A DNA repair protein and histone methyltransferase interact to promote genome stability in the Caenorhabditis elegans germ line

scientific article published on 22 February 2019

A DNA repair protein and histone methyltransferase interact to promote genome stability in the Caenorhabditis elegans germ line is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1007992
P932PMC publication ID6402707
P698PubMed publication ID30794539

P50authorJudith L YanowitzQ57334369
Eleanor M MaineQ91118679
Xia XuQ91831285
P2093author name stringBing Yang
Logan Russell
Matthew T Sullenberger
P2860cites workHARP is an ATP-driven annealing helicaseQ24310525
The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restartQ24319812
The genetics of Caenorhabditis elegansQ24533408
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteinsQ24685694
Linking replication stress with heterochromatin formationQ26778138
C. elegans Heterochromatin Factor SET-32 Plays an Essential Role in Transgenerational Establishment of Nuclear RNAi-Mediated Epigenetic SilencingQ93274049
Differential RPA-1 and RAD-51 recruitment in vivo throughout the C. elegans germline, as revealed by laser microirradiationQ47290516
Dependency of Heterochromatin Domains on Replication Factors.Q47350699
Histone H3K9 methylation is dispensable for Caenorhabditis elegans development but suppresses RNA:DNA hybrid-associated repeat instability.Q50278958
The RNAi Inheritance Machinery of Caenorhabditis elegans.Q50987178
Schimke immuno-osseous dysplasia: SMARCAL1 loss-of-function and phenotypic correlation.Q52693780
GSK-3 promotes S phase entry and progression in C. elegans germline stem cells to maintain tissue output.Q52716637
Chromatin conformation regulates the coordination between DNA replication and transcription.Q52717242
SMARCAL1 deficiency predisposes to non-Hodgkin lymphoma and hypersensitivity to genotoxic agents in vivo.Q55436386
Regulated nuclear accumulation of a histone methyltransferase times the onset of heterochromatin formation in embryosQ58722669
A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cellsQ59348999
DNA repairQ80124303
Chromatin Modifiers SET-25 and SET-32 Are Required for Establishment but Not Long-Term Maintenance of Transgenerational Epigenetic InheritanceQ93274045
Caenorhabditis elegans histone methyltransferase MET-2 shields the male X chromosome from checkpoint machinery and mediates meiotic sex chromosome inactivationQ27336177
mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repressionQ28208422
Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assemblyQ28278522
Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsisQ28279936
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE projectQ28301622
hnRNP K coordinates transcriptional silencing by SETDB1 in embryonic stem cellsQ28543055
The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosisQ28611306
Meiotic recombination, noncoding DNA and genomic organization in Caenorhabditis elegansQ28769447
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assemblyQ29614718
Meiotic pairing and imprinted X chromatin assembly in Caenorhabditis elegansQ30411914
X-chromosome silencing in the germline of C. elegansQ30412367
RAD-51-dependent and -independent roles of a Caenorhabditis elegans BRCA2-related protein during DNA double-strand break repairQ30780655
Poly-G/poly-C tracts in the genomes of CaenorhabditisQ33305160
Windei, the Drosophila homolog of mAM/MCAF1, is an essential cofactor of the H3K9 methyl transferase dSETDB1/Eggless in germ line developmentQ33502742
The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forksQ33507753
Identification of SMARCAL1 as a component of the DNA damage responseQ33511423
Differential localization and independent acquisition of the H3K9me2 and H3K9me3 chromatin modifications in the Caenorhabditis elegans adult germ lineQ33526991
A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stressQ33574854
Coordinated control of terminal differentiation and restriction of cellular plasticityQ33580677
DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatinQ33834990
EGO-1, a putative RNA-dependent RNA polymerase, is required for heterochromatin assembly on unpaired dna during C. elegans meiosisQ33903495
Random and targeted transgene insertion in Caenorhabditis elegans using a modified Mos1 transposonQ34018995
Mutant chromatin remodeling protein SMARCAL1 causes Schimke immuno-osseous dysplasia.Q34110155
DNA replication, RNAi and epigenetic inheritanceQ34243575
Chromatin replication and epigenome maintenanceQ34256428
Characterization of monoclonal antibody to DNA.RNA and its application to immunodetection of hybridsQ34384604
Efficient marker-free recovery of custom genetic modifications with CRISPR/Cas9 in Caenorhabditis elegansQ34471658
A conserved checkpoint monitors meiotic chromosome synapsis in Caenorhabditis elegansQ34474546
