| scholarly article | Q13442814 |
| P50 | author | Michael Emerman | Q89169980 |
| P2093 | author name string | Oliver I Fregoso | |
| P2860 | cites work | Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R. | Q40649004 |
| Hybrid origin of SIV in chimpanzees. | Q52842327 | ||
| Complex Evolutionary History of Primate LentiviralvprGenes | Q57007033 | ||
| Chimpanzee reservoirs of pandemic and nonpandemic HIV-1 | Q22242279 | ||
| Origins of HIV and the AIDS pandemic | Q22242661 | ||
| Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair | Q24313572 | ||
| Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair | Q24314301 | ||
| Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing | Q24318920 | ||
| VprBP has intrinsic kinase activity targeting histone H2A and represses gene transcription | Q24338707 | ||
| SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef | Q24338889 | ||
| HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation | Q24338895 | ||
| Human immunodeficiency virus type 1 Vpr induces the degradation of the UNG and SMUG uracil-DNA glycosylases | Q24530147 | ||
| Simian immunodeficiency virus infection in free-ranging sooty mangabeys (Cercocebus atys atys) from the Taï Forest, Côte d'Ivoire: implications for the origin of epidemic human immunodeficiency virus type 2. | Q24533334 | ||
| Vpr-binding protein antagonizes p53-mediated transcription via direct interaction with H3 tail | Q24594980 | ||
| Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle | Q24680705 | ||
| Evolutionary conflicts between viruses and restriction factors shape immunity | Q27022032 | ||
| Formation of mobile chromatin-associated nuclear foci containing HIV-1 Vpr and VPRBP is critical for the induction of G2 cell cycle arrest | Q27313676 | ||
| Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif | Q28187133 | ||
| The role of Vpr in HIV-1 pathogenesis | Q28301540 | ||
| HIV-1 accessory proteins--ensuring viral survival in a hostile environment | Q29619538 | ||
| Activation of the ATR pathway by human immunodeficiency virus type 1 Vpr involves its direct binding to chromatin in vivo | Q33227756 | ||
| HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase | Q33290831 | ||
| Evidence for a cytopathogenicity determinant in HIV-1 Vpr. | Q34035915 | ||
| DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase | Q34641190 | ||
| Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development | Q34793207 | ||
| Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1. | Q34845553 | ||
| Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance | Q34898909 | ||
| Improved vectors and genome-wide libraries for CRISPR screening | Q35215629 | ||
| Determinants for degradation of SAMHD1, Mus81 and induction of G2 arrest in HIV-1 Vpr and SIVagm Vpr. | Q35684278 | ||
| The host restriction factor APOBEC3G and retroviral Vif protein coevolve due to ongoing genetic conflict | Q35697413 | ||
| FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2 | Q35796778 | ||
| Vpr-induced cell cycle arrest is conserved among primate lentiviruses. | Q35859146 | ||
| Conservation and host specificity of Vpr-mediated cell cycle arrest suggest a fundamental role in primate lentivirus evolution and biology. | Q35886285 | ||
| Vpr of simian immunodeficiency virus of African green monkeys is required for replication in macaque macrophages and lymphocytes. | Q35888756 | ||
| Nuclear import and cell cycle arrest functions of the HIV-1 Vpr protein are encoded by two separate genes in HIV-2/SIV(SM). | Q35914698 | ||
| Importance of vpr for infection of rhesus monkeys with simian immunodeficiency virus. | Q36770468 | ||
| HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages | Q36904912 | ||
| Production of recombinant adeno-associated viral vectors for in vitro and in vivo use. | Q37081220 | ||
| HIV-1 and HIV-2 exhibit divergent interactions with HLTF and UNG2 DNA repair proteins | Q37086412 | ||
| The Evolutionary Histories of Antiretroviral Proteins SERINC3 and SERINC5 Do Not Support an Evolutionary Arms Race in Primates. | Q37224846 | ||
| Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation. | Q37574658 | ||
| In vitro Inactivation of Latent HSV by Targeted Mutagenesis Using an HSV-specific Homing Endonuclease | Q37634060 | ||
| FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair | Q37870047 | ||
| SLX4-SLX1 Protein-independent Down-regulation of MUS81-EME1 Protein by HIV-1 Viral Protein R (Vpr). | Q38761101 | ||
| The SLX4 complex is a SUMO E3 ligase that impacts on replication stress outcome and genome stability | Q38926205 | ||
| G2/M cell cycle arrest correlates with primate lentiviral Vpr interaction with the SLX4 complex. | Q38947343 | ||
| Human infection by genetically diverse SIVSM-related HIV-2 in west Africa | Q39242650 | ||
| Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo. | Q39270892 | ||
| The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx. | Q39405160 | ||
| Reversal of human immunodeficiency virus type 1 IIIB to a neutralization-resistant phenotype in an accidentally infected laboratory worker with a progressive clinical course | Q39605628 | ||
| Universal real-time PCR for the detection and quantification of adeno-associated virus serotype 2-derived inverted terminal repeat sequences | Q39639189 | ||
| ATR couples FANCD2 monoubiquitination to the DNA-damage response | Q39941293 | ||
| P433 | issue | 5 | |
| P921 | main subject | DNA damage | Q5205747 |
| HIV | Q15787 | ||
| P577 | publication date | 2016-09-13 | |
| P1433 | published in | mBio | Q15817061 |
| P1476 | title | Activation of the DNA Damage Response Is a Conserved Function of HIV-1 and HIV-2 Vpr That Is Independent of SLX4 Recruitment | |
| P478 | volume | 7 |
| Q60947014 | A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded Vpx |
| Q38628801 | An Overview of Human Immunodeficiency Virus Type 1-Associated Common Neurological Complications: Does Aging Pose a Challenge? |
| Q47146547 | Are Evolution and the Intracellular Innate Immune System Key Determinants in HIV Transmission? |
| Q92732582 | Distinct MCM10 Proteasomal Degradation Profiles by Primate Lentiviruses Vpr Proteins |
| Q53820052 | HIV-1 Vpr hijacks EDD-DYRK2-DDB1DCAF1 to disrupt centrosome homeostasis. |
| Q96350999 | HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137 |
| Q92511221 | Illuminating the Role of Vpr in HIV Infection of Myeloid Cells |
| Q41927990 | Making Sense of Multifunctional Proteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription |
| Q40062891 | Primate lentiviruses use at least three alternative strategies to suppress NF-κB-mediated immune activation |
| Q64078058 | Promiscuous Targeting of Cellular Proteins by Vpr Drives Systems-Level Proteomic Remodeling in HIV-1 Infection |
| Q47552961 | Structural alteration of DNA induced by viral protein R of HIV-1 triggers the DNA damage response |
| Q42335670 | The KT Jeang Retrovirology prize 2017: Michael Emerman |
| Q40235566 | Virion-Associated Vpr Alleviates a Postintegration Block to HIV-1 Infection of Dendritic Cells. |
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