Kaposi's sarcoma-associated herpesvirus-encoded LANA interacts with host KAP1 to facilitate establishment of viral latency

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Kaposi's sarcoma-associated herpesvirus-encoded LANA interacts with host KAP1 to facilitate establishment of viral latency is …
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scholarly articleQ13442814

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P356DOI10.1128/JVI.00596-14
P932PMC publication ID4054432
P698PubMed publication ID24741090

P2093author name stringYuan Gao
Deguang Liang
Ke Lan
Rui Sun
P2860cites workModel-based analysis of ChIP-Seq (MACS)Q21183902
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Physical and functional interactions between STAT3 and Kaposi's sarcoma-associated herpesvirus-encoded LANAQ24299259
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Human herpesvirus 8 LANA interacts with proteins of the mSin3 corepressor complex and negatively regulates Epstein-Barr virus gene expression in dually infected PEL cellsQ24527215
Carboxy terminus of human herpesvirus 8 latency-associated nuclear antigen mediates dimerization, transcriptional repression, and targeting to nuclear bodies.Q24531182
Protein interactions targeting the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus to cell chromosomesQ24538878
Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRDQ24602561
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A Structural Basis for BRD2/4-Mediated Host Chromatin Interaction and Oligomer Assembly of Kaposi Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus LANA ProteinsQ27680409
Molecular Basis for Oligomeric-DNA Binding and Episome Maintenance by KSHV LANAQ27680411
Crystal Structure of the Gamma-2 Herpesvirus LANA DNA Binding Domain Identifies Charged Surface Residues Which Impact Viral LatencyQ27680412
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KRAB-zinc finger proteins and KAP1 can mediate long-range transcriptional repression through heterochromatin spreadingQ28473103
A unique SUMO-2-interacting motif within LANA is essential for KSHV latencyQ28535343
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Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's diseaseQ29619158
Kaposi's sarcoma-associated herpesvirus-encoded LANA can interact with the nuclear mitotic apparatus protein to regulate genome maintenance and segregationQ30482603
A novel KRAB-Zinc finger protein interacts with latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus and activates transcription via terminal repeat sequencesQ33265370
Protein complexes associated with the Kaposi's sarcoma-associated herpesvirus-encoded LANA.Q33282107
A viral gene that activates lytic cycle expression of Kaposi’s sarcoma-associated herpesvirusQ33559699
Early and sustained expression of latent and host modulating genes in coordinated transcriptional program of KSHV productive primary infection of human primary endothelial cellsQ33623056
Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: Maintenance of tight latency with efficient reactivation upon inductionQ39573744
Human I-mfa domain proteins specifically interact with KSHV LANA and affect its regulation of Wnt signaling-dependent transcriptionQ39711148
DNA-PK/Ku complex binds to latency-associated nuclear antigen and negatively regulates Kaposi's sarcoma-associated herpesvirus latent replication.Q39725564
Distinct p53, p53:LANA, and LANA complexes in Kaposi's Sarcoma--associated Herpesvirus LymphomasQ39744147
Kaposi's sarcoma-associated herpesvirus Lana-1 is a major activator of the serum response element and mitogen-activated protein kinase pathways via interactions with the Mediator complexQ39749787
Poly(ADP-ribose) polymerase 1 binds to Kaposi's sarcoma-associated herpesvirus (KSHV) terminal repeat sequence and modulates KSHV replication in latencyQ39959766
Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus up-regulates transcription of human telomerase reverse transcriptase promoter through interaction with transcription factor Sp1.Q39992257
Productive lytic replication of a recombinant Kaposi's sarcoma-associated herpesvirus in efficient primary infection of primary human endothelial cellsQ39996542
Disruption of Kaposi's sarcoma-associated herpesvirus latent nuclear antigen leads to abortive episome persistenceQ40163096
The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA.Q40318272
Transcriptional coactivation of c-Jun by the KSHV-encoded LANA.Q40635358
Hypoxia induces lytic replication of Kaposi sarcoma-associated herpesvirusQ40807418
Establishment and characterization of a primary effusion (body cavity-based) lymphoma cell line (BC-3) harboring kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in the absence of Epstein-Barr virus.Q41164451
Kaposi's sarcoma-associated herpesvirus latent protein LANA interacts with HIF-1 alpha to upregulate RTA expression during hypoxia: Latency control under low oxygen conditionsQ42049779
The Transcriptional Activity of cAMP Response Element-binding Protein-binding Protein Is Modulated by the Latency Associated Nuclear Antigen of Kaposi's Sarcoma-associated HerpesvirusQ57662902
Transcription profile of Kaposi's sarcoma-associated herpesvirus in primary Kaposi's sarcoma lesions as determined by real-time PCR arraysQ73344152
