scholarly article | Q13442814 |
P2093 | author name string | Alan D Frankel | |
John D Gross | |||
Tyler B Faust | |||
Jennifer M Binning | |||
P2860 | cites work | HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation | Q21089617 |
Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps | Q21131559 | ||
Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2 | Q21559418 | ||
THE HIV-1 REV PROTEIN | Q22241975 | ||
HIV-1 Nef impairs MHC class II antigen presentation and surface expression | Q22248080 | ||
Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein | Q22251058 | ||
Direct evidence of extensive diversity of HIV-1 in Kinshasa by 1960 | Q22251093 | ||
Serine phosphorylation-independent downregulation of cell-surface CD4 by nef | Q22251290 | ||
T-cell differentiation factor CBF-β regulates HIV-1 Vif-mediated evasion of host restriction | Q24300389 | ||
Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways | Q24302300 | ||
Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing | Q24318920 | ||
SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef | Q24338889 | ||
HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation | Q24338895 | ||
Structure--function relationships in HIV-1 Nef. | Q24522550 | ||
Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor | Q24563382 | ||
HIV transcriptional activation by the accessory protein, VPR, is mediated by the p300 co-activator | Q24569559 | ||
HIV Rev response element (RRE) directs assembly of the Rev homooligomer into discrete asymmetric complexes | Q24606750 | ||
c-Myc regulates transcriptional pause release | Q24629119 | ||
Crystal structure of HIV-1 Tat complexed with human P-TEFb | Q24634569 | ||
Vpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/Tetherin via a {beta}TrCP-dependent mechanism | Q24644811 | ||
HIV-1 accessory protein Vpu internalizes cell-surface BST-2/tetherin through transmembrane interactions leading to lysosomes | Q24646984 | ||
HIV-1 Rev protein assembles on viral RNA one molecule at a time | Q24658214 | ||
The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent expression of antiapoptotic factors | Q24670601 | ||
The Vpu protein of human immunodeficiency virus type 1 forms cation-selective ion channels | Q24680307 | ||
Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle | Q24680705 | ||
HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1 | Q24681112 | ||
Tat protein induces self-perpetuating permissivity for productive HIV-1 infection | Q24683211 | ||
NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation | Q42128724 | ||
Structural basis for hijacking CBF-β and CUL5 E3 ligase complex by HIV-1 Vif. | Q42152378 | ||
HIV type 1 viral infectivity factor and the RUNX transcription factors interact with core binding factor β on genetically distinct surfaces. | Q42348425 | ||
Human immunodeficiency virus type 1 vpr protein transactivation function: mechanism and identification of domains involved | Q42464739 | ||
A novel gene of HIV-1, vpu, and its 16-kilodalton product | Q42656133 | ||
CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression. | Q43239447 | ||
Transcriptional regulation and function during the human cell cycle | Q43515454 | ||
Identification of an ion channel activity of the Vpu transmembrane domain and its involvement in the regulation of virus release from HIV-1-infected cells | Q45765997 | ||
Tat trans-activates the human immunodeficiency virus through a nascent RNA target | Q45847022 | ||
A new HTLV-III/LAV encoded antigen detected by antibodies from AIDS patients | Q46065811 | ||
HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product | Q59048755 | ||
[The Nef protein of HIV-1 associates with rafts and primes T cells for activation] | Q73461830 | ||
The human immunodeficiency virus (HIV) type 2 envelope protein is a functional complement to HIV type 1 Vpu that enhances particle release of heterologous retroviruses. | Q35873115 | ||
The kappaB sites in the human immunodeficiency virus type 1 long terminal repeat enhance virus replication yet are not absolutely required for viral growth | Q35888601 | ||
Endocytosis and targeting of exogenous HIV-1 Tat protein | Q35926764 | ||
NF-κB, the first quarter-century: remarkable progress and outstanding questions | Q26822516 | ||
Formation of mobile chromatin-associated nuclear foci containing HIV-1 Vpr and VPRBP is critical for the induction of G2 cell cycle arrest | Q27313676 | ||
Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta | Q27630690 | ||
The Marburg virus VP24 protein interacts with Keap1 to activate the cytoprotective antioxidant response pathway | Q27682227 | ||
AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter | Q27683845 | ||
The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction | Q27727807 | ||
Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7 | Q27748910 | ||
CRM1 is an export receptor for leucine-rich nuclear export signals | Q27860453 | ||
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein | Q27860488 | ||
