The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.

scientific article

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3. is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1026152883
P356DOI10.1038/NATURE14443
P932PMC publication ID4516396
P698PubMed publication ID25915022
P5875ResearchGate publication ID275525480

P50authorEric LanderQ970550
Mitchell GuttmanQ59667368
Kathrin PlathQ30347917
P2093author name stringAnnie Moradian
Colleen A McHugh
Amy Chow
Michael J Sweredoski
Sonja Hess
Patrick McDonel
Alexander A Shishkin
Christina Tran
Mario Blanco
Chun-Kan Chen
Amy Pandya-Jones
Christina Burghard
Christine F Surka
Julia Su
P2860cites workATRX directs binding of PRC2 to Xist RNA and Polycomb targetsQ24307468
YY1 tethers Xist RNA to the inactive X nucleation centerQ24311256
HITS-CLIP: panoramic views of protein-RNA regulation in living cellsQ24594553
Sharp, an inducible cofactor that integrates nuclear receptor repression and activationQ24601805
A conserved structural motif reveals the essential transcriptional repression function of Spen proteins and their role in developmental signalingQ24671921
A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silencedQ24672840
[Cl-]i-dependent phosphorylation of the Na-K-Cl cotransport protein of dog tracheal epithelial cells.Q41267502
Nucleic-acid-binding properties of hnRNP-U/SAF-A, a nuclear-matrix protein which binds DNA and RNA in vivo and in vitroQ41412940
Effect of mass spectrometric parameters on peptide and protein identification rates for shotgun proteomic experiments on an LTQ-orbitrap mass analyzerQ44145999
Gene silencing triggers polycomb repressive complex 2 recruitment to CpG islands genome wide.Q50650644
Use of stable isotope labeling by amino acids in cell culture as a spike-in standard in quantitative proteomicsQ83366737
The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA recognition motifsQ27683484
Genome regulation by long noncoding RNAs.Q27691812
Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylationQ28139187
Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genesQ28255974
Roles of histone acetyltransferases and deacetylases in gene regulationQ28286019
A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC)Q28296386
Identification of a sequence-specific single-stranded DNA binding protein that suppresses transcription of the mouse myelin basic protein geneQ28592062
Pfam: the protein families databaseQ28660698
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantificationQ29547200
The Polycomb complex PRC2 and its mark in lifeQ29547358
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosomeQ29547359
lincRNAs act in the circuitry controlling pluripotency and differentiationQ29614325
Role of histone H3 lysine 27 methylation in X inactivationQ29614508
Andromeda: a peptide search engine integrated into the MaxQuant environmentQ29615816
Promiscuous RNA binding by Polycomb repressive complex 2.Q30457030
The Polycomb group protein EED is dispensable for the initiation of random X-chromosome inactivationQ30814417
Methods for comprehensive experimental identification of RNA-protein interactionsQ33745576
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosomeQ34037436
Target-decoy search strategy for mass spectrometry-based proteomicsQ34070061
Chromosomal silencing and localization are mediated by different domains of Xist RNA.Q34108304
RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sitesQ34253195
Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencingQ34767759
Specific targeting and constitutive association of histone deacetylase complexes during transcriptional repressionQ35005873
The A-repeat links ASF/SF2-dependent Xist RNA processing with random choice during X inactivationQ35108825
Ott1(Rbm15) has pleiotropic roles in hematopoietic developmentQ35749623
Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivoQ36589100
Automated analysis of FISH and immunohistochemistry images: a review.Q36845070
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activationQ37030330
Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenomeQ37302890
SATB1 defines the developmental context for gene silencing by Xist in lymphoma and embryonic cellsQ37719468
Lamin B receptor: multi-tasking at the nuclear envelopeQ37843677
Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formationQ37902049
The matrix protein hnRNP U is required for chromosomal localization of Xist RNA.Q40036180
X-Inactivation and histone H4 acetylation in embryonic stem cellsQ41145161
Evidence that heteronuclear proteins interact with XIST RNA in vitro.Q41169359
P433issue7551
P407language of work or nameEnglishQ1860
P304page(s)232-236
P577publication date2015-04-27
P1433published inNatureQ180445
P1476titleThe Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.
P478volume521

Reverse relations

cites work (P2860)
Q39453727'Lnc'-ing Wnt in female reproductive cancers: therapeutic potential of long non-coding RNAs in Wnt signalling.
Q34485792A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing
Q50334595A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets.
