| scholarly article | Q13442814 |
| P50 | author | David S Booth | Q55292895 |
| P2093 | author name string | Alan D Frankel | |
| Gwendolyn M Jang | |||
| Iván D'Orso | |||
| Tyler B Faust | |||
| Alexander W Pastuszak | |||
| Elizabeth Quezada | |||
| P2860 | cites work | Gene activation by recruitment of the RNA polymerase II holoenzyme | Q71574606 |
| Protein stability effects of a complete set of alanine substitutions in Arc repressor | Q72033250 | ||
| The meaning of pausing | Q82543796 | ||
| Kick-sTARting HIV-1 transcription elongation by 7SK snRNP deporTATion | Q84654190 | ||
| The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK | Q21136168 | ||
| Tools for integrated sequence-structure analysis with UCSF Chimera | Q21284249 | ||
| Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro | Q22008559 | ||
| Function and structure of inherently disordered proteins | Q22061740 | ||
| Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme | Q24321455 | ||
| PITALRE, the catalytic subunit of TAK, is required for human immunodeficiency virus Tat transactivation in vivo | Q24523183 | ||
| CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA | Q24550765 | ||
| Relief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter | Q24552532 | ||
| Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor | Q24563382 | ||
| Human immunodeficiency virus type-1 Tat is an integral component of the activated transcription-elongation complex | Q24568316 | ||
| c-Myc regulates transcriptional pause release | Q24629119 | ||
| 7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcription | Q24634280 | ||
| Crystal structure of HIV-1 Tat complexed with human P-TEFb | Q24634569 | ||
| LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated | Q24646322 | ||
| Three functional classes of transcriptional activation domain | Q24649917 | ||
| HIV-1 Tat stimulates transcription complex assembly through recruitment of TBP in the absence of TAFs | Q24797317 | ||
| Preformed Protein-binding Motifs in 7SK snRNA: Structural and Thermodynamic Comparisons with Retroviral TAR | Q27664269 | ||
| The super elongation complex (SEC) and MLL in development and disease | Q27692038 | ||
| An activator target in the RNA polymerase II holoenzyme | Q27938223 | ||
| Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription | Q28116305 | ||
| 7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes | Q28116607 | ||
| Tat-associated kinase (P-TEFb): a component of transcription preinitiation and elongation complexes | Q28138220 | ||
| NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation | Q28141291 | ||
| Transcriptional coactivator complexes | Q28200751 | ||
| HIV-1 Tat: Its Dependence on Host Factors is Crystal Clear | Q42767857 | ||
| Evidence for conformational flexibility in the Tat-TAR recognition motif of cyclin T1. | Q42831352 | ||
| An RNA-binding chameleon | Q43634596 | ||
| Transcriptional but not translational regulation of HIV-1 by the tat gene product. | Q44298589 | ||
| Mutational analysis of HIV-1 Tat minimal domain peptides: identification of trans-dominant mutants that suppress HIV-LTR-driven gene expression | Q44389543 | ||
| VP16 and ubiquitin; binding of P-TEFb via its activation domain and ubiquitin facilitates elongation of transcription of target genes | Q44940991 | ||
| Atomistic details of the disordered states of KID and pKID. Implications in coupled binding and folding | Q45214738 | ||
| Commitment to splice site pairing coincides with A complex formation | Q46357841 | ||
| RNA emerging from the active site of RNA polymerase II interacts with the Rpb7 subunit | Q46835516 | ||
| Alanine scanning of MS2 coat protein reveals protein-phosphate contacts involved in thermodynamic hot spots | Q46869803 | ||
| Activator-mediated recruitment of the RNA polymerase II machinery is the predominant mechanism for transcriptional activation in yeast | Q47858045 | ||
| Transcriptional elongation by RNA polymerase II is stimulated by transactivators. | Q49101405 | ||
| Systematic mutation of bacteriophage T4 lysozyme | Q50183536 | ||
| A tethering approach to study proteins that activate mRNA turnover in human cells. | Q51961049 | ||
| TFIID sequence recognition of the initiator and sequences farther downstream in Drosophila class II genes. | Q52541449 | ||
| Trans-dominant Tat mutants with alterations in the basic domain inhibit HIV-1 gene expression. | Q54693468 | ||
| A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives. | Q54713263 | ||
| Purification and functional characterization of transcription factor SII from calf thymus. Role in RNA polymerase II elongation | Q64379819 | ||
| The HIV-1 Tat protein activates transcription from an upstream DNA-binding site: implications for Tat function | Q67782274 | ||
| The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription | Q28206012 | ||
| Stimulatory effect of splicing factors on transcriptional elongation | Q28214807 | ||
| Transcription elongation factor SII (TFIIS) enables RNA polymerase II to elongate through a block to transcription in a human gene in vitro | Q28237860 | ||
| Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat | Q28247078 | ||
| Activation of transcription by HIV-1 Tat protein tethered to nascent RNA through another protein | Q28247468 | ||
| Controlling the elongation phase of transcription with P-TEFb | Q28255518 | ||
| Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186 | Q28257440 | ||
| A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA | Q28263974 | ||
| HIV-1: fifteen proteins and an RNA | Q28284280 | ||
| P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro | Q28379179 | ||
| Hot spots for allosteric regulation on protein surfaces | Q28728550 | ||
| Open source clustering software | Q29547702 | ||
| Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro | Q29614788 | ||
| Evolutionarily conserved networks of residues mediate allosteric communication in proteins | Q29615036 | ||
| Transcriptional activation by recruitment | Q29615048 | ||
| Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product | Q29615049 | ||
| P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II | Q29620167 | ||
| HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation | Q29620799 | ||
| HIV-1 TAR RNA enhances the interaction between Tat and cyclin T1. | Q33292300 | ||
| Defining mechanisms that regulate RNA polymerase II transcription in vivo | Q33708432 | ||
| Controlling cellular P-TEFb activity by the HIV-1 transcriptional transactivator Tat | Q33728518 | ||
| A single intermolecular contact mediates intramolecular stabilization of both RNA and protein | Q33784415 | ||
| Characterization of the RNA content of chromatin | Q33940935 | ||
| Artificial recruitment of TFIID, but not RNA polymerase II holoenzyme, activates transcription in mammalian cells | Q33963967 | ||
| Modular structure of transcription factors: implications for gene regulation | Q34110705 | ||
| Trans-activation by HIV-1 Tat via a heterologous RNA binding protein | Q34156002 | ||
| Gene Q antiterminator proteins of Escherichia coli phages 82 and lambda suppress pausing by RNA polymerase at a rho-dependent terminator and at other sites | Q34289834 | ||
| Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation | Q34346839 | ||
| Function of a eukaryotic transcription activator during the transcription cycle | Q34415384 | ||
| Pol II waiting in the starting gates: Regulating the transition from transcription initiation into productive elongation. | Q34494012 | ||
| Breaking barriers to transcription elongation | Q34561019 | ||
| HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription | Q34896128 | ||
| Transcriptional activation by artificial recruitment in mammalian cells | Q35058517 | ||
| Specific interaction of Tat with the human but not rodent P-TEFb complex mediates the species-specific Tat activation of HIV-1 transcription | Q35059684 | ||
| Evolutionarily conserved surface residues constitute actin binding sites of tropomyosin | Q35064252 | ||
| The Yin and Yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation | Q35072999 | ||
| P-TEFb kinase recruitment and function at heat shock loci | Q35190358 | ||
| Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin | Q35202721 | ||
| The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein | Q35211232 | ||
| How the phage lambda N gene product suppresses transcription termination: communication of RNA polymerase with regulatory proteins mediated by signals in nascent RNA | Q35384285 | ||
| Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription. | Q35804608 | ||
| Inhibition of HIV-1 replication by P-TEFb inhibitors DRB, seliciclib and flavopiridol correlates with release of free P-TEFb from the large, inactive form of the complex | Q35940053 | ||
| Recruitment of cyclin T1/P-TEFb to an HIV type 1 long terminal repeat promoter proximal RNA target is both necessary and sufficient for full activation of transcription | Q36405698 | ||
| A new class of activation-defective TATA-binding protein mutants: evidence for two steps of transcriptional activation in vivo | Q36561614 | ||
| Promoter activity of Tat at steps subsequent to TATA-binding protein recruitment | Q36573810 | ||
| Structural analysis of wild-type and mutant human immunodeficiency virus type 1 Tat proteins | Q36796119 | ||
| Mutational analysis of the conserved cysteine-rich region of the human immunodeficiency virus type 1 Tat protein | Q36804564 | ||
| Tat acetylation modulates assembly of a viral-host RNA-protein transcription complex | Q37117705 | ||
| Poised polymerases: on your mark...get set...go! | Q37136094 | ||
| Protein-protein interaction and quaternary structure | Q37277360 | ||
| The basal initiation machinery: beyond the general transcription factors | Q37467909 | ||
| The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongation | Q37506941 | ||
| The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation | Q37799722 | ||
| Transient protein-protein interactions: structural, functional, and network properties | Q37800222 | ||
| The control of HIV transcription: keeping RNA polymerase II on track | Q37958430 | ||
