| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0898-6568(01)00262-5 |
| P698 | PubMed publication ID | 11897488 |
| P50 | author | David J MacEwan | Q60310098 |
| P2860 | cites work | Continuous autotropic signaling by membrane-expressed tumor necrosis factor | Q77864007 |
| Tumour necrosis factor-alpha activates a calcium sensitization pathway in guinea-pig bronchial smooth muscle | Q77921077 | ||
| Tumor necrosis factor induces phosphorylation and translocation of BAD through a phosphatidylinositide-3-OH kinase-dependent pathway | Q77927060 | ||
| Soluble tumor necrosis factor receptors in sera from patients with insulin-dependent diabetes mellitus: relations to duration and complications of disease | Q78095372 | ||
| Roles of phosphatidylinositol 3-kinase and Rac in the nuclear signaling by tumor necrosis factor-alpha in rat-2 fibroblasts | Q78122439 | ||
| Differential effects of lipopolysaccharide and tumor necrosis factor on monocytic IkappaB kinase signalsome activation and IkappaB proteolysis | Q78151382 | ||
| Transmembrane tumor necrosis factor (TNF)-alpha inhibits adipocyte differentiation by selectively activating TNF receptor 1 | Q78208083 | ||
| Prevention of constitutive TNF receptor 1 signaling by silencer of death domains | Q22008692 | ||
| The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation | Q22009927 | ||
| RIP3, a novel apoptosis-inducing kinase | Q22009930 | ||
| Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis | Q22010649 | ||
| A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells | Q22253428 | ||
| Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule | Q24290576 | ||
| Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon | Q24294921 | ||
| Molecular cloning and expression of a receptor for human tumor necrosis factor | Q24303604 | ||
| FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis | Q24307362 | ||
| RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death | Q24307376 | ||
| RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase | Q24310179 | ||
| Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins | Q24311703 | ||
| BRE: a modulator of TNF-alpha action | Q24313397 | ||
| cPLA2 is phosphorylated and activated by MAP kinase | Q24314148 | ||
| MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase | Q24315104 | ||
| Inhibition of death receptor signals by cellular FLIP | Q24316446 | ||
| TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways | Q24317441 | ||
| A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor | Q24318280 | ||
| The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation | Q24318742 | ||
| NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176 | Q24319941 | ||
| A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase | Q24321384 | ||
| Identification of CARDIAK, a RIP-like kinase that associates with caspase-1 | Q24324244 | ||
| TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex | Q24329065 | ||
| Caspases: the executioners of apoptosis | Q24530218 | ||
| Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics | Q24564912 | ||
| PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid | Q24568285 | ||
| Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain | Q24604330 | ||
| The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation | Q24610637 | ||
| Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2 | Q24642851 | ||
| Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors | Q24672483 | ||
| The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN | Q24682087 | ||
| The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins | Q28117866 | ||
| Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance | Q28131660 | ||
| RIP2 is a Raf1-activated mitogen-activated protein kinase kinase | Q28137832 | ||
| Tumor necrosis factor receptor-associated factor (TRAF) family: adapter proteins that mediate cytokine signaling | Q28141969 | ||
| TNF-mediated activation of the stress-activated protein kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase related | Q28143924 | ||
| NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase | Q28144326 | ||
| Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD) | Q28145000 | ||
| The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways | Q28145665 | ||
| The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators | Q28198125 | ||
| The TNF and TNF receptor superfamilies: integrating mammalian biology | Q28203717 | ||
| New perspectives into the molecular pathogenesis and treatment of type 2 diabetes | Q28203726 | ||
| Identification of the phosphorylation sites of cytosolic phospholipase A2 in agonist-stimulated human platelets and HeLa cells | Q28262222 | ||
| Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis | Q28274211 | ||
| Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting [...] | Q28280257 | ||
| Ceramide inactivates cellular protein kinase Calpha | Q28281745 | ||
| FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex | Q28283294 | ||
| ASK1 is essential for JNK/SAPK activation by TRAF2 | Q28285612 | ||
| Identity of tumour necrosis factor and the macrophage-secreted factor cachectin | Q28286678 | ||
| Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme | Q28287610 | ||
| Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine | Q28287650 | ||
| Tumor necrosis factor-alpha-inducible IkappaBalpha proteolysis mediated by cytosolic m-calpain. A mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kappab activation | Q28292768 | ||
| A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP | Q28302244 | ||
| Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase | Q28302692 | ||
| MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1 | Q28302936 | ||
| Kinase suppressor of Ras is ceramide-activated protein kinase | Q28307245 | ||
| Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes | Q28506930 | ||
| Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection | Q28509078 | ||
| Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor | Q28512161 | ||
| Evidence for a role of MEK and MAPK during signal transduction by protein kinase C zeta | Q28582003 | ||
| Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes | Q28593744 | ||
| Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice | Q28593915 | ||
| TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40 | Q28610812 | ||
| The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor | Q28610826 | ||
| Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetes | Q33957444 | ||
| Life and death decisions: regulation of apoptosis by proteolysis of signaling molecules | Q33964319 | ||
| Activation of p38 mitogen-activated protein kinase by sodium salicylate leads to inhibition of tumor necrosis factor-induced IkappaB alpha phosphorylation and degradation | Q33995645 | ||
| MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis | Q33996873 | ||
| Noncaspase proteases in apoptosis | Q34037785 | ||
| Defying death after DNA damage. | Q34068957 | ||
| Tumour necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NF-kappaB. | Q34071248 | ||
| The tumour necrosis factor receptor family: life or death choices | Q34103388 | ||
| Control of apoptosis by IP(3) and ryanodine receptor driven calcium signals | Q34104059 | ||
| Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia | Q34165111 | ||
| Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha | Q34190131 | ||
| Tumour necrosis factor-alpha: the role of this multifunctional cytokine in asthma | Q34192914 | ||
| Enzymes of sphingolipid metabolism: from modular to integrative signaling | Q34220989 | ||
| Apoptotic and necrotic cell death induced by death domain receptors. | Q34226767 | ||
| Tumor necrosis factor (TNF). | Q34378376 | ||
| Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice | Q34408475 | ||
| A human suppressor of c-Jun N-terminal kinase 1 activation by tumor necrosis factor alpha | Q34441662 | ||
| BCL-2 family: regulators of cell death | Q34468840 | ||
