The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors (scientific article (publication date: 7 August 1992))

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Q37371588	Bombesin-induced gastrin release from canine G cells is stimulated by Ca2+ but not by protein kinase C, and is enhanced by disruption of rho/cytoskeletal pathways
Q36604031	Bordetella bronchiseptica dermonecrotizing toxin induces reorganization of actin stress fibers through deamidation of Gln-63 of the GTP-binding protein Rho.
Q71825235	Bordetella bronchiseptica dermonecrotizing toxin stimulates assembly of actin stress fibers and focal adhesions by modifying the small GTP-binding protein rho
Q42832573	Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin
Q34810123	Breaking the neuronal sphere: regulation of the actin cytoskeleton in neuritogenesis
Q24337472	Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity
Q39607954	Buckling of actin stress fibers: a new wrinkle in the cytoskeletal tapestry
Q28755150	Building the actin cytoskeleton: filopodia contribute to the construction of contractile bundles in the lamella
Q38328989	C3 toxin activates the stress signaling pathways, JNK and p38, but antagonizes the activation of AP-1 in rat-1 cells
Q58779385	CASP4/caspase-11 promotes autophagosome formation in response to bacterial infection
Q42799565	CCK-A receptor activates RhoA through G alpha 12/13 in NIH3T3 cells
Q24522594	CDC42 and FGD1 cause distinct signaling and transforming activities
Q41147249	CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1.
Q36236091	CDC42 and Rac1 control different actin-dependent processes in the Drosophila wing disc epithelium.
Q22009896	CMS: an adapter molecule involved in cytoskeletal rearrangements
Q34046726	CXCL12 induces connective tissue growth factor expression in human lung fibroblasts through the Rac1/ERK, JNK, and AP-1 pathways
Q35987292	CXCL16/CXCR6 chemokine signaling mediates breast cancer progression by pERK1/2-dependent mechanisms
Q50094770	Ca2+-sensing receptor induces Rho kinase-mediated actin stress fiber assembly and altered cell morphology, but not in response to aromatic amino acids.
Q39280745	Cadherins function during the collective cell migration of Xenopus Cranial Neural Crest cells: revisiting the role of E-cadherin
Q41326668	Calbindin expression in renal tubular epithelial cells. Altered sodium phosphate co-transport in association with cytoskeletal rearrangement
Q39776480	Calcineurin inhibitors activate the proto-oncogene Ras and promote protumorigenic signals in renal cancer cells
Q29614247	Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
Q36915358	Caldesmon inhibits nonmuscle cell contractility and interferes with the formation of focal adhesions
Q42828538	Calyculin-A induces focal adhesion assembly and tyrosine phosphorylation of p125(Fak), p130(Cas), and paxillin in Swiss 3T3 cells
Q90429712	Cancer Cells Resist Mechanical Destruction in Circulation via RhoA/Actomyosin-Dependent Mechano-Adaptation
Q39877226	Cannabinoid Receptor 1 Mediates Homing of Bone Marrow-Derived Mesenchymal Stem Cells Triggered by Chronic Liver Injury
Q40880335	Carbonylation and disassembly of the F-actin cytoskeleton in oxidant induced barrier dysfunction and its prevention by epidermal growth factor and transforming growth factor alpha in a human colonic cell line
Q41856989	Cardiac progenitor migration and specification: The dual function of Wnts.
Q28281154	Cas and NEDD9 Contribute to Tumor Progression through Dynamic Regulation of the Cytoskeleton
Q42566933	Casein kinase iγ2 impairs fibroblasts actin stress fibers formation and delays cell cycle progression in g1.
Q24554338	Caspase 3 cleavage of the Ste20-related kinase SLK releases and activates an apoptosis-inducing kinase domain and an actin-disassembling region
Q28210013	Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing
Q30654973	CdGAP regulates cell migration and adhesion dynamics in two-and three-dimensional matrix environments
Q30176009	CdGAP, a novel proline-rich GTPase-activating protein for Cdc42 and Rac.
Q28217513	Cdc42 and Rac1 are necessary for autotaxin-induced tumor cell motility in A2058 melanoma cells
Q30160270	Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L.
Q30662472	Cdc42 and RhoA reveal different spatio-temporal dynamics upon local stimulation with Semaphorin-3A.
Q39135444	Cdc42 and p190RhoGAP activation by CCN2 regulates cell spreading and polarity and induces actin disassembly in migrating keratinocytes.
Q52648244	Cdc42 controls primary mesenchyme cell morphogenesis in the sea urchin embryo.
Q39313136	Cdc42 in actin dynamics: An ordered pathway governed by complex equilibria and directional effector handover
Q24291871	Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex
Q40868100	Cdc42 is required for PIP(2)-induced actin polymerization and early development but not for cell viability
Q47937942	Cdc42 is required for membrane dependent actin polymerization in vitro
Q40022461	Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation
Q42135654	Cdc42- and IRSp53-dependent contractile filopodia tether presumptive lens and retina to coordinate epithelial invagination
Q27939243	Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity
Q24290738	Cdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actin
Q89401359	Cell Biology and Microbiology: A Continuous Cross-Feeding
Q51334188	Cell Entry of C3 Exoenzyme from Clostridium botulinum.
Q27003951	Cell adhesion and mechanical stimulation in the regulation of mesenchymal stem cell differentiation
Q35107552	Cell and molecular biology of myoblast fusion
Q39674970	Cell attachment to the extracellular matrix induces proteasomal degradation of p21(CIP1) via Cdc42/Rac1 signaling
Q40301712	Cell distribution of stress fibres in response to the geometry of the adhesive environment
Q39444763	Cell growth inhibition by farnesyltransferase inhibitors is mediated by gain of geranylgeranylated RhoB.
Q31071346	Cell invasion by Neisseria meningitidis requires a functional interplay between the focal adhesion kinase, Src and cortactin
Q59134742	Cell metabolism regulates integrin mechanosensing via an SLC3A2-dependent sphingolipid biosynthesis pathway
Q30309537	Cell migration in slice cultures
Q29616711	Cell migration: Rho GTPases lead the way
Q27860682	Cell migration: a physically integrated molecular process
Q35314068	Cell morphology and focal adhesion location alters internal cell stress
Q29011830	Cell motility mediated by rho and rho-associated protein kinase plays a critical role in intrahepatic metastasis of human hepatocellular carcinoma
Q36233701	Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis
Q30489289	Cell polarity triggered by cell-cell adhesion via E-cadherin
Q34445847	Cell polarization directed by extracellular cues in yeast
Q40623580	Cell surface receptors activate p21-activated kinase 1 via multiple Ras and PI3-kinase-dependent pathways
Q34483657	Cell surface transglutaminase promotes RhoA activation via integrin clustering and suppression of the Src-p190RhoGAP signaling pathway
Q36236847	Cell type-specific roles for Cdc42, Rac, and RhoL in Drosophila oogenesis
Q28269278	Cell-contact-dependent signalling in axon growth and guidance: Eph receptor tyrosine kinases and receptor protein tyrosine phosphatase beta
Q71973663	Cell-permeable ceramides prevent the activation of phospholipase D by ADP-ribosylation factor and RhoA
Q71855290	Cell-substrate and cell-cell interactions differently regulate cytoskeletal and extracellular matrix protein gene expression
Q29617095	Cells lying on a bed of microneedles: an approach to isolate mechanical force
Q38170082	Cellular and molecular mechanisms underlying blood vessel lumen formation
Q40952373	Cellular consequences of thrombin-receptor activation
Q34235539	Cellular cytoskeleton dynamics modulates non-viral gene delivery through RhoGTPases
Q40983033	Cellular signaling pathways and cytoskeletal organization.
Q71819960	Cell‐cycle‐dependent invasion in vitro by rat ascites hepatoma cells
Q26849566	Cerebral cavernous malformation is a vascular disease associated with activated RhoA signaling
Q24807354	Changes in extracellular matrix (ECM) and ECM-associated proteins in the metastatic progression of prostate cancer
Q33808584	Changes in membrane trafficking and actin dynamics during axon formation in cultured hippocampal neurons
Q58493540	Changes in the internal organization of the cell by microstructured substrates
Q36035075	Changes in tyrosine-phosphorylated p190 and its association with p120 type I and p100 type II rasGAPs during myelomonocytic differentiation of human leukemic cells.
Q37600445	Chapter 1. Focal adhesions: new angles on an old structure.
Q42815050	Characterization of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases
Q34319917	Characterization of Rad, a new member of Ras/GTPase superfamily, and its regulation by a unique GTPase-activating protein (GAP)-like activity
Q38292553	Characterization of RhoA-binding kinase ROKalpha implication of the pleckstrin homology domain in ROKalpha function using region-specific antibodies
Q28567098	Characterization of a Rac1- and RhoGDI-associated lipid kinase signaling complex
Q34378405	Characterization of a novel GTPase-activating protein associated with focal adhesions and the actin cytoskeleton
Q24321223	Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid
Q72649385	Characterization of botulinum C3-catalyzed ADP-ribosylation of rho proteins and identification of mammalian C3-like ADP-ribosyltransferase
Q30471916	Characterization of graf, the GTPase-activating protein for rho associated with focal adhesion kinase. Phosphorylation and possible regulation by mitogen-activated protein kinase.
Q34285790	Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2).
Q40805509	Characterization of rho GTPase family homologues in Drosophila melanogaster: overexpressing Rho1 in retinal cells causes a late developmental defect.
Q34536912	Characterization of the dermonecrotic toxin in members of the genus Bordetella
Q28246429	Characterization of the interactions between PDZ domains of the protein-tyrosine phosphatase PTPL1 and the carboxyl-terminal tail of Fas
Q34379889	Characterization of the mitogen-activated protein kinase phosphorylation sites on the connexin-43 gap junction protein
Q48327335	Characterization of the toxin Plx2A, a RhoA-targeting ADP-ribosyltransferase produced by the honey bee pathogen Paenibacillus larvae
Q36620511	Characterization of tissue biomechanics and mechanical signaling in uterine leiomyoma
Q38297271	Chemoattractant-stimulated NF-kappaB activation is dependent on the low molecular weight GTPase RhoA.
Q34713881	Chemotactic signaling pathways in neutrophils: from receptor to actin assembly
Q51865955	Chick amniogenesis is mediated by an actin cable.
Q39570330	Chimeric clostridial cytotoxins: identification of the N-terminal region involved in protein substrate recognition.
Q42988167	Cholecystokinin-stimulated tyrosine phosphorylation of p125FAK and paxillin is mediated by phospholipase C-dependent and -independent mechanisms and requires the integrity of the actin cytoskeleton and participation of p21rho
Q34480718	Chondrocyte-matrix attachment complexes mediate survival and differentiation
Q37590318	Cif type III effector protein: a smart hijacker of the host cell cycle
Q35570996	Citron kinase, a RhoA effector, enhances HIV-1 virion production by modulating exocytosis
Q40023199	Cla4p, a Saccharomyces cerevisiae Cdc42p-activated kinase involved in cytokinesis, is activated at mitosis
Q40338138	Cleavage of focal adhesion proteins and PKCdelta during lovastatin-induced apoptosis in spontaneously immortalized rat brain neuroblasts
Q36987703	Clinical neurosciences in the decade of the brain: hypotheses in neuro-oncology. VEG/PF acts upon the actin cytoskeleton and is inhibited by dexamethasone: relevance to tumor angiogenesis and vasogenic edema.
Q22008553	Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases
Q30176506	Cloning and characterization of a rhoGAP homolog from Dictyostelium discoideum
Q36696593	Cloning and characterization of an ftsZ homologue from a bacterial symbiont of Drosophila melanogaster
Q43614970	Cloning and characterization of rac-like cDNAs from Arabidopsis thaliana.
Q28580961	Cloning of rat ARHGAP4/C1, a RhoGAP family member expressed in the nervous system that colocalizes with the Golgi complex and microtubules
Q30432123	Cloning, genomic organization and chromosomal assignment of the mouse p190-B gene
Q40616444	Clostridial ADP-ribosylating toxins: effects on ATP and GTP-binding proteins
Q37613674	Clostridial toxins
Q24522454	Clostridium difficile toxins: mechanism of action and role in disease
Q22253402	Clustering of beta(2)-integrins on human neutrophils activates dual signaling pathways to PtdIns 3-kinase
Q30539004	Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor.
Q24670491	Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2
Q28275839	Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization
Q24632940	Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation
Q27323698	Cofilin/Twinstar phosphorylation levels increase in response to impaired coenzyme a metabolism
Q39518901	Coiling phagocytosis of Borrelia burgdorferi by primary human macrophages is controlled by CDC42Hs and Rac1 and involves recruitment of Wiskott-Aldrich syndrome protein and Arp2/3 complex.
Q42824967	Collapsin response mediator protein switches RhoA and Rac1 morphology in N1E-115 neuroblastoma cells and is regulated by Rho kinase
Q36699881	Combined analysis of in situ hybridization, cell cycle and structural markers using reflectance and immunofluorescence confocal microscopy
Q30401385	Combining AFM and acoustic probes to reveal changes in the elastic stiffness tensor of living cells
Q24596866	Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion
Q41484305	Complex protein composition of isolated focal adhesions: a two-dimensional gel and database analysis
Q38331186	Complexity of trypanosomatid endocytosis pathways revealed by Rab4 and Rab5 isoforms in Trypanosoma brucei
Q47294328	Computational modeling of single-cell mechanics and cytoskeletal mechanobiology.
