Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells.

scientific article

Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.1501655
P932PMC publication ID4821714
P698PubMed publication ID26951800

P50authorDianne CoxQ88852359
Louis HodgsonQ37838987
P2093author name stringDianne Cox
Veronika Miskolci
Bin Wu
Yasmin Moshfegh
P2860cites workLocalized Rac activation dynamics visualized in living cellsQ24290403
Activation of endogenous Cdc42 visualized in living cellsQ24303606
Human neutrophils coordinate chemotaxis by differential activation of Rac1 and Rac2Q24316954
rac, a novel ras-related family of proteins that are botulinum toxin substratesQ24339158
Evolution of the Rho family of ras-like GTPases in eukaryotesQ24646801
Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI bindingQ24674800
A RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cellsQ27302353
A new genetically encoded single-chain biosensor for Cdc42 based on FRET, useful for live-cell imagingQ27334658
Rho GTPases: biochemistry and biologyQ27860645
Rho GTPases in cell biologyQ27860969
Formyl peptide receptors: a promiscuous subfamily of G protein-coupled receptors controlling immune responsesQ28272258
The TRQQKRP motif located near the C-terminus of Rac2 is essential for Rac2 biologic functions and intracellular localizationQ28513723
Spatial regulation of RhoC activity defines protrusion formation in migrating cellsQ28771327
Expression and translocation of Rac2 in eosinophils during superoxide generationQ47902437
Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migrationQ48009008
An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability.Q54226572
Rac1 and Rac2 regulate macrophage morphology but are not essential for migrationQ57909959
Rac1 and Rac2 control distinct events during antigen-stimulated mast cell exocytosisQ61919354
Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of oxidase componentsQ70500542
Rational design of genetically encoded fluorescence resonance energy transfer-based sensors of cellular Cdc42 signalingQ73226975
Mammalian Rho GTPases: new insights into their functions from in vivo studiesQ29615191
Coordination of Rho GTPase activities during cell protrusionQ29618432
Spatiotemporal dynamics of RhoA activity in migrating cellsQ29618433
Syk regulates multiple signaling pathways leading to CX3CL1 chemotaxis in macrophagesQ30427232
Sequential signaling in plasma-membrane domains during macropinosome formation in macrophagesQ30489942
SCAR knockouts in Dictyostelium: WASP assumes SCAR's position and upstream regulators in pseudopodsQ30528926
A Trio-Rac1-Pak1 signalling axis drives invadopodia disassemblyQ30582998
Synonymous modification results in high-fidelity gene expression of repetitive protein and nucleotide sequences.Q30641189
Expanded dynamic range of fluorescent indicators for Ca(2+) by circularly permuted yellow fluorescent proteins.Q30769723
Systematic comparison of constitutive promoters and the doxycycline-inducible promoterQ33582194
Spatial and temporal analysis of Rac activation during live neutrophil chemotaxisQ34164011
Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cellsQ34324446
The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activityQ35641633
Regulation of innate immunity by Rho GTPasesQ36064211
Rac1 and Rac2 differentially regulate actin free barbed end formation downstream of the fMLP receptorQ36119571
Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytesQ36380848
Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis.Q37031442
Cdc42 regulates Fc gamma receptor-mediated phagocytosis through the activation and phosphorylation of Wiskott-Aldrich syndrome protein (WASP) and neural-WASP.Q37406742
Spatio-temporal Rho GTPase signaling - where are we now?Q37756431
Rac GTPases in human diseasesQ37823072
Neutrophil migration: moving from zebrafish models to human autoimmunity.Q38151856
Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: outsourcing a key taskQ38193605
Rho GTPase isoforms in cell motility: Don't fret, we have FRET.Q38284409
Live cell imaging of RhoGTPase biosensors in tumor cellsQ39123670
Multiplex imaging of Rho family GTPase activities in living cellsQ39896662
Design and optimization of genetically encoded fluorescent biosensors: GTPase biosensorsQ40031657
Syk is required for monocyte/macrophage chemotaxis to CX3CL1 (Fractalkine).Q40376302
Rac1 deletion in mouse neutrophils has selective effects on neutrophil functions.Q40646102
Biosensors for characterizing the dynamics of rho family GTPases in living cellsQ41177591
Quantitative ratiometric imaging of FRET-biosensors in living cellsQ41915475
A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodiaQ42721724
Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functionsQ44187662
Human monocytes use Rac1, not Rac2, in the NADPH oxidase complexQ44545624
Rac2 is critical for neutrophil primary granule exocytosis.Q44836515
Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils.Q44915718
Comparison of the EF-1 alpha and the CMV promoter for engineering stable tumor cell lines using recombinant adeno-associated virus.Q45047434
Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain.Q45124244
Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particlesQ45140639
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)3479-3493
P577publication date2016-03-07
P1433published inJournal of ImmunologyQ3521441
P1476titleOptical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells
P478volume196

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cites work (P2860)
Q64978294Characterization of Genetically Encoded FRET Biosensors for Rho-Family GTPases.
Q33914878Controllable Photodynamic Therapy Implemented by Regulating Singlet Oxygen Efficiency
Q88447482Direct multiplex imaging and optogenetics of Rho GTPases enabled by near-infrared FRET
Q58560795Kalirin/Trio Rho GDP/GTP exchange factors regulate proinsulin and insulin secretion
Q90640438Macrophage polarization impacts tunneling nanotube formation and intercellular organelle trafficking
Q47807249Platelet-derived growth factor receptor-α and Ras-related C3 botulinum toxin substrate-1 regulate mechano-responsiveness of lung fibroblasts
Q47614425Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation.
Q41448310The Role of Rho-GTPases and actin polymerization during Macrophage Tunneling Nanotube Biogenesis

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