Q104502017A direct RNA-protein interaction atlas of the SARS-CoV-2 RNA in infected human cells
Q28066790A lncRNA Perspective into (Re)Building the Heart
Q39872709A long noncoding RNA associated with susceptibility to celiac disease
Q36958995A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes.
Q99248814A protein assembly mediates Xist localization and gene silencing
Q52594384A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors.
Q38290509A versatile tandem RNA isolation procedure to capture in vivo formed mRNA-protein complexes
Q26738495Advances in the characterization of RNA-binding proteins
Q49018891Age-Related Expression of a Repeat-Rich Intergenic Long Noncoding RNA in the Rat Brain
Q50549381All-Trans Retinoic Acid Induces Expression of a Novel Intergenic Long Noncoding RNA in Adult rat Primary Hippocampal Neurons
Q50002288Alteration of Epigenetic Regulation by Long Noncoding RNAs in Cancer
Q64076900Altered X-chromosome inactivation in T cells may promote sex-biased autoimmune diseases
Q91329332Alternative splicing coupled with transcript degradation modulates OAS1g antiviral activity
Q58766615An Oligonucleotide-based Tandem RNA Isolation Procedure to Recover Eukaryotic mRNA-Protein Complexes
Q38773163An RNA matchmaker protein regulates the activity of the long noncoding RNA HOTAIR
Q36192946An Xist-activating antisense RNA required for X-chromosome inactivation.
Q33884515An autonomous metabolic role for Spen
Q102379334An integrative atlas of chicken long non-coding genes and their annotations across 25 tissues
Q47598348An interferon-independent lncRNA promotes viral replication by modulating cellular metabolism
Q92719740Approaches for measuring the dynamics of RNA-protein interactions
Q92565163Artificial escape from XCI by DNA methylation editing of the CDKL5 gene
Q91029340BUD13 Promotes a Type I Interferon Response by Countering Intron Retention in Irf7
Q64904190Beyond CLIP: advances and opportunities to measure RBP-RNA and RNA-RNA interactions.
Q60961286Beyond Transcription: Fine-Tuning of Circadian Timekeeping by Post-Transcriptional Regulation
Q37231014Biochemical Methods To Investigate lncRNA and the Influence of lncRNA:Protein Complexes on Chromatin
Q39027949Biogenesis and Transcriptional Regulation of Long Noncoding RNAs in the Human Immune System.
Q35964734Bipartite structure of the inactive mouse X chromosome
Q33910575C. elegans SUP-46, an HNRNPM family RNA-binding protein that prevents paternally-mediated epigenetic sterility
Q48813459CANT1 lncRNA Triggers Efficient Therapeutic Efficacy by Correcting Aberrant lncing Cascade in Malignant Uveal Melanoma.
Q51472052Capture Hybridization Analysis of DNA Targets.
Q90095862Capturing RNA-protein interaction via CRUIS
Q47416156Catching RNAs on chromatin using hybridization capture methods.
Q45949886Cell Cycle Control by Nuclear Sequestration of CDC20 and CDH1 mRNA in Plant Stem Cells.
Q91713084Cellular functions of long noncoding RNAs
Q92125260Challenges and perspectives for structural biology of lncRNAs-the example of the Xist lncRNA A-repeats
Q38896956Challenges in the analysis of long noncoding RNA functionality.
Q36224826Characterization of Histone Modifications Associated with Inactive X-Chromosome in Trophoblast Stem Cells, eXtra-Embryonic Endoderm Cells and in In Vitro Derived Undifferentiated and Differentiated Epiblast Like Stem Cells
Q64230306Characterization of lncRNA-miRNA-mRNA Network to Reveal Potential Functional ceRNAs in Bovine Skeletal Muscle
Q28821825Chemical Tools for Dissecting the Role of lncRNAs in Epigenetic Regulation
Q92503341Chromatin-associated RNAs as facilitators of functional genomic interactions
Q36599564Cis- and trans-regulation in X inactivation
Q38723304Comment on "Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing".
Q90345514Comparison of Long Non-Coding RNA Expression Profiles of Cattle and Buffalo Differing in Muscle Characteristics
Q62516501Comprehensive identification of RNA–protein interactions in any organism using orthogonal organic phase separation (OOPS)
Q91807464Comprehensive in vivo identification of the c-Myc mRNA protein interactome using HyPR-MS
Q50053910Control of Immune Cell Homeostasis and Function by lncRNAs.
Q92784867Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation
Q36642197Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.