Q34119565	Concepts in Ras-directed therapy
Q37441470	Concordance and interaction of guanine nucleotide dissociation inhibitor (RhoGDI) with RhoA in oogenesis and early development of the sea urchin
Q35779901	Conditional lethality of a yeast strain expressing human RHOA in place of RHO1.
Q24291063	Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides
Q64056556	Congenital Defects in Actin Dynamics of Germinal Center B Cells
Q37374836	Constitutive activation of the gastrin-releasing peptide receptor expressed by the nonmalignant human colon epithelial cell line NCM460.
Q40649906	Constitutively Activated Rho Guanosine Triphosphatases Regulate the Growth and Morphology of Hairy Cell Leukemia Cells
Q44650518	Constitutively active Gq/11-coupled Receptors Enable Signaling by Co-expressed Gi/o-coupled Receptors
Q37361297	Constitutively active RhoA inhibits proliferation by retarding G(1) to S phase cell cycle progression and impairing cytokinesis
Q74595670	Constructing signal transduction pathways in Arabidopsis
Q63407310	Contact dynamics during keratocyte motility
Q39636352	Contractility dominates adhesive ligand density in regulating cellular de-adhesion and retraction kinetics
Q46979004	Contraction of tubulointerstitial fibrosis tissue in diabetic nephropathy, as demonstrated in an in vitro fibrosis model
Q37341003	Contribution of AZAP-Type Arf GAPs to cancer cell migration and invasion
Q24806593	Control of T lymphocyte morphology by the GTPase Rho.
Q57035785	Control of adhesion and protrusion in cell migration by Rho GTPases
Q28506168	Control of cyclin G2 mRNA expression by forkhead transcription factors: novel mechanism for cell cycle control by phosphoinositide 3-kinase and forkhead
Q38469173	Control of neurite outgrowth by RhoA inactivation
Q38320517	Control of pollen tube tip growth by a Rop GTPase-dependent pathway that leads to tip-localized calcium influx
Q36604038	Control of the cytokinetic apparatus by flux of the Rho GTPases
Q38266683	Control of vascular smooth muscle function by Src-family kinases and reactive oxygen species in health and disease.
Q54315572	Controlling major cellular processes of human mesenchymal stem cells using microwell structures.
Q34452252	Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex
Q24537174	Convergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway
Q42730844	Convergence of vitamin D and lysophosphatidic acid signaling in stimulating human osteoblast maturation
Q28587275	Cooperation between mDia1 and ROCK in Rho-induced actin reorganization
Q30446661	Cooperative effects of Rho and mechanical stretch on stress fiber organization
Q44243354	Cooperative regulation by Rac and Rho of agrin-induced acetylcholine receptor clustering in muscle cells
Q34112801	Coordinating cell fate and morphogenesis in Drosophila renal tubules
Q30167760	Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity
Q43516733	Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1.
Q36255219	Corequirement of specific phosphoinositides and small GTP-binding protein Cdc42 in inducing actin assembly in Xenopus egg extracts
Q30452380	Cortactin tyrosine phosphorylation requires Rac1 activity and association with the cortical actin cytoskeleton
Q34736520	Critical activities of Rac1 and Cdc42Hs in skeletal myogenesis: antagonistic effects of JNK and p38 pathways
Q35161063	Crk associates with a multimolecular Paxillin/GIT2/beta-PIX complex and promotes Rac-dependent relocalization of Paxillin to focal contacts
Q35964491	Cross talk between the bombesin neuropeptide receptor and Sonic hedgehog pathways in small cell lung carcinoma.
Q33887662	Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins
Q47367446	Crosstalk between WIP and Rho family GTPases.
Q28273527	Cryptic Rac-binding and p21(Cdc42Hs/Rac)-activated kinase phosphorylation sites of NADPH oxidase component p67(phox)
Q60072661	Cryptic sites in vinculin
Q24324015	Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP
Q40725666	Csk, a critical link of g protein signals to actin cytoskeletal reorganization
Q52522661	Cucurbitacin E-induced disruption of the actin and vimentin cytoskeleton in prostate carcinoma cells.
Q40538780	Curcumin inhibits cell motility and alters microfilament organization and function in prostate cancer cells
Q47917210	Curved microstructures promote osteogenesis of mesenchymal stem cells via the RhoA/ROCK pathway
Q41774906	Cyclic guanosine monophosphate-dependent protein kinase I promotes adhesion of primary vascular smooth muscle cells.
Q38323711	Cyclic tensile loading regulates human mesenchymal stem cell differentiation into neuron-like phenotype
Q41493003	Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling
Q42799730	Cyclooxygenase and cAMP-dependent protein kinase reorganize the actin cytoskeleton for motility in HeLa cells
Q90595284	Cysteinyl leukotriene 2 receptor promotes endothelial permeability, tumor angiogenesis, and metastasis
Q24548470	Cytokinesis in prokaryotes and eukaryotes: common principles and different solutions
Q41877559	Cytoplasmic p21(Cip1/WAF1) regulates neurite remodeling by inhibiting Rho-kinase activity
Q53458275	Cytoskeletal dynamics in response to tensile loading of mammalian axons.
Q37698266	Cytoskeletal mechanisms for breaking cellular symmetry
Q38342846	Cytoskeletal rearrangements and transcriptional activation of c-fos serum response element by Rho-kinase.
Q41889609	Cytoskeletal regulation of dermal regeneration
Q36921010	Cytoskeletal reorganization induced by engagement of the NG2 proteoglycan leads to cell spreading and migration
Q40673946	Cytoskeletal reorganization induced by insulin: involvement of Grb2/Ash, Ras and phosphatidylinositol 3-kinase signalling
Q89604987	Cytoskeleton and Nucleotide Signaling in Glioma C6 Cells
Q38015371	Cytoskeleton in mast cell signaling
Q42801859	Cytotoxic necrotizing factor 1 from Escherichia coli and dermonecrotic toxin from Bordetella bronchiseptica induce p21(rho)-dependent tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 cells
Q77148309	Cytotoxic necrotizing factor 1 from Escherichia coli: a toxin with a new intracellular activity for eukaryotic cells
Q40498408	Cytotoxic necrotizing factor 1 hinders skeletal muscle differentiation in vitro by perturbing the activation/deactivation balance of Rho GTPases.
Q33552763	Cytotoxic necrotizing factor from Escherichia coli induces RhoA-dependent expression of the cyclooxygenase-2 Gene
Q33592569	Cytotoxic necrotizing factor type 1 of uropathogenic Escherichia coli kills cultured human uroepithelial 5637 cells by an apoptotic mechanism
Q35199228	Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibers
Q34107593	DEF-1/ASAP1 is a GTPase-activating protein (GAP) for ARF1 that enhances cell motility through a GAP-dependent mechanism
Q34306137	DEF6, a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA.
Q36667927	Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras
Q43597884	Dbl and the Rho GTPases activate NF kappa B by I kappa B kinase (IKK)-dependent and IKK-independent pathways
Q41374941	Dbl family proteins
Q35529057	De novo assembly and characterization of Muscovy duck liver transcriptome and analysis of differentially regulated genes in response to heat stress
Q42441134	Deactivation of ROCK-II by Y-27632 enhances basolateral pancreatic enzyme secretion and acute pancreatitis induced by CCK analogues
Q37044614	Deconstructing the mechanisms and consequences of TGF-β-induced EMT during cancer progression
Q46517603	Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction
Q39851862	Deleted in liver cancer 1 (DLC1) utilizes a novel binding site for Tensin2 PTB domain interaction and is required for tumor-suppressive function
Q24533631	Deleted in liver cancer 2 (DLC2) suppresses cell transformation by means of inhibition of RhoA activity
Q89510824	Deletion of the Nucleotide Exchange Factor Vav3 Enhances Axonal Complexity and Synapse Formation but Tampers Activity of Hippocampal Neuronal Networks In Vitro
Q35226546	Dental enamel structure is altered by expression of dominant negative RhoA in ameloblasts
Q34407283	Deregulation of HEF1 impairs M-phase progression by disrupting the RhoA activation cycle
Q36807980	Detergent solubility defines an alternative itinerary for a subpopulation of PDGF beta receptors
Q42834903	Determination of GTP loading on Rac and Cdc42 in platelets and fibroblasts
Q57446974	Determination of GTP loading on Rho
Q36946766	Development of farnesyltransferase inhibitors for clinical cancer therapy: focus on hematologic malignancies
Q36429603	Development of the farnesyltransferase inhibitor tipifarnib for therapy of hematologic malignancies
Q41888779	Developmental expression of three small GTPases in the mouse eye.
Q35131671	Diabetic neuropathy and nerve regeneration
Q28646114	Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling
Q42837177	Dictyostelium IQGAP-related protein specifically involved in the completion of cytokinesis
Q47828379	Different regions of Rho determine Rho-selective binding of different classes of Rho target molecules.
Q24653005	Differential effects of B cell receptor and B cell receptor-FcgammaRIIB1 engagement on docking of Csk to GTPase-activating protein (GAP)-associated p62
Q40802580	Differential endocytotic characteristics of a novel human B/DC cell line HBM-Noda: effective macropinocytic and phagocytic function rather than scavenging function
Q40938132	Differential expression of RAB5A in human lung adenocarcinoma cells with different metastasis potential
Q38347340	Differential expression of Rho family GTP-binding proteins and protein kinase C isozymes during C6 glial cell differentiation
Q48045746	Differential expression of distinct members of Rho family GTP-binding proteins during neuronal development: identification of Rac1B, a new neural-specific member of the family
Q71825118	Differential growth state‐dependent regulation of plasminogen activator inhibitor type‐1 expression in senescent IMR‐90 human diploid fibroblasts
Q24674800	Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding
Q28263808	Differential properties of D4/LyGDI versus RhoGDI: phosphorylation and rho GTPase selectivity
Q36010015	Differential regulation of actin microfilaments by human MICAL proteins
Q40643747	Differential regulation of junctional complex assembly in renal epithelial cell lines
Q42829086	Differential requirement for Rho family GTPases in an oncogenic insulin-like growth factor-I receptor-induced cell transformation
Q42806034	Differential translocation of rho family GTPases by lysophosphatidic acid, endothelin-1, and platelet-derived growth factor
Q60687729	Differentiation of monocyte-derived dendritic cells is associated with upregulation and activation of Rac-1 small GTPase
Q30944927	Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif
Q35384122	Direct genetic demonstration of G alpha 13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement.
Q24291941	Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF
Q42828475	Direct involvement of the small GTP-binding protein Rho in lbc oncogene function
Q33822281	Direct measurement of intracellular pressure
Q100958722	Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivo
Q40640840	Directional motility induced by epidermal growth factor requires Cdc42.
Q36063668	Discovery of a novel ROCK2 inhibitor with anti-migration effects via docking and high-content drug screening
Q44839303	Disruption of STAT3 signaling leads to tumor cell invasion through alterations of homotypic cell-cell adhesion complexes
Q30481637	Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase
Q34250571	Dissecting regional variations in stress fiber mechanics in living cells with laser nanosurgery
Q34756529	Dissociation of FAK/p130(CAS)/c-Src complex during mitosis: role of mitosis-specific serine phosphorylation of FAK
Q36549580	Distinct Rho GTPase activities regulate epithelial cell localization of the adhesion molecule CEACAM1: involvement of the CEACAM1 transmembrane domain
Q30472765	Distinct cellular effects and interactions of the Rho-family GTPase TC10.
Q36916636	Distinct effects of Rac1 on differentiation of primary avian myoblasts
Q30175365	Distinct expression patterns and transforming properties of multiple isoforms of Ost, an exchange factor for RhoA and Cdc42.
Q73691283	Distinct functions of Rho and Rac are required for convergent extension during Xenopus gastrulation
Q42817866	Distinct role of phosphatidylinositol 3-kinase and Rho family GTPases in Vav3-induced cell transformation, cell motility, and morphological changes
Q33849349	Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress
Q42824542	Distinct roles for the two Rho GDP/GTP exchange factor domains of kalirin in regulation of neurite growth and neuronal morphology.
Q24299983	Distinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure.
Q27312590	Distinctive Effects of Cytochalasin B in Chick Primary Myoblasts and Fibroblasts
Q92688358	Distinctive requirement of PKCε in the control of Rho GTPases in epithelial and mesenchymally transformed lung cancer cells
Q41431319	Distribution and functions of platelet-derived growth factors and their receptors during embryogenesis
Q28570033	Distribution of Rho family GTPases in the adult rat hippocampus and cerebellum
Q40732521	Diverse effects of RacV12 on cell transformation by Raf: partial inhibition of morphological transformation versus deregulation of cell cycle control
Q39021212	Down regulation of RhoC by microRNA-138 results in de-activation of FAK, Src and Erk1/2 signaling pathway in head and neck squamous cell carcinoma
Q40626756	DroVav, the Drosophila melanogaster homologue of the mammalian Vav proteins, serves as a signal transducer protein in the Rac and DER pathways
Q24676790	Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization
Q48596074	Drosophila protein kinase N (Pkn) is a negative regulator of actin-myosin activity during oogenesis.
Q36576992	Drug insight: Bisphosphonates for postmenopausal osteoporosis
Q30846580	Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation.
