| scholarly article | Q13442814 |
| P356 | DOI | 10.1042/BJ20130290 |
| P698 | PubMed publication ID | 23763313 |
| P2093 | author name string | Fumihiko Nakamura | |
| P2860 | cites work | Rac and Rho GTPases in cancer cell motility control | Q21245504 |
| The small GTPase RalA targets filamin to induce filopodia | Q22008839 | ||
| Localized Rac activation dynamics visualized in living cells | Q24290403 | ||
| Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation | Q24297812 | ||
| FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling | Q24297925 | ||
| Rho‐kinase/ROCK: A key regulator of the cytoskeleton and cell polarity | Q24298069 | ||
| Activation of endogenous Cdc42 visualized in living cells | Q24303606 | ||
| DOCK10-mediated Cdc42 activation is necessary for amoeboid invasion of melanoma cells | Q24319212 | ||
| A vascular cell-restricted RhoGAP, p73RhoGAP, is a key regulator of angiogenesis | Q24563457 | ||
| PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse | Q24619841 | ||
| The myosin superfamily at a glance. | Q27011868 | ||
| Molecular Basis of Filamin A-FilGAP Interaction and Its Impairment in Congenital Disorders Associated with Filamin A Mutations | Q27654191 | ||
| Calcium regulates podocyte actin dynamics | Q27692627 | ||
| The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors | Q27860467 | ||
| Cell migration: integrating signals from front to back | Q27860670 | ||
| Cellular motility driven by assembly and disassembly of actin filaments | Q27860676 | ||
| Cdc42/Rac1-dependent activation of the p21-activated kinase (PAK) regulates human platelet lamellipodia spreading: implication of the cortical-actin binding protein cortactin | Q44230899 | ||
| ARHGAP25, a novel Rac GTPase-activating protein, regulates phagocytosis in human neutrophilic granulocytes. | Q54338457 | ||
| Cell Migration: An Overview | Q54966338 | ||
| The small GTP-binding protein rac regulates growth factor-induced membrane ruffling | Q27861063 | ||
| Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia | Q27861126 | ||
| Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1 | Q28219213 | ||
| Non-muscle myosin II takes centre stage in cell adhesion and migration | Q28262326 | ||
| A short history of blebbing | Q28292242 | ||
| Rac activation and inactivation control plasticity of tumor cell movement | Q28299776 | ||
| PIP3, PIP2, and cell movement--similar messages, different meanings? | Q28366133 | ||
| The weak complex between RhoGAP protein ARHGAP22 and signal regulatory protein 14-3-3 has 1:2 stoichiometry and a single peptide binding mode | Q28482855 | ||
| Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis | Q28504659 | ||
| Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration | Q28508256 | ||
| Rho and Rac take center stage | Q28645748 | ||
| Inhibition of myosin light chain kinase by p21-activated kinase | Q28678502 | ||
| Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas | Q29030077 | ||
| Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics | Q29615714 | ||
| Biology of the p21-activated kinases | Q29616035 | ||
| Cell migration: Rho GTPases lead the way | Q29616711 | ||
| Stretching single talin rod molecules activates vinculin binding | Q29617762 | ||
| Cell adhesion: integrating cytoskeletal dynamics and cellular tension | Q29618066 | ||
| Coordination of Rho GTPase activities during cell protrusion | Q29618432 | ||
| Spatiotemporal dynamics of RhoA activity in migrating cells | Q29618433 | ||
| Rapid leukocyte migration by integrin-independent flowing and squeezing | Q29620345 | ||
| Localized RhoA activation as a requirement for the induction of membrane ruffling | Q30476117 | ||
| FilGAP, a Rho/Rho-associated protein kinase-regulated GTPase-activating protein for Rac, controls tumor cell migration | Q30529774 | ||
| Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor. | Q30539004 | ||
| Structural basis of filamin A functions | Q33308469 | ||
| TiGER: a database for tissue-specific gene expression and regulation | Q33341488 | ||
| Phosphoinositide binding domains: embracing 3-phosphate | Q33684004 | ||
| Dicing with dogma: de-branching the lamellipodium | Q33690284 | ||
| ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability | Q33706377 | ||
| Filamins in mechanosensing and signaling | Q33900830 | ||
| The Rac1- and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actin | Q33930483 | ||
| Small G-protein networks: their crosstalk and signal cascades. | Q34057932 | ||
| Actin dynamics and turnover in cell motility. | Q34205343 | ||
| Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells | Q34324446 | ||
| Characterization of a novel GTPase-activating protein associated with focal adhesions and the actin cytoskeleton | Q34378405 | ||
| The molecular requirements for cytokinesis | Q34404139 | ||
| Neutrophil polarization: spatiotemporal dynamics of RhoA activity support a self-organizing mechanism | Q34574438 | ||
| The filamins: organizers of cell structure and function | Q34891266 | ||
| Temporal and spatial regulation of chemotaxis | Q34984894 | ||
| Phosphoinositide regulation of the actin cytoskeleton | Q35019759 | ||
| Identification of RhoGAP22 as an Akt-dependent regulator of cell motility in response to insulin | Q35598809 | ||
| Cytoskeletal remodeling in leukocyte function | Q35608092 | ||
| Protein kinase C and the regulation of the actin cytoskeleton | Q36234425 | ||
| p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts | Q36256616 | ||
| Electron microscopy and 3D reconstruction reveals filamin Ig domain binding to F-actin | Q36413111 | ||
| Dynamic force sensing of filamin revealed in single-molecule experiments | Q36438361 | ||
| Inhibition of filamin-A reduces cancer metastatic potential | Q36503992 | ||
| Rapid signal transduction in living cells is a unique feature of mechanotransduction. | Q36638646 | ||
| Current knowledge of the large RhoGAP family of proteins | Q36707513 | ||
| The regulation of cell motility and chemotaxis by phospholipid signaling | Q37089555 | ||
| Molecular mechanisms of phagocytic uptake in mammalian cells. | Q37103162 | ||
| The role of FilGAP-filamin A interactions in mechanoprotection | Q37112662 | ||
| Rho GTPases in cancer cell biology | Q37156024 | ||
| Understanding PTEN regulation: PIP2, polarity and protein stability | Q37270444 | ||
| Proteolytic interstitial cell migration: a five-step process. | Q37372558 | ||
| Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion | Q37374521 | ||
| Control of actin filament treadmilling in cell motility | Q37700675 | ||
| RHO GTPase signaling for axon extension: is prenylation important? | Q37793980 | ||
| Rho GTPases as regulators of morphological neuroplasticity | Q37860720 | ||
| Role of Rho GTPases and their regulators in cancer progression | Q37881626 | ||
| Life at the leading edge | Q37894186 | ||
| Biomechanical regulation of contractility: spatial control and dynamics | Q37961392 | ||
| Directed cell invasion and migration during metastasis | Q37972432 | ||
| Roles for actin assembly in endocytosis. | Q38015894 | ||
| Rho family GTPases | Q38061989 | ||
| Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A. | Q38880148 | ||
| The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2. | Q39283013 | ||
| The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase | Q39454531 | ||
| Nonmuscle actin-binding proteins | Q39507803 | ||
| Actin can reorganize into podosomes in aortic endothelial cells, a process controlled by Cdc42 and RhoA. | Q39887636 | ||
| Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts | Q40182543 | ||
| p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho. | Q40203974 | ||
| Antagonistic cross-talk between Rac and Cdc42 GTPases regulates generation of reactive oxygen species | Q40559852 | ||
| p68RacGAP is a novel GTPase-activating protein that interacts with vascular endothelial zinc finger-1 and modulates endothelial cell capillary formation. | Q40589652 | ||
| Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior | Q40915141 | ||
| Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading | Q40918517 | ||
| ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts | Q41954269 | ||
| The structure of the GPIb-filamin A complex. | Q42741839 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell morphology | Q66568582 |
| cell migration | Q189092 | ||
| P1104 | number of pages | 9 | |
| P304 | page(s) | 17-25 | |
| P577 | publication date | 2013-07-01 | |
| P1433 | published in | Biochemical Journal | Q864221 |
| P1476 | title | FilGAP and its close relatives: a mediator of Rho-Rac antagonism that regulates cell morphology and migration | |
| P478 | volume | 453 |
| Q33707949 | A Rho-associated coiled-coil containing kinases (ROCK) inhibitor, Y-27632, enhances adhesion, viability and differentiation of human term placenta-derived trophoblasts in vitro |
| Q38608946 | ADP ribosylation factor 6 (Arf6) acts through FilGAP protein to down-regulate Rac protein and regulates plasma membrane blebbing |
| Q35199316 | ADP-ribosylation factor 6 (ARF6) bidirectionally regulates dendritic spine formation depending on neuronal maturation and activity |
| Q35188950 | ARHGAP22 localizes at endosomes and regulates actin cytoskeleton |
| Q37588375 | ARHGAP24 inhibits cell cycle progression, induces apoptosis and suppresses invasion in renal cell carcinoma |
| Q36471533 | An adventitious interaction of filamin A with RhoGDI2(Tyr153Glu) |
| Q35347031 | Antibody-validated proteins in inflamed islets of fulminant type 1 diabetes profiled by laser-capture microdissection followed by mass spectrometry |
| Q36999018 | Cyclic Mechanical Loading Is Essential for Rac1-Mediated Elongation and Remodeling of the Embryonic Mitral Valve |
| Q30276221 | Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS. |
| Q88447482 | Direct multiplex imaging and optogenetics of Rho GTPases enabled by near-infrared FRET |
| Q52928859 | Effect of Sema4D on microglial function in middle cerebral artery occlusion mice. |
| Q35755363 | FilGAP, a Rac-specific Rho GTPase-activating protein, is a novel prognostic factor for follicular lymphoma |
| Q93039069 | HBx-K130M/V131I Promotes Liver Cancer in Transgenic Mice via AKT/FOXO1 Signaling Pathway and Arachidonic Acid Metabolism |
| Q26823123 | Integrin cytoplasmic tail interactions |
| Q35934889 | KSHV gB associated RGD interactions promote attachment of cells by inhibiting the potential migratory signals induced by the disintegrin-like domain |
| Q47771892 | Kalirin reduction rescues psychosis-associated behavioral deficits in APPswe/PSEN1dE9 transgenic mice |
| Q30360988 | PTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility. |
| Q34490263 | Phosphoproteome profiling of the macrophage response to different toll-like receptor ligands identifies differences in global phosphorylation dynamics. |
| Q38836141 | Phosphorylation of Serine 402 Regulates RacGAP Protein Activity of FilGAP Protein |
| Q92451703 | Possible cooption of a VEGF-driven tubulogenesis program for biomineralization in echinoderms |
| Q48687874 | Rac1 and RhoA: Networks, loops and bistability. |
| Q37429828 | Rac1/RhoA antagonism defines cell-to-cell heterogeneity during epidermal morphogenesis in nematodes. |
| Q30734428 | Rapid Remodeling of Invadosomes by Gi-coupled Receptors: DISSECTING THE ROLE OF Rho GTPases. |
| Q26992281 | Rho GAPs and GEFs: controling switches in endothelial cell adhesion |
| Q60309933 | Rho GTPase Activating Protein 24 (ARHGAP24) Regulates the Anti-Cancer Activity of Sorafenib Against Breast Cancer MDA-MB-231 Cells via the Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathway |
| Q35890184 | Src Family Tyrosine Kinase Signaling Regulates FilGAP through Association with RBM10. |
| Q30622385 | Structurally governed cell mechanotransduction through multiscale modeling |
| Q43548953 | The RacGAP protein FilGAP is a negative regulator of chemokine-promoted lymphocyte migration |
| Q37222533 | The RhoE/ROCK/ARHGAP25 signaling pathway controls cell invasion by inhibition of Rac activity |
| Q26751231 | The dynamics of spatio-temporal Rho GTPase signaling: formation of signaling patterns |
| Q26825105 | The on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migration |
| Q38735665 | The role of FilGAP, a Rac-specific Rho-GTPase-activating protein, in tumor progression and behavior of astrocytomas |
| Q38170173 | The role of the non-canonical Wnt-planar cell polarity pathway in neural crest migration |
| Q38471353 | The sarcomeric M-region: a molecular command center for diverse cellular processes |
| Q50956857 | The shift in GH3 cell shape and cell motility is dependent on MLCK and ROCK. |
| Q50897216 | Unraveling a model of TCL/RhoJ allosterism using TC10 reverse chimeras. |
| Q30572197 | Valvular dystrophy associated filamin A mutations reveal a new role of its first repeats in small-GTPase regulation |
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