| The HIV-1 Tat protein: an RNA sequence-specific processivity factor? | Q37976427 | ||
| Distinct transcriptional pathways of TAR-dependent and TAR-independent human immunodeficiency virus type-1 transactivation by Tat. | Q38343402 | ||
| Transcription regulation through promoter-proximal pausing of RNA polymerase II. | Q39442921 | ||
| The ability of positive transcription elongation factor B to transactivate human immunodeficiency virus transcription depends on a functional kinase domain, cyclin T1, and Tat. | Q39580108 | ||
| HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP | Q39703646 | ||
| Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR. | Q40118214 | ||
| Protein traffic on the heat shock promoter: parking, stalling, and trucking along | Q40826956 | ||
| Recruitment of the TATA-binding protein to the HIV-1 promoter is a limiting step for Tat transactivation | Q40994979 | ||
| HIV-1 Tat interacts with cyclin T1 to direct the P-TEFb CTD kinase complex to TAR RNA. | Q41675687 | ||
| TAR-independent activation of the HIV-1 LTR: evidence that tat requires specific regions of the promoter | Q41724573 | ||
| Transcriptional activation domains stimulate initiation and elongation at different times and via different residues | Q41810274 | ||
| High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis | Q41824916 | ||
| Targeting tat inhibitors in the assembly of human immunodeficiency virus type 1 transcription complexes | Q41973410 | ||
| RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation | Q42027880 | ||
| The Role of RNA Polymerase II Elongation Control in HIV-1 Gene Expression, Replication, and Latency | Q42117931 | ||
| Transcription control by long non-coding RNAs | Q42137522 | ||
| Yeast and human TFIID with altered DNA-binding specificity for TATA elements | Q42468243 | ||
| Genetic analysis of P-TEFb function via heterologous nucleic acid tethering systems. | Q42558651 | ||
| Functional mapping of the surface residues of human thrombin | Q42679721 | ||
| P433 | issue | 23 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | HIV | Q15787 |
| P304 | page(s) | 4780-4793 | |
| P577 | publication date | 2012-09-24 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Transition step during assembly of HIV Tat:P-TEFb transcription complexes and transfer to TAR RNA | |
| P478 | volume | 32 |
| Q47266352 | AID recruits the RNA exosome to degrade HIV-1 nascent transcripts through interaction with the Tat-P-TEFb-TAR RNP complex |
| Q41440692 | Building a super elongation complex for HIV. |
| Q27683254 | Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4 |
| Q38995028 | Cyclin-dependent kinases as therapeutic targets for HIV-1 infection. |
| Q91959762 | Face-time with TAR: Portraits of an HIV-1 RNA with diverse modes of effector recognition relevant for drug discovery |
| Q92135927 | Genetic variation and function of the HIV-1 Tat protein |
| Q36520900 | HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells |
| Q57464694 | HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry |
| Q48219788 | Hexim1, an RNA-controlled protein hub. |
| Q36274198 | MD simulation of the Tat/Cyclin T1/CDK9 complex revealing the hidden catalytic cavity within the CDK9 molecule upon Tat binding |
| Q35597624 | MYB elongation is regulated by the nucleic acid binding of NFκB p50 to the intronic stem-loop region. |
| Q33602605 | Negative elongation factor is required for the maintenance of proviral latency but does not induce promoter-proximal pausing of RNA polymerase II on the HIV long terminal repeat |
| Q40272529 | PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription |
| Q40669160 | Quantification of the HIV transcriptional activator complex in live cells by image-based protein-protein interaction analysis |
| Q38430337 | Role of Host Factors on the Regulation of Tat-Mediated HIV-1 Transcription |
| Q26782187 | Roles of microRNAs and long-noncoding RNAs in human immunodeficiency virus replication |
| Q89266907 | Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7 |
| Q61814094 | TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb |
| Q27676733 | The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat |
| Q54216806 | The HIV-1 Tat protein enhances splicing at the major splice donor site. |
| Q54977707 | The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation. |
| Q40135003 | The HIV-1 Tat protein: mechanism of action and target for HIV-1 cure strategies. |
| Q37194356 | Transcription elongation control by the 7SK snRNP complex: Releasing the pause. |
| Q41853689 | Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation. |
| Q64083933 | Transcriptional Circuit Fragility Influences HIV Proviral Fate |
| Q26999858 | Transcriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cure |
| Q34134540 | Unperturbed posttranscriptional regulatory Rev protein function and HIV-1 replication in astrocytes |
| Q27728130 | hLARP7 C-terminal domain contains an xRRM that binds the 3' hairpin of 7SK RNA |
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