| scholarly article | Q13442814 |
| P50 | author | Peter D'Eustachio | Q46921437 |
| P2093 | author name string | G Murphy | |
| D Michaelson | |||
| M Rush | |||
| M R Philips | |||
| J Silletti | |||
| P2860 | cites work | Regulation of epidermal growth factor receptor traffic by the small GTPase rhoB | Q22010605 |
| RhoGDIgamma: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas | Q24314694 | ||
| Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum | Q24321665 | ||
| Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line | Q24634571 | ||
| Intracellular localization of the P21rho proteins | Q24642838 | ||
| Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI | Q27621400 | ||
| The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors | Q27860467 | ||
| The small GTP-binding protein rac regulates growth factor-induced membrane ruffling | Q27861063 | ||
| Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia | Q27861126 | ||
| Endoplasmic reticulum membrane localization of Rce1p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavage | Q27931598 | ||
| Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi | Q28140190 | ||
| Mammalian Cdc42 is a brefeldin A-sensitive component of the Golgi apparatus | Q95826484 | ||
| Differential properties of D4/LyGDI versus RhoGDI: phosphorylation and rho GTPase selectivity | Q28263808 | ||
| All ras proteins are polyisoprenylated but only some are palmitoylated | Q28270312 | ||
| The Dbl family of oncogenes | Q28288875 | ||
| The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF | Q28292490 | ||
| RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG | Q28298035 | ||
| Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2 | Q28609631 | ||
| Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs | Q29547308 | ||
| ER-to-Golgi transport visualized in living cells | Q29547526 | ||
| Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases | Q29614245 | ||
| The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway | Q29614258 | ||
| Effectors for the Rho GTPases | Q33536478 | ||
| Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins. | Q33785693 | ||
| Ultrastructural localization of ras-related proteins using epitope-tagged plasmids | Q34293776 | ||
| GAPs for rho-related GTPases | Q34319579 | ||
| The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation | Q34452174 | ||
| Selective alterations in biosynthetic and endocytic protein traffic in Madin-Darby canine kidney epithelial cells expressing mutants of the small GTPase Rac1. | Q34672405 | ||
| Protein isoprenylation and methylation at carboxyl-terminal cysteine residues | Q35671041 | ||
| Modulation of endocytic traffic in polarized Madin-Darby canine kidney cells by the small GTPase RhoA. | Q36957463 | ||
| Protein-DNA interactions at a drug-responsive element of the human apolipoprotein A-I gene | Q38352112 | ||
| H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway | Q39451813 | ||
| Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells | Q40918582 | ||
| Polarized distribution of endogenous Rac1 and RhoA at the cell surface | Q40941434 | ||
| Nuclear translocation of RhoA mediates the mitogen-induced activation of phospholipase D involved in nuclear envelope signal transduction | Q41127011 | ||
| Endosome dynamics regulated by a Rho protein. | Q41145924 | ||
| Regulation of receptor-mediated endocytosis by Rho and Rac. | Q41185352 | ||
| A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane | Q41718569 | ||
| The gamma-subunit of the coatomer complex binds Cdc42 to mediate transformation | Q42800432 | ||
| Differential translocation of rho family GTPases by lysophosphatidic acid, endothelin-1, and platelet-derived growth factor | Q42806034 | ||
| An essential role for Rac in Ras transformation | Q42829150 | ||
| Post-translational modifications of the C-terminal region of the rho protein are important for its interaction with membranes and the stimulatory and inhibitory GDP/GTP exchange proteins. | Q44672657 | ||
| Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins. | Q46887698 | ||
| Unique in vivo associations with SmgGDS and RhoGDI and different guanine nucleotide exchange activities exhibited by RhoA, dominant negative RhoA(Asn-19), and activated RhoA(Val-14). | Q54039001 | ||
| Inhibition of protein palmitoylation, raft localization, and T cell signaling by 2-bromopalmitate and polyunsaturated fatty acids. | Q54067088 | ||
| Characterization of the interaction between RhoGDI and Cdc42Hs using fluorescence spectroscopy. | Q54590060 | ||
| Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils | Q57731072 | ||
| Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1 | Q59053220 | ||
| Regulation of binding of rhoB p20 to membranes by its specific regulatory protein, GDP dissociation inhibitor | Q67983251 | ||
| Subcellular distribution and membrane association of Rho-related small GTP-binding proteins in kidney cortex | Q72005945 | ||
| Translocation of p21rac2 from cytosol to plasma membrane is neither necessary nor sufficient for neutrophil NADPH oxidase activity | Q72223310 | ||
| Dissociation of LPA-induced cytoskeletal contraction from stress fiber formation by differential localization of RhoA | Q73970772 | ||
| Regulation of Rho protein binding to membranes by rhoGDI: inhibition of releasing activity by physiological ionic conditions | Q78060007 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 111-26 | |