Q38656230Cytokines and Long Noncoding RNAs
Q98513733Decapping enzyme 1A breaks X-chromosome symmetry by controlling Tsix elongation and RNA turnover
Q54975879Deciphering the roles of lncRNAs in breast development and disease.
Q47784394Decreased expression of lncRNA VPS9D1-AS1 in gastric cancer and its clinical significance
Q92755609Decrypting noncoding RNA interactions, structures, and functional networks
Q88661256Desthiobiotin-Streptavidin-Affinity Mediated Purification of RNA-Interacting Proteins in Mesothelioma Cells
Q64910914Developmental Xist induction is mediated by enhanced splicing.
Q93372737Different effects of long noncoding RNA NDRG1-OT1 fragments on NDRG1 transcription in breast cancer cells under hypoxia
Q39014501Differential expression and emerging functions of non-coding RNAs in cold adaptation
Q64997790Directed Evolution of Split APEX2 Peroxidase.
Q38675323Divergent actions of long noncoding RNAs on X-chromosome remodelling in mammals and Drosophila achieve the same end result: dosage compensation.
Q91771278Diverging RNPs: Toward Understanding lncRNA-Protein Interactions and Functions
Q36936254Diverse regulatory interactions of long noncoding RNAs
Q92416869Down expression of lnc-BMP1-1 decreases that of Caveolin-1 is associated with the lung cancer susceptibility and cigarette smoking history
Q36447505Dynamic interplay and function of multiple noncoding genes governing X chromosome inactivation
Q57180652EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs
Q100311082Elements at the 5' end of Xist harbor SPEN-independent transcriptional antiterminator activity
Q47094347Elucidating the in vivo interactome of HIV-1 RNA by hybridization capture and mass spectrometry
Q33558692Embryonic loss of human females with partial trisomy 19 identifies region critical for the single active X.
Q47657395Emerging mechanisms of long noncoding RNA function during normal and malignant hematopoiesis
Q33601739Emerging role of long noncoding RNAs as regulators of innate immune cell development and inflammatory gene expression
Q37635533Emerging roles for long noncoding RNAs in skeletal biology and disease
Q38716433Emerging roles of non-coding RNAs in epigenetic regulation
Q34046402Enhancers as non-coding RNA transcription units: recent insights and future perspectives
Q41844368Enzymatic production of single-molecule FISH and RNA capture probes
Q47285280Epigenetic differences between naïve and primed pluripotent stem cells.
Q38889708Establishment of X chromosome inactivation and epigenomic features of the inactive X depend on cellular contexts
Q38644580Evolution and Biological Roles of Alternative 3'UTRs
Q48382417Exploring the dark matter of the human genome using oligonucleotide-based molecules
Q41178035Expression analysis of the Arabidopsis thaliana AtSpen2 gene, and its relationship with other plant genes encoding Spen proteins
Q47129510Extracellular Vesicle-Associated RNA as a Carrier of Epigenetic Information
Q38801253Finding function in mystery transcripts
Q26750257Function and evolution of the long noncoding RNA circuitry orchestrating X-chromosome inactivation in mammals
Q47102761Function by Structure: Spotlights on Xist Long Non-coding RNA.
Q49649796Functional Classification and Experimental Dissection of Long Noncoding RNAs
Q53789178Functional Dissection of the m6A RNA Modification.
Q89863711Functional Roles of Long Non-coding RNAs in Motor Neuron Development and Disease
Q91902372Functional diversity of small nucleolar RNAs
Q90403778Functions and properties of nuclear lncRNAs-from systematically mapping the interactomes of lncRNAs
Q37028376Functions of long noncoding RNAs in the nucleus
Q33737782Genome annotation for clinical genomic diagnostics: strengths and weaknesses
Q50035213Genome-wide differential expression profiling of mRNAs and lncRNAs associated with prolificacy in Hu sheep
Q30698865Grabbing the genome by the NADs
Q46317917HBL1 Is a Human Long Noncoding RNA that Modulates Cardiomyocyte Development from Pluripotent Stem Cells by Counteracting MIR1.
Q38603654HCV infection, IFN response and the coding and non-coding host cell genome
Q97530299HOTAIRM1 regulates neuronal differentiation by modulating NEUROGENIN 2 and the downstream neurogenic cascade
Q92212822HOXC-AS1-MYC regulatory loop contributes to the growth and metastasis in gastric cancer
Q37604320High Expression of LINC01420 indicates an unfavorable prognosis and modulates cell migration and invasion in nasopharyngeal carcinoma
Q42332214High-Resolution Mapping of RNA-Binding Regions in the Nuclear Proteome of Embryonic Stem Cells.
