scholarly article | Q13442814 |
P50 | author | Richard Flavell | Q2149481 |
Pasko Rakic | Q532002 | ||
P2093 | author name string | Gu Y | |
Karasuyama H | |||
Su MS | |||
Kuida K | |||
Taya C | |||
Kuan CY | |||
Haydar TF | |||
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P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | apoptotic process | Q14599311 |
P304 | page(s) | 325-37 | |
P577 | publication date | 1998-08-07 | |
P1433 | published in | Cell | Q655814 |
P1476 | title | Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9 | |
P478 | volume | 94 |
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Q33923835 | Apoptosis and cell division |
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Q34154044 | Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome |
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Q50889542 | Apoptosis occurs throughout the diseased rotator cuff. |
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Q64982436 | Apoptosis versus axon pruning: Molecular intersection of two distinct pathways for axon degeneration. |
Q36325171 | Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death |
Q34293102 | Apoptosis-regulating proteins as targets for drug discovery |
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Q33777704 | Apoptosis: definition, mechanisms, and relevance to disease |
Q37902996 | Apoptosis: why and how does it occur in biology? |
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Q34753431 | Apoptotic pathways: the roads to ruin |
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Q37921609 | Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases |
Q36696157 | Decision by division: making cortical maps |
Q53922251 | Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2. |
Q78954628 | Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL-/- mice |
Q70607132 | Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation |
Q28590902 | Deficiency of a STE20/PAK family kinase LOK leads to the acceleration of LFA-1 clustering and cell adhesion of activated lymphocytes |
Q41687820 | Defining characteristics of Types I and II apoptotic cells in response to TRAIL. |
Q73315751 | Delaying caspase activation by Bcl-2: A clue to disease retardation in a transgenic mouse model of amyotrophic lateral sclerosis |
Q33880493 | Deletion of Puma protects hippocampal neurons in a model of severe status epilepticus. |
Q52041380 | Deregulated expression of DeltaNp73alpha causes early embryonic lethality. |
Q74228902 | Detection of caspase-9 activation in the cell death of the Bcl-x-deficient mouse embryo nervous system by cleavage sites-directed antisera |
Q34447887 | Detection of mitochondria-mediated apoptosis signaling molecules in ameloblastomas |
Q53499832 | Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy. |
Q34104238 | Developmental mechanisms in the pathogenesis of neurodegenerative diseases |
Q46356966 | Developmental origins of species differences in telencephalon and tectum size: morphometric comparisons between a parakeet (Melopsittacus undulatus) and a quail (Colinus virgianus). |
Q55476097 | Dexamethasone pre-treatment interferes with apoptotic death in glioma cells. |
Q39940601 | Diarylurea compounds inhibit caspase activation by preventing the formation of the active 700-kilodalton apoptosome complex |
Q57274133 | Different Role of Apaf-1 in Positive Selection, Negative Selection and Death by Neglect in Foetal Thymic Organ Culture |
Q43657459 | Differential involvement of initiator caspases in apoptotic volume decrease and potassium efflux during Fas- and UV-induced cell death. |
Q43764281 | Differential regulation of phosphatidylserine externalization and DNA fragmentation by caspases in anticancer drug-induced apoptosis of rat mammary adenocarcinoma MTLn3 cells |
Q48458778 | Differential requirement for Apaf1 and Bcl-X(L) in the regulation of programmed cell death during development. |
Q73540307 | Differential role of caspase-8 and BID activation during radiation- and CD95-induced apoptosis |
Q47633429 | Differentiation-dependent sensitivity to apoptogenic factors in PC12 cells. |
Q27636617 | Dimer formation drives the activation of the cell death protease caspase 9 |
Q37845412 | Disintegration of the medial epithelial seam: is cell death important in palatogenesis? |
Q57272486 | Dissecting the apoptotic mechanisms of chemotherapeutic drugs and lymphocytes to design effective anticancer therapies |
Q51091938 | Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. |
Q33958788 | Distinct glucocorticoid receptor transcriptional regulatory surfaces mediate the cytotoxic and cytostatic effects of glucocorticoids |
Q46543702 | Distinct mechanisms of neuronal apoptosis are triggered by antagonism of Bcl-2/Bcl-x(L) versus induction of the BH3-only protein Bim. |
Q43882753 | Diversity of the apoptotic response to chemotherapy in childhood leukemia |
Q45267818 | Do inducers of apoptosis trigger caspase-independent cell death? |
Q34096352 | Drug discovery opportunities from apoptosis research |
Q48224018 | Dual behavior of N-acetylcysteine during ethanol-induced oxidative stress in embryonic chick brains. |
Q43275683 | Dual effect of glutamate on GABAergic interneuron survival during cerebral cortex development in mice neonates |
Q30865918 | Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions |
Q84971423 | Dynamics of caspase-3 activation and inhibition in embryonic micromasses evaluated by a photon-counting chemiluminescence approach |
Q34658574 | Dysregulation of apoptosis genes in hematopoietic malignancies. |
Q78968663 | ER stress induces caspase-8 activation, stimulating cytochrome c release and caspase-9 activation |
Q38905560 | Effect of chronic pesticide exposure on murine cornea: a histopathological, cytological and flow cytometric approach to study ocular damage by xenobiotics. |
Q77918828 | Effect of p21waf1/cip1 transgene on radiation induced apoptosis in T cells |
Q33924333 | Effective blockage of both the extrinsic and intrinsic pathways of apoptosis in mice by TAT-crmA |
Q38781385 | Effects of paclitaxel on permanent head and neck squamous cell carcinoma cell lines and identification of anti-apoptotic caspase 9b. |
Q48903959 | Elevated DNA double strand breaks and apoptosis in the CNS of scid mutant mice. |
Q47617801 | Embryonic neuronal death due to neurotrophin and neurotransmitter deprivation occurs independent of Apaf-1. |
Q33816829 | Endogenous inhibitors of caspases |
Q28206238 | Endonuclease G is an apoptotic DNase when released from mitochondria |
Q91941027 | Endoplasmic reticulum and Golgi stress in microcephaly |
