scholarly article | Q13442814 |
P50 | author | Andrew P Rice | Q55277928 |
P2093 | author name string | Sona Budhiraja | |
P2860 | cites work | Antiretroviral intensification and valproic acid lack sustained effect on residual HIV-1 viremia or resting CD4+ cell infection | Q21142645 |
Translating the Histone Code | Q22065840 | ||
Selective inhibition of BET bromodomains | Q24301009 | ||
Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression | Q24301464 | ||
The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription | Q24316236 | ||
Active nuclear import of human immunodeficiency virus type 1 preintegration complexes | Q24564507 | ||
Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid | Q24596282 | ||
7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcription | Q24634280 | ||
Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells | Q24644201 | ||
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription | Q24672881 | ||
HIV-1 eradication strategies: design and assessment | Q26864933 | ||
Depletion of latent HIV-1 infection in vivo: a proof-of-concept study | Q28111910 | ||
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes | Q28116607 | ||
The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription | Q28206012 | ||
Regulation of TAK/P-TEFb in CD4+ T lymphocytes and macrophages | Q28253165 | ||
Controlling the elongation phase of transcription with P-TEFb | Q28255518 | ||
Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4 | Q28267929 | ||
HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure | Q28283258 | ||
Low levels of deoxynucleotides in peripheral blood lymphocytes: a strategy to inhibit human immunodeficiency virus type 1 replication | Q28368051 | ||
The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis | Q29618035 | ||
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation | Q29619611 | ||
Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection | Q29619738 | ||
HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription | Q30835037 | ||
Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection | Q33476165 | ||
Chemokines and their receptors in lymphocyte traffic and HIV infection | Q33799800 | ||
Transcriptional and posttranscriptional regulation of HIV-1 gene expression | Q34030804 | ||
BET bromodomain inhibition as a novel strategy for reactivation of HIV-1 | Q34032827 | ||
Adverse effects of antiretroviral therapy | Q34071132 | ||
Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity | Q34123595 | ||
Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV-1 reservoirs: results from a multicentre randomized clinical study. | Q34249596 | ||
Phosphatase PPM1A negatively regulates P-TEFb function in resting CD4(+) T cells and inhibits HIV-1 gene expression | Q42112998 | ||
Prostratin antagonizes HIV latency by activating NF-kappaB. | Q43551279 | ||
NF-kappaB binds P-TEFb to stimulate transcriptional elongation by RNA polymerase II. | Q43730164 | ||
Prolonged valproic acid treatment does not reduce the size of latent HIV reservoir | Q46558493 | ||
OKT3 and IL-2 treatment for purging of the latent HIV-1 reservoir in vivo results in selective long-lasting CD4+ T cell depletion. | Q52019286 | ||
In vivo fate of HIV-1-infected T cells: quantitative analysis of the transition to stable latency. | Q52050894 | ||
Histone deacetylase inhibitors potently repress CXCR4 chemokine receptor expression and function in acute lymphoblastic leukaemia | Q57218660 | ||
Increased association of 7SK snRNA with Tat cofactor P-TEFb following activation of peripheral blood lymphocytes | Q79254743 | ||
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy | Q34290545 | ||
You bet-cha: a novel family of transcriptional regulators | Q34327293 | ||
The molecular biology of HIV latency: breaking and restoring the Tat-dependent transcriptional circuit | Q34544409 | ||
HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription | Q34896128 | ||
HIV-1 pathogenesis | Q35166833 | ||
Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription. | Q35804608 | ||
Regulation of cyclin T1 and HIV-1 Replication by microRNAs in resting CD4+ T lymphocytes. | Q35826285 | ||
HIV Restriction Factors and Mechanisms of Evasion | Q35902681 | ||
Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein | Q36332978 | ||
MicroRNA-mediated restriction of HIV-1 in resting CD4+ T cells and monocytes. | Q36404157 | ||
Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation | Q36409885 | ||
The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic acid for latent HIV-1 expression in vitro | Q36501927 | ||
PP2B and PP1alpha cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling | Q36649160 | ||
The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation | Q36668708 | ||
HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression | Q36781531 | ||
DNase I-hypersensitive sites are associated with both long terminal repeats and with the intragenic enhancer of integrated human immunodeficiency virus type 1 | Q36828450 | ||
Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II | Q37103512 | ||
Suberoylanilide hydroxamic acid induces limited changes in the transcriptome of primary CD4(+) T cells. | Q37119662 | ||
A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression | Q37192141 | ||
Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors | Q37257484 | ||
The challenge of finding a cure for HIV infection | Q37407598 | ||
Characterization of Cdk9 T-loop phosphorylation in resting and activated CD4(+) T lymphocytes. | Q37429329 | ||
Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs | Q37615893 | ||
Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies | Q37644561 | ||
Host proteins involved in HIV infection: new therapeutic targets. | Q37657826 | ||
Facts and fiction: cellular models for high throughput screening for HIV-1 reactivating drugs | Q37972644 | ||
HIV latency | Q37974218 | ||
Reactivation of latent HIV by histone deacetylase inhibitors. | Q38091753 | ||
Effects of prostratin on Cyclin T1/P-TEFb function and the gene expression profile in primary resting CD4+ T cells | Q38557763 | ||
Histone deacetylase inhibitors (HDACis) that release the positive transcription elongation factor b (P-TEFb) from its inhibitory complex also activate HIV transcription | Q39173861 | ||
Reactivation of latent HIV-1 by inhibition of BRD4. | Q39264882 | ||
Molecular characterization of preintegration latency in human immunodeficiency virus type 1 infection | Q39686599 | ||
HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP | Q39703646 | ||
Cellular APOBEC3G restricts HIV-1 infection in resting CD4+ T cells | Q40435387 | ||
Kinetics of human immunodeficiency virus type 1 decay following entry into resting CD4+ T cells | Q40976774 | ||
BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism. | Q41641646 | ||
Cyclin T1 and CDK9 T-loop phosphorylation are downregulated during establishment of HIV-1 latency in primary resting memory CD4+ T cells. | Q42052356 | ||
P433 | issue | 7 | |
P577 | publication date | 2013-07-01 | |
P1433 | published in | Future Virology | Q15751230 |
P1476 | title | Reactivation of latent HIV: do all roads go through P-TEFb? | |
P478 | volume | 8 |
Q40391119 | Assays for precise quantification of total (including short) and elongated HIV-1 transcripts. |
Q38213132 | Biologically active diterpenes containing a gem-dimethylcyclopropane subunit: an intriguing source of PKC modulators |
Q38862056 | Challenges and strategies for the eradication of the HIV reservoir |
Q90055320 | DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTR |
Q91617582 | Effect of transcription inhibition and generation of suppressive viral non-coding RNAs |
Q63246720 | Enhancement of adenovirus infection and adenoviral vector-mediated gene delivery by bromodomain inhibitor JQ1 |
Q38271132 | HIV eradication: combinatorial approaches to activate latent viruses |
Q40473076 | Heat Shock Protein 90 Facilitates Latent HIV Reactivation through Maintaining the Function of Positive Transcriptional Elongation Factor b (p-TEFb) under Proteasome Inhibition. |
Q93126280 | Insights into the HIV Latency and the Role of Cytokines |
Q36030989 | Leveraging Cancer Therapeutics for the HIV Cure Agenda: Current Status and Future Directions |
Q33815611 | Mechanisms of HIV Transcriptional Regulation by Drugs of Abuse |
Q36515063 | Molecular mechanisms of HIV latency |
Q59360694 | The BET bromodomain inhibitor apabetalone induces apoptosis of latent HIV-1 reservoir cells following viral reactivation |
Q36790027 | The BET inhibitor OTX015 reactivates latent HIV-1 through P-TEFb |
Q47098415 | The bromodomain and extraterminal domain inhibitor bromosporine synergistically reactivates latent HIV-1 in latently infected cells. |
Q36906001 | The effects of cocaine on HIV transcription |
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