Q24795847	Drugs in development: bisphosphonates and metalloproteinase inhibitors
Q43559142	Dual effects of lysophosphatidic acid on human airway smooth muscle cell proliferation and survival
Q42496449	Dual regulation of Rho and Rac by p120 catenin controls adipocyte plasma membrane trafficking
Q33902903	Dual regulation of actin rearrangement through lysophosphatidic acid receptor in neuroblast cell lines: actin depolymerization by Ca(2+)-alpha-actinin and polymerization by rho
Q35616009	Dual role for RhoA in suppression and induction of cytokines in the human neutrophil
Q47996690	Dual role of Ras and Rho proteins: at the cutting edge of life and death
Q36293708	Dual stimulation of Ras/mitogen-activated protein kinase and RhoA by cell adhesion to fibronectin supports growth factor-stimulated cell cycle progression
Q22008768	Duet is a novel serine/threonine kinase with Dbl-Homology (DH) and Pleckstrin-Homology (PH) domains
Q44526847	Duroquinone reduction during passage through the pulmonary circulation
Q47154984	Dynamic Reorganization of the Cytoskeleton during Apoptosis: The Two Coffins Hypothesis
Q33927041	Dynamic actin-based epithelial adhesion and cell matching during Drosophila dorsal closure.
Q47072853	Dynamic analysis of actin cable function during Drosophila dorsal closure
Q34731335	Dynamic analysis of dorsal closure in Drosophila: from genetics to cell biology
Q24567910	Dynamic functions of RhoA in tumor cell migration and invasion
Q27325533	Dynamic modeling of cell migration and spreading behaviors on fibronectin coated planar substrates and micropatterned geometries
Q37823095	Dynamics of the Rho-family small GTPases in actin regulation and motility
Q55158837	Dysregulation of 5-hydroxytryptamine 6 receptor accelerates maturation of bone-resorbing osteoclasts and induces bone loss.
Q41121879	E-cadherin engagement stimulates tyrosine phosphorylation
Q40997372	EAST, a novel EGF receptor substrate, associates with focal adhesions and actin fibers
Q29347138	EBP50 is involved in the regulation of vascular smooth muscle cell migration and cytokinesis
Q39900849	ECM compliance regulates osteogenesis by influencing MAPK signaling downstream of RhoA and ROCK.
Q47934687	EGF induces recycling membrane to form ruffles
Q40786481	EGF receptor function is required in late G(1) for cell cycle progression induced by bombesin and bradykinin
Q78173207	EGF stimulates tyrosine phosphorylation of focal adhesion kinase (p125FAK) and paxillin in rat pancreatic acini by a phospholipase C-independent process that depends on phosphatidylinositol 3-kinase, the small GTP-binding protein, p21rho, and the in
Q28284396	ERK activation of p21 activated kinase-1 (Pak1) is critical for medulloblastoma cell migration
Q30557039	ERK and phosphoinositide 3-kinase temporally coordinate different modes of actin-based motility during embryonic wound healing
Q36741254	ERK5 promotes Src-induced podosome formation by limiting Rho activation
Q52177842	Ectopic expression of constitutively activated Ral GTPase inhibits cell shape changes during Drosophila eye development.
Q52617162	Effect of C3 transferase on human adipose-derived stem cells.
Q41778338	Effect of age on the role of Rho-kinase in short-term partial bladder outlet obstruction
Q58098144	Effect of protein kinase inhibitor H-7 on the contractility, integrity, and membrane anchorage of the microfilament system
Q47792504	Effects of Bacterial Toxins on Small GTP-binding Proteins
Q35527190	Effects of Clostridium difficile toxin A and toxin B on phospholipase D activation in human promyelocytic leukemic HL60 cells.
Q37472287	Effects of constitutively active GTPases on fibroblast behavior
Q34001170	Effects of cytotoxic necrotizing factor 1 and lethal toxin on actin cytoskeleton and VE-cadherin localization in human endothelial cell monolayers.
Q42081316	Effects of hemagglutinin-neuraminidase protein mutations on cell-cell fusion mediated by human parainfluenza type 2 virus
Q35953972	Effects of methionine on the cytoplasmic distribution of actin and tubulin during neural tube closure in rat embryos
Q57909984	Effects of microinjected small GTPases on the actin cytoskeleton of human neutrophils
Q36256216	Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity
Q28510995	Elastin induces myofibrillogenesis via a specific domain, VGVAPG
Q34466272	Elevated levels of ornithine decarboxylase cooperate with Raf/ERK activation to convert normal keratinocytes into invasive malignant cells
Q53175668	Elevated phosphatase of regenerating liver 3 (PRL-3) promotes cytoskeleton reorganization, cell migration and invasion in endometrial stromal cells from endometrioma.
Q63364715	Embryo Morphogenesis and the Role of the Actin Cytoskeleton
Q37308644	Emerging roles of sumoylation in the regulation of actin, microtubules, intermediate filaments, and septins
Q36149239	Ena/VASP is required for endothelial barrier function in vivo
Q30445163	Endogenous ARF6 interacts with Rac1 upon angiotensin II stimulation to regulate membrane ruffling and cell migration
Q30435481	Endogenous RhoG is rapidly activated after epidermal growth factor stimulation through multiple guanine-nucleotide exchange factors
Q41145924	Endosome dynamics regulated by a Rho protein.
Q57372161	Endostatin Associates with Lipid Rafts and Induces Reorganization of the Actin Cytoskeleton via Down-regulation of RhoA Activity
Q34259083	Endothelial cell migration during murine yolk sac vascular remodeling occurs by means of a Rac1 and FAK activation pathway in vivo
Q73031500	Endothelial cell mitogenesis induced by LPA: inhibition by thrombospondin-1 and thrombospondin-2
Q48415018	Endothelial cell-derived endothelin-1 is involved in abnormal scar formation by dermal fibroblasts through RhoA/Rho-kinase pathway.
Q44232451	Endothelial contraction and monolayer hyperpermeability are regulated by Src kinase
Q42832592	Endothelial differentiation gene-2 receptor is involved in lysophosphatidic acid-dependent control of 3T3F442A preadipocyte proliferation and spreading
Q42048403	Endothelium-targeted overexpression of heat shock protein 27 ameliorates blood-brain barrier disruption after ischemic brain injury.
Q34348884	Engineered materials and the cellular microenvironment: a strengthening interface between cell biology and bioengineering
Q30311858	Engulfment of Apoptotic Cells Is Negatively Regulated by Rho-mediated Signaling
Q27674377	Entamoeba histolytica Rho1 Regulates Actin Polymerization through a Divergent, Diaphanous-Related Formin
Q41852828	Epac as a novel effector of airway smooth muscle relaxation
Q37971530	Eph/ephrin signaling in cell-cell and cell-substrate adhesion.
Q42529862	EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells
Q40631883	Epidermal Growth Factor-dependent Regulation of Cdc42 Is Mediated by the Src Tyrosine Kinase
Q28387833	Epidermal growth factor activates the Rho GTPase-activating protein (GAP) Deleted in Liver Cancer 1 via focal adhesion kinase and protein phosphatase 2A
Q28581924	Epidermal growth factor modulates tyrosine phosphorylation of p130Cas. Involvement of phosphatidylinositol 3'-kinase and actin cytoskeleton
Q36234800	Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement
Q77701735	Epidermal growth factor receptor-mediated motility in fibroblasts
Q42833147	Epidermal growth factor-induced activation and translocation of c-Src to the cytoskeleton depends on the actin binding domain of the EGF-receptor.
Q43862589	Epinephrine inhibits invasion of oral squamous carcinoma cells by modulating intracellular cAMP.
Q42462935	Epithelial cell spreading induced by hepatocyte growth factor influences paxillin protein synthesis and posttranslational modification
Q61444530	Epithelial to Mesenchymal transition, eIF2α phosphorylation and Hsp70 expression enable greater tolerance in A549 cells to TiO over ZnO nanoparticles
Q36399326	Epithelial-mesenchymal transition in lung cancer: is tobacco the "smoking gun"?
Q37330718	ErbB receptors and cell polarity: new pathways and paradigms for understanding cell migration and invasion
Q39571444	Escherichia coli cytotoxic necrotizing factor 1 effaces microvilli and decreases transmigration of polymorphonuclear leukocytes in intestinal T84 epithelial cell monolayers
Q40016730	Escherichia coli cytotoxic necrotizing factor 1 inhibits intestinal epithelial wound healing in vitro after mechanical injury.
Q35443167	Escherichia coli cytotoxic necrotizing factor 1: evidence for induction of actin assembly by constitutive activation of the p21 Rho GTPase
Q34586498	EspO1-2 regulates EspM2-mediated RhoA activity to stabilize formation of focal adhesions in enterohemorrhagic Escherichia coli-infected host cells
Q36352233	Essential function of PTP-PEST during mouse embryonic vascularization, mesenchyme formation, neurogenesis and early liver development
Q36880922	Essential functions of ezrin in maintenance of cell shape and lamellipodial extension in normal and transformed fibroblasts
Q41116555	Essential role of Rac GTPase in hydrogen peroxide-induced activation of c-fos serum response element
Q34085488	Establishment of neuronal polarity: lessons from cultured hippocampal neurons
Q40192271	Establishment of stable human fibroblast cell lines constitutively expressing active Rho-GTPases
Q40549125	Estrogen receptor activation at serine 305 is sufficient to upregulate cyclin D1 in breast cancer cells.
Q52519795	Evidence for Rho-mediated agonist stimulation of phospholipase D in rat1 fibroblasts. Effects of Clostridium botulinum C3 exoenzyme.
Q42816004	Evidence for a calpeptin-sensitive protein-tyrosine phosphatase upstream of the small GTPase Rho. A novel role for the calpain inhibitor calpeptin in the inhibition of protein-tyrosine phosphatases
Q72283055	Evidence for a glycoprotein IIb-IIIa- and aggregation-independent mechanism of phosphatidylinositol 3',4'-bisphosphate synthesis in human platelets
Q33736262	Evidence for the Presence of a Low Mr GTP-binding Protein, ram p25, in Human Platelet Membranes
Q28568931	Evidence for the involvement of Tiam1 in axon formation
Q51190458	Evidence for the role of cell stiffness in modulation of volume-regulated anion channels.
Q42056986	Evidence that atypical protein kinase C-lambda and atypical protein kinase C-zeta participate in Ras-mediated reorganization of the F-actin cytoskeleton.
Q36342597	Evidence that beta3 integrin-induced Rac activation involves the calpain-dependent formation of integrin clusters that are distinct from the focal complexes and focal adhesions that form as Rac and RhoA become active
Q38288609	Evidence that farnesyltransferase inhibitors suppress Ras transformation by interfering with Rho activity
Q45076830	Evidence that the branched-chain alpha-keto acids accumulating in maple syrup urine disease induce morphological alterations and death in cultured astrocytes from rat cerebral cortex
Q77788248	Exertion of tractional force requires the coordinated up-regulation of cell contractility and adhesion
Q41769175	Exoenzyme S shows selective ADP-ribosylation and GTPase-activating protein (GAP) activities towards small GTPases in vivo
Q60368043	Explaining Aberrations of Cell Structure and Cell Signaling in Cancer Using Complex Adaptive Systems
Q37133680	Exploring mechanisms involved in renal tubular sensing of mechanical stretch following ureteric obstruction
Q57283597	Exposure of tumor necrosis factor-α to luminal membrane of bovine brain capillary endothelial cells cocultured with astrocytes induces a delayed increase of permeability and cytoplasmic stress fiber formation of actin
Q41176522	Expression cloning of lsc, a novel oncogene with structural similarities to the Dbl family of guanine nucleotide exchange factors
Q48874872	Expression of Rho-family GTPases (Rac, cdc42, RhoA) and their association with p-21 activated kinase in adult rat peripheral nerve.
Q24647211	Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes
Q36374631	Expression of cortactin and focal adhesion kinase in colorectal adenocarcinoma: correlation with clinicopathologic parameters and their prognostic implication
Q45738829	Expression of herpes simplex virus type 2 US3 affects the Cdc42/Rac pathway and attenuates c-Jun N-terminal kinase activation
Q34079370	Expression of microbial virulence proteins in Saccharomyces cerevisiae models mammalian infection
Q52194022	Expression of mixed lineage kinase-1 in pancreatic beta-cell lines at different stages of maturation and during embryonic pancreas development.
Q36831360	Expression of phosphorylated heat shock protein 27 during corneal epithelial wound healing.
Q42807393	Expression of the SRF gene occurs through a Ras/Sp/SRF-mediated-mechanism in response to serum growth signals
Q33783051	Expression of the pRb-binding regions of E1A enables efficient transformation of primary epithelial cells by v-src
Q26745687	Extracellular Matrix Revisited: Roles in Tissue Engineering
Q91869885	Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration
Q24554321	Extracellular signal-regulated kinase binds to TFII-I and regulates its activation of the c-fos promoter
Q24299646	Extracellular signal-regulated kinase mediates phosphorylation of tropomyosin-1 to promote cytoskeleton remodeling in response to oxidative stress: impact on membrane blebbing
Q30433710	Extracellular signal-regulated kinase promotes Rho-dependent focal adhesion formation by suppressing p190A RhoGAP.
Q28550544	Extracting Diffusive States of Rho GTPase in Live Cells: Towards In Vivo Biochemistry
Q35775396	Ezrin/radixin/moesin proteins and Rho GTPase signalling in leucocytes
Q24652635	FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles
Q50337087	FMNL1 promotes proliferation and migration of leukemia cells.