Q52577797 | Endoplasmic reticulum stress-induced death of mouse embryonic fibroblasts requires the intrinsic pathway of apoptosis. |
Q44173100 | Enrichment of LDL with EPA and DHA decreased oxidized LDL-induced apoptosis in U937 cells |
Q36473607 | EphA/ephrin-A signaling is critically involved in region-specific apoptosis during early brain development |
Q28594694 | Epistatic and independent functions of caspase-3 and Bcl-X(L) in developmental programmed cell death |
Q35964742 | Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity |
Q36702308 | Essential role of grim-led programmed cell death for the establishment of corazonin-producing peptidergic nervous system during embryogenesis and metamorphosis in Drosophila melanogaster |
Q28209183 | Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death |
Q30408769 | Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. |
Q48599767 | Evidence that caspase-1 is a negative regulator of AMPA receptor-mediated long-term potentiation at hippocampal synapses. |
Q28258984 | Evolution of the neocortex: a perspective from developmental biology |
Q34764065 | Evolving concepts of cortical radial and areal specification |
Q28504797 | Ex vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart |
Q33656126 | Excitotoxins in neuronal apoptosis and necrosis |
Q34146813 | Executionary pathway for apoptosis: lessons from mutant mice |
Q27303642 | Executioner Caspase-3 and 7 Deficiency Reduces Myocyte Number in the Developing Mouse Heart |
Q44132582 | Exogenous smac induces competence and permits caspase activation in sympathetic neurons. |
Q28219614 | Expression analysis of a novel p75(NTR) signaling protein, which regulates cell cycle progression and apoptosis |
Q51425342 | Expression of Fas, FasL, caspase-8 and other factors of the extrinsic apoptotic pathway during the onset of interdigital tissue elimination. |
Q40781435 | Extended polyglutamine selectively interacts with caspase-8 and -10 in nuclear aggregates |
Q40794689 | FGF induces a switch in death receptor pathways in neuronal cells. |
Q42150350 | Failure to complete apoptosis following neonatal hypoxia-ischemia manifests as "continuum" phenotype of cell death and occurs with multiple manifestations of mitochondrial dysfunction in rodent forebrain |
Q42132563 | Fas-Activated Mitochondrial Apoptosis Culls Stalled Embryonic Stem Cells to Promote Differentiation |
Q35253620 | Fas-associated factor 1 as a regulator of olfactory axon guidance |
Q28589482 | Fgf10 regulates transition period of cortical stem cell differentiation to radial glia controlling generation of neurons and basal progenitors |
Q35152994 | Fine-tuning of neurogenesis is essential for the evolutionary expansion of the cerebral cortex |
Q42504826 | Focal adhesion kinase mediates cell survival via NF-kappaB and ERK signaling pathways. |
Q34098735 | Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1. |
Q41702049 | Formation of cortical fields on a reduced cortical sheet. |
Q43830916 | Formation of the Apaf-1/cytochrome c complex precedes activation of caspase-9 during seizure-induced neuronal death |
Q37424995 | Fumigaclavine C from a marine-derived fungus Aspergillus fumigatus induces apoptosis in MCF-7 breast cancer cells. |
Q33558259 | Functional cooperation of the proapoptotic Bcl2 family proteins Bmf and Bim in vivo |
Q90485436 | Functional integration of "undead" neurons in the olfactory system |
Q45875109 | Functions of the AP-2α gene in activating apoptosis and inhibiting proliferation of gastric cancer cells both in vitro and in vivo |
Q36326358 | GPER agonist G-1 decreases adrenocortical carcinoma (ACC) cell growth in vitro and in vivo |
Q33713375 | Gene targeting in the analysis of mammalian apoptosis and TNF receptor superfamily signaling |
Q30657334 | Gene trap: a way to identify novel genes and unravel their biological function |
Q43809110 | Generation of a constitutively active fragment of PKN in microglia/macrophages after middle cerebral artery occlusion in rats |
Q44658237 | Generation of retinal ganglion cells is modulated by caspase-dependent programmed cell death |
Q34170792 | Genetic analysis of apoptotic and survival signals |
Q34540789 | Genetic analysis of the mammalian cell death machinery |
Q37158051 | Genetic causes of microcephaly and lessons for neuronal development |
Q51864092 | Genetic inhibition of caspase-2 reduces hypoxic-ischemic and excitotoxic neonatal brain injury. |
Q33713368 | Genetic models of abnormal apoptosis in lymphocytes |
Q48173288 | Genetic screening and functional analysis of CASP9 mutations in a Chinese cohort with neural tube defects. |
Q34552276 | Genetics and development of neural tube defects. |
Q34250267 | Genetics of central nervous system developmental disorders. |
Q60960849 | Genomic mosaicism in the developing and adult brain |
Q37542684 | Glucocorticoid Induced Cerebellar Toxicity in the Developing Neonate: Implications for Glucocorticoid Therapy during Bronchopulmonary Dysplasia |
Q35043097 | Glucocorticoid receptor stimulation and the regulation of neonatal cerebellar neural progenitor cell apoptosis |
Q35831218 | Glucocorticoid-induced apoptosis and glucocorticoid resistance: molecular mechanisms and clinical relevance. |
Q36628641 | Glucocorticoid-induced apoptosis of healthy and malignant lymphocytes |
Q36325611 | Glucocorticoids in T cell apoptosis and function. |
Q44590966 | Glutathione Peroxidase Overexpression Inhibits CytochromecRelease and Proapoptotic Mediators to Protect Neurons From Experimental Stroke |
Q40837904 | Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition |
Q28655454 | Growth and folding of the mammalian cerebral cortex: from molecules to malformations |
Q35685294 | Growth and guidance cues for regenerating axons: where have they gone? |
Q24618872 | Guidance molecules in axon pruning and cell death |
Q39979531 | HDAC4 inhibits cell-cycle progression and protects neurons from cell death |
Q36768058 | HSF-1 activates the ubiquitin proteasome system to promote non-apoptotic developmental cell death in C. elegans. |
Q51988213 | HSP110, caspase-3 and -9 expression in physiological apoptosis and apoptosis induced by in vivo embryonic exposition to all-trans retinoic acid or irradiation during early mouse eye development. |
Q38834715 | HSP70 mediates survival in apoptotic cells-Boolean network prediction and experimental validation |
Q52316687 | HSP90 inhibition targets autophagy and induces a CASP9-dependent resistance mechanism in NSCLC. |
Q44283578 | Head size constrains forebrain development and evolution in ray-finned fishes |
Q73177747 | Hidden powers of the mitochondria |
Q81494058 | Histological analyses of normally grown, fertile Apaf1-deficient mice |