Comparative analysis of metazoan chromatin organizationQ34486035
A Caenorhabditis elegans tissue model of radiation-induced reproductive cell deathQ34540371
Broad chromosomal domains of histone modification patterns in C. elegansQ34548272
Scalable and versatile genome editing using linear DNAs with microhomology to Cas9 Sites in Caenorhabditis elegansQ34636173
Substrate-selective repair and restart of replication forks by DNA translocasesQ34762664
Homologous recombination is required for genome stability in the absence of DOG-1 in Caenorhabditis elegansQ34895210
Nuclear reorganization and homologous chromosome pairing during meiotic prophase require C. elegans chk-2.Q35079512
High-affinity DNA-binding domains of replication protein A (RPA) direct SMARCAL1-dependent replication fork remodelingQ35080276
Mutator phenotype of Caenorhabditis elegans DNA damage checkpoint mutantsQ35083072
The annealing helicase and branch migration activities of Drosophila HARP.Q35174890
Linking DNA replication to heterochromatin silencing and epigenetic inheritanceQ35629825
Smarcal1 promotes double-strand-break repair by nonhomologous end-joining.Q35668100
SETDB1, HP1 and SUV39 promote repositioning of 53BP1 to extend resection during homologous recombination in G2 cells.Q35709996
SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replicationQ35740608
Histone chaperone Anp32e removes H2A.Z from DNA double-strand breaks and promotes nucleosome reorganization and DNA repairQ35764396
Enrichment of H3K9me2 on Unsynapsed Chromatin in Caenorhabditis elegans Does Not Target de Novo SitesQ36012704
emo-1, a Caenorhabditis elegans Sec61p gamma homologue, is required for oocyte development and ovulationQ36237200
Annealing of Complementary DNA Sequences During Double-Strand Break Repair in Drosophila Is Mediated by the Ortholog of SMARCAL1.Q36297096
Systematic identification of factors for provirus silencing in embryonic stem cellsQ36390458
DOG-1 is the Caenorhabditis elegans BRIP1/FANCJ homologue and functions in interstrand cross-link repairQ36483479
Homologous recombination as a mechanism to recognize repetitive DNA sequences in an RNAi pathwayQ36592389
Soma-germ cell interactions in Caenorhabditis elegans: multiple events of hermaphrodite germline development require the somatic sheath and spermathecal lineagesQ36844317
Promotion of Homologous Recombination by SWS-1 in Complex with RAD-51 Paralogs in Caenorhabditis elegans.Q36875574
Mitochondrial Stress Induces Chromatin Reorganization to Promote Longevity and UPR(mt).Q36956834
Chromatin structure and the inheritance of epigenetic informationQ37141498
Germline survival and apoptosisQ37264487
Novel insights into RAD51 activity and regulation during homologous recombination and DNA replicationQ37302669
SMARCAL1 Resolves Replication Stress at ALT Telomeres.Q37312254
Meiotic recombination and the crossover assurance checkpoint in Caenorhabditis elegansQ37371435
Methods for studying the DNA damage response in the Caenorhabdatis elegans germ lineQ37973926
Meiosis.Q38676330
SMARCAL1 and telomeres: Replicating the troublesome endsQ38880488
ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH ComplexQ39298989
The role of SMARCAL1 in replication fork stability and telomere maintenanceQ39379179
Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.Q39737989
Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD.Q39749476
Replication stress affects the fidelity of nucleosome-mediated epigenetic inheritance.Q41324231
Impaired DNA replication derepresses chromatin and generates a transgenerationally inherited epigenetic memoryQ41434826
And yet, it moves: nuclear and chromatin dynamics of a heterochromatic double-strand break.Q41568442
Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA.Q44052691
Step-wise methylation of histone H3K9 positions heterochromatin at the nuclear periphery.Q47068818
Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval developmentQ47069021
CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegansQ47069350
Genetic and cytological characterization of the recombination protein RAD-51 in Caenorhabditis elegansQ47069371
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectCaenorhabditis elegansQ91703
genome stabilityQ98655700
P304page(s)e1007992
P577publication date2019-02-22
P1433published inPLOS GeneticsQ1893441
P1476titleA DNA repair protein and histone methyltransferase interact to promote genome stability in the Caenorhabditis elegans germ line
P478volume15

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cites work (P2860)
Q98507748Caenorhabditis elegans nuclear RNAi factor SET-32 deposits the transgenerational histone modification, H3K23me3
Q90196326Distinct functions and temporal regulation of methylated histone H3 during early embryogenesis
Q90193835The Epigenetics of Aging in Invertebrates

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