Q24551450	FRL, a novel formin-related protein, binds to Rac and regulates cell motility and survival of macrophages
Q28301106	Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases
Q64266322	Far-infrared radiation stimulates platelet-derived growth factor mediated skeletal muscle cell migration through extracellular matrix-integrin signaling
Q35949189	Farnesyl diphosphate synthase: a novel genotype association with bone mineral density in elderly women
Q34783592	Farnesyl transferase inhibitors as anticancer agents
Q34571777	Farnesyl transferase inhibitors: a novel targeted tnerapy for cancer
Q41462575	Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton
Q46584631	Fasudil hydrochloride hydrate, a Rho-kinase (ROCK) inhibitor, suppresses collagen production and enhances collagenase activity in hepatic stellate cells
Q34648508	Fibroblast cytoskeletal remodeling contributes to connective tissue tension
Q28211919	Fibroblast growth factor-inducible-14 is induced in axotomized neurons and promotes neurite outgrowth
Q36316799	Fibroblast mechanics in 3D collagen matrices
Q34661460	Fibroblasts probe substrate rigidity with filopodia extensions before occupying an area
Q42825954	Fibronectin Growth Factor-Binding Domains Are Required for Fibroblast Survival
Q42480091	Fibronectin's central cell-binding domain supports focal adhesion formation and Rho signal transduction
Q37983629	Fibroproliferative disorders and their mechanobiology
Q38114125	FilGAP and its close relatives: a mediator of Rho-Rac antagonism that regulates cell morphology and migration
Q34243424	Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion
Q37625700	Fission yeast pak1+ encodes a protein kinase that interacts with Cdc42p and is involved in the control of cell polarity and mating.
Q54278580	Fluid flow forces and rhoA regulate fibrous development of the atrioventricular valves.
Q54496111	Fluid flow stress induced contraction and re-spread of mesenchymal stem cells: a microfluidic study.
Q40733286	Focal adhesion as a signal transduction organelle
Q30440310	Focal adhesion kinase as a regulator of cell tension in the progression of cancer
Q41841768	Focal adhesion kinase-dependent regulation of adhesive forces involves vinculin recruitment to focal adhesions
Q34160823	Focal adhesion kinases: interest in immunoendocrinology, developmental biology, and cancer
Q26777662	Focal adhesions, stress fibers and mechanical tension
Q47969134	Focal adhesions: a personal perspective on a half century of progress
Q40606432	Focal contact clustering in osteoblastic cells under mechanical stresses: microgravity and cyclic deformation
Q24679102	Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism
Q34480190	Forces on adhesive contacts affect cell function
Q43548707	Formation of stress fibres in human endothelial cells infected with Bartonella bacilliformis is associated with altered morphology, impaired migration and defects in cell morphogenesis
Q38219067	Formins as effector proteins of Rho GTPases
Q41032320	From RAS to RHO: The making of the great cell biologist Alan Hall (1952-2015).
Q26824081	From mechanical force to RhoA activation
Q47740307	Full-spreading platelets induced by the recombinant rhodostomin are via binding to integrins and correlated with FAK phosphorylation
Q33745278	Function of EWS-POU5F1 in sarcomagenesis and tumor cell maintenance
Q28137707	Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF
Q30529390	Functional proteomic analysis of long-term growth factor stimulation and receptor tyrosine kinase coactivation in Swiss 3T3 fibroblasts
Q31640177	Functions of a new family of sphingosine-1-phosphate receptors
Q28141120	Functions of a rho-specific guanine nucleotide exchange factor in neurite retraction. Possible role of a proline-rich motif of KIAA0380 in localization
Q34580340	G Protein and β-arrestin signaling bias at the ghrelin receptor
Q35745964	G Protein-Coupled Receptor and RhoA-Stimulated Transcriptional Responses: Links to Inflammation, Differentiation, and Cell Proliferation
Q41216039	G alpha 13 stimulates Na+-H+ exchange through distinct Cdc42-dependent and RhoA-dependent pathways
Q26825769	G protein-coupled receptors as oncogenic signals in glioma: emerging therapeutic avenues
Q34475580	G-protein-coupled receptor cell signaling pathways mediating embryonic chick retinal growth cone collapse induced by lysophosphatidic acid and sphingosine-1-phosphate
Q77726460	G-protein-stimulated phospholipase D activity is inhibited by lethal toxin from Clostridium sordellii in HL-60 cells
Q26863411	G17V RHOA: Genetic evidence of GTP-unbound RHOA playing a role in tumorigenesis in T cells
Q30908412	G2A is an oncogenic G protein-coupled receptor
Q33904931	GAP activity of the Yersinia YopE cytotoxin specifically targets the Rho pathway: a mechanism for disruption of actin microfilament structure
Q44035202	GAP junctional channel inhibition alters actin organization and calcium propagation in rat cultured astrocytes
Q38171331	GAP-independent functions of DLC1 in metastasis
Q39622579	GC-binding factor 2 interacts with dishevelled and regulates Wnt signaling pathways in human carcinoma cell lines
Q34264512	GEF-H1 controls focal adhesion signaling that regulates mesenchymal stem cell lineage commitment.
Q27650491	GIT1 Paxillin-binding Domain Is a Four-helix Bundle, and It Binds to Both Paxillin LD2 and LD4 Motifs
Q55446160	GRAMD1B regulates cell migration in breast cancer cells through JAK/STAT and Akt signaling.
Q41690566	Galpha(13) stimulates Rho-dependent activation of the cyclooxygenase-2 promoter
Q41035564	Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate
Q40763145	Ganglioside GD1a inhibits HGF-induced motility and scattering of cancer cells through suppression of tyrosine phosphorylation of c-Met
Q74643559	Gastrin stimulates the formation of a p60Src/p125FAK complex upstream of the phosphatidylinositol 3-kinase signaling pathway
Q24324765	Gbeta gamma-independent coupling of alpha2-adrenergic receptor to p21(rhoA) in preadipocytes
Q42639554	Gelsolin is a downstream effector of rac for fibroblast motility
Q33716119	GeneChip analyses of global transcriptional responses of murine macrophages to the lethal toxin of Bacillus anthracis
Q36691528	Genes encoding small GTP-binding proteins analogous to mammalian rac are preferentially expressed in developing cotton fibers
Q27933966	Genetic analysis of the Saccharomyces cerevisiae RHO3 gene, encoding a rho-type small GTPase, provides evidence for a role in bud formation
Q53622986	Genetic deletion of Rac1 GTPase reveals its critical role in actin stress fiber formation and focal adhesion complex assembly.
Q40199543	Genetic variants in the genes encoding rho GTPases and related regulators predict cutaneous melanoma-specific survival.
Q30857023	Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells
Q28207593	Genomic organization of human myotonic dystrophy kinase-related Cdc42-binding kinase alpha reveals multiple alternative splicing and functional diversity
Q57365044	Giant hollow fiber formation through self-assembly of oppositely charged polyelectrolyte brushes and gold nanoparticles
Q46077153	Glucocorticoid down-regulation of RhoA is required for the steroid-induced organization of the junctional complex and tight junction formation in rat mammary epithelial tumor cells
Q34320713	Glycoprotein capture and quantitative phosphoproteomics indicate coordinated regulation of cell migration upon lysophosphatidic acid stimulation
Q34486740	Gonadotropin-releasing hormone receptor activates GTPase RhoA and inhibits cell invasion in the breast cancer cell line MDA-MB-231
Q37843684	Good fences make good neighbors: Gastrointestinal mucosal structure
Q39479633	Green tea polyphenol epigallocatechin gallate activates TRPA1 in an intestinal enteroendocrine cell line, STC-1.
Q30583756	Group choreography: mechanisms orchestrating the collective movement of border cells
Q40939409	Growth factor regulation of integrin-mediated cell motility
Q27931888	Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae.
Q42989978	Guanine nucleotide-dependent translocation of RhoA from cytosol to high affinity membrane binding sites in human erythrocytes
Q42490579	Guanosine 5'-3-O-(thio)triphosphate stimulates tyrosine phosphorylation of p125FAK and paxillin in permeabilized Swiss 3T3 cells. Role of p21rho
Q41821246	Gα13/PDZ-RhoGEF/RhoA signaling is essential for gastrin-releasing peptide receptor-mediated colon cancer cell migration
Q38957364	Gβγ Pathways in Cell Polarity and Migration Linked to Oncogenic GPCR Signaling: Potential Relevance in Tumor Microenvironment
Q30155981	HBx expression activates RhoA GTPase: impact on cell migration
Q48769009	HDAC6 and RhoA are novel players in Abeta-driven disruption of neuronal polarity.
Q40655023	HIF-1α mRNA and protein upregulation involves Rho GTPase expression during hypoxia in renal cell carcinoma
Q39417456	HIV-1 Tat triggers nuclear localization of ZO-1 via Rho signaling and cAMP response element-binding protein activation
Q35113720	HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation
Q36885797	HMG-CoA reductase inhibitors induce apoptosis in mouse proximal tubular cells in primary culture
Q33716915	HSP27 regulates fibroblast adhesion, motility, and matrix contraction
Q24681878	Healing of incisional wounds in the embryonic chick wing bud: characterization of the actin purse-string and demonstration of a requirement for Rho activation
Q55342961	Helical rotation of the diaphanous-related formin mDia1 generates actin filaments resistant to cofilin.
Q36747117	Hemolysin of uropathogenic Escherichia coli evokes extensive shedding of the uroepithelium and hemorrhage in bladder tissue within the first 24 hours after intraurethral inoculation of mice.
Q41901774	Heparanase Modulates Shh and Wnt3a Signaling in Human Medulloblastoma Cells
Q33924987	Heparanase-induced GEF-H1 signaling regulates the cytoskeletal dynamics of brain metastatic breast cancer cells
Q34559070	Hepatic stellate cells: role in microcirculation and pathophysiology of portal hypertension
Q40987305	Hepatocyte growth factor and Madin-Darby canine kidney cells: in vitro models of epithelial cell movement and morphogenesis
Q74298471	Heterogeneity of DNA content and expression of cell cycle genes in axenically growing Entamoeba histolytica HM1:IMSS clone A
Q38288726	High activity of serum response factor in the mesenchymal transition of epithelial tumor cells is regulated by RhoA signaling
Q36638652	High blood pressure arising from a defect in vascular function.
Q36918650	High expression of integrin β6 in association with the Rho-Rac pathway identifies a poor prognostic subgroup within HER2 amplified breast cancers.
Q27329542	High glucose-mediated oxidative stress impairs cell migration
Q64074586	High-Throughput, Time-Resolved Mechanical Phenotyping of Prostate Cancer Cells
Q34702690	High-content profiling of cell responsiveness to graded substrates based on combinyatorially variant polymers
Q27729869	High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides
Q38104533	Hijacking of Rho GTPases during bacterial infection
Q28237794	Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential
Q37474507	Homocysteine promotes vascular smooth muscle cell migration by induction of the adipokine resistin
Q33840324	How WASP-family proteins and the Arp2/3 complex convert intracellular signals into cytoskeletal structures
Q83299629	How a paper on RAC set the standard
Q78599812	How do microtubules guide migrating cells?
Q37851547	How important are Rho GTPases in neurosecretion?
Q37378895	Hsp70 regulation on Nox4/p22phox and cytoskeletal integrity as an effect of losartan in vascular smooth muscle cells
Q91645190	Human Recombinant Arginase I [HuArgI (Co)-PEG5000]-Induced Arginine Depletion Inhibits Colorectal Cancer Cell Migration and Invasion
Q24323015	Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
Q35854433	Human adenovirus type 9 E4 open reading frame 1 encodes a cytoplasmic transforming protein capable of increasing the oncogenicity of CREF cells
Q24323041	Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae
Q24312369	Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells
Q38337972	Hyperosmotic stress induces rapid focal adhesion kinase phosphorylation at tyrosines 397 and 577. Role of Src family kinases and Rho family GTPases
Q34776387	Hypo- and hyperglycemia impair endothelial cell actin alignment and nitric oxide synthase activation in response to shear stress.
Q47806822	Hypoxia alters biophysical properties of endothelial cells via p38 MAPK- and Rho kinase-dependent pathways
Q24308783	ICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrin
Q90402561	ILK supports RhoA/ROCK-mediated contractility of human intestinal epithelial crypt cells by inducing the fibrillogenesis of endogenous soluble fibronectin during the spreading process
Q90262742	IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models
Q24679845	IQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilaments
Q24324005	IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs
Q30310902	IQGAPs: integrators of the cytoskeleton, cell adhesion machinery, and signaling networks
Q44271588	Id-1 induces cell invasiveness in immortalized epithelial cells by regulating cadherin switching and Rho GTPases
Q38289451	Identification and Molecular Cloning of a p21cdc42/rac1-activated Serine/Threonine Kinase That Is Rapidly Activated by Thrombin in Platelets
Q24651430	Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases
Q28141833	Identification and characterization of a novel MAP kinase kinase kinase, MLTK
Q28571750	Identification and characterization of a novel Rho GTPase activating protein implicated in receptor-mediated endocytosis
Q28587982	Identification and characterization of a novel Ste20/germinal center kinase-related kinase, polyploidy-associated protein kinase
Q28646556	Identification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42
Q42824590	Identification of Glu173 as the critical amino acid residue for the ADP-ribosyltransferase activity of Clostridium botulinum C3 exoenzyme
Q28289355	Identification of a mouse p21Cdc42/Rac activated kinase
Q35313440	Identification of a negative regulatory region for the exchange activity and characterization of T332I mutant of Rho guanine nucleotide exchange factor 10 (ARHGEF10).