Q48119260 | Histology Atlas of the Developing Prenatal and Postnatal Mouse Central Nervous System, with Emphasis on Prenatal Days E7.5 to E18.5. |
Q33992348 | Hormonal regulation of physiological cell turnover and apoptosis |
Q34931816 | How death shapes life during development |
Q49922823 | How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression? |
Q24631607 | How to form and close the brain: insight into the mechanism of cranial neural tube closure in mammals |
Q24534085 | Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis |
Q48091564 | Human brain of preterm infants after hypoxic-ischaemic injuries: no evidence of a substantial role for apoptosis by using a fine-tuned ultrasound-guided neuropathological analysis |
Q57839949 | Huntingtin proteolysis in Huntington disease |
Q73082173 | Hydrogen peroxide inhibits activation, not activity, of cellular caspase-3 in vivo |
Q79991488 | Hypoxia-induced cell death and activation of pro- and anti-apoptotic proteins in developing chick optic lobe |
Q24804177 | Hypoxia-mediated apoptosis in oral carcinoma cells occurs via two independent pathways |
Q33770270 | Hypoxic-ischemic encephalopathy in the term infant |
Q73978686 | IGF-I receptor activation and BCL-2 overexpression prevent early apoptotic events in human neuroblastoma |
Q51954200 | IL-9/IL-9 receptor signaling selectively protects cortical neurons against developmental apoptosis. |
Q39754898 | Identification of a 'genuine' mammalian homolog of nematodal CED-4: is the hunt over or do we need better guns? |
Q40784940 | Identification of a caspase-9 substrate and detection of its cleavage in programmed cell death during mouse development |
Q37415041 | Identification of neural programmed cell death through the detection of DNA fragmentation in situ and by PCR. |
Q87904878 | Identification of transcripts potentially involved in neural tube closure using RNA sequencing |
Q54389891 | Immune clearance gastric carcinoma cells in ascites by activating caspase-9-induced apoptosis. |
Q35195215 | Immune disorders caused by defects in the caspase cascade |
Q35145656 | In vivo cellular and molecular mechanisms of neuronal apoptosis in the mammalian CNS. |
Q44247683 | In vivo role of caspases in excitotoxic neuronal death: generation and analysis of transgenic mice expressing baculoviral caspase inhibitor, p35, in postnatal neurons |
Q28507997 | Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis |
Q28580707 | Inactivation of farnesyltransferase and geranylgeranyltransferase I by caspase-3: cleavage of the common alpha subunit during apoptosis |
Q46175954 | Increased cell proliferation and granule cell number in the dentate gyrus of protein repair-deficient mice |
Q79696856 | Increased proliferation of CD8+ T cells in SAP-deficient mice is associated with impaired activation-induced cell death |
Q28755819 | Incudomalleal joint formation: the roles of apoptosis, migration and downregulation |
Q28272882 | Induced inhibition of ischemic/hypoxic injury by APIP, a novel Apaf-1-interacting protein |
Q28114555 | Induction of Expansion and Folding in Human Cerebral Organoids |
Q35043420 | Induction of apoptosis in cancer: new therapeutic opportunities |
Q44382910 | Induction of apoptosis in fetal pulmonary arterial smooth muscle cells by a combined superoxide dismutase/catalase mimetic |
Q46375880 | Induction of cell death in rat small intestine by ischemia reperfusion: differential roles of Fas/Fas ligand and Bcl-2/Bax systems depending upon cell types |
Q45405226 | Induction of immature dendritic cell apoptosis by foot and mouth disease virus is an integrin receptor mediated event before viral infection. |
Q22010404 | Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II |
Q33890314 | Inhibition of apoptosis and clonogenic survival of cells expressing crmA variants: optimal caspase substrates are not necessarily optimal inhibitors |
Q46542928 | Inhibition of apoptosome activation protects injured motor neurons from cell death |
Q42800979 | Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK. |
Q44131363 | Inhibition of caspases protects cerebellar granule cells of the weaver mouse from apoptosis and improves behavioral phenotype. |
Q40943846 | Inhibition of virus-induced neuronal apoptosis by Bax. |
Q40724758 | Inhibitor specificity of recombinant and endogenous caspase-9. |
Q37174527 | Inhibitory effect of PACAP on caspase activity in neuronal apoptosis: a better understanding towards therapeutic applications in neurodegenerative diseases. |
Q34223547 | Inositol 1,3,4-trisphosphate 5/6-kinase inhibits tumor necrosis factor-induced apoptosis |
Q64448633 | Insights into T-Cell Development from Studies Using Transgenic and Knockout Mice |
Q53371634 | Insulin-like growth factor-1 inhibits 6-hydroxydopamine-mediated endoplasmic reticulum stress-induced apoptosis via regulation of heme oxygenase-1 and Nrf2 expression in PC12 cells. |
Q44205869 | Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons. |
Q33748270 | Integrated genomics of susceptibility to alkylator-induced leukemia in mice |
Q48198830 | Interaction between XIAP and Smac/DIABLO in the mouse brain after transient focal cerebral ischemia |
Q37845411 | Interdigital cell death function and regulation: new insights on an old programmed cell death model |
Q26859279 | Interkinetic nuclear migration generates and opposes ventricular-zone crowding: insight into tissue mechanics |
Q90781282 | Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development |
Q36604805 | Interplay between the p53 tumor suppressor protein family and Cdk5: novel therapeutic approaches for the treatment of neurodegenerative diseases using selective Cdk inhibitors |
Q73472953 | Intracerebral injection of caspase-3 inhibitor prevents neuronal apoptosis after kainic acid-evoked status epilepticus |
Q34490979 | Involvement of mitochondria in apoptosis |
Q40047545 | Involvement of mitochondria-caspase pathway in Hemoporfin-mediated cell death |
Q44391043 | Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice |
Q36375843 | Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy |
Q43722438 | Ionizing radiation but not anticancer drugs causes cell cycle arrest and failure to activate the mitochondrial death pathway in MCF-7 breast carcinoma cells |
Q43583342 | Irradiation of mitochondria initiates apoptosis in a cell free system |
Q34293956 | Is caspase-3 inhibition a valid therapeutic strategy in cerebral ischemia? |
Q36016453 | Iso-suillin from Suillus flavus Induces Apoptosis in Human Small Cell Lung Cancer H446 Cell Line |
Q37947994 | It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival |
Q34305683 | Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo. |
Q28764730 | Karl Pribram, The James Arthur lectures, and what makes us human |
Q49865560 | Key apoptotic genes APAF1 and CASP9 implicated in recurrent folate-resistant neural tube defects. |
Q31926029 | Key targets for the execution of radiation-induced tumor cell apoptosis: the role of p53 and caspases |
Q37848690 | Kidney and urinary tract development: an apoptotic balancing act. |
Q38009194 | Killing a cancer: what are the alternatives? |
Q33354609 | Laminin enhances the growth of human neural stem cells in defined culture media |
Q34282245 | Laminin regulates postnatal oligodendrocyte production by promoting oligodendrocyte progenitor survival in the subventricular zone |
Q33257222 | Laser scanning cytometry in the characterization of the proapoptotic effects of transiently transfected genes in cerebellar granule neurons |
Q47373804 | Less is more: progenitor death and cortical size |
Q34097412 | Live imaging of apoptosis in a novel transgenic mouse highlights its role in neural tube closure. |
Q34046206 | Live or let die - retinal ganglion cell death and survival during development and in the lesioned adult CNS. |
Q36658110 | Loss of Gli3 enhances the viability of embryonic telencephalic cells in vitro. |
Q35641895 | Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death |
Q37128350 | Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse |
Q40245914 | Loss of caspase-9 provides genetic evidence for the type I/II concept of CD95-mediated apoptosis |
Q40213057 | Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membrane depolarization |
Q53926583 | Loss of drug-induced activation of the CD95 apoptotic pathway in a cisplatin-resistant testicular germ cell tumor cell line. |
Q33928666 | Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development. |
Q48633296 | Loss of notch activity in the developing central nervous system leads to increased cell death. |
Q41776106 | Low oxygen enhances primitive and definitive neural stem cell colony formation by inhibiting distinct cell death pathways |
Q33796094 | Lysosome dysfunction triggers Atg7-dependent neural apoptosis |
Q36302900 | Mammalian initiator apoptotic caspases |
Q44844420 | Manganese Superoxide Dismutase Affects Cytochrome c Release and Caspase-9 Activation After Transient Focal Cerebral Ischemia in Mice |
Q90440542 | Maternal vitamin B12 deficiency in rats alters DNA methylation in metabolically important genes in their offspring |
Q43066434 | Mathematical modeling supports substantial mouse neural progenitor cell death |
Q34067880 | Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity |
Q58553823 | Mcl-1 and Bcl-xL are essential for survival of the developing nervous system |
Q43128865 | Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage |
Q38059700 | Mdm2 and MdmX as Regulators of Gene Expression |
Q40531082 | Mechanism of Fas-mediated cell death and its enhancement by TNF-alpha in human salivary gland adenocarcinoma cell line HSG. |
Q30832096 | Mechanism of action for N-substituted benzamide-induced apoptosis |
Q48290587 | Mechanism of activation of caspase-9 and caspase-3 during hypoxia in the cerebral cortex of newborn piglets: the role of nuclear Ca2+ -influx |
Q36197618 | Mechanism of caspase-9 activation during hypoxia in the cerebral cortex of newborn piglets: the role of Src kinase |
Q34022496 | Mechanism of tyrosine phosphorylation of procaspase-9 and Apaf-1 in cytosolic fractions of the cerebral cortex of newborn piglets during hypoxia |
Q37943258 | Mechanisms and pathways of growth failure in primordial dwarfism. |
Q42611206 | Mechanisms of T-cell Apoptosis Induced by Glucocorticoids |
Q56609201 | Mechanisms of apoptosis |
Q73544921 | Mechanisms of apoptosis in embryonic cortical neurons (E6 and E7) in culture involve lipid signalling, protein phosphorylation and caspase activation |
Q35120707 | Mechanisms of cytochrome c release by proapoptotic BCL-2 family members |
Q36398098 | Mechanisms of early brain injury after subarachnoid hemorrhage |
Q36045199 | Mechanisms of neural cell death: implications for development of neuroprotective treatment strategies |
Q27919627 | Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases |
Q33944933 | Mechanisms of programmed cell death in the developing brain |
Q37341018 | Mechanisms regulating the susceptibility of hematopoietic malignancies to glucocorticoid-induced apoptosis |
Q33935219 | Mechanisms underlying hypoxia-induced neuronal apoptosis |
Q38969211 | Metabolic Regulation of Apoptosis in Cancer. |
Q35190373 | MicroRNA gene expression signatures in the developing neural tube |
Q50326592 | MicroRNA-132 protects hippocampal neurons against oxygen-glucose deprivation-induced apoptosis. |
Q24321570 | Microcephaly with simplified gyration, epilepsy, and infantile diabetes linked to inappropriate apoptosis of neural progenitors |
Q34649089 | Microglia regulate the number of neural precursor cells in the developing cerebral cortex |
Q33816824 | Mitochondria and apoptosis: HQ or high-security prison? |
Q90859789 | Mitochondria as multifaceted regulators of cell death |
Q46598275 | Mitochondria-dependent pathway is involved in heat-induced male germ cell death: lessons from mutant mice |
Q38235124 | Mitochondria-mediated apoptosis in mammals |
Q55920332 | Mitochondrial activation of apoptosis |
Q37691346 | Mitochondrial control of caspase-dependent and -independent cell death |
Q48847340 | Mitochondrial dysfunction and oxidative stress as determinants of cell death/survival in stroke. |
Q44636686 | Mitochondrial dysfunction in CD47-mediated caspase-independent cell death: ROS production in the absence of cytochrome c and AIF release |
Q37526353 | Mitochondrial membrane permeabilization in neuronal injury |
Q47073934 | Modulation of p53 and met expression by Krüppel-like factor 8 regulates zebrafish cerebellar development |
Q42792442 | Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis |
Q35046100 | Molecular determinants of glucocorticoid sensitivity and resistance in acute lymphoblastic leukemia |
Q35469289 | Molecular mechanism of size control in development and human diseases |
Q37027281 | Molecular mechanisms of apoptosis in cerebral ischemia: multiple neuroprotective opportunities |
Q43825779 | Molecular mechanisms of apoptosis induced by magnolol in colon and liver cancer cells |
Q36033294 | Molecular mechanisms of glucocorticoids in the control of inflammation and lymphocyte apoptosis |
Q48356347 | Molecular mechanisms of neuronal death in the dorsal lateral geniculate nucleus following visual cortical lesions. |
