| scholarly article | Q13442814 |
| P50 | author | Guy Salvesen | Q5622580 |
| P2093 | author name string | E S Alnemri | |
| J Yuan | |||
| W W Wong | |||
| D W Nicholson | |||
| N A Thornberry | |||
| D J Livingston | |||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 171 | |
| P577 | publication date | 1996-10-18 | |
| P1433 | published in | Cell | Q655814 |
| P1476 | title | Human ICE/CED-3 protease nomenclature | |
| P478 | volume | 87 |
| Q36380492 | A CASP-8 mutation recognized by cytolytic T lymphocytes on a human head and neck carcinoma. |
| Q48389094 | A caspase inhibitor blocks ischaemia-induced delayed neuronal death in the gerbil |
| Q24681821 | A cloning method for caspase substrates that uses the yeast two-hybrid system: cloning of the antiapoptotic gene gelsolin |
| Q30654905 | A cloning method to identify caspases and their regulators in yeast: identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1. |
| Q29617776 | A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis |
| Q27739379 | A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE) |
| Q33955906 | A comprehensive characterization of the caspase gene family in insects from the order Lepidoptera. |
| Q35591686 | A decade of caspases |
| Q52190233 | A developmental timer that regulates apoptosis at the onset of gastrulation. |
| Q54789907 | A method utilizing differential culture and comparative RT-PCR for determining RNA expression in superior cervical ganglion neurones. |
| Q48093576 | A molecular basis of cell death in olfactory epithelium |
| Q43578367 | A novel apoptotic interaction between HSV-1 and human corneal epithelial cells. |
| Q41558626 | A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe |
| Q36764540 | A novel polyamine analog inhibits growth and induces apoptosis in human breast cancer cells. |
| Q36894793 | A purine nucleoside phosphorylase (PNP) inhibitor induces apoptosis via caspase-3-like protease activity in MOLT-4 T cells |
| Q39210557 | A recombined protein (rSj16) derived from Schistosoma japonicum induces cell cycle arrest and apoptosis of murine myeloid leukemia cells |
| Q35354864 | A review of the mammalian unfolded protein response. |
| Q42796163 | A role for caspases in lens fiber differentiation |
| Q34610288 | A screen for dominant modifiers of the irreC-rst cell death phenotype in the developing Drosophila retina |
| Q26744127 | A systematic review of association studies of common variants associated with idiopathic congenital talipes equinovarus (ICTEV) in humans in the past 30 years |
| Q38357755 | A yeast-based growth assay for the analysis of site-specific proteases |
| Q24534958 | A-kinase-anchoring protein 95 functions as a potential carrier for the nuclear translocation of active caspase 3 through an enzyme-substrate-like association |
| Q24310176 | ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases |
| Q34247072 | ARK5 suppresses the cell death induced by nutrient starvation and death receptors via inhibition of caspase 8 activation, but not by chemotherapeutic agents or UV irradiation |
| Q36781175 | Ablation of the transcription factors E2F1-2 limits neuroinflammation and associated neurological deficits after contusive spinal cord injury |
| Q48257720 | Absence of the frequently reported PIK3CA, CASP8, and NOTCH1 mutations in South Indian oral cancers |
| Q40732842 | Acetaminophen induces a caspase-dependent and Bcl-XL sensitive apoptosis in human hepatoma cells and lymphocytes. |
| Q32063642 | Actin cytoskeleton reorganization of the apoptotic nurse cells during the late developmental stages of oogenesis in Dacus oleae |
| Q48455875 | Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia. |
| Q48628367 | Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury. |
| Q58290217 | Activation of Multiple Interleukin-1β Converting Enzyme Homologues in Cytosol and Nuclei of HL-60 Cells during Etoposide-induced Apoptosis |
| Q40399489 | Activation of NF-kappaB following detachment delays apoptosis in intestinal epithelial cells |
| Q36605145 | Activation of a caspase 3-related cysteine protease is required for glutamate-mediated apoptosis of cultured cerebellar granule neurons |
| Q33833384 | Activation of apoptosis and its inhibition |
| Q81478294 | Activation of caspase 3, 9, 12, and Bax in masseter muscle of mdx mice during necrosis |
| Q38524833 | Activation of caspase cascades in Korean mistletoe (Viscum album var. coloratum) lectin-II-induced apoptosis of human myeloleukemic U937 cells |
| Q77998363 | Activation of caspase-3 in axotomized rat retinal ganglion cells in vivo |
| Q48174992 | Activation of caspase-3 in developmental models of programmed cell death in neurons of the substantia nigra |
| Q74155804 | Activation of caspase-3 protease via a Bcl-2-insensitive pathway during the process of ginsenoside Rh2-induced apoptosis |
| Q42992854 | Activation of caspase-3-like proteases in apoptosis induced by sphingosine and other long-chain bases in Hep3B hepatoma cells |
| Q55261427 | Activation of caspases in p53-induced transactivation-independent apoptosis. |
| Q33782567 | Activation of caspases in pig kidney cells infected with wild-type and CrmA/SPI-2 mutants of cowpox and rabbitpox viruses |
| Q74582962 | Activation of caspases triggered by cytochrome c in vitro |
| Q34328223 | Activation of caspases-8 and -10 by FLIP(L). |
| Q36630520 | Activation of distinct caspase-like proteases by Fas and reaper in Drosophila cells |
| Q40966000 | Activation of membrane-associated procaspase-3 is regulated by Bcl-2. |
| Q41779335 | Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity |
| Q37149524 | Activation of sterol regulatory element-binding protein by the caspase Drice in Drosophila larvae |
| Q36571893 | Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis |
| Q34282369 | Activation-induced cell death |
| Q47608162 | Active site-adjacent phosphorylation at Tyr-397 by c-Abl kinase inactivates caspase-9. |
| Q28576773 | Activity and expression of different members of the caspase family in the rat corpus luteum during pregnancy and postpartum |
| Q77068044 | Acyl dipeptides as reversible caspase inhibitors. Part 1: initial lead optimization |
| Q77068050 | Acyl dipeptides as reversible caspase inhibitors. Part 2: further optimization |
| Q35756912 | Additive effects of TRAIL and paclitaxel on cancer cells: implications for advances in cancer therapy. |
| Q35549014 | African flora has the potential to fight multidrug resistance of cancer |
| Q39610082 | African swine fever virus IAP homologue inhibits caspase activation and promotes cell survival in mammalian cells. |
| Q84530229 | Aged Beagle dogs have decreased neutrophil phagocytosis and neutrophil-related gene expression compared to younger dogs |
| Q33995467 | Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line |
| Q37188600 | Aldehyde dehydrogenase-2 transgene ameliorates chronic alcohol ingestion-induced apoptosis in cerebral cortex |
| Q27681042 | Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization |
| Q41051046 | Alphaviruses induce apoptosis in Bcl-2-overexpressing cells: evidence for a caspase-mediated, proteolytic inactivation of Bcl-2. |
| Q44374034 | Ammonia prevents glutamate-induced but not low K(+)-induced apoptosis in cerebellar neurons in culture |
| Q38858686 | An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death. |
| Q39761573 | An Immunomodulatory Protein (Ling Zhi-8) from a Ganoderma lucidum Induced Acceleration of Wound Healing in Rat Liver Tissues after Monopolar Electrosurgery |
| Q28354314 | An NO derivative of ursodeoxycholic acid protects against Fas-mediated liver injury by inhibiting caspase activity |
| Q46841305 | An aqueous extract from Moringa oleifera leaves ameliorates hepatotoxicity in alloxan-induced diabetic rats |
| Q33542573 | Analysis of apoptosis by laser scanning cytometry |
| Q35085204 | Analysis of in vivo role of alpha-fodrin autoantigen in primary Sjogren's syndrome |
| Q40896666 | Analysis of mechanisms involved in the prevention of gamma irradiation-induced apoptosis by hGM-CSF. |
| Q52166476 | Analysis of programmed cell death in the nematode Caenorhabditis elegans. |
| Q74261268 | Angiotensin-converting enzyme inhibitor captopril prevents activation-induced apoptosis by interfering with T cell activation signals |
| Q44954792 | Anti-angiogenic effects of thalidomide: expression of apoptosis-inducible active-caspase-3 in a three-dimensional collagen gel culture of aorta |
| Q49437869 | Anti-apoptotic potential of several antidiabetic medicinal plants of the eastern James Bay Cree pharmacopeia in cultured kidney cells. |
| Q41688099 | Anti-cancer activity of targeted pro-apoptotic peptides |
| Q33547796 | Anti-viral strategies of cytotoxic T lymphocytes are manifested through a variety of granule-bound pathways of apoptosis induction |
| Q38490702 | Anticancer effect of photodynamic therapy with hexenyl ester of 5-aminolevulinic acid in oral squamous cell carcinoma |
| Q44071251 | Anticancer-drug-induced apoptotic cell death in leukemia cells is associated with proteolysis of beta-catenin |
| Q77416578 | Antioxidant defenses in the TNF-treated MCF-7 cells: selective increase in MnSOD |
| Q59416716 | Antioxidant-mediated inhibition of the heat shock response leads to apoptosis |
| Q42827170 | Apaf-1 localization is modulated indirectly by Bcl-2 expression. |
| Q24324482 | Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3 |
| Q34312459 | Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced apoptosis in multiple myeloma |
| Q28732502 | Apoptosis and beyond: cytometry in studies of programmed cell death |
| Q33610847 | Apoptosis and its clinical significance for bladder cancer therapy |
| Q40827018 | Apoptosis and its role in the myelodysplastic syndromes: implications for disease natural history and treatment |
| Q35117847 | Apoptosis and necrosis in health and disease: Role of mitochondria |
| Q31858456 | Apoptosis associated with esophageal adenocarcinoma: influence of photodynamic therapy |
| Q28304002 | Apoptosis by death factor |
| Q36707752 | Apoptosis during herpes simplex virus infection |
| Q44865350 | Apoptosis generates stable fragments of human type I keratins |
| Q41042759 | Apoptosis in cell culture |
| Q33181854 | Apoptosis in cultured hNT neurons. |
| Q30952714 | Apoptosis in glioma cells: review and analysis of techniques used for study with focus on the laser scanning cytometer |
| Q35043424 | Apoptosis in myocardial infarction |
| Q74170837 | Apoptosis in neural development and disease |
| Q44063746 | Apoptosis in the malaria protozoan, Plasmodium berghei: a possible mechanism for limiting intensity of infection in the mosquito |
| Q48922993 | Apoptosis in ultrasound-produced threshold lesions in the rabbit brain. |
| Q47683889 | Apoptosis induction by the glucocorticoid hormone dexamethasone and the calcium-ATPase inhibitor thapsigargin involves Bc1-2 regulated caspase activation |
| Q41065117 | Apoptosis of endothelial cells is associated with paracrine induction of adhesion molecules: evidence for an interleukin-1beta-dependent paracrine loop |
| Q39214839 | Apoptosis of pancreatic β-cells in Type 1 diabetes |
| Q38322916 | Apoptosis promotes a caspase-induced amino-terminal truncation of IkappaBalpha that functions as a stable inhibitor of NF-kappaB. |
| Q34395580 | Apoptosis regulators and their role in tumorigenesis |
| Q42162973 | Apoptosis resistance in tumor cells |
| Q34407201 | Apoptosis stalks Plasmodium falciparum maintained in continuous culture condition |
| Q34404626 | Apoptosis, Part I: Biochemical assessment |
| Q34060908 | Apoptosis, cell adhesion and the extracellular matrix in the three-dimensional growth of multicellular tumor spheroids |
| Q24523640 | Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells |
| Q40957226 | Apoptosis-associated cleavage of beta-catenin in human colon cancer and rat hepatoma cells |
| Q48950370 | Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction. |
| Q40889527 | Apoptosis-induced cleavage of beta-catenin by caspase-3 results in proteolytic fragments with reduced transactivation potential |
| Q40635002 | Apoptosis-inducing effect of recombinant Caspase-3 expressed by constructed eukaryotic vector on gastric cancer cell line SGC7901. |
| Q80818125 | Apoptosis: alive and kicking in 1997 |
| Q33777704 | Apoptosis: definition, mechanisms, and relevance to disease |
| Q37902996 | Apoptosis: why and how does it occur in biology? |
| Q40644112 | Apoptosome-independent pathway for apoptosis. Biochemical analysis of APAF-1 defects and biological outcomes |
