scholarly article | Q13442814 |
P356 | DOI | 10.1038/NG.3672 |
P2888 | exact match | https://scigraph.springernature.com/pub.10.1038/ng.3672 |
P698 | PubMed publication ID | 27668659 |
P50 | author | Susan M. Gasser | Q21062334 |
Peter Zeller | Q57342975 | ||
Marcel Tijsterman | Q59431291 | ||
P2093 | author name string | Robin van Schendel | |
Jan Padeken | |||
Veronique Kalck | |||
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Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster | Q24556518 | ||
Fast and accurate short read alignment with Burrows-Wheeler transform | Q24653853 | ||
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis | Q24673923 | ||
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The Caenorhabditis elegans THO complex is required for the mitotic cell cycle and development | Q27324679 | ||
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Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells | Q28253382 | ||
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Histone H3-K9 methyltransferase ESET is essential for early development | Q28513000 | ||
The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis | Q28611306 | ||
Repbase Update, a database of eukaryotic repetitive elements | Q29547460 | ||
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly | Q29614718 | ||
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Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability | Q29620365 | ||
S1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation. | Q30368627 | ||
Epigenetic regulation of cholinergic receptor M1 (CHRM1) by histone H3K9me3 impairs Ca(2+) signaling in Huntington's disease | Q30539113 | ||
Transcriptional profiling in C. elegans suggests DNA damage dependent apoptosis as an ancient function of the p53 family | Q33351781 | ||
H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stability | Q33641829 | ||
Mechanisms of genome instability induced by RNA-processing defects | Q33691010 | ||
Mobile elements and the human genome | Q33938490 | ||
Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline | Q34012402 | ||
Requirement of heterochromatin for cohesion at centromeres | Q34094956 | ||
Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells | Q34235670 | ||
Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes | Q34242723 | ||
RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability | Q34242729 | ||
R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters | Q34258378 | ||
The distribution of repressive histone modifications on silenced FMR1 alleles provides clues to the mechanism of gene silencing in fragile X syndrome | Q34275676 | ||
Position effect variegation at fission yeast centromeres. | Q34348065 | ||
R loops are linked to histone H3 S10 phosphorylation and chromatin condensation | Q34383922 | ||
Characterization of monoclonal antibody to DNA.RNA and its application to immunodetection of hybrids | Q34384604 | ||
Genome-wide distribution of RNA-DNA hybrids identifies RNase H targets in tRNA genes, retrotransposons and mitochondria | Q34427946 | ||
Bidirectional transcription stimulates expansion and contraction of expanded (CTG)*(CAG) repeats. | Q34470663 | ||
Broad chromosomal domains of histone modification patterns in C. elegans | Q34548272 | ||
Caenorhabditis elegans chromosome arms are anchored to the nuclear membrane via discontinuous association with LEM-2 | Q34613778 | ||
An AT-rich sequence in human common fragile site FRA16D causes fork stalling and chromosome breakage in S. cerevisiae | Q34659849 | ||
The H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes peritoneal metastasis. | Q34662610 | ||
Repetitive DNA sequences located in the terminal portion of the Caenorhabditis elegans chromosomes | Q34975181 | ||
Mutator phenotype of Caenorhabditis elegans DNA damage checkpoint mutants | Q35083072 | ||
Break-seq reveals hydroxyurea-induced chromosome fragility as a result of unscheduled conflict between DNA replication and transcription | Q35157225 | ||
R-loop-mediated genomic instability is caused by impairment of replication fork progression | Q35393287 | ||
Transcription as a source of genome instability | Q36036444 | ||