Q30306313 | Molecular pathway of germ cell apoptosis following ischemia/reperfusion of the rat testis |
Q47628054 | Molecular requirements for the combined effects of TRAIL and ionising radiation |
Q37134181 | Morphological characteristics of apoptosis and its significance in neurogenesis |
Q63408387 | Mostly dead |
Q35027903 | Motor neuron trophic factors: therapeutic use in ALS? |
Q74014346 | Mouse mammary gland involution is associated with cytochrome c release and caspase activation |
Q34266817 | Mouse models of cell death |
Q34326024 | Multiple functions of BCL-2 family proteins |
Q34608399 | Mutational analysis of the Caenorhabditis elegans cell-death gene ced-3. |
Q37396889 | Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly with a Rare Lissencephaly Variant |
Q47131885 | Myocardin and Stat3 act synergistically to inhibit cardiomyocyte apoptosis |
Q24554454 | NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis |
Q35202849 | Nature versus nurture revisited: an old idea with a new twist |
Q64814767 | Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases |
Q54981573 | Necroptosis in development and diseases. |
Q39044997 | Necroptosis in development, inflammation and disease. |
Q33782491 | Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling |
Q34565433 | Neural stem cells and regulation of cell number |
Q30441111 | Neural-specific inactivation of ShcA results in increased embryonic neural progenitor apoptosis and microencephaly. |
Q87906376 | Neuronal Cell Death |
Q37644193 | Neuronal caspase-3 signaling: not only cell death |
Q33547888 | Neuronal cell death: a demise with different shapes. |
Q36045204 | Neuronal death/survival signaling pathways in cerebral ischemia |
Q34201997 | Neuronal life and death: an essential role for the p53 family |
Q34687686 | Neurons bearing presenilins: weapons for defense or suicide? |
Q34119497 | Neuroprotection by caspase inhibitors |
Q30857660 | Neuroprotection by the inhibition of apoptosis |
Q34083682 | Neurotransmitters and apoptosis in the developing brain |
Q37998778 | Neurotrophins and cell death. |
Q92363377 | New insights into the development of the human cerebral cortex |
Q27011322 | New roles for old enzymes: killer caspases as the engine of cell behavior changes |
Q34305204 | Nitric oxide-induced apoptosis in tumor cells |
Q22010046 | Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB |
Q39140585 | Non-apoptotic cell death in animal development |
Q37695139 | Non-caspase proteases: triggers or amplifiers of apoptosis? |
Q37147746 | Noncanonical cell death programs in the nematode Caenorhabditis elegans |
Q34301992 | Normal immune development and glucocorticoid-induced thymocyte apoptosis in mice deficient for the T-cell death-associated gene 8 receptor. |
Q42823834 | Notch promotes survival of neural precursor cells via mechanisms distinct from those regulating neurogenesis. |
Q34126046 | Nuclear hormone receptors in T lymphocytes |
Q46921316 | Nuclear progesterone receptor A and B isoforms in mouse fallopian tube and uterus: implications for expression, regulation, and cellular function |
Q47793462 | Nuclear translocation of cytochrome c during apoptosis. |
Q28472140 | ON/OFF and beyond--a boolean model of apoptosis |
Q54410209 | Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells. |
Q59783959 | Oligodendrocyte apoptosis mediated by caspase activation |
Q39666776 | Optimizing photodynamic therapy by liposomal formulation of the photosensitizer pyropheophorbide-a methyl ester: In vitro and ex vivo comparative biophysical investigations in a colon carcinoma cell line |
Q40850451 | Ordering of ceramide formation, caspase activation, and mitochondrial changes during CD95- and DNA damage-induced apoptosis |
Q22008727 | Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner |
Q36696631 | Organ size control by Hippo and TOR pathways. |
Q39059494 | Organotypic slice cultures for analysis of proliferation, cell death, and migration in the embryonic neocortex |
Q40185578 | Overexpression of caspase-9 triggers its activation and apoptosis in vitro. |
Q43833745 | Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation. |
Q57173169 | Overexpression of retinoblastoma‑binding protein 4 contributes to the radiosensitivity of AGS gastric cancer cells via phosphoinositide3‑kinase/protein kinase B pathway suppression |
Q74341665 | Oxidative stress and apoptosis |
Q36161829 | Oxidative stress and neuronal death/survival signaling in cerebral ischemia |
Q28084613 | Oxidative stress, unfolded protein response, and apoptosis in developmental toxicity |
Q29619852 | Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis |
Q79881731 | Parthenolide protects human lens epithelial cells from oxidative stress-induced apoptosis via inhibition of activation of caspase-3 and caspase-9 |
Q36961965 | Pathophysiological Significance of Hepatic Apoptosis |
Q37631575 | Pathophysiology and the Monitoring Methods for Cardiac Arrest Associated Brain Injury |
Q37574787 | Pathophysiology of acute kidney injury |
Q36166503 | Pathways of apoptosis and importance in development. |
Q47074392 | Peroxisome proliferator-activated receptor-γ enhances human pulmonary artery smooth muscle cell apoptosis through microRNA-21 and programmed cell death 4. |
Q33601950 | Perspective: virus infections and the death of neurons |
Q93052161 | Phagocytosis of Necrotic Debris at Sites of Injury and Inflammation |
Q39696436 | Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest. |
Q26853192 | Photoreceptor cell death and rescue in retinal detachment and degenerations |
Q34147269 | Physiological and pathological caspase cleavage of the neuronal RasGEF GRASP-1 as detected using a cleavage site-specific antibody |
Q44401713 | Pituitary adenylate cyclase‐activating polypeptide prevents C2‐ceramide‐induced apoptosis of cerebellar granule cells |
Q51548450 | Placental bed apoptosis is increased in pregnant women with pre-eclampsia versus normotensive pregnant women. |
Q42055819 | Plasmatocytes from the moth Pseudoplusia includens induce apoptosis of granular cells |
Q33390267 | Platelet-derived growth factor enhances platelet recovery in a murine model of radiation-induced thrombocytopenia and reduces apoptosis in megakaryocytes via its receptors and the PI3-k/Akt pathway |
Q34054886 | Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies. |
Q48179334 | Postnatal distribution of cpp32/caspase 3 mRNA in the mouse central nervous system: an in situ hybridization study |
Q43861757 | Pre-processed caspase-9 contained in mitochondria participates in apoptosis |
Q73616626 | Prediction of the tertiary structure of a caspase-9/inhibitor complex |
