scholarly article | Q13442814 |
P2093 | author name string | Bravo R | |
Lacal JC | |||
Perona R | |||
Saniger L | |||
Montaner S | |||
Sánchez-Pérez I | |||
P433 | issue | 4 | |
P304 | page(s) | 463-475 | |
P577 | publication date | 1997-02-01 | |
P1433 | published in | Genes & Development | Q1524533 |
P1476 | title | Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins | |
P478 | volume | 11 |
Q34042089 | 1α,25-dihydroxyvitamin D3 ameliorates seawater aspiration-induced acute lung injury via NF-κB and RhoA/Rho kinase pathways |
Q28189959 | A Rho exchange factor mediates fMet-Leu-Phe-induced NF-kappaB activation in human peripheral blood monocytes |
Q36357411 | A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells |
Q41513620 | A mutation in Nischarin causes otitis media via LIMK1 and NF-κB pathways |
Q24533169 | A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways |
Q48039641 | A rho-associated protein kinase, ROKalpha, binds insulin receptor substrate-1 and modulates insulin signaling. |
Q45261051 | A role of STAT3 in Rho GTPase-regulated cell migration and proliferation |
Q38308950 | A serum response factor homologue is expressed in ectodermal tissues during development of the crustacean Artemia franciscana |
Q52605329 | A study of the key genes and inflammatory signaling pathways involved in HLA-B27-associated acute anterior uveitis families. |
Q43924647 | Actin' up: RhoB in cancer and apoptosis |
Q39784105 | Activated Rac1 requires gp130 for Stat3 activation, cell proliferation and migration |
Q35578258 | Activation of PAK by a bacterial type III effector EspG reveals alternative mechanisms of GTPase pathway regulation. |
Q30453215 | Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression. |
Q41860613 | Activation of RhoA and SAPK/JNK signalling pathways by the RhoA-specific exchange factor mNET1. |
Q39595937 | Activation of cJUN N-terminal kinase by herpes simplex virus type 1 enhances viral replication |
Q40715854 | Adhesion-related kinase repression of gonadotropin-releasing hormone gene expression requires Rac activation of the extracellular signal-regulated kinase pathway |
Q50881003 | Alpha-catulin, a Rho signalling component, can regulate NF-kappaB through binding to IKK-beta, and confers resistance to apoptosis. |
Q28297381 | Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged |
Q31877537 | An endogenous redox molecule, thioredoxin, regulates transactivation of epidermal growth factor receptor and activation of NF-kappaB by lysophosphatidic acid. |
Q40644510 | Angiopoietin-1 inhibits endothelial permeability, neutrophil adherence and IL-8 production |
Q38373127 | Angiotensin II and Cardiovascular-Renal Remodelling in Hypertension: Insights from a Human Model Opposite to Hypertension |
Q39825334 | Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways. |
Q36337932 | Anti-inflammatory effects of statins: clinical evidence and basic mechanisms |
Q33265941 | Anti-vascular agent Combretastatin A-4-P modulates hypoxia inducible factor-1 and gene expression |
Q38491199 | Apoptosis induced by Rac GTPase correlates with induction of FasL and ceramides production |
Q38046230 | Approaches to Ras signaling modulation and treatment of Ras-dependent disorders: a patent review (2007--present). |
Q47941184 | Atorvastatin reduces long pentraxin 3 expression in vascular cells by inhibiting protein geranylgeranylation |
Q22253427 | B-ind1, a novel mediator of Rac1 signaling cloned from sodium butyrate-treated fibroblasts |
Q36094307 | Bacterial cytotoxins: targeting eukaryotic switches |
Q37451109 | Bacterial toxins induce sustained mRNA expression of the silencing transcription factor klf2 via inactivation of RhoA and Rhophilin 1. |
Q43714923 | Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells |
Q33818687 | Breast cancer cell invasion mediated by Gα12 signaling involves expression of interleukins-6 and -8, and matrix metalloproteinase-2. |
Q38632892 | Breast cancer-associated gene 3 interacts with Rac1 and augments NF-κB signaling in vitro, but has no effect on RANKL-induced bone resorption in vivo |
Q73155209 | CL100/MKP-1 modulates JNK activation and apoptosis in response to cisplatin |
Q35002899 | Cadherin-11 regulates fibroblast inflammation |
Q30176009 | CdGAP, a novel proline-rich GTPase-activating protein for Cdc42 and Rac. |