| A high molecular weight component of the human tumor necrosis factor receptor is associated with cytotoxicity | Q34623575 | ||
| Distinct PKC isoforms mediate the activation of cPLA2 and adenylyl cyclase by phorbol ester in RAW264.7 macrophages | Q35028229 | ||
| Tumor necrosis factor alpha inhibits signaling from the insulin receptor | Q35304189 | ||
| The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor | Q35739690 | ||
| Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma | Q36231848 | ||
| Cytoplasmic phospholipase A2 activity and gene expression are stimulated by tumor necrosis factor: dexamethasone blocks the induced synthesis | Q36300832 | ||
| Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts | Q36351406 | ||
| A human tumor necrosis factor (TNF) alpha mutant that binds exclusively to the p55 TNF receptor produces toxicity in the baboon | Q36363020 | ||
| A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes | Q36364492 | ||
| A human tumor necrosis factor p75 receptor agonist stimulates in vitro T cell proliferation but does not produce inflammation or shock in the baboon | Q36367041 | ||
| Modulation of the nuclear factor kappa B pathway by Shp-2 tyrosine phosphatase in mediating the induction of interleukin (IL)-6 by IL-1 or tumor necrosis factor | Q36376086 | ||
| A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNF-R. | Q36401608 | ||
| Tumour necrosis factor (cachectin) induces phospholipase A2 activity and synthesis of a phospholipase A2-activating protein in endothelial cells | Q36433185 | ||
| Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation | Q36490362 | ||
| Involvement of caspase-dependent activation of cytosolic phospholipase A2 in tumor necrosis factor-induced apoptosis | Q36765200 | ||
| Evidence for exclusive role in signalling of tumour necrosis factor p55 receptor and a potentiating function of p75 receptor on human endothelial cells | Q41670881 | ||
| Cloning, expression and cross-linking analysis of the murine p55 tumor necrosis factor receptor | Q41678373 | ||
| Tumour-necrosis-factor-mediated cytotoxicity is correlated with phospholipase-A2 activity, but not with arachidonic acid release per se. | Q41699009 | ||
| Regulation of ceramide production and apoptosis | Q41748407 | ||
| Specific activation of beta-casein kinase by the inflammatory cytokines interleukin 1 and tumour necrosis factor | Q41774306 | ||
| Signal transduction of stress via ceramide | Q41841345 | ||
| Reduction in tumor necrosis factor receptor affinity and cytotoxicity by glucocorticoids | Q41898408 | ||
| Modulation of transmembrane signalling in HL-60 granulocytes by tumour necrosis factor-alpha | Q41968377 | ||
| Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. | Q41972615 | ||
| Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I | Q42015911 | ||
| Regulation of Raf-1 kinase by TNF via its second messenger ceramide and cross-talk with mitogenic signalling | Q42034188 | ||
| High affinity binding of 125I-labeled human tumor necrosis factor (LuKII) to specific cell surface receptors | Q42101211 | ||
| Sphingolipid metabolites differentially regulate extracellular signal-regulated kinase and stress-activated protein kinase cascades | Q42160174 | ||
| Potentiation by tumour necrosis factor-alpha of calcium signals induced by bradykinin and carbachol in human tracheal smooth muscle cells. | Q42369257 | ||
| Phosphorylation and activation of cytosolic phospholipase A2 by 38-kDa mitogen-activated protein kinase in collagen-stimulated human platelets | Q42439528 | ||
| Protein kinase Cmu downregulation of tumor-necrosis-factor-induced apoptosis correlates with enhanced expression of nuclear-factor-kappaB-dependent protective genes | Q42463364 | ||
| Priming of human neutrophil superoxide generation by tumour necrosis factor-alpha is signalled by enhanced phosphatidylinositol 3,4,5-trisphosphate but not inositol 1,4,5-trisphosphate accumulation. | Q42465157 | ||
| Tumor necrosis factor alpha decreases inositol phosphate formation and phosphatidylinositol-bisphosphate (PIP2) synthesis in rat cardiomyocytes | Q42500393 | ||
| Azotemia, TNF alpha, and LPS prime the human neutrophil oxidative burst by distinct mechanisms | Q42524400 | ||
| Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate | Q42556020 | ||
| Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins | Q42803708 | ||
| Cell killing and induction of manganous superoxide dismutase by tumor necrosis factor-alpha is mediated by lipoxygenase metabolites of arachidonic acid | Q42815385 | ||
| The p70 tumor necrosis factor receptor mediates cytotoxicity | Q42818138 | ||
| Role of the protein kinase C lambda/iota isoform in nuclear factor-kappaB activation by interleukin-1beta or tumor necrosis factor-alpha: cell type specificities | Q42819075 | ||
| Endothelin-stimulated Ca2+ mobilization by 3T3-L1 adipocytes is suppressed by tumor necrosis factor-alpha | Q42822843 | ||
| Tumor necrosis factor-alpha autoregulates interleukin-6 synthesis via activation of protein kinase C. Function of sphingosine 1-phosphate and phosphatidylcholine-specific phospholipase C. | Q42835431 | ||
| Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways | Q42972664 | ||
| Tumor necrosis factor-alpha activation of the c-Jun N-terminal kinase pathway in human neutrophils. Integrin involvement in a pathway leading from cytoplasmic tyrosine kinases apoptosis | Q43508921 | ||
| Modulated kinase activities in cells undergoing tumour necrosis factor-induced apoptotic cell death | Q43737355 | ||
| TNF-alpha receptors simultaneously activate Ca2+ mobilisation and stress kinases in cultured sensory neurones. | Q43828938 | ||
| Reduced tumour necrosis factor-induced cytotoxicity by inhibitors of the arachidonic acid metabolism | Q44303427 | ||
| Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism | Q44663979 | ||
| Specific macrophage receptor activity for advanced glycosylation end products inversely correlates with insulin levels in vivo | Q44830159 | ||
| The regulation of anoikis: MEKK-1 activation requires cleavage by caspases | Q46102806 | ||
| Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor | Q46254405 | ||
| Ceramide-dependent regulation of p42/p44 mitogen-activated protein kinase and c-Jun N-terminal-directed protein kinase in cultured airway smooth muscle cells | Q46884994 | ||
| Calcium signalling and the regulation of apoptosis | Q47792491 | ||
| Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factor | Q47992357 | ||
| Regulation of TNF-alpha-induced reorganization of the actin cytoskeleton and cell-cell junctions by Rho, Rac, and Cdc42 in human endothelial cells | Q48000569 | ||
| Respective role of TNF receptors in the development of experimental cerebral malaria. | Q48036126 | ||
| Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria | Q48037129 | ||
| Molecular cloning and expression of the mouse Tnf receptor type b | Q48242990 | ||
| Molecular Cloning and Expression of Human and Rat Tumor Necrosis Factor Receptor Chain (p60) and Its Soluble Derivative, Tumor Necrosis Factor-Binding Protein | Q48246983 | ||
| Differential role of calcium in tumour necrosis factor-mediated apoptosis and secretion of granulocyte-macrophage colony-stimulating factor in a T cell hybridoma. | Q49092822 | ||
| Two tumour necrosis factor receptors: structure and function. | Q49167492 | ||
| Dimerization of chimeric erythropoietin/75 kDa tumour necrosis factor (TNF) receptors transduces TNF signals: necessity for the 75 kDa-TNF receptor transmembrane domain. | Q49167499 | ||
| Generation and Biological Characterization of Membrane-bound, Uncleavable Murine Tumor Necrosis Factor | Q49167564 | ||
| Human tumor necrosis factor mutants with preferential binding to and activity on either the R55 or R75 receptor. | Q49168163 | ||
| Regulated commitment of TNF receptor signaling: a molecular switch for death or activation. | Q51083614 | ||