Q43569874 | Preliminary evaluation of caspases-dependent apoptosis signaling pathways of free and HPMA copolymer-bound doxorubicin in human ovarian carcinoma cells |
Q36328615 | Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release |
Q36392288 | Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis. |
Q30865931 | Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L). |
Q24298402 | Proapoptotic BAX and BAK control multiple initiator caspases |
Q28363890 | Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death |
Q42378443 | Proapoptotic function of deubiquitinase DUSP31 in Drosophila. |
Q37845409 | Programmed cell death during postnatal development of the rodent nervous system |
Q52118783 | Programmed cell death in the neurulating embryo is prevented by the chaperone heat shock cognate 70. |
Q48829797 | Programmed cell death of developing mammalian neurons after genetic deletion of caspases. |
Q36316322 | Programmed cell death of embryonic motoneurons triggered through the Fas death receptor |
Q34303405 | Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis |
Q34747476 | Proliferation and apoptosis in the developing human neocortex. |
Q39268374 | Promotion of Caspase Activation by Caspase-9-mediated Feedback Amplification of Mitochondrial Damage |
Q38663181 | Protease signaling in animal and plant-regulated cell death |
Q33927179 | Proteases for cell suicide: functions and regulation of caspases |
Q52537613 | Proteasome inhibitors induce cytochrome c-caspase-3-like protease-mediated apoptosis in cultured cortical neurons. |
Q46319973 | Proteasome-mediated degradation of Tob is pivotal for triggering UV-induced apoptosis |
Q40735912 | Protective effects of anti-C5a in sepsis-induced thymocyte apoptosis |
Q33410395 | Protein evolution on a human signaling network |
Q64092700 | Qiliqiangxin Capsule Improves Cardiac Function and Attenuates Cardiac Remodeling by Upregulating miR-133a after Myocardial Infarction in Rats |
Q57802350 | RAB-35 and ARF-6 GTPases Mediate Engulfment and Clearance Following Linker Cell-Type Death |
Q37251495 | REVIEW paper: pathophysiology of myocardial reperfusion injury: the role of genetically engineered mouse models |
Q33552631 | RNA interference-mediated downregulation of Beclin1 attenuates cerebral ischemic injury in rats |
Q41772077 | Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly |
Q49910228 | Rare mutations inapoptosis related genes APAF1, CASP9, and CASP3 contribute to human neural tube defects. |
Q35568820 | Reactive Oxygen Radicals and Pathogenesis of Neuronal Death After Cerebral Ischemia |
Q75233308 | Reactive oxygen species regulate quiescent T-cell apoptosis via the BH3-only proapoptotic protein BIM |
Q33535174 | Rearranging views on neurogenesis: neuronal death in the absence of DNA end-joining proteins |
Q35036503 | Recent advances in amyotrophic lateral sclerosis research |
Q34502160 | Recent insights into the mechanism of glucocorticosteroid-induced apoptosis |
Q28354545 | Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes |
Q73088831 | Reduction of endogenous transforming growth factors beta prevents ontogenetic neuron death |
Q36092826 | Redundant cell death mechanisms as relics and backups |
Q24321468 | Regulation of XIAP translation and induction by MDM2 following irradiation |
Q39890975 | Regulation of caspase 9 through phosphorylation by protein kinase C zeta in response to hyperosmotic stress |
Q33606109 | Regulation of caspase activation in apoptosis: implications in pathogenesis and treatment of disease |
Q24675830 | Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide |
Q34117899 | Regulation of death receptor-mediated apoptosis pathways |
Q24673747 | Regulation of lymphocyte apoptosis by interferon regulatory factor 4 (IRF-4) |
Q35743096 | Regulation of the apoptosis-necrosis switch |
Q52564437 | Regulation of the expression of tumor necrosis factor‑related genes by abnormal histone H3K27 acetylation: Implications for neural tube defects. |
Q36368602 | Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia |
Q43960599 | Release of cytochrome c into the extracellular space contributes to neuronal apoptosis induced by staurosporine |
Q30512263 | Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice |
Q40634325 | Ribosome-inactivating protein and apoptosis: abrin causes cell death via mitochondrial pathway in Jurkat cells |
Q24632980 | Ripped to death |
Q43658606 | Role of DNA-dependent protein kinase in neuronal survival. |
Q36934716 | Role of Smac/DIABLO in cancer progression |
Q54059288 | Role of c-jun expression increased by heat shock- and ceramide-activated caspase-3 in HL-60 cell apoptosis. Possible involvement of ceramide in heat shock-induced apoptosis. |
Q43937484 | Role of caspase-3 activation in cerebral ischemia-induced neurodegeneration in adult and neonatal brain |
Q40185447 | Role of cytochrome C in apoptosis: increased sensitivity to tumor necrosis factor alpha is associated with respiratory defects but not with lack of cytochrome C release |
Q90593452 | Role of cytochrome c in modulating chromium-induced oxidative stress in Oryza sativa |
Q35212533 | Role of factors downstream of caspases in nuclear disassembly during apoptotic execution. |
Q41924709 | Role of founder cell deficit and delayed neuronogenesis in microencephaly of the trisomy 16 mouse. |
Q37030395 | Role of intermediate progenitor cells in cerebral cortex development |
Q25257246 | Role of mechanical factors in the morphology of the primate cerebral cortex |
Q33955146 | Role of neurotrophin receptor p75NTR in mediating neuronal cell death following injury |
Q36000508 | Role of programmed cell death in normal neuronal development and function |
Q35085408 | Roles of the mammalian subventricular zone in brain development |
Q45230294 | Rotenone-induced caspase 9/3-independent and -dependent cell death in undifferentiated and differentiated human neural stem cells. |
Q40602856 | S-Nitrosation regulates the activation of endogenous procaspase-9 in HT-29 human colon carcinoma cells |
Q91816871 | Seasonal Variations in the Chemical Composition of Liangshan Olive Leaves and Their Antioxidant and Anticancer Activities |
Q34212502 | Selected comparison of immune and nervous system development |
Q28567192 | Selective GPER activation decreases proliferation and activates apoptosis in tumor Leydig cells |
Q53343723 | Selective and protracted apoptosis in human primary neurons microinjected with active caspase-3, -6, -7, and -8. |
Q59393051 | Selective inhibitors of apoptotic caspases: implications for novel therapeutic strategies |
