: new insights from the small RNA world. |
Q40786197 | Visualization of in vivo direct interaction between HIV-1 TAT and human cyclin T1 in specific subcellular compartments by fluorescence resonance energy transfer |
Q35121356 | Visualization of positive transcription elongation factor b (P-TEFb) activation in living cells |
Q33785258 | Walleye retroviruses associated with skin tumors and hyperplasias encode cyclin D homologs. |
Q33400343 | Yeast genetic analysis reveals the involvement of chromatin reassembly factors in repressing HIV-1 basal transcription |
Q35034218 | ZASC1 stimulates HIV-1 transcription elongation by recruiting P-TEFb and TAT to the LTR promoter |
Q55360108 | Zinc-Finger Nucleases Induced by HIV-1 Tat Excise HIV-1 from the Host Genome in Infected and Latently Infected Cells. |
Q38295485 | c-Myc mediates activation of the cad promoter via a post-RNA polymerase II recruitment mechanism |
Q28204153 | c-Myc recruits P-TEFb for transcription, cellular proliferation and apoptosis |
Q24629119 | c-Myc regulates transcriptional pause release |
Q30479670 | iRED analysis of TAR RNA reveals motional coupling, long-range correlations, and a dynamical hinge |
Q35641069 | p53-derived host restriction of HIV-1 replication by protein kinase R-mediated Tat phosphorylation and inactivation |
Q33292132 | p73 Interacts with human immunodeficiency virus type 1 Tat in astrocytic cells and prevents its acetylation on lysine 28. |
Q36827396 | tat Exon 1 exhibits functional diversity during HIV-1 subtype C primary infection. |
Search more.