| Receptor binding and activation of polymorphonuclear neutrophils by tumor necrosis factor-alpha. | Q52489903 | ||
| Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice. | Q52542561 | ||
| Tumor necrosis factor receptor 2 plays a minor role for mycobacterial immunity. | Q54045877 | ||
| Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells. | Q54062670 | ||
| Differential activation of phospholipases during necrosis or apoptosis: A comparative study using tumor necrosis factor and anti-Fas antibodies | Q57203671 | ||
| Differential IκB Kinase Activation and IκBα Degradation by Interleukin-1β and Tumor Necrosis Factor-α in Human U937 Monocytic Cells | Q58450597 | ||
| p38 mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPLA2) in thrombin-stimulated platelets. Evidence that proline-directed phosphorylation is not required for mobilization of arachidonic acid by cPLA2 | Q28646211 | ||
| Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6 | Q28678886 | ||
| Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis | Q29547567 | ||
| Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function | Q29616104 | ||
| Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway | Q29616436 | ||
| The death domain kinase RIP mediates the TNF-induced NF-kappaB signal | Q29617727 | ||
| Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9 | Q29618617 | ||
| Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice | Q29618716 | ||
| IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance | Q29619774 | ||
| Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death | Q29620021 | ||
| Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C | Q29620247 | ||
| Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK | Q29620274 | ||
| Identification of Grb2 as a novel binding partner of tumor necrosis factor (TNF) receptor I. | Q30175435 | ||
| Protein kinase C-zeta phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin. | Q31527752 | ||
| Ceramide induces the dephosphorylation and inhibition of constitutively activated Akt in PTEN negative U87mg cells | Q31856628 | ||
| Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific | Q33336314 | ||
| The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation | Q33733316 | ||
| Complementary DNA cloning of a receptor for tumor necrosis factor and demonstration of a shed form of the receptor | Q33739657 | ||
| Signal transduction by tumour necrosis factor and tumour necrosis factor related ligands and their receptors | Q33782305 | ||
| Caspase knockouts: matters of life and death. | Q33782485 | ||
| Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein | Q33810622 | ||
| Serine/threonine protein kinases and apoptosis. | Q33876765 | ||
| A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling' | Q33890754 | ||
| LMP1 signal transduction differs substantially from TNF receptor 1 signaling in the molecular functions of TRADD and TRAF2 | Q33890869 | ||
| Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF. | Q33891000 | ||
| T cell life and death signalling via TNF-receptor family members | Q33898966 | ||
| Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor | Q33903826 | ||
| A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling | Q33907802 | ||
| TNF alpha and the TNF receptor superfamily: structure-function relationship(s). | Q33909217 | ||
| Selective down-regulation of IP(3)receptor subtypes by caspases and calpain during TNF alpha -induced apoptosis of human T-lymphoma cells | Q33919807 | ||
| Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned? | Q33937489 | ||
| Inverse, protean, and ligand-selective agonism: matters of receptor conformation | Q33938998 | ||
| BAD Enables Ceramide to Signal Apoptosis via Ras and Raf-1 | Q59123101 | ||
| In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis | Q59276547 | ||
| Interleukin-1β (IL-1β) and tumour necrosis factor (TNF) inhibit long-term potentiation in the rat dentate gyrus in vitro | Q62011163 | ||
| c-Jun is a downstream target for ceramide-activated protein phosphatase in A431 cells. | Q64967336 | ||
| Tumor Necrosis Factor-α Activates the Sphingomyelin Signal Transduction Pathway in a Cell-Free System | Q67487070 | ||
| TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown | Q67505708 | ||
| Involvement of Protein Kinase C in Regulating Tumor Necrosis Factor α-Stimulated Progesterone Production in Rat Preovulatory Folliclesin Vitro* | Q67913719 | ||
| Studies on the role of protein kinases in the TNF-mediated enhancement of murine tumor cell-endothelial cell interactions | Q68261262 | ||
| Characterization of the tumour necrosis factor receptor in human placenta | Q69839536 | ||
| Recombinant tumor necrosis factor and interleukin-1 both stimulate human synovial cell arachidonic acid release and phospholipid metabolism | Q70164749 | ||
| Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation | Q70607132 | ||
| Elevated cPLA2 levels as a mechanism by which the p70 TNF and p75 NGF receptors enhance apoptosis | Q70911661 | ||
| Effect of cell cycle on the regulation of the cell surface and secreted forms of type I and type II human tumor necrosis factor receptors | Q70915391 | ||
| Activation of the TNF alpha-p55 receptor induces myocyte proliferation and modulates agonist-evoked calcium transients in cultured human tracheal smooth muscle cells | Q71184938 | ||
| Tumour necrosis factor receptor II (p75) signalling is required for the migration of Langerhans' cells | Q71216216 | ||
| Tumor necrosis factor receptors (Tnfr) in mouse fibroblasts deficient in Tnfr1 or Tnfr2 are signaling competent and activate the mitogen-activated protein kinase pathway with differential kinetics | Q71763127 | ||
| Tumor necrosis factor-alpha increases airway responsiveness and sputum neutrophilia in normal human subjects | Q71842573 | ||
| Ceramide-induced translocation of protein kinase C-delta and -epsilon to the cytosol. Implications in apoptosis | Q71985250 | ||
| Cell density-dependent regulation of cell surface expression of two types of human tumor necrosis factor receptors and its effect on cellular response | Q72021714 | ||
| TNF-alpha stimulates increased plasma membrane guanine nucleotide binding protein activity in polymorphonuclear leukocytes | Q72615990 | ||
| Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling | Q72710788 | ||
| TNF-alpha stimulation of MCP-1 expression is mediated by the Akt/PKB signal transduction pathway in vascular endothelial cells | Q73067217 | ||
| Tumor necrosis factor-alpha mediates antiapoptotic signals partially via p38 MAP kinase activation in human eosinophils | Q73102185 | ||
| Serine phosphorylation of p60 tumor necrosis factor receptor by PKC-delta in TNF-alpha-activated neutrophils | Q73190968 | ||
| The p80 TNF receptor-associated kinase (p80TRAK) associates with residues 354-397 of the p80 cytoplasmic domain: similarity to casein kinase | Q73240965 | ||
| Phosphorylation of the membrane proximal region of tumor necrosis factor receptor CD120a (p55) at ERK consensus sites | Q73509813 | ||
| Inhibition of protein tyrosine phosphatases causes phosphorylation of tyrosine-331 in the p60 TNF receptor and inactivates the receptor-associated kinase | Q73545444 | ||
| Specific detection of an interleukin 1- and tumour necrosis factor-activated beta-casein kinase in HeLa and KB cells | Q73545713 | ||
| Pervanadate-induced nuclear factor-kappaB activation requires tyrosine phosphorylation and degradation of IkappaBalpha. Comparison with tumor necrosis factor-alpha | Q73561082 | ||
| Tumor necrosis factor employs a protein-tyrosine phosphatase to inhibit activation of KDR and vascular endothelial cell growth factor-induced endothelial cell proliferation | Q73643288 | ||
| Stimulation of stress-activated but not mitogen-activated protein kinases by tumour necrosis factor receptor subtypes in airway smooth muscle | Q73667162 | ||
| Tumor necrosis factor-alpha augments contraction and cytosolic Ca(2+) sensitivity through phospholipase A(2) in bovine tracheal smooth muscle | Q73670721 | ||