| P577 | publication date | 2001-01-08 | |
| P1433 | published in | Journal of Cell Biology | Q1524550 |
| P1476 | title | Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding | |
| P478 | volume | 152 |
| Q24339259 | 14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibit G proteins |
| Q64263430 | A PKA/cdc42 Signaling Axis Restricts Angiogenic Sprouting by Regulating Podosome Rosette Biogenesis and Matrix Remodeling |
| Q27302353 | A RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cells |
| Q44170732 | A cell-specific, prenylation-independent mechanism regulates targeting of type II RACs |
| Q27332265 | A density-dependent switch drives stochastic clustering and polarization of signaling molecules |
| Q28116254 | A human short open reading frame (sORF)-encoded polypeptide that stimulates DNA end joining |
| Q27334658 | A new genetically encoded single-chain biosensor for Cdc42 based on FRET, useful for live-cell imaging |
| Q40105856 | A novel role of Rac1 GTPase in JCV T-antigen-mediated beta-catenin stabilization |
| Q30495640 | A novel statin-mediated "prenylation block-and-release" assay provides insight into the membrane targeting mechanisms of small GTPases |
| Q42797811 | A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells |
| Q34408453 | A novel testis-specific GTPase serves as a link to proteasome biogenesis: functional characterization of RhoS/RSA-14-44 in spermatogenesis |
| Q24299466 | A palmitoylation switch mechanism regulates Rac1 function and membrane organization. |
| Q39992418 | A quantitative fluorometric approach for measuring the interaction of RhoGDI with membranes and Rho GTPases |
| Q39887636 | Actin can reorganize into podosomes in aortic endothelial cells, a process controlled by Cdc42 and RhoA. |
| Q43924647 | Actin' up: RhoB in cancer and apoptosis |
| Q42369182 | Activating Transcription Factor 4 (ATF4) modulates Rho GTPase levels and function via regulation of RhoGDIα. |
| Q36323206 | Activity of Rho-family GTPases during cell division as visualized with FRET-based probes |
| Q40615070 | An activating mutant of Rac1 that fails to interact with Rho GDP-dissociation inhibitor stimulates membrane ruffling in mammalian cells |
| Q34562111 | An improved Ras sensor for highly sensitive and quantitative FRET-FLIM imaging |
| Q27348271 | An isoprenylation and palmitoylation motif promotes intraluminal vesicle delivery of proteins in cells from distant species |
| Q37327005 | Androgen control of cell proliferation and cytoskeletal reorganization in human fibrosarcoma cells: role of RhoB signaling. |
| Q33821699 | Approaches to studying cellular signaling: a primer for morphologists |
| Q50513586 | Aquaporin 9 phosphorylation mediates membrane localization and neutrophil polarization. |
| Q28366139 | Arabidopsis thaliana Rop GTPases are localized to tips of root hairs and control polar growth |
| Q90573431 | Arf6 regulates RhoB subcellular localization to control cancer cell invasion |
| Q39645746 | Arg188 drives RhoC membrane binding |
| Q52594365 | Argosomes: membrane fragments on the run. |
| Q34360604 | Assembly and mechanosensory function of focal contacts |
| Q35050467 | Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5 |
| Q33794593 | Auxin Signaling in Regulation of Plant Translation Reinitiation |
| Q36394017 | Biochemical analyses of the Wrch atypical Rho family GTPases |
| Q34328046 | Biochemical characterization of the Yersinia YopT protease: cleavage site and recognition elements in Rho GTPases |
| Q33292257 | Bioluminescence resonance energy transfer identify scaffold protein CNK1 interactions in intact cells |
| Q41177591 | Biosensors for characterizing the dynamics of rho family GTPases in living cells |
| Q41976275 | C-terminal di-arginine motif of Cdc42 protein is essential for binding to phosphatidylinositol 4,5-bisphosphate-containing membranes and inducing cellular transformation |
| Q106519007 | CDC42 translocates to the endoplasmic reticulum membrane |
| Q36734480 | Cdc42 and Cellular Polarity: Emerging Roles at the Golgi |
| Q30497314 | Cdc42 and Gsk3 modulate the dynamics of radial glial growth, inter-radial glial interactions and polarity in the developing cerebral cortex |
| Q30160092 | Cdc42 induces activation loop phosphorylation and membrane targeting of mixed lineage kinase 3. |
| Q34439671 | Cdc42 localization and cell polarity depend on membrane traffic |
| Q37031442 | Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis. |
| Q39538510 | Cdc42p is activated during vacuole membrane fusion in a sterol-dependent subreaction of priming |
| Q44922057 | Cell migration and signaling specificity is determined by the phosphatidylserine recognition motif of Rac1. |
| Q57364636 | Chapter 8 Insulin Signaling and Caveolae |
| Q40641826 | Characterization of YopT effects on Rho GTPases in Yersinia enterocolitica-infected cells. |
| Q40659447 | Characterization of human palmitoyl-acyl transferase activity using peptides that mimic distinct palmitoylation motifs |
| Q44313342 | Cholesterol distribution in the Golgi complex of DITNC1 astrocytes is differentially altered by fresh and aged amyloid beta-peptide-(1-42). |
| Q28580961 | Cloning of rat ARHGAP4/C1, a RhoGAP family member expressed in the nervous system that colocalizes with the Golgi complex and microtubules |