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes | Q28116607 | ||
Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection | Q28144181 | ||
DNA deamination mediates innate immunity to retroviral infection | Q28179534 | ||
Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators | Q28203103 | ||
HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages | Q28204428 | ||
The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription | Q28206012 | ||
Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex | Q28210666 | ||
Controlling the elongation phase of transcription with P-TEFb | Q28255518 | ||
A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA | Q28263974 | ||
Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4 | Q28267929 | ||
A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif | Q28276184 | ||
The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA | Q28279502 | ||
Retroviral restriction by APOBEC proteins | Q28290721 | ||
Interaction of Virion Protein Vpr of Human Immunodeficiency Virus Type 1 with Cellular Transcription Factor Sp1 and trans-Activation of Viral Long Terminal Repeat | Q28291807 | ||
The role of Vpr in HIV-1 pathogenesis | Q28301540 | ||
Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection | Q28304773 | ||
A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73 | Q28305429 | ||
Dimerization with PEBP2beta protects RUNX1/AML1 from ubiquitin-proteasome-mediated degradation | Q28348865 | ||
Activation of HIV-1 from latent infection via synergy of RUNX1 inhibitor Ro5-3335 and SAHA | Q28541244 | ||
Bst-2/HM1.24 is a raft-associated apical membrane protein with an unusual topology | Q28580409 | ||
The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA | Q28652351 | ||
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53 | Q29547773 | ||
Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu | Q29547836 | ||
The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif | Q29618938 | ||
HIV-1 accessory proteins--ensuring viral survival in a hostile environment | Q29619538 | ||
HIV Vpu Interferes with NF-κB Activity but Not with Interferon Regulatory Factor 3. | Q36080904 | ||
Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity | Q36185332 | ||
Functional Segregation of Overlapping Genes in HIV. | Q36226848 | ||
Transcriptional regulation of APOBEC3 antiviral immunity through the CBF-β/RUNX axis | Q36276957 | ||
HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail | Q36322591 | ||
The human immunodeficiency virus type 1 (HIV-1) Vpu protein interferes with an early step in the biosynthesis of major histocompatibility complex (MHC) class I molecules | Q36377062 | ||
Life and death decisions by the E2F transcription factors | Q36499727 | ||
HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells | Q36520900 | ||
Retinoblastoma family proteins as key targets of the small DNA virus oncoproteins. | Q36579274 | ||
The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation | Q36668708 | ||
Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4 | Q36687143 | ||
Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein | Q37104090 | ||
Activation of the DNA Damage Response Is a Conserved Function of HIV-1 and HIV-2 Vpr That Is Independent of SLX4 Recruitment | Q37253817 | ||
Analysis of human immunodeficiency virus type 1 transcriptional elongation in resting CD4+ T cells in vivo | Q37348552 | ||
Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variants | Q37377094 | ||
AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation | Q37475277 | ||
The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongation | Q37506941 | ||
Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation. | Q37574658 | ||
CBFβ enhances de novo protein biosynthesis of its binding partners HIV-1 Vif and RUNX1 and potentiates the Vif-induced degradation of APOBEC3G. | Q37714020 | ||
Mechanisms underlying HIV-1 Vpu-mediated viral egress | Q38211428 | ||
Stimulation of NF-κB activity by the HIV restriction factor BST2. | Q39230459 | ||
Innate sensing of HIV-1 assembly by Tetherin induces NFκB-dependent proinflammatory responses. | Q39243642 | ||
Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo. | Q39270892 | ||
Anti-tetherin activities in Vpu-expressing primate lentiviruses | Q39391944 | ||
Contribution of Vpu, Env, and Nef to CD4 down-modulation and resistance of human immunodeficiency virus type 1-infected T cells to superinfection | Q39593653 | ||
Cell cycle- and Vpr-mediated regulation of human immunodeficiency virus type 1 expression in primary and transformed T-cell lines | Q39594512 | ||
HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment | Q39696123 | ||
HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP | Q39703646 | ||
Antagonism to and intracellular sequestration of human tetherin by the human immunodeficiency virus type 2 envelope glycoprotein | Q39801517 | ||
HIV-1 antagonism of CD317 is species specific and involves Vpu-mediated proteasomal degradation of the restriction factor | Q39872885 | ||
Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR. | Q40118214 | ||
Phosphatidylinositol-(4,5)-bisphosphate enables efficient secretion of HIV-1 Tat by infected T-cells | Q40508633 | ||
Vpr-mediated incorporation of UNG2 into HIV-1 particles is required to modulate the virus mutation rate and for replication in macrophages | Q40564751 | ||
HIV-1 Vpu sequesters beta-transducin repeat-containing protein (betaTrCP) in the cytoplasm and provokes the accumulation of beta-catenin and other SCFbetaTrCP substrates. | Q40625711 | ||
Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R. | Q40649004 | ||
The human immunodeficiency virus type 1 Vpu protein inhibits NF-kappa B activation by interfering with beta TrCP-mediated degradation of Ikappa B. | Q40816820 | ||
Cooperative interaction between HIV-1 regulatory proteins Tat and Vpr modulates transcription of the viral genome | Q40863490 | ||
HIV-1 Vpr increases viral expression by manipulation of the cell cycle: a mechanism for selection of Vpr in vivo | Q41071784 | ||
HIV-1 Rev downregulates Tat expression and viral replication via modulation of NAD(P)H:quinine oxidoreductase 1 (NQO1). | Q41172672 | ||
Vif proteins of human and simian immunodeficiency viruses require cellular CBFβ to degrade APOBEC3 restriction factors | Q41878273 | ||
RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation | Q42027880 | ||
The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein | Q29619540 | ||
Cellular uptake of the tat protein from human immunodeficiency virus | Q29620627 | ||
Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains. | Q30382590 | ||
Activation of the ATR pathway by human immunodeficiency virus type 1 Vpr involves its direct binding to chromatin in vivo | Q33227756 | ||
DDB1 maintains genome integrity through regulation of Cdt1 | Q33255742 | ||
HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase | Q33290831 | ||
HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells | Q33363091 | ||
Human immunodeficiency virus type 1 has an additional coding sequence in the central region of the genome | Q33649232 | ||
Leveraging APOBEC3 proteins to alter the HIV mutation rate and combat AIDS. | Q33654949 | ||
Association of Tat with Promoters of PTEN and PP2A Subunits Is Key to Transcriptional Activation of Apoptotic Pathways in HIV-Infected CD4+ T Cells | Q33700607 | ||
Functional domains within the human immunodeficiency virus type 2 envelope protein required to enhance virus production | Q33737672 | ||
Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complex | Q33835387 | ||
HIV-1 Nef induces proinflammatory state in macrophages through its acidic cluster domain: involvement of TNF alpha receptor associated factor 2. | Q34008771 | ||
Tetherin inhibits HIV-1 release by directly tethering virions to cells | Q34019962 | ||
Lentiviral Vif degrades the APOBEC3Z3/APOBEC3H protein of its mammalian host and is capable of cross-species activity | Q34045987 | ||
RNA-guided assembly of Rev-RRE nuclear export complexes | Q34080345 | ||
Identification of a protein encoded by the vpu gene of HIV-1. | Q34163678 | ||
Feedback regulation of human immunodeficiency virus type 1 expression by the Rev protein | Q34220747 | ||
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection | Q34242229 | ||
Functional role of human immunodeficiency virus type 1 vpu. | Q34288200 | ||
Structural insights for HIV-1 therapeutic strategies targeting Vif. | Q34433647 | ||
Nef proteins from simian immunodeficiency viruses are tetherin antagonists. | Q34658653 | ||
HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription | Q34896128 | ||
RNA-directed remodeling of the HIV-1 protein Rev orchestrates assembly of the Rev-Rev response element complex | Q35179371 | ||
The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein | Q35211232 | ||
HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages. | Q35234824 | ||
Differential regulation of NF-κB-mediated proviral and antiviral host gene expression by primate lentiviral Nef and Vpu proteins | Q35549043 | ||
Transmembrane domain determinants of CD4 Downregulation by HIV-1 Vpu. | Q35665886 | ||
Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor. | Q35785393 | ||
The viral infectivity factor (Vif) of HIV-1 unveiled | Q35791995 | ||
Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription. | Q35804608 | ||
HIV Rev Assembly on the Rev Response Element (RRE): A Structural Perspective | Q35808679 | ||
The p6gag domain of human immunodeficiency virus type 1 is sufficient for the incorporation of Vpr into heterologous viral particles | Q35838540 | ||
Vpr-induced cell cycle arrest is conserved among primate lentiviruses. | Q35859146 | ||
P433 | issue | 1 | |
P304 | page(s) | 241-260 | |
P577 | publication date | 2017-09-01 | |
P1433 | published in | Annual Review of Virology | Q19962702 |
P1476 | title | Making Sense of Multifunctional Proteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription | |
P478 | volume | 4 |