| Q48149094 | Apoptotic cell death and caspase-3 activation induced by N-methyl-D-aspartate receptor antagonists and their prevention by insulin-like growth factor I. |
| Q73280956 | Apoptotic death of hair cells in mammalian vestibular sensory epithelia |
| Q89821608 | Apoptotic functions of microRNAs in pathogenesis, diagnosis, and treatment of endometriosis |
| Q33887907 | Apoptotic mechanisms in acute renal failure |
| Q37220935 | Apoptotic neuronal death following cerebral ischaemia |
| Q36368462 | Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2. |
| Q34035849 | Apoptotic threshold is lowered by p53 transactivation of caspase-6 |
| Q52184466 | Apparent caspase independence of programmed cell death in Dictyostelium. |
| Q41050541 | Apparent cleavage of poly(ADP-ribose) polymerase in non-apoptotic mouse LTA cells: an artifact of cross-reactive secondary antibody |
| Q39752566 | Are metacaspases caspases? |
| Q31081757 | Assay of caspase activation in situ combined with probing plasma membrane integrity to detect three distinct stages of apoptosis |
| Q52590107 | Assessment of IAP (inhibitor of apoptosis) proteins as predictors of response to chemotherapy in advanced non-small-cell lung cancer patients. |
| Q40602555 | Association between tuberculosis and circulating microRNA hsa-let-7b and hsa-miR-30b: A pilot study in a Chinese population |
| Q37290315 | Association of Fas/Apo1 gene promoter (-670 A/G) polymorphism in Tunisian patients with IBD. |
| Q36400294 | Association of phosphorylated serine/arginine (SR) splicing factors with the U1-small ribonucleoprotein (snRNP) autoantigen complex accompanies apoptotic cell death |
| Q48738690 | Attenuation of transient focal cerebral ischemic injury in transgenic mice expressing a mutant ICE inhibitory protein. |
| Q28275527 | Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization |
| Q81138569 | Autoantibodies to alfa-fodrin in patients with Hashimoto thyroiditis and Sjögren's syndrome: possible markers for a common secretory disorder |
| Q37436029 | Autophagy functions in programmed cell death |
| Q47862735 | Autoproteolytic activation of pro-caspases by oligomerization |
| Q28088321 | BAG3: a new player in the heart failure paradigm |
| Q35128196 | BCL-2 modifying factor (BMF) is a central regulator of anoikis in human intestinal epithelial cells |
| Q33714125 | Baculovirus inhibitors of apoptosis (IAPs) block activation of Sf-caspase-1 |
| Q40270813 | Bax inhibitor-1 protects neurons from oxygen-glucose deprivation |
| Q40444022 | Bcl-2 antiapoptotic protein mediates verotoxin II-induced cell death: possible association between bcl-2 and tissue failure by E. coli O157:H7. |
| Q33825160 | Bcl-2 family: life-or-death switch |
| Q39677382 | Bcl-2 is a negative regulator of interleukin-1beta secretion in murine macrophages in pharmacological-induced apoptosis |
| Q37633890 | Bcl-2 knockdown accelerates T cell receptor-triggered activation-induced cell death in jurkat T cells |
| Q73098824 | Beta-amyloid-induced activation of caspase-3 in primary cultures of rat neurons |
| Q41740220 | Biochemical and molecular mechanisms regulating apoptosis |
| Q48763774 | Biochemical characterization of a Caspase-3 far-red fluorescent probe for non-invasive optical imaging of neuronal apoptosis. |
| Q47693113 | Biochemical properties of human oral polymorphonuclear leukocytes |
| Q33631360 | Biological aspects of reactive nitrogen species |
| Q73783954 | Biology of acute renal failure: therapeutic implications |
| Q22010927 | Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death |
| Q39267182 | Blocking caspase-3-dependent pathway preserves hair cells from salicylate-induced apoptosis in the guinea pig cochlea |
| Q43888266 | Butyrate induces apoptosis in murine macrophages via caspase-3, but independent of autocrine synthesis of tumor necrosis factor and nitric oxide |
| Q28248524 | CASH, a novel caspase homologue with death effector domains |
| Q49086084 | CD44-positive cells are candidates for astrocyte precursor cells in developing mouse cerebellum. |
| Q41015531 | CD95 (Fas/APO-1) induces an increased phosphatidylserine synthesis that precedes its externalization during programmed cell death |
| Q77903149 | CD95(APO-1/Fas)-mediated apoptosis: live and let die |
| Q52195652 | CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9. |
| Q24310562 | CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor |
| Q34065573 | CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis |
| Q64261079 | CLIC1 promotes the progression of oral squamous cell carcinoma via integrins/ERK pathways |
| Q41636957 | Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues |
| Q33180183 | Cadmium induces caspase-mediated cell death: suppression by Bcl-2. |
| Q47068839 | Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor |
| Q37310184 | Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis |
| Q24309652 | Calcium binding of ARC mediates regulation of caspase 8 and cell death |
| Q42506474 | Calmodulin, poly(ADP-ribose)polymerase and p53 are targets for modulating the effects of sulfur mustard |
| Q44496373 | Calpain facilitates the neuron death induced by 3-nitropropionic acid and contributes to the necrotic morphology |
| Q53115335 | Cap1p attenuates the apoptosis of Candida albicans. |
| Q77896984 | Cascades of mammalian caspase activation in the yeast Saccharomyces cerevisiae |
| Q74449055 | Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21 |
| Q37308327 | Caspase 6 regulates B cell activation and differentiation into plasma cells |
| Q43832521 | Caspase 7 can cleave tumor necrosis factor receptor-I (p60) at a non-consensus motif, in vitro |
| Q77408419 | Caspase 7-induced cleavage of kinectin in apoptotic cells |
| Q40757141 | Caspase 9 is required for p53-dependent apoptosis and chemosensitivity in a human ovarian cancer cell line |
| Q40960316 | Caspase I-related protease inhibition retards the execution of okadaic acid- and camptothecin-induced apoptosis and PAI-2 cleavage, but not commitment to cell death in HL-60 cells. |
| Q42183316 | Caspase activation as a versatile assay platform for detection of cytotoxic bacterial toxins |
| Q35724208 | Caspase activation during virus infection: more than just the kiss of death? |
| Q42623004 | Caspase activity is required for commitment to Fas-mediated apoptosis. |
| Q24683768 | Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis |
| Q38290263 | Caspase cleavage product lacking amino-terminus of IkappaBalpha sensitizes resistant cells to TNF-alpha and TRAIL-induced apoptosis |
| Q35049064 | Caspase inhibitors as anti-inflammatory and antiapoptotic agents. |
| Q74752246 | Caspase proteases mediate apoptosis induced by anticancer agent preactivated MC540 in human tumor cell lines |
| Q36643570 | Caspase substrates |
| Q37040257 | Caspase substrates and inhibitors |
| Q24531784 | Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9 |
| Q34586647 | Caspase-1 as a central regulator of high fat diet-induced non-alcoholic steatohepatitis |
| Q50335883 | Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. |
| Q40269045 | Caspase-10 involvement in cytotoxic drug-induced apoptosis of tumor cells. |
| Q28287021 | Caspase-14 is a novel developmentally regulated protease |
| Q38024075 | Caspase-1: is IL-1 just the tip of the ICEberg? |
| Q28217828 | Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria |
| Q92534466 | Caspase-2 promotes AMPA receptor internalization and cognitive flexibility via mTORC2-AKT-GSK3β signaling |
| Q34808941 | Caspase-2 short isoform interacts with membrane-associated cytoskeleton proteins to inhibit apoptosis |
| Q60735418 | Caspase-3 Mediated Cell Death in the Normal Development of the Mammalian Cerebellum |
| Q34270984 | Caspase-3 apoptotic signaling following injury to the central nervous system. |
| Q40483427 | Caspase-3 drives apoptosis in pancreatic cancer cells after treatment with gemcitabine |
| Q34733236 | Caspase-3 is involved in IFN-γ- and TNF-α-mediated MIN6 cells apoptosis via NF-κB/Bcl-2 pathway |
| Q54220801 | Caspase-3 mediated cleavage of HsRad51 at an unconventional site. |
| Q77861013 | Caspase-3-dependent organ apoptosis early after burn injury |
| Q33799694 | Caspase-7 cleavage of Kaposi sarcoma-associated herpesvirus ORF57 confers a cellular function against viral lytic gene expression |
| Q39597061 | Caspase-dependent N-terminal cleavage of influenza virus nucleocapsid protein in infected cells. |
| Q34520118 | Caspase-dependent apoptotic pathways in CNS injury |
| Q54050681 | Caspase-dependent cleavage of the retinoblastoma protein is an early step in neuronal apoptosis. |
| Q34152298 | Caspase-like protease involvement in the control of plant cell death |
| Q24533217 | Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1 |
| Q28296478 | Caspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosis |
| Q77402807 | Caspase-mediated cleavage of cytoskeletal actin plays a positive role in the process of morphological apoptosis |
| Q24531676 | Caspase-mediated cleavage of eukaryotic translation initiation factor subunit 2alpha |
| Q42328751 | Caspase-mediated proteolysis of the sorting nexin 2 disrupts retromer assembly and potentiates Met/hepatocyte growth factor receptor signaling |
| Q43615316 | Caspases (interleukin-1beta-converting enzyme family proteases) are involved in the regulation of the survival of osteoclasts |
| Q33857511 | Caspases - controlling intracellular signals by protease zymogen activation |
| Q40424967 | Caspases activation in hyperthermia-induced stimulation of TRAIL apoptosis. |
| Q41633125 | Caspases and caspase inhibitors |
| Q35187214 | Caspases and neuronal development |
| Q39302531 | Caspases and their substrates |
| Q24647389 | Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis |
| Q89526718 | Caspases in Cell Death, Inflammation, and Gasdermin-Induced Pyroptosis |
| Q41671448 | Caspases induce cytochrome c release from mitochondria by activating cytosolic factors |
| Q34733021 | Caspases on the brain |
| Q36288298 | Caspases shutdown nonsense-mediated mRNA decay during apoptosis |
| Q38759273 | Caspases, Cell Death and Diabetic Nephropathy |
| Q29616315 | Caspases: killer proteases |
| Q28216089 | Caspases: opening the boxes and interpreting the arrows |
| Q24536096 | Caspases: pharmacological manipulation of cell death |
| Q24530218 | Caspases: the executioners of apoptosis |
| Q24315042 | Casper is a FADD- and caspase-related inducer of apoptosis |
| Q37152010 | Cell death in brain development and degeneration: control of caspase expression may be key! |
| Q34529394 | Cell death in the peripheral nervous system: potential rescue strategies |
| Q33717488 | Cell death induced by the Fas/Fas ligand pathway and its role in pathology |
| Q73108322 | Cell death induction by CTL: perforin/granzyme B system dominantly acts for cell death induction in human hepatocellular carcinoma cells |
| Q41554119 | Cell death induction by receptors of the TNF family: towards a molecular understanding. |
| Q24644733 | Cell death specification in C. elegans |
| Q43651285 | Cell differentiation and apoptosis of monocytic and promyelocytic leukemia cells (U-937 and HL-60) by tryptanthrin, an active ingredient of Polygonum tinctorium Lour |
| Q36768874 | Cell suicide and caspases |
| Q41075236 | Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release |
| Q38524702 | Cellular Mechanisms of Oxidative Stress and Action in Melanoma. |
| Q35553007 | Cellular and molecular themes in apoptosis |
| Q43884181 | Cellular lipid peroxidation end-products induce apoptosis in human lens epithelial cells |
| Q38111614 | Cellular mechanisms controlling caspase activation and function |
| Q33674213 | Cellular stress responses: cell survival and cell death |
| Q35207777 | Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cells |
| Q86822652 | Characterization and changes in neurotrophin receptor p75-Expressing motor neurons in SOD1(G93A) G1H mice [corrected] |
| Q52859607 | Characterization of Semaphorin 6A-Mediated Effects on Angiogenesis Through Regulation of VEGF Signaling. |
| Q73966972 | Characterization of room temperature induced apoptosis in HL-60 |
| Q36871217 | Characterization of the avian Ich-1 cDNA and expression of Ich-1L mRNA in the hen ovary |
| Q55024368 | Characterization of the caspase family in zebrafish. |
| Q48018973 | Characterization of the chicken interleukin-1beta converting enzyme (caspase-1) cDNA and expression of caspase-1 mRNA in the hen. |
