| P50 | author | Annemieke A Michels | Q55293692 |
| P2093 | author name string | Olivier Bensaude | |
| P2860 | cites work | Inhibition of Tat activity by the HEXIM1 protein | Q21245206 |
| | Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells | Q24294541 |
| | Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription | Q24294985 |
| | HEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SK | Q24294998 |
| | HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b | Q24304885 |
| | A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb | Q24561968 |
| | Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor | Q24563382 |
| | The Drosophila 7SK snRNP and the essential role of dHEXIM in development | Q24597477 |
| | Crystal structure of HIV-1 Tat complexed with human P-TEFb | Q24634569 |
| | MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner | Q24679741 |
| | Getting up to speed with transcription elongation by RNA polymerase II | Q27023288 |
| | Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb | Q27647591 |
| | 7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes | Q28116607 |
| | Specificity of Hexim1 and Hexim2 complex formation with cyclin T1/T2, importin alpha and 7SK snRNA | Q28117712 |
| | Identification of a novel inhibitor of breast cell growth that is down-regulated by estrogens and decreased in breast tumors | Q28203806 |
| | The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription | Q28206012 |
| | 7SK RNA, a non-coding RNA regulating P-TEFb, a general transcription factor | Q28236590 |
| | Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation | Q28240747 |
| | Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat | Q28247078 |
| | The breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1 | Q28254964 |
| | Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186 | Q28257440 |
| | Transcription-dependent association of multiple positive transcription elongation factor units to a HEXIM multimer | Q28259610 |
| | Cracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFb | Q28276848 |
| | SR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymerase | Q28512917 |
| | Ablation of the CLP-1 gene leads to down-regulation of the HAND1 gene and abnormality of the left ventricle of the heart and fetal death | Q28513084 |
| | Identification of a novel cardiac lineage-associated protein(cCLP-1): A candidate regulator of cardiogenesis | Q30654606 |
| | HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription | Q30835037 |
| | Phosphatase PPM1A regulates phosphorylation of Thr-186 in the Cdk9 T-loop | Q33373237 |
| | Induction of HEXIM1 activities by HMBA derivative 4a1: Functional consequences and mechanism | Q33432584 |
| | The control of HIV transcription: keeping RNA polymerase II on track | Q37958430 |
| | RNA polymerase II elongation control | Q37992154 |
| | Disorder-function relationships for the cell cycle regulatory proteins p21 and p27. | Q38048787 |
| | SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription | Q38706788 |
| | HMBA is a putative HSP70 activator stimulating HEXIM1 expression that is down-regulated by estrogen | Q38715966 |
| | Ubenimex enhances Brd4 inhibition by suppressing HEXIM1 autophagic degradation and suppressing the Akt pathway in glioma cells | Q38796928 |
| | HEXIM1 plays a critical role in the inhibition of the androgen receptor by anti-androgens | Q38993411 |
| | Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA. | Q39235226 |
| | Transition step during assembly of HIV Tat:P-TEFb transcription complexes and transfer to TAR RNA. | Q39272683 |
| | Nucleophosmin interacts with HEXIM1 and regulates RNA polymerase II transcription | Q39997668 |
| | Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR. | Q40118214 |
| | HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response | Q40120999 |
| | Regulation of polymerase II transcription by 7SK snRNA: two distinct RNA elements direct P-TEFb and HEXIM1 binding | Q40335491 |
| | DDX6 transfers P-TEFb kinase to the AF4/AF4N (AFF1) super elongation complex | Q41138339 |
| | Intermolecular recognition of the non-coding RNA 7SK and HEXIM protein in perspective. | Q41343540 |
| | Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation. | Q41853689 |
| | Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer | Q42006129 |
| | 7SK small nuclear ribonucleoprotein complex is recruited to the HIV-1 promoter via short viral transcripts | Q42232958 |
| | NEAT1-containing paraspeckles: Central hubs in stress response and tumor formation | Q42292075 |
| | Dynamic remodelling of human 7SK snRNP controls the nuclear level of active P-TEFb | Q42414886 |
| | The transcription-dependent dissociation of P-TEFb-HEXIM1-7SK RNA relies upon formation of hnRNP-7SK RNA complexes | Q42910421 |
| | Interplay between 7SK snRNA and oppositely charged regions in HEXIM1 direct the inhibition of P-TEFb | Q43192544 |