| Cyclic nucleotides suppress tumor necrosis factor alpha-mediated apoptosis by inhibiting caspase activation and cytochrome c release in primary hepatocytes via a mechanism independent of Akt activation | Q73704166 | ||
| The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation | Q73745042 | ||
| Selective down-regulation of the G(q)alpha/G11alpha G-protein family in tumour necrosis factor-alpha induced cell death | Q73853376 | ||
| Activation of p55 tumor necrosis factor-alpha receptor-1 coupled to tumor necrosis factor receptor-associated factor 2 stimulates intercellular adhesion molecule-1 expression by modulating a thapsigargin-sensitive pathway in human tracheal smooth mu | Q73910572 | ||
| TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival | Q73925277 | ||
| Effect of TNF-alpha on SMIT mRNA levels and myo-inositol accumulation in cultured endothelial cells | Q74153381 | ||
| Tumor necrosis factor (TNF) receptor type 2 mediates thymocyte proliferation independently of TNF receptor type 1 | Q74251703 | ||
| Fas-induced arachidonic acid release is mediated by Ca2+-independent phospholipase A2 but not cytosolic phospholipase A2, which undergoes proteolytic inactivation | Q74567469 | ||
| Both TNF receptors are required for direct TNF-mediated cytotoxicity in microvascular endothelial cells | Q77646970 | ||
| Changes of phospholipase D activity in TNF-alpha and anti-Fas/Apo1 monoclonal antibody induced apoptosis in HL-60 and A20 cells | Q77750005 | ||
| Diversity and complexity of ceramide signalling in apoptosis | Q77780124 | ||
| Cleavage of the calpain inhibitor, calpastatin, during apoptosis | Q77812601 | ||
| Tumor necrosis factor induces rapid production of 1'2'diacylglycerol by a phosphatidylcholine-specific phospholipase C. | Q41659611 | ||
| Slow increase in intranuclear and cytosolic free calcium concentrations in L929 cells is important in tumour necrosis factor-alpha-mediated cell death | Q36839918 | ||
| Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors | Q36852093 | ||
| RIP and FADD: two "death domain"-containing proteins can induce apoptosis by convergent, but dissociable, pathways | Q37303348 | ||
| Cellular receptor for 125I-labeled tumor necrosis factor: specific binding, affinity labeling, and relationship to sensitivity | Q37530212 | ||
| Tumor necrosis factor: specific binding and internalization in sensitive and resistant cells | Q37554963 | ||
| The two different receptors for tumor necrosis factor mediate distinct cellular responses | Q37609601 | ||
| Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha | Q37617716 | ||
| Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells. | Q37626367 | ||
| Dissociation of TNF-alpha cytotoxic and proinflammatory activities by p55 receptor- and p75 receptor-selective TNF-alpha mutants. | Q37628836 | ||
| Tumor necrosis factor (TNF)-alpha activates c-raf-1 kinase via the p55 TNF receptor engaging neutral sphingomyelinase. | Q37695056 | ||
| Tumour necrosis factor signal transduction | Q37902346 | ||
| Protein-tyrosine phosphatase inhibitors block tumor necrosis factor-dependent activation of the nuclear transcription factor NF-kappa B. | Q38295587 | ||
| Functions of sphingolipids and sphingolipid breakdown products in cellular regulation | Q38597926 | ||
| Activation of p38 mitogen-activated protein kinase in vivo selectively induces apoptosis of CD8(+) but not CD4(+) T cells | Q39450773 | ||
| Tumor necrosis factor receptor-mediated signaling pathways | Q40669397 | ||
| Structure-activity studies of human tumour necrosis factors | Q40731107 | ||
| Tumor necrosis factor-alpha inhibits store-mediated Ca2+ entry in the human hepatocellular carcinoma cell line HepG2. | Q40806599 | ||
| Transcriptional regulation of rat Na(+)/H(+) exchanger isoform-2 (NHE-2) gene by Sp1 transcription factor | Q40814983 | ||
| Phosphorylation of the tumor necrosis factor receptor CD120a (p55) recruits Bcl-2 and protects against apoptosis | Q40816786 | ||
| Unmodified calcium concentrations in tumour necrosis factor receptor subtype-mediated apoptotic cell death | Q40845575 | ||
| Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor | Q40853190 | ||
| Functional dichotomy of protein kinase C (PKC) in tumor necrosis factor-alpha (TNF-alpha ) signal transduction in L929 cells. Translocation and inactivation of PKC by TNF-alpha. | Q40869425 | ||
| PI3-K/AKT regulation of NF-kappaB signaling events in suppression of TNF-induced apoptosis | Q40881979 | ||
| Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473. | Q40883173 | ||
| Characterisation of receptor-specific TNFalpha functions in adipocyte cell lines lacking type 1 and 2 TNF receptors | Q40894968 | ||
| TGF-beta-induced matrix proteins inhibit p42/44 MAPK and JNK activation and suppress TNF-mediated IkappaBalpha degradation and NF-kappaB nuclear translocation in L929 fibroblasts | Q40908266 | ||
| Through thick and thin: wasting, obesity, and TNF alpha | Q40910406 | ||
| Phosphorylation of tumor necrosis factor receptor CD120a (p55) by p42(mapk/erk2) induces changes in its subcellular localization | Q40919242 | ||
| Engagement of tumor necrosis factor (TNF) receptor 1 leads to ATF-2- and p38 mitogen-activated protein kinase-dependent TNF-alpha gene expression | Q40923038 | ||
| Involvement of protein kinase C-beta and ceramide in tumor necrosis factor-alpha-induced but not Fas-induced apoptosis of human myeloid leukemia cells | Q40937114 | ||
| Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation. Evidence for an interleukin-13-driven phosphatidylinositol 3-kinase-dependent survival mechanism | Q40950606 | ||
| Activation of the p38 mitogen-activated protein kinase pathway by Epstein-Barr virus-encoded latent membrane protein 1 coregulates interleukin-6 and interleukin-8 production | Q40951743 | ||
| Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase | Q40954925 | ||
| JNK and p53 stress signaling cascades are altered in MCF-7 cells resistant to tumor necrosis factor-mediated apoptosis | Q40959065 | ||
| Tumor necrosis factor-alpha mediates both apoptotic cell death and cell proliferation in a human hematopoietic cell line dependent on mitotic activity and receptor subtype expression | Q40964931 | ||
| Non-specific effects of methyl ketone peptide inhibitors of caspases | Q40977161 | ||
| Activation of p42/p44 mitogen-activated protein kinases (MAPK) and p38 MAPK by tumor necrosis factor (TNF) is mediated through the death domain of the 55-kDa TNF receptor | Q40981890 | ||
| Cleavage of human cytosolic phospholipase A2 by caspase-1 (ICE) and caspase-8 (FLICE). | Q40984121 | ||
| TNF inhibits insulin induced STAT5 activation in differentiated mouse muscle cells pmi28. | Q40986635 | ||
| Interleukin-4 down-regulates both forms of tumor necrosis factor receptor and receptor-mediated apoptosis, NF-kappaB, AP-1, and c-Jun N-terminal kinase. Comparison with interleukin-13. | Q40990917 | ||
| TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways | Q40992331 | ||
| Differential requirement for caspase 9 in apoptotic pathways in vivo. | Q41015558 | ||
| High levels of circulating soluble receptors for tumor necrosis factor in hairy cell leukemia and type B chronic lymphocytic leukemia | Q41020010 | ||
| Protein tyrosine kinase inhibitors block tumor necrosis factor-induced activation of nuclear factor-kappaB, degradation of IkappaBalpha, nuclear translocation of p65, and subsequent gene expression | Q41045910 | ||
| Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals | Q41050794 | ||
| Tumor necrosis factor receptor (TNFR)-associated factor 2A (TRAF2A), a TRAF2 splice variant with an extended RING finger domain that inhibits TNFR2-mediated NF-kappaB activation | Q41056335 | ||
| p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor. | Q41062073 | ||
| Ras signaling in tumor necrosis factor-induced apoptosis. | Q41076852 | ||