| Q47961886 | Cloning of the human RHOB gene promoter: characterization of a VNTR sequence that affects transcriptional activity |
| Q38334527 | Clostridium difficile toxin A induces expression of the stress-induced early gene product RhoB. |
| Q30539004 | Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor. |
| Q28239633 | Comparative analysis of the role of small G proteins in cell migration and cell death: cytoprotective and promigratory effects of RalA |
| Q34694782 | Compartmentalized signaling of Ras in fission yeast |
| Q28484932 | Computational analysis of Rho GTPase cycling |
| Q37441470 | Concordance and interaction of guanine nucleotide dissociation inhibitor (RhoGDI) with RhoA in oogenesis and early development of the sea urchin |
| Q44356627 | Control of the G-protein cascade dynamics by GDP dissociation inhibitors |
| Q35127933 | Control of vesicular trafficking by Rho GTPases |
| Q47097106 | Corrected and Republished from: Activation Status-Coupled Transient S-Acylation Determines Membrane Partitioning of a Plant Rho-Related GTPase |
| Q35870712 | Coxiella burnetii Phagocytosis Is Regulated by GTPases of the Rho Family and the RhoA Effectors mDia1 and ROCK |
| Q28083368 | Current perspective on protein S-acylation in plants: more than just a fatty anchor? |
| Q39081937 | Cyclic AMP regulates the migration and invasion potential of human pancreatic cancer cells |
| Q48045598 | Cytoskeletal adaptivity regulates T cell receptor signaling. |
| Q39645629 | Cytosolic Ras supports eye development in Drosophila |
| Q28535581 | Decoupling polarization of the Golgi apparatus and GM1 in the plasma membrane |
| Q39647962 | Defects in cytokinesis, actin reorganization and the contractile vacuole in cells deficient in RhoGDI. |
| Q36320736 | Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway |
| Q40031657 | Design and optimization of genetically encoded fluorescent biosensors: GTPase biosensors |
| Q50713990 | Dictyostelium RacH regulates endocytic vesicular trafficking and is required for localization of vacuolin. |
| Q52447428 | Differential ability of proinflammatory and anti-inflammatory macrophages to perform macropinocytosis. |
| Q39622755 | Differential effects of prenylation and s-acylation on type I and II ROPS membrane interaction and function. |
| Q33604076 | Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling |
| Q30513084 | Diffusion, capture and recycling of SCAR/WAVE and Arp2/3 complexes observed in cells by single-molecule imaging. |
| Q40640840 | Directional motility induced by epidermal growth factor requires Cdc42. |
| Q41451621 | Disruption of RhoGDI and RhoA regulation by a Rac1 specificity switch mutant |
| Q24338658 | Dissecting the role of Rho-mediated signaling in contractile ring formation |
| Q24329196 | Distinct biological activities of C3 and ADP-ribosyltransferase-deficient C3-E174Q |
| Q90727783 | Distribution, dynamics and functional roles of phosphatidylserine within the cell |
| Q39335878 | Divergence of Rho residue 43 impacts GEF activity |
| Q28187402 | Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration |
| Q52576207 | Dual lipid modification of Arabidopsis Ggamma-subunits is required for efficient plasma membrane targeting. |
| Q39092880 | Dual lipidation of the brain-specific Cdc42 isoform regulates its functional properties. |
| Q37823095 | Dynamics of the Rho-family small GTPases in actin regulation and motility |
| Q37350008 | ECM-stimulated signaling and actin reorganization in embryonic corneal epithelia are Rho dependent |
| Q37472287 | Effects of constitutively active GTPases on fibroblast behavior |
| Q40071304 | Effects of lovastatin on Rho isoform expression, activity, and association with guanine nucleotide dissociation inhibitors |
| Q90196452 | Engineering Photorhabdus luminescens toxin complex (PTC) into a recombinant injection nanomachine |
| Q33307820 | Epigenetic regulation of RhoB loss of expression in lung cancer |
| Q52838429 | Erufosine increases RhoB expression in oral squamous carcinoma cells independent of its tumor suppressive mode of action - a short report. |
| Q40528901 | ExoS Rho GTPase-activating protein activity stimulates reorganization of the actin cytoskeleton through Rho GTPase guanine nucleotide disassociation inhibitor |
| Q35040895 | Expression loss and revivification of RhoB gene in ovary carcinoma carcinogenesis and development |
| Q38784164 | Expression of Tau Produces Aberrant Plasma Membrane Blebbing in Glial Cells Through RhoA-ROCK-Dependent F-Actin Remodeling. |
| Q28550544 | Extracting Diffusive States of Rho GTPase in Live Cells: Towards In Vivo Biochemistry |
| Q83225717 | Extraction of active RhoGTPases by RhoGDI regulates spatiotemporal patterning of RhoGTPases |
| Q42724551 | FKBP12 binds to acylated H-ras and promotes depalmitoylation |
| Q30813417 | FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions |
| Q36608782 | Fluorescence-based methods to image palmitoylated proteins |
| Q46330471 | Fluorescent labeling of proteins in living cells using the FKBP12 (F36V) tag. |
| Q38089133 | G12/13-dependent signaling of G-protein-coupled receptors: disease context and impact on drug discovery |
| Q27323626 | GDI-mediated cell polarization in yeast provides precise spatial and temporal control of Cdc42 signaling |
| Q43773500 | GEF at work: Vav in protruding filopodia |
| Q37010740 | GPS-Lipid: a robust tool for the prediction of multiple lipid modification sites |
