scholarly article | Q13442814 |
P2093 | author name string | Frank J Rauscher | |
Kasirajan Ayyanathan | |||
Gerd G Maul | |||
David C Schultz | |||
Dmitri Negorev | |||
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Comparative analysis of KRAB zinc finger proteins in rodents and man: evidence for several evolutionarily distinct subfamilies of KRAB zinc finger genes | Q51089777 | ||
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Translating the Histone Code | Q22065840 | ||
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KAP-1, a novel corepressor for the highly conserved KRAB repression domain | Q24317676 | ||
BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression | Q24321439 | ||
The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4 | Q24536072 | ||
Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essential | Q24551928 | ||
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Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation | Q24672514 | ||
A family of chromatin remodeling factors related to Williams syndrome transcription factor | Q24673669 | ||
Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail | Q27638012 | ||
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins | Q27860456 | ||
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain | Q27860477 | ||
The language of covalent histone modifications | Q27860931 | ||
COMPASS: a complex of proteins associated with a trithorax-related SET domain protein | Q27931344 | ||
SET1, a yeast member of the trithorax family, functions in transcriptional silencing and diverse cellular processes | Q27939597 | ||
Regulation of transcription by a protein methyltransferase | Q28138085 | ||
Biochemical analysis of the Kruppel-associated box (KRAB) transcriptional repression domain | Q28140601 | ||
Signaling to chromatin through histone modifications | Q28142598 | ||
Assignment of a novel bifurcated SET domain gene, SETDB1, to human chromosome band 1q21 by in situ hybridization and radiation hybrids | Q28144658 | ||
Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3 | Q28214048 | ||
Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae | Q28343956 | ||
A homeotic mutation in the trithorax SET domain impedes histone binding | Q28349462 | ||
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly | Q29614718 | ||
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability | Q29620365 | ||
Rb targets histone H3 methylation and HP1 to promoters | Q29620452 | ||
Transitions in distinct histone H3 methylation patterns at the heterochromatin domain boundaries | Q29622865 | ||
Methylation of histone H3 at lysine 4 is highly conserved and correlates with transcriptionally active nuclei in Tetrahymena | Q30304568 | ||
Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3. | Q30307942 | ||
An embarrassment of niches: the many covalent modifications of histones in transcriptional regulation. | Q34290234 | ||
Nuclear redistribution of BRCA1 during viral infection | Q41006459 | ||
Analysis of chromatin structure by in vivo formaldehyde cross-linking. | Q41132202 | ||
A histone H3 methyltransferase controls DNA methylation in Neurospora crassa | Q42664087 | ||
Hormone-dependent tumor regression in vivo by an inducible transcriptional repressor directed at the PAX3-FKHR oncogene | Q42834438 | ||
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | gene silencing | Q1431332 |
P304 | page(s) | 919-32 | |
P577 | publication date | 2002-04-15 | |
P1433 | published in | Genes & Development | Q1524533 |
P1476 | title | SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins | |
P478 | volume | 16 |
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Q36742450 | Histone modifications and chromatin dynamics: a focus on filamentous fungi |
Q39170765 | Histones Are Rapidly Loaded onto Unintegrated Retroviral DNAs Soon after Nuclear Entry |
Q40022345 | Holocarboxylase synthetase interacts physically with euchromatic histone-lysine N-methyltransferase, linking histone biotinylation with methylation events |
Q42551273 | Holocarboxylase synthetase synergizes with methyl CpG binding protein 2 and DNA methyltransferase 1 in the transcriptional repression of long-terminal repeats |
Q36687748 | Host restriction factors blocking retroviral replication |
Q24563451 | Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes |
Q27934187 | Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells |
Q34212695 | Human factors and pathways essential for mediating epigenetic gene silencing. |
Q38743878 | Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2. |
Q24298944 | ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation |
Q28513885 | Identification and characterization of ZFP-57, a novel zinc finger transcription factor in the mammalian peripheral nervous system |