Q33753610 | Cdc42 and aging of hematopoietic stem cells |
Q28236231 | Cdc42 in oncogenic transformation, invasion, and tumorigenesis |
Q27939243 | Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity |
Q39618338 | Cell stress and MEKK1-mediated c-Jun activation modulate NFkappaB activity and cell viability |
Q33800710 | Cell type-specific role for reactive oxygen species in nuclear factor-kappaB activation by interleukin-1. |
Q28513614 | Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development |
Q22003723 | Cellular functions of TC10, a Rho family GTPase: regulation of morphology, signal transduction and cell growth |
Q40809958 | Characterization of a functional serum response element in the Actin403 gene promoter from the crustacean Artemia franciscana. |
Q38297271 | Chemoattractant-stimulated NF-kappaB activation is dependent on the low molecular weight GTPase RhoA. |
Q37880077 | Chronic obstructive pulmonary disease: patho-physiology, current methods of treatment and the potential for simvastatin in disease management |
Q35570996 | Citron kinase, a RhoA effector, enhances HIV-1 virion production by modulating exocytosis |
Q40649906 | Constitutively Activated Rho Guanosine Triphosphatases Regulate the Growth and Morphology of Hairy Cell Leukemia Cells |
Q44650518 | Constitutively active Gq/11-coupled Receptors Enable Signaling by Co-expressed Gi/o-coupled Receptors |
Q34736520 | Critical activities of Rac1 and Cdc42Hs in skeletal myogenesis: antagonistic effects of JNK and p38 pathways |
Q36846434 | Critical role of Cdc42 in mediating endothelial barrier protection in vivo |
Q35964491 | Cross talk between the bombesin neuropeptide receptor and Sonic hedgehog pathways in small cell lung carcinoma. |
Q36168835 | Crucial role of Rho-nuclear factor-kappaB axis in angiotensin II-induced renal injury |
Q43780913 | Cycloprodigiosin hydrocloride suppresses tumor necrosis factor (TNF) alpha-induced transcriptional activation by NF-kappaB. |
Q28382965 | DLC1 suppresses NF-κB activity in prostate cancer cells due to its stabilizing effect on adherens junctions |
Q43597884 | Dbl and the Rho GTPases activate NF kappa B by I kappa B kinase (IKK)-dependent and IKK-independent pathways |
Q37649660 | Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-кB target genes in human breast cancer |
Q33960372 | Dependence of Dbl and Dbs transformation on MEK and NF-kappaB activation |
Q37619425 | Detection of enteric pathogens by the nodosome |
Q73691283 | Distinct functions of Rho and Rac are required for convergent extension during Xenopus gastrulation |
Q39092880 | Dual lipidation of the brain-specific Cdc42 isoform regulates its functional properties. |
Q51272863 | Effects of the Rho kinase inhibitor, hydroxyfasudil, on bladder dysfunction and inflammation in rats with HCl-induced cystitis. |
Q35192592 | Endothelial nitric oxide synthase deficient mice are protected from lipopolysaccharide induced acute lung injury. |
Q64914219 | Engineering of Human Corneal Endothelial Cells In Vitro. |
Q35995685 | Enhanced intrarenal oxidative stress and angiotensinogen in IgA nephropathy patients. |
Q28565494 | Eotaxin induces migration of RBL-2H3 mast cells via a Rac-ERK-dependent pathway |
Q42816126 | Expression of Rac1b stimulates NF-kappaB-mediated cell survival and G1/S progression |
Q73359138 | Expression of activated CDC42 induces T cell apoptosis in thymus and peripheral lymph organs via different pathways |
Q36328224 | Extracellular-regulated kinase activation and CAS/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix |
Q43628848 | Functional coupling between secretory and cytosolic phospholipase A2 modulates tumor necrosis factor-alpha- and interleukin-1beta-induced NF-kappa B activation |
Q35745964 | G Protein-Coupled Receptor and RhoA-Stimulated Transcriptional Responses: Links to Inflammation, Differentiation, and Cell Proliferation |
Q34359014 | G16-mediated activation of nuclear factor kappaB by the adenosine A1 receptor involves c-Src, protein kinase C, and ERK signaling |
Q24319756 | GEF-H1 mediated control of NOD1 dependent NF-kappaB activation by Shigella effectors |
Q24554337 | Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1 |
Q35128385 | Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts |
Q34244330 | Genome-wide analysis of Pax8 binding provides new insights into thyroid functions |
Q42817431 | Geranylgeranylated, but not farnesylated, RhoB suppresses Ras transformation of NIH-3T3 cells |
Q37828397 | Glutaminase: a hot spot for regulation of cancer cell metabolism? |
Q38256963 | Granule protein processing and regulated secretion in neutrophils |
Q35113720 | HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation |
Q84232214 | HMG-CoA reductase inhibitor simvastatin suppresses Toll-like receptor 2 ligand-induced activation of nuclear factor kappa B by preventing RhoA activation in monocytes from rheumatoid arthritis patients |
Q47964174 | HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation |
Q38121356 | Hematopoietic-specific Rho GTPases Rac2 and RhoH and human blood disorders |
Q35109696 | Hijacking Rho GTPases by protein toxins and apoptosis: molecular strategies of pathogenic bacteria. |
Q38153177 | How does cancer cell metabolism affect tumor migration and invasion? |
Q39595632 | Human immunodeficiency virus type 1 tat protein activates transcription factor NF-kappaB through the cellular interferon-inducible, double-stranded RNA-dependent protein kinase, PKR |
Q33714131 | IIp45, an insulin-like growth factor binding protein 2 (IGFBP-2) binding protein, antagonizes IGFBP-2 stimulation of glioma cell invasion |
Q35654383 | IQ Motif-Containing GTPase-Activating Protein 2 (IQGAP2) Is a Novel Regulator of Colonic Inflammation in Mice |
Q77581166 | Identification of a signaling pathway activated specifically in the somatodendritic compartment by a heparan sulfate that regulates dendrite growth |
Q44203329 | Identification of the LIM kinase-1 as a ceramide-regulated gene in renal mesangial cells |
Q30447293 | Identification of the deleted in liver cancer 1 gene, DLC1, as a candidate meningioma tumor suppressor. |
Q30540011 | Iloprost improves endothelial barrier function in lipopolysaccharide-induced lung injury |
Q33201904 | Impaired cytoskeletal organization and membrane integrity in lens fibers of a Rho GTPase functional knockout transgenic mouse |
Q89599348 | Impairment of Membrane Lipid Homeostasis by Bichalcone Analog TSWU-BR4 Attenuates Function of GRP78 in Regulation of the Oxidative Balance and Invasion of Cancer Cells |
Q30445152 | In response to protein load podocytes reorganize cytoskeleton and modulate endothelin-1 gene: implication for permselective dysfunction of chronic nephropathies |
Q53933222 | Increased expression of anti-apoptosis genes in peripheral blood cells from patients with paroxysmal nocturnal hemoglobinuria. |
Q33257134 | Induction of cell cycle changes and modulation of apoptogenic/anti-apoptotic and extracellular signaling regulatory protein expression by water extracts of I'm-Yunity (PSP) |
Q34124356 | Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling |
Q37012573 | Inhibition of NF-kappaB activity by IkappaBbeta in association with kappaB-Ras |
Q46622473 | Inhibition of Rho-dependent pathways by Clostridium botulinum C3 protein induces a proinflammatory profile in microglia |
Q28365800 | Inhibition of cell transformation by sulindac sulfide is confined to specific oncogenic pathways |
Q35491663 | Inhibition of geranylgeranyl transferase-I decreases cell viability of HTLV-1-transformed cells |
Q97419380 | Inhibition of leucine-rich repeats and calponin homology domain containing 1 accelerates microglia-mediated neuroinflammation in a rat traumatic spinal cord injury model |
Q43882525 | Inhibition of protein geranylgeranylation and RhoA/RhoA kinase pathway induces apoptosis in human endothelial cells |
Q33872322 | Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway |
Q41024128 | Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling |
Q40923131 | Involvement of NH(2)-terminal sequences in the negative regulation of Vav signaling and transforming activity |
Q35545301 | Involvement of Rho family GTPases in p19Arf- and p53-mediated proliferation of primary mouse embryonic fibroblasts |
Q64103582 | KLF4 activates NFκB signaling and esophageal epithelial inflammation via the Rho-related GTP-binding protein RHOF |
Q35641026 | Kaposi's sarcoma-associated herpesvirus microRNAs repress breakpoint cluster region protein expression, enhance Rac1 activity, and increase in vitro angiogenesis |