| Q42796334 | Characterization of the interleukin-1beta-converting enzyme/ced-3-family protease, caspase-3/CPP32, in Hodgkin's disease: lack of caspase-3 expression in nodular lymphocyte predominance Hodgkin's disease |
| Q42157819 | Characterization of zebrafish caspase-3 and induction of apoptosis through ceramide generation in fish fathead minnow tailbud cells and zebrafish embryo |
| Q89666933 | Chlorella sorokiniana Extract Prevents Cisplatin-Induced Myelotoxicity In Vitro and In Vivo |
| Q33869177 | Cif (Cytochrome c efflux-inducing factor) activity is regulated by Bcl-2 and caspases and correlates with the activation of Bid. |
| Q90110470 | Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases |
| Q58659182 | Cleavage and relocation of the tyrosine kinase P59FYN during Fas-mediated apoptosis in T lymphocytes |
| Q47827995 | Cleavage of CDK inhibitor p21(Cip1/Waf1) by caspases is an early event during DNA damage-induced apoptosis. |
| Q28235828 | Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor |
| Q49094311 | Cleavage of caspase family members by granzyme B: a comparative study in vitro. |
| Q41737519 | Clinical effects of mutations to CD95 (Fas): relevance to autoimmunity? |
| Q42483203 | Clofilium, a potassium channel blocker, induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3. |
| Q28568764 | Cloning and expression of the cDNA encoding rat caspase-2 |
| Q39262068 | Co-culture of C2C12 and 3T3-L1 preadipocyte cells alters the gene expression of calpains, caspases and heat shock proteins |
| Q73704701 | Co-localization of active caspase-3 and DNA fragmentation (TUNEL) in normal and hyperthermia-induced abnormal mouse development |
| Q28578435 | Cocaine exposure in vitro induces apoptosis in fetal locus coeruleus neurons by altering the Bax/Bcl-2 ratio and through caspase-3 apoptotic signaling |
| Q43124126 | Colchicine-induced apoptosis was prevented by glycogen synthase kinase-3 inhibitors in PC12 cells |
| Q37042617 | Combination treatment with flavonoid morin and telomerase inhibitor MST‑312 reduces cancer stem cell traits by targeting STAT3 and telomerase |
| Q64107893 | Combined effects of XAF1 and TRAIL on the apoptosis of lung adenocarcinoma cells |
| Q33786573 | Commitment and effector phases of the physiological cell death pathway elucidated with respect to Bcl-2 caspase, and cyclin-dependent kinase activities |
| Q40952877 | Comparison of paclitaxel-, 5-fluoro-2'-deoxyuridine-, and epidermal growth factor (EGF)-induced apoptosis. Evidence for EGF-induced anoikis |
| Q77749492 | Conformationally constrained inhibitors of caspase-1 (interleukin-1 beta converting enzyme) and of the human CED-3 homologue caspase-3 (CPP32, apopain) |
| Q22008521 | Construction of an approximately 700-kb transcript map around the familial Mediterranean fever locus on human chromosome 16p13.3 |
| Q47966880 | Contribution of the ICE family to neurodegeneration |
| Q26776532 | Converging roles of caspases in inflammasome activation, cell death and innate immunity |
| Q37203389 | Converting enzyme-independent release of tumor necrosis factor alpha and IL-1beta from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3 |
| Q37690296 | Cooperative interaction of trp melastatin channel transient receptor potential (TRPM2) with its splice variant TRPM2 short variant is essential for endothelial cell apoptosis |
| Q40891022 | Correlation between structure of Bcl-2 and its inhibitory function of JNK and caspase activity in dopaminergic neuronal apoptosis |
| Q40793113 | Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation |
| Q24293643 | Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78 |
| Q83142879 | Coxsackievirus protein 2BC blocks host cell apoptosis by inhibiting caspase-3 |
| Q45864989 | CrmA gene expression protects mice against concanavalin-A-induced hepatitis by inhibiting IL-18 secretion and hepatocyte apoptosis |
| Q27653310 | Crystal Structure of Procaspase-1 Zymogen Domain Reveals Insight into Inflammatory Caspase Autoactivation |
| Q27642657 | Crystal structure of an invertebrate caspase |
| Q36594908 | Current concepts in apoptosis: the physiological suicide program revisited. |
| Q36071638 | Current progress of siRNA/shRNA therapeutics in clinical trials |
| Q54313407 | Cyanobacteria-blooming water samples from Lake Taihu induce endoplasmic reticulum stress in liver and kidney of mice. |
| Q33887189 | Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system. |
| Q24311006 | Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade |
| Q45189674 | Cytometric methods to detect apoptosis |
| Q28748522 | Cytometry in cell necrobiology revisited. Recent advances and new vistas |
| Q28716677 | Cytometry of apoptosis. Historical perspective and new advances |
| Q73146601 | Cytometry of caspases |
| Q38974581 | Cytotoxic flavonoids and isoflavonoids from Erythrina sigmoidea towards multi-factorial drug resistant cancer cells. |
| Q41639712 | Cytotoxic, anti-proliferative and apoptotic effects of silver nitrate against H-ras transformed 5RP7. |
| Q36229776 | Cytotoxicity of Plumbagin, Rapanone and 12 other naturally occurring Quinones from Kenyan Flora towards human carcinoma cells |
| Q38859679 | Cytotoxicity of anthraquinones from the roots of Pentas schimperi towards multi-factorial drug-resistant cancer cells |
| Q35095042 | Cytotoxicity of cyclometalated platinum complexes based on tridentate NCN and CNN-coordinating ligands: remarkable coordination dependence |
| Q35273073 | Cytotoxicity of polyaniline nanomaterial on rat celiac macrophages in vitro |
| Q47706678 | Cytotoxicity of seputhecarpan D, thonningiol and 12 other phytochemicals from African flora towards human carcinoma cells |
| Q33643485 | Cytotoxicity, mode of action and antibacterial activities of selected Saudi Arabian medicinal plants |
| Q38455317 | D-amino acid based protein arginine deiminase inhibitors: Synthesis, pharmacokinetics, and in cellulo efficacy |
| Q24313625 | DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis |
| Q28076278 | Danger signals, inflammasomes, and the intricate intracellular lives of chlamydiae |
| Q39686369 | Daphnetin inhibits TNF-α and VEGF-induced angiogenesis through inhibition of the IKKs/IκBα/NF-κB, Src/FAK/ERK1/2 and Akt signalling pathways |
| Q39745862 | Death Inducer-Obliterator 1 Triggers Apoptosis after Nuclear Translocation and Caspase Upregulation |
| Q35990527 | Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis |
| Q34537833 | Death receptors couple to both cell proliferation and apoptosis |
| Q40949947 | Death signals from the B cell antigen receptor target mitochondria, activating necrotic and apoptotic death cascades in a murine B cell line, WEHI-231. |
| Q41516491 | Death substrates come alive |
| Q48388840 | Death-signalling cascade in mouse cerebellar granule neurons |
| Q41745119 | Deciphering the apoptotic pathway: all roads lead to death |
| Q47993612 | Delayed Fas-mediated hepatocyte apoptosis during liver regeneration in mice: hepatoprotective role of TNF alpha |
| Q28253849 | Dentatorubral pallidoluysian atrophy (DRPLA) protein is cleaved by caspase-3 during apoptosis |
| Q52116032 | Deoxyribonuclease IIalpha is required during the phagocytic phase of apoptosis and its loss causes perinatal lethality. |
| Q73505723 | Dephosphorylation-induced decrease of anti-apoptotic function of Bcl-2 in neuronally differentiated P19 cells following ischemic insults |
| Q33536031 | Deregulation of apoptosis in colorectal carcinoma: theoretical and therapeutic implications |
| Q52666823 | Design, Synthesis and Docking Studies of Flavokawain B Type Chalcones and Their Cytotoxic Effects on MCF-7 and MDA-MB-231 Cell Lines. |
| Q30987525 | Detection of caspases activation by fluorochrome-labeled inhibitors: Multiparameter analysis by laser scanning cytometry |
| Q36409394 | Detection of epithelial cell death in the body by cytokeratin 18 measurement |
| Q34750366 | Determinants of resistance to 2',2'-difluorodeoxycytidine (gemcitabine). |
| Q35792081 | Development of Autoimmune Exocrinopathy Resembling Sjögren's Syndrome in Estrogen-Deficient Mice of Healthy Background |
| Q57793276 | Development of a fluorescence-based cellular apoptosis reporter |
| Q53141633 | Development of meloxicam salts with improved dissolution and pharmacokinetic behaviors in rats with impaired gastric motility. |
| Q43586550 | Dexamethasone inhibits spontaneous apoptosis in primary cultures of human and rat hepatocytes via Bcl-2 and Bcl-xL induction |
| Q37968210 | Diabetes-induced birth defects: what do we know? What can we do? |
| Q37733102 | Dietary hyperglycemia, glycemic index and metabolic retinal diseases |
| Q49162419 | Differential changes of potassium currents in CA1 pyramidal neurons after transient forebrain ischemia. |
| Q44530770 | Differential expression of YAMA/CPP-32 by T lymphocytes in popliteal artery aneurysm. |
| Q28579967 | Differential subcellular localization of caspase family proteins in the adult rat brain |
| Q50518461 | Differentiation and assessment of cell death. |
| Q39550054 | Differentiation of M1 myeloid precursor cells into macrophages results in binding and infection by Theiler's murine encephalomyelitis virus and apoptosis |
| Q52310353 | Difunctional bacteriophage conjugated with photosensitizers for Candida albicans-targeting photodynamic inactivation. |
| Q42831152 | Dimerization and autoprocessing of the Nedd2 (caspase-2) precursor requires both the prodomain and the carboxyl-terminal regions |
| Q33372560 | Discovery of a new RNA-containing nuclear structure in UVC-induced apoptotic cells by integrated laser electron microscopy |
| Q36276559 | Dismantling cell-cell contacts during apoptosis is coupled to a caspase-dependent proteolytic cleavage of beta-catenin. |
| Q47886310 | Dismantling in cell death: molecular mechanisms and relationship to caspase activation |
| Q33942658 | Distinct stages of cytochrome c release from mitochondria: evidence for a feedback amplification loop linking caspase activation to mitochondrial dysfunction in genotoxic stress induced apoptosis |
| Q49301662 | Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer. |
| Q40016052 | Disturbance of apoptosis and DNA synthesis by Helicobacter pylori infection of hepatocytes |
| Q34281577 | Divergent modulation of neuronal differentiation by caspase-2 and -9. |
| Q46376571 | Diverse apoptotic pathways in enterovirus 71-infected cells |
| Q28387136 | Does antigen masking by ubiquitin chains protect from the development of autoimmune diseases? |
| Q50542289 | Drosophila MOF regulates DIAP1 and induces apoptosis in a JNK dependent pathway. |
| Q41729429 | Dual mechanisms of apoptosis induction by cytotoxic lymphocytes. |
| Q34441395 | Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis |
| Q36771058 | Dynorphin A (1-17) induces apoptosis in striatal neurons in vitro through alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor-mediated cytochrome c release and caspase-3 activation |
| Q28273537 | ERICE, a novel FLICE-activatable caspase |
| Q24676652 | ERM (ezrin/radixin/moesin)-based molecular mechanism of microvillar breakdown at an early stage of apoptosis |
| Q39155431 | Ebselen reduces the toxicity of mechlorethamine in A-431 cells via inhibition of apoptosis |
| Q73079283 | Effect of Bcl-2 and caspase-3 on calcium distribution in apoptosis of HL-60 cells |
| Q74591044 | Effect of aged garlic extract on caspase-3 activity, in vitro |
| Q41210385 | Effect of granatin B on the glioma cancer by inducing apoptosis |
| Q42861798 | Effect of post-hypoxic reoxygenation on DNA fragmentation in cortical neuronal nuclei of newborn piglets |
| Q45269494 | Effects of spider Macrothele raven venom on cell proliferation and cytotoxicity in HeLa cells |
| Q55087142 | Elevation of cytoplasmic cytochrome c in radiation-induced apoptosis. |
| Q111199424 | Emerging Insights on Caspases in COVID-19 Pathogenesis, Sequelae, and Directed Therapies |
| Q45333413 | Emulsified isoflurane postconditioning produces cardioprotection against myocardial ischemia-reperfusion injury in rats |
| Q33816829 | Endogenous inhibitors of caspases |
| Q73614045 | Enhanced expression of caspase-3 in hypertrophic scars and keloid: induction of caspase-3 and apoptosis in keloid fibroblasts in vitro |
| Q38961773 | Enhanced in vitro antiproliferative effects of EpCAM antibody-functionalized paclitaxel-loaded PLGA nanoparticles in retinoblastoma cells |
| Q37480728 | Epigenetic regulation of caspase-3 gene expression in rat brain development |