Q34445102 | Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase |
Q33929209 | Identification of DIM-7, a protein required to target the DIM-5 H3 methyltransferase to chromatin |
Q50351898 | Identification of Shared Molecular Signatures Indicate the Susceptibility of Endometriosis to Multiple Sclerosis |
Q33514240 | Identification of a functional network of human epigenetic silencing factors |
Q42801796 | Identification of a novel Krüppel-associated box domain protein, Krim-1, that interacts with c-Myc and inhibits its oncogenic activity |
Q52020343 | Identification of three histone methyltransferases in Drosophila: dG9a is a suppressor of PEV and is required for gene silencing |
Q48311167 | Identifying Novel Enhancer Elements with CRISPR-Based Screens. |
Q47389543 | Impact of Xist RNA on chromatin modifications and transcriptional silencing maintenance at different stages of imprinted X chromosome inactivation in vole Microtus levis. |
Q35534127 | In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions |
Q24529080 | In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation |
Q37460085 | In vivo gene regulation using tetracycline-regulatable systems |
Q36558145 | Inactivation of a human kinetochore by specific targeting of chromatin modifiers |
Q33637083 | Induction of 11β-HSD 1 and activation of distinct mineralocorticoid receptor- and glucocorticoid receptor-dependent gene networks in decidualizing human endometrial stromal cells |
Q38831555 | Inhibition of EHMT2 Induces a Robust Antiviral Response Against Foot-and-Mouth Disease and Vesicular Stomatitis Virus Infections in Bovine Cells. |
Q33743831 | Inhibition of KAP1 enhances hypoxia-induced Kaposi's sarcoma-associated herpesvirus reactivation through RBP-Jκ. |
Q58797765 | Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma |
Q38610600 | Inhibition of transcription and DNA replication by the papillomavirus E8-E2C protein is mediated by interaction with corepressor molecules |
Q42182620 | Interaction of SET domains with histones and nucleic acid structures in active chromatin. |
Q24300478 | Interactions of ErbB4 and Kap1 Connect the Growth Factor and DNA Damage Response Pathways |
Q84071295 | Interactions of Transcription Factors with Chromatin |
Q28680737 | Interplay between chromatin state, regulator binding, and regulatory motifs in six human cell types |
Q33994811 | Interplay of TRIM28 and DNA methylation in controlling human endogenous retroelements |
Q36788865 | Intersection of nuclear receptors and the proteasome on the epigenetic landscape |
Q33652604 | Introduction--Epiphanies in epigenetics. |
Q40392178 | Involvement of HP1alpha protein in irreversible transcriptional inactivation by antiestrogens in breast cancer cells. |
Q33883423 | Involvement of histone H3 lysine 9 (H3K9) methyltransferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX01294. |
Q39173734 | Involvement of histone methyltransferase GLP in HIV-1 latency through catalysis of H3K9 dimethylation |
Q34181321 | Isoform-specific Intermolecular Disulfide Bond Formation of Heterochromatin Protein 1 (HP1) |
Q64236643 | It Takes a Team: A Gain-of-function Story of p53-R249S |
Q35668901 | Jarid2 (Jumonji, AT rich interactive domain 2) regulates NOTCH1 expression via histone modification in the developing heart |
Q35532757 | KAP1 Deacetylation by SIRT1 Promotes Non-Homologous End-Joining Repair |
Q36434260 | KAP1 Is a Host Restriction Factor That Promotes Human Adenovirus E1B-55K SUMO Modification |
Q52718550 | KAP1 Regulates Regulatory T Cell Function and Proliferation in Both Foxp3-Dependent and -Independent Manners |
Q57549469 | KAP1 facilitates reinstatement of heterochromatin after DNA replication |
Q42657934 | KAP1 is a Novel Substrate for the Arginine Methyltransferase PRMT5. |
Q92708333 | KAP1 is an antiparallel dimer with a functional asymmetry |
Q34979737 | KAP1 promotes proliferation and metastatic progression of breast cancer cells |
Q37886421 | KAP1 protein: an enigmatic master regulator of the genome |
Q27319505 | KAP1 regulates gene networks controlling T-cell development and responsiveness. |
Q36931943 | KAP1 regulates gene networks controlling mouse B-lymphoid cell differentiation and function. |
Q89754582 | KAP1 targets actively transcribed genomic loci to exert pleomorphic effects on RNA polymerase II activity |
Q26822740 | KAPtain in charge of multiple missions: Emerging roles of KAP1 |
Q34568487 | KRAB can repress lentivirus proviral transcription independently of integration site |
Q46327518 | KRAB zinc finger proteins. |
Q38920949 | KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks |
Q43078740 | KRAB zinc-finger proteins localise to novel KAP1-containing foci that are adjacent to PML nuclear bodies. |