| Induction of endothelial cell surface adhesion molecules by tumor necrosis factor is blocked by protein tyrosine phosphatase inhibitors: role of the nuclear transcription factor NF-kappa B. | Q41085611 | ||
| Tumor necrosis factor alpha inhibits collagen alpha 1(I) gene expression in rat hepatic stellate cells through a G protein | Q41097795 | ||
| Phospholipase A2 is necessary for tumor necrosis factor alpha-induced ceramide generation in L929 cells | Q41100173 | ||
| Membrane tumor necrosis factor (TNF) induced cooperative signaling of TNFR60 and TNFR80 favors induction of cell death rather than virus production in HIV-infected T cells | Q41135083 | ||
| Function of the p55 tumor necrosis factor receptor "death domain" mediated by phosphatidylcholine-specific phospholipase C. | Q41180999 | ||
| The role of the two TNF receptors in proliferation, NF-kappa B activation and discrimination between TNF and LT alpha signalling in the human myeloma cell line OH-2. | Q41193709 | ||
| Distinct roles of the two tumor necrosis factor (TNF) receptors in modulating TNF and lymphotoxin alpha effects | Q41204959 | ||
| Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. | Q41218044 | ||
| Phosphorylation of Raf by ceramide-activated protein kinase | Q41270560 | ||
| Casein kinase-1 phosphorylates the p75 tumor necrosis factor receptor and negatively regulates tumor necrosis factor signaling for apoptosis | Q41284110 | ||
| Cytotoxicity in L929 murine fibrosarcoma cells after triggering of transfected human p75 tumour necrosis factor (TNF) receptor is mediated by endogenous murine TNF | Q41331780 | ||
| Involvement of the tumor necrosis factor receptor p75 in mediating cytotoxicity and gene regulating activities | Q41431059 | ||
| Both type I and type II interferons down-regulate human tumor necrosis factor receptors in human hepatocellular carcinoma cell line Hep G2. Role of protein kinase C. | Q41495297 | ||
| A novel domain within the 55 kd TNF receptor signals cell death | Q41528172 | ||
| Human TNF mutants with selective activity on the p55 receptor. | Q41578169 | ||
| Tumor necrosis factor‐mediated cell lysis in vitro: relationship to cAMP accumulation and guanine nucleotide‐binding proteins | Q41633637 | ||
| Characterization of a recombinant extracellular domain of the type 1 tumor necrosis factor receptor: evidence for tumor necrosis factor .alpha. induced receptor aggregation | Q41640396 | ||
| Stress-activated protein kinases: activation, regulation and function. | Q41647879 | ||
| P433 | issue | 6 | |
| P921 | main subject | TNF | Q18032037 |
| P1104 | number of pages | 16 | |
| P304 | page(s) | 477-492 | |
| P577 | publication date | 2002-06-01 | |
| P1433 | published in | Cellular Signalling | Q1524097 |
| P1476 | title | TNF receptor subtype signalling: differences and cellular consequences | |
| P478 | volume | 14 |
| Q33923409 | A crucial role for tumor necrosis factor receptor 1 in synovial lining cells and the reticuloendothelial system in mediating experimental arthritis |
| Q35823352 | A novel tumour necrosis factor receptor mutation in a Finnish family with periodic fever syndrome |
| Q34851612 | A pro-inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor-associated periodic syndrome (TRAPS) |
| Q37910320 | A role for tumor necrosis factor-α in ischemia and ischemic preconditioning |
| Q42039878 | Activation and crosstalk between TNF family receptors in umbilical cord blood cells is not responsible for loss of engraftment capacity following culture |
| Q44532379 | Acute application of TNF stimulates apical 70-pS K+ channels in the thick ascending limb of rat kidney |
| Q35868063 | Adult neuron survival strategies--slamming on the brakes |
| Q50441175 | Age- and gender-dependent changes in circulating concentrations of tumor necrosis factor-α, soluble tumor necrosis factor receptor-1 and sulfated glycosaminoglycan in healthy people. |
| Q36926352 | Age-related changes to tumor necrosis factor receptors affect neuron survival in the presence of beta-amyloid |
| Q53821941 | Ameliorative Effect of Beraprost Sodium on Celecoxib Induced Cardiotoxicity in Rats. |
| Q42257703 | An important role of tumor necrosis factor receptor-2 on natural killer T cells on the development of dsRNA-enhanced Th2 cell response to inhaled allergens |
| Q40101284 | Anti-tumor action of tumor necrosis factor against Bomirski Ab melanoma in hamsters |
| Q36998861 | Anticytokine therapy in neuropathic pain management |
| Q33791816 | Antidepressive effect of mirtazapine in post-myocardial infarction depression is associated with soluble TNF-R1 increase: data from the MIND-IT. |
| Q39084991 | Antioxidant and anti-inflammatory effects of zinc. Zinc-dependent NF-κB signaling. |
| Q24305579 | Antisense abrogation of DENN expression induces apoptosis of leukemia cells in vitro, causes tumor regression in vivo and alters the transcription of genes involved in apoptosis and the cell cycle |
| Q27026686 | Apolipoprotein A-I: insights from redox proteomics for its role in neurodegeneration |
| Q44352698 | Arecoline-induced death of human leukemia K562 cells is associated with surface up-modulation of TNFR2. |
| Q36998952 | Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease |
| Q44320636 | Bradykinin induces interleukin-6 production in human airway smooth muscle cells: modulation by Th2 cytokines and dexamethasone. |
| Q24336952 | CARP-2 is an endosome-associated ubiquitin ligase for RIP and regulates TNF-induced NF-kappaB activation |
| Q37299649 | CCAAT/enhancer binding proteins alpha and beta regulate the tumor necrosis factor receptor 1 gene promoter |
| Q24529062 | CDX1 is an important molecular mediator of Barrett's metaplasia |
| Q35782408 | Cause-effect relations between 55 kD soluble TNF receptor concentrations and specific and unspecific symptoms in a patient with mild SLE disease activity: an exploratory time series analysis study |
| Q28570310 | Cell-specific expression and lipopolysaccharide-induced regulation of tumor necrosis factor alpha (TNFalpha) and TNF receptors in rat dorsal root ganglion |
| Q40106761 | Ceramide mediates inhibition of the renal epithelial sodium channel by tumor necrosis factor-alpha through protein kinase C. |
| Q36320314 | Ceramide sphingolipid signaling mediates Tumor Necrosis Factor (TNF)-dependent toxicity via caspase signaling in dopaminergic neurons |
| Q42241985 | Characterization of TNF receptor subtype expression and signaling on pulmonary endothelial cells in mice |
| Q35980026 | Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1β or TNF-α Release from Human Hepatic Stellate Cells |
| Q42869917 | Circulating TNF alpha receptor levels identify older adults who fail to regain weight after acute weight loss |
| Q35804154 | Circulating TNF receptors 1 and 2 predict stage 3 CKD in type 1 diabetes |
| Q84349469 | Colitogenic role of tumour necrosis factor (TNF) receptors in trinitrobenzene sulphonic acid colitis: TNF-R1 ablation does not affect systemic inflammatory response |
| Q39387318 | Connexin Channels at the Glio-Vascular Interface: Gatekeepers of the Brain |
| Q48201600 | Constitutive expression of p55TNFR mRNA and mitogen-specific up-regulation of TNF alpha and p75TNFR mRNA in mouse brain |
| Q30358256 | Constitutive smooth muscle tumour necrosis factor regulates microvascular myogenic responsiveness and systemic blood pressure |
| Q35181668 | Contact-dependent signaling during the late events of platelet activation. |
| Q39509256 | Contribution of Pro-inflammatory Cytokine Signaling within Midbrain Periaqueductal Gray to Pain Sensitivity in Parkinson's Disease via GABAergic Pathway |
| Q41890618 | Convergent actions of I kappa B kinase beta and protein kinase C delta modulate mRNA stability through phosphorylation of 14-3-3 beta complexed with tristetraprolin |
| Q38857733 | Curcumin induces apoptosis and suppresses invasion through MAPK and MMP signaling in human monocytic leukemia SHI-1 cells |
| Q37987351 | Current understanding of rheumatoid arthritis therapy |