Q28115627	Identification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1
Q42829719	Identification of a novel growth factor-like lipid, 1-O-cis-alk-1'-enyl-2-lyso-sn-glycero-3-phosphate (alkenyl-GP) that is present in commercial sphingolipid preparations.
Q24316282	Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation
Q28115356	Identification of a novel protein with GDP dissociation inhibitor activity for the ras-like proteins CDC42Hs and rac I
Q24679938	Identification of a novel, putative Rho-specific GDP/GTP exchange factor and a RhoA-binding protein: control of neuronal morphology
Q28284529	Identification of a putative effector for Cdc42Hs with high sequence similarity to the RasGAP-related protein IQGAP1 and a Cdc42Hs binding partner with similarity to IQGAP2
Q33518293	Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay
Q53930600	Identification of drug‐regulated genes in osteosarcoma cells
Q38478215	Identification of filamin as a novel ligand for caveolin-1: evidence for the organization of caveolin-1-associated membrane domains by the actin cytoskeleton
Q24321633	Identification of the Rho-binding domain of p160ROCK, a Rho-associated coiled-coil containing protein kinase
Q30447293	Identification of the deleted in liver cancer 1 gene, DLC1, as a candidate meningioma tumor suppressor.
Q28585658	Identification of the stef gene that encodes a novel guanine nucleotide exchange factor specific for Rac1
Q34168146	Identification of transcription factors regulating CTNNAL1 expression in human bronchial epithelial cells
Q30476471	Imaging native beta-actin mRNA in motile fibroblasts
Q91943122	Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging
Q40799685	Immediate early genes induced by H-Ras in thyroid cells
Q44965413	Immunocytochemical localization of polyamines during attachment and spreading of retinal pigment epithelial and intestinal epithelial cells
Q36288200	Impaired integrin-mediated adhesion and signaling in fibroblasts expressing a dominant-negative mutant PTP1B.
Q42363534	Impairment of PDGF-induced chemotaxis by extracellular α-synuclein through selective inhibition of Rac1 activation
Q38307283	Implication of a small GTPase Rac1 in the activation of c-Jun N-terminal kinase and heat shock factor in response to heat shock
Q33927829	Implication of atypical protein kinase C isozymes lambda and zeta in Ras mediated reorganization of the actin cytoskeleton and cyclin D1-induction
Q38151113	Implications of Rho GTPase Signaling in Glioma Cell Invasion and Tumor Progression
Q42492146	Importance of spatial activation of Cdc42 and rac small G proteins by frabin for microspike formation in MDCK cells
Q30445152	In response to protein load podocytes reorganize cytoskeleton and modulate endothelin-1 gene: implication for permselective dysfunction of chronic nephropathies
Q40929201	In vitro analysis of G-protein functions.
Q46675968	In vitro and in vivo assays to analyze the contribution of Rho kinase in angiogenesis
Q39654000	In vivo modifications of small GTPase Rac and Cdc42 by Bordetella dermonecrotic toxin
Q36382566	In vivo requirement of protein prenylation for maintenance of retinal cytoarchitecture and photoreceptor structure.
Q78166417	Inactivation of Rho signaling pathway promotes CNS axon regeneration
Q40874259	Increased Kit/SCF receptor induced mitogenicity but abolished cell motility after inhibition of protein kinase C.
Q48504388	Increased expression of mRNAs for microtubule disassembly molecules during nerve regeneration.
Q24648337	Increased expression of the Ras suppressor Rsu-1 enhances Erk-2 activation and inhibits Jun kinase activation
Q28571878	Increased phosphorylation of myosin light chain associated with slow-to-fast transition in rat soleus
Q41142229	Induced PAI-1 mRNA expression and targeted protein accumulation are early G1 events in serum-stimulated rat kidney cells
Q39540274	Induced expression of Rnd3 is associated with transformation of polarized epithelial cells by the Raf-MEK-extracellular signal-regulated kinase pathway
Q73089665	Inducible membrane recruitment of small GTP-binding proteins by rapamycin-based system in living cells
Q34047215	Induction and regulation of epithelial-mesenchymal transitions
Q36313391	Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function
Q35006325	Induction of protein-protein interactions in live cells using light
Q48501594	Inductions of granulosa cell luteinization and cumulus expansion are dependent on the fibronectin-integrin pathway during ovulation process in mice.
Q39536911	Infection of human endothelial cells with Bartonella bacilliformis is dependent on Rho and results in activation of Rho.
Q33248082	Influence of simulated microgravity on the activation of the small GTPase Rho involved in cytoskeletal formation--molecular cloning and sequencing of bovine leukemia-associated guanine nucleotide exchange factor
Q41399114	Influence of tyrosine residues Y705 and Y807 on the transforming potency of the v-fms oncogene product of feline sarcoma virus
Q37980724	Inhibition and termination of physiological responses by GTPase activating proteins
Q41213243	Inhibition of Fc epsilon-RI-mediated activation of rat basophilic leukemia cells by Clostridium difficile toxin B (monoglucosyltransferase)
Q36233109	Inhibition of PMA-induced, LFA-1-dependent lymphocyte aggregation by ADP ribosylation of the small molecular weight GTP binding protein, rho.
Q74801438	Inhibition of Pollen Tube Elongation by Microinjected Anti-Rop1Ps Antibodies Suggests a Crucial Role for Rho-Type GTPases in the Control of Tip Growth
Q42805239	Inhibition of ROCK by RhoE.
Q34626070	Inhibition of Rac and ROCK signalling influence osteoblast adhesion, differentiation and mineralization on titanium topographies
Q37303350	Inhibition of Rac1 GTPase activity affects porcine oocyte maturation and early embryo development
Q36873446	Inhibition of Rho is required for cAMP-induced melanoma cell differentiation.
Q39635580	Inhibition of Rho-kinase abrogates migration of human transitional cell carcinoma cells: results of an in vitro study
Q30454295	Inhibition of RhoA translocation and calcium sensitization by in vivo ADP-ribosylation with the chimeric toxin DC3B
Q33292252	Inhibition of RhoA-mediated SRF activation by p116Rip
Q43812611	Inhibition of bone resorption by alendronate and risedronate does not require osteoclast apoptosis
Q37381921	Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation
Q43737962	Inhibition of geranylgeranylation blocks agonist-induced actin reorganization in human airway smooth muscle cells
Q54962948	Inhibition of in vitro tumor cell invasion by ginsenoside Rg3.
Q41450596	Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.
Q37252541	Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis
Q73565086	Inhibition of smooth muscle cell migration by the p21 cyclin-dependent kinase inhibitor (Cip1)
Q34167898	Inhibition of tumor growth and metastasis by non-small cell lung cancer cells transfected with cyclin D1-targeted siRNA
Q50731684	Inhibitory effects of tumor necrosis factor-alpha on migration of human periodontal ligament cells.
Q36159466	Inside view of cell locomotion through single-molecule: fast F-/G-actin cycle and G-actin regulation of polymer restoration
Q38043667	Inside-out, outside-in, and inside-outside-in: G protein signaling in integrin-mediated cell adhesion, spreading, and retraction.
Q36482254	Insights into the role of focal adhesion modulation in myogenic differentiation of human mesenchymal stem cells
Q46082447	Integrating focal adhesion dynamics, cytoskeleton remodeling, and actin motor activity for predicting cell migration on 3D curved surfaces of the extracellular matrix.
Q38769266	Integrative functional genomic analysis identifies epigenetically regulated fibromodulin as an essential gene for glioma cell migration
Q45995226	Integrin activation by R-ras.
Q41811902	Integrin alphavbeta5 regulates lung vascular permeability and pulmonary endothelial barrier function
Q34445932	Integrin beta 1 cytoplasmic domain dominant negative effects revealed by lysophosphatidic acid treatment
Q40924688	Integrin cytoplasmic interactions and bidirectional transmembrane signalling
Q30168812	Integrin engagement, the actin cytoskeleton, and c-Src are required for the calcitonin-induced tyrosine phosphorylation of paxillin and HEF1, but not for calcitonin-induced Erk1/2 phosphorylation
Q40939392	Integrin mediated signal transduction in oncogenesis: an overview
Q42137293	Integrin signaling switches the cytoskeletal and exocytic machinery that drives neuritogenesis
Q30445496	Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane
Q34084035	Integrin β1 regulates leiomyoma cytoskeletal integrity and growth
Q42159517	Integrin-dependent translocation of p160ROCK to cytoskeletal complex in thrombin-stimulated human platelets
Q38285373	Integrin-mediated adhesion and mechano-sensing in cutaneous wound healing.
Q30500235	Integrin-mediated adhesion regulates cell polarity and membrane protrusion through the Rho family of GTPases
Q30469063	Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins
Q36256316	Integrin-mediated signals regulated by members of the rho family of GTPases
Q30417364	Integrins in cell migration
Q37588229	Interaction between the human papillomavirus 16 E7 oncoprotein and gelsolin ignites cancer cell motility and invasiveness
Q30176948	Interaction of Ash/Grb-2 via its SH3 domains with neuron-specific p150 and p65
Q48829230	Interaction of G protein Gbetagamma dimers with small GTP-binding proteins of the Rho family.
Q24530109	Interaction of Nck-associated protein 1 with activated GTP-binding protein Rac
Q28297416	Interaction of PDZRhoGEF with microtubule-associated protein 1 light chains: link between microtubules, actin cytoskeleton, and neuronal polarity
Q28267082	Interaction of Rac1 with GTPase-activating proteins and putative effectors. A comparison with Cdc42 and RhoA
Q24646299	Interaction of activated Ras with Raf-1 alone may be sufficient for transformation of rat2 cells
Q30859001	Interaction of cofilin with triose-phosphate isomerase contributes glycolytic fuel for Na,K-ATPase via Rho-mediated signaling pathway
Q22011215	Interaction of the Grb7 adapter protein with Rnd1, a new member of the Rho family
Q51198177	Interaction-tailored cell aggregates in alginate hydrogels for enhanced chondrogenic differentiation.
Q30193735	Interactions among proteins involved in bud-site selection and bud-site assembly in Saccharomyces cerevisiae
Q27937191	Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast
Q41620130	Interference of Y-27632 on the signal transduction of transforming growth factor beta type 1 in ocular Tenon capsule fibroblasts
Q33822383	Interferon regulatory factor 6 regulates keratinocyte migration
Q36076782	Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases
Q47930467	Interleukin-1beta induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axis.
Q35152732	Interleukin-1β and tumor necrosis factor-α increase stiffness and impair contractile function of articular chondrocytes.
Q42814213	Interplay between Rac and Rho in the control of substrate contact dynamics
Q36065090	Intracellular Ascorbate Prevents Endothelial Barrier Permeabilization by Thrombin
Q33826088	Intracellular invasion by Orientia tsutsugamushi is mediated by integrin signaling and actin cytoskeleton rearrangements
Q24642838	Intracellular localization of the P21rho proteins
Q38495126	Intracellular pH modulation of ADF/cofilin proteins
Q42442226	Intracellular signal transduction modulating expression of plasminogen activator inhibitor-1 in adipocytes
Q34963694	Intracellular signaling in M-CSF-induced microglia activation: role of Iba1.
Q38423864	Intracellular signaling of cardiac fibroblasts
Q34081322	Intracellular signaling pathways that regulate dendritic spine morphogenesis
Q34888258	Intracystic papillary carcinoma of breast: interrelationship with in situ and invasive carcinoma and a proposal of pathogenesis: array comparative genomic hybridization study of 14 cases
Q44071370	Intravenous anesthetic, propofol inhibits invasion of cancer cells
Q42175059	Intrinsic, Pro-Apoptotic Effects of IGFBP-3 on Breast Cancer Cells are Reversible: Involvement of PKA, Rho, and Ceramide
Q28251084	Invadopodia: specialized cell structures for cancer invasion
Q30445881	Invasion and metastasis models for studying RhoGDI2 in bladder cancer
Q41024128	Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling
Q30008929	Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES.
Q35604332	Involvement of 14-3-3 proteins in the second epidermal growth factor-induced wave of Rac1 activation in the process of cell migration.
Q52774602	Involvement of ARHGEF10, GEF for RhoA, in Rab6/Rab8-mediating membrane traffic.
Q44620984	Involvement of Cdc42 signaling in apoA-I-induced cholesterol efflux
Q42823375	Involvement of Fyn tyrosine kinase in actin stress fiber formation in fibroblasts
Q41269587	Involvement of Ral GTPase in v-Src-induced phospholipase D activation
Q24682858	Involvement of Ras-related Rho proteins in the mechanisms of action of Clostridium difficile toxin A and toxin B
Q40752215	Involvement of Rho and tyrosine kinase in angiotensin II-induced actin reorganization in mesothelial cells
Q44551585	Involvement of Rho family G protein in the cell signaling for sperm incorporation during fertilization of mouse eggs: inhibition by Clostridium difficile toxin B.
Q42808427	Involvement of microtubules in the control of adhesion-dependent signal transduction.
Q44807455	Involvement of myosin II in dopamine-induced reorganization of the lactotroph cell's actin cytoskeleton
Q36658331	Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in cell motility
Q78015044	Involvement of small GTPases Rho and Rac in the invasion of rat ascites hepatoma cells
Q36236019	Involvement of the GTP binding protein Rho in constitutive endocytosis in Xenopus laevis oocytes
Q30472684	Involvement of the actin cytoskeleton and p21rho-family GTPases in the pathogenesis of the human protozoan parasite Entamoeba histolytica
Q41168817	Involvement of the small GTPase rho in integrin-mediated activation of mitogen-activated protein kinase.