Q41476953 | Selective uptake of epidermal growth factor-conjugated gold nanoparticle (EGF-GNP) facilitates non-thermal plasma (NTP)-mediated cell death |
Q55475629 | Sensitization to CD95 ligand-induced apoptosis in human glioma cells by hyperthermia involves enhanced cytochrome c release. |
Q53586139 | Serine protease Omi/HtrA2 targets WARTS kinase to control cell proliferation. |
Q73984950 | Serum-free induced neuronal apoptosis-like cell death is independent of caspase activity |
Q35083240 | Sexual dimorphism in ischemic stroke: lessons from the laboratory |
Q33289241 | Signal transducer and activator of transcription 3 is involved in cell growth and survival of human rhabdomyosarcoma and osteosarcoma cells |
Q28142592 | Signal transduction by the JNK group of MAP kinases |
Q34731231 | Signaling for survival and apoptosis in the immune system |
Q33793237 | Signaling of neuronal cell death by the p75NTR neurotrophin receptor |
Q34563012 | Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas. |
Q91651911 | Silencing of microRNA-146a alleviates the neural damage in temporal lobe epilepsy by down-regulating Notch-1 |
Q92525864 | Siva plays a critical role in mouse embryonic development |
Q39714230 | Smac/DIABLO release from mitochondria and XIAP inhibition are essential to limit clonogenicity of Type I tumor cells after TRAIL receptor stimulation |
Q34788518 | Soluble CPG15 expressed during early development rescues cortical progenitors from apoptosis |
Q27619762 | Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: a structural basis for specific adaptor/caspase interaction |
Q51687898 | Spatial growth of real-world networks. |
Q42916419 | Spatio-temporal activation of caspase revealed by indicator that is insensitive to environmental effects |
Q43514142 | Sphingosine 1-phosphate protects human umbilical vein endothelial cells from serum-deprived apoptosis by nitric oxide production |
Q49106082 | Staurosporine- and H-7-induced cell death in SH-SY5Y neuroblastoma cells is associated with caspase-2 and caspase-3 activation, but not with activation of the FAS/FAS-L-caspase-8 signaling pathway. |
Q48524880 | Strain-dependent neurodevelopmental abnormalities in caspase-3-deficient mice. |
Q24290945 | Structural basis for the inhibition of caspase-3 by XIAP |
Q46536480 | Surviving the cytochrome seas. |
Q38837843 | Systematic synthesis of low-molecular weight fucoidan derivatives and their effect on cancer cells. |
Q41834899 | Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein |
Q40703254 | TGF-beta induces cell death in the oligodendroglial cell line OLI-neu |
Q34542205 | TNF ligands and receptors--a matter of life and death |
Q34565473 | TNF receptor subtype signalling: differences and cellular consequences |
Q28142549 | TNF-induced signaling in apoptosis |
Q39644786 | TNFalpha inhibits skeletal myogenesis through a PW1-dependent pathway by recruitment of caspase pathways. |
Q35624736 | TRAIL, Bim, and thymic-negative selection |
Q39753656 | TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO. |
Q33547792 | Targeted disruption of caspase genes in mice: what they tell us about the functions of individual caspases in apoptosis. |
Q89840958 | Targeting apoptotic caspases in cancer |
Q38626400 | Targeting neonatal ischemic brain injury with a pentapeptide-based irreversible caspase inhibitor |
Q34235924 | The (not necessarily) convoluted role of basal radial glia in cortical neurogenesis. |
Q28212977 | The Anti-apoptotic Effect of Notch-1 Requires p56 -dependent, Akt/PKB-mediated Signaling in T Cells |
Q34648882 | The Apaf-1 apoptosome: a large caspase-activating complex |
Q24316930 | The Apaf-1*procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer |
Q40885189 | The BH3 domain is required for caspase-independent cell death induced by Bax and oligomycin |
Q35591695 | The Bcl-2 family: roles in cell survival and oncogenesis. |
Q35031256 | The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions |
Q29614982 | The Bcl2 family: regulators of the cellular life-or-death switch |
Q36846541 | The CARD-carrying caspase Dronc is essential for most, but not all, developmental cell death in Drosophila |
Q35561587 | The CD95 type I/type II model |
Q36518331 | The Cellular Apoptosis Susceptibility Protein (CAS) Promotes Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis and Cell Proliferation |
Q28548450 | The Chromone Alkaloid, Rohitukine, Affords Anti-Cancer Activity via Modulating Apoptosis Pathways in A549 Cell Line and Yeast Mitogen Activated Protein Kinase (MAPK) Pathway |
Q44611170 | The DNA damage-induced decrease of Bcl-2 is secondary to the activation of apoptotic effector caspases |
Q48219557 | The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development |
Q33361879 | The Role of Proteases in Hippocampal Synaptic Plasticity: Putting Together Small Pieces of a Complex Puzzle |
Q37661170 | The Short Isoform of DNAJB6 Protects against 1-Methyl-4-phenylpridinium Ion-Induced Apoptosis in LN18 Cells via Inhibiting Both ROS Formation and Mitochondrial Membrane Potential Loss. |
Q39682487 | The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis |
Q33997832 | The apoptosome: heart and soul of the cell death machine |
Q33908341 | The ced-8 gene controls the timing of programmed cell deaths in C. elegans. |
Q37992385 | The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome |
Q28512628 | The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues |
Q35586726 | The control of cell number during central nervous system development in flies and mice |
Q41728640 | The cytosolic antioxidant copper/zinc-superoxide dismutase prevents the early release of mitochondrial cytochrome c in ischemic brain after transient focal cerebral ischemia in mice. |
Q36844137 | The effector caspases drICE and dcp-1 have partially overlapping functions in the apoptotic pathway in Drosophila |
Q52973758 | The effects of arctigenin on human rheumatoid arthritis fibroblast-like synoviocytes. |
Q45247601 | The effects of hormones of the hypothalamo-hypophyseal-adrenal, renin-angiotensin, and thyroid hormone systems on the formation of dyscirculatory encephalopathy |
Q90149948 | The essentials of developmental apoptosis |
Q47595678 | The evolution of cortical development: the synapsid-diapsid divergence. |
Q36799509 | The genomically mosaic brain: aneuploidy and more in neural diversity and disease |
Q40860042 | The interferon-induced protein kinase (PKR), triggers apoptosis through FADD-mediated activation of caspase 8 in a manner independent of Fas and TNF-alpha receptors. |
Q37152729 | The involvement of cell death and survival in neural tube defects: a distinct role for apoptosis and autophagy? |