| Q37351994 | Cytokine and chemokine regulation of sensory neuron function. |
| Q44709528 | Cytokine upregulation of surface antigens correlates to the priming of the neutrophil oxidative burst response |
| Q53257548 | Death-associated protein kinase controls STAT3 activity in intestinal epithelial cells. |
| Q64105541 | Deletion of tumour necrosis factor α receptor 1 elicits an increased TH17 immune response in the chronically inflamed liver |
| Q81601968 | Demonstration of specific antibodies against infliximab induced during treatment of a patient with ankylosing spondylitis |
| Q91876510 | Development and Characterization of a Potent Tumor Necrosis Factor-Alpha-Blocking Agent |
| Q36022796 | Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects |
| Q37428563 | Different expression levels of TNF receptors on the rheumatoid synovial macrophages derived from surgery and a synovectomy as detected by a new flow cytometric analysis |
| Q46500041 | Differential role of tumor necrosis factor receptors in TNBS colitis |
| Q34974357 | Effect of tumor necrosis factor-α on neutralization of ventricular fibrillation in rats with acute myocardial infarction. |
| Q34031992 | Effect of tumor necrosis factor-α on ventricular arrhythmias in rats with acute myocardial infarction in vivo |
| Q92825186 | Effects of cytokines on nuclear factor-kappa B, cell viability, and synaptic connectivity in a human neuronal cell line |
| Q46733359 | Effects of elastase and cathepsin G on the levels of membrane and soluble TNFalpha |
| Q28574613 | Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNFalpha-induced MEK/ERK signalling |
| Q24682686 | Elevated NF-kappaB responses and FLIP levels in leukemic but not normal lymphocytes: reduction by salicylate allows TNF-induced apoptosis |
| Q55519459 | Elucidation of stannin function using microarray analysis: implications for cell cycle control. |
| Q39988374 | Enhanced susceptibility to Con A-induced liver injury in mice transgenic for the intracellular isoform of human TNF receptor type 2. |
| Q40545014 | Epidermal growth factor receptor transactivation mediates tumor necrosis factor-induced hepatocyte replication |
| Q40537800 | Erythropoietin-dependent autocrine secretion of tumor necrosis factor-alpha in hematopoietic cells modulates proliferation via MAP kinase--ERK-1/2 and does not require tyrosine docking sites in the EPO receptor. |
| Q33523291 | Expression and function of TNF and IL-1 receptors on human regulatory T cells |
| Q39542019 | Expression and purification of a natural N-terminal pre-ligand assembly domain of tumor necrosis factor receptor 1 (TNFR1 PLAD) and preliminary activity determination |
| Q44683813 | Expression of both TNF-alpha receptor subtypes is essential for optimal skin tumour development |
| Q45417566 | Expression of tumor necrosis factor-alpha in IgM+ B-cells from bovine leukemia virus-infected lymphocytotic sheep |
| Q46836350 | Extracellular inosine participates in tumor necrosis factor-alpha induced nitric oxide production in cultured Sertoli cells |
| Q38995223 | Galloyl benzamide-based compounds modulating tumour necrosis factor α-stimulated c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signalling pathways |
| Q30837420 | Ganoderma lucidum polysaccharides in human monocytic leukemia cells: from gene expression to network construction |
| Q40508783 | Granulocyte macrophage-colony stimulating factor and interleukin-3 increase expression of type II tumour necrosis factor receptor, increasing susceptibility to tumour necrosis factor-induced apoptosis. Control of leukaemia cell life/death switching |
| Q24306786 | HO-1 underlies resistance of AML cells to TNF-induced apoptosis |
| Q40705143 | High molecular weight hyaluronic acid regulates MMP13 expression in chondrocytes via DUSP10/MKP5. |
| Q35423449 | High throughput short interfering RNA (siRNA) screening of the human kinome identifies novel kinases controlling the canonical nuclear factor-κB (NF-κB) activation pathway |
| Q34280666 | Human tumour necrosis factor: physiological and pathological roles in placenta and endometrium |
| Q37148694 | IAPs: what's in a name? |
| Q39881543 | IL-1beta augments TNF-alpha-mediated inflammatory responses from lung epithelial cells |
| Q38334917 | Identification of a novel tumor necrosis factor alpha-responsive region in the NCF2 promoter |
| Q34996118 | Immune and cell therapy of hematologic malignancies |
| Q37521988 | Immune cell-mediated liver injury |
| Q36447409 | Immune-neural connections: how the immune system's response to infectious agents influences behavior |
| Q36368359 | Immune-neuroendocrine integration at the adrenal gland: cytokine control of the adrenomedullary transcriptome |
| Q36623309 | Immunopathogenesis of Staphylococcus aureus pulmonary infection. |
| Q90248470 | Immunotherapies in Huntington's disease and α-Synucleinopathies |
| Q35986305 | Impact of aging on pulmonary responses to acute ozone exposure in mice: role of TNFR1. |
| Q37581328 | Impact of long-term high-intensity interval and moderate-intensity continuous training on subclinical inflammation in overweight/obese adults |
| Q51466555 | Impaired inflammatory angiogenesis, but not leukocyte influx, in mice lacking TNFR1. |
| Q33716115 | Inactivation of membrane tumor necrosis factor alpha by gingipains from Porphyromonas gingivalis |
| Q79246476 | Increased expression of CD95-ligand and other apoptotic signaling factors by fumonisin B1, a hepatotoxic mycotoxin, in livers of mice lacking tumor necrosis factor α |
| Q34315928 | Inflammation imaging of atherosclerosis in Apo-E-deficient mice using a (99m)Tc-labeled dual-domain cytokine ligand |
| Q35025400 | Inflammation, kidney function and albuminuria in the Framingham Offspring cohort |
| Q28485217 | Inflammatory cascades driven by tumor necrosis factor-alpha play a major role in the progression of acute liver failure and its neurological complications |
| Q39021598 | Inhibition of endocytosis exacerbates TNF-α-induced endothelial dysfunction via enhanced JNK and p38 activation |
| Q42832279 | Inhibition of p38 mitogen-activated protein kinase reduces TNF-induced activation of NF-kappaB, elicits caspase activity, and enhances cytotoxicity |
| Q45298602 | Inhibition of soluble tumor necrosis factor is therapeutic in Huntington's disease |
| Q54705304 | Inhibition of tumor necrosis factor receptor-1-mediated pathways has beneficial effects in a murine model of postischemic remodeling. |
| Q35672041 | Innate and ozone-induced airway hyperresponsiveness in obese mice: role of TNF-α. |
| Q48216518 | Integrated Immunomodulatory Mechanisms through which Long-Chain n-3 Polyunsaturated Fatty Acids Attenuate Obese Adipose Tissue Dysfunction |
| Q52647764 | Integrated Lung and Tracheal mRNA-Seq and miRNA-Seq Analysis of Dogs with an Avian-Like H5N1 Canine Influenza Virus Infection. |
| Q36994278 | Interactions between TNF and GnRH. |
| Q84118976 | Lack of TNFR2 expression by CD4(+) T cells exacerbates experimental colitis |
| Q42002775 | Lactic acid bacteria strains exert immunostimulatory effect on H. pylori-induced dendritic cells |
| Q35054688 | Lentiviral vector-mediated stable expression of sTNFR-Fc in human macrophage and neuronal cells as a potential therapy for neuroAIDS. |
| Q50907796 | Levels of TNF-α, soluble TNF receptors (sTNFR1, sTNFR2), and cognition in bipolar disorder. |
| Q40368922 | Low TNF-induced NF-kappaB and p38 phosphorylation levels in leucocytes in tumour necrosis factor receptor-associated periodic syndrome |
| Q46615280 | Low over-expression of TNFalpha in the mouse heart increases contractile performance via TNFR1. |
| Q35546498 | Mechanisms of inflammation-mediated airway smooth muscle plasticity and airways remodeling in asthma |
| Q26742077 | Microglia Ontology and Signaling |
| Q37416067 | Mode of action of cytokines on nociceptive neurons |
| Q42133212 | Modulation of Voltage-Gated Sodium Channels by Activation of Tumor Necrosis Factor Receptor-1 and Receptor-2 in Small DRG Neurons of Rats |
