Coherent functional modules improve transcription factor target identification, cooperativity prediction, and disease association

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Coherent functional modules improve transcription factor target identification, cooperativity prediction, and disease association is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1004122
P932PMC publication ID3916285
P698PubMed publication ID24516403
P5875ResearchGate publication ID260154710

P50authorRuss AltmanQ7381092
Michael P. SnyderQ28924918
Nicholas P. TatonettiQ39888223
Konrad J. KarczewskiQ47502873
P2860cites workIdentification and analysis of functional elements in 1% of the human genome by the ENCODE pilot projectQ21061203
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Potential etiologic and functional implications of genome-wide association loci for human diseases and traitsQ22066284
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Mutation of the SNF2 family member Chd2 affects mouse development and survivalQ79818290
Membrane translocation of small GTPase Rac1 and activation of STAT1 and STAT3 in pacing-induced sustained atrial fibrillationQ81935169
Identification and characterization of human ZNF274 cDNA, which encodes a novel kruppel-type zinc-finger protein having nucleolar targeting abilityQ22253966
ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genesQ24318366
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteinsQ24685694
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The genetic association databaseQ29617244
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Module networks: identifying regulatory modules and their condition-specific regulators from gene expression dataQ29618517
Independent component analysis: mining microarray data for fundamental human gene expression modulesQ33629605
Variation in transcription factor binding among humansQ34105133
Role of apoptosis signal-regulating kinase-1-c-Jun NH2-terminal kinase-p38 signaling in voltage-gated K+ channel remodeling of the failing heart: regulation by thioredoxinQ34399275
Nucleosome-mediated cooperativity between transcription factorsQ34450175
NFAT and IRF Proteins Regulate Transcription of the Anti-HIV Gene, APOBEC3GQ34509329
Network component analysis: reconstruction of regulatory signals in biological systemsQ34788818
Combinatorial binding predicts spatio-temporal cis-regulatory activityQ35011328
Computational modeling of mammalian signaling networksQ35018212
Cooperative transcription factor associations discovered using regulatory variationQ35164635
Absence of SOCS3 in the Cardiomyocyte Increases Mortality in a gp130-Dependent Manner Accompanied by Contractile Dysfunction and Ventricular ArrhythmiasQ35660566
Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATFQ35889683
Genetic variants predisposing to cardiovascular diseaseQ36419139
Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regionsQ37309445
Genetic analysis of variation in transcription factor binding in yeastQ38345613
Induction of high STAT1 expression in transgenic mice with LQTS and heart failureQ41970628
Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cellsQ42793741
Interactions of MinK and e-NOS gene polymorphisms appear to be inconsistent predictors of atrial fibrillation propensity, but long alleles of ESR1 promoter TA repeat may be a promising markerQ43254222
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesCytoscapeQ3699942
P433issue2
P304page(s)e1004122
P577publication date2014-02-06
P1433published inPLOS GeneticsQ1893441
P1476titleCoherent functional modules improve transcription factor target identification, cooperativity prediction, and disease association
P478volume10

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cites work (P2860)
Q55298516A comprehensive evaluation of module detection methods for gene expression data.
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Q97870680Independent component analysis of E. coli's transcriptome reveals the cellular processes that respond to heterologous gene expression
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Q38515038Post-translational modifications of hormone-responsive transcription factors: the next level of regulation.
Q35728153TRRUST: a reference database of human transcriptional regulatory interactions
Q55515377Tensor Decomposition-Based Unsupervised Feature Extraction Can Identify the Universal Nature of Sequence-Nonspecific Off-Target Regulation of mRNA Mediated by MicroRNA Transfection.
Q91665941The Escherichia coli transcriptome mostly consists of independently regulated modules
Q44511470The Populus ARBORKNOX1 homeodomain transcription factor regulates woody growth through binding to evolutionarily conserved target genes of diverse function.
Q36262509The genetic regulatory network centered on Pto-Wuschela and its targets involved in wood formation revealed by association studies
Q37140821Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseases

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