scholarly article | Q13442814 |
P2093 | author name string | R S Morrison | |
H Xiang | |||
M D Johnson | |||
Y Kinoshita | |||
S Ghatan | |||
P2860 | cites work | Caspases: the executioners of apoptosis | Q24530218 |
Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract | Q28267110 | ||
Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis | Q28283313 | ||
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme | Q28287610 | ||
Bax involvement in p53-mediated neuronal cell death | Q28510439 | ||
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours | Q29547697 | ||
Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination | Q29614627 | ||
Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis | Q29614983 | ||
Caspases: killer proteases | Q29616315 | ||
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9 | Q29618617 | ||
ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase. | Q33887607 | ||
p53 facilitates pRb cleavage in IL-3-deprived cells: novel pro-apoptotic activity of p53. | Q33889024 | ||
Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme | Q34325458 | ||
Prevention of vertebrate neuronal death by the crmA gene | Q34349314 | ||
Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice | Q34408475 | ||
Defects in regulation of apoptosis in caspase-2-deficient mice | Q35198808 | ||
Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage | Q36030783 | ||
Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death | Q36236941 | ||
Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases | Q36237706 | ||
Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons | Q36256866 | ||
Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death. | Q36273925 | ||
Proteolysis and the biochemistry of life-or-death decisions | Q36366734 | ||
Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury | Q36376859 | ||
Growth of purified astrocytes in a chemically defined medium | Q36380669 | ||
Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression | Q36551292 | ||
Activation of a caspase 3-related cysteine protease is required for glutamate-mediated apoptosis of cultured cerebellar granule neurons | Q36605145 | ||
Staurosporine induces programmed cell death in embryonic neurons and activation of the ceramide pathway. | Q36798604 | ||
Role of calpain- and interleukin-1 beta converting enzyme-like proteases in the beta-amyloid-induced death of rat hippocampal neurons in culture | Q36851898 | ||
BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases | Q37044625 | ||
Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury | Q37381665 | ||
Viral proteins E1B19K and p35 protect sympathetic neurons from cell death induced by NGF deprivation | Q38300412 | ||
Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase | Q40396045 | ||
Oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system | Q41002604 | ||
Persistent expression of Fas/FasL mRNA in the mouse hippocampus after a single NMDA injection. | Q41006591 | ||
Differential requirement for caspase 9 in apoptotic pathways in vivo. | Q41015558 | ||
Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak | Q41134694 | ||
Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract | Q41182414 | ||
An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat. | Q41191045 | ||
Involvement of NAD-poly(ADP-ribose) metabolism in p53 regulation and its consequences | Q41303518 | ||
Double identity for proteins of the Bcl-2 family | Q41508318 | ||
Expression of the baculovirus p35 gene inhibits mammalian neural cell death | Q41511453 | ||
Death substrates come alive | Q41516491 | ||
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. | Q41972615 | ||
Immunohistochemical analysis of in vivo patterns of expression of CPP32 (Caspase-3), a cell death protease. | Q42437005 | ||
Inhibition of human caspases by peptide-based and macromolecular inhibitors | Q42538024 | ||
Generation and identification of recombinant adenovirus by liposome-mediated transfection and PCR analysis. | Q44477631 | ||
Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: comparisons between immunocompetent and immunodeficient inbred strains. | Q45868863 | ||
Activation of CPP32 during apoptosis of neurons and astrocytes | Q46301226 | ||
The trophic action of IL-7 on pro-T cells: inhibition of apoptosis of pro-T1, -T2, and -T3 cells correlates with Bcl-2 and Bax levels and is independent of Fas and p53 pathways. | Q47937049 | ||
Delayed selective motor neuron death and fas antigen induction after spinal cord ischemia in rabbits | Q47963270 | ||
Cloning and expression of a rat brain interleukin-1beta-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons. | Q48053553 | ||
Evidence for involvement of Bax and p53, but not caspases, in radiation-induced cell death of cultured postnatal hippocampal neurons | Q48326868 | ||
A caspase inhibitor blocks ischaemia-induced delayed neuronal death in the gerbil | Q48389094 | ||
Role of caspases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons | Q48403884 | ||
Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia. | Q48455875 | ||
Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice. | Q48532390 | ||
Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase. | Q48589751 | ||
Neuroprotective effects of inhibiting poly(ADP-ribose) synthetase on focal cerebral ischemia in rats. | Q48589768 | ||
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. | Q48616927 | ||
Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury. | Q48628367 | ||
The role of CED-3-related cysteine proteases in apoptosis of cerebellar granule cells. | Q48637409 | ||
Attenuation of transient focal cerebral ischemic injury in transgenic mice expressing a mutant ICE inhibitory protein. | Q48738690 | ||
Ca2+ and reactive oxygen species in staurosporine-induced neuronal apoptosis. | Q48754812 | ||
Bax promotes neuronal cell death and is downregulated during the development of the nervous system. | Q48783689 | ||
p53 expression induces apoptosis in hippocampal pyramidal neuron cultures. | Q48799379 | ||
Effects of ICE-like protease and calpain inhibitors on neuronal apoptosis. | Q48827832 | ||
Evidence for p53-mediated modulation of neuronal viability. | Q48884313 | ||
Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species. | Q48957350 | ||
Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death. | Q49116308 | ||
Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis. | Q52532134 | ||
Increased expression of IL-1beta converting enzyme in hippocampus after ischemia: selective localization in microglia | Q57131501 | ||
Inhibition of ICE slows ALS in mice | Q59081638 | ||
Peptide inhibitors of the ICE protease family arrest programmed cell death of motoneurons in vivo and in vitro | Q71988397 | ||
Rapid allelotype analysis of p53 knockout mice | Q72402908 | ||
Nedd2 is required for apoptosis after trophic factor withdrawal, but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells | Q73101267 | ||
Inhibition of the interleukin-1 beta converting enzyme family rescues neurons from apoptotic death | Q73342941 | ||
Characterization of CPP32-like protease activity following apoptotic challenge in SH-SY5Y neuroblastoma cells | Q73373813 | ||
Caspase inhibition selectively reduces the apoptotic component of oxygen-glucose deprivation-induced cortical neuronal cell death | Q73561443 | ||
P53- and CD95-associated apoptosis in neurodegenerative diseases | Q74493496 | ||
Bax and Bak proteins require caspase activity to trigger apoptosis in sympathetic neurons | Q74562629 | ||
Proteases to die for | Q74630246 | ||
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell death | Q2383867 |
P304 | page(s) | 2996-3006 | |
P577 | publication date | 1999-04-01 | |
P1433 | published in | Journal of Neuroscience | Q1709864 |
P1476 | title | Contribution of p53-dependent caspase activation to neuronal cell death declines with neuronal maturation | |
P478 | volume | 19 |
Q36449204 | Acute neuroprotective synergy of erythropoietin and insulin-like growth factor I |
Q36325171 | Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death |
Q42820807 | Apoptotic actions of p53 require transcriptional activation of PUMA and do not involve a direct mitochondrial/cytoplasmic site of action in postnatal cortical neurons. |
Q44461861 | Ara-C induces apoptosis in monkey fibroblast cells. |
Q52165684 | Arsenite-induced apoptosis in cortical neurons is mediated by c-Jun N-terminal protein kinase 3 and p38 mitogen-activated protein kinase. |
Q57286198 | Atomic force microscopy reveals new biophysical markers for monitoring subcellular changes in oxidative injury: Neuroprotective effects of quercetin at the nanoscale |
Q48157353 | Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons |
Q58199992 | Caspase-independent death of meiotic and postmeiotic cells overexpressing p53: calpain involvement |
Q43662802 | Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage. |
Q37445826 | Cyclin-dependent kinases as a therapeutic target for stroke. |
Q34792871 | Cyclin-dependent kinases as potential targets to improve stroke outcome. |
Q42920112 | Death commitment point is advanced by axotomy in sympathetic neurons |
Q44356838 | Deltamethrin induces apoptotic cell death in cultured cerebral cortical neurons |
Q44216443 | Differential activation of caspase-3 at two maturational stages during okadaic acid-induced rat neuronal death |
Q34995125 | Do apoptotic mechanisms regulate synaptic plasticity and growth-cone motility? |
Q37323732 | Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons. |
Q34325335 | Four deaths and a funeral: from caspases to alternative mechanisms. |
Q33275853 | Full length Bid is sufficient to induce apoptosis of cultured rat hippocampal neurons |
Q33707780 | Hairless expression attenuates apoptosis in a mouse model and the COS cell line; involvement of p53. |
Q37169993 | Histone deacetylase inhibitors prevent p53-dependent and p53-independent Bax-mediated neuronal apoptosis through two distinct mechanisms |
Q74339183 | Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity |
Q36428738 | Hypothermic neuroprotection. |
Q43814130 | Inhibitors of trypsin-like serine proteases prevent DNA damage-induced neuronal death by acting upstream of the mitochondrial checkpoint and of p53 induction. |
Q36604805 | Interplay between the p53 tumor suppressor protein family and Cdk5: novel therapeutic approaches for the treatment of neurodegenerative diseases using selective Cdk inhibitors |
Q80551962 | Involvement of p53 and Fas/CD95 in murine neural progenitor cell response to ionizing irradiation |
Q43764358 | Kainate excitotoxicity in organotypic hippocampal slice cultures: evidence for multiple apoptotic pathways |
Q34439252 | MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death. |
Q34502221 | Mitochondrial and Cell Death Mechanisms in Neurodegenerative Diseases |
Q33951094 | Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease |
Q37180866 | Molecular regulation of DNA damage-induced apoptosis in neurons of cerebral cortex |
Q43848252 | Neural precursor cell apoptosis and glial tumorigenesis following transplacental ethyl-nitrosourea exposure |
Q34201997 | Neuronal life and death: an essential role for the p53 family |
Q48631093 | Prevention of apoptosis-inducing factor translocation is a possible mechanism for protective effects of hepatocyte growth factor against neuronal cell death in the hippocampus after transient forebrain ischemia. |
Q51263731 | Proapoptotic Requirement of Ribosomal Protein L11 in Ribosomal Stress-Challenged Cortical Neurons. |
Q46886447 | Puma is a dominant regulator of oxidative stress induced Bax activation and neuronal apoptosis. |
Q30978637 | Response of cell cycle proteins to neurotrophic factor and chemokine stimulation in human neuroglia |
Q33977411 | Role of AIF in caspase-dependent and caspase-independent cell death |
Q50335770 | The Brn-3a transcription factor inhibits the pro-apoptotic effect of p53 and enhances cell cycle arrest by differentially regulating the activity of the p53 target genes encoding Bax and p21(CIP1/Waf1). |
Q39806223 | The prolyl cis/trans isomerase cyclophilin 18 interacts with the tumor suppressor p53 and modifies its functions in cell cycle regulation and apoptosis. |
Q34201989 | The role of p53 in neuronal cell death |
Q36334008 | p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons |
Q35066712 | p53-dependent cell death signaling in neurons |
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