| Q53635320 | Modulation of autocrine TNF-alpha-stimulated matrix metalloproteinase 9 (MMP-9) expression by mitogen-activated protein kinases in THP-1 monocytic cells. |
| Q38955023 | Morinda citrifolia (Noni) Fruit Juice Reduces Inflammatory Cytokines Expression and Contributes to the Maintenance of Intestinal Mucosal Integrity in DSS Experimental Colitis. |
| Q40525423 | Mutant forms of tumour necrosis factor receptor I that occur in TNF-receptor-associated periodic syndrome retain signalling functions but show abnormal behaviour. |
| Q64099905 | NFkappaB is a Key Player in the Crosstalk between Inflammation and Cardiovascular Diseases |
| Q64892288 | Network pharmacology-based identification of potential targets of the flower of Trollius chinensis Bunge acting on anti-inflammatory effectss. |
| Q64106095 | Neuroinflammation and central PI3K/Akt/mTOR signal pathway contribute to bone cancer pain |
| Q36919403 | Neuroinflammatory mechanisms in Parkinson's disease: potential environmental triggers, pathways, and targets for early therapeutic intervention |
| Q37760062 | Neurological adverse events associated with anti-tumor necrosis factor α treatment |
| Q80814295 | Neutral sphingomyelinase inhibition participates to the benefits of N-acetylcysteine treatment in post-myocardial infarction failing heart rats |
| Q30009577 | Neutrophil cell surface receptors and their intracellular signal transduction pathways. |
| Q37801950 | New developments on the TNFα-mediated signalling pathways |
| Q36230078 | Obesity and airway responsiveness: role of TNFR2 |
| Q34534877 | Opposite role of tumor necrosis factor receptors in dextran sulfate sodium-induced colitis in mice |
| Q47753241 | PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer's diseases |
| Q44189430 | Paradoxical role of tumor necrosis factor alpha in fumonisin-induced hepatotoxicity in mice |
| Q89098798 | Participation of pro-inflammatory cytokines in neuropathic pain evoked by chemotherapeutic oxaliplatin via central GABAergic pathway |
| Q64116952 | Pathological mechanisms and therapeutic outlooks for arthrofibrosis |
| Q48292563 | Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice |
| Q33607485 | Peripheral cytokines as a chemical mediator for postconcussion like sickness behaviour in trauma and perioperative patients: literature review. |
| Q54692895 | Peritoneal mesothelial cells produce inflammatory related cytokines. |
| Q46634751 | Phospholipase D1 plays a key role in TNF-alpha signaling |
| Q57072486 | Photocrosslinkable Gelatin Hydrogels Modulate the Production of the Major Pro-inflammatory Cytokine, TNF-α, by Human Mononuclear Cells |
| Q58721338 | Preliminary study showing no association between G238A (rs361525) tumor necrosis factor-α (TNF-α) gene polymorphism and its serum level, hormonal and biochemical aspects of polycystic ovary syndrome |
| Q57651476 | Profound lymphopenia and bacteraemia |
| Q38103622 | Progesterone protective effects in neurodegeneration and neuroinflammation |
| Q55121508 | Proinflammatory Factors Mediate Paclitaxel-Induced Impairment of Learning and Memory. |
| Q46713278 | Proinflammatory cytokines inhibit human placental 11beta-hydroxysteroid dehydrogenase type 2 activity through Ca2+ and cAMP pathways. |
| Q24806392 | Prostaglandin F2alpha- and FAS-activating antibody-induced regression of the corpus luteum involves caspase-8 and is defective in caspase-3 deficient mice |
| Q40273360 | Prostaglandin J2 alters pro-survival and pro-death gene expression patterns and 26 S proteasome assembly in human neuroblastoma cells |
| Q38631578 | Protective role of cellular prion protein against TNFα-mediated inflammation through TACE α-secretase |
| Q47905774 | Protective role of tumor necrosis factor (TNF) receptors in chronic intestinal inflammation: TNFR1 ablation boosts systemic inflammatory response |
| Q33786961 | Protein kinase Cepsilon inhibits UVR-induced expression of FADD, an adaptor protein, linked to both Fas- and TNFR1-mediated apoptosis. |
| Q33267561 | RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling |
| Q37251620 | Reactive oxygen species mediate TNFR1 increase after TRPV1 activation in mouse DRG neurons |
| Q98386312 | Receptor tyrosine kinase ligands and inflammatory cytokines cooperatively suppress the fibrogenic activity in temporomandibular-joint-derived fibroblast-like synoviocytes via mitogen-activated protein kinase kinase/extracellular signal-regulated kin |
| Q28386983 | Regulation of IGF-I function by proinflammatory cytokines: at the interface of immunology and endocrinology |
| Q24321292 | Regulation of TNF-induced oxygen radical production in human neutrophils: role of delta-PKC |
| Q34456075 | Regulation of anti-Plasmodium immunity by a LITAF-like transcription factor in the malaria vector Anopheles gambiae |
| Q39700531 | Regulation of c-Rel nuclear localization by binding of Ca2+/calmodulin |
| Q35748219 | Regulation of the inflammatory profile of stromal cells in human breast cancer: prominent roles for TNF-α and the NF-κB pathway |
| Q37334658 | Release of nonmuscle myosin II from the cytosolic domain of tumor necrosis factor receptor 2 is required for target gene expression |
| Q84867370 | Retraction. Novel function of RECS1 as a negative regulator of TNF-alpha-induced NF-kappaB activation |
| Q28391879 | Role of TNF-alpha during central sensitization in preclinical studies |
| Q58122204 | Role of TNF-α in Regulating the Exercise Pressor Reflex in Rats With Femoral Artery Occlusion |
| Q36473677 | Role of TNFR1 in the innate airway hyperresponsiveness of obese mice |
| Q38299886 | Role of inflammatory cytokines in peripheral nerve injury |
| Q35436095 | SOD2-mediated adaptive responses induced by low-dose ionizing radiation via TNF signaling and amifostine. |
| Q35072031 | Selective role for tumor necrosis factor-α, but not interleukin-1 or Kupffer cells, in down-regulation of CYP3A11 and CYP3A25 in livers of mice infected with a noninvasive intestinal pathogen |
| Q33998787 | Serum concentrations of TNF α and its soluble receptors in patients with adrenal tumors treated by surgery |
| Q37042111 | Serum concentrations of markers of TNFalpha and Fas-mediated pathways and renal function in nonproteinuric patients with type 1 diabetes. |
| Q37834022 | Setting up TRAPS. |
| Q37679983 | Soluble TNFRp75 regulates host protective immunity against Mycobacterium tuberculosis |
| Q35884684 | Staphylococcus aureus: an introduction |
| Q46384476 | Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand. |
| Q58478806 | Subcellular localization and functional domain studies of DEFECTIVE KERNEL1 in maize and Arabidopsis suggest a model for aleurone cell fate specification involving CRINKLY4 and SUPERNUMERARY ALEURONE LAYER1 |
| Q40641343 | Suppression of TNF-alpha mediated apoptosis by EGF in TNF-alpha sensitive human cervical carcinoma cell line |
| Q37512035 | Switching leukemia cell phenotype between life and death |
| Q41813284 | Synergistic effect of pro-inflammatory TNFα and IL-17 in periostin mediated collagen deposition: potential role in liver fibrosis |
| Q38206507 | TNF blocking therapies and immunomonitoring in patients with inflammatory bowel disease |
| Q42490314 | TNF receptors in Kupffer cells |
| Q30453341 | TNF receptors regulate vascular homeostasis in zebrafish through a caspase-8, caspase-2 and P53 apoptotic program that bypasses caspase-3 |
| Q21093232 | TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease |
| Q30479123 | TNF superfamily: a growing saga of kidney injury modulators. |
| Q35159634 | TNF transactivation of EGFR stimulates cytoprotective COX-2 expression in gastrointestinal epithelial cells |
| Q35006572 | TNF-alpha and adipocyte biology |
| Q40642340 | TNF-alpha and leptin activate the alpha-isoform of class II phosphoinositide 3-kinase |
| Q51469597 | TNF-alpha interferes with lipid homeostasis and activates acute and proatherogenic processes. |