Q36596684	Is caveolin-1 a viable therapeutic target to reduce cancer metastasis?
Q24336343	Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor
Q73089681	Isolation and in vitro contraction of stress fibers
Q24291308	Isolation of a novel human gene, ARHGAP9, encoding a rho-GTPase activating protein
Q36839179	Isolation of the gene coding for Caenorhabditis elegans Rac2 homologue, a Ras-related small GTP-binding protein
Q42809300	Isoprenylation of RhoB is necessary for its degradation. A novel determinant in the complex regulation of RhoB expression by the mevalonate pathway
Q36832518	Isotope coded protein labeling coupled immunoprecipitation (ICPL-IP): a novel approach for quantitative protein complex analysis from native tissue
Q24532273	Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells
Q24300105	Kank proteins: a new family of ankyrin-repeat domain-containing proteins
Q37530607	Kank proteins: structure, functions and diseases
Q24310007	Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signaling
Q30828274	Kinetics of recruitment and allosteric activation of ARHGEF25 isoforms by the heterotrimeric G-protein Gαq
Q35231177	Knockdown of Rab5a expression decreases cancer cell motility and invasion through integrin-mediated signaling pathway
Q45249905	Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells.
Q34528240	Knowing how to navigate: mechanisms of semaphorin signaling in the nervous system
Q34257595	LIM proteins in actin cytoskeleton mechanoresponse
Q35791590	LPA Induces Colon Cancer Cell Proliferation through a Cooperation between the ROCK and STAT-3 Pathways
Q42113269	LPA-induced mutually exclusive subcellular localization of active RhoA and Arp2 mRNA revealed by sequential FRET and FISH.
Q28205737	LPP, a LIM protein highly expressed in smooth muscle
Q33251283	Label-free and real-time cell-based kinase assay for screening selective and potent receptor tyrosine kinase inhibitors using microelectronic sensor array
Q41836547	Lamellipodia-based migrations of larval epithelial cells are required for normal closure of the adult epidermis of Drosophila
Q34601863	Leishmania donovani requires functional Cdc42 and Rac1 to prevent phagosomal maturation.
Q37000954	Leptin induces phagocytosis of apoptotic bodies by hepatic stellate cells via a Rho guanosine triphosphatase-dependent mechanism
Q42830742	Leucine zipper-mediated homodimerization of the p21-activated kinase-interacting factor, beta Pix. Implication for a role in cytoskeletal reorganization
Q32065080	Leukotriene D(4)-induced Rho-mediated actin reorganization in human bronchial smooth muscle cells
Q52539925	Leukotrienes and tyrosine phosphorylation mediate stretching-induced actin cytoskeletal remodeling in endothelial cells.
Q24319896	Leupaxin is similar to paxillin in focal adhesion targeting and tyrosine phosphorylation but has distinct roles in cell adhesion and spreading
Q34524341	Levels and values of lipoprotein-associated phospholipase A2, galectin-3, RhoA/ROCK, and endothelial progenitor cells in critical limb ischemia: pharmaco-therapeutic role of cilostazol and clopidogrel combination therapy.
Q41155438	Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein
Q71742493	Light-sensitive response in melanophores of Xenopus laevis: II.Rho is involved in light-induced melanin aggregation
Q24296713	Linear arrays of nuclear envelope proteins harness retrograde actin flow for nuclear movement.
Q35953069	Lipid-induced Muscle Insulin Resistance Is Mediated by GGPPS via Modulation of the RhoA/Rho Kinase Signaling Pathway
Q36735658	Lipids trigger changes in the elasticity of the cytoskeleton in plant cells: a cell optical displacement assay for live cell measurements
Q35747915	Lipoxins induce actin reorganization in monocytes and macrophages but not in neutrophils: differential involvement of rho GTPases
Q30579395	Listeria monocytogenes actin-based motility varies depending on subcellular location: a kinematic probe for cytoarchitecture.
Q37212922	Localization and translocation of RhoA protein in the human gastric cancer cell line SGC-7901.
Q74806222	Localization of a Rho GTPase Implies a Role in Tip Growth and Movement of the Generative Cell in Pollen Tubes
Q30476117	Localized RhoA activation as a requirement for the induction of membrane ruffling
Q73379033	Loss of Rho function in the thymus is accompanied by the development of thymic lymphoma
Q54577063	Loss of contraction force in dermal fibroblasts with aging due to decreases in myosin light chain phosphorylation enzymes.
Q41553540	Loss of giant obscurins alters breast epithelial cell mechanosensing of matrix stiffness
Q37536190	Loss of oncogenic ras expression does not correlate with loss of tumorigenicity in human cells
Q42798467	Low Doses of Curcuma longa Modulates Cell Migration and Cell-Cell Adhesion
Q53413063	Low-Intensity Pulsed Ultrasound Improves the Functional Properties of Cardiac Mesoangioblasts.
Q39237957	Low-Rac1 activity downregulates MC3T3-E1 osteoblastic cell motility on a nanoscale topography prepared on polystyrene substrates in vitro
Q24311993	Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes
Q30439694	Lysophosphatidic acid (LPA) and angiogenesis
Q36564705	Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer.
Q38328981	Lysophosphatidic acid activates NF-kappaB in fibroblasts. A requirement for multiple inputs
Q42160836	Lysophosphatidic acid activation of phosphatidylcholine-hydrolysing phospholipase D and actin polymerization by a pertussis toxin-sensitive mechanism
Q36236438	Lysophosphatidic acid and bFGF control different modes in proliferating myoblasts
Q37386811	Lysophosphatidic acid and microtubule-destabilizing agents stimulate fibronectin matrix assembly through Rho-dependent actin stress fiber formation and cell contraction
Q55479076	Lysophosphatidic acid depletes intracellular calcium stores different from those mediating capacitative calcium entry in C6 rat glioma cells.
Q39953910	Lysophosphatidic acid induced nuclear translocation of nuclear factor-kappaB in Panc-1 cells by mobilizing cytosolic free calcium
Q71833440	Lysophosphatidic acid induces inositol phosphate and calcium signals in exocrine cells from the avian nasal salt gland
Q42807086	Lysophosphatidic acid induces tyrosine phosphorylation and activation of MAP-kinase and focal adhesion kinase in cultured Swiss 3T3 cells
Q40458438	Lysophosphatidic acid inhibits anti-Fas-mediated apoptosis enhanced by actin depolymerization in epithelial ovarian cancer.
Q36136166	Lysophosphatidic acid is a chemoattractant for Dictyostelium discoideum amoebae.
Q37384485	Lysophosphatidic acid is a major serum noncytokine survival factor for murine macrophages which acts via the phosphatidylinositol 3-kinase signaling pathway
Q44833041	Lysophosphatidic acid modulates the regenerative responses of human gingival fibroblasts and enhances the actions of platelet-derived growth factor.
Q35081424	Lysophosphatidic acid possesses dual action in cell proliferation
Q40844684	Lysophosphatidic acid prevents apoptosis in fibroblasts via G(i)-protein-mediated activation of mitogen-activated protein kinase
Q28355993	Lysophosphatidic acid promotes phorbol-ester-induced apoptosis in TF-1 cells by interfering with adhesion
Q28579088	Lysophosphatidic acid rescues RhoA activation and phosphoinositides levels in astrocytes exposed to ethanol
Q73208292	Lysophosphatidic acid sensitizes mechanical stress-induced Ca2+ response via activation of phospholipase C and tyrosine kinase in cultured smooth muscle cells
Q30539772	Lysophosphatidic acid signaling may initiate fetal hydrocephalus.
Q42716792	Lysophosphatidic acid stimulates epidermal growth factor-family ectodomain shedding and paracrine signaling from human lung fibroblasts
Q42540355	Lysophosphatidic acid stimulates the G-protein-coupled receptor EDG-1 as a low affinity agonist
Q28609420	Lysophosphatidic acid synthesis and release
Q41336296	Lysophosphatidic acid-induced activation of protein Ser/Thr kinases in cultured rat 3Y1 fibroblasts. Possible involvement in rho p21-mediated signalling
Q73720961	M1 muscarinic acetylcholine receptors activate zif268 gene expression via small G-protein Rho-dependent and lambda-independent pathways in PC12D cells
Q40499329	MAP kinase pathways. Straight and narrow or tortuous and intersecting?
Q28580197	MAP kinase- and Rho-dependent signals interact to regulate gene expression but not actin morphology in cardiac muscle cells
Q41461105	MAP kinases in mitogenesis and development
Q22010458	MSE55, a Cdc42 effector protein, induces long cellular extensions in fibroblasts
Q39015094	MTSS1 is a metastasis driver in a subset of human melanomas
Q42817189	Macrophage/microglia-specific protein Iba1 enhances membrane ruffling and Rac activation via phospholipase C-gamma -dependent pathway
Q40978467	Major role for active extension in the formation of processes by ras-transformed fibroblasts
Q36030829	Mammalian cell invasion and intracellular trafficking by Trypanosoma cruzi infective forms
Q40242164	Mapping in vivo associations of cytoplasmic proteins with integrin beta 1 cytoplasmic domain mutants.
Q35669826	Mapping of Ras-related GTP-binding proteins by GTP overlay following two-dimensional gel electrophoresis.
Q35769380	Mapping of the C5a receptor signal transduction network in human neutrophils
Q36381371	Marching at the front and dragging behind: differential alphaVbeta3-integrin turnover regulates focal adhesion behavior
Q39574466	Mas oncogene signaling and transformation require the small GTP-binding protein Rac
Q37264167	Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells
Q40170846	Maspin controls mammary tumor cell migration through inhibiting Rac1 and Cdc42, but not the RhoA GTPase
Q26824518	Matrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasion
Q35007822	Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK-ERK linkage
Q38330900	Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase
Q35815864	Measuring traction forces of motile dendritic cells on micropost arrays
Q34990511	Mechanical integration of actin and adhesion dynamics in cell migration
Q36617270	Mechanical regulation of nuclear structure and function.
Q34727905	Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling.
Q38421231	Mechanically induced focal adhesion assembly amplifies anti-adipogenic pathways in mesenchymal stem cells
Q34830392	Mechanics of spreading cells probed by atomic force microscopy
Q33400987	Mechanics, malignancy, and metastasis: the force journey of a tumor cell
Q30175873	Mechanism of activation of Pak1 kinase by membrane localization
Q34237984	Mechanisms of epithelial fusion and repair.
Q42834452	Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant
Q35083913	Mechanisms of nitric oxide interplay with Rho GTPase family members in modulation of actin membrane dynamics in pericytes and fibroblasts
Q53988320	Mechanisms of sodium fluoride-induced endothelial cell barrier dysfunction: role of MLC phosphorylation.
Q33804105	Mechanisms of the epithelial-mesenchymal transition by TGF-beta
Q27026468	Mechanisms of the inward remodeling process in resistance vessels: is the actin cytoskeleton involved?
Q41224439	Mechanisms of wound healing in the embryo and fetus
Q64917063	Mechanobiological Feedback in Pulmonary Vascular Disease.
Q36748725	Mechanoregulation of gene expression in fibroblasts
Q41785271	Melanoma cell migration to type IV collagen requires activation of NF-kappaB
Q22010904	Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas
Q35866776	Membrane dynamics correlate with formation of signaling clusters during cell spreading
Q28579492	Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells
Q47576945	Merkel Cell Polyomavirus Small T Antigen Drives Cell Motility via Rho-GTPase-Induced Filopodium Formation
Q42953348	Merlin inhibits neurite outgrowth in the CNS.
Q43819584	Mesangial cell filamentous actin disassembly and hypocontractility in high glucose are mediated by PKC-zeta
Q34002994	Mesenchymal migration as a therapeutic target in glioblastoma
Q28140219	Met receptor tyrosine kinase: enhanced signaling through adapter proteins
Q77612818	Metal-ion stimulation and inhibition of lysophospholipase D which generates bioactive lysophosphatidic acid in rat plasma
Q37311433	Methamphetamine-induced occludin endocytosis is mediated by the Arp2/3 complex-regulated actin rearrangement
Q38912644	Methylation of PLCD1 and adenovirus-mediated PLCD1 overexpression elicits a gene therapy effect on human breast cancer
Q37645010	MicroRNA-126 inhibits colon cancer cell proliferation and invasion by targeting the chemokine (C-X-C motif) receptor 4 and Ras homolog gene family, member A, signaling pathway
Q42172409	MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach
Q35874543	MicroRNA-34a modulates cytoskeletal dynamics through regulating RhoA/Rac1 cross-talk in chondroblasts
Q36771820	MicroRNA-708-5p acts as a therapeutic agent against metastatic lung cancer.
Q34066508	Microbial toxins and the glycosylation of rho family GTPases
Q28610808	Microfilament reorganization during apoptosis: the role of Gas2, a possible substrate for ICE-like proteases
Q27336353	Microfluidic generated EGF-gradients induce chemokinesis of transplantable retinal progenitor cells via the JAK/STAT and PI3kinase signaling pathways
Q41245385	Microtubule dynamic turnover is suppressed during polarization and stimulated in hepatocyte growth factor scattered Madin-Darby canine kidney epithelial cells
Q34744466	Microtubule-dependent modulation of adhesion complex composition
Q43170361	Migrating anterior mesoderm cells and intercalating trunk mesoderm cells have distinct responses to Rho and Rac during Xenopus gastrulation.