Differential regulation of DNA damage response activation between somatic and germline cells in Caenorhabditis elegans. | Q36311155 | ||
PRG-1 and 21U-RNAs interact to form the piRNA complex required for fertility in C. elegans | Q36943578 | ||
De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes | Q36968883 | ||
Methods for studying the DNA damage response in the Caenorhabdatis elegans germ line | Q37973926 | ||
Causes of genome instability | Q38126068 | ||
Co-directional replication-transcription conflicts lead to replication restart | Q38337096 | ||
Repeat DNA in genome organization and stability. | Q38445548 | ||
The regulation and functions of the nuclear RNA exosome complex. | Q38685674 | ||
Gossypol and an HMT G9a inhibitor act in synergy to induce cell death in pancreatic cancer cells. | Q39134027 | ||
H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM. | Q39645130 | ||
Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD. | Q39749476 | ||
Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi | Q39895156 | ||
Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells. | Q39986966 | ||
The spatial dynamics of tissue-specific promoters during C. elegans development | Q40014678 | ||
The organization of histone H3 modifications as revealed by a panel of specific monoclonal antibodies | Q40129996 | ||
Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae | Q41843323 | ||
QuasR: quantification and annotation of short reads in R. | Q43213442 | ||
Centromere silencing and function in fission yeast is governed by the amino terminus of histone H3. | Q44619061 | ||
Step-wise methylation of histone H3K9 positions heterochromatin at the nuclear periphery. | Q47068818 | ||
Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development | Q47069021 | ||
A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegans | Q47069275 | ||
CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans | Q47069350 | ||
Activation of a transposable element in the germ line but not the soma of Caenorhabditis elegans. | Q52255509 | ||
Transposon silencing in the Caenorhabditis elegans germ line by natural RNAi | Q59093938 | ||
Repetitive Transgenes in C. elegans Accumulate Heterochromatic Marks and Are Sequestered at the Nuclear Envelope in a Copy-Number- and Lamin-Dependent Manner | Q61275222 | ||
Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence | Q63977008 | ||
DNA replication fork pause sites dependent on transcription | Q71096003 | ||
HYDROXYUREA: A SPECIFIC INHIBITOR OF DEOXYRIBONUCLEIC ACID SYNTHESIS | Q78346078 | ||
A combined chemical and genetic approach for the generation of induced pluripotent stem cells | Q81393717 | ||
Comprehensive analysis of heterochromatin- and RNAi-mediated epigenetic control of the fission yeast genome | Q81886031 | ||
New lysine methyltransferase drug targets in cancer | Q84560534 | ||
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Caenorhabditis elegans | Q91703 |
P304 | page(s) | 1385-1395 | |
P577 | publication date | 2016-09-26 | |
P1433 | published in | Nature Genetics | Q976454 |
P1476 | title | Histone H3K9 methylation is dispensable for Caenorhabditis elegans development but suppresses RNA:DNA hybrid-associated repeat instability. | |
P478 | volume | 48 |
Q64114668 | A DNA repair protein and histone methyltransferase interact to promote genome stability in the Caenorhabditis elegans germ line |
Q52724144 | A conserved function for pericentromeric satellite DNA. |
Q33574854 | A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress |
Q92154314 | Advances in epigenetics link genetics to the environment and disease |
Q48147622 | Broad Chromatin Domains: An Important Facet of Genome Regulation. |
Q100750303 | CDCA7 and HELLS suppress DNA:RNA hybrid-associated DNA damage at pericentromeric repeats |
Q33580677 | Coordinated control of terminal differentiation and restriction of cellular plasticity |
Q37727855 | Cross-Regulation between Transposable Elements and Host DNA Replication |
Q51360124 | Dangerous R loops form in the absence of H3K9 methylation. |
Q37644161 | Decoupling the downstream effects of germline nuclear RNAi reveals that H3K9me3 is dispensable for heritable RNAi and the maintenance of endogenous siRNA-mediated transcriptional silencing in Caenorhabditis elegans |
