scholarly article | Q13442814 |
P2093 | author name string | B Matija Peterlin | |
Koh Fujinaga | |||
Daniele C Cary | |||
P2860 | cites work | Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS) | Q22242256 |
Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA. | Q24537283 | ||
The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II | Q24605935 | ||
7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcription | Q24634280 | ||
Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells | Q24644201 | ||
Comparison of 5' and 3' long terminal repeat promoter function in human immunodeficiency virus | Q24646050 | ||
The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA | Q24647541 | ||
Transcriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cure | Q26999858 | ||
A highly purified RNA polymerase II elongation control system | Q28216031 | ||
Regulation of TAK/P-TEFb in CD4+ T lymphocytes and macrophages | Q28253165 | ||
Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy | Q28253761 | ||
A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA | Q28263974 | ||
Pneumocystis pneumonia--Los Angeles | Q28264042 | ||
Exosomes derived from HIV-1-infected cells contain trans-activation response element RNA | Q28290390 | ||
Poly(A) site selection in the HIV-1 provirus: inhibition of promoter-proximal polyadenylation by the downstream major splice donor site | Q71584691 | ||
Host factors regulating post-integration latency of HIV | Q81627002 | ||
The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells | Q28306379 | ||
P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro | Q28379179 | ||
Epigenetic regulation of HIV-1 latency by cytosine methylation | Q28475636 | ||
Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes | Q28487524 | ||
Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing | Q28537694 | ||
An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression | Q28546918 | ||
Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element | Q28646726 | ||
TAK, an HIV Tat-associated kinase, is a member of the cyclin-dependent family of protein kinases and is induced by activation of peripheral blood lymphocytes and differentiation of promonocytic cell lines | Q28647556 | ||
Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro | Q29614788 | ||
Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product | Q29615049 | ||
Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation | Q29615068 | ||
Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy | Q29615993 | ||
Recovery of replication-competent HIV despite prolonged suppression of plasma viremia | Q29615995 | ||
An inducible transcription factor activates expression of human immunodeficiency virus in T cells | Q29618434 | ||
Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells | Q33250088 | ||
HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1. | Q33262230 | ||
Bimolecular fluorescence complementation (BiFC) analysis as a probe of protein interactions in living cells | Q33345889 | ||
Cyclin T1-dependent genes in activated CD4 T and macrophage cell lines appear enriched in HIV-1 co-factors | Q33367106 | ||
Negative elongation factor is required for the maintenance of proviral latency but does not induce promoter-proximal pausing of RNA polymerase II on the HIV long terminal repeat | Q33602605 | ||
Controlling cellular P-TEFb activity by the HIV-1 transcriptional transactivator Tat | Q33728518 | ||
Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation. | Q34057748 | ||
Mutations in the tat gene are responsible for human immunodeficiency virus type 1 postintegration latency in the U1 cell line | Q34070377 | ||
HIV-1 expression within resting CD4+ T cells after multiple doses of vorinostat | Q34106191 | ||
Combination of biological screening in a cellular model of viral latency and virtual screening identifies novel compounds that reactivate HIV-1 | Q34132738 | ||
Transcriptional interference in avian retroviruses—implications for the promoter insertion model of leukaemogenesis | Q34257238 | ||
Human immunodeficiency virus long terminal repeat responds to T-cell activation signals | Q34350307 | ||
Transcriptional interference antagonizes proviral gene expression to promote HIV latency | Q34443670 | ||
Trans-acting transcriptional regulation of human T-cell leukemia virus type III long terminal repeat | Q34563887 | ||
Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies | Q34607763 | ||
Molecular cloning of lymphadenopathy-associated virus | Q34707015 | ||
HIV reproducibly establishes a latent infection after acute infection of T cells in vitro. | Q34985945 | ||
Modulation of a P-TEFb functional equilibrium for the global control of cell growth and differentiation | Q35071358 | ||
The Yin and Yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation | Q35072999 | ||
Characterization of human cyclin-dependent kinase 12 (CDK12) and CDK13 complexes in C-terminal domain phosphorylation, gene transcription, and RNA processing | Q35097083 | ||
Visualization of positive transcription elongation factor b (P-TEFb) activation in living cells | Q35121356 | ||