| Q41655689 | Errors of homeostasis and deregulated apoptosis |
| Q30419902 | Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant |
| Q28506930 | Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes |
| Q37554874 | Establishment of a cell-free system of neuronal apoptosis: comparison of premitochondrial, mitochondrial, and postmitochondrial phases |
| Q44326389 | Ethanol promotes T cell apoptosis through the mitochondrial pathway. |
| Q35228629 | Ethyl acetate extract from marine sponge Hyattella cribriformis exhibit potent anticancer activity by promoting tubulin polymerization as evidenced mitotic arrest and induction of apoptosis |
| Q39577003 | Eukaryotic translation initiation factor 4G is targeted for proteolytic cleavage by caspase 3 during inhibition of translation in apoptotic cells |
| Q43733593 | Eupatilin, a pharmacologically active flavone derived from Artemisia plants, induces apoptosis in human promyelocytic leukemia cells |
| Q36868111 | Evaluation of Arsenic Trioxide Potential for Lung Cancer Treatment: Assessment of Apoptotic Mechanisms and Oxidative Damage |
| Q34693245 | Evaluation of caspase activity in apoptotic cells |
| Q98458087 | Evaluation of caspase-3 activity during apoptosis with fluorescence lifetime-based cytometry measurements and phasor analyses |
| Q28539112 | Evaluation of schistosome promoter expression for transgenesis and genetic analysis |
| Q42501016 | Evidence for redox regulation of cytochrome C release during programmed neuronal death: antioxidant effects of protein synthesis and caspase inhibition. |
| Q35186914 | Evidence of the involvement of caspase-1 under physiologic and pathologic cellular stress during human pregnancy: a link between the inflammasome and parturition |
| Q43570184 | Evidence that Fas-induced apoptosis leads to S phase arrest |
| Q44412165 | Evodiamine, a constituent of Evodiae Fructus, induces anti‐proliferating effects in tumor cells |
| Q37661239 | Executioners of apoptosis in pancreatic {beta}-cells: not just for cell death |
| Q40439065 | Exploration of intrinsic and extrinsic apoptotic pathways in zearalenone-treated rat sertoli cells |
| Q73462071 | Expression and activity of caspases 1 and 3 in myelodysplastic syndromes |
| Q52609401 | Expression of Drosophila Ca2+ permeable transient receptor potential-like channel protein in a prostate cancer cell line decreases cell survival. |
| Q53615179 | Expression of IL-1beta, IL-1 receptor type I and IL-1 receptor antagonist in human aortic smooth muscle cells: effects of all-trans-retinoic acid. |
| Q36619676 | Expression of caspases 3, 6 and 8 is increased in parallel with apoptosis and histological aggressiveness of the breast lesion |
| Q35786883 | Expression of cytotoxic proteins by neoplastic T cells in mycosis fungoides increases with progression from plaque stage to tumor stage disease |
| Q44249688 | Expression of dominant-negative Fas-associated death domain blocks human keratinocyte apoptosis and vesication induced by sulfur mustard |
| Q46153879 | Extracellular adenosine induces apoptosis in Caco-2 human colonic cancer cells by activating caspase-9/-3 via A(2a) adenosine receptors |
| Q28244048 | FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis |
| Q41509941 | Facing death in the fly: genetic analysis of apoptosis in Drosophila |
| Q71840940 | Fas ligand and immune evasion |
| Q28304324 | Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling |
| Q47762721 | Fas-induced DNA fragmentation and proteolysis of nuclear proteins |
| Q36654745 | Fas-induced apoptosis of T cells occurs independently of ceramide generation |
| Q41035852 | Fas-mediated apoptosis in mouse hepatocytes involves the processing and activation of caspases |
| Q77693534 | Fas-mediated apoptosis of hepatic cells |
| Q38094830 | Flow cytometry based assays for the measurement of apoptosis-associated mitochondrial membrane depolarisation and cytochrome c release |
| Q34223173 | Flow cytometry in analysis of cell cycle and apoptosis |
| Q36989962 | Forced involution of the functionally differentiated mammary gland by overexpression of the pro-apoptotic protein bax |
| Q34098735 | Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1. |
| Q34068970 | From bench to clinic with apoptosis-based therapeutic agents |
| Q41109952 | Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis |
| Q42751498 | Functional analysis of tumour necrosis factor-alpha-related apoptosis-inducing ligand (TRAIL): cysteine-230 plays a critical role in the homotrimerization and biological activity of this novel tumoricidal cytokine |
| Q34370867 | Functional decline in aging and disease: a role for apoptosis |
| Q38214149 | Functions of caspase 8: the identified and the mysterious |
| Q34580284 | G Protein signaling modulator-3 inhibits the inflammasome activity of NLRP3 |
| Q36824282 | Gene expression profiling of the anti-glioma effect of Cilengitide |
| Q21092779 | Gene losses during human origins |
| Q33713375 | Gene targeting in the analysis of mammalian apoptosis and TNF receptor superfamily signaling |
| Q34279589 | Generation and characterization of Smac/DIABLO-deficient mice. |
| Q41039427 | Generation of constitutively active recombinant caspases-3 and -6 by rearrangement of their subunits |
| Q40977188 | Generation of hydrogen peroxide precedes loss of mitochondrial membrane potential during DNA alkylation-induced apoptosis |
| Q38308797 | Genetic analysis of oral squamous cell carcinoma by cDNA microarrays focused apoptotic pathway. |
| Q37179339 | Genetic characterization of two gain-of-function alleles of the effector caspase DrICE in Drosophila |
| Q41604606 | Genetic control of programmed cell death and aging in the nematode Caenorhabditis elegans. |
| Q34060217 | Genetic regulation of programmed cell death in Drosophila |
| Q40835187 | Genetics of programmed cell death in C. elegans: past, present and future. |
| Q42451967 | Gingival and dermal fibroblasts produce interleukin‐1β converting enzyme and interleukin‐1β but not interleukin‐18 even after stimulation with lipopolysaccharide |
| Q54472406 | Ginkgo biloba extract reducing myocardium cells apoptosis by regulating apoptotic related proteins expression in myocardium tissues. |
| Q34390540 | Global metabolic profiling of infection by an oncogenic virus: KSHV induces and requires lipogenesis for survival of latent infection |
| Q48152048 | Gold nanoparticles-conjugated quercetin induces apoptosis via inhibition of EGFR/PI3K/Akt-mediated pathway in breast cancer cell lines (MCF-7 and MDA-MB-231). |
| Q55209440 | Granulocyte Colony-Stimulating Factor Alleviates Bacterial-Induced Neuronal Apoptotic Damage in the Neonatal Rat Brain through Epigenetic Histone Modification. |
| Q41094805 | Granulocytic differentiation of HL-60 cells results in spontaneous apoptosis mediated by increased caspase expression |
| Q31911825 | Griseofulvin potentiates antitumorigenesis effects of nocodazole through induction of apoptosis and G2/M cell cycle arrest in human colorectal cancer cells |
| Q48216448 | Group I metabotropic receptors down-regulate nitric oxide induced caspase-3 activity in rat hippocampal neurons |
| Q28208528 | HIV-1 Vpr induces apoptosis through caspase 9 in T cells and peripheral blood mononuclear cells |
| Q28363800 | HIV-1 coat protein gp120 stimulates interleukin-1beta secretion from human neuroblastoma cells: evidence for a role in the mechanism of cell death |
| Q40067650 | HPV+ cervical carcinomas and cell lines display altered expression of caspases |
| Q38503815 | Haeamtang induces apoptosis of colon cancer HT-29 cells through activation of caspase-3. |
| Q27677281 | Helical Repeat Structure of Apoptosis Inhibitor 5 Reveals Protein-Protein Interaction Modules |
| Q36375454 | Herpes simplex virus type 1 infection of activated cytotoxic T cells: Induction of fratricide as a mechanism of viral immune evasion |
| Q46902175 | Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms |
| Q45722721 | High-neurovirulence GDVII virus induces apoptosis in murine astrocytes through tumor necrosis factor (TNF)-receptor and TNF-related apoptosis-inducing ligand |
| Q34117471 | Hijacking of apoptotic pathwaysby bacterial pathogens |
| Q38217666 | Histone deacetylase inhibitors and cell death |
| Q34470432 | Homologous p35 proteins of baculoviruses show distinctive anti-apoptotic activities which correlate with the apoptosis-inducing activity of each virus |
| Q40887176 | Hormonal regulation of apoptosis an ovarian perspective |
| Q34931816 | How death shapes life during development |
| Q39061320 | Hsa-let-7g miRNA targets caspase-3 and inhibits the apoptosis induced by ox-LDL in endothelial cells |
| Q40881102 | Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3. |
| Q35129790 | Hsp27 protects mitochondria of thermotolerant cells against apoptotic stimuli |
| Q33716832 | Hsp70 mutant proteins modulate additional apoptotic pathways and improve cell survival |
| Q34428120 | Hsp90 is involved in apoptosis of Candida albicans by regulating the calcineurin-caspase apoptotic pathway |
| Q24533921 | Human IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome c |
| Q24299228 | Human caspase 12 has acquired deleterious mutations |
| Q34608215 | Human caspases: activation, specificity, and regulation |
| Q24670396 | Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family |
| Q48468315 | Huperzine A ameliorates cognitive deficits and oxidative stress in the hippocampus of rats exposed to acute hypobaric hypoxia. |
| Q38525125 | Hwansodan protects PC12 cells against serum-deprivation-induced apoptosis via a mechanism involving Ras and mitogen-activated protein (MAP) kinase pathway |
| Q39733379 | Hydrocinchonine, cinchonine, and quinidine potentiate paclitaxel-induced cytotoxicity and apoptosis via multidrug resistance reversal in MES-SA/DX5 uterine sarcoma cells |
| Q34269672 | Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits. |
| Q33207008 | Hydrostatic pressure induces apoptosis in the human leukaemic T-cell line Jurkat via the mitochondrial pathway |
| Q40762635 | Hypericin and hypocrellin induced apoptosis in human mucosal carcinoma cells |
| Q36893284 | Hypertrophic cardiomyopathy in high-fat diet-induced obesity: role of suppression of forkhead transcription factor and atrophy gene transcription |
| Q24804177 | Hypoxia-mediated apoptosis in oral carcinoma cells occurs via two independent pathways |
| Q41065646 | ICE-like protease (caspase) is involved in transforming growth factor beta1-mediated apoptosis in FaO rat hepatoma cell line |
| Q73978686 | IGF-I receptor activation and BCL-2 overexpression prevent early apoptotic events in human neuroblastoma |
| Q52889697 | IL-4 administration exerts preventive effects via suppression of underlying inflammation and TNF-α-induced apoptosis in steroid-induced osteonecrosis. |
| Q40800593 | Identification and analysis of caspase substrates: proteolytic cleavage of poly(ADP-ribose)polymerase and DNA fragmentation factor 45. |
| Q28250747 | Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL |
| Q28117928 | Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins |
| Q29999194 | Identification of caspases that cleave presenilin-1 and presenilin-2 |
| Q43531090 | Identification of multiple Caenorhabditis elegans caspases and their potential roles in proteolytic cascades |
| Q34049364 | Identification of the novel substrates for caspase-6 in apoptosis using proteomic approaches |
| Q41960264 | Identification of the regulatory autophosphorylation site of autophosphorylation-dependent protein kinase (auto-kinase). Evidence that auto-kinase belongs to a member of the p21-activated kinase family |
| Q48358001 | Immunoblot analyses of the relative contributions of cysteine and aspartic proteases to neurofilament breakdown products following experimental brain injury in rats |
| Q30679878 | Immunocytochemical detection of leukocyte-associated and apoptosis-related antigen expression in childhood brain tumors |
| Q35183072 | Immunoelectron microscopic and biochemical studies of caspase-cleaved tau in a mouse model of tauopathy |
| Q79255060 | Immunohistochemical evaluation of cell proliferation antigen Ki-67 and apoptosis-related proteins Bcl-2 and caspase-3 in oral granular cell tumor |
| Q41737512 | Immunopathology of apoptosis--introduction and overview. |
| Q54560975 | Impaired apoptotic death signaling in inflammatory lung neutrophils is associated with decreased expression of interleukin-1 beta converting enzyme family proteases (caspases). |
| Q33935231 | Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates |
| Q36246481 | Implication of different domains of the Leishmania major metacaspase in cell death and autophagy |
| Q47631854 | In Vivo-Near Infrared Imaging of Neurodegeneration |
| Q33184357 | In situ activation of caspases and serine proteases during apoptosis detected by affinity labeling their enzyme active centers with fluorochrome-tagged inhibitors |
| Q74064153 | In vitro assays for caspase-3 activation and DNA fragmentation |
| Q44942517 | In vitro determination of the apoptotic effect of heparin on lymphoblasts using DNA analysis and measurements of Fas and Bcl-2 proteins by flow cytometry |
| Q35165630 | In vivo CaspaseTracker biosensor system for detecting anastasis and non-apoptotic caspase activity |
| Q60010618 | In vivo study of motoneuron death induced by nerve injury in mice deficient in the caspase 1/ interleukin-1β-converting enzyme |
| Q33781560 | Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis |
| Q28580707 | Inactivation of farnesyltransferase and geranylgeranyltransferase I by caspase-3: cleavage of the common alpha subunit during apoptosis |
| Q83972852 | Increased expression of calcium-sensing receptors in atherosclerosis confers hypersensitivity to acute myocardial infarction in rats |
| Q52541928 | Increased mitochondrial cytochrome c levels and mitochondrial hyperpolarization precede camptothecin-induced apoptosis in Jurkat cells. |
| Q51025137 | Induced phenotype targeted therapy: radiation-induced apoptosis-targeted chemotherapy. |
| Q33825495 | Induction and prevention of apoptosis in human HEp-2 cells by herpes simplex virus type 1. |
| Q35951814 | Induction of allergic inflammation by interleukin-18 in experimental animal models |
| Q40540682 | Induction of antiproliferative effect by diosgenin through activation of p53, release of apoptosis-inducing factor (AIF) and modulation of caspase-3 activity in different human cancer cells. |
| Q104667314 | Induction of apoptosis by cryptophycin 1, a new antimicrotubule agent |
| Q28372886 | Induction of apoptosis by dexrazoxane (ICRF-187) through caspases in the absence of c-jun expression and c-Jun NH2-terminal kinase 1 (JNK1) activation in VM-26-resistant CEM cells |
| Q40722126 | Induction of apoptosis by the new anticancer drug XK469 in human ovarian cancer cell lines |
| Q40204272 | Induction of apoptosis in human tumor cells after exposure to Auger electrons: comparison with gamma-ray exposure |
| Q38524410 | Induction of apoptotic cell death by a p53-independent pathway in neuronal SK-N-MC cells after treatment with 2,2',5,5'-tetrachlorobiphenyl |
| Q47949461 | Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia. |
| Q40744342 | Induction of cytochrome c-mediated apoptosis by amyloid beta 25-35 requires functional mitochondria |
| Q41071828 | Induction of interleukin-1 beta-converting enzyme (ICE) in murine microglia by lipopolysaccharide |
| Q43991411 | Induction of microsomal epoxide hydrolase by sulfur amino acid deprivation via the pathway of C-Jun N-terminal kinase and its extracellular exposure during cell death |
| Q74481271 | Induction of the mitochondrial permeability transition causes release of the apoptogenic factor cytochrome c |
| Q53407740 | Inductions of fibroblast-like morphology and high growth activity by low-dose CPT-11 in PC12 cells: role of tenascin. |
| Q47368616 | Inflammasomes, the eye and anti-inflammasome therapy. |
| Q28263855 | Inflammatory caspases and inflammasomes: master switches of inflammation |
| Q22010404 | Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II |
| Q48009496 | Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in vivo. |
| Q47721535 | Inhibition of TNF-induced apoptosis by NF-kappa B. |
| Q33890314 | Inhibition of apoptosis and clonogenic survival of cells expressing crmA variants: optimal caspase substrates are not necessarily optimal inhibitors |
| Q36641395 | Inhibition of apoptosis in human tumour cells by the tumour-associated serpin, SCC antigen-1. |
| Q28114818 | Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease |
| Q43715259 | Inhibition of caspase-3-like activity reduces glutamate induced cell death in adult rat retina. |
| Q55259082 | Inhibition of cyclin D1 expression and induction of apoptosis by inostamycin in small cell lung carcinoma cells. |
| Q50526824 | Inhibition of etoposide-induced apoptotic events by azide. |
| Q36030783 | Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage |
| Q41671823 | Inhibition of interleukin-1beta converting enzyme family proteases (caspases) reduces cold injury-induced brain trauma and DNA fragmentation in mice |
| Q28581092 | Inhibitor of apoptosis protein (IAP) survivin is upregulated by oncogenic c-H-Ras |
| Q47962244 | Inhibitors of interleukin-1 beta-converting enzyme-family proteases (caspases) prevent apoptosis without affecting decreased cellular ability to reduce 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide in cerebellar granule neurons |
| Q37174527 | Inhibitory effect of PACAP on caspase activity in neuronal apoptosis: a better understanding towards therapeutic applications in neurodegenerative diseases. |
| Q42163956 | Insulin-like growth factor-1 protects peroxynitrite-induced cell death by preventing cytochrome c-induced caspase-3 activation |
| Q47068787 | Interaction between the C. elegans cell-death regulators CED-9 and CED-4. |
| Q39831554 | Interaction of Yersinia enterocolitica with macrophages leads to macrophage cell death through apoptosis |
| Q33927889 | Interactions between protein kinases and proteases in cellular signaling and regulation |
| Q30820444 | Interactions of fluorochrome-labeled caspase inhibitors with apoptotic cells: a caution in data interpretation |
| Q42041073 | Interleukin 1 beta-converting enzyme related proteases/caspases are involved in TRAIL-induced apoptosis of myeloma and leukemia cells |
| Q74629939 | Interleukin-1 |
| Q74746989 | Interleukin-1 receptors: cloning studies and role in central nervous system disorders |
| Q47912627 | Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist |
| Q37378111 | Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells |
| Q33541966 | Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1). |
| Q64275741 | Interleukin-18 in Health and Disease |
| Q77355821 | Interleukin-18: a novel cytokine that augments both innate and acquired immunity |
| Q48483688 | Interleukin-1beta and its type 1 receptor are expressed in developing neural circuits in the frog, Xenopus laevis. |
| Q34727085 | Interleukin-1beta converting enzyme (caspase-1) in intestinal inflammation |
| Q41080929 | Internucleosomal DNA cleavage triggered by plasma membrane damage during necrotic cell death. Involvement of serine but not cysteine proteases |
| Q42799434 | Intracellular expression of the Salmonella plasmid virulence protein, SpvB, causes apoptotic cell death in eukaryotic cells |
| Q39494190 | Intranasal Delivery of a Caspase-1 Inhibitor in the Treatment of Global Cerebral Ischemia |
| Q59796999 | Investigation of Different Molecular Weight Fucoidan Fractions Derived from New Zealand in Combination with GroA Therapy in Prostate Cancer Cell Lines |
| Q42815566 | Involvement of PARP and poly(ADP-ribosyl)ation in the early stages of apoptosis and DNA replication |
| Q24338605 | Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death |
| Q40813721 | Involvement of caspases in 4-hydroxy-alkenal-induced apoptosis in human leukemic cells |
| Q28143624 | Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation |
| Q44506014 | Involvement of hydrogen peroxide in mistletoe lectin-II-induced apoptosis of myeloleukemic U937 cells |
| Q43688069 | Involvement of transcriptional repressor ATF3 in acceleration of caspase protease activation during DNA damaging agent-induced apoptosis |
| Q39500745 | Ipr1 gene mediates RAW 264.7 macrophage cell line resistance to Mycobacterium bovis |
| Q38112400 | Iron chelation in the treatment of cancer: a new role for deferasirox? |
| Q52567838 | Is apoptosis involved in mechanisms to eliminate Onchocerca ochengi during Simulium damnosum s.l. immune response? |
| Q52195654 | Is programmed cell death required for neural tube closure? |
| Q38541496 | Isatin sulfonamides: potent caspases-3 and -7 inhibitors, and promising PET and SPECT radiotracers for apoptosis imaging |
| Q39077576 | Ischemia-reperfusion induces renal tubule pyroptosis via the CHOP-caspase-11 pathway |
| Q73983298 | Isolation and assay of caspases |
| Q44137071 | Isolation of AmphiCASP-3/7, an ancestral caspase from amphioxus (Branchiostoma floridae). Evolutionary considerations for vertebrate caspases |
| Q33998751 | Jasplakinolide induces apoptosis in various transformed cell lines by a caspase-3-like protease-dependent pathway |
| Q38557771 | Journey of cystatins from being mere thiol protease inhibitors to at heart of many pathological conditions |
| Q33897202 | Kinase inhibitors in cancer therapy: a look ahead |
| Q28144782 | Knock-out of the neural death effector domain protein PEA-15 demonstrates that its expression protects astrocytes from TNFalpha-induced apoptosis |
| Q74424476 | Lamin B phosphorylation by protein kinase calpha and proteolysis during apoptosis in human leukemia HL60 cells |
| Q48259430 | Leptolyngbyolides, Cytotoxic Macrolides from the Marine Cyanobacterium Leptolyngbya sp.: Isolation, Biological Activity, and Catalytic Asymmetric Total Synthesis. |
| Q27935502 | Life-span extension by a metacaspase in the yeast Saccharomyces cerevisiae |
| Q74332838 | Link of a new type of apoptosis-inducing gene ASY/Nogo-B to human cancer |
| Q35047180 | Lipoapoptosis: its mechanism and its diseases |
| Q39509088 | Lipopolysaccharide stimulates butyric acid-induced apoptosis in human peripheral blood mononuclear cells |
| Q87402389 | Livin, Survivin and Caspase 3 as early recurrence markers in non-muscle-invasive bladder cancer |
| Q37727151 | Local effects of the sphingosine 1-phosphate on prostaglandin F2alpha-induced luteolysis in the pregnant rat |
| Q46623649 | Local pruning of dendrites and spines by caspase-3-dependent and proteasome-limited mechanisms. |
| Q40513940 | Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics |
| Q28607413 | Loss of gene function and evolution of human phenotypes |
| Q40355691 | Loss of mitochondrial membrane potential and caspase activation enhance apoptosis in irradiated K562 cells treated with herbimycin A. |
| Q28343599 | Lupus-prone mice as models to study xenobiotic-induced acceleration of systemic autoimmunity |
| Q28267461 | MALT1 is not alone after all: identification of novel paracaspases |
| Q33996873 | MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis |
| Q24656254 | MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death |
| Q36063767 | Macrophages resistant to endogenously generated nitric oxide-mediated apoptosis are hypersensitive to exogenously added nitric oxide donors: dichotomous apoptotic response independent of caspase 3 and reversal by the mitogen-activated protein kinase |
| Q28587642 | Male sterility in mice lacking retinoic acid receptor alpha involves specific abnormalities in spermiogenesis |
| Q45300831 | Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant. |
| Q36302900 | Mammalian initiator apoptotic caspases |
| Q23912025 | Manganese-induced cytotoxicity in dopamine-producing cells |
| Q35120771 | Mechanism of HIV-1 viral protein R-induced apoptosis |
| Q57460039 | Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor |
| Q34277873 | Mechanisms behind the inhibition of lung adenocarcinoma cell by shikonin |
| Q77485539 | Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis |
| Q56609201 | Mechanisms of apoptosis |
| Q37085889 | Mechanisms of apoptosis resistance and treatment strategies to overcome them in hormone-refractory prostate cancer |
| Q27919623 | Mechanisms of caspase activation and inhibition during apoptosis |
| Q28389576 | Mechanisms of nanosized titanium dioxide-induced testicular oxidative stress and apoptosis in male mice |
| Q36045199 | Mechanisms of neural cell death: implications for development of neuroprotective treatment strategies |
| Q33662619 | Mechanisms of nitric oxide-dependent apoptosis: involvement of mitochondrial mediators |
| Q33186136 | Mechanisms of staurosporine induced apoptosis in a human corneal endothelial cell line |
| Q42491893 | Mechanisms to prevent the toxicity of chronic neuroinflammation on forebrain cholinergic neurons |
| Q50738597 | Melatonin promotes the in vitro development of pronuclear embryos and increases the efficiency of blastocyst implantation in murine. |