Q41678364How do lncRNAs regulate transcription?
Q89748394How to silence an X chromosome
Q89417778HyPR-MS for Multiplexed Discovery of MALAT1, NEAT1, and NORAD lncRNA Protein Interactomes
Q60910559Identification and analysis of long non-coding RNAs in response to H5N1 influenza viruses in duck (Anas platyrhynchos)
Q64087529Identification of Key lncRNAs Associated With Atherosclerosis Progression Based on Public Datasets
Q51472042Identification of RNA-Protein Interactions Through In Vitro RNA Pull-Down Assays.
Q47449956Identification of RNA-binding domains of RNA-binding proteins in cultured cells on a system-wide scale with RBDmap.
Q34485787Identification of Spen as a Crucial Factor for Xist Function through Forward Genetic Screening in Haploid Embryonic Stem Cells.
Q64263210Identification of a Xist silencing domain by Tiling CRISPR
Q90650432Identification of novel LncRNA targeting Smad2/PKCα signal pathway to negatively regulate malignant progression of glioblastoma
Q90133800Identification of proteins and miRNAs that specifically bind an mRNA in vivo
Q92378790Identifying lncRNA-mediated regulatory modules via ChIA-PET network analysis
Q39104939Immunobiology of Long Noncoding RNAs.
Q91404418In-cell identification and measurement of RNA-protein interactions
Q33709621Increased lncRNA ABHD11-AS1 represses the malignant phenotypes of bladder cancer
Q36447611Insight into lncRNA biology using hybridization capture analyses
Q40735479Insights into the activation mechanism of class I HDAC complexes by inositol phosphates
Q50420655Integration of lncRNA and mRNA Transcriptome Analyses Reveals Genes and Pathways Potentially Involved in Calf Intestinal Growth and Development during the Early Weeks of Life
Q36002405Integrative genomic analysis in K562 chronic myelogenous leukemia cells reveals that proximal NCOR1 binding positively regulates genes that govern erythroid differentiation and Imatinib sensitivity.
Q96640366Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2
Q52312154Interplay between long non-coding RNAs and epigenetic machinery: emerging targets in cancer?
Q92594989Kinetics of Xist-induced gene silencing can be predicted from combinations of epigenetic and genomic features
Q98184327LINC00941 promotes CRC metastasis through preventing SMAD4 protein degradation and activating the TGF-β/SMAD2/3 signaling pathway
Q36774942LINC01225 promotes occurrence and metastasis of hepatocellular carcinoma in an epidermal growth factor receptor-dependent pathway
Q41664396Lamin B Receptor: Interplay between Structure, Function and Localization.
Q64064616Lamina Associated Domains and Gene Regulation in Development and Cancer
Q45874846Landscape of DNA methylation on the marsupial X.
Q26782744Linking RNA biology to lncRNAs
Q58742709Live-Cell Imaging and Functional Dissection of Xist RNA Reveal Mechanisms of X Chromosome Inactivation and Reactivation
Q37486949LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells.
Q91495125LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis
Q36189779LncRNA BCAR4 wires up signaling transduction in breast cancer
Q37085883LncRNA MT1JP functions as a tumor suppressor by interacting with TIAR to modulate the p53 pathway
Q89555490LncRNA RUNX1-IT1 which is downregulated by hypoxia-driven histone deacetylase 3 represses proliferation and cancer stem-like properties in hepatocellular carcinoma cells
Q47214652LncRNA Structural Characteristics in Epigenetic Regulation
Q92618633LncRNA-SNHG3 is an independent prognostic biomarker of intrahepatic cholangiocarcinoma
Q37208291LncSox4 promotes the self-renewal of liver tumour-initiating cells through Stat3-mediated Sox4 expression.
Q57811092Local Tandem Repeat Expansion in RNA as a Model for the Functionalisation of ncRNA
Q91650129Localized accumulation of Xist RNA in X chromosome inactivation
Q92129207Long Non-Coding RNA Function in CD4+ T Cells: What We Know and What Next?
Q51058624Long Non-Coding RNA XIST Promotes Osteosarcoma Progression by Targeting Ras-Related Protein RAP2B via miR-320b.
Q53451121Long Noncoding RNA PVT1 Facilitates Cervical Cancer Progression via Negative Regulating of miR-424.