Q44390049	Migration of human dental follicle cells in vitro
Q38839147	Minireview: Role of genetic changes of faciogenital dysplasia protein 1 in human disease
Q37386319	Mitogen-activated protein kinase/extracellular signal-regulated kinase 2 regulates cytoskeletal organization and chemotaxis via catalytic and microtubule-specific interactions
Q73168796	Modeling signal transduction in normal and cancer cells using complex adaptive systems
Q28080261	Modelling GTPase dynamics to understand RhoA-driven cancer cell invasion
Q36955886	Modulating the dysregulated migration of pulmonary arterial hypertensive smooth muscle cells with motif mimicking cell permeable peptides
Q38962538	Modulation of ERK5 is a novel mechanism by which Cdc42 regulates migration of breast cancer cells.
Q35619856	Modulation of HIV-1 replication by a novel RhoA effector activity
Q36289167	Modulation of beta1A integrin functions by tyrosine residues in the beta1 cytoplasmic domain
Q42942739	Modulation of cell adhesion by changes in alpha L beta 2 (LFA-1, CD11a/CD18) cytoplasmic domain/cytoskeleton interaction.
Q34233446	Modulation of cell interactions with extracellular matrix by lysophosphatidic acid and sphingosine 1-phosphate
Q36234881	Modulation of cell surface fibronectin assembly sites by lysophosphatidic acid
Q79148975	Modulation of cultured corneal keratocyte phenotype by growth factors/cytokines control in vitro contractility and extracellular matrix contraction
Q36957463	Modulation of endocytic traffic in polarized Madin-Darby canine kidney cells by the small GTPase RhoA.
Q34187901	Modulation of intestinal permeability: a novel and innovative approach for the oral delivery of drugs, macromolecules and antigens
Q41472012	Modulation of scatter factor/hepatocyte growth factor activity by cell-substratum adhesion
Q33921451	Molecular analysis of racE function in Dictyostelium
Q36725462	Molecular analysis of two Ypt/Rab-related sequences isolated from soybean (Glycine max) DNA libraries
Q34246740	Molecular biology of chronic myeloid leukemia
Q22010785	Molecular cloning and characterization of human trabeculin-alpha, a giant protein defining a new family of actin-binding proteins
Q36549762	Molecular cloning and characterization of rho, a ras-related small GTP-binding protein from the garden pea.
Q24324476	Molecular cloning and expression analysis of rat Rgs12 and Rgs14
Q36708551	Molecular cloning of Rab-related genes in the yeast Yarrowia lipolytica. Analysis of RYL1, an essential gene encoding a SEC4 homologue
Q24310333	Molecular cloning of a cDNA encoding a novel small GTP-binding protein
Q28289551	Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family
Q24306777	Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL
Q40722950	Molecular consequences of the BCR-ABL translocation in chronic myelogenous leukemia
Q42796987	Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells
Q41111086	Molecular mechanisms for focal adhesion assembly through regulation of protein-protein interactions
Q33632255	Molecular mechanisms of action of bisphosphonates.
Q36021576	Molecular mechanisms of glioma cell migration and invasion
Q35622988	Molecular mechanisms of host-pathogen interaction: entry and survival of mycobacteria in macrophages.
Q45107856	Molecular mechanisms of low intensity pulsed ultrasound in human skin fibroblasts
Q43073286	Molecular mechanisms underlying the anti-proliferative and anti-migratory effects of folate on homocysteine-challenged rat aortic smooth muscle cells
Q38104416	Molecular networks in melanoma invasion and metastasis.
Q35585465	Molecular parameters of head and neck cancer metastasis
Q36528894	Molecular pathways triggering glioma cell invasion
Q38682208	Molecular perturbation strategies to examine spatiotemporal features of Rho GEF and Rho GTPase activity in living cells.
Q34410331	Molecular physiology of the tensin brotherhood of integrin adaptor proteins
Q42797335	Monocyte adhesion and spreading on human endothelial cells is dependent on Rho-regulated receptor clustering
Q46679789	Morphological alterations and cell death provoked by the branched-chain alpha-amino acids accumulating in maple syrup urine disease in astrocytes from rat cerebral cortex
Q40949147	Morphological changes and detachment of adherent cells induced by p122, a GTPase-activating protein for Rho.
Q52571893	Morphological changes in the Golgi complex correlate with actin cytoskeleton rearrangements.
Q34872874	Morphological color changes in fish: regulation of pigment cell density and morphology
Q44294998	Morphological plasticity of olfactory ensheathing cells is regulated by cAMP and endothelin-1.
Q42815442	Morphological transformation induced by activation of the mitogen-activated protein kinase pathway requires suppression of the T-type Ca2+ channel
Q42484381	Motility and invasion are differentially modulated by Rho family GTPases
Q36739644	Motility-related proteins as markers for head and neck squamous cell cancer
Q28592732	Motorized RhoGAP myosin IXb (Myo9b) controls cell shape and motility
Q28512389	Mouse A6/twinfilin is an actin monomer-binding protein that localizes to the regions of rapid actin dynamics
Q92409391	Multifaceted Rho GTPase Signaling at the Endomembranes
Q30499347	Multinucleated giant cells from fibroblast cultures
Q38809211	Multiple mechanisms of 3D migration: the origins of plasticity
Q35952748	Multiple parallelisms in animal cytokinesis.
Q34180632	Multiple roles for Cdc42 in cell regulation
Q40295965	Multiple signaling pathways mediate compaction of collagen matrices by EGF-stimulated fibroblasts
Q39896662	Multiplex imaging of Rho family GTPase activities in living cells
Q40928721	Multisubunit receptors in the immune system and their association with the cytoskeleton: in search of functional significance
Q30194750	Mutagenesis of human profilin locates its poly(L-proline)-binding site to a hydrophobic patch of aromatic amino acids.
Q30192925	Mutant forms of growth factor-binding protein-2 reverse BCR-ABL-induced transformation
Q92736081	Mutant p53 on the Path to Metastasis
Q64121392	Mutant p53 regulates LPA signaling through lysophosphatidic acid phosphatase type 6
Q41133992	Mutations of Ros differentially effecting signal transduction pathways leading to cell growth versus transformation
Q47416824	Mycobacterium tuberculosis Mce3C promotes mycobacteria entry into macrophages through activation of β2 integrin-mediated signalling pathway.
Q36434018	Myocardin-Related Transcription Factor A and Yes-Associated Protein Exert Dual Control in G Protein-Coupled Receptor- and RhoA-Mediated Transcriptional Regulation and Cell Proliferation
Q35626103	Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts.
Q73401434	Myosin light chain kinase mediates sarcomere organization during cardiac hypertrophy in vitro
Q44124518	Myosin light chain phosphorylation and growth cone motility.
Q37216665	Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC
Q33291451	MyosinIIa contractility is required for maintenance of platelet structure during spreading on collagen and contributes to thrombus stability
Q24317262	Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization
Q73408342	Myotonic dystrophy protein kinase (DMPK) induces actin cytoskeletal reorganization and apoptotic-like blebbing in lens cells
Q24291086	Myotonic dystrophy protein kinase phosphorylates the myosin phosphatase targeting subunit and inhibits myosin phosphatase activity
Q30488554	NADPH oxidase 1 controls the persistence of directed cell migration by a Rho-dependent switch of alpha2/alpha3 integrins.
Q28538761	NAMPT-mediated salvage synthesis of NAD+ controls morphofunctional changes of macrophages
Q71555226	NDP kinase can modulate contraction of Dictyostelium cytoskeletons
Q35563136	NF2: the wizardry of merlin
Q39788587	NZO-3 expression causes global changes to actin cytoskeleton in Madin-Darby canine kidney cells: linking a tight junction protein to Rho GTPases
Q33948740	Na,K-ATPase activity is required for formation of tight junctions, desmosomes, and induction of polarity in epithelial cells
Q36901472	Na-H exchange acts downstream of RhoA to regulate integrin-induced cell adhesion and spreading
Q36081897	NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies.
Q36161401	Nanofibrillar scaffolds induce preferential activation of Rho GTPases in cerebral cortical astrocytes.
Q46310297	Nanoparticle size-specific actin rearrangement and barrier dysfunction of endothelial cells.
Q58742065	Nanoscale-Textured Tantalum Surfaces for Mammalian Cell Alignment
Q33948870	Natural biology of polyomavirus middle T antigen
Q30167854	Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton
Q30544951	Nephrons require Rho-kinase for proximal-distal polarity development
Q33788024	Neural crest cell-specific deletion of Rac1 results in defective cell-matrix interactions and severe craniofacial and cardiovascular malformations
Q35017623	Neurobiology of lysophosphatidic acid signaling
Q34759983	Neuronal cell shape and neurite initiation are regulated by the Ndr kinase SAX-1, a member of the Orb6/COT-1/warts serine/threonine kinase family
Q40284709	Neuropeptide-stimulated cell migration in prostate cancer cells is mediated by RhoA kinase signaling and inhibited by neutral endopeptidase
Q73266958	Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth
Q34131744	Neutrophil migration inhibitory properties of polyunsaturated fatty acids. The role of fatty acid structure, metabolism, and possible second messenger systems
Q38981722	New Aspects on Bacterial Effectors Targeting Rho GTPases
Q64969934	New insights into YAP/TAZ nucleo-cytoplasmic shuttling: new cancer therapeutic opportunities?
Q37783808	New insights into the dynamics of cell adhesions
Q24308319	Newly identified stress-responsive protein kinases, Krs-1 and Krs-2
Q46424997	Nicotinic acetylcholine receptor-mediated stimulation of endothelial cells results in the arrest of haematopoietic progenitor cells on endothelium
Q47407667	Non-visual arrestins regulate the focal adhesion formation via small GTPases RhoA and Rac1 independently of GPCRs
Q34762702	Noncanonical Notch function in motor axon guidance is mediated by Rac GTPase and the GEF1 domain of Trio
Q40773569	Noncanonical Wnt signaling regulates midline convergence of organ primordia during zebrafish development
Q77540552	Novel approaches for oral delivery of macromolecules
Q27930624	Novel protein kinases Ark1p and Prk1p associate with and regulate the cortical actin cytoskeleton in budding yeast.
Q33913667	Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility
Q24608984	Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression
Q34462072	Nuclear and cytoplasmic glycosylation.
Q37048514	Nuclear factor of activated T cells c1 mediates p21-activated kinase 1 activation in the modulation of chemokine-induced human aortic smooth muscle cell F-actin stress fiber formation, migration, and proliferation and injury-induced vascular wall re
Q38343118	Nuclear signalling by rac GTPase: essential role of phospholipase A2.
Q42825534	Oncogenic Ha-Ras-dependent mitogen-activated protein kinase activity requires signaling through the epidermal growth factor receptor
Q36561047	Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation
Q38613745	Opposite effects of insulin on focal adhesion proteins in 3T3-L1 adipocytes and in cells overexpressing the insulin receptor
Q40941485	Opposite regulation of transepithelial electrical resistance and paracellular permeability by Rho in Madin-Darby canine kidney cells
Q40772259	Optical waveguide lightmode spectroscopy as a new method to study adhesion of anchorage-dependent cells as an indicator of metabolic state
Q41089685	Optogenetic control of RhoA reveals zyxin-mediated elasticity of stress fibres.
Q34325910	Optogenetic protein clustering and signaling activation in mammalian cells
Q54058467	Organization of point contacts in neuronal growth cones.
Q40202300	Organized migration of epithelial cells requires control of adhesion and protrusion through Rho kinase effectors
Q36790372	Osteoclast molecular phenotyping by random cDNA sequencing
Q40415629	Outgrowth of neurites from NIE-115 neuroblastoma cells is prevented on repulsive substrates through the action of PAK.
Q37372936	Outside-in signaling in the chondrocyte. Nitric oxide disrupts fibronectin-induced assembly of a subplasmalemmal actin/rho A/focal adhesion kinase signaling complex.
Q36881341	Ovarian cancer G protein coupled receptor 1 suppresses cell migration of MCF7 breast cancer cells via a Gα12/13-Rho-Rac1 pathway
Q40725999	Over-expression of PAR-3 suppresses contact-mediated inhibition of cell migration in MDCK cells.
Q27310338	Overexpression of CTHRC1 in hepatocellular carcinoma promotes tumor invasion and predicts poor prognosis
Q42436147	Overexpression of RnRacGAP in Drosophila melanogaster deregulates cytoskeletal organisation in cellularising embryos and induces discrete imaginal phenotypes
Q36915169	Overexpression of a novel rho family GTPase, RacC, induces unusual actin-based structures and positively affects phagocytosis in Dictyostelium discoideum
Q34819599	Overexpression of kinase suppressor of Ras upregulates the high-molecular-weight tropomyosin isoforms in ras-transformed NIH 3T3 fibroblasts
Q36294989	Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas
Q30524150	Oxidized LDL/CD36 interaction induces loss of cell polarity and inhibits macrophage locomotion
Q35903570	Oxygen free radicals and redox biology of organelles
Q43683525	Oxytocin and lysophosphatidic acid induce stress fiber formation in human myometrial cells via a pathway involving Rho-kinase
Q35952627	PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation
Q30490902	PAK kinase regulates Rac GTPase and is a potential target in human schwannomas
Q24313368	PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
Q24540039	PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells
Q35920489	PDGF in gliomas: more than just a growth factor?