Q51020805 | The latency-related gene encoded by bovine herpesvirus 1 can suppress caspase 3 and caspase 9 cleavage during productive infection. |
Q34466450 | The machinery of programmed cell death. |
Q35831981 | The mitochondrial death pathway: a promising therapeutic target in diseases |
Q36751667 | The molecular mechanisms that control function and death of effector CD4+ T cells |
Q34002897 | The most unkindest cut of all: on the multiple roles of mammalian caspases |
Q34555987 | The myc oncogene: MarvelouslY Complex |
Q36521923 | The p53 family in nervous system development and disease |
Q24301611 | The p53-inducible E3 ubiquitin ligase p53RFP induces p53-dependent apoptosis |
Q35618322 | The p75 neurotrophin receptor: multiple interactors and numerous functions |
Q24561863 | The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II) dependent oxygenase activity |
Q48733386 | The potential tumour suppressor role for caspase-9 (CASP9) in the childhood malignancy, neuroblastoma. |
Q38697013 | The preventive effects of taurine on neural tube defects through the Wnt/PCP-Jnk-dependent pathway |
Q36301514 | The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol |
Q35902423 | The protein structures that shape caspase activity, specificity, activation and inhibition |
Q36805936 | The radial edifice of cortical architecture: from neuronal silhouettes to genetic engineering |
Q28586611 | The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development |
Q41837258 | The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event |
Q33781254 | The role of apoptosis in normal and abnormal embryonic development |
Q44189407 | The role of caspases 9 and 9-short (9S) in death ligand- and drug-induced apoptosis in human astrocytoma cells |
Q33686145 | The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice. |
Q36602674 | The role of mitochondria in apoptosis*. |
Q34859478 | The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet. |
Q52623796 | The role of suboptimal mitochondrial function in vulnerability to post-traumatic stress disorder. |
Q36913767 | The role of sulfur dioxide in the regulation of mitochondrion-related cardiomyocyte apoptosis in rats with isopropylarterenol-induced myocardial injury |
Q52574307 | The third horseman takes wing. |
Q33334247 | The transcription factor Nfix is essential for normal brain development |
Q44278351 | The tyrosine kinase Lck is involved in regulation of mitochondrial apoptosis pathways. |
Q54078688 | The tyrosine kinase lck is required for CD95-independent caspase-8 activation and apoptosis in response to ionizing radiation. |
Q33816812 | Thymocyte apoptosis |
Q40783269 | Thymocytes selected for resistance to hydrogen peroxide show altered antioxidant enzyme profiles and resistance to dexamethasone-induced apoptosis |
Q46075225 | Thymosin β4 induces folding of the developing optic tectum in the chicken (Gallus domesticus). |
Q33881268 | Tissue-specific Bcl-2 protein partners in apoptosis: An ovarian paradigm |
Q35743127 | Toxic proteins released from mitochondria in cell death |
Q35209364 | Tracking death dealing by Fas and TRAIL in lymphatic neoplastic disorders: pathways, targets, and therapeutic tools |
Q34124193 | Transforming growth factor beta-dependent sequential activation of Smad, Bim, and caspase-9 mediates physiological apoptosis in gastric epithelial cells |
Q28592731 | Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector |
Q40300559 | Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells |
Q92617806 | Triptolide reduces proliferation and enhances apoptosis in drug-resistant human oral cancer cells |
Q39987469 | Tubocapsenolide A, a novel withanolide, inhibits proliferation and induces apoptosis in MDA-MB-231 cells by thiol oxidation of heat shock proteins. |
Q41764558 | Tumors acquire inhibitor of apoptosis protein (IAP)-mediated apoptosis resistance through altered specificity of cytosolic proteolysis |
Q34071248 | Tumour necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NF-kappaB. |
Q24804943 | Two discrete events, human T-cell leukemia virus type I Tax oncoprotein expression and a separate stress stimulus, are required for induction of apoptosis in T-cells |
Q34145910 | Two phylogenetic specializations in the human brain |
Q42048093 | Type I interferon gene transfer sensitizes melanoma cells to apoptosis via a target activity on mitochondrial function |
Q36538525 | UBE4B: a promising regulatory molecule in neuronal death and survival |
Q39445447 | Uncouplers of oxidative phosphorylation can enhance a Fas death signal |
Q94948758 | Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation |
Q38349516 | Upstream AUGs in embryonic proinsulin mRNA control its low translation level. |
Q44630766 | VEIDase is a principal caspase-like activity involved in plant programmed cell death and essential for embryonic pattern formation. |
Q33653453 | Viral modulation of the host response via crmA/SPI-2 expression. |
Q37396234 | Vital staining for cell death identifies Atg9a-dependent necrosis in developmental bone formation in mouse |
Q53294318 | Vitamin C protects against ethanol and PTZ-induced apoptotic neurodegeneration in prenatal rat hippocampal neurons. |
Q53245187 | What's in a name? Would that which we call death by any other name be less tragic? |
Q38577529 | Who lives and who dies: Role of apoptosis in quashing developmental errors |
Q36370019 | Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription |
Q39915491 | YAP regulates neural progenitor cell number via the TEA domain transcription factor |
Q40415909 | Zinc protects renal function during cadmium intoxication in the rat. |
Q43583209 | Zinc-mediated regulation of caspases activity: dose-dependent inhibition or activation of caspase-3 in the human Burkitt lymphoma B cells (Ramos). |
Q78019259 | [Apoptosis--what is it? Significance in coronary heart disease and myocardial infarct] |
Q73539952 | [Physicopathologic mechanisms and methods of analysis of cellular apoptosis] |
Q34462324 | beta-Cell death during progression to diabetes |
Q34519958 | p38 mitogen-activated protein kinase mediates the Fas-induced mitochondrial death pathway in CD8+ T cells. |
Q57288790 | p53 deletion rescues lethal microcephaly in a mouse model with neural stem cell abscission defects |
Q63408383 | p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation |
Q34305233 | p53-dependent apoptosis pathways. |
Q42454035 | p63 antagonizes p53 to promote the survival of embryonic neural precursor cells |
Q24290118 | tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c |
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