Q47258279Long Noncoding RNA in Cancer: Wiring Signaling Circuitry
Q37377215Long Noncoding RNA lncCAMTA1 Promotes Proliferation and Cancer Stem Cell-Like Properties of Liver Cancer by Inhibiting CAMTA1.
Q36796798Long Noncoding RNAs in Cancer Pathways
Q46319913Long Noncoding RNAs in Mammalian Development and Diseases
Q91835721Long non-coding RNA LUCAT1/miR-5582-3p/TCF7L2 axis regulates breast cancer stemness via Wnt/β-catenin pathway
Q99413656Long non-coding RNA SNHG12 promotes immune escape of ovarian cancer cells through their crosstalk with M2 macrophages
Q37706144Long non-coding RNA XIST promotes cell growth and invasion through regulating miR-497/MACC1 axis in gastric cancer
Q55019234Long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 promotes lung adenocarcinoma by directly interacting with specificity protein 1.
Q36604464Long non-coding RNA regulation of reproduction and development
Q38646918Long non-coding RNAs as an epigenetic regulator in human cancers
Q64922153Long non-coding RNAs in hematopoietic regulation.
Q90274816Long non-coding RNAs regulate drug resistance in cancer
Q38990786Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression
Q38782691Long noncoding RNA FGFR3-AS1 promotes osteosarcoma growth through regulating its natural antisense transcript FGFR3.
Q39630055Long noncoding RNA GIHCG promotes hepatocellular carcinoma progression through epigenetically regulating miR-200b/a/429.
Q38766067Long noncoding RNA PVT1 promotes cervical cancer progression through epigenetically silencing miR-200b
Q64235369Long noncoding RNA X-inactive specific transcript as a prognostic factor in cancer patients: A meta-analysis based on retrospective studies
Q47106149Long noncoding RNA XIST is a prognostic factor in colorectal cancer and inhibits 5-fluorouracil-induced cell cytotoxicity through promoting thymidylate synthase expression
Q47138459Long noncoding RNA XIST promotes malignancies of esophageal squamous cell carcinoma via regulation of miR-101/EZH2.
Q92002667Long noncoding RNAs and the regulation of innate immunity and host-virus interactions
Q38639536Long noncoding RNAs and tumorigenesis: genetic associations, molecular mechanisms, and therapeutic strategies
Q26742057Long noncoding RNAs in hematopoiesis
Q45540633Loss of Xist RNA from the inactive X during B cell development is restored in a dynamic YY1-dependent two-step process in activated B cells.
Q38625949Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression
Q64902350Mapping transcriptome-wide protein-RNA interactions to elucidate RNA regulatory programs.
Q59341183Mass Spectrometry-Based Proteomics to Unveil the Non-coding RNA World
Q26752329Mechanisms of long noncoding RNA function in development and disease
Q52490611Mechanistic insights in X-chromosome inactivation.
Q49169448Melanoma addiction to the long non-coding RNA SAMMSON.
Q38845439Methods to Study Long Noncoding RNA Biology in Cancer
Q91907958Methods to study RNA-protein interactions
Q52943679Molecular biology: Rap and chirp about X inactivation.
Q36805430NPInter v3.0: an upgraded database of noncoding RNA-associated interactions
Q33853235New frontiers in translational control of the cancer genome
Q92960431Non-Coding RNA Regulates the Myogenesis of Skeletal Muscle Satellite Cells, Injury Repair and Diseases
Q91849354Non-Coding RNAs and their Integrated Networks
Q92062051Non-coding RNA MFI2-AS1 promotes colorectal cancer cell proliferation, migration and invasion through miR-574-5p/MYCBP axis
Q87323041Non-coding RNA: X chromosome inactivation unravelled
Q87267201Non-coding RNA: X-chromosome inactivation unravelled
Q38826549Non-coding RNAs: Classification, Biology and Functioning
Q47880484Noncoding RNAs in neurodegeneration
Q46795621Notch Signaling in Development, Tissue Homeostasis, and Disease
Q39159965Novel players in X inactivation: insights into Xist-mediated gene silencing and chromosome conformation
Q49715418Nuclear Long Noncoding RNAs: Key Regulators of Gene Expression
Q89206071Nuclear lncRNA stabilization in the host response to bacterial infection
Q91594206PRC1 collaborates with SMCHD1 to fold the X-chromosome and spread Xist RNA between chromosome compartments
Q33563215PRC2 is dispensable for HOTAIR-mediated transcriptional repression
Q58782584Perturbed maintenance of transcriptional repression on the inactive X-chromosome in the mouse brain after Xist deletion
Q64326917Platforms for Investigating LncRNA Functions
Q42281728Polycomb complexes in X chromosome inactivation.