Q37065382 | KRAB-Zinc Finger Proteins: A Repressor Family Displaying Multiple Biological Functions. |
Q24792646 | KRAB-containing zinc-finger repressor proteins |
Q39859206 | KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis. |
Q96031505 | KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage |
Q28473103 | KRAB-zinc finger proteins and KAP1 can mediate long-range transcriptional repression through heterochromatin spreading |
Q43079558 | Kaposi's Sarcoma-Associated Herpesvirus Kaposin B Induces Unique Monophosphorylation of STAT3 at Serine 727 and MK2-Mediated Inactivation of the STAT3 Transcriptional Repressor TRIM28 |
Q33744019 | Kaposi's sarcoma-associated herpesvirus-encoded LANA interacts with host KAP1 to facilitate establishment of viral latency |
Q41854713 | Kinetics and epigenetics of retroviral silencing in mouse embryonic stem cells defined by deletion of the D4Z4 element |
Q38201977 | Kruppel-associated box (KRAB) proteins in the adaptive immune system |
Q37317681 | Kruppel-associated box domain-associated protein-1 as a latency regulator for Kaposi's sarcoma-associated herpesvirus and its modulation by the viral protein kinase |
Q35844907 | LIN-61, one of two Caenorhabditis elegans malignant-brain-tumor-repeat-containing proteins, acts with the DRM and NuRD-like protein complexes in vulval development but not in certain other biological processes |
Q42103716 | LINEing germ and embryonic stem cells' silencing of retrotransposons |
Q33791296 | Ligand-dependent corepressor contributes to transcriptional repression by C2H2 zinc-finger transcription factor ZBRK1 through association with KRAB-associated protein-1. |
Q35875136 | Lineage-specific expansion of KRAB zinc-finger transcription factor genes: implications for the evolution of vertebrate regulatory networks |
Q37300571 | Linking Heterochromatin Protein 1 (HP1) to cancer progression |
Q48121278 | LncRNA HOTAIR promotes cell migration and invasion by regulating MKL1 via inhibition miR206 expression in HeLa cells. |
Q58787366 | Loss of SETDB1 decompacts the inactive X chromosome in part through reactivation of an enhancer in the IL1RAPL1 gene |
Q34977115 | Loss of ZBRK1 contributes to the increase of KAP1 and promotes KAP1-mediated metastasis and invasion in cervical cancer |
Q37618942 | Loss of maternal Trim28 causes male-predominant early embryonic lethality |
Q33994806 | Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency |
Q24669780 | Loss-of-function mutations in euchromatin histone methyl transferase 1 (EHMT1) cause the 9q34 subtelomeric deletion syndrome |
Q36699534 | Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR. |
Q24675122 | Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association |
Q26996661 | MBD2 and MBD3: elusive functions and mechanisms |
Q34016183 | MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation |
Q35092329 | MHC class II regulation by epigenetic agents and microRNAs |
Q26765418 | Maintaining memory of silencing at imprinted differentially methylated regions |
Q99415024 | MasterPATH: network analysis of functional genomics screening data |
Q35987178 | Maternal Setdb1 Is Required for Meiotic Progression and Preimplantation Development in Mouse |
Q24338285 | Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet |
Q53587019 | Meisetz and the birth of the KRAB motif |
Q34747001 | Metastasis-associated protein ribosomal RNA processing 1 homolog B (RRP1B) modulates metastasis through regulation of histone methylation |
Q28278522 | Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly |
Q38451083 | Methyl-CpG-binding domain proteins: readers of the epigenome |
Q30309950 | Methylation of histone h3 at lysine 9 targets programmed DNA elimination in tetrahymena |
Q36557362 | Methylomics analysis identifies ZNF671 as an epigenetically repressed novel tumor suppressor and a potential non-invasive biomarker for the detection of urothelial carcinoma. |
Q46677250 | MicroRNA-93 Regulates Hypoxia-Induced Autophagy by Targeting ULK1. |
Q41936508 | Microduplication of Xp11.23p11.3 with effects on cognition, behavior, and craniofacial development |
Q36956834 | Mitochondrial Stress Induces Chromatin Reorganization to Promote Longevity and UPR(mt). |
Q37845655 | Molecular coupling of DNA methylation and histone methylation |
Q42525446 | Monoallele deletion of CBP leads to pericentromeric heterochromatin condensation through ESET expression and histone H3 (K9) methylation |
Q41902696 | Multiparameter functional diversity of human C2H2 zinc finger proteins. |
Q37152690 | Multiple SET methyltransferases are required to maintain normal heterochromatin domains in the genome of Drosophila melanogaster |
Q24532155 | Mutations in the ZNF41 gene are associated with cognitive deficits: identification of a new candidate for X-linked mental retardation |