Human Immunodeficiency Virus-Type 1 LTR DNA contains an intrinsic gene producing antisense RNA and protein products | Q35157534 | ||
Dual role of novel ingenol derivatives from Euphorbia tirucalli in HIV replication: inhibition of de novo infection and activation of viral LTR. | Q35168379 | ||
Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts | Q35202038 | ||
The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein | Q35211232 | ||
Reactivation of latent HIV-1 by new semi-synthetic ingenol esters | Q35252396 | ||
Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations. | Q35720063 | ||
Regulation of cyclin T1 and HIV-1 Replication by microRNAs in resting CD4+ T lymphocytes. | Q35826285 | ||
CDK11 in TREX/THOC Regulates HIV mRNA 3' End Processing | Q36289312 | ||
Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein | Q36332978 | ||
Dynamic regulation of HIV-1 mRNA populations analyzed by single-molecule enrichment and long-read sequencing. | Q36368754 | ||
MicroRNA-mediated restriction of HIV-1 in resting CD4+ T cells and monocytes. | Q36404157 | ||
HDAC inhibitor reduces cytokine storm and facilitates induction of chimerism that reverses lupus in anti-CD3 conditioning regimen. | Q36534267 | ||
Highly potent, synthetically accessible prostratin analogs induce latent HIV expression in vitro and ex vivo | Q37031659 | ||
Reactivation of HIV latency by a newly modified Ingenol derivative via protein kinase Cδ-NF-κB signaling | Q37041173 | ||
Analysis of human immunodeficiency virus type 1 transcriptional elongation in resting CD4+ T cells in vivo | Q37348552 | ||
A point mutation in the HIV-1 Tat responsive element is associated with postintegration latency | Q37518835 | ||
Release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein (snRNP) activates hexamethylene bisacetamide-inducible protein (HEXIM1) transcription. | Q37683410 | ||
New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo. | Q37695001 | ||
Efficient delivery of lentiviral vectors into resting human CD4 T cells | Q37735112 | ||
Dynamic phosphorylation patterns of RNA polymerase II CTD during transcription | Q38043848 | ||
Transcription elongation factors DSIF and NELF: promoter-proximal pausing and beyond | Q38064281 | ||
Reactivation of latent HIV: do all roads go through P-TEFb? | Q38177273 | ||
Procyanidin trimer C1 derived from Theobroma cacao reactivates latent human immunodeficiency virus type 1 provirus | Q38905078 | ||
Histone deacetylase inhibitors (HDACis) that release the positive transcription elongation factor b (P-TEFb) from its inhibitory complex also activate HIV transcription | Q39173861 | ||
Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter. | Q39723092 | ||
Effects of prostratin on T-cell activation and human immunodeficiency virus latency | Q39753161 | ||
CDK13, a new potential human immunodeficiency virus type 1 inhibitory factor regulating viral mRNA splicing | Q39764495 | ||
Detection, characterization and regulation of antisense transcripts in HIV-1. | Q40073362 | ||
The non-coding snRNA 7SK controls transcriptional termination, poising, and bidirectionality in embryonic stem cells | Q40588850 | ||
Casein kinase 2 interacts with cyclin-dependent kinase 11 (CDK11) in vivo and phosphorylates both the RNA polymerase II carboxyl-terminal domain and CDK11 in vitro | Q40622068 | ||
Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes | Q40886843 | ||
P-TEFb as a target to reactivate latent HIV: two Brds are now in hand | Q41641914 | ||
Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure. | Q41880147 | ||
Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation | Q41885967 | ||
Bryostatin-1 synergizes with histone deacetylase inhibitors to reactivate HIV-1 from latency. | Q42968418 | ||
Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough. | Q43226911 | ||
NF-kappaB binds P-TEFb to stimulate transcriptional elongation by RNA polymerase II. | Q43730164 | ||
Recombination: Multiply infected spleen cells in HIV patients | Q43923409 | ||
Negative elongation factor NELF represses human immunodeficiency virus transcription by pausing the RNA polymerase II complex | Q45405018 | ||
Trans-activator gene of human T-lymphotropic virus type III (HTLV-III). | Q45838520 | ||
Nucleotide sequence and expression of an AIDS-associated retrovirus (ARV-2). | Q48381924 | ||
Primordial dwarfism gene maintains Lin28 expression to safeguard embryonic stem cells from premature differentiation. | Q50667759 | ||
Purification of P-TEFb, a transcription factor required for the transition into productive elongation. | Q52539193 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 448-454 | |
P577 | publication date | 2016-01-05 | |
P1433 | published in | Journal of Clinical Investigation | Q3186904 |
P1476 | title | Molecular mechanisms of HIV latency | |
P478 | volume | 126 |
Q51171205 | A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis. |
Q37356604 | Activation of HIV-1 expression in latently infected CD4+ T cells by the small molecule PKC412. |