Q52430885Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome.
Q38974963Post-transcriptional mending of gene sequences: Looking under the hood of mitochondrial gene expression in diplonemids
Q49599791Preliminary screening and identification of differentially expressed metastasis-related ncRNAs in ovarian cancer
Q39458571Probing Long Non-coding RNA-Protein Interactions.
Q89565412Probing the function of long noncoding RNAs in the nucleus
Q27691278Progress and challenges for chemical probing of RNA structure inside living cells
Q53059503Progress in understanding the molecular mechanism of Xist RNA function through genetics.
Q41186092Proteomics to study DNA-bound and chromatin-associated gene regulatory complexes
Q92218442Proximity labeling to detect RNA-protein interactions in live cells
Q34554885Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip
Q35903512Purification of Messenger Ribonucleoprotein Particles via a Tagged Nascent Polypeptide
Q38287607Purification of Transcript-Specific mRNP Complexes Formed In Vivo from Saccharomyces cerevisiae
Q34485606Putting Non-coding RNA on Display with CRISPR.
Q89682682Quantitative Proteomics to Identify Nuclear RNA-Binding Proteins of Malat1
Q46428030Quantitative predictions of protein interactions with long noncoding RNAs
Q46211399RAP-MS: A Method to Identify Proteins that Interact Directly with a Specific RNA Molecule in Cells
Q47124980RATA: A method for high-throughput identification of RNA bound transcription factors
Q92203062RETRACTED: A 5' fragment of Xist can sequester RNA produced from adjacent genes on chromatin
Q30460141RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure
Q37730222RNA and Proteins: Mutual Respect
Q39373700RNA-mediated regulation of heterochromatin
Q90468329RNA-modifying enzymes and their function in a chromatin context
Q48106074RNA-protein interaction detection in living cells.
Q91985798RNA: interactions drive functionalities
Q111459478RNA–protein interactomes as invaluable resources to study RNA viruses: Insights from SARS CoV‐2 studies
Q36251661Random X-chromosome inactivation dynamics in vivo by single-cell RNA sequencing
Q45989856Re-evaluating the foundations of lncRNA-Polycomb function.
Q90267391Recent Advances in Understanding the Reversal of Gene Silencing During X Chromosome Reactivation
Q28077685Recent advances in Entamoeba biology: RNA interference, drug discovery, and gut microbiome
Q46628685Regulation of X-chromosome dosage compensation in human: mechanisms and model systems
Q91292216Regulation of gene expression by cis-acting long non-coding RNAs
Q47635276Repeat E anchors Xist RNA to the inactive X chromosomal compartment through CDKN1A-interacting protein (CIZ1).
Q44916722Response to Comment on "Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing".
Q90265148Review of the "X chromosome-nucleolus nexus" hypothesis of autoimmune diseases with an update explaining disruption of the nucleolus
Q35971227Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP).
Q28078986Role of lncRNAs in Cellular Aging
Q92671574Role of lncRNAs in aging and age-related diseases
Q90169460Role of nuclear RNA in regulating chromatin structure and transcription
Q26739676Roles of long noncoding RNAs in chromosome domains
Q39190884SAF-A Regulates Interphase Chromosome Structure through Oligomerization with Chromatin-Associated RNAs
Q58105949SAMMSON fosters cancer cell fitness by concertedly enhancing mitochondrial and cytosolic translation
Q37264182SHAPE reveals transcript-wide interactions, complex structural domains, and protein interactions across the Xist lncRNA in living cells.
Q56983776SILAC-MS Profiling of Reconstituted Human Chromatin Platforms for the Study of Transcription and RNA Regulation
Q89055234SMCHD1 Merges Chromosome Compartments and Assists Formation of Super-Structures on the Inactive X
Q89557250SPEN integrates transcriptional and epigenetic control of X-inactivation
Q41590310SPEN, a new player in primary cilia formation and cell migration in breast cancer
Q47672495Sample Preparation for Mass Spectrometry-based Identification of RNA-binding Regions.
Q36265896Screen for reactivation of MeCP2 on the inactive X chromosome identifies the BMP/TGF-β superfamily as a regulator of XIST expression.
Q55339874Screening and characterisation of sex differentiation-related long non-coding RNAs in Chinese soft-shell turtle (Pelodiscus sinensis).
Q36498407Sex-specific silencing of X-linked genes by Xist RNA.