Q45183912 | Mutations in the heterochromatin protein 1 (HP1) hinge domain affect HP1 protein interactions and chromosomal distribution |
Q24547306 | NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression |
Q42690788 | Neuroepigenetic mechanisms in disease |
Q44491438 | Novel Drosophila heterochromatin protein 1 (HP1)/origin recognition complex-associated protein (HOAP) repeat motif in HP1/HOAP interactions and chromocenter associations |
Q36412174 | Nuclear domain 10-associated proteins recognize and segregate intranuclear DNA/protein complexes to negate gene expression |
Q34189419 | Oligomerization of transcriptional intermediary factor 1 regulators and interaction with ZNF74 nuclear matrix protein revealed by bioluminescence resonance energy transfer in living cells |
Q91644556 | On the relations of phase separation and Hi-C maps to epigenetics |
Q38102573 | On your histone mark, SET, methylate! |
Q34759375 | Opposing ISWI- and CHD-class chromatin remodeling activities orchestrate heterochromatic DNA repair |
Q37336939 | Optimizing sgRNA position markedly improves the efficiency of CRISPR/dCas9-mediated transcriptional repression |
Q55039489 | PAF1 complex interactions with SETDB1 mediate promoter H3K9 methylation and transcriptional repression of Hoxa9 and Meis1 in acute myeloid leukemia. |
Q36206842 | PEG3 Interacts with KAP1 through KRAB-A. |
Q24303619 | PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing |
Q43040885 | PHF8 is a histone H3K9me2 demethylase regulating rRNA synthesis. |
Q40329969 | PML-associated repressor of transcription (PAROT), a novel KRAB-zinc finger repressor, is regulated through association with PML nuclear bodies |
Q42612084 | PPAR-gamma Signaling Crosstalk in Mesenchymal Stem Cells |
Q28247014 | PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing |
Q34116913 | PU.1 inhibits the erythroid program by binding to GATA-1 on DNA and creating a repressive chromatin structure |
Q26995208 | Partners in crime: The role of tandem modules in gene transcription |
Q34270424 | Paternally expressed Peg3 controls maternally expressed Zim1 as a trans factor |
Q42182193 | Phosphoproteomic analysis reveals that PP4 dephosphorylates KAP-1 impacting the DNA damage response |
Q33347938 | Phosphorylation at Ser473 regulates heterochromatin protein 1 binding and corepressor function of TIF1beta/KAP1. |
Q36929141 | Phosphorylation of KRAB-associated Protein 1 (KAP1) at Tyr-449, Tyr-458, and Tyr-517 by Nuclear Tyrosine Kinases Inhibits the Association of KAP1 and Heterochromatin Protein 1α (HP1α) with Heterochromatin |
Q40044888 | Physical and functional interactions between STAT3 and KAP1. |
Q37996525 | Pluripotency and Nuclear Reprogramming |
Q34297995 | Polycomb repressive complex 2 and H3K27me3 cooperate with H3K9 methylation to maintain heterochromatin protein 1α at chromatin |
Q38725574 | Position-effect variegation revisited: HUSHing up heterochromatin in human cells. |
Q99407750 | Primate-restricted KRAB zinc finger proteins and target retrotransposons control gene expression in human neurons |
Q36540170 | Primer binding site-dependent restriction of murine leukemia virus requires HP1 binding by TRIM28. |
Q41077260 | Profile of histone lysine methylation across transcribed mammalian chromatin |
Q35661433 | Protein phosphatase 2A activity affects histone H3 phosphorylation and transcription in Drosophila melanogaster |
Q39737989 | Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET. |
Q34139275 | Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase |
Q51023875 | Purification of histone methyltransferases from HeLa cells |
Q59323656 | RETRACTED ARTICLE: DDB1 and Cul4 are necessary for gene silencing and heterochromatin formation at pericentromeric regions in Neurospora |
Q91942270 | Rapid embryonic cell cycles defer the establishment of heterochromatin by Eggless/SetDB1 in Drosophila |
Q21563368 | Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength |
Q38022419 | Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography |
Q37106147 | Recruitment and Biological Consequences of Histone Modification of H3K27me3 and H3K9me3 |
Q35167221 | Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise |
Q42817808 | Regulated nuclear entry of over‐expressed Setdb1 |
Q24671965 | Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation |
Q34335413 | Regulation and function of the peg3 imprinted domain |
Q60960055 | Regulation of Chromatin Structure During Neural Development |
Q24337687 | Regulation of E2F1 function by the nuclear corepressor KAP1 |
Q28659478 | Regulation of Mouse Retroelement MuERV-L/MERVL Expression by REX1 and Epigenetic Control of Stem Cell Potency |
Q28585312 | Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex |
Q33707691 | Relationship between histone H3 lysine 9 methylation, transcription repression, and heterochromatin protein 1 recruitment. |
Q35260579 | Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch |
Q48771662 | Remodeling of heterochromatin structure slows neuropathological progression and prolongs survival in an animal model of Huntington's disease. |
Q28067125 | Repair of DNA Double-Strand Breaks in Heterochromatin |
Q39057569 | Replication stress and chromatin context link ATM activation to a role in DNA replication. |
Q39713121 | Repression of IP-10 by interactions between histone deacetylation and hypermethylation in idiopathic pulmonary fibrosis |
Q36215800 | Reprogramming cell fate with a genome-scale library of artificial transcription factors. |
Q40066661 | Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression |
Q39110529 | Role of Histone Lysine Methyltransferases SUV39H1 and SETDB1 in Gliomagenesis: Modulation of Cell Proliferation, Migration, and Colony Formation |
Q38787077 | Role of genome guardian proteins in transcriptional elongation. |
Q37769114 | Role of histone methylation and demethylation in adipogenesis and obesity. |
Q36639797 | Role of several histone lysine methyltransferases in tumor development |
Q37961784 | Roles of RNAi in Chromatin Regulation and Epigenetic Inheritance |
Q37615671 | SET for life: biochemical activities and biological functions of SET domain-containing proteins |
Q34427470 | SET8 recognizes the sequence RHRK20VLRDN within the N terminus of histone H4 and mono-methylates lysine 20. |
Q92570251 | SETDB-1: A Potential Epigenetic Regulator in Breast Cancer Metastasis |
Q58596731 | SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice |
Q35097426 | SETDB1 accelerates tumourigenesis by regulating the WNT signalling pathway |
Q37024818 | SETDB1 mediated FosB expression increases the cell proliferation rate during anticancer drug therapy |
Q90317043 | SETDB1 mediated histone H3 lysine 9 methylation suppresses MLL-fusion target expression and leukemic transformation |
Q36032490 | SETDB1 modulates PRC2 activity at developmental genes independently of H3K9 trimethylation in mouse ES cells |
Q92676703 | SETDB1 modulates the differentiation of both the crystal cells and the lamellocytes in Drosophila |
Q94562316 | SETDB1 promotes the progression of colorectal cancer via epigenetically silencing p21 expression |
Q64085932 | SETDB1 regulates SMAD7 expression for breast cancer metastasis |
Q35709996 | SETDB1, HP1 and SUV39 promote repositioning of 53BP1 to extend resection during homologous recombination in G2 cells. |
Q91259720 | SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis |
Q64063071 | SMARCAD1 ATPase activity is required to silence endogenous retroviruses in embryonic stem cells |
Q33785287 | SMARCAD1 Contributes to the Regulation of Naive Pluripotency by Interacting with Histone Citrullination |
Q33854004 | SPR-5 and MET-2 function cooperatively to reestablish an epigenetic ground state during passage through the germ line |
Q36997854 | SUMO wrestling with Ras. |
Q39962765 | SUMO-modified Sp3 represses transcription by provoking local heterochromatic gene silencing |
Q24307960 | SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1 |
Q50287033 | SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) |
Q34174809 | Self-interaction of heterochromatin protein 1 is required for direct binding to histone methyltransferase, SUV39H1. |
Q37426752 | SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state |
Q30495175 | Setdb1 histone methyltransferase regulates mood-related behaviors and expression of the NMDA receptor subunit NR2B. |
Q34464546 | Setdb1 is required for myogenic differentiation of C2C12 myoblast cells via maintenance of MyoD expression |
Q34511024 | Setdb1-mediated histone H3K9 hypermethylation in neurons worsens the neurological phenotype of Mecp2-deficient mice |
Q34368215 | Should I stay or should I go: protection and maintenance of DNA methylation at imprinted genes. |
Q37252690 | Signal transducer and activator of transcription 3 limits Epstein-Barr virus lytic activation in B lymphocytes. |
Q26775416 | Signal transducer and activator of transcription 3 regulation by novel binding partners |
Q37827337 | Silencing chromatin: comparing modes and mechanisms |
Q39119025 | Silencing of endogenous retroviruses by heterochromatin |
Q47831063 | Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia. |
Q36926242 | Silencing of the Il2 gene transcription is regulated by epigenetic changes in anergic T cells |
Q34107315 | Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9. |
Q55002950 | Silencing of transposable elements may not be a major driver of regulatory evolution in primate iPSCs. |