Valproic acid induces human herpesvirus 8 lytic gene expression in BCBL-1 cellsQ73854104
Reactivation of Kaposi's sarcoma-associated herpesvirus infection from latency by expression of the ORF 50 transactivator, a homolog of the EBV R proteinQ77760836
Induction of human herpesvirus-8 DNA replication and transcription by butyrate and TPA in BCBL-1 cellsQ77957842
Strep/FLAG tandem affinity purification (SF-TAP) to study protein interactionsQ84423124
Epigenetic analysis of KSHV latent and lytic genomesQ33641399
Kaposi's sarcoma-associated herpesvirus reactivation is regulated by interaction of latency-associated nuclear antigen with recombination signal sequence-binding protein Jkappa, the major downstream effector of the Notch signaling pathwayQ33737793
Latent nuclear antigen of Kaposi's sarcoma-associated herpesvirus interacts with RING3, a homolog of the Drosophila female sterile homeotic (fsh) geneQ33824419
The latency-associated nuclear antigen of rhesus monkey rhadinovirus inhibits viral replication through repression of Orf50/Rta transcriptional activationQ33834414
Induction of Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen by the lytic transactivator RTA: a novel mechanism for establishment of latencyQ33843211
DNA binding and modulation of gene expression by the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirusQ33853499
Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigenQ33859518
Transcription Mapping of the Kaposi’s Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Genome in a Body Cavity-Based Lymphoma Cell Line (BC-1)Q34069105
Kaposi's sarcoma-associated herpesvirus: a new DNA tumor virusQ34132022
A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere shortening.Q34179693
Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen inhibits lytic replication by targeting Rta: a potential mechanism for virus-mediated control of latencyQ34194120
The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus supports latent DNA replication in dividing cellsQ34355092
The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cellsQ34511161
A novel viral mechanism for dysregulation of beta-catenin in Kaposi's sarcoma-associated herpesvirus latency.Q34531461
Acetylation of the latency-associated nuclear antigen regulates repression of Kaposi's sarcoma-associated herpesvirus lytic transcription.Q34648229
Mechanisms of Kaposi's Sarcoma-Associated Herpesvirus Latency and ReactivationQ35010647
Recruitment of the de novo DNA methyltransferase Dnmt3a by Kaposi's sarcoma-associated herpesvirus LANAQ35080754
Functional analysis of KAP1 genomic recruitmentQ35096261
Accumulation of heterochromatin components on the terminal repeat sequence of Kaposi's sarcoma-associated herpesvirus mediated by the latency-associated nuclear antigenQ35123088
Ribosomal Protein S6 Interacts with the Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated HerpesvirusQ35192690
Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen and Angiogenin Interact with Common Host Proteins, Including Annexin A2, Which Is Essential for Survival of Latently Infected CellsQ35689577
Post-Translational Modifications of Kaposi’s Sarcoma-Associated Herpesvirus Regulatory Proteins – SUMO and KSHVQ35755464
Protein arginine methyltransferase 1-directed methylation of Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigenQ35774091
Identification of Host-Chromosome Binding Sites and Candidate Gene Targets for Kaposi's Sarcoma-Associated Herpesvirus LANAQ35943531
Carboxyl-terminal amino acids 1052 to 1082 of the latency-associated nuclear antigen (LANA) interact with RBP-Jκ and are responsible for LANA-mediated RTA repression.Q35943718
Roles of Kruppel-associated Box (KRAB)-associated Co-repressor KAP1 Ser-473 Phosphorylation in DNA Damage ResponseQ36003622
The Kaposi's sarcoma-associated herpesvirus LANA protein stabilizes and activates c-MycQ36099076
KSHV LANA inhibits TGF-beta signaling through epigenetic silencing of the TGF-beta type II receptorQ36591375
Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen regulates the KSHV epigenome by association with the histone demethylase KDM3A.Q36911800
Concurrent expression of latent and a limited number of lytic genes with immune modulation and antiapoptotic function by Kaposi's sarcoma-associated herpesvirus early during infection of primary endothelial and fibroblast cells and subsequent declinQ37010247
Genetic disruption of KSHV major latent nuclear antigen LANA enhances viral lytic transcriptional programQ37060535
Regulation of episomal gene expression by KRAB/KAP1-mediated histone modificationsQ37191839
Kruppel-associated box domain-associated protein-1 as a latency regulator for Kaposi's sarcoma-associated herpesvirus and its modulation by the viral protein kinaseQ37317681
KAP1 protein: an enigmatic master regulator of the genomeQ37886421
P433issue13
P304page(s)7331-7344
P577publication date2014-04-16
P1433published inJournal of VirologyQ1251128
P1476titleKaposi's sarcoma-associated herpesvirus-encoded LANA interacts with host KAP1 to facilitate establishment of viral latency
P478volume88

Reverse relations

cites work (P2860)
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