Sound of silence: the properties and functions of repressive Lys methyltransferases.

scientific article published on July 2015

Sound of silence: the properties and functions of repressive Lys methyltransferases. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1009881946
P356DOI10.1038/NRM4029
P698PubMed publication ID26204160

P50authorChiara MozzettaQ57306807
Yekaterina BoyarchukQ79810593
P2093author name stringSlimane Ait-Si-Ali
Julien Pontis
P2860cites workGenomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domainsQ21092474
Molecular architecture of human polycomb repressive complex 2Q21128799
Regulation of chromatin structure by site-specific histone H3 methyltransferasesQ24290115
Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4Q24294553
JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cellsQ24295145
A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cellsQ24297079
Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repressionQ24300386
Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activityQ24301878
Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiationQ24304060
Histone H3 lysine 56 methylation regulates DNA replication through its interaction with PCNAQ24306661
An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targetingQ24307370
CLLD8/KMT1F is a lysine methyltransferase that is important for chromosome segregationQ24307396
Specificity of the chromodomain Y chromosome family of chromodomains for lysine-methylated ARK(S/T) motifsQ24308689
Epigenetic control of rDNA loci in response to intracellular energy statusQ24313528
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 ProteinsQ24316425
The HP1alpha-CAF1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatinQ24317426
ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genesQ24318366
Histone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1Q24320777
Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivatorsQ24336164
The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cellsQ24336175
Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expressionQ24515238
An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors mSin3A/BQ24535295
A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cellsQ24535932
Structure-function analysis of SUV39H1 reveals a dominant role in heterochromatin organization, chromosome segregation, and mitotic progressionQ24554215
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatinQ24561636
Genome-wide maps of chromatin state in pluripotent and lineage-committed cellsQ24632506
In vitro and in vivo analyses of a Phe/Tyr switch controlling product specificity of histone lysine methyltransferasesQ24645737
EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotencyQ24645960
Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomesQ24671073
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAsQ24673619
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesisQ24673923
Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replicationQ24675218
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteinsQ24685694
A chromosomal memory triggered by Xist regulates histone methylation in X inactivationQ24802695
Protein methylation at the surface and buried deep: thinking outside the histone boxQ27025874
Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferaseQ27640679
The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modulesQ27649828
Role of the polycomb protein EED in the propagation of repressive histone marksQ27657483
Histone methylation by PRC2 is inhibited by active chromatin marksQ27667743
SET domain proteins modulate chromatin domains in eu- and heterochromatin.Q34458687
PTMs on H3 variants before chromatin assembly potentiate their final epigenetic stateQ34575324
Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeresQ34604352
The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation.Q34624060
Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A.Q34691326
AGO2 and SETDB1 cooperate in promoter-targeted transcriptional silencing of the androgen receptor geneQ34712114
Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencingQ34804800
AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2.Q34964097
Specificity, propagation, and memory of pericentric heterochromatinQ34986658
CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing.Q34998982
Recognition of H3K9 methylation by GLP is required for efficient establishment of H3K9 methylation, rapid target gene repression, and mouse viabilityQ35104153
The zinc finger proteins ZNF644 and WIZ regulate the G9a/GLP complex for gene repressionQ35194348
Functional Crosstalk Between Lysine Methyltransferases on Histone Substrates: The Case of G9A/GLP and Polycomb Repressive Complex 2Q35609473
Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A RegulatorQ35692081
Lysine methyltransferase G9a methylates the transcription factor MyoD and regulates skeletal muscle differentiationQ35735009
The transcriptional and epigenomic foundations of ground state pluripotency.Q36100410
AS1DHRS4, a head-to-head natural antisense transcript, silences the DHRS4 gene cluster in cis and transQ36212913
Asymmetrically modified nucleosomesQ36401114
Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5AQ36414731
G9a mediates Sharp-1-dependent inhibition of skeletal muscle differentiationQ36465083
KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands.Q36474376
The control of histone lysine methylation in epigenetic regulationQ36571342
H2A.Z facilitates access of active and repressive complexes to chromatin in embryonic stem cell self-renewal and differentiation.Q36604868
Ezh1 and Ezh2 maintain repressive chromatin through different mechanismsQ36810306
PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse.Q36851813
Chromatin connections to pluripotency and cellular reprogrammingQ36874359
Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCsQ36927892
De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET.Q36966957
De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genesQ36968883
Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly.Q37118383
Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse developmentQ37145387
Modulation of lysine methylation in myocyte enhancer factor 2 during skeletal muscle cell differentiation.Q37417041
SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell stateQ37426752
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteinsQ27860456
High-resolution profiling of histone methylations in the human genomeQ27860906
A bivalent chromatin structure marks key developmental genes in embryonic stem cellsQ27860977
Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatinQ28187783
SUV39H1 interacts with AML1 and abrogates AML1 transactivity. AML1 is methylated in vivoQ28201653
mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repressionQ28208422
Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3Q28214048
Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factorQ28215563
Control of developmental regulators by Polycomb in human embryonic stem cellsQ28235841
A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodellingQ28242453
Histone methylation: a dynamic mark in health, disease and inheritanceQ28263573
Domain organization of human chromosomes revealed by mapping of nuclear lamina interactionsQ28279406
Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2Q28280326
A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouseQ28289637
Histone H1 and its isoforms: contribution to chromatin structure and functionQ28303037
Physical and functional association of SU(VAR)3-9 and HDAC1 in DrosophilaQ28360331
The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structureQ28473586
Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cellsQ28506827
The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatinQ28506981
The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiationQ28508225
Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cellsQ28585926
HP1 binds specifically to Lys26-methylated histone H1.4, whereas simultaneous Ser27 phosphorylation blocks HP1 bindingQ28587228
Histone methyltransferase Suv39h1 represses MyoD-stimulated myogenic differentiationQ28588561
An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitmentQ28593101
NSD1 is essential for early post-implantation development and has a catalytically active SET domainQ28593118
Prdm16 is required for the maintenance of brown adipocyte identity and function in adult miceQ28593617
Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9Q28594945
Histone methyltransferases direct different degrees of methylation to define distinct chromatin domainsQ28609779
PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatinQ28647369
Distinct roles of KAP1, HP1 and G9a/GLP in silencing of the two-cell-specific retrotransposon MERVL in mouse ES cellsQ28681397
Polycomb complexes repress developmental regulators in murine embryonic stem cellsQ29547274
The Polycomb complex PRC2 and its mark in lifeQ29547358
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosomeQ29547359
Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulationQ29614333
Partitioning and plasticity of repressive histone methylation states in mammalian chromatinQ29614513
Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation statesQ46567995
Step-wise methylation of histone H3K9 positions heterochromatin at the nuclear periphery.Q47068818
The chromo and SET domains of the Clr4 protein are essential for silencing in fission yeastQ47991804
Gene silencing triggers polycomb repressive complex 2 recruitment to CpG islands genome wide.Q50650644
Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases.Q51598430
Structural differences in centromeric heterochromatin are spatially reconciled on fertilisation in the mouse zygote.Q51756263
Polycomb protein Ezh1 promotes RNA polymerase II elongation.Q51832730
Silencing of endogenous retroviruses: when and why do histone marks predominate?Q51834987
Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors.Q51956004
RUNX1 associates with histone deacetylases and SUV39H1 to repress transcription.Q52570374
The SENP7 SUMO-Protease Presents a Module of Two HP1 Interaction Motifs that Locks HP1 Protein at Pericentric Heterochromatin.Q52969109
SUMOylation promotes de novo targeting of HP1α to pericentric heterochromatinQ57549485
A transcription factor–based mechanism for mouse heterochromatin formationQ64387285
Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammalsQ84042482
Multivalent engagement of chromatin modifications by linked binding modulesQ29617236
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stabilityQ29620365
Rb targets histone H3 methylation and HP1 to promotersQ29620452
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferaseQ33272939
Family expansion and gene rearrangements contributed to the functional specialization of PRDM genes in vertebrates.Q33301582
The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrateQ33553524
Active and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome.Q33760054
GC-rich sequence elements recruit PRC2 in mammalian ES cellsQ33775517
The central role of EED in the orchestration of polycomb group complexes.Q33815083
Distinct epigenomic landscapes of pluripotent and lineage-committed human cells.Q33842527
DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation.Q34017960
Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitmentQ34022860