Q35964130 | Sin3: a flexible regulator of global gene expression and genome stability. |
Q38552741 | Sound of silence: the properties and functions of repressive Lys methyltransferases. |
Q40081931 | Spatial distribution of histone methylation during MHC class II expression |
Q26782206 | Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family |
Q34531990 | Step out of the groove: epigenetic gene control systems and engineered transcription factors |
Q24646957 | Structural basis for the product specificity of histone lysine methyltransferases |
Q27643095 | Structural basis of HP1/PXVXL motif peptide interactions and HP1 localisation to heterochromatin |
Q37829702 | Structure and Function of Histone H3 Lysine 9 Methyltransferases and Demethylases |
Q27639757 | Structure and catalytic mechanism of a SET domain protein methyltransferase |
Q24646827 | Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase |
Q34126327 | Substitutions in the Amino-Terminal Tail of Neurospora Histone H3 Have Varied Effects on DNA Methylation |
Q40504274 | Substrate specificity and kinetic mechanism of mammalian G9a histone H3 methyltransferase |
Q38116514 | Sumoylation at the Host-Pathogen Interface |
Q40171341 | Sumoylation of the transcriptional intermediary factor 1beta (TIF1beta), the Co-repressor of the KRAB Multifinger proteins, is required for its transcriptional activity and is modulated by the KRAB domain |
Q36478099 | Suppression and recovery of BRCA1-mediated transcription by HP1γ via modulation of promoter occupancy |
Q98945200 | Synthetic immunomodulation with a CRISPR super-repressor in vivo |
Q47252056 | Systematic genetic interaction studies identify histone demethylase Utx as potential target for ameliorating Huntington's disease |
Q79374289 | TEL/ETV6 binds to corepressor KAP1 via the HLH domain |
Q28581440 | TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77 |
Q28590323 | TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids |
Q43123488 | TRIM28 Controls Genomic Imprinting through Distinct Mechanisms during and after Early Genome-wide Reprogramming |
Q26796250 | TRIM28 as a novel transcriptional elongation factor |
Q38827071 | TRIM28 as an independent prognostic marker plays critical roles in glioma progression |
Q91166006 | TRIM28 down-regulation on methylation imprints in bovine preimplantation embryos |
Q48025310 | TRIM28 is an Epigenetic Barrier to Induced Pluripotent Stem Cell Reprogramming |
Q37349418 | TRIM28 is essential for erythroblast differentiation in the mouse |
Q28513391 | TRIM28 is required by the mouse KRAB domain protein ZFP568 to control convergent extension and morphogenesis of extra-embryonic tissues |
Q36471255 | TRIM28 mediates chromatin modifications at the TCRα enhancer and regulates the development of T and natural killer T cells |
Q36841416 | TRIM28 mediates primer binding site-targeted silencing of Lys1,2 tRNA-utilizing retroviruses in embryonic cells |
Q54312343 | TRIM28 prevents autoinflammatory T cell development in vivo |
Q39067871 | TRIM28 represses transcription of endogenous retroviruses in neural progenitor cells. |
Q36660136 | TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells |
Q49268679 | TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency |
Q38742837 | TRIMming p53's anticancer activity |
Q38170892 | TRIMmunity: the roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity |
Q90707206 | Targeting DNA repair in cancer: current state and novel approaches |
Q39175486 | Targeting histone methylation for colorectal cancer |
Q37384129 | Telomeres, histone code, and DNA damage response |
Q89638553 | The "ART" of Epigenetics in Melanoma: From histone "Alterations, to Resistance and Therapies" |
Q36972711 | The ATM Substrate KAP1 Controls DNA Repair in Heterochromatin: Regulation by HP1 Proteins and Serine 473/824 Phosphorylation |
Q39026954 | The B-subdomain of the Xenopus laevis XFIN KRAB-AB domain is responsible for its weaker transcriptional repressor activity compared to human ZNF10/Kox1. |
Q37117525 | The B-type lamin is required for somatic repression of testis-specific gene clusters |
Q47068972 | The C. elegans HP1 homologue HPL-2 and the LIN-13 zinc finger protein form a complex implicated in vulval development |
Q36350569 | The Dynamics and Regulatory Mechanism of Pronuclear H3k9me2 Asymmetry in Mouse Zygotes |
Q92715615 | The Emerging Role of H3K9me3 as a Potential Therapeutic Target in Acute Myeloid Leukemia |
Q24558692 | The Epstein-Barr virus replication protein BBLF2/3 provides an origin-tethering function through interaction with the zinc finger DNA binding protein ZBRK1 and the KAP-1 corepressor |
Q37631226 | The Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals |
Q57295438 | The H3K9 methyltransferase SETDB1 maintains female identity in Drosophila germ cells |