Q37349989 | KiSS1 suppresses TNFalpha-induced breast cancer cell invasion via an inhibition of RhoA-mediated NF-kappaB activation. |
Q77993726 | Lack of c-Jun activity increases survival to cisplatin |
Q38739496 | Leucine Zipper Down-regulated in Cancer-1 (LDOC1) interacts with Guanine nucleotide binding protein-like 3-like (GNL3L) to modulate Nuclear Factor-kappa B (NF-κB) signaling during cell proliferation. |
Q44614910 | Lovastatin causes sensitization of HeLa cells to ionizing radiation‐induced apoptosis by the abrogation of G2 blockage |
Q38328981 | Lysophosphatidic acid activates NF-kappaB in fibroblasts. A requirement for multiple inputs |
Q38044174 | Lysophospholipid receptor activation of RhoA and lipid signaling pathways |
Q35055504 | MDA-9/syntenin is essential for factor VIIa-induced signaling, migration, and metastasis in melanoma cells |
Q51630242 | Macrophages from lupus-prone MRL mice are characterized by abnormalities in Rho activity, cytoskeletal organization, and adhesiveness to extracellular matrix proteins. |
Q38132108 | Mal, more than a bridge to MyD88. |
Q28505657 | Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation |
Q39574466 | Mas oncogene signaling and transformation require the small GTP-binding protein Rac |
Q38330900 | Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase |
Q44492984 | Mechanisms of Bcr-Abl-mediated NF-kappaB/Rel activation |
Q41785271 | Melanoma cell migration to type IV collagen requires activation of NF-kappaB |
Q36304167 | Metabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth |
Q36708704 | MicroRNA-31 sensitizes human breast cells to apoptosis by direct targeting of protein kinase C epsilon (PKCepsilon). |
Q36780182 | Mixed lineage kinases (MLKs): a role in dendritic cells, inflammation and immunity? |
Q24554281 | Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex |
Q35619856 | Modulation of HIV-1 replication by a novel RhoA effector activity |
Q35565668 | Modulation of NFAT-dependent gene expression by the RhoA signaling pathway in T cells |
Q36561736 | Multifaceted role of Rho proteins in angiogenesis |
Q46037226 | Myeloid Notch1 Deficiency Activates RhoA/ROCK Pathway and Aggravates Hepatocellular Damage In Mouse Ischemic Livers. |
Q73916916 | NF-kappaB (p65/RelA) as a regulator of TNFalpha-mediated ML-1 cell differentiation |
Q34088808 | NF-kappaB activation in response to toxical and therapeutical agents: role in inflammation and cancer treatment |
Q33699422 | NF-kappaB and apoptosis in mammary epithelial cells |
Q34225148 | NF-kappaB and cell-cycle regulation: the cyclin connection |
Q28570506 | NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival |
Q54941244 | NFkB hyperactivation causes invasion of esophageal squamous cell carcinoma with EGFR overexpression and p120-catenin down-regulation. |
Q40397344 | NK cells are biologic and biochemical targets of 6-mercaptopurine in Crohn's disease patients |
Q92987394 | NMIIA promotes tumor growth and metastasis by activating the Wnt/β-catenin signaling pathway and EMT in pancreatic cancer |
Q40077398 | NOD1 and NOD2: Beyond Peptidoglycan Sensing. |
Q24315893 | Negative regulation of Rho family GTPases Cdc42 and Rac2 by homodimer formation |
Q40671067 | Neurotensin stimulates IL-8 expression in human colonic epithelial cells through Rho GTPase-mediated NF-kappa B pathways |
Q38981722 | New Aspects on Bacterial Effectors Targeting Rho GTPases |
Q38343521 | Number of expressed cancer/testis antigens identifies focal adhesion pathway genes as possible targets for multiple myeloma therapy. |
Q35067751 | Oncogenic K-Ras and loss of Smad4 mediate invasion by activating an EGFR/NF-κB Axis that induces expression of MMP9 and uPA in human pancreas progenitor cells |
Q33969205 | Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase |
Q88160419 | Oxidative stress as a possible mechanism of statin-induced myopathy |
Q41750986 | Oxygen radicals and signaling |
Q33670240 | PLCε, PKD1, and SSH1L transduce RhoA signaling to protect mitochondria from oxidative stress in the heart |
Q43660533 | PYK2 links G(q)alpha and G(13)alpha signaling to NF-kappa B activation. |
Q52963887 | Pathogenicity island-dependent activation of Rho GTPases Rac1 and Cdc42 in Helicobacter pylori infection. |
Q33797174 | Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases |
Q52668550 | Phosphorylation of glutaminase by PKCε is essential for its enzymatic activity and critically contributes to tumorigenesis. |
Q33782701 | Platelets and megakaryocytes contain functional nuclear factor-kappaB. |
Q33720590 | Potential drug targets: small GTPases that regulate leukocyte function |
Q74127433 | Potentiation of Rho-A-mediated lysophosphatidic acid activity by hyperinsulinemia |
Q36158964 | Prostanoid EP₁ receptors mediate up-regulation of the orphan nuclear receptor Nurr1 by cAMP-independent activation of protein kinase A, CREB and NF-κB. |
Q40565710 | Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kappaB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kappaB-regulated gene expression and up-regulation of apoptosis |
Q37036685 | Protein kinase D protects against oxidative stress-induced intestinal epithelial cell injury via Rho/ROK/PKC-delta pathway activation |
Q23918164 | Protein phosphorylation cascades associated with methamphetamine-induced glial activation |
Q36156141 | ROCK I-mediated activation of NF-kappaB by RhoB |
Q50066730 | ROCK as a therapeutic target for ischemic stroke. |
Q39089381 | ROCK2/rasHa co-operation induces malignant conversion via p53 loss, elevated NF-κB and tenascin C-associated rigidity, but p21 inhibits ROCK2/NF-κB-mediated progression |
Q26853214 | ROCKs as immunomodulators of stroke |
Q36779662 | Rac GTPase instructs nuclear factor-kappaB activation by conveying the SCF complex and IkBalpha to the ruffling membranes |
Q40230078 | Rac upregulates tissue inhibitor of metalloproteinase-1 expression by redox-dependent activation of extracellular signal-regulated kinase signaling. |
Q40927177 | Rac-dependent anti-apoptotic signaling by the insulin receptor cytoplasmic domain |
Q37371665 | Rac1 GTPase: a "Rac" of all trades. |
Q34695267 | Rac1 activity regulates proliferation of aggressive metastatic melanoma |
Q28216113 | Rac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-kappaB |
Q36310904 | Rac1 augments Wnt signaling by stimulating β-catenin-lymphoid enhancer factor-1 complex assembly independent of β-catenin nuclear import |
Q36733195 | Rac1 modulates acute and subacute genotoxin-induced hepatic stress responses, fibrosis and liver aging |
Q24303862 | Rac1 negatively regulates lipopolysaccharide-induced IL-23 p19 expression in human macrophages and dendritic cells and NF-kappaB p65 trans activation plays a novel role |
Q40803889 | Rac1 protects epithelial cells against anoikis |
Q39159284 | Rac1 signaling protects monocytic AML cells expressing the MLL-AF9 oncogene from caspase-mediated apoptotic death |
Q40301555 | Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells |
Q38678046 | Rac1-mediated cardiac damage causes diastolic dysfunction in a mouse model of subacute doxorubicin-induced cardiotoxicity |
Q27316142 | Rac1-regulated endothelial radiation response stimulates extravasation and metastasis that can be blocked by HMG-CoA reductase inhibitors |
Q39456448 | Ral GTPases contribute to regulation of cyclin D1 through activation of NF-kappaB. |
Q34073399 | Ras and Rho GTPases: a family reunion |
Q37061781 | Ras and rheb signaling in survival and cell death |
Q36291656 | Ras-like family small GTPases genes in Nilaparvata lugens: Identification, phylogenetic analysis, gene expression and function in nymphal development |
Q31523965 | Ras-related GTPase Rhob represses NF-kappaB signaling |
Q33957447 | Reactive oxygen intermediate-dependent NF-kappaB activation by interleukin-1beta requires 5-lipoxygenase or NADPH oxidase activity |
Q22010208 | Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways |
Q44413736 | Reduction of serum C-reactive protein by statin therapy may reflect decreased isoprenylation of Rac-1, a mediator of the IL-6 signal transduction pathway |
Q74734362 | Reduction of tumor necrosis factor-alpha (TNF-alpha) related nuclear factor-kappaB (NF-kappaB) translocation but not inhibitor kappa-B (Ikappa-B)-degradation by Rho protein inhibition in human endothelial cells |
Q28566136 | Regulated shuttling of Slit-Robo-GTPase activating proteins between nucleus and cytoplasm during brain development |
Q44077300 | Regulation of GRIP1 and CBP Coactivator activity by Rho GDI modulates estrogen receptor transcriptional enhancement |
Q38325239 | Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cells |
Q48000569 | Regulation of TNF-alpha-induced reorganization of the actin cytoskeleton and cell-cell junctions by Rho, Rac, and Cdc42 in human endothelial cells |
Q22254209 | Regulation of Tiam1 nucleotide exchange activity by pleckstrin domain binding ligands |
Q42828450 | Regulation of c-myc expression by PDGF through Rho GTPases. |
Q37041713 | Regulation of endothelial nitric oxide synthase and postnatal angiogenesis by Rac1. |
Q38249102 | Regulation of hematopoietic stem cell aging by the small RhoGTPase Cdc42 |
Q40400674 | Regulation of p21-activated kinase-independent Rac1 signal transduction by nischarin |
Q40890957 | Regulation of proliferation and apoptosis by Ras and Rho GTPases through specific phospholipid-dependent signaling |
Q28208539 | Regulation of proto-Dbl by intracellular membrane targeting and protein stability |
Q28576263 | Rho A negatively regulates cytokine-mediated inducible nitric oxide synthase expression in brain-derived transformed cell lines: negative regulation of IKKalpha |
Q34612747 | Rho GTPase signalling pathways in the morphological changes associated with apoptosis. |
Q36903028 | Rho GTPase-activating bacterial toxins: from bacterial virulence regulation to eukaryotic cell biology |
Q29547740 | Rho GTPases and their effector proteins |
Q27003967 | Rho GTPases and their roles in cancer metabolism |
Q35537884 | Rho GTPases as therapeutic targets for the treatment of inflammatory diseases |
Q38119740 | Rho GTPases in neurodegeneration diseases |
Q92816177 | Rho GTPases in the Physiology and Pathophysiology of Peripheral Sensory Neurons |
Q26782005 | Rho GTPases: Novel Players in the Regulation of the DNA Damage Response? |
Q28257230 | Rho GTPases: functions and association with cancer |
Q24301188 | Rho kinase blockade prevents inflammation via nuclear factor kappa B inhibition: evidence in Crohn's disease and experimental colitis |
Q43530084 | Rho kinase inhibition attenuates LPS-induced renal failure in mice in part by attenuation of NF-kappaB p65 signaling. |
Q33802112 | Rho protein GTPases and their interactions with NFκB: crossroads of inflammation and matrix biology |
Q34149118 | Rho protein inactivation induced apoptosis of cultured human endothelial cells |
Q34180592 | Rho signals to cell growth and apoptosis |
Q90975446 | Rho-mediated signaling promotes BRAF inhibitor resistance in de-differentiated melanoma cells |
Q34869485 | RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts |
Q40114788 | RhoA biological activity is dependent on prenylation but independent of specific isoprenoid modification. |
Q42639509 | RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation. |
Q33649134 | RhoA interacts with the fusion glycoprotein of respiratory syncytial virus and facilitates virus-induced syncytium formation |
Q31052568 | RhoA of the Rho family small GTPases is essential for B lymphocyte development |
Q24310745 | RhoG signals in parallel with Rac1 and Cdc42 |
Q39697053 | STAT5a activation mediates the epithelial to mesenchymal transition induced by oncogenic RhoA |
Q34348449 | Searching new targets for anticancer drug design: the families of Ras and Rho GTPases and their effectors |
Q34412353 | Serine-71 phosphorylation of Rac1 modulates downstream signaling |
Q35546502 | Serum response factor function and dysfunction in smooth muscle |
Q41724478 | Signal transduction through NF-kappa B. |
Q33948297 | Simultaneous tyrosine and serine phosphorylation of STAT3 transcription factor is involved in Rho A GTPase oncogenic transformation |
Q39644202 | Simvastatin inhibits glucose-stimulated vascular smooth muscle cell migration involving increased expression of RhoB and a block of Ras/Akt signal |
Q38451651 | Small GTPase Rap1 regulates cell migration through regulation of small GTPase RhoA activity in response to transforming growth factor-β1. |
Q34704519 | SmgGDS regulates cell proliferation, migration, and NF-kappaB transcriptional activity in non-small cell lung carcinoma |
Q35365005 | Statin use and risk of pancreatic cancer: results from a large, clinic-based case-control study |
Q39012650 | Statins in anthracycline-induced cardiotoxicity: Rac and Rho, and the heartbreakers |
Q36259633 | Statins stimulate in vitro membrane FasL expression and lymphocyte apoptosis through RhoA/ROCK pathway in murine melanoma cells |
Q40711853 | Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves Rho family small GTPases |
Q54281504 | Suppressing the formation of lipid raft-associated Rac1/PI3K/Akt signaling complexes by curcumin inhibits SDF-1α-induced invasion of human esophageal carcinoma cells. |
Q33959056 | Suppression of Ras-induced apoptosis by the Rac GTPase |
Q55032216 | Suppression of phospho-p85α-GTP-Rac1 lipid raft interaction by bichalcone analog attenuates cancer cell invasion. |
Q37086576 | Supreme EnLIGHTenment: damage recognition and signaling in the mammalian UV response |
Q27335272 | Systemic simvastatin rescues retinal ganglion cells from optic nerve injury possibly through suppression of astroglial NF-κB activation |
Q24322063 | TIM, a Dbl-related protein, regulates cell shape and cytoskeletal organization in a Rho-dependent manner |
Q34542205 | TNF ligands and receptors--a matter of life and death |
Q34565473 | TNF receptor subtype signalling: differences and cellular consequences |
Q34807996 | Targeting mitochondrial glutaminase activity inhibits oncogenic transformation |
Q35892052 | Targeting of host-cell ubiquitin and ubiquitin-like pathways by bacterial factors |
Q45070460 | Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha |
Q55207637 | The Pharmacological Targets and Clinical Evidence of Natural Products With Anti-hepatic Inflammatory Properties. |
Q26864271 | The Rac1 hypervariable region in targeting and signaling: a tail of many stories |
Q39411440 | The Rho/ROCK pathway for lysophosphatidic acid-induced proteolytic enzyme expression and ovarian cancer cell invasion. |
Q36744824 | The Tumor-suppressive Small GTPase DiRas1 Binds the Noncanonical Guanine Nucleotide Exchange Factor SmgGDS and Antagonizes SmgGDS Interactions with Oncogenic Small GTPases |
Q36401482 | The Vav-Rac1 pathway in cytotoxic lymphocytes regulates the generation of cell-mediated killing |
Q38129243 | The cytotoxic necrotizing factor 1 from E. coli: a janus toxin playing with cancer regulators. |
Q87593562 | The diamond anniversary of tissue transglutaminase: a protein of many talents |
Q28190692 | The formin/diaphanous-related protein, FHOS, interacts with Rac1 and activates transcription from the serum response element |
Q24292225 | The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function |
Q33967934 | The insert region of Rac1 is essential for membrane ruffling but not cellular transformation |
Q35011136 | The interferon-gamma-induced GTPase, mGBP-2, inhibits tumor necrosis factor alpha (TNF-alpha) induction of matrix metalloproteinase-9 (MMP-9) by inhibiting NF-kappaB and Rac protein |
Q36515597 | The intestinal microbiota dysbiosis and Clostridium difficile infection: is there a relationship with inflammatory bowel disease? |
Q35595431 | The many roles of statins in ischemic stroke |
Q35946550 | The nuclear factor kappaB-activator gene PLEKHG5 is mutated in a form of autosomal recessive lower motor neuron disease with childhood onset |
Q34594213 | The role of Rho GTPases in disease development |
Q28608947 | The small GTP-binding protein Cdc42 is required for nerve growth factor withdrawal-induced neuronal death |
Q30989694 | The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways |
Q34695835 | Thrombin induces NF-kappaB activation and IL-8/CXCL8 expression in lung epithelial cells by a Rac1-dependent PI3K/Akt pathway |
Q30413746 | Thrombin receptor and RhoA mediate cell proliferation through integrins and cysteine-rich protein 61. |
Q39759604 | Thyroid hormone antagonizes tumor necrosis factor-alpha signaling in pituitary cells through the induction of dual specificity phosphatase 1. |
Q28362213 | Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA |
Q40819427 | Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway |
Q34296477 | Toll-like receptors and innate immunity. |
Q40329297 | Transcriptomal profiling of the cellular transformation induced by Rho subfamily GTPases |
Q34033409 | Tumor lymphangiogenesis and metastasis to lymph nodes induced by cancer cell expression of podoplanin |
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