| scholarly article | Q13442814 |
| P50 | author | Pier Paolo Pandolfi | Q7191735 |
| John M Asara | Q56936246 | ||
| Jian Zhang | Q68692588 | ||
| Wenyi Wei | Q68692593 | ||
| Wenjian Gan | Q89518739 | ||
| P2093 | author name string | Min Yuan | |
| Yang Shi | |||
| Jianping Guo | |||
| Xiangpeng Dai | |||
| Pengda Liu | |||
| Alex Toker | |||
| Ailan Guo | |||
| Nana Zheng | |||
| Benoit Laurent | |||
| P2860 | cites work | p53 is regulated by the lysine demethylase LSD1 | Q24292925 |
| Methylation of the retinoblastoma tumor suppressor by SMYD2 | Q24300912 | ||
| The E3 ligase TRAF6 regulates Akt ubiquitination and activation | Q24310343 | ||
| Regulation of p53 activity through lysine methylation | Q24311514 | ||
| Akt/PKB interacts with the histone H3 methyltransferase SETDB1 and coordinates to silence gene expression | Q24312056 | ||
| Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases | Q24315937 | ||
| The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells | Q24336175 | ||
| Modulation of p53 function by SET8-mediated methylation at lysine 382 | Q24337822 | ||
| The PI3K-PDK1 connection: more than just a road to PKB | Q24531972 | ||
| Multiplex genome engineering using CRISPR/Cas systems | Q24609428 | ||
| The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis | Q24613186 | ||
| The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset | Q24625220 | ||
| SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins | Q24685694 | ||
| A transforming mutation in the pleckstrin homology domain of AKT1 in cancer | Q27646556 | ||
| Potent inhibition of DOT1L as treatment of MLL-fusion leukemia | Q27678800 | ||
| The phosphoinositide 3-kinase pathway | Q27860738 | ||
| Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice | Q43726502 | ||
| Histone methyltransferase SETDB1 maintains survival of mouse spermatogonial stem/progenitor cells via PTEN/AKT/FOXO1 pathway. | Q47825900 | ||
| Up-regulation of histone methyltransferase SETDB1 by multiple mechanisms in hepatocellular carcinoma promotes cancer metastasis. | Q53306403 | ||
| HDAC inhibitors: clinical update and mechanism-based potential | Q53333442 | ||
| SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis | Q91259720 | ||
| Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B | Q28116107 | ||
| NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase | Q28144326 | ||
| BET bromodomain inhibition as a therapeutic strategy to target c-Myc | Q28247024 | ||
| The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data | Q28266682 | ||
| Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3 | Q28276951 | ||
| Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate | Q28301966 | ||
| Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene | Q28349476 | ||
| Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha | Q28616168 | ||
| Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3 | Q28943520 | ||
| Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma | Q29614282 | ||
| Exploiting the PI3K/AKT pathway for cancer drug discovery | Q29615120 | ||
| ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease | Q30478632 | ||
| Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase | Q30490786 | ||
| Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53 | Q33663060 | ||
| Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus | Q33826685 | ||
| A semisynthetic epitope for kinase substrates. | Q34100971 | ||
| Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells | Q34235670 | ||
| Cancer Genetics and Epigenetics: Two Sides of the Same Coin? | Q34287662 | ||
| SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer | Q34420873 | ||
| Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development | Q34699020 | ||
| SETDB1 accelerates tumourigenesis by regulating the WNT signalling pathway | Q35097426 | ||
| Targeting the PI3K-Akt pathway in human cancer: rationale and promise | Q35571372 | ||
| A murine model for the development of melanocytic nevi and their progression to melanoma | Q36073207 | ||
| MC1R is a potent regulator of PTEN after UV exposure in melanocytes | Q37220171 | ||
| Epigenetic Activation of AP1 Promotes Squamous Cell Carcinoma Metastasis | Q37632913 | ||
| pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner | Q37666827 | ||
| Epigenetic modifications as therapeutic targets | Q37800011 | ||
| DNA methyltransferase inhibitors in cancer: a chemical and therapeutic patent overview and selected clinical studies | Q38049175 | ||
| Non-histone protein methylation as a regulator of cellular signalling and function | Q38285792 | ||
| Targeting the cancer epigenome for therapy | Q38821103 | ||
| Triomics Analysis of Imatinib-Treated Myeloma Cells Connects Kinase Inhibition to RNA Processing and Decreased Lipid Biosynthesis. | Q38830422 | ||
| Immunoaffinity enrichment and mass spectrometry analysis of protein methylation | Q39078089 | ||
| AKT/PKB Signaling: Navigating the Network | Q39255027 | ||
| Braf(V600E) cooperates with Pten loss to induce metastatic melanoma | Q39873596 | ||
| Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue. | Q40968963 | ||
| Mechanisms and consequences of activation of protein kinase B/Akt | Q41751003 | ||
| SMYD3-mediated lysine methylation in the PH domain is critical for activation of AKT1. | Q42317470 | ||
| P433 | issue | 2 | |
| P304 | page(s) | 226-237 | |
| P577 | publication date | 2019-01-28 | |
| P1433 | published in | Nature Cell Biology | Q1574111 |
| P1476 | title | AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions | |
| P478 | volume | 21 |
| Q93018670 | A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1 |
| Q98906856 | Aberrant JmjC domain-containing protein 8 (JMJD8) expression promotes activation of AKT and tumor epithelial-mesenchymal transition |
| Q64113810 | Emerging roles of H3K9me3, SETDB1 and SETDB2 in therapy-induced cellular reprogramming |
| Q90080042 | Epigenetic Regulation of p21cip1/waf1 in Human Cancer |
| Q90430690 | Essential roles of Windei and nuclear monoubiquitination of Eggless/SETDB1 in transposon silencing |
| Q91728282 | Fine-tuning AKT kinase activity through direct lysine methylation |
| Q92715652 | LSD1 Activates PI3K/AKT Signaling Through Regulating p85 Expression in Prostate Cancer Cells |
| Q99708097 | Long noncoding RNA PTCSC1 drives esophageal squamous cell carcinoma progression through activating Akt signaling |
| Q97424529 | Mithramycin A and Mithralog EC-8042 Inhibit SETDB1 Expression and Its Oncogenic Activity in Malignant Melanoma |
| Q91259716 | Oncogenic AKTivation by methylation |
| Q93108977 | Phosphoinositide spatially free AKT/PKB activation to all membrane compartments |
| Q92570251 | SETDB-1: A Potential Epigenetic Regulator in Breast Cancer Metastasis |
| Q94562316 | SETDB1 promotes the progression of colorectal cancer via epigenetically silencing p21 expression |
| Q91259720 | SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis |
| Q100385811 | The cross-talk between methylation and phosphorylation in lymphoid-specific helicase drives cancer stem-like properties |
| Q90093670 | The role of ubiquitination in tumorigenesis and targeted drug discovery |
| Q96230063 | WSTF acetylation by MOF promotes WSTF activities and oncogenic functions |
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