| Q27302525 | GTP hydrolysis of TC10 promotes neurite outgrowth through exocytic fusion of Rab11- and L1-containing vesicles by releasing exocyst component Exo70 |
| Q24626495 | Gain-of-function mutations of ARHGAP31, a Cdc42/Rac1 GTPase regulator, cause syndromic cutis aplasia and limb anomalies |
| Q35388015 | Generation of a single chain antibody variable fragment (scFv) to sense selectively RhoB activation |
| Q35738213 | Genome-wide identification of Calcineurin B-Like (CBL) gene family of plants reveals novel conserved motifs and evolutionary aspects in calcium signaling events |
| Q42817431 | Geranylgeranylated, but not farnesylated, RhoB suppresses Ras transformation of NIH-3T3 cells |
| Q39257808 | Geranylgeranyltransferase I promotes human glioma cell growth through Rac1 membrane association and activation |
| Q34519891 | Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice |
| Q33628767 | HIV gp41 engages gC1qR on CD4+ T cells to induce the expression of an NK ligand through the PIP3/H2O2 pathway |
| Q30479101 | Helicobacter pylori CagA induces AGS cell elongation through a cell retraction defect that is independent of Cdc42, Rac1, and Arp2/3. |
| Q79176492 | Hematopoietic Cell Regulation by Rac1 and Rac2 Guanosine Triphosphatases |
| Q47344735 | High-content tripartite split-GFP cell-based assays to screen for modulators of small GTPase activation |
| Q27331922 | How cells integrate complex stimuli: the effect of feedback from phosphoinositides and cell shape on cell polarization and motility |
| Q27350493 | Human Mena associates with Rac1 small GTPase in glioblastoma cell lines |
| Q24337727 | Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity |
| Q28285153 | IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli |
| Q35120895 | IQGAP1 as signal integrator: Ca2+, calmodulin, Cdc42 and the cytoskeleton |
| Q28214384 | IQGAP1 is a component of Cdc42 signaling to the cytoskeleton |
| Q43151828 | Identification of a GTP-bound Rho specific scFv molecular sensor by phage display selection |
| Q30157925 | Identification of a bipartite focal adhesion localization signal in RhoU/Wrch-1, a Rho family GTPase that regulates cell adhesion and migration |
| Q28584989 | Identification of a novel prenyl and palmitoyl modification at the CaaX motif of Cdc42 that regulates RhoGDI binding |
| Q36907763 | Identifying network motifs that buffer front-to-back signaling in polarized neutrophils. |
| Q46795047 | Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid |
| Q38976628 | In vivo Rac/Rop localization as well as interaction with RhoGAP and RhoGDI in tobacco pollen tubes: analysis by low-level expression of fluorescent fusion proteins and bimolecular fluorescence complementation |
| Q30440155 | In vivo dynamics of Rac-membrane interactions |
| Q34116489 | In vivo rho GTPase-activating protein activity of Pseudomonas aeruginosa cytotoxin ExoS |
| Q40267571 | Inactivation of Rho GTPases by p190 RhoGAP reduces human pancreatic cancer cell invasion and metastasis |
| Q35009496 | Increased cytoplasmic localization of p27(kip1) and its modulation of RhoA activity during progression of chronic myeloid leukemia |
| Q39666360 | Induction of small G protein RhoB by non-genotoxic stress inhibits apoptosis and activates NF-κB. |
| Q28583531 | Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta |
| Q30503202 | Interaction of PAR-6 with CDC-42 is required for maintenance but not establishment of PAR asymmetry in C. elegans |
| Q28479259 | Interleukin-4 alters early phagosome phenotype by modulating class I PI3K dependent lipid remodeling and protein recruitment |
| Q63363430 | Intersectin-1 interacts with the golgin GCC88 to couple the actin network and Golgi architecture |
| Q47652910 | Intracellular mature IL-37 suppresses tumor metastasis via inhibiting Rac1 activation |
| Q33711312 | Investigation of the sequence and length dependence for cell-penetrating prenylated peptides |
| Q42812157 | Isoform-specific differences between Rap1A and Rap1B GTPases in the formation of endothelial cell junctions |
| Q30164079 | Isotype-specific degradation of Rac activated by the cytotoxic necrotizing factor 1. |
| Q40360081 | K-ras4B and prenylated proteins lacking "second signals" associate dynamically with cellular membranes |
| Q58804980 | KIF13A-regulated RhoB plasma membrane localization governs membrane blebbing and blebby amoeboid cell migration |
| Q28582557 | LIMK1 regulates Golgi dynamics, traffic of Golgi-derived vesicles, and process extension in primary cultured neurons |
| Q24669996 | Lipid Raft targeting of the TC10 amino terminal domain is responsible for disruption of adipocyte cortical actin |
| Q40018825 | Lipid and sulfur substituted prenylcysteine analogs as human Icmt inhibitors |
| Q30441963 | Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation |
| Q36938589 | Lipid signaling and the modulation of surface charge during phagocytosis |
| Q35205434 | Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1. |
| Q42202218 | Live imaging of cellular dynamics using a multi-imaging vector in single cells |
| Q24629206 | Local, persistent activation of Rho GTPases during plasticity of single dendritic spines |
| Q44915718 | Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils. |
| Q30476117 | Localized RhoA activation as a requirement for the induction of membrane ruffling |