| Q34341346 | Membrane damage during Listeria monocytogenes infection triggers a caspase-7 dependent cytoprotective response |
| Q41059135 | Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal |
| Q84561174 | Metacaspases are not caspases--always doubt |
| Q41619830 | Methods for detecting and quantifying apoptosis. |
| Q64074554 | MicroRNA Post-transcriptional Regulation of the NLRP3 Inflammasome in Immunopathologies |
| Q50970217 | Microfluidic Encapsulation of Prickly Zinc-Doped Copper Oxide Nanoparticles with VD1142 Modified Spermine Acetalated Dextran for Efficient Cancer Therapy. |
| Q44017862 | Microtubule damaging agents induce apoptosis in HL 60 cells and G2/M cell cycle arrest in HT 29 cells |
| Q35124329 | Microvesicular caspase-1 mediates lymphocyte apoptosis in sepsis |
| Q33908944 | Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease |
| Q38000429 | Mitochondrial Ca(2+) and apoptosis |
| Q54195696 | Mitochondrial and caspase pathways are involved in the induction of apoptosis by IB-MECA in ovarian cancer cell lines. |
| Q33887952 | Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. |
| Q39446000 | Mitochondrial regulation of cell death: mitochondria are essential for procaspase 3-p21 complex formation to resist Fas-mediated cell death |
| Q59091303 | Modulatory in vitro effects of interleukin-1 receptor antagonist (IL-1Ra) or antisense oligonucleotide to interleukin-1beta converting enzyme (ICE) on acute myeloid leukaemia (AML) cell growth |
| Q36158929 | Molecular aetiology and pathogenesis of basal cell carcinoma |
| Q37658107 | Molecular and biochemical characterization of the NS1 protein of non-cultured influenza B virus strains circulating in Singapore |
| Q33784802 | Molecular and cellular analysis of human immunodeficiency virus-induced apoptosis in lymphoblastoid T-cell-line-expressing wild-type and mutated CD4 receptors |
| Q33534055 | Molecular and genetic basis of normal and toxicant-induced apoptosis in female germ cells |
| Q33857383 | Molecular cloning and characterization of two novel pro-apoptotic isoforms of caspase-10. |
| Q28180414 | Molecular evidence for the nuclear localization of FADD |
| Q41537690 | Molecular mechanisms in cell-mediated cytotoxicity |
| Q37027281 | Molecular mechanisms of apoptosis in cerebral ischemia: multiple neuroprotective opportunities |
| Q40452005 | Molecular mechanisms of apoptosis induced by Scorpio water extract in human hepatoma HepG2 cells. |
| Q34072607 | Molecular mechanisms of apoptosis induced by cytotoxic chemicals |
| Q29617861 | Molecular mechanisms of caspase regulation during apoptosis |
| Q33936867 | Molecular mechanisms of cell death in the ear. |
| Q34604104 | Molecular mechanisms of leptin and pro-apoptotic signals induced by menadione in HepG2 cells |
| Q60735522 | Molecular morphology of neuronal apoptosis: Analysis of caspase 3 activation during postnatal development of mouse cerebellar cortex |
| Q35096123 | Molecular pathways in cerebral ischemia: cues to novel therapeutic strategies. |
| Q33506630 | Monocyte derived microvesicles deliver a cell death message via encapsulated caspase-1. |
| Q33212295 | Monocytes are highly sensitive to clostridium difficile toxin A-induced apoptotic and nonapoptotic cell death |
| Q45153051 | Morphological irregularities and features of resistance to apoptosis in the dcp-1/pita double mutated egg chambers during Drosophila oogenesis. |
| Q74014346 | Mouse mammary gland involution is associated with cytochrome c release and caspase activation |
| Q33886502 | Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells |
| Q50444901 | Mushroom lectin protects arsenic induced apoptosis in hepatocytes of rodents. |
| Q34608399 | Mutational analysis of the Caenorhabditis elegans cell-death gene ced-3. |
| Q24527273 | Myxoma virus Serp2 is a weak inhibitor of granzyme B and interleukin-1beta-converting enzyme in vitro and unlike CrmA cannot block apoptosis in cowpox virus-infected cells |
| Q27757254 | NMR structure and mutagenesis of the FADD (Mort1) death-effector domain |
| Q58855408 | NO-aspirin protects from T cell–mediated liver injury by inhibiting caspase-dependent processing of Th1-like cytokines |
| Q43716993 | NO-mesalamine protects colonic epithelial cells against apoptotic damage induced by proinflammatory cytokines |
| Q41049514 | Necessity of interleukin-1beta converting enzyme cascade in taxotere-initiated death signaling |
| Q44659617 | Need for caspases in apoptosis of trophic factor-deprived PC12 cells |
| Q34487157 | Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90 |
| Q38423405 | Negative regulation of the inflammasome: keeping inflammation under control. |
| Q37060101 | Neurodegeneration and inflammation |
| Q36565588 | Neuronal apoptosis in neurodegenerative diseases: from basic research to clinical application |
| Q52188024 | Neuronal cell death. |
| Q48158410 | Neuronal intracellular pH directly mediates nitric oxide-induced programmed cell death |
| Q34119497 | Neuroprotection by caspase inhibitors |
| Q28390865 | Neuroprotective Effects of Salidroside in the MPTP Mouse Model of Parkinson's Disease: Involvement of the PI3K/Akt/GSK3β Pathway |
| Q52152073 | Neuroprotective effects of a novel translocator protein (18 kDa) ligand, ZBD-2, against focal cerebral ischemia and NMDA-induced neurotoxicity. |
| Q46170696 | Neuroprotective effects of formononetin against NMDA-induced apoptosis in cortical neurons |
| Q42851045 | New isolation technique to study apoptosis in human intestinal epithelial cells |
| Q33610146 | Nitric oxide and apoptosis |
| Q78094837 | Nitric oxide protects PC12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling |
| Q74449673 | Nitrosative and oxidative stress induced heme oxygenase-1 accumulation in rat mesangial cells |
| Q33798048 | No longer an exclusive club: eukaryotic signalling domains in bacteria |
| Q64130923 | Non-Structural Protein 2B of Human Rhinovirus 16 Activates Both PERK and ATF6 Rather Than IRE1 to Trigger ER Stress |
| Q47793589 | Nonapoptotic functions of Fas/CD95 in the immune response |
| Q34037785 | Noncaspase proteases in apoptosis |
| Q37685335 | Novaferon, a novel recombinant protein produced by DNA-shuffling of IFN-α, shows antitumor effect in vitro and in vivo |
| Q50518226 | Novel mutant green fluorescent protein protease substrates reveal the activation of specific caspases during apoptosis. |
| Q64263219 | Novel sulphonamide benzoquinazolinones as dual EGFR/HER2 inhibitors, apoptosis inducers and radiosensitizers |
| Q24644671 | Nuclear and cell membrane effects contribute independently to the induction of apoptosis in human cells exposed to UVB radiation |
| Q40486900 | Nuclear translocation of caspase-3 is dependent on its proteolytic activation and recognition of a substrate-like protein(s). |
| Q59783959 | Oligodendrocyte apoptosis mediated by caspase activation |
| Q36795978 | Oncogene-dependent apoptosis is mediated by caspase-9. |
| Q34074249 | One path to cell death in the nervous system |
| Q44644651 | Optical imaging detects apoptosis in the brain and peripheral organs of prion-infected mice |
| Q55475037 | Ordering of ceramide formation, caspase activation, and Bax/Bcl-2 expression during etoposide-induced apoptosis in C6 glioma cells. |
| Q22008727 | Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner |
| Q40040281 | Oridonin induces human epidermoid carcinoma A431 cell apoptosis through tyrosine kinase and mitochondrial pathway |
| Q32052625 | Ovarian toxicity of 4-vinylcyclohexene diepoxide: a mechanistic model |
| Q40291958 | Overexpression of Aurora-A kinase promotes tumor cell proliferation and inhibits apoptosis in esophageal squamous cell carcinoma cell line |
| Q36619620 | Overexpression of IL-1ra gene up-regulates interleukin-1beta converting enzyme (ICE) gene expression: possible mechanism underlying IL-1beta-resistance of cancer cells |
| Q40887003 | Overexpression of catalase in the mitochondrial or cytosolic compartment increases sensitivity of HepG2 cells to tumor necrosis factor-alpha-induced apoptosis |
| Q36193355 | Overexpression of programmed cell death 5 in a mouse model of ovalbumin-induced allergic asthma |
| Q30368988 | Overview of protein structural and functional folds. |
| Q41673383 | Oxidative Stress in Oral Diseases: Understanding Its Relation with Other Systemic Diseases |
| Q43680829 | Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cells |
| Q39880426 | Oxidative modification of caspase-9 facilitates its activation via disulfide-mediated interaction with Apaf-1. |
| Q74341665 | Oxidative stress and apoptosis |
| Q34733245 | Oxidative stress in phagocytes--"the enemy within". |
| Q73616950 | Oxidative stress induces caspase-independent retinal apoptosis in vitro |
| Q77962326 | P53 mediates ceramide-induced apoptosis in SKN-SH cells |
| Q35700283 | PEA-15 modulates TNFalpha intracellular signaling in astrocytes |
| Q37075705 | PQ1, a quinoline derivative, induces apoptosis in T47D breast cancer cells through activation of caspase-8 and caspase-9 |
| Q28374373 | Paclitaxel-induced apoptosis in non-small cell lung cancer cell lines is associated with increased caspase-3 activity |
| Q28187644 | Pathophysiological roles for IL-18 in inflammatory arthritis |
| Q37038484 | Pathophysiology of cutaneous lupus erythematosus |
| Q34476981 | Pathways of apoptosis and the modulation of cell death in cancer |
| Q35852309 | Pathways of apoptotic and non-apoptotic death in tumour cells |
| Q47734726 | Peptide inhibitors of caspase-3-like proteases attenuate 1-methyl-4-phenylpyridinum-induced toxicity of cultured fetal rat mesencephalic dopamine neurons |
| Q33937941 | Peptide targeting of platinum anti-cancer drugs |
| Q77743844 | Peptidomimetic aminomethylene ketone inhibitors of interleukin-1 beta-converting enzyme (ICE) |
| Q54091040 | Peptidyl beta-homo-aspartals (3-amino-4-carboxybutyraldehydes): new specific inhibitors of caspases. |
| Q77748847 | Peptidyl beta-homo-aspartals: specific inhibitors of interleukin-1 beta converting enzyme and its homologues (caspases) |
| Q37370249 | Perspectives series: host/pathogen interactions. Apoptosis in bacterial pathogenesis |
| Q33682659 | Pharmacodynamics and toxicodynamics of drug action: signaling in cell survival and cell death |
| Q40251505 | Phellinus linteus sensitises apoptosis induced by doxorubicin in prostate cancer |
| Q40971137 | Phosphatidylinositol 3-kinase and protein kinase C are required for the inhibition of caspase activity by epidermal growth factor |
| Q38560204 | Phytoconstituents as apoptosis inducing agents: strategy to combat cancer |
| Q37244373 | Plant programmed cell death: can't live with it; can't live without it. |
| Q33764232 | Poly(ADP-ribosylation) and apoptosis. |
| Q47849301 | Posttranslational protein modifications, apoptosis, and the bypass of tolerance to autoantigens |
| Q42538252 | Potentiation of paclitaxel cytotoxicity by inostamycin in human small cell lung carcinoma, Ms-1 cells |
| Q22009395 | Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells |
| Q33181375 | Prevention of mucosal atrophy: role of glutamine and caspases in apoptosis in intestinal epithelial cells |
| Q53564659 | Pro-apoptotic activity of imidazole derivatives mediated by up-regulation of Bax and activation of CAD in Ehrlich Ascites Tumor cells. |
| Q74082796 | Procaspase 3/p21 complex formation to resist fas-mediated cell death is initiated as a result of the phosphorylation of p21 by protein kinase A |
| Q44611177 | Progesterone-induced apoptosis in immortalized normal and malignant human ovarian surface epithelial cells involves enhanced expression of FasL |
| Q41851342 | Programmed Cell Death During Caenorhabditis elegans Development |
| Q29616430 | Programmed cell death in animal development |
| Q34152257 | Programmed cell death in plant reproduction |
| Q46368663 | Programmed cell death in the retina. Molecular mechanisms and therapeutic strategies |
| Q34634857 | Programmed cell death takes flight: genetic and genomic approaches to gene discovery in Drosophila. |
| Q48373661 | Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation |
| Q41517771 | Prospects for altering host range for baculovirus bioinsecticides |
| Q43832571 | Prostaglandin E(2) induces caspase-dependent apoptosis in rat cortical cells |
| Q36452771 | Protease probes built from DNA: multispectral fluorescent DNA-peptide conjugates as caspase chemosensors |
| Q33927179 | Proteases for cell suicide: functions and regulation of caspases |
