| P2093 | author name string | Alan D Frankel | |
| | John D Gross | |
| | Tyler B Faust | |
| | Jennifer M Binning | |
| P2860 | cites work | HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation | Q21089617 |
| | Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps | Q21131559 |
| | Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2 | Q21559418 |
| | THE HIV-1 REV PROTEIN | Q22241975 |
| | HIV-1 Nef impairs MHC class II antigen presentation and surface expression | Q22248080 |
| | Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein | Q22251058 |
| | Direct evidence of extensive diversity of HIV-1 in Kinshasa by 1960 | Q22251093 |
| | Serine phosphorylation-independent downregulation of cell-surface CD4 by nef | Q22251290 |
| | T-cell differentiation factor CBF-β regulates HIV-1 Vif-mediated evasion of host restriction | Q24300389 |
| | Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways | Q24302300 |
| | Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing | Q24318920 |
| | SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef | Q24338889 |
| | HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation | Q24338895 |
| | Structure--function relationships in HIV-1 Nef. | Q24522550 |
| | Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor | Q24563382 |
| | HIV transcriptional activation by the accessory protein, VPR, is mediated by the p300 co-activator | Q24569559 |
| | HIV Rev response element (RRE) directs assembly of the Rev homooligomer into discrete asymmetric complexes | Q24606750 |
| | c-Myc regulates transcriptional pause release | Q24629119 |
| | Crystal structure of HIV-1 Tat complexed with human P-TEFb | Q24634569 |
| | Vpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/Tetherin via a {beta}TrCP-dependent mechanism | Q24644811 |
| | HIV-1 accessory protein Vpu internalizes cell-surface BST-2/tetherin through transmembrane interactions leading to lysosomes | Q24646984 |
| | HIV-1 Rev protein assembles on viral RNA one molecule at a time | Q24658214 |
| | The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent expression of antiapoptotic factors | Q24670601 |
| | The Vpu protein of human immunodeficiency virus type 1 forms cation-selective ion channels | Q24680307 |
| | Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle | Q24680705 |
| | HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1 | Q24681112 |
| | Tat protein induces self-perpetuating permissivity for productive HIV-1 infection | Q24683211 |
| | NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation | Q42128724 |
| | Structural basis for hijacking CBF-β and CUL5 E3 ligase complex by HIV-1 Vif. | Q42152378 |
| | HIV type 1 viral infectivity factor and the RUNX transcription factors interact with core binding factor β on genetically distinct surfaces. | Q42348425 |
| | Human immunodeficiency virus type 1 vpr protein transactivation function: mechanism and identification of domains involved | Q42464739 |
| | A novel gene of HIV-1, vpu, and its 16-kilodalton product | Q42656133 |
| | CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression. | Q43239447 |
| | Transcriptional regulation and function during the human cell cycle | Q43515454 |
| | Identification of an ion channel activity of the Vpu transmembrane domain and its involvement in the regulation of virus release from HIV-1-infected cells | Q45765997 |
| | Tat trans-activates the human immunodeficiency virus through a nascent RNA target | Q45847022 |
| | A new HTLV-III/LAV encoded antigen detected by antibodies from AIDS patients | Q46065811 |
| | HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product | Q59048755 |
| | [The Nef protein of HIV-1 associates with rafts and primes T cells for activation] | Q73461830 |
| | The human immunodeficiency virus (HIV) type 2 envelope protein is a functional complement to HIV type 1 Vpu that enhances particle release of heterologous retroviruses. | Q35873115 |
| | The kappaB sites in the human immunodeficiency virus type 1 long terminal repeat enhance virus replication yet are not absolutely required for viral growth | Q35888601 |
| | Endocytosis and targeting of exogenous HIV-1 Tat protein | Q35926764 |
| | NF-κB, the first quarter-century: remarkable progress and outstanding questions | Q26822516 |
| | Formation of mobile chromatin-associated nuclear foci containing HIV-1 Vpr and VPRBP is critical for the induction of G2 cell cycle arrest | Q27313676 |
| | Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta | Q27630690 |
| | The Marburg virus VP24 protein interacts with Keap1 to activate the cytoprotective antioxidant response pathway | Q27682227 |
| | AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter | Q27683845 |
| | The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction | Q27727807 |
| | Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7 | Q27748910 |
| | CRM1 is an export receptor for leucine-rich nuclear export signals | Q27860453 |
| | Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein | Q27860488 |