Q24317426 | The HP1alpha-CAF1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin |
Q34618586 | The Immediate Early Gene Product EGR1 and Polycomb Group Proteins Interact in Epigenetic Programming during Chondrogenesis |
Q24672128 | The KAP1 corepressor functions to coordinate the assembly of de novo HP1-demarcated microenvironments of heterochromatin required for KRAB zinc finger protein-mediated transcriptional repression |
Q42519231 | The KRAB domain zinc finger protein, Zfp157, is expressed in multiple tissues during mouse embryogenesis and in specific cells in adult mammary gland and skin |
Q37546071 | The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis |
Q28512405 | The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration |
Q33247592 | The KRAB-associated co-repressor KAP-1 is a coiled-coil binding partner, substrate and activator of the c-Fes protein tyrosine kinase |
Q92205124 | The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons |
Q39801387 | The Kruppel-like zinc finger protein ZNF224 recruits the arginine methyltransferase PRMT5 on the transcriptional repressor complex of the aldolase A gene |
Q36127086 | The Krüppel-associated box repressor domain can induce reversible heterochromatization of a mouse locus in vivo. |
Q35089043 | The Krüppel-associated box repressor domain induces reversible and irreversible regulation of endogenous mouse genes by mediating different chromatin states |
Q33631545 | The Obesity-Linked Gene Nudt3 Drosophila Homolog Aps Is Associated With Insulin Signaling |
Q37680327 | The PR-Set7 binding domain of Riz1 is required for the H4K20me1-H3K9me1 trans-tail 'histone code' and Riz1 tumor suppressor function |
Q33933099 | The RNA helicase Rm62 cooperates with SU(VAR)3-9 to re-silence active transcription in Drosophila melanogaster |
Q47765950 | The Role of KRAB-ZFPs in Transposable Element Repression and Mammalian Evolution |
Q37937460 | The Roles of the Methyl-CpG Binding Proteins in Cancer |
Q73513751 | The SCAN domain defines a large family of zinc finger transcription factors |
Q24811144 | The SET-domain protein superfamily: protein lysine methyltransferases |
Q37581605 | The TIF1β-HP1 system maintains transcriptional integrity of hematopoietic stem cells |
Q36141179 | The Transcriptional Repressive Activity of KRAB Zinc Finger Proteins Does Not Correlate with Their Ability to Recruit TRIM28. |
Q24595581 | The accessible chromatin landscape of the human genome |
Q33546685 | The ancient mammalian KRAB zinc finger gene cluster on human chromosome 8q24.3 illustrates principles of C2H2 zinc finger evolution associated with unique expression profiles in human tissues. |
Q37832719 | The changing faces of HP1: From heterochromatin formation and gene silencing to euchromatic gene expression: HP1 acts as a positive regulator of transcription |
Q28183858 | The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome |
Q36408543 | The contradictory definitions of heterochromatin: transcription and silencing. |
Q37958430 | The control of HIV transcription: keeping RNA polymerase II on track |
Q90196318 | The control of gene expression and cell identity by H3K9 trimethylation |
Q46263609 | The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity |
Q92883018 | The epigenetic regulator ATF7ip inhibits Il2 expression, regulating Th17 responses |
Q28068278 | The epigenome: the next substrate for engineering |
Q33235274 | The evolution of the histone methyltransferase gene Su(var)3-9 in metazoans includes a fusion with and a re-fission from a functionally unrelated gene |
Q38992195 | The evolutionary capacitor HSP90 buffers the regulatory effects of mammalian endogenous retroviruses. |
Q34283901 | The genetic basis of non-syndromic intellectual disability: a review |
Q36250669 | The histone methyltransferase DOT1L: regulatory functions and a cancer therapy target |
Q24336175 | The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells |
Q92558804 | The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification |
Q52319773 | The long non-coding RNA Paupar promotes KAP1-dependent chromatin changes and regulates olfactory bulb neurogenesis |
Q35113394 | The methyl-CpG binding domain and the evolving role of DNA methylation in animals |
Q45062538 | The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. |
Q36319982 | The mouse genome displays highly dynamic populations of KRAB-zinc finger protein genes and related genetic units |
Q42813673 | The novel Nrf2-interacting factor KAP1 regulates susceptibility to oxidative stress by promoting the Nrf2-mediated cytoprotective response |
Q35640798 | The preRC protein ORCA organizes heterochromatin by assembling histone H3 lysine 9 methyltransferases on chromatin |