Q38636633Short and long non-coding RNAs regulate the epigenetic status of cells
Q48611789Single particle imaging of mRNAs crossing the nuclear pore: Surfing on the edge
Q38552741Sound of silence: the properties and functions of repressive Lys methyltransferases.
Q38288209Specific RNP capture with antisense LNA/DNA mixmers.
Q60053979Spen limits intestinal stem cell self-renewal
Q102152196Spen modulates lipid droplet content in adult Drosophila glial cells and protects against paraquat toxicity
Q39385283State of the art technologies to explore long non-coding RNAs in cancer.
Q42053143Structural aspects of the inactive X chromosome
Q103836656Structural modularity of the XIST ribonucleoprotein complex
Q33725284Structural organization of the inactive X chromosome in the mouse.
Q37285424Structural, super-resolution microscopy analysis of paraspeckle nuclear body organization
Q91891716Super-Enhancer-Associated LncRNA UCA1 Interacts Directly with AMOT to Activate YAP Target Genes in Epithelial Ovarian Cancer
Q37024604Synthetic tetracycline-controllable shRNA targeting long non-coding RNA HOXD-AS1 inhibits the progression of bladder cancer
Q91936605Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation
Q90038222Tales from topographic oceans: topologically associated domains and cancer
Q38595464Targeting Polycomb systems to regulate gene expression: modifications to a complex story
Q38752040Targeting noncoding RNAs in disease
Q42777373Technological Developments in lncRNA Biology
Q46162198Ten principles of heterochromatin formation and function.
Q26750498The "lnc" between 3D chromatin structure and X chromosome inactivation
Q41686790The 4D nucleome project
Q46302412The 5' region of Xist RNA has the potential to associate with chromatin through the A-repeat
Q89667139The B-side of Xist
Q47101298The Dark Side of the Epitranscriptome: Chemical Modifications in Long Non-Coding RNAs
Q52348414The Ever-Evolving Concept of the Gene: The Use of RNA/Protein Experimental Techniques to Understand Genome Functions.
Q90164355The Growth-Arrest-Specific (GAS)-5 Long Non-Coding RNA: A Fascinating lncRNA Widely Expressed in Cancers
Q60912528The Implication of Early Chromatin Changes in X Chromosome Inactivation
Q39927058The Inescapable Influence of Noncoding RNAs in Cancer
Q38758644The MBNL3 splicing factor promotes hepatocellular carcinoma by increasing PXN expression through the alternative splicing of lncRNA-PXN-AS1.
Q55381359The Methylome of Vertebrate Sex Chromosomes.
Q59055464The NORAD lncRNA assembles a topoisomerase complex critical for genome stability
Q90293256The Non-random Location of Autosomal Genes That Participate in X Inactivation
Q89129149The Role of Xist in X-Chromosome Dosage Compensation
Q64108233The Roles of Human DNA Methyltransferases and Their Isoforms in Shaping the Epigenome
Q104438472The SARS-CoV-2 RNA interactome
Q107138386The SARS-CoV-2 RNA interactome
Q107133553The SARS-CoV-2 RNA-protein interactome in infected human cells
Q54980063The STAT3 Target Mettl8 Regulates Mouse ESC Differentiation via Inhibiting the JNK Pathway.
Q46262964The Secret Life of RNA: Lessons from Emerging Methodologies
Q37654550The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition
Q39289403The X chromosome in space
Q41880817The binding specificity of Translocated in LipoSarcoma/FUsed in Sarcoma with lncRNA transcribed from the promoter region of cyclin D1.
Q38647501The contribution of mass spectrometry-based proteomics to understanding epigenetics
Q60738239The eXceptional nature of the X chromosome
Q40065180The emerging molecular biology toolbox for the study of long noncoding RNA biology
Q46920734The functions and unique features of long intergenic non-coding RNA.
Q42278258The interaction of PRC2 with RNA or chromatin is mutually antagonistic
Q36786592The interplay of long non-coding RNAs and MYC in cancer
Q47794690The large and small SPEN family proteins stimulate axon outgrowth during neurosecretory cell remodeling in Drosophila
Q37190414The long non-coding RNA EPB41L4A-AS2 inhibits tumor proliferation and is associated with favorable prognoses in breast cancer and other solid tumors
Q91451568The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia
Q33720269The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells
Q47927500The long noncoding RNA SNHG1 promotes tumor growth through regulating transcription of both local and distal genes
Q41323652The long noncoding RNA XIAP-AS1 promotes XIAP transcription by XIAP-AS1 interacting with Sp1 in gastric cancer cells
Q52611753The long tail of oncogenic drivers in prostate cancer.