| | 7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes | Q28116607 |
| | Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection | Q28144181 |
| | DNA deamination mediates innate immunity to retroviral infection | Q28179534 |
| | Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators | Q28203103 |
| | HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages | Q28204428 |
| | The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription | Q28206012 |
| | Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex | Q28210666 |
| | Controlling the elongation phase of transcription with P-TEFb | Q28255518 |
| | A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA | Q28263974 |
| | Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4 | Q28267929 |
| | A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif | Q28276184 |
| | The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA | Q28279502 |
| | Retroviral restriction by APOBEC proteins | Q28290721 |
| | Interaction of Virion Protein Vpr of Human Immunodeficiency Virus Type 1 with Cellular Transcription Factor Sp1 and trans-Activation of Viral Long Terminal Repeat | Q28291807 |
| | The role of Vpr in HIV-1 pathogenesis | Q28301540 |
| | Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection | Q28304773 |
| | A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73 | Q28305429 |
| | Dimerization with PEBP2beta protects RUNX1/AML1 from ubiquitin-proteasome-mediated degradation | Q28348865 |
| | Activation of HIV-1 from latent infection via synergy of RUNX1 inhibitor Ro5-3335 and SAHA | Q28541244 |
| | Bst-2/HM1.24 is a raft-associated apical membrane protein with an unusual topology | Q28580409 |
| | The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA | Q28652351 |
| | The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53 | Q29547773 |
| | Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu | Q29547836 |
| | The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif | Q29618938 |
| | HIV-1 accessory proteins--ensuring viral survival in a hostile environment | Q29619538 |
| | HIV Vpu Interferes with NF-κB Activity but Not with Interferon Regulatory Factor 3. | Q36080904 |
| | Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity | Q36185332 |
| | Functional Segregation of Overlapping Genes in HIV. | Q36226848 |
| | Transcriptional regulation of APOBEC3 antiviral immunity through the CBF-β/RUNX axis | Q36276957 |
| | HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail | Q36322591 |
| | The human immunodeficiency virus type 1 (HIV-1) Vpu protein interferes with an early step in the biosynthesis of major histocompatibility complex (MHC) class I molecules | Q36377062 |
| | Life and death decisions by the E2F transcription factors | Q36499727 |
| | HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells | Q36520900 |
| | Retinoblastoma family proteins as key targets of the small DNA virus oncoproteins. | Q36579274 |
| | The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation | Q36668708 |
| | Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4 | Q36687143 |
| | Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein | Q37104090 |
| | Activation of the DNA Damage Response Is a Conserved Function of HIV-1 and HIV-2 Vpr That Is Independent of SLX4 Recruitment | Q37253817 |
| | Analysis of human immunodeficiency virus type 1 transcriptional elongation in resting CD4+ T cells in vivo | Q37348552 |
| | Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variants | Q37377094 |
| | AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation | Q37475277 |
| | The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongation | Q37506941 |
| | Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation. | Q37574658 |
| | CBFβ enhances de novo protein biosynthesis of its binding partners HIV-1 Vif and RUNX1 and potentiates the Vif-induced degradation of APOBEC3G. | Q37714020 |
| | Mechanisms underlying HIV-1 Vpu-mediated viral egress | Q38211428 |
| | Stimulation of NF-κB activity by the HIV restriction factor BST2. | Q39230459 |
| | Innate sensing of HIV-1 assembly by Tetherin induces NFκB-dependent proinflammatory responses. | Q39243642 |
| | Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo. | Q39270892 |
| | Anti-tetherin activities in Vpu-expressing primate lentiviruses | Q39391944 |
| | Contribution of Vpu, Env, and Nef to CD4 down-modulation and resistance of human immunodeficiency virus type 1-infected T cells to superinfection | Q39593653 |
| | Cell cycle- and Vpr-mediated regulation of human immunodeficiency virus type 1 expression in primary and transformed T-cell lines | Q39594512 |
| | HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment | Q39696123 |
| | HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP | Q39703646 |
| | Antagonism to and intracellular sequestration of human tetherin by the human immunodeficiency virus type 2 envelope glycoprotein | Q39801517 |
| | HIV-1 antagonism of CD317 is species specific and involves Vpu-mediated proteasomal degradation of the restriction factor | Q39872885 |
| | Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR. | Q40118214 |
| | Phosphatidylinositol-(4,5)-bisphosphate enables efficient secretion of HIV-1 Tat by infected T-cells | Q40508633 |
| | Vpr-mediated incorporation of UNG2 into HIV-1 particles is required to modulate the virus mutation rate and for replication in macrophages | Q40564751 |
| | HIV-1 Vpu sequesters beta-transducin repeat-containing protein (betaTrCP) in the cytoplasm and provokes the accumulation of beta-catenin and other SCFbetaTrCP substrates. | Q40625711 |
| | Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R. | Q40649004 |
| | The human immunodeficiency virus type 1 Vpu protein inhibits NF-kappa B activation by interfering with beta TrCP-mediated degradation of Ikappa B. | Q40816820 |
| | Cooperative interaction between HIV-1 regulatory proteins Tat and Vpr modulates transcription of the viral genome | Q40863490 |
| | HIV-1 Vpr increases viral expression by manipulation of the cell cycle: a mechanism for selection of Vpr in vivo | Q41071784 |
| | HIV-1 Rev downregulates Tat expression and viral replication via modulation of NAD(P)H:quinine oxidoreductase 1 (NQO1). | Q41172672 |
| | Vif proteins of human and simian immunodeficiency viruses require cellular CBFβ to degrade APOBEC3 restriction factors | Q41878273 |
| | RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation | Q42027880 |
| | The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein | Q29619540 |
| | Cellular uptake of the tat protein from human immunodeficiency virus | Q29620627 |
| | Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains. | Q30382590 |
| | Activation of the ATR pathway by human immunodeficiency virus type 1 Vpr involves its direct binding to chromatin in vivo | Q33227756 |
| | DDB1 maintains genome integrity through regulation of Cdt1 | Q33255742 |
| | HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase | Q33290831 |
| | HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells | Q33363091 |
| | Human immunodeficiency virus type 1 has an additional coding sequence in the central region of the genome | Q33649232 |
| | Leveraging APOBEC3 proteins to alter the HIV mutation rate and combat AIDS. | Q33654949 |
| | Association of Tat with Promoters of PTEN and PP2A Subunits Is Key to Transcriptional Activation of Apoptotic Pathways in HIV-Infected CD4+ T Cells | Q33700607 |
| | Functional domains within the human immunodeficiency virus type 2 envelope protein required to enhance virus production | Q33737672 |
| | Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complex | Q33835387 |
| | HIV-1 Nef induces proinflammatory state in macrophages through its acidic cluster domain: involvement of TNF alpha receptor associated factor 2. | Q34008771 |
| | Tetherin inhibits HIV-1 release by directly tethering virions to cells | Q34019962 |
| | Lentiviral Vif degrades the APOBEC3Z3/APOBEC3H protein of its mammalian host and is capable of cross-species activity | Q34045987 |
| | RNA-guided assembly of Rev-RRE nuclear export complexes | Q34080345 |
| | Identification of a protein encoded by the vpu gene of HIV-1. | Q34163678 |
| | Feedback regulation of human immunodeficiency virus type 1 expression by the Rev protein | Q34220747 |
| | Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection | Q34242229 |
| | Functional role of human immunodeficiency virus type 1 vpu. | Q34288200 |
| | Structural insights for HIV-1 therapeutic strategies targeting Vif. | Q34433647 |
| | Nef proteins from simian immunodeficiency viruses are tetherin antagonists. | Q34658653 |
| | HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription | Q34896128 |
| | RNA-directed remodeling of the HIV-1 protein Rev orchestrates assembly of the Rev-Rev response element complex | Q35179371 |
| | The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein | Q35211232 |
| | HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages. | Q35234824 |
| | Differential regulation of NF-κB-mediated proviral and antiviral host gene expression by primate lentiviral Nef and Vpu proteins | Q35549043 |
| | Transmembrane domain determinants of CD4 Downregulation by HIV-1 Vpu. | Q35665886 |
| | Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor. | Q35785393 |
| | The viral infectivity factor (Vif) of HIV-1 unveiled | Q35791995 |
| | Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription. | Q35804608 |
| | HIV Rev Assembly on the Rev Response Element (RRE): A Structural Perspective | Q35808679 |
| | The p6gag domain of human immunodeficiency virus type 1 is sufficient for the incorporation of Vpr into heterologous viral particles | Q35838540 |
| | Vpr-induced cell cycle arrest is conserved among primate lentiviruses. | Q35859146 |
| P433 | issue | 1 | |
| P304 | page(s) | 241-260 | |
| P577 | publication date | 2017-09-01 | |
| P1433 | published in | Annual Review of Virology | Q19962702 |
| P1476 | title | Making Sense of Multifunctional Proteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription | |
| P478 | volume | 4 | |