| Q36182233 | Loss of GM130 in breast cancer cells and its effects on cell migration, invasion and polarity. |
| Q47616484 | Loss of RhoA promotes skin tumor formation and invasion by upregulation of RhoB. |
| Q40041094 | MAP1A light chain-2 interacts with GTP-RhoB to control epidermal growth factor (EGF)-dependent EGF receptor signaling |
| Q42502278 | Maintenance of CDC42 GDP-bound state by Rho-GDI inhibits MAP kinase activation by the exchange factor Ras-GRF. evidence for Ras-GRF function being inhibited by Cdc42-GDP but unaffected by CDC42-GTP. |
| Q35153478 | Membrane targeting of Rab GTPases is influenced by the prenylation motif |
| Q40801638 | Membrane targeting of a Rab GTPase that fails to associate with Rab escort protein (REP) or guanine nucleotide dissociation inhibitor (GDI). |
| Q34061239 | Membrane trafficking of heterotrimeric G proteins via the endoplasmic reticulum and Golgi |
| Q30439700 | Memo-RhoA-mDia1 signaling controls microtubules, the actin network, and adhesion site formation in migrating cells |
| Q35728305 | Mitochondrial Rac1 GTPase import and electron transfer from cytochrome c are required for pulmonary fibrosis. |
| Q38682208 | Molecular perturbation strategies to examine spatiotemporal features of Rho GEF and Rho GTPase activity in living cells. |
| Q37415239 | Multifunctional prenylated peptides for live cell analysis |
| Q42364777 | Multiple cellular proteins modulate the dynamics of K-ras association with the plasma membrane |
| Q24548672 | Multiple sequence elements facilitate Chp Rho GTPase subcellular location, membrane association, and transforming activity |
| Q90077305 | Nanomechanical insights: Amyloid beta oligomer-induced senescent brain endothelial cells |
| Q27322416 | Neuronal (bi)polarity as a self-organized process enhanced by growing membrane |
| Q37358214 | New insights into how the Rho guanine nucleotide dissociation inhibitor regulates the interaction of Cdc42 with membranes |
| Q35925311 | Nonpolarized signaling reveals two distinct modes of 3D cell migration |
| Q40011733 | Norwalk virus nonstructural protein p48 forms a complex with the SNARE regulator VAP-A and prevents cell surface expression of vesicular stomatitis virus G protein |
| Q24312395 | Nuclear Rho kinase, ROCK2, targets p300 acetyltransferase |
| Q37244862 | Nucleocytoplasmic shuttling of the adapter protein SH2B1beta (SH2-Bbeta) is required for nerve growth factor (NGF)-dependent neurite outgrowth and enhancement of expression of a subset of NGF-responsive genes |
| Q34037545 | Nucleophosmin1 is a negative regulator of the small GTPase Rac1. |
| Q46941432 | Oncogenic Vav1 induces Rac-dependent apoptosis via inhibition of Bcl-2 family proteins and collaborates with p53 deficiency to promote hematopoietic progenitor cell proliferation |
| Q50456908 | Opposing FlnA and FlnB interactions regulate RhoA activation in guiding dynamic actin stress fiber formation and cell spreading. |
| Q30738195 | Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells. |
| Q89860559 | P-REX1-Independent, Calcium-Dependent RAC1 Hyperactivation in Prostate Cancer |
| Q36630120 | PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane |
| Q55309370 | Parallels between single cell migration and barrier formation: The case of RhoB and Rac1 trafficking. |
| Q89430427 | Paxillin phosphorylation at serine 273 and its effects on Rac, Rho and adhesion dynamics |
| Q33408806 | Phosphatase of regenerating liver-3 localizes to cyto-membrane and is required for B16F1 melanoma cell metastasis in vitro and in vivo |
| Q35606814 | Phosphoinositides and Rho proteins spatially regulate actin polymerization to initiate and maintain directed movement in a one-dimensional model of a motile cell |
| Q36739944 | Phospholipase D activity regulates integrin-mediated cell spreading and migration by inducing GTP-Rac translocation to the plasma membrane |
| Q37233372 | Phospholipase D1 regulates lymphocyte adhesion via upregulation of Rap1 at the plasma membrane |
| Q48258682 | Phospholipid localization implies microglial morphology and function via Cdc42 in vitro |
| Q35905776 | Phosphorylation and Activation of RhoA by ERK in Response to Epidermal Growth Factor Stimulation. |
| Q36977651 | Phosphorylation of GTP dissociation inhibitor by PKA negatively regulates RhoA |
| Q28344277 | Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes |
| Q33348863 | Physcomitrella patens: a model to investigate the role of RAC/ROP GTPase signalling in tip growth |
| Q57986700 | Pivotal Advance: Phospholipids determine net membrane surface charge resulting in differential localization of active Rac1 and Rac2 |
| Q36119815 | Plasma membrane restricted RhoGEF activity is sufficient for RhoA-mediated actin polymerization |
| Q34287222 | Pleckstrin homology domain-mediated activation of the rho-specific guanine nucleotide exchange factor Dbs by Rac1. |
| Q33761889 | Polyisoprenylated cysteinyl amide inhibitors disrupt actin cytoskeleton organization, induce cell rounding and block migration of non-small cell lung cancer |
| Q36565073 | Positioning centrosomes and spindle poles: looking at the periphery to find the centre. |
| Q35550465 | Positive regulation of Rho GTPase activity by RhoGDIs as a result of their direct interaction with GAPs |
| Q81703538 | Post-prenylation-processing enzymes as new targets in oncogenesis |
