| scholarly article | Q13442814 |
| P50 | author | Martin A Schwartz | Q57237220 |
| P2093 | author name string | G M Bokoch | |
| C Chamberlain | |||
| K M Hahn | |||
| V S Kraynov | |||
| S Slabaugh | |||
| P433 | issue | 5490 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | visualization | Q451553 |
| P304 | page(s) | 333-337 | |
| P577 | publication date | 2000-10-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Localized Rac activation dynamics visualized in living cells | |
| P478 | volume | 290 |
| Q38275107 | A High-Content Assay for Biosensor Validation and for Examining Stimuli that Affect Biosensor Activity |
| Q36320639 | A Rac switch regulates random versus directionally persistent cell migration |
| Q44873778 | A Reaction-Diffusion Model Explains Amplification of the PLC/PKC Pathway in Fibroblast Chemotaxis |
| Q27302353 | A RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cells |
| Q30582998 | A Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly |
| Q30502428 | A biosensor generated via high-throughput screening quantifies cell edge Src dynamics |
| Q44951361 | A conserved sequence in caveolin-1 is both necessary and sufficient for caveolin polarity and cell directional migration |
| Q43042764 | A deuterohemin peptide extends lifespan and increases stress resistance in Caenorhabditis elegans |
| Q47072857 | A dominant negative form of Rac1 affects myogenesis of adult thoracic muscles in Drosophila |
| Q24649098 | A genetically encoded photoactivatable Rac controls the motility of living cells |
| Q29040265 | A growing family of guanine nucleotide exchange factors is responsible for activation of ras-family GTPases |
| Q24603357 | A landscape of driver mutations in melanoma |
| Q24307819 | A novel FERM domain including guanine nucleotide exchange factor is involved in Rac signaling and regulates neurite remodeling |
| Q36917600 | A novel pathway spatiotemporally activates Rac1 and redox signaling in response to fluid shear stress |
| Q42828083 | A pair of fluorescent resonance energy transfer-based probes for tyrosine phosphorylation of the CrkII adaptor protein in vivo. |
| Q24329072 | ARHGAP18, a GTPase-activating protein for RhoA, controls cell shape, spreading, and motility |
| Q35607004 | ASYMPTOTIC AND BIFURCATION ANALYSIS OF WAVE-PINNING IN A REACTION-DIFFUSION MODEL FOR CELL POLARIZATION. |
| Q27342486 | Acetylation of the RhoA GEF Net1A controls its subcellular localization and activity |
| Q46568535 | Actin depolymerization mediated loss of SNTA1 phosphorylation and Rac1 activity has implications on ROS production, cell migration and apoptosis. |
| Q57369567 | Actin filament uncapping localizes to ruffling lamellae and rocketing vesicles |
| Q35017730 | Actin, microtubules and focal adhesion dynamics during cell migration |
| Q40525953 | Activation of Rac1 by paxillin-Crk-DOCK180 signaling complex is antagonized by Rap1 in migrating NBT-II cells |
| Q30453215 | Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression. |
| Q34324446 | Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells |
| Q33638097 | Activation of the WAVE complex by coincident signals controls actin assembly |
| Q36619468 | Activity of PLCε contributes to chemotaxis of fibroblasts towards PDGF |
| Q36323206 | Activity of Rho-family GTPases during cell division as visualized with FRET-based probes |
| Q51421201 | Actomyosin contractility and RhoGTPases affect cell-polarity and directional migration during haptotaxis. |
| Q30309202 | Adhesion assembly, disassembly and turnover in migrating cells -- over and over and over again |
| Q27345282 | African swine fever virus uses macropinocytosis to enter host cells |
| Q33689631 | Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling |
| Q30657697 | An ELMO2-RhoG-ILK network modulates microtubule dynamics. |
| Q27334396 | An actin-based wave generator organizes cell motility |
| Q40615070 | An activating mutant of Rac1 that fails to interact with Rho GDP-dissociation inhibitor stimulates membrane ruffling in mammalian cells |
| Q45118374 | An alpha4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells |
| Q36909813 | Analysis of integrin signaling by fluorescence resonance energy transfer |
| Q53213474 | Analysis of nucleo-cytoplasmic shuttling of the proto-oncogene SET/I2PP2A. |
| Q50739786 | Analysis of the spatiotemporal activation of rho GTPases using Raichu probes. |
| Q51787550 | Antagonistic activities of Rho and Rac GTPases underlie the transition from neural crest delamination to migration. |
| Q81931164 | Approaches for studying angiogenesis-related signal transduction |
| Q34360604 | Assembly and mechanosensory function of focal contacts |
| Q36686091 | Big roles for small GTPases in the control of directed cell movement |
| Q42412250 | Biosensor Förster resonance energy transfer detection by the phasor approach to fluorescence lifetime imaging microscopy |
| Q41177591 | Biosensors for characterizing the dynamics of rho family GTPases in living cells |
| Q42823920 | Biosensors of DsRed as FRET Partner with CFP or GFP for Quantitatively Imaging Induced Activation of Rac, Cdc42 in Living Cells |
| Q24658017 | Bves directly interacts with GEFT, and controls cell shape and movement through regulation of Rac1/Cdc42 activity |
| Q37242270 | CED-10/Rac1 mediates axon guidance by regulating the asymmetric distribution of MIG-10/lamellipodin. |
| Q37069224 | CPK3-phosphorylated RhoGDI1 is essential in the development of Arabidopsis seedlings and leaf epidermal cells |
| Q30717233 | Calculation of forces at focal adhesions from elastic substrate data: the effect of localized force and the need for regularization |
| Q24336049 | Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis |
| Q37427560 | Cdc42 and the actin-related protein/neural Wiskott-Aldrich syndrome protein network mediate cellular invasion by Cryptosporidium parvum |
| Q37031442 | Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis. |
| Q35607422 | Cell adhesion molecules during inner ear and hair cell development, including notch and its ligands |
| Q29616711 | Cell migration: Rho GTPases lead the way |
| Q33185799 | Characterization of one- and two-photon excitation fluorescence resonance energy transfer microscopy |
| Q37941791 | Chemical tools for studying directed cell migration. |
| Q28203266 | Chimaerins, novel non-protein kinase C phorbol ester receptors, associate with Tmp21-I (p23): evidence for a novel anchoring mechanism involving the chimaerin C1 domain |
| Q30539004 | Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor. |
| Q92893100 | Combining FRET and optical tweezers to study RhoGTPases spatio-temporal dynamics upon local stimulation |
| Q37612496 | Combining mechanical and optical approaches to dissect cellular mechanobiology |
| Q37322476 | Compartmentalization of redox signaling through NADPH oxidase-derived ROS. |
| Q27312648 | Competition for actin between two distinct F-actin networks defines a bistable switch for cell polarization. |
| Q33211372 | Concentric zones of active RhoA and Cdc42 around single cell wounds |
| Q36058096 | Conservation of boundary extension mechanisms between plants and animals |
| Q29615212 | Conserved microtubule-actin interactions in cell movement and morphogenesis |
| Q44356627 | Control of the G-protein cascade dynamics by GDP dissociation inhibitors |
| Q37058907 | Cooperative activation of PI3K by Ras and Rho family small GTPases |
| Q35927687 | Coordinating cytoskeletal tracks to polarize cellular movements |
| Q29618432 | Coordination of Rho GTPase activities during cell protrusion |
| Q30488818 | Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases. |
| Q30500307 | Deletion of ABCA1 and ABCG1 impairs macrophage migration because of increased Rac1 signaling |
| Q35042854 | Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network |
| Q40031657 | Design and optimization of genetically encoded fluorescent biosensors: GTPase biosensors |
| Q30484062 | Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors. |
| Q38226851 | Directed migration of mesenchymal cells: where signaling and the cytoskeleton meet |
| Q36322203 | Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts. |
| Q44530451 | Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils |
| Q28187402 | Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration |
| Q28267493 | Dock4 is regulated by RhoG and promotes Rac-dependent cell migration |
| Q34415160 | Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP-76 and Vav1. |
| Q37823095 | Dynamics of the Rho-family small GTPases in actin regulation and motility |
| Q43823908 | E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contacts |
| Q37445712 | EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180. |
| Q28568393 | Effects of cell tension on the small GTPase Rac |
| Q64935328 | Emerging Roles of the Endoplasmic Reticulum Associated Unfolded Protein Response in Cancer Cell Migration and Invasion. |
| Q31101294 | Epi-fluorescence microscopy |
| Q38348001 | Epithelial morphogenesis: the mouse eye as a model system |
| Q26771793 | Epithelial-Mesenchymal Transitions during Neural Crest and Somite Development |
| Q27305030 | Excess centrosomes perturb dynamic endothelial cell repolarization during blood vessel formation |
| Q41953919 | Experimental and DFT studies: novel structural modifications greatly enhance the solvent sensitivity of live cell imaging dyes |
| Q38116802 | Extensive use of FRET in biological imaging |
| Q30620668 | F-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling |
| Q29616029 | FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly |
| Q40460117 | FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts. |
| Q37657120 | FRET and mechanobiology |
| Q60045748 | FRET biosensor allows spatio-temporal observation of shear stress-induced polar RhoGDIα activation |
| Q30425496 | FRET microscopy in 2010: the legacy of Theodor Förster on the 100th anniversary of his birth |
| Q47745661 | FRET monitoring of a nonribosomal peptide synthetase |
| Q41888356 | Feedback mechanism for microtubule length regulation by stathmin gradients. |
| Q36236775 | Fibroblasts Lead the Way: A Unified View of 3D Cell Motility |
| Q38114125 | FilGAP and its close relatives: a mediator of Rho-Rac antagonism that regulates cell morphology and migration |
| Q41882915 | Fluctuation-based imaging of nuclear Rac1 activation by protein oligomerisation |
| Q36347888 | Fluorescence (Förster) resonance energy transfer imaging of oncogene activity in living cells |
| Q35057325 | Fluorescence imaging of signaling networks. |
| Q24673219 | Fluorescence resonance energy transfer (FRET) microscopy imaging of live cell protein localizations |
| Q30309399 | Fluorescence resonance energy transfer biosensors that detect Ran conformational changes and a Ran x GDP-importin-beta -RanBP1 complex in vitro and in intact cells |
| Q34179589 | Fluorescence resonance energy transfer-based stoichiometry in living cells |
| Q41762527 | Forced unfolding of proteins within cells |
| Q80037379 | Front and back by Rho and Rac |
| Q33245683 | Functional proteometrics for cell migration. |
| Q38236253 | Förster resonance energy transfer - an approach to visualize the spatiotemporal regulation of macromolecular complex formation and compartmentalized cell signaling |
| Q30410957 | Förster resonance energy transfer microscopy and spectroscopy for localizing protein-protein interactions in living cells |
| Q37148892 | G protein α12 (Gα12) is a negative regulator of kidney injury molecule-1-mediated efferocytosis |
| Q39181519 | GDNF and endothelin 3 regulate migration of enteric neural crest-derived cells via protein kinase A and Rac1. |
| Q38627141 | GEF-H1: orchestrating the interplay between cytoskeleton and vesicle trafficking |
| Q37040651 | GEFs and Rac GTPases control directional specificity of neurite extension along the anterior-posterior axis |
| Q42809898 | GSK-3β is essential for physiological electric field-directed Golgi polarization and optimal electrotaxis |
| Q24555054 | Galpha i3 binding to calnuc on Golgi membranes in living cells monitored by fluorescence resonance energy transfer of green fluorescent protein fusion proteins |
| Q27939151 | Gbetagamma recruits Rho1 to the site of polarized growth during mating in budding yeast |
| Q90494776 | Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks |
| Q41173866 | Genetically Encoded Photoactuators and Photosensors for Characterization and Manipulation of Pluripotent Stem Cells |
| Q35070429 | Geometry sensing through POR1 regulates Rac1 activity controlling early osteoblast differentiation in response to nanofiber diameter |
| Q36502957 | Ghrelin and the growth hormone secretagogue receptor constitute a novel autocrine pathway in astrocytoma motility |
| Q43655807 | Glowing switches |
| Q28594017 | Governing epidermal homeostasis by coupling cell-cell adhesion to integrin and growth factor signaling, proliferation, and apoptosis |
| Q37439970 | Green light to illuminate signal transduction events. |
| Q47070762 | Growth cone pathfinding and filopodial dynamics are mediated separately by Cdc42 activation. |
| Q50439892 | Guanidinium-pendant oligofluorene for rapid and specific identification of antibiotics with membrane-disrupting ability. |
| Q30490189 | Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edge |
| Q92008102 | HACE1 deficiency leads to structural and functional neurodevelopmental defects |
| Q39496498 | HAb18G/CD147 promotes cell motility by regulating annexin II-activated RhoA and Rac1 signaling pathways in hepatocellular carcinoma cells |
| Q30155981 | HBx expression activates RhoA GTPase: impact on cell migration |
| Q30479101 | Helicobacter pylori CagA induces AGS cell elongation through a cell retraction defect that is independent of Cdc42, Rac1, and Arp2/3. |
| Q27329542 | High glucose-mediated oxidative stress impairs cell migration |
| Q27350493 | Human Mena associates with Rac1 small GTPase in glioblastoma cell lines |
| Q50295767 | Identification of a Fragmented Small GTPase Capable of Conditional Effector Binding. |
| Q30157925 | Identification of a bipartite focal adhesion localization signal in RhoU/Wrch-1, a Rho family GTPase that regulates cell adhesion and migration |
| Q42467995 | Identification of focal adhesion kinase (FAK) and phosphatidylinositol 3-kinase (PI3-kinase) as Par3 partners by proteomic analysis |
| Q30311873 | Illuminating adhesion complexes in migrating cells: moving toward a bright future |
| Q50777867 | Imaging activation of two Ras isoforms simultaneously in a single cell. |
| Q34228151 | Imaging biochemistry inside cells |
| Q51504985 | Imaging protein activity in live embryos using fluorescence resonance energy transfer biosensors. |
| Q37173653 | Imaging the coordination of multiple signalling activities in living cells |
| Q90013136 | In vivo monitoring of plant small GTPase activation using a Förster resonance energy transfer biosensor |
| Q37980724 | Inhibition and termination of physiological responses by GTPase activating proteins |
| Q36877323 | Integrin modulation and signaling in leukocyte adhesion and migration |
| Q34858243 | Integrin signaling: it's where the action is. |
| Q30422511 | Integrin α6β4 cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation |
| Q30417364 | Integrins in cell migration |
| Q30437361 | Integrins in cell migration--the actin connection |
| Q24292355 | Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI |
| Q30439149 | Intensity range based quantitative FRET data analysis to localize protein molecules in live cell nuclei |
| Q34180955 | Internet-based image analysis quantifies contractile behavior of individual fibroblasts inside model tissue |
| Q30637840 | Interplay between chemotaxis and contact inhibition of locomotion determines exploratory cell migration |
| Q33573230 | Interplay of PKA and Rac: fine-tuning of Rac localization and signaling |
| Q40724176 | Intracellular coupling of adhesion receptors: molecular proximity measurements |
| Q30845404 | Intracellular mechanics of migrating fibroblasts |
| Q89606197 | Intracellular signaling dynamics and their role in coordinating tissue repair |
| Q34634197 | Intramolecular interactions between the Dbl homology (DH) domain and the carboxyl-terminal region of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) act as an autoinhibitory mechanism for the regulation of MyoGEF functions |
| Q28592745 | Involvement of Beclin 1 in engulfment of apoptotic cells |
| Q28568401 | Involvement of a Rac activator,P-Rex1, in neurotrophin-derived signaling and neuronal migration |
| Q34483676 | Kiss-and-coat and compartment mixing: coupling exocytosis to signal generation and local actin assembly |
| Q34133895 | Knowledge-based design of a biosensor to quantify localized ERK activation in living cells |
| Q30843845 | Leader cells regulate collective cell migration via Rac activation in the downstream signaling of integrin β1 and PI3K. |
| Q34360589 | Leukocyte transendothelial migration: orchestrating the underlying molecular machinery |
| Q38510847 | Lighting Up the Force: Investigating Mechanisms of Mechanotransduction Using Fluorescent Tension Probes |
| Q37722078 | Live cell imaging of mechanotransduction |
| Q35926228 | Live-cell fluorescence microscopy with molecular biosensors: what are we really measuring? |
| Q34560883 | Live-cell fluorescent biosensors for activated signaling proteins |
| Q30476117 | Localized RhoA activation as a requirement for the induction of membrane ruffling |
| Q37160157 | Localized alpha4 integrin phosphorylation directs shear stress-induced endothelial cell alignment |
| Q46499640 | Localized cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress. |
| Q36574300 | Localizing NADPH oxidase-derived ROS. |
| Q30310722 | Mapping mechanical strain of an endogenous cytoskeletal network in living endothelial cells |
| Q46966283 | Matrix and meaning |
| Q38714305 | Measles Virus Enters Breast and Colon Cancer Cell Lines through a PVRL4-Mediated Macropinocytosis Pathway |
| Q36921736 | Mechanisms of gradient detection: a comparison of axon pathfinding with eukaryotic cell migration. |
| Q34074645 | Mechanisms of polarization of the shape of fibroblasts and epitheliocytes: Separation of the roles of microtubules and Rho-dependent actin-myosin contractility |
| Q30167694 | Mechanisms through which Sos-1 coordinates the activation of Ras and Rac. |
| Q44274595 | Membrane lipid organization is critical for human neutrophil polarization. |
| Q28189437 | Membrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signaling |
| Q34002994 | Mesenchymal migration as a therapeutic target in glioblastoma |
| Q34594627 | Microscope-based techniques to study cell adhesion and migration. |
| Q34719915 | Microtubule-actin cross-talk at focal adhesions |
| Q30602530 | Microtubules stabilize cell polarity by localizing rear signals. |
| Q36512122 | Millisecond spatiotemporal dynamics of FRET biosensors by the pair correlation function and the phasor approach to FLIM |
| Q37549801 | Mimicking transient activation of protein kinases in living cells. |
| Q28566981 | Modulation of Rac localization and function by dynamin |
| Q35681638 | Molecular basis for Rho GTPase signaling specificity |
| Q46365956 | Molecular mechanisms of anti-oxidant and anti-aging effects induced by convallatoxin in Caenorhabditis elegans |
| Q92409391 | Multifaceted Rho GTPase Signaling at the Endomembranes |
| Q38809211 | Multiple mechanisms of 3D migration: the origins of plasticity |
| Q35952748 | Multiple parallelisms in animal cytokinesis. |
| Q24548672 | Multiple sequence elements facilitate Chp Rho GTPase subcellular location, membrane association, and transforming activity |
| Q39896662 | Multiplex imaging of Rho family GTPase activities in living cells |
| Q40422606 | Muscle costameric protein, Chisel/Smpx, associates with focal adhesion complexes and modulates cell spreading in vitro via a Rac1/p38 pathway. |
| Q30430251 | Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front-back polarity in migrating cells |
| Q37216665 | Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC |
| Q30308768 | Nanosecond fluorescence resonance energy transfer-fluorescence lifetime imaging microscopy to localize the protein interactions in a single living cell |
| Q33289525 | Neurite outgrowth on a fibronectin isoform expressed during peripheral nerve regeneration is mediated by the interaction of paxillin with alpha4beta1 integrins |
| Q34574438 | Neutrophil polarization: spatiotemporal dynamics of RhoA activity support a self-organizing mechanism |
| Q27319061 | Niche-associated activation of rac promotes the asymmetric division of Drosophila female germline stem cells |
| Q30524670 | Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1 |
| Q100633469 | Non-junctional role of Cadherin3 in cell migration and contact inhibition of locomotion via domain-dependent, opposing regulation of Rac1 |
| Q35925311 | Nonpolarized signaling reveals two distinct modes of 3D cell migration |
| Q36506684 | Novel localization of formin mDia2: importin β-mediated delivery to and retention at the cytoplasmic side of the nuclear envelope |
| Q51839904 | Novel mechanism of the co-regulation of nuclear transport of SmgGDS and Rac1. |
| Q33649852 | Novel role of NADPH oxidase in angiogenesis and stem/progenitor cell function. |
| Q90451628 | Nε-Carboxymethyl-Lysine Negatively Regulates Foam Cell Migration via the Vav1/Rac1 Pathway |
| Q30738195 | Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells. |
| Q37985027 | Optogenetic reporters: Fluorescent protein-based genetically encoded indicators of signaling and metabolism in the brain |
| Q36881341 | Ovarian cancer G protein coupled receptor 1 suppresses cell migration of MCF7 breast cancer cells via a Gα12/13-Rho-Rac1 pathway |
| Q30524150 | Oxidized LDL/CD36 interaction induces loss of cell polarity and inhibits macrophage locomotion |
| Q27324467 | PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion |
| Q27312034 | PTP-PEST couples membrane protrusion and tail retraction via VAV2 and p190RhoGAP. |
| Q24314659 | Pak1 and PIX regulate contact inhibition during epithelial wound healing |
| Q35014178 | Patterning pallet arrays for cell selection based on high-resolution measurements of fluorescent biosensors |
| Q24337723 | Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics |
| Q28208448 | Phorbol esters and related analogs regulate the subcellular localization of beta 2-chimaerin, a non-protein kinase C phorbol ester receptor |
| Q34698020 | Phosphoinositide-3 kinase-Rac1-c-Jun NH2-terminal kinase signaling mediates collagen I-induced cell scattering and up-regulation of N-cadherin expression in mouse mammary epithelial cells |
| Q35606814 | Phosphoinositides and Rho proteins spatially regulate actin polymerization to initiate and maintain directed movement in a one-dimensional model of a motile cell |
| Q34187418 | Polarized fluorescence resonance energy transfer microscopy |
| Q34572179 | Positive and negative regulation of T-cell activation by adaptor proteins |
| Q60959651 | Post-Translational Modification and Subcellular Distribution of Rac1: An Update |
| Q51745981 | Postprandial triglyceride-rich lipoproteins promote invasion of human coronary artery smooth muscle cells in a fatty-acid manner through PI3k-Rac1-JNK signaling. |
| Q39885096 | Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN. |
| Q30484908 | Protein kinase A regulates 3-phosphatidylinositide dynamics during platelet-derived growth factor-induced membrane ruffling and chemotaxis |
| Q35788969 | Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor α. |
| Q36322119 | Proximal, selective, and dynamic interactions between integrin alphaIIbbeta3 and protein tyrosine kinases in living cells |
| Q35384848 | Pulse-shaping based two-photon FRET stoichiometry |
| Q36325811 | Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold |
| Q33384418 | Quantification of local morphodynamics and local GTPase activity by edge evolution tracking |
| Q37339847 | Quantitative analysis of protease recognition by inhibitors in plasma using microscale thermophoresis |
| Q52872492 | Quantitative imaging of Rac1 activity in Dictyostelium cells with a fluorescently labelled GTPase-binding domain from DPAKa kinase. |
| Q41915475 | Quantitative ratiometric imaging of FRET-biosensors in living cells |
| Q36545935 | Quinic acid could be a potential rejuvenating natural compound by improving survival of Caenorhabditis elegans under deleterious conditions |
| Q33564310 | R-Ras controls membrane protrusion and cell migration through the spatial regulation of Rac and Rho |
| Q92094136 | RAC1-Dependent ORAI1 Translocation to the Leading Edge Supports Lamellipodia Formation and Directional Persistence |
| Q30444197 | RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migration |
| Q36779662 | Rac GTPase instructs nuclear factor-kappaB activation by conveying the SCF complex and IkBalpha to the ruffling membranes |
| Q36322960 | Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis |
| Q35212986 | Rac regulates cardiovascular superoxide through diverse molecular interactions: more than a binary GTP switch |
| Q30481827 | Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division |
| Q42872034 | Rac1 activation in podocytes induces rapid foot process effacement and proteinuria |
| Q33742060 | Rac1 dynamics in the human opportunistic fungal pathogen Candida albicans |
| Q38839225 | Rac1 in human diseases: The therapeutic potential of targeting Rac1 signaling regulatory mechanisms |
| Q30476950 | Rac1 is essential for platelet lamellipodia formation and aggregate stability under flow. |
| Q37562941 | Rac1 mediates laminar shear stress-induced vascular endothelial cell migration |
| Q93153167 | Rac1-dependent phagocytosis of apoptotic cells by oral squamous cell carcinoma cells: A possible driving force for tumor progression |
| Q51733874 | Rac1/WAVE2 and Cdc42/N-WASP Participation in Actin-Dependent Host Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi. |
| Q29616686 | Random versus directionally persistent cell migration |
| Q30483788 | Rapid turnover rate of phosphoinositides at the front of migrating MDCK cells |
| Q34467828 | Ras GTPases: singing in tune |
| Q37135987 | Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy |
| Q34134974 | Real-time molecular and cellular analysis: the new frontier of drug discovery |
| Q38821204 | Recent developments of genetically encoded optical sensors for cell biology |
| Q36884063 | Reciprocal regulation of PKA and Rac signaling |
| Q30927533 | Recombinant Antibodies to the Small GTPase Rab6 as Conformation Sensors |
| Q24324823 | Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion |
| Q30310356 | Regulation of Rac1 activation by the low density lipoprotein receptor-related protein |
| Q30435862 | Regulation of actin cytoskeleton dynamics by Arf-family GTPases |
| Q34989008 | Regulation of breast cancer cell motility by T-cell lymphoma invasion and metastasis-inducing protein. |
| Q39935686 | Regulation of endogenous transmembrane receptors through optogenetic Cry2 clustering |
| Q40341780 | Regulation of epithelial tubule formation by Rho family GTPases |
| Q30441564 | Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase |
| Q34204472 | Regulation of leading edge microtubule and actin dynamics downstream of Rac1 |
| Q43906183 | Regulation of rho GTPases by crosstalk and neuronal activity in vivo. |
| Q30163832 | Regulation of the NADPH-oxidase complex of phagocytic leukocytes. Recent insights from structural biology, molecular genetics, and microscopy |
| Q36480536 | Regulation of the actin cytoskeleton by PIP2 in cytokinesis |
| Q38284409 | Rho GTPase isoforms in cell motility: Don't fret, we have FRET. |
| Q35127959 | Rho GTPases and the regulation of endothelial permeability |
| Q27860969 | Rho GTPases in cell biology |
| Q28647606 | Rho GTPases in growth cone guidance |
| Q29620432 | Rho GTPases in neuronal morphogenesis |
| Q37377346 | Rho GTPases orient directional sensing in chemotaxis |
| Q28645748 | Rho and Rac take center stage |
| Q38283635 | Rho family GTPases: making it to the third dimension |
| Q41184119 | Rho small GTPase regulates the stability of individual focal adhesions: a FRET-based visualization of GDP/GTP exchange on small GTPases |
| Q34457173 | Rho-family GTPases in cadherin-mediated cell-cell adhesion |
| Q30597529 | RhoA and membrane fluidity mediates the spatially polarized Src/FAK activation in response to shear stress. |
| Q37558943 | Role of SNTA1 in Rac1 activation, modulation of ROS generation, and migratory potential of human breast cancer cells |
| Q33733519 | Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration |
| Q35547373 | Roles of Rho-family GTPases in cell polarisation and directional migration |
| Q30527901 | SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility |
| Q42964178 | SIMULATING BIOCHEMICAL SIGNALING NETWORKS IN COMPLEX MOVING GEOMETRIES. |
| Q55239712 | STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap. |
| Q28586573 | SWAP-70 regulates c-kit-induced mast cell activation, cell-cell adhesion, and migration |
| Q41820658 | SWAP-70 regulates mast cell FcepsilonRI-mediated signaling and anaphylaxis |
| Q33885377 | Scaffold proteins IRSp53 and spinophilin regulate localized Rac activation by T-lymphocyte invasion and metastasis protein 1 (TIAM1). |
| Q56895078 | Selection and application of recombinant antibodies as sensors of rab protein conformation |
| Q36106835 | Selective amino acid restriction differentially affects the motility and directionality of DU145 and PC3 prostate cancer cells |
| Q37192032 | Selective labeling of proteins with chemical probes in living cells |
| Q85068837 | Sensing and controlling protein dynamics |
| Q39867658 | Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis. |
| Q42917027 | Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases |
| Q34648232 | Shedding light on cell signaling: interpretation of FRET biosensors |
| Q37935313 | Shining light on Drosophila oogenesis: live imaging of egg development. |
| Q30278918 | Signaling networks that regulate cell migration |
| Q44322255 | Simultaneous quantification of cell motility and protein-membrane-association using active contours. |
| Q38235814 | Single-cell imaging of mechanotransduction in endothelial cells |
| Q36528170 | Small GTPase protein Rac-1 is activated with maturation and regulates cell morphology and function in chondrocytes |
| Q34934273 | Small GTPases take the stage |
| Q34164011 | Spatial and temporal analysis of Rac activation during live neutrophil chemotaxis |
| Q40060648 | Spatial and temporal regulation of focal adhesion kinase activity in living cells. |
| Q30498093 | Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53 |
| Q30476244 | Spatial regulation of the cAMP-dependent protein kinase during chemotactic cell migration |
| Q36325064 | Spatial restriction of alpha4 integrin phosphorylation regulates lamellipodial stability and alpha4beta1-dependent cell migration |
| Q27342706 | Spatio-temporal co-ordination of RhoA, Rac1 and Cdc42 activation during prototypical edge protrusion and retraction dynamics |
| Q36015668 | Spatio-temporal regulation of Rac1 localization and lamellipodia dynamics during epithelial cell-cell adhesion |
| Q30482535 | Spatiotemporal activation of Rac1 for engulfment of apoptotic cells |
| Q92668118 | Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways |
| Q37514902 | Spatiotemporal imaging of small GTPases activity in live cells |
| Q36118494 | Specificity in reactive oxidant signaling: think globally, act locally |
| Q36852226 | Spontaneous nucleotide exchange in low molecular weight GTPases by fluorescently labeled gamma-phosphate-linked GTP analogs |
| Q51694511 | Stathmin mediates neuroblastoma metastasis in a tubulin-independent manner via RhoA/ROCK signaling and enhanced transendothelial migration. |
| Q24675182 | Synapse formation is regulated by the signaling adaptor GIT1 |
| Q45061800 | Syndecan-4 regulates ATF-2 transcriptional activity in a Rac1-dependent manner |
| Q30641189 | Synonymous modification results in high-fidelity gene expression of repetitive protein and nucleotide sequences. |
| Q30531107 | Synthetic spatially graded Rac activation drives cell polarization and movement |
| Q90591291 | Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions |
| Q36133978 | Targeted Proteomics-Driven Computational Modeling of Macrophage S1P Chemosensing |
| Q24305342 | Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix |
| Q28343581 | Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions |
| Q48561386 | Teaching resources. Imaging signal transduction in living cells with fluorescent proteins. |
| Q30441975 | The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL). |
| Q52375209 | The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics. |
| Q35212329 | The PI 3-kinase and mTOR signaling pathways are important modulators of epithelial tubule formation |
| Q37094426 | The PIX-GIT complex: a G protein signaling cassette in control of cell shape |
| Q38786537 | The Rac-FRET mouse reveals tight spatiotemporal control of Rac activity in primary cells and tissues |
| Q37387817 | The Rac-GAP Bcr is a novel regulator of the Par complex that controls cell polarity. |
| Q24670372 | The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src |
| Q90370141 | The adhesion and migration of microglia to β-amyloid (Aβ) is decreased with aging and inhibited by Nogo/NgR pathway |
| Q40108802 | The calcium-sensing receptor changes cell shape via a beta-arrestin-1 ARNO ARF6 ELMO protein network. |
| Q37863400 | The diverse roles of Rac signaling in tumorigenesis |
| Q36147572 | The dynamics of Rho GTPase signaling and implications for targeting cancer and the tumor microenvironment |
| Q26751231 | The dynamics of spatio-temporal Rho GTPase signaling: formation of signaling patterns |
| Q93204172 | The guanine nucleotide exchange factor Vav3 modulates oligodendrocyte precursor differentiation and supports remyelination in white matter lesions |
| Q30519429 | The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration |
| Q28202993 | The lamellipodium: where motility begins |
| Q38053051 | The many faces of the guanine-nucleotide exchange factor trio. |
| Q35566863 | The polybasic region of Ras and Rho family small GTPases: a regulator of protein interactions and membrane association and a site of nuclear localization signal sequences |
| Q36323790 | The relationship between force and focal complex development |
| Q34598154 | The role of Rho GTPases and associated kinases in regulating neurite outgrowth |
| Q38835757 | The role of integrins in glaucoma |
| Q97536434 | The role of single cell mechanical behavior and polarity in driving collective cell migration |
| Q30587438 | The three-way switch operation of Rac1/RhoA GTPase-based circuit controlling amoeboid-hybrid-mesenchymal transition |
| Q28217963 | The two hats of SOS |
| Q37705792 | The β-actin mRNA zipcode regulates epithelial adherens junction assembly but not maintenance. |
| Q34405311 | Three-chromophore FRET microscopy to analyze multiprotein interactions in living cells |
| Q30431100 | Three-color spectral FRET microscopy localizes three interacting proteins in living cells |
| Q36317205 | Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration |
| Q24305656 | Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1 |
| Q30480454 | To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front |
| Q39092250 | Tools for live imaging of active Rho GTPases in Xenopus |
| Q30667628 | Toward understanding RhoGTPase specificity: structure, function and local activation |
| Q24293175 | Type I PIPK-alpha regulates directed cell migration by modulating Rac1 plasma membrane targeting and activation |
| Q38057750 | Untangling the complexity of PAK1 dynamics: The future challenge |
| Q24515256 | VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam |
| Q30961526 | Vascular endothelial growth factor causes translocation of p47phox to membrane ruffles through WAVE1. |
| Q44644024 | Visualization of Rab5 activity in living cells by FRET microscopy and influence of plasma-membrane-targeted Rab5 on clathrin-dependent endocytosis |
| Q35893777 | Visualization of molecular activities inside living cells with fluorescent labels |
| Q41613895 | Visualization of the Activity of Rac1 Small GTPase in a Cell |
| Q35085294 | Visualization of the spatial and temporal dynamics of intracellular signaling |
| Q37202389 | Visualizing and quantifying adhesive signals |
| Q35263396 | Visualizing dynamic activities of signaling enzymes using genetically encodable FRET-based biosensors from designs to applications |
| Q47138233 | Visualizing the spatiotemporal map of Rac activation in bovine aortic endothelial cells under laminar and disturbed flows. |
| Q30167979 | Wasp recruitment to the T cell:APC contact site occurs independently of Cdc42 activation |
| Q34156498 | Watching proteins in the wild: fluorescence methods to study protein dynamics in living cells |
| Q30309253 | Why FRET about Ran? |
| Q24811985 | Yersinia pseudotuberculosis spatially controls activation and misregulation of host cell Rac1. |
| Q27321434 | bFGF Regulates PI3-Kinase-Rac1-JNK Pathway and Promotes Fibroblast Migration in Wound Healing |
| Q40415906 | c-Cbl regulates migration of v-Abl-transformed NIH 3T3 fibroblasts via Rac1. |
| Q33787261 | p23/Tmp21 differentially targets the Rac-GAP beta2-chimaerin and protein kinase C via their C1 domains |
| Q34120500 | p85α recruitment by the CD300f phosphatidylserine receptor mediates apoptotic cell clearance required for autoimmunity suppression |
| Q28551117 | siRNA Screen Identifies Trafficking Host Factors that Modulate Alphavirus Infection |
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