Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR.

scientific article published on 22 May 2008

Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1051677189
P356DOI10.1186/1742-4690-5-40
P8608Fatcat IDrelease_fgfk4ohyencufafmp6tbelimsq
P932PMC publication ID2412914
P698PubMed publication ID18498648
P5875ResearchGate publication ID5329767

P50authorFatah KashanchiQ91617579
Kylene Kehn-HallQ37837531
P2093author name stringDavid E Symer
Rachel Van Duyne
Zachary Klase
Weilin Wu
Caitlin Pedati
Elizabeth K Flynn
Rebecca Easley
Reem Berro
P2860cites workProtein methylation is required to maintain optimal HIV-1 infectivityQ21245198
The tripartite motif family identifies cell compartmentsQ24291183
The histone chaperone protein Nucleosome Assembly Protein-1 (hNAP-1) binds HIV-1 Tat and promotes viral transcriptionQ24307870
Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activatorsQ24309765
The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cellsQ24336175
In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylationQ24529080
Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcriptionQ24534441
Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongationQ24537588
Methylation of Tat by PRMT6 regulates human immunodeficiency virus type 1 gene expressionQ24558697
In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factorQ24655901
Arginine methylation of the human immunodeficiency virus type 1 Tat protein by PRMT6 negatively affects Tat Interactions with both cyclin T1 and the Tat transactivation regionQ24672150
In vitro interaction of the human immunodeficiency virus type 1 Tat transactivator and the general transcription factor TFIIB with the cellular protein TAPQ24675459
Interaction of human immunodeficiency virus type 1 Tat with a unique site of TFIID inhibits negative cofactor Dr1 and stabilizes the TFIID-TFIIA complexQ24681921
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteinsQ24685694
The SET-domain protein superfamily: protein lysine methyltransferasesQ24811144
Tat gets the "green" light on transcription initiationQ24815711
Intracytoplasmic maturation of the human immunodeficiency virus type 1 reverse transcription complexes determines their capacity to integrate into chromatinQ25256895
Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tailQ27638012
Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomainsQ27641772
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteinsQ27860456
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domainQ27860477
Signaling to chromatin through histone modificationsQ28142598
Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histonesQ28143943
A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoterQ28190014
Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNAQ28203201
Hetero-oligomerization among the TIF family of RBCC/TRIM domain-containing nuclear cofactors: a potential mechanism for regulating the switch between coactivation and corepressionQ28208645
SNFing HIV transcriptionQ38253738
Analysis of Tat transactivation of human immunodeficiency virus transcription in vitro.Q41079020
TAR and Sp1-independent transactivation of HIV long terminal repeat by the Tat protein in the presence of human cytomegalovirus IE1/IE2.Q41122096
HIV-1 Tat protein can transactivate a heterologous TATAA element independent of viral promoter sequences and the trans-activation response elementQ41130969
Suv39H1 and HP1gamma are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latencyQ42100247
HIV-1 tat transcriptional activity is regulated by acetylationQ42163503
HP1 binding to chromatin methylated at H3K9 is enhanced by auxiliary factorsQ42951883
Identification of novel histone post-translational modifications by peptide mass fingerprintingQ44561152
Effects of tethering HP1 to euchromatic regions of the Drosophila genome.Q52604132
Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activityQ63351469
Evidence for Functional Interaction between the HIV-1 Tat Transactivator and the TATA Box Binding Proteinin VivoQ71871314
Antibodies against the folding domain of histone H5 cross-react with H1(0) but not with H1Q72673749
Direct interaction of human TFIID with the HIV-1 transactivator tatQ28250314
A Novel CDK9-Associated C-Type Cyclin Interacts Directly with HIV-1 Tat and Mediates Its High-Affinity, Loop-Specific Binding to TAR RNAQ28263974
HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factorsQ28298100
Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexesQ28304889
The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18Q28509358
Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3Q28609869
Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylationQ29614524
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assemblyQ29614718
Histone and chromatin cross-talkQ29617179
Heterochromatin and epigenetic control of gene expressionQ29618486
HIV-1 Tat protein increases transcriptional initiation and stabilizes elongationQ29620799
Methylation of histone H3 at lysine 4 is highly conserved and correlates with transcriptionally active nuclei in TetrahymenaQ30304568
Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3.Q30307942
HIV-1 Tat protein trans-activates transcription in vitroQ30411837
A real-time view of the TAR:Tat:P-TEFb complex at HIV-1 transcription sitesQ30479706
Acetylated Tat regulates human immunodeficiency virus type 1 splicing through its interaction with the splicing regulator p32.Q33236503
Multifaceted activities of the HIV-1 transactivator of transcription, Tat.Q33743566
Transcriptional repression of euchromatic genes by Drosophila heterochromatin protein 1 and histone modifiersQ33944585
TAR RNA loop: a scaffold for the assembly of a regulatory switch in HIV replicationQ34030432
Re-SET-ting heterochromatin by histone methyltransferasesQ34253201
SET domain proteins modulate chromatin domains in eu- and heterochromatin.Q34458687
Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapyQ34714816
HIV reproducibly establishes a latent infection after acute infection of T cells in vitro.Q34985945
Effect of SWI/SNF chromatin remodeling complex on HIV-1 Tat activated transcriptionQ35040154
Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcriptionQ35131134
Nuclear organization and the control of HIV-1 transcriptionQ35631972
Methylation: a regulator of HIV-1 replication?Q35633276
Chromatin remodeling and modification during HIV-1 Tat-activated transcriptionQ35716781
Nuclear Factor 90(NF90) targeted to TAR RNA inhibits transcriptional activation of HIV-1.Q35874904
Electroporation of viral transactivator proteins into lymphocyte suspension cellsQ35927699
HIV-1 Tat protein promotes formation of more-processive elongation complexesQ35937536
Inhibition of HIV-1 replication by P-TEFb inhibitors DRB, seliciclib and flavopiridol correlates with release of free P-TEFb from the large, inactive form of the complexQ35940053
The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongationQ37506941
P304page(s)40
P577publication date2008-05-22
P1433published inRetrovirologyQ15793508
P1476titleLysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR.
P478volume5

Reverse relations

cites work (P2860)
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