| Q34476390 | Proteases in cardiometabolic diseases: Pathophysiology, molecular mechanisms and clinical applications |
| Q36292074 | Protective Role of Oleuropein against Acute Deltamethrin-Induced Neurotoxicity in Rat Brain |
| Q53749321 | Protective effect of apigenin on ischemia/reperfusion injury of the isolated rat heart. |
| Q40370002 | Protective effect of zinc on amyloid-beta 25-35 and 1-40 mediated toxicity. |
| Q49178482 | Protective effects of atorvastatin on cerebral vessel autoregulation in an experimental rabbit model of subarachnoid hemorrhage. |
| Q24682097 | Proteolytic activation of PKN by caspase-3 or related protease during apoptosis |
| Q41038385 | Proteolytic cleavage of HsRad51 during apoptosis |
| Q32065143 | Proteolytic cleavage of epidermal growth factor receptor by caspases. |
| Q38343171 | Proteolytic cleavage of the mdm2 oncoprotein during apoptosis |
| Q39320300 | Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations |
| Q35161589 | Proteolytic signaling by TNFalpha: caspase activation and IkappaB degradation |
| Q74661957 | Proteolytic specificity of caspases is required to signal the appearance of apoptotic morphology |
| Q33889305 | Protooncogenes as mediators of apoptosis |
| Q41080130 | Purines and their roles in apoptosis |
| Q28480617 | Quercetin-4'-O-β-D-glucopyranoside (QODG) inhibits angiogenesis by suppressing VEGFR2-mediated signaling in zebrafish and endothelial cells |
| Q78707955 | Radiation-induced crypt intestinal epithelial cell apoptosis in vivo involves both caspase-3-dependent and -independent pathways |
| Q50517391 | Rainbow trout (Oncorhynchus mykiss) shift the age composition of circulating red blood cells towards a younger cohort when exposed to thermal stress. |
| Q30310781 | Rapid Apoptosis Induced by Shiga Toxin in HeLa Cells |
| Q52713473 | Rapid cold-hardening blocks cold-induced apoptosis by inhibiting the activation of pro-caspases in the flesh fly Sarcophaga crassipalpis. |
| Q28371236 | Rapid nucleolytic degradation of the small cytoplasmic Y RNAs during apoptosis |
| Q36301422 | Rat optic nerve oligodendrocytes develop in the absence of viable retinal ganglion cell axons |
| Q33609434 | Reactive oxygen intermediates regulate cellular response to apoptotic stimuli: an hypothesis |
| Q36491838 | Recent advances in targeting regulators of apoptosis in cancer cells for therapeutic gain |
| Q34274842 | Receptor-mediated choreography of life and death. |
| Q41737516 | Receptors and ligands that mediate activation-induced death of T cells |
| Q39511886 | Recombinant immunotoxin anti-c-Met/PE38KDEL inhibits proliferation and promotes apoptosis of gastric cancer cells |
| Q45749326 | Recruitment of apoptotic cysteine proteases (caspases) in influenza virus-induced cell death |
| Q37784826 | Redox Regulation of the Intrinsic Pathway in Neuronal Apoptosis |
| Q29618617 | Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9 |
| Q73333075 | Reduction of post-traumatic brain injury and free radical production by inhibition of the caspase-1 cascade |
| Q58584832 | Regulating Apoptosis by Degradation: The N-End Rule-Mediated Regulation of Apoptotic Proteolytic Fragments in Mammalian Cells |
| Q37256980 | Regulation of B-cell entry into the cell cycle |
| Q44028246 | Regulation of Bcl-2 family molecules and activation of caspase cascade involved in gypenosides-induced apoptosis in human hepatoma cells |
| Q28215242 | Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins |
| Q36254811 | Regulation of caspase activation in apoptosis: implications for transformation and drug resistance |
| Q35792765 | Regulation of caspase-9 activity by differential binding to the apoptosome complex |
| Q27003645 | Regulation of cell death by transfer RNA |
| Q29615554 | Regulation of cell death: the calcium-apoptosis link |
| Q34117899 | Regulation of death receptor-mediated apoptosis pathways |
| Q77162251 | Regulation of the new coexpressed CD55 (decay-accelerating factor) receptor on stomach carcinoma cells involved in antibody SC-1-induced apoptosis |
| Q74449240 | Release of mitochondrial cytochrome c is upstream of caspase activation in chemical-induced apoptosis in human monocytic tumour cells |
| Q38157474 | Relevance of signaling molecules for apoptosis induction on influenza A virus replication |
| Q38062583 | Renal cell apoptosis and new treatment options in sepsis-induced acute kidney injury |
| Q34536479 | Reprieval from execution: the molecular basis of caspase inhibition |
| Q47072155 | Requirement for DCP-1 caspase during Drosophila oogenesis |
| Q40243606 | Requirement for pre-existing of p21 to prevent doxorubicin-induced apoptosis through inhibition of caspase-3 activation |
| Q77359861 | Requirement of caspase-3(-like) protease-mediated hydrogen peroxide production for apoptosis induced by various anticancer drugs |
| Q51101238 | Requirement of the caspase-3/CPP32 protease cascade for apoptotic death following cytokine deprivation in hematopoietic cells. |
| Q57384656 | Resistance of cultured peripheral T cells towards activation-induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death-inducing signaling complex |
| Q41019934 | Resistance to etoposide-induced apoptosis in a Burkitt's lymphoma cell line |
| Q42710453 | Resveratrol inhibits fibrogenesis and induces apoptosis in keloid fibroblasts |
| Q44553365 | Resveratrol modulates apoptosis and oxidation in human blood mononuclear cells |
| Q34293450 | Resveratrol--from the bottle to the bedside? |
| Q28379199 | Retinoid-induced apoptosis and Sp1 cleavage occur independently of transcription and require caspase activation |
| Q34662282 | Revisiting caspases in sepsis |
| Q33181921 | Ribozyme-mediated inhibition of caspase-3 activity reduces apoptosis induced by 6-hydroxydopamine in PC12 cells |
| Q51645773 | Ribozyme-mediated inhibition of caspase-3 protects cerebellar granule cells from apoptosis induced by serum-potassium deprivation. |
| Q34483368 | Role of Bid-induced mitochondrial outer membrane permeabilization in granzyme B-induced apoptosis |
| Q35910747 | Role of DNA mismatch repair in apoptotic responses to therapeutic agents |
| Q33853255 | Role of apoptosis in gastric epithelial turnover |
| Q50527419 | Role of caspases (ICE/CED 3 proteases) in DNA damage and cell death in response to a mitochondrial inhibitor, antimycin A. |
| Q35299643 | Role of caspases in renal tubular epithelial cell injury |
| Q40792857 | Role of ceramide during cisplatin-induced apoptosis in C6 glioma cells |
| Q35877449 | Role of early and late replication events in induction of apoptosis by baculoviruses |
| Q54083194 | Role of poly(ADP-ribose) polymerase (PARP) cleavage in apoptosis. Caspase 3-resistant PARP mutant increases rates of apoptosis in transfected cells. |
| Q33608788 | Role of the Bcl-2 gene family in prostate cancer progression and its implications for therapeutic intervention |
| Q36571858 | Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis |
| Q38856168 | Role of tumor necrosis factor-alpha and the modulating effect of the caspases in rat corpus luteum apoptosis |
| Q33927861 | Roles of poly(ADP-ribosyl)ation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1. |
| Q40943583 | Room temperature-induced apoptosis of Jurkat cells sensitive to both caspase-1 and caspase-3 inhibitors |
| Q40602856 | S-Nitrosation regulates the activation of endogenous procaspase-9 in HT-29 human colon carcinoma cells |
| Q38305316 | SADS: A new component of Fas-DISC is the accelerator for cell death signaling and is downregulated in patients with colon carcinoma |
| Q22010638 | SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein |
| Q50116741 | Salmonella typhimurium induces apoptosis in human monocyte-derived macrophages. |
| Q32177594 | Salvia miltiorrhiza extract dihydrotanshinone induces apoptosis and inhibits proliferation of glioma cells |
| Q28536983 | Searching in mother nature for anti-cancer activity: anti-proliferative and pro-apoptotic effect elicited by green barley on leukemia/lymphoma cells |
| Q42550974 | Selective activation of caspases during apoptotic induction in HL-60 cells. Effects Of a tetrapeptide inhibitor |
| Q77669509 | Selective involvement of caspase-3 in ceramide induced apoptosis in AK-5 tumor cells |
| Q73561060 | Selenite negatively regulates caspase-3 through a redox mechanism |
| Q40951467 | Sequential cleavage of poly(ADP-ribose)polymerase and appearance of a small Bax-immunoreactive protein are blocked by Bcl-X(L) and caspase inhibitors during staurosporine-induced dopaminergic neuronal apoptosis |
| Q43649378 | Sequential two-step cleavage of the retinoblastoma protein by caspase-3/-7 during etoposide-induced apoptosis |
| Q28289989 | Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB |
| Q33683189 | Signal transduction pathways that regulate the fate of B lymphocytes. |
| Q58883548 | Signalling by proteolysis: death receptors induce apoptosis |
| Q33754728 | Silencing of PTK7 in colon cancer cells: caspase-10-dependent apoptosis via mitochondrial pathway |
| Q40818471 | Silencing of the caspase-1 gene occurs in murine and human renal cancer cells and causes solid tumor growth in vivo |
| Q58115643 | Simultaneous Degradation of αII- and βII-Spectrin by Caspase 3 (CPP32) in Apoptotic Cells |
| Q24646161 | Small-molecule Bcl-2 antagonists as targeted therapy in oncology |
| Q34510593 | Sodium selenite improves folliculogenesis in radiation-induced ovarian failure: a mechanistic approach |
| Q34413612 | Spodoptera frugiperda caspase-1, a novel insect death protease that cleaves the nuclear immunophilin FKBP46, is the target of the baculovirus antiapoptotic protein p35. |
| Q36622774 | Squamous cell carcinoma antigen suppresses radiation-induced cell death |
| Q39220490 | Statins and voriconazole induce programmed cell death in Acanthamoeba castellanii |
| Q43652217 | Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms |
| Q49106082 | Staurosporine- and H-7-induced cell death in SH-SY5Y neuroblastoma cells is associated with caspase-2 and caspase-3 activation, but not with activation of the FAS/FAS-L-caspase-8 signaling pathway. |
| Q39476761 | Staurosporine-induced apoptosis of cultured rat hippocampal neurons involves caspase-1-like proteases as upstream initiators and increased production of superoxide as a main downstream effector. |
| Q37162061 | Strategies to promote donor cell survival: combining preconditioning approach with stem cell transplantation |
| Q38643071 | Strategies to release doxorubicin from doxorubicin delivery vehicles |
| Q36243108 | Structural and functional aspects of the liver and liver sinusoidal cells in relation to colon carcinoma metastasis |
| Q22010148 | Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1 |
| Q55066927 | Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases. |
| Q73094132 | Superoxide anion inhibits drug-induced tumor cell death |
| Q36397702 | Suppression of P-gp induced multiple drug resistance in a drug resistant gastric cancer cell line by overexpression of Fas |
| Q43745253 | Suppression of T(3)- and fatty acid-induced membrane permeability transition by L-carnitine |
| Q40911601 | Survival and proliferation of cells expressing caspase-uncleavable Poly(ADP-ribose) polymerase in response to death-inducing DNA damage by an alkylating agent |
| Q52166351 | Survivin initiates cell cycle entry by the competitive interaction with Cdk4/p16(INK4a) and Cdk2/cyclin E complex activation. |
| Q28138374 | Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death |
| Q44035186 | Synapse-independent and synapse-dependent apoptosis of cerebellar granule cells in postnatal rabbits occur at two subsequent but partly overlapping developmental stages |
| Q35027638 | Synergistic effects of caspase inhibitors and MK-801 in brain injury after transient focal cerebral ischaemia in mice |
| Q57007289 | Synthetic peptide conjugates—tailor-made probes for the biology of protein modification and protein processing |
| Q33886507 | T-cell receptor ligation by peptide/MHC induces activation of a caspase in immature thymocytes: the molecular basis of negative selection. |
| Q73207865 | THP-1 monocytic leukemia cells express Fas ligand constitutively and kill Fas-positive Jurkat cells |
| Q74083351 | TRAIL-induced apoptosis of thyroid cancer cells: potential for therapeutic intervention |
| Q34482821 | TRAIL/Apo-2L: mechanisms and clinical applications in cancer |
| Q31625558 | Tamoxifen but not 4-hydroxytamoxifen initiates apoptosis in p53(-) normal human mammary epithelial cells by inducing mitochondrial depolarization |