| Q33734499 | Postprenylation CAAX processing is required for proper localization of Ras but not Rho GTPases |
| Q47223139 | Posttranslational Modifications of RAS Proteins. |
| Q39069181 | Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability |
| Q37384869 | Protein S-acylation in plants (Review). |
| Q26828492 | Protein lipid modifications and the regulation of ROP GTPase function |
| Q33361203 | Protein prenylation in islet β-cell function in health and diabetes: Putting the pieces of the puzzle together. |
| Q35868667 | Proteome analysis of cultivated vascular smooth muscle cells from a CADASIL patient. |
| Q47243831 | Pulmonary Endothelial Cell Apoptosis in Emphysema and Acute Lung Injury |
| Q106518964 | RAC1 translocates to the endoplasmic reticulum membrane |
| Q27675701 | RAC1P29S is a spontaneously activating cancer-associated GTPase |
| Q106518976 | RAC2 translocates to the ER membrane |
| Q42924833 | RETRACTED: Activation status-coupled transient S acylation determines membrane partitioning of a plant Rho-related GTPase |
| Q106520268 | RHOQ GTPase cycle |
| Q45622965 | RISAP is a TGN-associated RAC5 effector regulating membrane traffic during polar cell growth in tobacco. |
| Q92720720 | RNA-Binding Protein HuR Regulates Rac1 Nucleocytoplasmic Shuttling Through Nucleophosmin in the Intestinal Epithelium |
| Q36954083 | ROCK and Rho: biochemistry and neuronal functions of Rho-associated protein kinases |
| Q45124244 | Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain. |
| Q34452485 | Rac GTPase-activating protein (Rac GAP) α1-Chimaerin undergoes proteasomal degradation and is stabilized by diacylglycerol signaling in neurons. |
| Q43918731 | Rac activation induces NADPH oxidase activity in transgenic COSphox cells, and the level of superoxide production is exchange factor-dependent. |
| Q92220262 | Rac activation is key to cell motility and directionality: An experimental and modelling investigation |
| Q30481827 | Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division |
| Q42219465 | Rac1 activation inhibits E-cadherin-mediated adherens junctions via binding to IQGAP1 in pancreatic carcinoma cells |
| Q42806256 | Rac1 and calmodulin interactions modulate dynamics of ARF6-dependent endocytosis. |
| Q40885218 | Rac1 gets fattier |
| Q38839225 | Rac1 in human diseases: The therapeutic potential of targeting Rac1 signaling regulatory mechanisms |
| Q30538902 | Rac1 recruitment to the archipelago structure of the focal adhesion through the fluid membrane as revealed by single-molecule analysis |
| Q30156899 | Rac1 recruits the adapter protein CMS/CD2AP to cell-cell contacts |
| Q24294337 | Rac1-induced cell migration requires membrane recruitment of the nuclear oncogene SET |
| Q38334837 | Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation |
| Q40455048 | Rac2 Functions in Both Neutrophils and Macrophages To Mediate Motility and Host Defense in Larval Zebrafish. |
| Q44548810 | Rac2 specificity in macrophage integrin signaling: potential role for Syk kinase |
| Q38362182 | Rac2, a hematopoiesis-specific Rho GTPase, specifically regulates mast cell protease gene expression in bone marrow-derived mast cells |
| Q45345797 | Raf and akt mediate distinct aspects of sensory axon growth |
| Q92825933 | Ran promotes membrane targeting and stabilization of RhoA to orchestrate ovarian cancer cell invasion |
| Q36322667 | Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors |
| Q36322227 | Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion. |
| Q36484404 | Rapidly relocating molecules between organelles to manipulate small GTPase activity |
| Q39221500 | Ras GTPases' interaction with effector domains: Breaking the families' barrier |
| Q49921459 | Ras and the Plasma Membrane: A Complicated Relationship. |
| Q35089365 | Ras pathway signaling on endomembranes |
| Q50102683 | Rce1: mechanism and inhibition. |
| Q28579464 | Real-time cross-correlation image analysis of early events in IgE receptor signaling |
| Q28576605 | Regulated exocytosis in neuroendocrine cells: a role for subplasmalemmal Cdc42/N-WASP-induced actin filaments |
| Q38865226 | Regulating Rho GTPases and their regulators |
| Q30494392 | Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1 |
| Q28577831 | Regulation of RhoA signaling by the cAMP-dependent phosphorylation of RhoGDIα |
| Q37395997 | Regulation of RhoGEF proteins by G12/13-coupled receptors |
| Q28293683 | Regulation of cystic fibrosis transmembrane regulator trafficking and protein expression by a Rho family small GTPase TC10 |
| Q81739907 | Regulation of membrane trafficking, cytoskeleton dynamics, and cell polarity by ROP/RAC GTPases |
| Q35005870 | Regulation of microtubule-organizing center orientation and actomyosin cytoskeleton rearrangement during immune interactions |
| Q34764253 | Reorganization of actin cytoskeleton by the phosphoinositide metabolite glycerophosphoinositol 4-phosphate |
| Q42326441 | Rescue of glandular dysmorphogenesis in PTEN-deficient colorectal cancer epithelium by PPARγ-targeted therapy. |
| Q42434602 | Rho Family GTPase modification and dependence on CAAX motif-signaled posttranslational modification |
| Q24658329 | Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. |
| Q38284409 | Rho GTPase isoforms in cell motility: Don't fret, we have FRET. |
| Q39861745 | Rho GTPase signaling and PTH 3-34, but not PTH 1-34, maintain the actin cytoskeleton and antagonize bisphosphonate effects in mouse osteoblastic MC3T3-E1 cells. |
