review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.18632/ONCOTARGET.15098 |
P8608 | Fatcat ID | release_m7vgj425gjbbjlm4rstmqryopm |
P932 | PMC publication ID | 5410359 |
P698 | PubMed publication ID | 28177918 |
P2093 | author name string | Yan Liu | |
Qiang Li | |||
Ting Zhao | |||
Ping Li | |||
Libin Zhou | |||
Pengcheng Zhang | |||
Xiongxiong Liu | |||
Xiaogang Zheng | |||
P2860 | cites work | Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1 | Q22010148 |
Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins | Q24290511 | ||
Mechanism of XIAP-mediated inhibition of caspase-9 | Q24296916 | ||
HBXIP functions as a cofactor of survivin in apoptosis suppression | Q24303423 | ||
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade | Q24311006 | ||
The Apaf-1*procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer | Q24316930 | ||
X-linked IAP is a direct inhibitor of cell-death proteases | Q24318710 | ||
c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage | Q24338416 | ||
A quantitative atlas of mitotic phosphorylation | Q24646817 | ||
Engineering a dimeric caspase-9: a re-evaluation of the induced proximity model for caspase activation | Q24798064 | ||
Dimer formation drives the activation of the cell death protease caspase 9 | Q27636617 | ||
A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis | Q28139969 | ||
Mechanisms of caspase activation | Q28187994 | ||
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis | Q28204205 | ||
Regulation of cell death protease caspase-9 by phosphorylation | Q28288607 | ||
Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes | Q28354545 | ||
Nucling recruits Apaf-1/pro-caspase-9 complex for the induction of stress-induced apoptosis | Q28513434 | ||
DNA damage-induced neural precursor cell apoptosis requires p53 and caspase 9 but neither Bax nor caspase 3 | Q28513460 | ||
Inducible apoptosis as a safety switch for adoptive cell therapy | Q29617710 | ||
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9 | Q29618617 | ||
Novel anti-apoptotic microRNAs 582-5p and 363 promote human glioblastoma stem cell survival via direct inhibition of caspase 3, caspase 9, and Bim. | Q30413140 | ||
S-Nitrosylation of mitochondrial caspases | Q30441958 | ||
Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9. | Q30797347 | ||
Overexpression of HAX-1 protects cardiac myocytes from apoptosis through caspase-9 inhibition | Q33251282 | ||
Clinical application of a systems model of apoptosis execution for the prediction of colorectal cancer therapy responses and personalisation of therapy. | Q50507805 | ||
Caspase 9 promoter polymorphisms and risk of primary lung cancer. | Q53597510 | ||
Inhibition of caspase-9 activity and Apaf-1 expression in cisplatin-resistant head and neck squamous cell carcinoma cells. | Q53811624 | ||
Polymorphisms of caspase 8 and caspase 9 gene and colorectal cancer susceptibility and prognosis. | Q54374974 | ||
Caspase 8 and caspase 9 gene polymorphisms and susceptibility to gastric cancer. | Q54379655 | ||
Effects of caspase-9 and survivin gene polymorphisms in pancreatic cancer risk and tumor characteristics. | Q54434279 | ||
Controlling programmed cell death with a cyclophilin-cyclosporin-based chemical inducer of dimerization | Q71824439 | ||
Nitric oxide inhibits apoptosis downstream of cytochrome C release by nitrosylating caspase 9 | Q77815886 | ||
Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry | Q79491768 | ||
Association between Caspase-9 promoter region polymorphisms and discogenic low back pain | Q82522458 | ||
An inducible caspase 9 safety switch can halt cell therapy-induced autoimmune disease | Q43527563 | ||
De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1. | Q43860697 | ||
The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development | Q43971025 | ||
XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis | Q44104444 | ||
Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer | Q44123699 | ||
Role of caspase-9 in the effector caspases and genome expressions, and growth of bovine skeletal myoblasts | Q44260481 | ||
Presentation of nitric oxide regulates monocyte survival through effects on caspase-9 and caspase-3 activation | Q44302132 | ||
SRp30a (ASF/SF2) regulates the alternative splicing of caspase-9 pre-mRNA and is required for ceramide-responsiveness | Q44917660 | ||
Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c. | Q45259224 | ||
Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis. | Q45295534 | ||
Cytochrome C and caspase-9 expression in Huntington's disease | Q45306362 | ||
HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia | Q45882160 | ||
The docking interaction of caspase-9 with ERK2 provides a mechanism for the selective inhibitory phosphorylation of caspase-9 at threonine 125. | Q46847481 | ||
Caspase 9 and caspase 8 gene polymorphisms and susceptibility to bladder cancer in north Indian population | Q47890688 | ||