| | Evolution of 7SK RNA and its protein partners in metazoa | Q45220336 |
| | Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA. | Q46675052 |
| | 7SK small nuclear RNA, a multifunctional transcriptional regulatory RNA with gene-specific features. | Q47935959 |
| | P-TEFb: Finding its ways to release promoter-proximally paused RNA polymerase II. | Q48335211 |
| | BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment. | Q50547887 |
| | HEXIM1: a new player in myocardial hypertrophy? | Q50951210 |
| | Transcriptional pause release is a rate-limiting step for somatic cell reprogramming. | Q51691041 |
| | Vascular endothelial growth factor gene regulation by HEXIM1 in heart. | Q51963031 |
| | A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1. | Q54688294 |
| | Serine-7 but not serine-5 phosphorylation primes RNA polymerase II CTD for P-TEFb recognition | Q61207379 |
| | A hexIM1 on your melanocytes: transcription elongation - the Achilles’ heel of melanoma? | Q63407156 |
| | The crystal structure of the 5΄ functional domain of the transcription riboregulator 7SK. | Q33557347 |
| | Reconstitution of a functional 7SK snRNP | Q33878635 |
| | HEXIM1 modulates vascular endothelial growth factor expression and function in breast epithelial cells and mammary gland. | Q33940674 |
| | Genetic analysis of the structure and function of 7SK small nuclear ribonucleoprotein (snRNP) in cells | Q33947277 |
| | CLP-1 associates with MyoD and HDAC to restore skeletal muscle cell regeneration | Q34240810 |
| | HEXIM1-binding elements on mRNAs identified through transcriptomic SELEX and computational screening | Q34275119 |
| | HEXIM1 targets a repeated GAUC motif in the riboregulator of transcription 7SK and promotes base pair rearrangements | Q34368113 |
| | A Cyclin T1 point mutation that abolishes positive transcription elongation factor (P-TEFb) binding to Hexim1 and HIV tat | Q34486331 |
| | HEXIM1 is a critical determinant of the response to tamoxifen | Q35106333 |
| | T-cell receptor signaling enhances transcriptional elongation from latent HIV proviruses by activating P-TEFb through an ERK-dependent pathway | Q35113716 |
| | HEXIM1 down-regulates hypoxia-inducible factor-1α protein stability | Q35602354 |
| | A Function for the hnRNP A1/A2 Proteins in Transcription Elongation | Q35641869 |
| | Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes. | Q35668935 |
| | Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription. | Q35804608 |
| | Phosphorylation of HEXIM1 at Tyr271 and Tyr274 Promotes Release of P-TEFb from the 7SK snRNP Complex and Enhances Proviral HIV Gene Expression | Q35805406 |
| | HEXIM1 is a promiscuous double-stranded RNA-binding protein and interacts with RNAs in addition to 7SK in cultured cells. | Q35829330 |
| | Inhibition of HIV-1 replication by P-TEFb inhibitors DRB, seliciclib and flavopiridol correlates with release of free P-TEFb from the large, inactive form of the complex | Q35940053 |
| | Functional Interaction between HEXIM and Hedgehog Signaling during Drosophila Wing Development | Q36017203 |
| | PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation. | Q36174095 |
| | PKC phosphorylates HEXIM1 and regulates P-TEFb activity. | Q36305691 |
| | BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones | Q36485411 |
| | PP2B and PP1alpha cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling | Q36649160 |
| | Functional interplay between PPM1G and the transcription elongation machinery | Q36794841 |
| | Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. | Q36811094 |
| | HEXIM1 and the control of transcription elongation: from cancer and inflammation to AIDS and cardiac hypertrophy. | Q36900042 |
| | SIRT2 directs the replication stress response through CDK9 deacetylation. | Q37103812 |
| | 7SKiing on chromatin: Move globally, act locally | Q37130418 |
| | Transcription elongation control by the 7SK snRNP complex: Releasing the pause. | Q37194356 |
| | HEXIM1, a New Player in the p53 Pathway | Q37226490 |
| | U30 of 7SK RNA forms a specific photo-cross-link with Hexim1 in the context of both a minimal RNA-binding site and a fully reconstituted 7SK/Hexim1/P-TEFb ribonucleoprotein complex | Q37368093 |
| | An evolutionary conserved Hexim1 peptide binds to the Cdk9 catalytic site to inhibit P-TEFb | Q37417931 |
| | Pivotal role of cardiac lineage protein-1 (CLP-1) in transcriptional elongation factor P-TEFb complex formation in cardiac hypertrophy | Q37422875 |
| | Brd4 and HEXIM1: multiple roles in P-TEFb regulation and cancer | Q37586824 |
| | Release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein (snRNP) activates hexamethylene bisacetamide-inducible protein (HEXIM1) transcription. | Q37683410 |
| P433 | issue | 4 | |
| P304 | page(s) | 262-271 | |
| P577 | publication date | 2018-02-23 | |
| P1433 | published in | Transcription | Q25203627 |
| P1476 | title | Hexim1, an RNA-controlled protein hub | |
| P478 | volume | 9 | |