| Q26865752 | Rho GTPases, phosphoinositides, and actin: a tripartite framework for efficient vesicular trafficking |
| Q28645748 | Rho and Rac take center stage |
| Q28505019 | Rho localization in cells and tissues |
| Q37933751 | Rho protein crosstalk: another social network? |
| Q33946486 | Rho proteins: linking signaling with membrane trafficking |
| Q46900605 | Rho signaling in Entamoeba histolytica modulates actomyosin-dependent activities stimulated during invasive behavior |
| Q37401139 | Rho signaling mediates cytoskeletal re-arrangements in octopus photoreceptors |
| Q41184119 | Rho small GTPase regulates the stability of individual focal adhesions: a FRET-based visualization of GDP/GTP exchange on small GTPases |
| Q38193984 | Rho, nuclear actin, and actin-binding proteins in the regulation of transcription and gene expression. |
| Q59052275 | Rho-GTPase Signalling in the Pathogenesis of Nephrotic Syndrome |
| Q35681634 | Rho-regulatory proteins in breast cancer cell motility and invasion |
| Q42735517 | Rho2 palmitoylation is required for plasma membrane localization and proper signaling to the fission yeast cell integrity mitogen- activated protein kinase pathway |
| Q40114788 | RhoA biological activity is dependent on prenylation but independent of specific isoprenoid modification. |
| Q36237156 | RhoA enhances store-operated Ca2+ entry and intestinal epithelial restitution by interacting with TRPC1 after wounding |
| Q28206364 | RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability |
| Q42437014 | RhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIalpha |
| Q37279963 | RhoB Mediates Phosphoantigen Recognition by Vγ9Vδ2 T Cell Receptor |
| Q34596684 | RhoB and the mammalian Diaphanous-related formin mDia2 in endosome trafficking |
| Q28512962 | RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development |
| Q35238124 | RhoB deficiency in thymic medullary epithelium leads to early thymic atrophy |
| Q34361919 | RhoB differentially controls Akt function in tumor cells and stromal endothelial cells during breast tumorigenesis |
| Q36185784 | RhoB is a component of the human cytomegalovirus assembly complex and is required for efficient viral production. |
| Q28589451 | RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells |
| Q37398071 | RhoB plays an essential role in CXCR2 sorting decisions |
| Q30516438 | RhoB regulates cell migration through altered focal adhesion dynamics |
| Q28215387 | RhoGDI-3 regulates RhoG and targets this protein to the Golgi complex through its unique N-terminal domain |
| Q35029243 | RhoGDI: A rheostat for the Rho switch. |
| Q24534900 | RhoGDI: multiple functions in the regulation of Rho family GTPase activities |
| Q38274663 | RhoGDIα-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis |
| Q36506021 | Role of competition between polarity sites in establishing a unique front |
| Q28262533 | Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion |
| Q98513562 | SLIT2/ROBO1-signaling inhibits macropinocytosis by opposing cortical cytoskeletal remodeling |
| Q55239712 | STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap. |
| Q35221640 | SWAN-1, a Caenorhabditis elegans WD repeat protein of the AN11 family, is a negative regulator of Rac GTPase function |
| Q33662304 | Sequestering of Rac by the Yersinia effector YopO blocks Fcgamma receptor-mediated phagocytosis |
| Q34412353 | Serine-71 phosphorylation of Rac1 modulates downstream signaling |
| Q37176427 | Silencing of D4-GDI inhibits growth and invasive behavior in MDA-MB-231 cells by activation of Rac-dependent p38 and JNK signaling |
| Q24811818 | Simultaneous imaging of GFP, CFP and collagen in tumors in vivo using multiphoton microscopy |
| Q30619317 | Single-molecule tracking of small GTPase Rac1 uncovers spatial regulation of membrane translocation and mechanism for polarized signaling |
| Q40304842 | Small rho GTPases and cholesterol biosynthetic pathway intermediates in African swine fever virus infection. |
| Q35071247 | Solo/Trio8, a membrane-associated short isoform of Trio, modulates endosome dynamics and neurite elongation |
| Q40727776 | Somatostatin, acting at receptor subtype 1, inhibits Rho activity, the assembly of actin stress fibers, and cell migration. |
| Q41662053 | Spatial analysis of Cdc42 activity reveals a role for plasma membrane-associated Cdc42 in centrosome regulation |
| Q34787970 | Spatial and temporal control of Rho GTPase functions |
| Q36576725 | Spatial segregation of Ras signaling: new evidence from fission yeast |
| Q44626769 | Spatio-temporal regulation of Rac1 and Cdc42 activity during nerve growth factor-induced neurite outgrowth in PC12 cells |
| Q27317056 | Spatiotemporal analysis of RhoA/B/C activation in primary human endothelial cells |
| Q83324479 | Spatiotemporal organization of Ras signaling: rasosomes and the galectin switch |
| Q40068834 | Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases. |
| Q35594487 | Spontaneous Cdc42 polarization independent of GDI-mediated extraction and actin-based trafficking |
| Q26745863 | Structural Mechanisms and Drug Discovery Prospects of Rho GTPases |
| Q53373409 | T-cadherin is located in the nucleus and centrosomes in endothelial cells. |
| Q37333868 | TROY interacts with Rho guanine nucleotide dissociation inhibitor α (RhoGDIα) to mediate Nogo-induced inhibition of neurite outgrowth |