Q59350537 | Analysis of evolutionary rate of HIV-1 subtype B using blood donor samples in Japan |
Q97885933 | Bromodomain Inhibitors as Therapeutics for Herpesvirus-Related Disease: All BETs Are Off? |
Q90633999 | CRISPR-based gene knockout screens reveal deubiquitinases involved in HIV-1 latency in two Jurkat cell models |
Q95355768 | Chromatin Regulation and the Histone Code in HIV Latency |
Q91733333 | Circulating levels of ATP is a biomarker of HIV cognitive impairment |
Q38995028 | Cyclin-dependent kinases as therapeutic targets for HIV-1 infection. |
Q40053061 | Differentiating Immune Cell Targets in Gut-Associated Lymphoid Tissue for HIV Cure. |
Q99713341 | Effect of Opioid Use on Immune Activation and HIV Persistence on ART |
Q36224979 | Euphorbia Kansui Reactivates Latent HIV. |
Q59352479 | G-Quadruplexes: More Than Just a Kink in Microbial Genomes |
Q59349903 | Galectin-3 is involved in HIV-1 expression through NF-κB activation and associated with Tat in latently infected cells |
Q58612091 | HEXIM1-Tat chimera inhibits HIV-1 replication |
Q93023822 | HIV Silencing and Inducibility Are Heterogeneous and Are Affected by Factors Intrinsic to the Virus |
Q52577483 | HIV Tat/P-TEFb Interaction: A Potential Target for Novel Anti-HIV Therapies. |
Q64118463 | HIV infection and latency induce a unique metabolic signature in human macrophages |
Q39134277 | HIV-1 Tat and Viral Latency: What We Can Learn from Naturally Occurring Sequence Variations. |
Q41921236 | HIV-infected macrophages and microglia that survive acute infection become viral reservoirs by a mechanism involving Bim. |
Q36515124 | Hematopoietic stem cell transplantation for HIV cure |
Q56962083 | Identification of Novel HIV-1 Latency-Reversing Agents from a Library of Marine Natural Products |
Q59351694 | Identification, Localization, and Quantification of HIV Reservoirs Using Microscopy |
Q93000948 | Immune Control of HIV |
Q36758540 | Intradermal injection of a Tat Oyi-based therapeutic HIV vaccine reduces of 1.5 log copies/mL the HIV RNA rebound median and no HIV DNA rebound following cART interruption in a phase I/II randomized controlled clinical trial. |
Q38800533 | Kill: boosting HIV-specific immune responses |
Q57042525 | Lymphatic endothelial cells promote productive and latent HIV infection in resting CD4+ T cells |
Q92134571 | Measuring the Success of HIV-1 Cure Strategies |
Q37512889 | Naf1 Regulates HIV-1 Latency by Suppressing Viral Promoter-Driven Gene Expression in Primary CD4+ T Cells. |
Q58862085 | Natural product-derived compounds in HIV suppression, remission, and eradication strategies |
Q46187533 | Natural products and HIV/AIDS. |
Q92456736 | New targets for HIV drug discovery |
Q97067038 | Novel Histone Deacetylase Inhibitors and HIV-1 Latency-Reversing Agents Identified by Large-Scale Virtual Screening |
Q89782162 | P-TEFb as A Promising Therapeutic Target |
Q90079629 | Potential of the NKG2D/NKG2DL Axis in NK Cell-Mediated Clearance of the HIV-1 Reservoir |
Q38928538 | Primate Lentiviruses Modulate NF-κB Activity by Multiple Mechanisms to Fine-Tune Viral and Cellular Gene Expression |
Q59811612 | Procyanidin trimer C1 reactivates latent HIV as a triple combination therapy with kansui and JQ1 |
Q39315697 | Proviral Latency, Persistent Human Immunodeficiency Virus Infection, and the Development of Latency Reversing Agents. |
Q36515170 | Recent developments in the effort to cure HIV infection: going beyond N = 1. |
Q89659572 | Reduce and Control: A Combinatorial Strategy for Achieving Sustained HIV Remissions in the Absence of Antiretroviral Therapy |
Q55282742 | SUN2 Modulates HIV-1 Infection and Latency through Association with Lamin A/C To Maintain the Repressive Chromatin. |
Q59359386 | Scaffold attachment factor B suppresses HIV-1 infection of CD4 T cells by preventing binding of RNA polymerase II to HIV-1's long terminal repeat |
Q93010915 | Specific Activation In Vivo of HIV-1 by a Bromodomain Inhibitor from Monocytic Cells in Humanized Mice under Antiretroviral Therapy |
Q92216465 | Strength of T cell signaling regulates HIV-1 replication and establishment of latency |
Q56987882 | Suppression of NF-κB Activity: A Viral Immune Evasion Mechanism |
Q54210140 | Targeting the Latent Reservoir for HIV-1. |
Q59360694 | The BET bromodomain inhibitor apabetalone induces apoptosis of latent HIV-1 reservoir cells following viral reactivation |
Q55486269 | The Neuropeptides Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-Activating Polypeptide Control HIV-1 Infection in Macrophages Through Activation of Protein Kinases A and C. |
Q55514032 | The RNA surveillance proteins UPF1, UPF2 and SMG6 affect HIV-1 reactivation at a post-transcriptional level. |
Q39153976 | The therapeutic landscape of HIV-1 via genome editing |
Q38707836 | Transcriptional Elongation of HSV Immediate Early Genes by the Super Elongation Complex Drives Lytic Infection and Reactivation from Latency |
Q47160966 | Tunneling nanotubes (TNT) mediate long-range gap junctional communication: Implications for HIV cell to cell spread |
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