CASP-9: A susceptibility locus for multiple sclerosis in Italy. | Q48025575 | ||
Long-term outcome after haploidentical stem cell transplant and infusion of T cells expressing the inducible caspase 9 safety transgene | Q33781162 | ||
TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer. | Q33951635 | ||
Regulation of the Apaf-1-caspase-9 apoptosome | Q34129476 | ||
hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing | Q34245430 | ||
Caspase activation: revisiting the induced proximity model | Q34328287 | ||
Adoptive T-cell therapy: adverse events and safety switches | Q34511623 | ||
Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome | Q34581367 | ||
Alternative splicing of caspase 9 is modulated by the phosphoinositide 3-kinase/Akt pathway via phosphorylation of SRp30a | Q34685905 | ||
microRNA-24a is required to repress apoptosis in the developing neural retina | Q34976201 | ||
SRSF1 regulates the alternative splicing of caspase 9 via a novel intronic splicing enhancer affecting the chemotherapeutic sensitivity of non-small cell lung cancer cells | Q35118687 | ||
Caspase-9 and APAF-1 form an active holoenzyme | Q35210359 | ||
Caspase-9 regulation: an update | Q35802114 | ||
Aberrant and alternative splicing in cancer | Q35936123 | ||
Synthetic activation of caspases: artificial death switches | Q36007918 | ||
Inhibition of caspase 9 and not caspase 8 mediated apoptosis may determine clinical response to chemotherapy in primary nodal diffuse large B-cell lymphomas | Q36117986 | ||
Wild-type and mutant p53 mediate cisplatin resistance through interaction and inhibition of active caspase-9 | Q36618628 | ||
hnRNP U enhances caspase-9 splicing and is modulated by AKT-dependent phosphorylation of hnRNP L | Q36708640 | ||
The apoptosome: signalling platform of cell death | Q36766418 | ||
Apoptosis and autophagy: Regulation of caspase-9 by phosphorylation. | Q37605158 | ||
The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome | Q37992385 | ||
HAX-1 inhibits apoptosis in prostate cancer through the suppression of caspase-9 activation | Q38839315 | ||
Bcl-2 family inhibition sensitizes human prostate cancer cells to docetaxel and promotes unexpected apoptosis under caspase-9 inhibition | Q38946336 | ||
Comparison of different suicide-gene strategies for the safety improvement of genetically manipulated T cells. | Q39408105 | ||
Regulation of caspase 9 through phosphorylation by protein kinase C zeta in response to hyperosmotic stress | Q39890975 | ||
DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine | Q39915098 | ||
A non-apoptotic role for caspase-9 in muscle differentiation | Q39924087 | ||
Phosphorylation of murine caspase-9 by the protein kinase casein kinase 2 regulates its cleavage by caspase-8. | Q39984111 | ||
Phosphorylation of caspase-9 by CDK1/cyclin B1 protects mitotic cells against apoptosis | Q40139701 | ||
Failure of activation of caspase-9 induces a higher threshold for apoptosis and cisplatin resistance in testicular cancer. | Q40675295 | ||
Caspase 9 is required for p53-dependent apoptosis and chemosensitivity in a human ovarian cancer cell line | Q40757141 | ||
Genetic modification of human T cells with CD20: a strategy to purify and lyse transduced cells with anti-CD20 antibodies | Q40773080 | ||
Caspase-9 can be activated without proteolytic processing | Q40966257 | ||
Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis | Q40968400 | ||
A caspase-9 variant missing the catalytic site is an endogenous inhibitor of apoptosis | Q40980300 | ||
Differential requirement for caspase 9 in apoptotic pathways in vivo. | Q41015558 | ||
Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety | Q41179125 | ||
Functional analysis of Fas signaling in vivo using synthetic inducers of dimerization | Q41187958 | ||
Nitric oxide and apoptosis: another paradigm for the double-edged role of nitric oxide | Q41688613 | ||
An inducible caspase 9 safety switch for T-cell therapy | Q41768001 | ||
Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation | Q41953436 | ||
p38alpha- and DYRK1A-dependent phosphorylation of caspase-9 at an inhibitory site in response to hyperosmotic stress | Q42456617 | ||
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK. | Q42800979 | ||
Administration of herpes simplex-thymidine kinase-expressing donor T cells with a T-cell-depleted allogeneic marrow graft | Q43513924 | ||
MicroRNA-23a antisense enhances 5-fluorouracil chemosensitivity through APAF-1/caspase-9 apoptotic pathway in colorectal cancer cells | Q43522938 | ||
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 14 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | transport protein | Q2111029 |
enzyme | Q8047 | ||
peptide | Q172847 | ||
P304 | page(s) | 23996-24008 | |
P577 | publication date | 2017-02-04 | |
2017-04-04 | |||
P1433 | published in | Oncotarget | Q1573155 |
P1476 | title | Caspase-9: structure, mechanisms and clinical application | |
P478 | volume | 8 |
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