The histone H3 lysine 9 methyltransferases G9a and GLP regulate polycomb repressive complex 2-mediated gene silencingQ34039506
The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.Q34043853
Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation.Q34128674
The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells.Q34144213
TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration.Q34181742
Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cellsQ34235670
The MSX1 homeoprotein recruits G9a methyltransferase to repressed target genes in myoblast cellsQ34282108
An epigenetic silencing pathway controlling T helper 2 cell lineage commitmentQ34286068
EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex.Q34382953
Polycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelityQ34388755
Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferaseQ34445102
Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cellsQ37426774
G9a selectively represses a class of late-replicating genes at the nuclear periphery.Q37428891
Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiationQ37449132
A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assemblyQ37533718
ESET methylates UBF at K232/254 and regulates nucleolar heterochromatin plasticity and rDNA transcription.Q37574135
Histone H3 lysine 4 (H3K4) methylation in development and differentiationQ37585674
SET for life: biochemical activities and biological functions of SET domain-containing proteinsQ37615671
A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausingQ37635773
Understanding the language of Lys36 methylation at histone H3.Q37672319
Decoding the histone H4 lysine 20 methylation markQ37782080
The diverse functions of Dot1 and H3K79 methylation.Q37897061
Polycomb group proteins: repression in 3D.Q37906862
The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesisQ38015891
The Prdm family: expanding roles in stem cells and developmentQ38016394
Emerging roles for chromatin as a signal integration and storage platformQ38092575
Transcriptional regulation by Polycomb group proteinsQ38149730
Histone lysine demethylases as targets for anticancer therapyQ38162717
Polycomb silencing: from linear chromatin domains to 3D chromosome foldingQ38179206
R-loops induce repressive chromatin marks over mammalian gene terminatorsQ38949719
Single-cell dynamics of genome-nuclear lamina interactionsQ39176932
Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20.Q39291348
Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitinationQ39703639
Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.Q39737989
Ezh2 requires PHF1 to efficiently catalyze H3 lysine 27 trimethylation in vivo.Q40011376
Methylation of a histone mimic within the histone methyltransferase G9a regulates protein complex assemblyQ40091979
Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation.Q40406465
Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1.Q40694593
PR-Set7-dependent methylation of histone H4 Lys 20 functions in repression of gene expression and is essential for mitosisQ41078460
The Msx1 Homeoprotein Recruits Polycomb to the Nuclear Periphery during DevelopmentQ41578287
Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cellsQ41868578
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cellsQ41960997
Trimethylation of histone H3 lysine 4 impairs methylation of histone H3 lysine 9: regulation of lysine methyltransferases by physical interaction with their substrates.Q41970615
H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosomeQ42076431
Suv39h-dependent H3K9me3 marks intact retrotransposons and silences LINE elements in mouse embryonic stem cells.Q42209064
Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiationQ42472280
Quiescence-induced LncRNAs trigger H4K20 trimethylation and transcriptional silencingQ42803505
G9a co-suppresses LINE1 elements in spermatogonia.Q42918668
Histone methyltransferase G9a contributes to H3K27 methylation in vivoQ42939574
A subset of the histone H3 lysine 9 methyltransferases Suv39h1, G9a, GLP, and SETDB1 participate in a multimeric complex.Q43175284
Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotencyQ43194593
Reassessing the abundance of H3K9me2 chromatin domains in embryonic stem cellsQ43206621
Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.Q45262911
FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methyltransferase and impairs myogenesis.Q45290619
Argonaute proteins couple chromatin silencing to alternative splicing.Q45345567
P433issue8
P304page(s)499-513
P577publication date2015-08-01
P1433published inNature Reviews Molecular Cell BiologyQ1573120
P1476titleSound of silence: the properties and functions of repressive Lys methyltransferases
P478volume16

Reverse relations

cites work (P2860)
Q36283537A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin
Q38738529A cross-talk between DNA methylation and H3 lysine 9 dimethylation at the KvDMR1 region controls the induction of Cdkn1c in muscle cells.
Q39096411A drive in SUVs: From development to disease
Q60908127ANKHD1 is required for SMYD3 to promote tumor metastasis in hepatocellular carcinoma
Q90430696ATF7IP regulates SETDB1 nuclear localization and increases its ubiquitination
Q39298989ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex
Q47157361Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes.
Q36956991Anaplasma phagocytophilum increases the levels of histone modifying enzymes to inhibit cell apoptosis and facilitate pathogen infection in the tick vector Ixodes scapularis.
Q64111220Antigen receptor control of methionine metabolism in T cells
Q42172387Application of dual reading domains as novel reagents in chromatin biology reveals a new H3K9me3 and H3K36me2/3 bivalent chromatin state.
