scholarly article | Q13442814 |
P50 | author | Jodi A Flaws | Q63198198 |
P2093 | author name string | E Li | |
A Greenberg | |||
G Macdonald | |||
J Yuan | |||
Y Sun | |||
H Hara | |||
L Bergeron | |||
L Shi | |||
M A Moskowitz | |||
J L Tilly | |||
G I Perez | |||
A Jurisicova | |||
K E Latham | |||
J C Salter | |||
S Varmuza | |||
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Transgenic-mouse model of amyotrophic lateral sclerosis | Q72442542 | ||
Nedd2 is required for apoptosis after trophic factor withdrawal, but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells | Q73101267 | ||
Substrate specificities of caspase family proteases | Q73201753 | ||
Immunolocalization of the ICE/Ced-3-family protease, CPP32 (Caspase-3), in non-Hodgkin's lymphomas, chronic lymphocytic leukemias, and reactive lymph nodes | Q73358709 | ||
Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis | Q73520806 | ||
Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions | Q24675072 | ||
Identification of a set of genes with developmentally down-regulated expression in the mouse brain | Q28187594 | ||
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme | Q28256420 | ||
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme | Q28287610 | ||
The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32 | Q28295448 | ||
RAIDD is a new 'death' adaptor molecule | Q28300622 | ||
Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock | Q28307404 | ||
Ablation of bcl-2 gene expression decreases the numbers of oocytes and primordial follicles established in the post-natal female mouse gonad | Q28504698 | ||
Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death | Q28507741 | ||
Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development | Q28590612 | ||
Activation of caspase-2 in apoptosis | Q28611454 | ||
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation | Q29547561 | ||
Caspases: killer proteases | Q29616315 | ||
Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity | Q34057782 | ||
The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death | Q34306496 | ||
Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme | Q34325458 | ||
Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice | Q34408475 | ||
Axotomy-induced neuronal death during development | Q35615481 | ||
Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage | Q36030783 | ||
Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor | Q36233580 | ||
Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases | Q36237706 | ||
Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury | Q36376859 | ||
The genes of cell death and cellular susceptibility to apoptosis in the ovary: a hypothesis | Q36390278 | ||
RIP and FADD: two "death domain"-containing proteins can induce apoptosis by convergent, but dissociable, pathways | Q37303348 | ||
Activation of an interleukin 1 converting enzyme-dependent apoptosis pathway by granzyme B. | Q37306593 | ||
Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions | Q37688651 | ||
ICE-like proteases in apoptosis | Q40443896 | ||
Protease activation during apoptosis: death by a thousand cuts? | Q40459802 | ||
Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis | Q41109952 | ||
The cell-death machine | Q41110699 | ||
Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B. | Q41284156 | ||
Inhibition of apoptosis by the expression of antisense Nedd2. | Q41326338 | ||
Death substrates come alive | Q41516491 | ||
Apoptosis and ovarian function | Q41670982 | ||
Characterization of apoptosis in cultured rat sympathetic neurons after nerve growth factor withdrawal | Q41817127 | ||
Interleukin-1 beta-converting enzyme-related proteases (IRPs) and mammalian cell death: dissociation of IRP-induced oligonucleosomal endonuclease activity from morphological apoptosis in granulosa cells of the ovarian follicle | Q42479450 | ||
Processing of the Nedd2 precursor by ICE-like proteases and granzyme B. | Q42811228 | ||
Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction. | Q48950370 | ||
Analysis of G protein alpha subunit mRNA abundance in preimplantation mouse embryos using a rapid, quantitative RT-PCR approach. | Q49047301 | ||
Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. | Q54515149 | ||
Inhibition of ICE slows ALS in mice | Q59081638 | ||
Differential Growth of the Mouse Preimplantation Embryo in Chemically Defined Media1 | Q62555335 | ||
P433 | issue | 9 | |
P921 | main subject | apoptotic process | Q14599311 |
P304 | page(s) | 1304-1314 | |
P577 | publication date | 1998-05-01 | |
P1433 | published in | Genes & Development | Q1524533 |
P1476 | title | Defects in regulation of apoptosis in caspase-2-deficient mice | |
P478 | volume | 12 |
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Q37146821 | A tumor suppressor function for caspase-2 |
Q35409026 | Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice |
Q31948409 | Activation of the caspase cascade during Stx1-induced apoptosis in Burkitt's lymphoma cells |
Q28576773 | Activity and expression of different members of the caspase family in the rat corpus luteum during pregnancy and postpartum |
Q55018023 | Acute Hepatopancreatic Necrosis Disease (AHPND) related microRNAs in Litopenaeus vannamei infected with AHPND-causing strain of Vibrio parahemolyticus. |
