A cohesin/HUSH- and LINC-dependent pathway controls ribosomal DNA double-strand break repair

scientific article published on 08 August 2019

A cohesin/HUSH- and LINC-dependent pathway controls ribosomal DNA double-strand break repair is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1101/GAD.324012.119
P932PMC publication ID6719620
P698PubMed publication ID31395742

P50authorPhilippe MangeotQ64681190
Aline MarnefQ81819728
Emiliano P RicciQ42428098
P2093author name stringGaëlle Legube
Virginie Daburon
Thomas Mangeat
Vincent Rocher
Emmanuelle Guillou
Anne-Laure Finoux
Coline Arnould
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Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair.Q30524137
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A role for nuclear envelope-bridging complexes in homology-directed repairQ34081445
Cohesin protects genes against γH2AX Induced by DNA double-strand breaksQ34140001
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A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage.Q35750783
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DNA damage induces nuclear actin filament assembly by Formin -2 and Spire-½ that promotes efficient DNA repair. [corrected].Q36080669
DNA double strand break repair pathway choice: a chromatin based decision?Q36191863
Heterochromatic breaks move to the nuclear periphery to continue recombinational repair.Q36235927
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MST2 kinase suppresses rDNA transcription in response to DNA damage by phosphorylating nucleolar histone H2B.Q54107827
Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks.Q55088632
The HUSH complex cooperates with TRIM28 to repress young retrotransposons and new genes.Q55204321
Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair.Q55426834
Comprehensive Mapping of Histone Modifications at DNA Double-Strand Breaks Deciphers Repair Pathway Chromatin SignaturesQ57071316
CRISPR–Cas9 genome editing in human cells occurs via the Fanconi anemia pathwayQ58054240
Nuclear ARP2/3 drives DNA break clustering for homology-directed repairQ59066262
Nuclear F-actin and myosins drive relocalization of heterochromatic breaksQ59066270
Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteinsQ60921859
Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome InstabilityQ61446989
Keep moving and stay in a good shape to find your homologous recombination partnerQ64389080
Double-strand breaks in ribosomal RNA genes activate a distinct signaling and chromatin response to facilitate nucleolar restructuring and repairQ92655486
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The cohesin complex prevents the end-joining of distant DNA double-strand ends in S phase: Consequences on genome stability maintenanceQ37289739
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The Cohesin Complex Prevents the End Joining of Distant DNA Double-Strand Ends.Q38810243
ATM Dependent Silencing Links Nucleolar Chromatin Reorganization to DNA Damage RecognitionQ38829976
Transcription-Coupled DNA Double-Strand Break Repair: Active Genes Need Special Care.Q38864090
Transcriptional elongation factor ENL phosphorylated by ATM recruits polycomb and switches off transcription for DSB repairQ38881302
Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatinQ38971238
Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks.Q39012832
Endogenous DNA Damage as a Source of Genomic Instability in CancerQ39130435
High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome.Q39719766
53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repairQ39750906
GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells.Q41529408
Microtubule dynamics drive enhanced chromatin motion and mobilize telomeres in response to DNA damage.Q41827167
KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response.Q42152404
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Inefficient double-strand break repair in murine rod photoreceptors with inverted heterochromatin organization.Q50665513
Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution.Q52653703
Dynamic regulation of nucleolar architecture.Q52660466
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A meeting at risk: Unrepaired DSBs go for broke.Q52746256
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SWR1 and INO80 chromatin remodelers contribute to DNA double-strand break perinuclear anchorage site choice.Q53031445
P433issue17-18
P304page(s)1175-1190
P577publication date2019-08-08
P1433published inGenes & DevelopmentQ1524533
P1476titleA cohesin/HUSH- and LINC-dependent pathway controls ribosomal DNA double-strand break repair
P478volume33

Reverse relations

cites work (P2860)
Q101166878Genome-wide detection of DNA double-strand breaks by in-suspension BLISS
Q101216854The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s
Q101409898The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal