| scholarly article | Q13442814 |
| P50 | author | Paulo Matos | Q39965031 |
| Peter Jordan | Q39965078 | ||
| P2093 | author name string | John G Collard | |
| P2860 | cites work | IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling | Q24290667 |
| Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI | Q24292355 | ||
| CAS/Crk coupling serves as a "molecular switch" for induction of cell migration | Q24311510 | ||
| The Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formation | Q24313611 | ||
| Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation | Q24650561 | ||
| Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding | Q24674800 | ||
| The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI | Q27621179 | ||
| Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI | Q27621400 | ||
| Structure of the TPR domain of p67phox in complex with Rac.GTP | Q27628646 | ||
| Rho GTPases and the actin cytoskeleton | Q27860579 | ||
| Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product | Q28114879 | ||
| A brain serine/threonine protein kinase activated by Cdc42 and Rac1 | Q28249559 | ||
| Characterization of a Rac1- and RhoGDI-associated lipid kinase signaling complex | Q28567098 | ||
| Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav | Q28646540 | ||
| The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts | Q29042060 | ||
| Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs | Q29547308 | ||
| Rho GTPases control polarity, protrusion, and adhesion during cell movement | Q29614244 | ||
| An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1 | Q29614256 | ||
| The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway | Q29614258 | ||
| RHO-GTPases and cancer | Q29616099 | ||
| Guanine nucleotide exchange factors for Rho GTPases: turning on the switch | Q29618403 | ||
| Rac recruits high-affinity integrin alphavbeta3 to lamellipodia in endothelial cell migration | Q32084197 | ||
| Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway | Q33872322 | ||
| Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors | Q33883572 | ||
| Rho-family GTPases in cadherin-mediated cell-cell adhesion | Q34457173 | ||
| Spatio-temporal regulation of Rac1 localization and lamellipodia dynamics during epithelial cell-cell adhesion | Q36015668 | ||
| Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b | Q38310978 | ||
| Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase | Q38330900 | ||
| NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition | Q39445143 | ||
| Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells | Q40021756 | ||
| Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior | Q40915141 | ||
| Inhibition of invasion of epithelial cells by Tiam1-Rac signaling | Q41075588 | ||
| Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells | Q41075647 | ||
| Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function. | Q42436011 | ||
| Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins | Q42803708 | ||
| Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition | Q42919170 | ||
| Redox-dependent downregulation of Rho by Rac. | Q44323617 | ||
| Small GTPase Rac1: structure, localization, and expression of the human gene. | Q47817251 | ||
| A Rac1 effector site controlling mitogenesis through superoxide production | Q47860128 | ||
| Dissociation of GDP dissociation inhibitor and membrane translocation are required for efficient activation of Rac by the Dbl homology-pleckstrin homology region of Tiam | Q50337050 | ||
| Rho GTPases are over-expressed in human tumors. | Q53423587 | ||
| Rac "insert region" is a novel effector region that is implicated in the activation of NADPH oxidase, but not PAK65 | Q71245916 | ||
| Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1 | Q77649221 | ||
| P433 | issue | 50 | |
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 7 | |
| P304 | page(s) | 50442-50448 | |
| P577 | publication date | 2003-09-23 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling | |
| P478 | volume | 278 |
| Q40033262 | Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process |
| Q60907791 | Activated Rho GTPases in Cancer-The Beginning of a New Paradigm |
| Q43227064 | Alternate transcription of the Toll-like receptor signaling cascade |
| Q27642578 | Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase |
| Q52564290 | Alternative-splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics. |
| Q39825334 | Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways. |
| Q60044942 | Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma |
| Q22242922 | Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability |
| Q37214445 | Deregulation of Rho GTPases in cancer |
| Q35762816 | Epithelial-mesenchymal transition: general principles and pathological relevance with special emphasis on the role of matrix metalloproteinases |
| Q24646801 | Evolution of the Rho family of ras-like GTPases in eukaryotes |
| Q42816126 | Expression of Rac1b stimulates NF-kappaB-mediated cell survival and G1/S progression |
| Q50204378 | Fast-cycling Rho GTPases |
| Q33727178 | Fibrosis and cancer: do myofibroblasts come also from epithelial cells via EMT? |
| Q36567588 | Ibuprofen inhibits colitis-induced overexpression of tumor-related Rac1b |
| Q90043589 | Inflammatory Microenvironment Modulation of Alternative Splicing in Cancer: A Way to Adapt |
| Q39194138 | Insufficient ability of Rac1b to perturb cystogenesis |
| Q37590130 | Involvement of hnRNP A1 in the matrix metalloprotease-3-dependent regulation of Rac1 pre-mRNA splicing. |
| Q24633879 | Matrix metalloproteinase induction of Rac1b, a key effector of lung cancer progression |
| Q33915005 | Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer |
| Q34103467 | Matrix metalloproteinase-induced genomic instability |
| Q36857798 | Matrix metalloproteinase-induced malignancy in mammary epithelial cells |
| Q40387534 | Mechanisms of statin-mediated inhibition of small G-protein function |
| Q34418858 | Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes |
| Q47095199 | Negative regulation of TGF-β1-induced MKK6-p38 and MEK-ERK signalling and epithelial-mesenchymal transition by Rac1b |
| Q92162410 | Networks of mRNA Processing and Alternative Splicing Regulation in Health and Disease |
| Q24530809 | Non-EST based prediction of exon skipping and intron retention events using Pfam information |
| Q28238313 | Nup214-Nup88 nucleoporin subcomplex is required for CRM1-mediated 60 S preribosomal nuclear export |
| Q35049674 | Perturbation of cytoskeleton dynamics by the opposing effects of Rac1 and Rac1b |
| Q37661658 | Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells |
| Q26798154 | Posttranscriptional Regulation of Splicing Factor SRSF1 and Its Role in Cancer Cell Biology |
| Q46939939 | Purification and biochemical properties of Rac1, 2, 3 and the splice variant Rac1b |
| Q61805780 | RAC1B: A Rho GTPase with Versatile Functions in Malignant Transformation and Tumor Progression |
| Q36289839 | RAC1b overexpression stimulates proliferation and NF-kB-mediated anti-apoptotic signaling in thyroid cancer cells |
| Q33757116 | ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-kB-dependent activation of Snail |
| Q21245504 | Rac and Rho GTPases in cancer cell motility control |
| Q90363458 | Rac1 Signaling: From Intestinal Homeostasis to Colorectal Cancer Metastasis |
| Q38839225 | Rac1 in human diseases: The therapeutic potential of targeting Rac1 signaling regulatory mechanisms |
| Q37275178 | Rac1 signaling modulates BCL-6-mediated repression of gene transcription. |
| Q36228634 | Rac1 signalling modulates a STAT5/BCL-6 transcriptional switch on cell-cycle-associated target gene promoters |
| Q40301555 | Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells |
| Q29618122 | Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability |
| Q38790849 | Rac1b enhances cell survival through activation of the JNK2/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways |
| Q38365383 | Rac1b negatively regulates TGF-β1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling |
| Q38334837 | Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation |
| Q40400674 | Regulation of p21-activated kinase-independent Rac1 signal transduction by nischarin |
| Q28257230 | Rho GTPases: functions and association with cancer |
| Q33802112 | Rho protein GTPases and their interactions with NFκB: crossroads of inflammation and matrix biology |
| Q35741503 | Role of Rac1 in regulation of NOX5-S function in Barrett's esophageal adenocarcinoma cells |
| Q51193182 | SPSB1-mediated HnRNP A1 ubiquitylation regulates alternative splicing and cell migration in EGF signaling. |
| Q33655532 | Sanguinarine inhibits Rac1b-rendered cell survival enhancement by promoting apoptosis and blocking proliferation |
| Q34412353 | Serine-71 phosphorylation of Rac1 modulates downstream signaling |
| Q38166254 | Small Rho GTPases in the control of cell shape and mobility |
| Q40068834 | Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases. |
| Q89679156 | TNFα-mediated activation of NF-κB downregulates sodium-iodide symporter expression in thyroid cells |
| Q33911263 | The 19-amino acid insertion in the tumor-associated splice isoform Rac1b confers specific binding to p120 catenin |
| Q92082452 | The Intrinsic GDP/GTP Exchange Activities of Cdc42 and Rac1 Are Critical Determinants for Their Specific Effects on Mobilization of the Actin Filament System |
| Q89472949 | The Rac1 splice form Rac1b favors mouse colonic mucosa regeneration and contributes to intestinal cancer progression |
| Q24596918 | The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis |
| Q38215534 | The importance of matrix metalloproteinase-3 in respiratory disorders |
| Q38788923 | The role of TGF-β and its crosstalk with RAC1/RAC1b signaling in breast and pancreas carcinoma |
| Q38846822 | The role of small GTPases of the Rho/Rac family in TGF-β-induced EMT and cell motility in cancer |
| Q42805619 | Three-way translocation involves MLL, MLLT3, and a novel cell cycle control gene, FLJ10374, in the pathogenesis of acute myeloid leukemia with t(9;11;19)(p22;q23;p13.3). |
| Q36430125 | Tumor cell expression of MMP3 as a prognostic factor for poor survival in pancreatic, pulmonary, and mammary carcinoma |
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