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Q34293102 | Apoptosis-regulating proteins as targets for drug discovery |
Q48437297 | Apoptosome dependent caspase-3 activation pathway is non-redundant and necessary for apoptosis in sympathetic neurons. |
Q34753431 | Apoptotic pathways: the roads to ruin |
Q41865581 | BH3-only protein BIM mediates heat shock-induced apoptosis |
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Q36322518 | Bcl-2-regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9 |
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Q30439566 | Caspase 2 activity contributes to the initial wave of germ cell apoptosis during the first round of spermatogenesis |
Q37627556 | Caspase 2 in apoptosis, the DNA damage response and tumour suppression: enigma no more? |
Q33705936 | Caspase 2-mediated tumor suppression involves survivin gene silencing |
Q36876621 | Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression |
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Q36643566 | Caspase function in programmed cell death |
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Q48908333 | Caspase mRNA expression in a rat model of focal cerebral ischemia. |
Q77508889 | Caspase-2 (Nedd-2) processing and death of trophic factor-deprived PC12 cells and sympathetic neurons occur independently of caspase-3 (CPP32)-like activity |
Q43594311 | Caspase-2 activation is redundant during seizure-induced neuronal death |
Q44028668 | Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis |
Q26863078 | Caspase-2 as a tumour suppressor |
Q40549968 | Caspase-2 can function upstream of bid cleavage in the TRAIL apoptosis pathway |
Q40753178 | Caspase-2 can trigger cytochrome C release and apoptosis from the nucleus. |
Q46467885 | Caspase-2 cleavage of tau reversibly impairs memory |
Q35688389 | Caspase-2 deficiency enhances aging-related traits in mice |
Q28587062 | Caspase-2 deficiency prevents programmed germ cell death resulting from cytokine insufficiency but not meiotic defects caused by loss of ataxia telangiectasia-mutated (Atm) gene function |
Q36084491 | Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability |
Q35349417 | Caspase-2 impacts lung tumorigenesis and chemotherapy response in vivo. |
Q28217828 | Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria |
Q50643031 | Caspase-2 involvement during ionizing radiation-induced oocyte death in the mouse ovary. |
Q37527207 | Caspase-2 is essential for c-Jun transcriptional activation and Bim induction in neuron death. |
Q24669697 | Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis |
Q57274132 | Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9 |
Q46809696 | Caspase-2 is required for cell death induced by cytoskeletal disruption |
Q35430964 | Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice. |
Q35137731 | Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts |
Q33497936 | Caspase-2 mediated apoptotic and necrotic murine macrophage cell death induced by rough Brucella abortus |
Q42023225 | Caspase-2 mediates a Brucella abortus RB51-induced hybrid cell death having features of apoptosis and pyroptosis |
Q73419649 | Caspase-2 mediates neuronal cell death induced by beta-amyloid |
Q34633549 | Caspase-2 pre-mRNA alternative splicing: Identification of an intronic element containing a decoy 3' acceptor site |
Q24337211 | Caspase-2 primes cancer cells for TRAIL-mediated apoptosis by processing procaspase-8 |
Q92534466 | Caspase-2 promotes AMPA receptor internalization and cognitive flexibility via mTORC2-AKT-GSK3β signaling |
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Q38216592 | Caspase-2: the reinvented enzyme |
Q36794903 | Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosis in vivo |
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Q40655812 | Caspase-mediated cleavage of the feline calicivirus capsid protein |
Q33857511 | Caspases - controlling intracellular signals by protease zymogen activation |
Q37593693 | Caspases and kinases in a death grip |
Q35187214 | Caspases and neuronal development |
Q44196938 | Caspases are not localized in mitochondria during life or death |
Q33598614 | Caspases as treatment targets in stroke and neurodegenerative diseases |
Q37302731 | Caspases in apoptosis and beyond |
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Q41526704 | Cell Death in the Developing Brain after Hypoxia-Ischemia |
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Q36768874 | Cell suicide and caspases |
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Q28293156 | Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reaction |
Q36796784 | Coenzyme Q10 rescues ethanol-induced corneal fibroblast apoptosis through the inhibition of caspase-2 activation. |
Q48666736 | Combined effect of hypothermia and caspase-2 gene deficiency on neonatal hypoxic-ischemic brain injury. |
Q34443613 | Commuting the death sentence: how oocytes strive to survive |
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Q33918620 | Correlation between apoptosis microarray gene expression profiling and histopathological lymph node lesions |
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Q35124238 | DRONC, an ecdysone-inducible Drosophila caspase |
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