Q33882267The m6A pathway facilitates sex determination in Drosophila.
Q38568659The making of a Barr body: the mosaic of factors that eXIST on the mammalian inactive X chromosome
Q60921893The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome
Q92036380The noncoding function of NELFA mRNA promotes the development of oesophageal squamous cell carcinoma by regulating the Rad17-RFC2-5 complex
Q33763595The nuclear matrix protein CIZ1 facilitates localization of Xist RNA to the inactive X-chromosome territory
Q47259543The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes
Q99595515The physiological function of long-noncoding RNAs
Q30459862The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2.
Q46549812The repetitive DNA element BncDNA, enriched in the B chromosome of the cichlid fish Astatotilapia latifasciata, transcribes a potentially noncoding RNA.
Q92917837The role of Xist-mediated Polycomb recruitment in the initiation of X-chromosome inactivation
Q92909165The role of epigenetics and chromatin structure in transcriptional regulation in malaria parasites
Q41357008The role of interactions of long non-coding RNAs and heterogeneous nuclear ribonucleoproteins in regulating cellular functions
Q49596604The role of long non-coding RNAs in rheumatic diseases
Q91654091The role of the Xist 5' m6A region and RBM15 in X chromosome inactivation
Q92461048The role of transcription in shaping the spatial organization of the genome
Q98613214Thermal-responsive genetic and epigenetic regulation of DAM cluster controlling dormancy and chilling requirement in peach floral buds
Q37232922Tissue-specific Co-expression of Long Non-coding and Coding RNAs Associated with Breast Cancer
Q103028179Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome
Q93166268Transcript specific mRNP capture from Drosophila egg-chambers for proteomic analysis
Q89185640Transcriptional modulation of entire chromosomes: dosage compensation
Q59801852Transcriptome Analysis of Long Non-Coding RNA in the Bovine Mammary Gland Following Dietary Supplementation with Linseed Oil and Safflower Oil
Q59798011UPA-seq: prediction of functional lncRNAs using differential sensitivity to UV crosslinking
Q35886207Uncovering the roles of long noncoding RNAs in neural development and glioma progression
Q91808764Understanding Long Noncoding RNA and Chromatin Interactions: What We Know So Far
Q36802536Unusual maintenance of X chromosome inactivation predisposes female lymphocytes for increased expression from the inactive X
Q93074975Unveiling the druggable RNA targets and small molecule therapeutics
Q26779139Unveiling the hidden function of long non-coding RNA by identifying its major partner-protein
Q50463042Visualizing the secondary and tertiary architectural domains of lncRNA RepA.
Q46300721When the Lyon(ized chromosome) roars: ongoing expression from an inactive X chromosome
Q36587843Widespread RNA binding by chromatin-associated proteins
Q26801274X Inactivation Lessons from Differentiating Mouse Embryonic Stem Cells
Q37730204X chromosome inactivation: new players in the initiation of gene silencing
Q36396148X chromosome reactivation in reprogramming and in development
Q36782721X-chromosome inactivation and escape
Q37574662XACT Noncoding RNA Competes with XIST in the Control of X Chromosome Activity during Human Early Development.
Q41770801XIST RNA: a window into the broader role of RNA in nuclear chromosome architecture.
Q92084159Xist Deletional Analysis Reveals an Interdependency between Xist RNA and Polycomb Complexes for Spreading along the Inactive X
Q91142810Xist RNA antagonizes the SWI/SNF chromatin remodeler BRG1 on the inactive X chromosome
Q90180450Xist RNA in action: Past, present, and future
Q90472616Xist attenuates acute inflammatory response by female cells
Q26797489Xist localization and function: new insights from multiple levels
Q34536478Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing.
Q37536541Xist reduction in breast cancer upregulates AKT phosphorylation via HDAC3-mediated repression of PHLPP1 expression.
Q38630891lnc00673 (ERRLR01) is a Prognostic Indicator of Overall Survival in Breast Cancer.
Q41225381lncRNAs in development and disease: from functions to mechanisms
Q26775906lncRNAs regulate the innate immune response to viral infection
Q93010867lncRedibly versatile: biochemical and biological functions of long noncoding RNAs
Q33902260m(6)A RNA methylation promotes XIST-mediated transcriptional repression
Q36079109spenito is required for sex determination in Drosophila melanogaster

Q59667368Mitchell Guttmannotable workP800

Search more.