| Q46808390 | TNF-alpha is a mediator of the anti-inflammatory response in a human neonatal model of the non-septic shock syndrome |
| Q37120229 | TNF-alpha is a positive regulatory factor for human Vgamma2 Vdelta2 T cells |
| Q36121743 | TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice |
| Q44992766 | TNF-alpha regulates epithelial expression of MMP-9 and integrin alphavbeta6 during tumour promotion. A role for TNF-alpha in keratinocyte migration? |
| Q37322789 | TNF-α Autocrine Feedback Loops in Human Monocytes: The Pro- and Anti-Inflammatory Roles of the TNF-α Receptors Support the Concept of Selective TNFR1 Blockade In Vivo. |
| Q60682446 | TNF-α as an Autocrine Mediator and its Role in the Activation of Schwann Cells |
| Q44734604 | TNF-α downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A) receptors |
| Q61800300 | TNF-α enhances Th9 cell differentiation and antitumor immunity via TNFR2-dependent pathways |
| Q35542563 | TNFA Haplotype Genetic Testing Improves HLA in Estimating the Risk of Celiac Disease in Children |
| Q53923667 | TNFR2-mediated apoptosis and necrosis in cisplatin-induced acute renal failure. |
| Q64055695 | TNFα inhibitors as targets for protective therapies in MSA: a viewpoint |
| Q64095806 | TNFα is responsible for the canonical offspring number-size trade-off |
| Q38023207 | Targeted immunotherapy trials for idiopathic inflammatory myopathies |
| Q90216009 | Targeting tumor necrosis factor receptors in ankylosing spondylitis |
| Q38077697 | Targeting tumour necrosis factor-α in hypoxia and synaptic signalling |
| Q40851930 | The Association Between p38 MAPK-Mediated TNF-α/TNFR2 up-Regulation and 2-(4-Aminophenyl)-7-Methoxybenzothiazole-Induced Apoptosis in Human Leukemia U937 Cells |
| Q34291099 | The Epstein-Barr virus BZLF1 protein inhibits tumor necrosis factor receptor 1 expression through effects on cellular C/EBP proteins |
| Q26783012 | The Involvement of TNF-α in Cognitive Dysfunction Associated with Major Depressive Disorder: An Opportunity for Domain Specific Treatments |
| Q33187279 | The TNF family members BAFF and APRIL: the growing complexity |
| Q55316656 | The association between TNFR gene polymorphisms and the risk of Hepatitis B Virus-Related Liver Diseases in Chinese population. |
| Q39462585 | The cytomegaloviral protein pUL138 acts as potentiator of tumor necrosis factor (TNF) receptor 1 surface density to enhance ULb'-encoded modulation of TNF-α signaling |
| Q35103388 | The glomerulosclerosis of aging in females: contribution of the proinflammatory mesangial cell phenotype to macrophage infiltration. |
| Q92377580 | The role of TNF-α in rheumatoid arthritis: a focus on regulatory T cells |
| Q33614316 | The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis. |
| Q37981892 | The role of pharmacogenetics in nonmalignant gastrointestinal diseases |
| Q30463364 | The role of tumor necrosis factor receptor superfamily members in mammalian brain development, function and homeostasis |
| Q38445760 | Therapeutic non-toxic doses of TNF induce significant regression in TNFR2-p75 knockdown Lewis lung carcinoma tumor implants |
| Q40544635 | Thrombin and tumor necrosis factor alpha synergistically stimulate tissue factor expression in human endothelial cells: regulation through c-Fos and c-Jun |
| Q35207798 | Tissue glucocorticoid resistance/hypersensitivity syndromes. |
| Q60949502 | Transgenic mice overexpressing human TNF-α experience early onset spontaneous intervertebral disc herniation in the absence of overt degeneration |
| Q39922923 | Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy. |
| Q34588629 | Treatment of rheumatoid arthritis with tumour necrosis factor inhibitors |
| Q55115006 | Tumor Necrosis Factor and Interleukin-1β Modulate Synaptic Plasticity during Neuroinflammation. |
| Q90729963 | Tumor necrosis factor (TNF) modulates synaptic plasticity in a concentration-dependent manner through intracellular calcium stores |
| Q41881585 | Tumor necrosis factor (TNF)-receptor 1 and 2 mediate homeostatic synaptic plasticity of denervated mouse dentate granule cells |
| Q44755132 | Tumor necrosis factor activates CRE-binding protein through a p38 MAPK/MSK1 signaling pathway in endothelial cells |
| Q42828385 | Tumor necrosis factor alpha (TNFalpha) stimulates Map4k4 expression through TNFalpha receptor 1 signaling to c-Jun and activating transcription factor 2. |
| Q40058253 | Tumor necrosis factor alpha enhances nicotinic receptor up-regulation via a p38MAPK-dependent pathway |
| Q47594174 | Tumor necrosis factor alpha modulates airway smooth muscle function via the autocrine action of interferon beta |
| Q24336072 | Tumor necrosis factor alpha receptor- and Fas-associated FLASH inhibit transcriptional activity of the glucocorticoid receptor by binding to and interfering with its interaction with p160 type nuclear receptor coactivators |
| Q39668898 | Tumor necrosis factor alpha stimulates NMDA receptor activity in mouse cortical neurons resulting in ERK-dependent death |
| Q21284512 | Tumor necrosis factor alpha: a link between neuroinflammation and excitotoxicity |
| Q58052232 | Tumor necrosis factor receptor 2 M196R polymorphism in rheumatoid arthritis and osteoarthritis: relationship with sTNFR2 levels and clinical features |
| Q53534105 | Tumor necrosis factor-alpha activates nuclear factor-kappaB but does not regulate progesterone production in cultured human granulosa luteal cells. |
| Q37831189 | Tumor necrosis factor-alpha as a potential therapeutic target in idiopathic inflammatory myopathies |
| Q35197030 | Tumor necrosis factor-alpha at the crossroads of neuronal life and death during HIV-associated dementia |
| Q33727625 | Tumor necrosis factor-alpha causes release of cytosolic interleukin-18 from human neutrophils |
| Q37754950 | Tumor necrosis factor-alpha in severe corticosteroid-refractory asthma |
| Q73879531 | Tumor necrosis factor-alpha inhibits pre-osteoblast differentiation through its type-1 receptor |
| Q37087874 | Tumor necrosis factor-alpha is produced by dying retinal neurons and is required for Muller glia proliferation during zebrafish retinal regeneration |
| Q40144959 | Tumor necrosis factor-alpha stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression |
| Q45236643 | Tumor necrosis factor-alpha up-regulates the expression of beta1,4-galactosyltransferase I in primary human endothelial cells by mRNA stabilization |
| Q35592741 | Tumor necrosis factor-alpha: molecular and cellular mechanisms in skeletal pathology |
| Q34211709 | Tumor necrosis factor-{alpha} suppresses angiotensinogen expression through formation of a p50/p50 homodimer in human renal proximal tubular cells |
| Q51568269 | Tumor necrosis factor-α driven inflammation in alpha-1 antitrypsin deficiency: a new model of pathogenesis and treatment. |
| Q28475735 | Tumor necrosis factor-α regulates distinct molecular pathways and gene networks in cultured skeletal muscle cells |
| Q38526464 | Tumorigenicity of IL-1alpha- and IL-1beta-deficient fibrosarcoma cells. |
| Q35215812 | Tumour necrosis factor alpha: a potential target for the therapy of solid tumours. |
| Q42477683 | Tumour necrosis factor in the canine endometrium: an immunohistochemical study. |
| Q35485350 | Tumour necrosis factor receptor trafficking dysfunction opens the TRAPS door to pro-inflammatory cytokine secretion. |
| Q57265457 | Tumour necrosis factor-alpha receptor 1 and 2 polymorphisms in inflammatory bowel disease and their association with response to infliximab |
| Q36094915 | Tumour necrosis factor-α inhibition can stabilize disease in progressive vitiligo. |
| Q33655925 | Upregulation of tissue factor in monocytes by cleaved high molecular weight kininogen is dependent on TNF-alpha and IL-1beta |
| Q53657600 | β-1,4-Galactosyltransferase I involved in Schwann cells proliferation and apoptosis induced by tumor necrosis factor-alpha via the activation of MAP kinases signal pathways. |
Search more.