Q38803790Association of ORCA/LRWD1 with repressive histone methyl transferases mediates heterochromatin organization
Q91651372Cockayne syndrome group B deficiency reduces H3K9me3 chromatin remodeler SETDB1 and exacerbates cellular aging
Q46288028Computational characterization of substrate and product specificities, and functionality of S-adenosylmethionine binding pocket in histone lysine methyltransferases from Arabidopsis, rice and maize
Q54116646Contrasting epigenetic states of heterochromatin in the different types of mouse pluripotent stem cells.
Q60922662DOT1L inhibition blocks multiple myeloma cell proliferation by suppressing IRF4-MYC signaling
Q48298211Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase.
Q92410964Epigenetic Regulation of Chromatin in Prostate Cancer
Q33764436Epigenetic regulation of epithelial-mesenchymal transition
Q90430690Essential roles of Windei and nuclear monoubiquitination of Eggless/SETDB1 in transposon silencing
Q42158675Establishment of expression-state boundaries by Rif1 and Taz1 in fission yeast
Q92528246Expression of the Major and Pro-Oncogenic H3K9 Lysine Methyltransferase SETDB1 in Non-Small Cell Lung Cancer
Q58745588G9a Correlates with VLA-4 Integrin and Influences the Migration of Childhood Acute Lymphoblastic Leukemia Cells
Q37126598Generalized nucleation and looping model for epigenetic memory of histone modifications
Q47139599H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Q64070328Histone 4 Lysine 20 Methylation: A Case for Neurodevelopmental Disease
Q50072349How Communication Between Nucleosomes Enables Spreading and Epigenetic Memory of Histone Modifications
Q64092199Identification of human silencers by correlating cross-tissue epigenetic profiles and gene expression
Q26775369Insights into epigenetic landscape of recombination-free regions
Q39768084Investigation of H2AX methylation by the SUV39H2 protein lysine methyltransferase
Q90610454KDM2A/B lysine demethylases and their alternative isoforms in development and disease
Q64252282KDM4B: A Nail for Every Hammer?
Q64101984KMT1 family methyltransferases regulate heterochromatin-nuclear periphery tethering via histone and non-histone protein methylation
Q57799763LncRNA HOTAIR regulates lipopolysaccharide-induced cytokine expression and inflammatory response in macrophages
Q90013973Lung Cancer Therapy Targeting Histone Methylation: Opportunities and Challenges
Q64101463Lysine methylation of transcription factors in cancer
Q27309192Mechanisms underlying epigenetic and transcriptional heterogeneity in Chinese hamster ovary (CHO) cell lines
Q88669970Metabolic regulation of chromatin modifications and gene expression
Q39440781Orchestration of H3K27 methylation: mechanisms and therapeutic implication
Q38725574Position-effect variegation revisited: HUSHing up heterochromatin in human cells.
Q38861640Protein and Genetic Composition of Four Chromatin Types in Drosophila melanogaster Cell Lines
Q39212312Protein arginine methylation: a prominent modification and its demethylation
Q52095907Regulation of USP37 Expression by REST-Associated G9a-Dependent Histone Methylation.
Q41863682Relating protein functional diversity to cell type number identifies genes that determine dynamic aspects of chromatin organisation as potential contributors to organismal complexity.
Q31157515Retrieving Chromatin Patterns from Deep Sequencing Data Using Correlation Functions.
Q58596731SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice
Q36115303SETDB2 Links Glucocorticoid to Lipid Metabolism through Insig2a Regulation
Q52871562SIRT6: a new guardian of mitosis.
Q55002950Silencing of transposable elements may not be a major driver of regulatory evolution in primate iPSCs.
Q64107073Somatic Embryogenesis Induction in Woody Species: The Future After OMICs Data Assessment
Q36648714Suppression of F1 Male-Specific Lethality in Caenorhabditis Hybrids by cbr-him-8.
Q59357685Switching roles for DNA and histone methylation depend on evolutionary ages of human endogenous retroviruses
Q64092144Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression
Q64961640TSPYL2 Regulates the Expression of EZH2 Target Genes in Neurons.
Q96304809The Emerging Roles of Heterochromatin in Cell Migration
Q90311780The H3K9 Methylation Writer SETDB1 and its Reader MPP8 Cooperate to Silence Satellite DNA Repeats in Mouse Embryonic Stem Cells
Q59793161The Heterochromatin Landscape in Migrating Cells and the Importance of H3K27me3 for Associated Transcriptome Alterations
Q58718492The biological significance of histone modifiers in multiple myeloma: clinical applications
Q92376610The roles of homologous recombination and the immune system in the genomic evolution of cancer
Q97544686Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction
Q57026544Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8

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