Q41462037 | The proteomic investigation of chromatin functional domains reveals novel synergisms among distinct heterochromatin components |
Q24306374 | The structurally disordered KRAB repression domain is incorporated into a protease resistant core upon binding to KAP-1-RBCC domain |
Q96222254 | The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer |
Q34531694 | The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36. |
Q40149571 | The transcriptional repressor K-RBP modulates RTA-mediated transactivation and lytic replication of Kaposi's sarcoma-associated herpesvirus |
Q41906267 | The zinc finger DNA-binding domain of K-RBP plays an important role in regulating Kaposi's sarcoma-associated herpesvirus RTA-mediated gene expression |
Q40215892 | The zinc finger transcription factor 191 is required for early embryonic development and cell proliferation |
Q38128684 | Towards an understanding of the regulatory mechanisms of totipotency |
Q34179511 | Transcription and RNA interference in the formation of heterochromatin. |
Q34181413 | Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma |
Q42155239 | Transcription factor effector domains |
Q33707631 | Transcription factor interactions and chromatin modifications associated with p53-mediated, developmental repression of the alpha-fetoprotein gene |
Q38043829 | Transcription-associated histone modifications and cryptic transcription |
Q37512799 | Transcriptional Silencing of Moloney Murine Leukemia Virus in Human Embryonic Carcinoma Cells |
Q37429465 | Transcriptional control of brown adipocyte development and physiological function--of mice and men. |
Q34531622 | Transcriptional regulators TRIM28, SETDB1, and TP53 are aberrantly expressed in porcine embryos produced by in vitro fertilization in comparison to in vivo- and somatic-cell nuclear transfer-derived embryos |
Q90484418 | Transient DNMT3L Expression Reinforces Chromatin Surveillance to Halt Senescence Progression in Mouse Embryonic Fibroblast |
Q28709521 | Transposable Elements Re-Wire and Fine-Tune the Transcriptome |
Q57026544 | Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8 |
Q35199282 | Trim28 contributes to EMT via regulation of E-cadherin and N-cadherin in lung cancer cell lines |
Q41970615 | Trimethylation of histone H3 lysine 4 impairs methylation of histone H3 lysine 9: regulation of lysine methyltransferases by physical interaction with their substrates. |
Q36418751 | Tripartite Motif Containing 28 (Trim28) Can Regulate Cell Proliferation by Bridging HDAC1/E2F Interactions |
Q47069021 | Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development |
Q38736774 | URI Regulates KAP1 Phosphorylation and Transcriptional Repression via PP2A Phosphatase in Prostate Cancer Cells |
Q52723071 | USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization |
Q28109675 | Ubiquitination of Lysine 867 of the Human SETDB1 Protein Upregulates Its Histone H3 Lysine 9 (H3K9) Methyltransferase Activity |
Q40654465 | Unique DNA methylome profiles in CpG island methylator phenotype colon cancers |
Q89842501 | Unphosphorylated STAT3 in heterochromatin formation and tumor suppression in lung cancer |
Q53306403 | Up-regulation of histone methyltransferase SETDB1 by multiple mechanisms in hepatocellular carcinoma promotes cancer metastasis. |
Q33502742 | Windei, the Drosophila homolog of mAM/MCAF1, is an essential cofactor of the H3K9 methyl transferase dSETDB1/Eggless in germ line development |
Q34476349 | Writing and rewriting the epigenetic code of cancer cells: from engineered proteins to small molecules |
Q36663018 | X-linked mental retardation and epigenetics |
Q98192782 | ZCWPW1 is recruited to recombination hotspots by PRDM9, and is essential for meiotic double strand break repair |
Q38871585 | ZFP57 and the Targeted Maintenance of Postfertilization Genomic Imprints. |
Q41147495 | ZNF10 inhibits HIV-1 LTR activity through interaction with NF-κB and Sp1 binding motifs |
Q24318366 | ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes |
Q35499791 | ZNF300 knockdown inhibits forced megakaryocytic differentiation by phorbol and erythrocytic differentiation by arabinofuranosyl cytidine in K562 cells |
Q34398844 | ZNF674: a new kruppel-associated box-containing zinc-finger gene involved in nonsyndromic X-linked mental retardation |
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Q42367973 | dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression. |
Q33336609 | dSETDB1 and SU(VAR)3-9 sequentially function during germline-stem cell differentiation in Drosophila melanogaster |
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Q89863683 | ncHMR detector: a computational framework to systematically reveal non-classical functions of histone modification regulators |
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