| Q73103920 | Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases |
| Q33898831 | Target sites for manipulating apoptosis in prostate cancer |
| Q52928024 | Targeted delivery of a novel anticancer compound anisomelic acid using chitosan-coated porous silica nanorods for enhancing the apoptotic effect. |
| Q36999705 | Targeted therapies in non-small cell lung carcinoma: what have we achieved so far? |
| Q37650181 | Targeting AAC-11 in cancer therapy |
| Q89840958 | Targeting apoptotic caspases in cancer |
| Q36349902 | Targeting caspase-6 and caspase-8 to promote neuronal survival following ischemic stroke. |
| Q26821986 | Targeting caspases in cancer therapeutics |
| Q35095412 | Targeting ischemic cardiac dysfunction through gene transfer |
| Q35577256 | The "fuzzy logic" of the death-inducing signaling complex in lymphocytes |
| Q24316760 | The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis |
| Q42540863 | The Ah receptor is not involved in 2,3,7,8-tetrachlorodibenzo- p-dioxin-mediated apoptosis in human leukemic T cell lines |
| Q57064676 | The Benefit of Anti-Inflammatory and Renal-Protective Dietary Ingredients on the Biological Processes of Aging in the Kidney |
| Q22248066 | The C Terminus of HIV-1 Tat Modulates the Extent of CD178-mediated Apoptosis of T Cells |
| Q40837805 | The C. elegans orthologue ceBNIP3 interacts with CED-9 and CED-3 but kills through a BH3- and caspase-independent mechanism |
| Q47927402 | The CD8+ granzyme B+ T-cell subset in peripheral blood from healthy individuals contains activated and apoptosis-prone cells. |
| Q56888336 | The CaspBase: A curated database for evolutionary biochemical studies of caspase functional divergence and ancestral sequence inference |
| Q48375362 | The Dorothy Russell Memorial Lecture. The molecular and cellular sequelae of experimental traumatic brain injury: pathogenetic mechanisms |
| Q41689719 | The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID. |
| Q40977272 | The Fanconi anemia group C gene product modulates apoptotic responses to tumor necrosis factor-alpha and Fas ligand but does not suppress expression of receptors of the tumor necrosis factor receptor superfamily |
| Q40308561 | The NS5A protein of the hepatitis C virus genotype 1a is cleaved by caspases to produce C-terminal-truncated forms of the protein that reside mainly in the cytosol |
| Q38909275 | The Orchestra and Its Maestro: Shigella's Fine-Tuning of the Inflammasome Platforms. |
| Q28512341 | The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1 |
| Q53605122 | The WT1 Wilms' tumor suppressor gene is a downstream target for insulin-like growth factor-I (IGF-I) action in PC12 cells. |
| Q46897870 | The affinity of a major Ca2+ binding site on GRP78 is differentially enhanced by ADP and ATP. |
| Q28246509 | The alpha4 laminin subunit regulates endothelial cell survival |
| Q45226287 | The alteration of protein profile of Walker 256 carinosarcoma cells during the apoptotic process induced by ultrasound |
| Q46254868 | The ameliorative effects of L-2-oxothiazolidine-4-carboxylate on acetaminophen-induced hepatotoxicity in mice |
| Q24318700 | The antiapoptotic protein AAC-11 interacts with and regulates Acinus-mediated DNA fragmentation |
| Q35133344 | The apoptosis database |
| Q36766418 | The apoptosome: signalling platform of cell death |
| Q29547741 | The biochemistry of apoptosis |
| Q36255096 | The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling |
| Q34980881 | The chemical biology of apoptosis. Exploring protein-protein interactions and the life and death of cells with small molecules |
| Q40700265 | The clinical significance of caspase regulation in acute leukemia |
| Q34024722 | The conservation and uniqueness of the caspase family in the basal chordate, amphioxus |
| Q35248175 | The construction of common and specific significance subnetworks of Alzheimer's disease from multiple brain regions |
| Q47833047 | The effects of grape seed on apoptosis-related gene expression and oxidative stress in streptozotocin-induced diabetic rats |
| Q35213602 | The facts of death |
| Q46300705 | The first report of diablo in Megalobrama amblycephala: characterization, phylogenetic analysis, functional annotation and expression. |
| Q50469530 | The fruits of wampee inhibit H2O2-induced apoptosis in PC12 cells via the NF-κB pathway and regulation of cellular redox status. |
| Q51940684 | The gene expression profile in refractory periodontitis patients. |
| Q44313525 | The human caspase-2 gene: alternative promoters, pre-mRNA splicing and AUG usage direct isoform-specific expression. |
| Q36761589 | The hypothalamic-pituitary-thyroid (HPT) axis in frogs and its role in frog development and reproduction |
| Q24305136 | The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta |
| Q35560355 | The interleukin 1beta-converting enzyme, caspase 1, is activated during Shigella flexneri-induced apoptosis in human monocyte-derived macrophages |
| Q28206616 | The kiss of death: promises and failures of death receptors and ligands in cancer therapy |
| Q28244608 | The large subunit of the DNA replication complex C (DSEB/RF-C140) cleaved and inactivated by caspase-3 (CPP32/YAMA) during Fas-induced apoptosis |
| Q34466450 | The machinery of programmed cell death. |
| Q30882099 | The multifunctional protein PEA-15 is involved in the control of apoptosis and cell cycle in astrocytes |
| Q37388996 | The novel caspase-3 substrate Gap43 is involved in AMPA receptor endocytosis and long-term depression |
| Q33656349 | The nuclear γ-H2AX apoptotic ring: implications for cancers and autoimmune diseases |
| Q40583071 | The pro-apoptotic protein Bim is a convergence point for cAMP/protein kinase A- and glucocorticoid-promoted apoptosis of lymphoid cells |
| Q40732487 | The protection of hybridoma cells from apoptosis by caspase inhibition allows culture recovery when exposed to non-inducing conditions. |
| Q35902423 | The protein structures that shape caspase activity, specificity, activation and inhibition |
| Q28610855 | The proteolytic cleavage of protein kinase C isotypes, which generates kinase and regulatory fragments, correlates with Fas-mediated and 12-O-tetradecanoyl-phorbol-13-acetate-induced apoptosis |
| Q48637409 | The role of CED-3-related cysteine proteases in apoptosis of cerebellar granule cells. |
| Q45296306 | The role of apoptosis in neurodegenerative diseases |
| Q39727971 | The role of c-FLIP(L) in ovarian cancer: chaperoning tumor cells from immunosurveillance and increasing their invasive potential. |
| Q43671168 | The role of calpain in caspase activation during etoposide induced apoptosis in T cells |
| Q33686145 | The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice. |
| Q31327765 | The role of natural killer cell mediated caspases activation in a graft-versus-host disease model of semiallogeneic small bowel transplantation |
| Q41659044 | The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy |
| Q24814926 | The roles of Bcl-xL in modulating apoptosis during development of Xenopus laevis |
| Q22254013 | The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells |
| Q40872725 | The short prodomain influences caspase-3 activation in HeLa cells |
| Q34602545 | The significance of immunohistochemistry in the diagnosis and therapy of neoplasms |
| Q34672064 | The small GTPase Cdc42 initiates an apoptotic signaling pathway in Jurkat T lymphocytes |
| Q73816253 | The staurosporine analog, Ro-31-8220, induces apoptosis independently of its ability to inhibit protein kinase C |
| Q28116163 | The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases |
| Q94411369 | Therapeutic Potential of Arsenic Trioxide (ATO) in Treatment of Hepatocellular Carcinoma: Role of Oxidative Stress in ATO-Induced Apoptosis |
| Q34411338 | Therapeutic approaches to preventing cell death in Huntington disease |
| Q40368455 | Therapeutic implications of interferon regulatory factor (IRF)-1 and IRF-2 in diffusely infiltrating astrocytomas (DIA): response to interferon (IFN)-beta in glioblastoma cells and prognostic value for DIA. |
| Q34023541 | Thrombin: a neuronal cell modulator |
| Q36206509 | Thyroid hormone receptor β suppresses SV40-mediated tumorigenesis via novel nongenomic actions |
| Q34490899 | Thyroid hormone regulation of apoptotic tissue remodeling during anuran metamorphosis. |
| Q41635889 | Time-dependent proteomic and genomic alterations in Toll-like receptor-4-activated human chondrocytes: increased expression of lamin A/C and annexins |
| Q39095495 | Topotecan-loaded mesoporous silica nanoparticles for reversing multi-drug resistance by synergetic chemoradiotherapy |
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| Q48164528 | Toxic potential of copper-doped ZnO nanoparticles in Drosophila melanogaster (Oregon R). |
| Q34344626 | Transcriptional regulation of the BCL-X gene by NF-kappaB is an element of hypoxic responses in the rat brain |
| Q48513210 | Transient global forebrain ischemia induces a prolonged expression of the caspase-3 mRNA in rat hippocampal CA1 pyramidal neurons. |
| Q41037600 | Transient poly(ADP-ribosyl)ation of nuclear proteins and role of poly(ADP-ribose) polymerase in the early stages of apoptosis |
| Q34062730 | Triggering and modulation of apoptosis by oxidative stress |
| Q39992582 | Troglitazone, a peroxisome proliferator-activated receptor gamma ligand, induces growth inhibition and apoptosis of HepG2 human liver cancer cells |
| Q40507838 | Two different mechanisms of apoptosis resistance observed in interferon-beta induced apoptosis of human glioma cells |
| Q38614761 | Two distinct signaling pathways downstream of Janus kinase 2 play redundant roles for antiapoptotic activity of granulocyte-macrophage colony-stimulating factor |
| Q46928478 | Two non-exclusive strategies employed to protect Torulopsis glabrata against hyperosmotic stress |
| Q39969912 | UVB-induced murine bone marrow derived macrophages and apoptosis |
| Q32152397 | Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L |
| Q58300049 | Ultraviolet radiation‐induced apoptosis is inversely correlated with the expression level of poly(ADP‐ribose) polymerase |
| Q42380693 | Upregulation of P53 promoted G1 arrest and apoptosis in human umbilical cord vein endothelial cells from preeclampsia. |
| Q30991571 | Use of flow and laser-scanning cytometry in analysis of cell death |
| Q34748719 | Use of fluorescently labeled caspase inhibitors as affinity labels to detect activated caspases |
| Q34173884 | Using death to one's advantage: HIV modulation of apoptosis |
| Q34485541 | Using flow cytometry to follow the apoptotic cascade |
| Q52539830 | Vascular apoptosis and involution in gliomas precede neovascularization: a novel concept for glioma growth and angiogenesis. |
| Q40844915 | Vinorelbine induces apoptosis and caspase-3 (CPP32) expression in leukemia and lymphoma cells: a comparison with vincristine |
| Q36925632 | Viral subversion of apoptotic enzymes: escape from death row. |
| Q40415802 | Whole venom of Loxosceles similis activates caspases-3, -6, -7, and -9 in human primary skin fibroblasts |
| Q24314699 | ZIP kinase, a novel serine/threonine kinase which mediates apoptosis |
| Q48284457 | Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures |
| Q78019259 | [Apoptosis--what is it? Significance in coronary heart disease and myocardial infarct] |
| Q28584241 | cDNA cloning and promoter analysis of rat caspase-9 |
| Q36574102 | ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein |
| Q55051577 | microRNA-124-3p inhibits the progression of congenital hypothyroidism via targeting programmed cell death protein 6. |
| Q24318875 | p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum |
| Q42536360 | p53- and p21-independent apoptosis of squamous cell carcinoma cells induced by 5-fluorouracil and radiation |
| Q34305233 | p53-dependent apoptosis pathways. |
| Q24564604 | p53-dependent ceramide response to genotoxic stress |
| Q33670585 | p75 neurotrophin receptor as a modulator of survival and death decisions |
| Q53585472 | sCD30, interleukin-1beta-converting enzyme and anti-Annexin V autoantibodies concentrations in heart transplant recipients. |
| Q61663176 | α-Tocopheryl succinate-induced apoptosis in Jurkat T cells involves caspase-3 activation, and both lysosomal and mitochondrial destabilisation |
| Q36608155 | γδ T Cells and dendritic cells in refractory Lyme arthritis. |
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