| Q24305342 | Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix |
| Q36677555 | Targeting and localized signalling by small GTPases |
| Q24606819 | The 'invisible hand': regulation of RHO GTPases by RHOGDIs |
| Q52589292 | The Atypical Rho GTPase CHW-1 Works with SAX-3/Robo To Mediate Axon Guidance in Caenorhabditis elegans. |
| Q30164617 | The C-terminal domain of Rac1 contains two motifs that control targeting and signaling specificity |
| Q28472131 | The C-terminal sequence of RhoB directs protein degradation through an endo-lysosomal pathway |
| Q48191911 | The Cullin-3-Rbx1-KCTD10 complex controls endothelial barrier function via K63 ubiquitination of RhoB. |
| Q24607678 | The GTP/GDP cycling of rho GTPase TCL is an essential regulator of the early endocytic pathway |
| Q35576781 | The Mevalonate Synthesis Pathway as a Therapeutic Target in Cancer |
| Q26864271 | The Rac1 hypervariable region in targeting and signaling: a tail of many stories |
| Q38915601 | The Rho GTPase RhoB regulates cadherin expression and epithelial cell-cell interaction |
| Q40224658 | The activation of TC10, a Rho small GTPase, contributes to v-Rel-mediated transformation |
| Q42103022 | The anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration |
| Q48225911 | The catalytic domains of Clostridium sordellii lethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid. |
| Q24295264 | The complex of Arl2-GTP and PDE delta: from structure to function |
| Q35096291 | The dual effect of Rac2 on phospholipase D2 regulation that explains both the onset and termination of chemotaxis |
| Q24540862 | The exocytotic trafficking of TC10 occurs through both classical and nonclassical secretory transport pathways in 3T3L1 adipocytes |
| Q30455699 | The faces and friends of RhoGDI2. |
| Q28202993 | The lamellipodium: where motility begins |
| Q37056969 | The mechanisms and significance of up-regulation of RhoB expression by hypoxia and glucocorticoid in rat lung and A549 cells |
| Q37856526 | The mechanisms underlying the spatial spreading of signaling activity |
| Q41892751 | The perplexing case of the geranylgeranyl transferase-deficient mouse |
| Q36501163 | The physiology of membrane transport and endomembrane-based signalling |
| Q41441562 | The polybasic region of Rac1 modulates bacterial uptake independently of self-association and membrane targeting |
| Q35566863 | The polybasic region of Ras and Rho family small GTPases: a regulator of protein interactions and membrane association and a site of nuclear localization signal sequences |
| Q37958935 | The role of RhoJ in endothelial cell biology and angiogenesis. |
| Q33255052 | The role of geranylgeranylated proteins in human mesangial cell proliferation |
| Q38011133 | The role of small GTPases in neuronal morphogenesis and polarity |
| Q24292063 | The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreading |
| Q52549888 | The small GTPase Rho4 is involved in controlling cell morphology and septation in fission yeast. |
| Q40317960 | The use of GFP to localize Rho GTPases in living cells |
| Q34742771 | Therapeutic levels of the hydroxmethylglutaryl-coenzyme A reductase inhibitor lovastatin activate ras signaling via phospholipase D2. |
| Q24305656 | Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1 |
| Q39960021 | Transcriptional activation by the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen is facilitated by an N-terminal chromatin-binding motif. |
| Q44467311 | Transformation-selective apoptotic program triggered by farnesyltransferase inhibitors requires Bin1. |
| Q40169273 | Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility |
| Q40631985 | Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling |
| Q28290396 | Uncoupling of inhibitory and shuttling functions of rho GDP dissociation inhibitors |
| Q42800706 | Using inhibitors of prenylation to block localization and transforming activity |
| Q37180578 | VPS35 binds farnesylated N-Ras in the cytosol to regulate N-Ras trafficking |
| Q37690366 | Variability in statin-induced changes in gene expression profiles of pancreatic cancer. |
| Q36538171 | Wave-pinning and cell polarity from a bistable reaction-diffusion system |
| Q38719156 | Where no Ras has gone before: VPS35 steers N-Ras through the cytosol. |
| Q34962925 | X-linked inhibitor of apoptosis protein (XIAP) mediates cancer cell motility via Rho GDP dissociation inhibitor (RhoGDI)-dependent regulation of the cytoskeleton |
| Q28200973 | XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC |
| Q27932582 | Yeast translation elongation factor-1A binds vacuole-localized Rho1p to facilitate membrane integrity through F-actin remodeling |
| Q24811985 | Yersinia pseudotuberculosis spatially controls activation and misregulation of host cell Rac1. |
| Q37410311 | Yersinia pseudotuberculosis virulence determinants invasin, YopE, and YopT modulate RhoG activity and localization |
| Q47601469 | cAMP-induced activation of protein kinase A and p190B RhoGAP mediates down-regulation of TC10 activity at the plasma membrane and neurite outgrowth |
| Q36111209 | p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification |
| Q40239203 | p120 serine and threonine phosphorylation is controlled by multiple ligand-receptor pathways but not cadherin ligation |
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