Q52718765 | Deletion of HP1γ in cardiac myocytes affects H4K20me3 levels but does not impact cardiac growth. |
Q64099428 | Destabilization of chromosome structure by histone H3 lysine 27 methylation |
Q90196326 | Distinct functions and temporal regulation of methylated histone H3 during early embryogenesis |
Q52431111 | Entering the post-epigenomic age: back to epigenetics. |
Q48135038 | Epigenetic mechanisms in health and disease: BCEC 2017. |
Q47352829 | Functional Redundancy of Variant and Canonical Histone H3 Lysine 9 Modification in Drosophila |
Q89966219 | H3K9 Demethylation-Induced R-Loop Accumulation Is Linked to Disorganized Nucleoli |
Q92203183 | HOT or not: examining the basis of high-occupancy target regions |
Q60911595 | Heterochromatin suppresses gross chromosomal rearrangements at centromeres by repressing Tfs1/TFIIS-dependent transcription |
Q60207541 | Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer. |
Q52680682 | JMJD-1.2 controls multiple histone post-translational modifications in germ cells and protects the genome from replication stress. |
Q91595909 | LSM2-8 and XRN-2 contribute to the silencing of H3K27me3-marked genes through targeted RNA decay |
Q41448600 | Linker histone H1 prevents R-loop accumulation and genome instability in heterochromatin |
Q46543801 | MORC-1 Integrates Nuclear RNAi and Transgenerational Chromatin Architecture to Promote Germline Immortality |
Q52321974 | Mechanisms of Oncogene-Induced Replication Stress: Jigsaw Falling into Place. |
Q41565087 | Nucleolar expansion and elevated protein translation in premature aging |
Q93132994 | PHF2 histone demethylase prevents DNA damage and genome instability by controlling cell cycle progression of neural progenitors |
Q92351733 | Paradoxical association of TET loss of function with genome-wide DNA hypomethylation |
Q52627910 | Perturbed autophagy and DNA repair converge to promote neurodegeneration in amyotrophic lateral sclerosis and dementia. |
Q91208639 | R Loops and Their Composite Cancer Connections |
Q45054633 | RNA-DNA hybrid (R-loop) immunoprecipitation mapping: an analytical workflow to evaluate inherent biases. |
Q47107044 | Regulation of mitotic recombination between DNA repeats in centromeres. |
Q64055118 | Repression of Germline Genes in Somatic Tissues by H3K9 Dimethylation of Their Promoters |
Q48148054 | Repressive Chromatin in Caenorhabditis elegans: Establishment, Composition, and Function |
Q52579677 | Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers. |
Q50789005 | SNF2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance and Proper Replication. |
Q42741284 | Selfish DNA and Epigenetic Repression Revisited. |
Q47831063 | Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia. |
Q89518731 | Small-RNA-mediated transgenerational silencing of histone genes impairs fertility in piRNA mutants |
Q98184288 | Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration |
Q64092144 | Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression |
Q60916829 | Systematic evaluation of C. elegans lincRNAs with CRISPR knockout mutants |
Q46162198 | Ten principles of heterochromatin formation and function. |
Q41373535 | The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription. |
Q39400453 | The Role of Replication-Associated Repair Factors on R-Loops |
Q49666338 | The double-stranded RNA binding protein RDE-4 can act cell autonomously during feeding RNAi in C. elegans. |
Q64108584 | The meiotic phosphatase GSP-2/PP1 promotes germline immortality and small RNA-mediated genome silencing |
Q52607336 | Transgenerational Sterility of Piwi Mutants Represents a Dynamic Form of Adult Reproductive Diapause. |
Q90167250 | Visualization and Quantification of Transposon Activity in Caenorhabditis elegans RNAi Pathway Mutants |
Q89763818 | Widespread loss of the silencing epigenetic mark H3K9me3 in astrocytes and neurons along with hippocampal-dependent cognitive impairment in C9orf72 BAC transgenic mice |
Q92542211 | Yeast Sirtuin Family Members Maintain Transcription Homeostasis to Ensure Genome Stability |
Q89588350 | miR24-2 accelerates progression of liver cancer cells by activating Pim1 through tri-methylation of Histone H3 on the ninth lysine |
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