Q72735572	PDGF-mediated activation of phosphatidylinositol 3 kinase in human mesangial cells
Q48566438	PIPkins1, their substrates and their products: new functions for old enzymes.
Q28207652	PKC epsilon is associated with myosin IIA and actin in fibroblasts
Q42479271	PKCdelta regulates endothelial basal barrier function through modulation of RhoA GTPase activity
Q28277817	PKN associates and phosphorylates the head-rod domain of neurofilament protein
Q39010968	PLAGL2 regulates actin cytoskeletal architecture and cell migration
Q24318343	PLC-gamma1 and Rac1 coregulate EGF-induced cytoskeleton remodeling and cell migration
Q28301906	PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins
Q22011202	PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organization
Q24555751	PTEN as an effector in the signaling of antimigratory G protein-coupled receptor
Q34228582	PTEN inhibition improves wound healing in lung epithelia through changes in cellular mechanics that enhance migration
Q28217262	PYY-mediated fatty acid induced intestinal differentiation
Q27333195	Pak1 regulates the orientation of apical polarization and lumen formation by distinct pathways
Q28573207	Par-4: a new activator of myosin phosphatase
Q100512221	Partners in crime: POPX2 phosphatase and its interacting proteins in cancer
Q42817645	Pasteurella multocida toxin, a potent intracellularly acting mitogen, induces p125FAK and paxillin tyrosine phosphorylation, actin stress fiber formation, and focal contact assembly in Swiss 3T3 cells
Q37812728	Pathogen-mediated posttranslational modifications: A re-emerging field
Q37942128	Pathogens and polymers: microbe-host interactions illuminate the cytoskeleton
Q28078292	Pathophysiological Functions of Rnd3/RhoE
Q40715319	Pathways of Ras function: connections to the actin cytoskeleton.
Q90640157	Pattern-Dependent Mammalian Cell (Vero) Morphology on Tantalum/Silicon Oxide 3D Nanocomposites
Q24682031	Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling
Q42550725	Paxillin increases as retinoic acid or vitamin D3 induce HL-60 cell differentiation
Q42827022	Paxillin isoforms in mouse. Lack of the gamma isoform and developmentally specific beta isoform expression.
Q55503101	Peptide density targets and impedes triple negative breast cancer metastasis.
Q35724475	Pericyte chemomechanics and the angiogenic switch: insights into the pathogenesis of proliferative diabetic retinopathy?
Q27318097	Pericytes regulate vascular basement membrane remodeling and govern neutrophil extravasation during inflammation
Q28080692	Perspective of synaptic protection after post-infarction treatment with statins
Q34579500	Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides
Q71904032	Pharmacologic regulation of Dupuytren's fibroblast contraction in vitro
Q38731620	Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma
Q35542014	Phosphatases in cell-matrix adhesion and migration
Q30452661	Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation
Q42807111	Phosphatidylinositol 3-kinase-independent signal transduction pathway for platelet-derived growth factor-induced chemotaxis
Q34135631	Phosphatidylinositol 3-kinases in tumor progression
Q36380062	Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells
Q24300777	Phosphoinositide 3-kinase-mediated activation of cofilin phosphatase Slingshot and its role for insulin-induced membrane protrusion
Q28609603	Phosphoinositide 4- and 5-kinases and the cellular roles of phosphatidylinositol 4,5-bisphosphate
Q43293577	Phosphoinositide-specific phospholipase C in oat roots: association with the actin cytoskeleton
Q89621663	Phosphoinositides Signaling and Epithelial-to-Mesenchymal Transition: Putative Topic for Basic Toxicological Research
Q39850176	Phospholipase C delta 1 is a novel 3p22.3 tumor suppressor involved in cytoskeleton organization, with its epigenetic silencing correlated with high-stage gastric cancer.
Q42828304	Phospholipase C-gamma, protein kinase C and Ca2+/calmodulin-dependent protein kinase II are involved in platelet-derived growth factor-induced phosphorylation of Tiam1.
Q36128605	Phospholipase Cε Modulates Rap1 Activity and the Endothelial Barrier
Q28253553	Phospholipase D
Q35905776	Phosphorylation and Activation of RhoA by ERK in Response to Epidermal Growth Factor Stimulation.
Q42810905	Phosphorylation of WAVE downstream of mitogen-activated protein kinase signaling
Q24682432	Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility
Q28144738	Phosphorylation of collapsin response mediator protein-2 by Rho-kinase. Evidence for two separate signaling pathways for growth cone collapse
Q40915136	Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo
Q28647572	Phosphorylation of non-muscle myosin II regulatory light chain by p21-activated kinase (gamma-PAK)
Q33855713	Phosphorylation of serine 106 in Asef2 regulates cell migration and adhesion turnover
Q42770445	Phosphorylation of the growth arrest-specific protein Gas2 is coupled to actin rearrangements during Go-->G1 transition in NIH 3T3 cells
Q26823650	Phosphorylation-mediated regulation of GEFs for RhoA
Q30453620	Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation
Q24293647	Physical and functional interaction of Fyn tyrosine kinase with a brain-enriched Rho GTPase-activating protein TCGAP
Q24669784	Physical and functional interactions of Galphaq with Rho and its exchange factors
Q37380112	Physical association of the small GTPase Rho with a 68-kDa phosphatidylinositol 4-phosphate 5-kinase in Swiss 3T3 cells.
Q26801831	Physical view on migration modes
Q34233424	Physiological responses to lysophosphatidic acid and related glycero-phospholipids
Q36392528	Physiological role of ROCKs in the cardiovascular system
Q50063741	Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses.
Q73533669	Placement of endothelial cells on the luminal surface of denuded arteries in vitro and in vivo
Q47546216	Placental Basement Membrane Proteins are Required for Effective Cytotrophoblast Invasion in a 3D Bioprinted Placenta Model
Q28285534	Plakophilin 2 couples actomyosin remodeling to desmosomal plaque assembly via RhoA.
Q27317392	Plasticity in the macromolecular-scale causal networks of cell migration
Q72015459	Platelet-derived growth factor (PDGF) receptors in the developing mouse optic pathway
Q41289581	Platelet-derived growth factor (PDGF): actions and mechanisms in vascular smooth muscle
Q71514783	Platelet-derived growth factor-induced formation of tensin and phosphoinositide 3-kinase complexes
Q73378065	Platelet-derived growth factor-stimulated migration of murine fibroblasts is associated with epidermal growth factor receptor expression and tyrosine phosphorylation
Q34294719	Platelets and cancer: a casual or causal relationship: revisited.
Q34287222	Pleckstrin homology domain-mediated activation of the rho-specific guanine nucleotide exchange factor Dbs by Rac1.
Q42830840	Plexin-B semaphorin receptors interact directly with active Rac and regulate the actin cytoskeleton by activating Rho.
Q40349264	Pneumococci induced TLR- and Rac1-dependent NF-kappaB-recruitment to the IL-8 promoter in lung epithelial cells
Q40042108	Polarity-regulating kinase partitioning-defective 1b (PAR1b) phosphorylates guanine nucleotide exchange factor H1 (GEF-H1) to regulate RhoA-dependent actin cytoskeletal reorganization
Q30496884	Polarization and Migration of Hematopoietic Stem and Progenitor Cells Rely on the RhoA/ROCK I Pathway and an Active Reorganization of the Microtubule Network
Q51129061	Polymer fiber-based models of connective tissue repair and healing.
Q42818224	Possible involvement of caspase-like family in maintenance of cytoskeleton integrity
Q50533522	Possible participation of the Rho/Rho-associated coiled-coil-forming kinase pathway in the cell death of Cryptococcus neoformans caused by Staphylococcus aureus adherence.
Q42157075	Post-translational incorporation of the antiproliferative agent azatyrosine into the C-terminus of alpha-tubulin
Q24322164	Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion
Q36946054	Potential applications of biphosphonates in dental surgical implants
Q41710390	Potentiation of cell migration by adhesion-dependent cooperative signals from the GTPase Rac and Raf kinase
Q34494947	Pragmin, a novel effector of Rnd2 GTPase, stimulates RhoA activity.
Q42799520	Prenylation of RhoB is required for its cell transforming function but not its ability to activate serum response element-dependent transcription
Q42833741	Prenylation-dependent association of Ki-Ras with microtubules. Evidence for a role in subcellular trafficking
Q37279611	Prestress and adhesion site dynamics control cell sensitivity to extracellular stiffness
Q34740081	Primary human colonic myofibroblasts are resistant to Clostridium difficile toxin A-induced, but not toxin B-induced, cell death
Q34361140	Process extension and myelin sheet formation in maturing oligodendrocytes
Q48265787	Production of monoclonal antibodies that inhibit ADP-ribosylation of small GTP-binding proteins catalyzed by Clostridium botulinum ADP-ribosyltransferase C3.
Q42400888	Prolyl Hydroxylase Domain (PHD) 2 Affects Cell Migration and F-actin Formation via RhoA/Rho-associated Kinase-dependent Cofilin Phosphorylation
Q30492151	Promigratory and procontractile growth factor environments differentially regulate cell morphogenesis
Q38299021	Promoter region of the transcriptional unit for human alpha 1-chimaerin, a neuron-specific GTPase-activating protein for p21rac
Q41150424	Prostaglandin E receptor EP3 subtype induces neurite retraction via small GTPase Rho.
Q35219865	Prostaglandin E2 and the pathogenesis of pulmonary fibrosis.
Q34043168	Protection after stroke: cellular effectors of neurovascular unit integrity.
Q27315815	Protective effects of the mTOR inhibitor everolimus on cytoskeletal injury in human podocytes are mediated by RhoA signaling
Q41122024	Protein expression changes associated with radiation-induced neoplastic progression of human prostate epithelial cells
Q41083458	Protein isoprenylation in suspension-cultured tobacco cells
Q41063804	Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes
Q34452929	Protein kinase C regulates the recruitment of syndecan-4 into focal contacts
Q28565306	Protein kinase Czeta mediates insulin-induced glucose transport through actin remodeling in L6 muscle cells
Q42746302	Protein kinase c-β-dependent activation of NF-κB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivo.
Q48726985	Protein phosphorylation in response to PDGF stimulation in cultured neurons and astrocytes.
Q33511576	Protein thiol oxidation in murine airway epithelial cells in response to naphthalene or diethyl maleate
Q43576972	Protein transduction: delivery of Tat-GTPase fusion proteins into mammalian cells
Q33905945	Protein transduction: unrestricted delivery into all cells?
Q38352112	Protein-DNA interactions at a drug-responsive element of the human apolipoprotein A-I gene
Q28257295	Proteins regulating Ras and its relatives
Q34010802	Proteomic and phosphoproteomic alterations in benign, premalignant and tumor human breast epithelial cells and xenograft lesions: biomarkers of progression
Q38605514	Pulmonary endothelial cell signaling and function
Q30439157	Pulsatile equibiaxial stretch inhibits thrombin-induced RhoA and NF-kappaB activation
Q42834838	Purification of a lysophosphatidic acid-hydrolysing lysophospholipase from rat brain
Q41969360	Purification of a phosphatidic-acid-hydrolysing phospholipase A2 from rat brain
Q57825385	Quantifying cellular adhesion to extracellular matrix components by single-cell force spectroscopy
Q35271899	Quantitative analysis of F-actin redistribution in astrocytoma cells treated with candidate pharmaceuticals
Q44385309	Quantitative analysis of acyl-lysophosphatidic acid in plasma using negative ionization tandem mass spectrometry
Q23914853	Quantitative changes in cytoskeletal and nuclear actins during cellular transformation
Q28138365	RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion
Q36554758	RAS signalling is abnormal in a c-raf1 MEK1 double mutant
Q37271795	RAS: target for cancer therapy
Q40769254	RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho.
Q28213760	RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho?
Q50437489	RIC8A is essential for the organisation of actin cytoskeleton and cell-matrix interaction.
Q91974300	ROCK Inhibitor-Induced Promotion of Retinal Pigment Epithelial Cell Motility during Wound Healing
Q41954269	ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts
Q41981193	ROCK inhibitor (Y27632) increases apoptosis and disrupts the actin cortical mat in embryonic avian corneal epithelium.
Q39542073	ROCK mediates thrombin's endothelial barrier dysfunction
Q36321444	ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles
Q36324827	ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix
Q36382599	ROCK/Cdc42-mediated microglial motility and gliapse formation lead to phagocytosis of degenerating dopaminergic neurons in vivo.
Q46532614	ROCKII Ser1366 phosphorylation reflects the activation status.
Q46280873	ROS Signaling in the Pathogenesis of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS).
Q43147809	RPTPalpha and PTPepsilon signaling via Fyn/Yes and RhoA is essential for zebrafish convergence and extension cell movements during gastrulation
Q55037157	RRAD inhibits aerobic glycolysis, invasion, and migration and is associated with poor prognosis in hepatocellular carcinoma.
Q38613714	Rab5 induces Rac-independent lamellipodia formation and cell migration
Q28646209	Rac GTPase interacts specifically with phosphatidylinositol 3-kinase
Q40789809	Rac GTPase interacts with GAPs and target proteins through multiple effector sites.
Q42828156	Rac and Cdc42 are potent stimulators of E2F-dependent transcription capable of promoting retinoblastoma susceptibility gene product hyperphosphorylation
Q42807716	Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade
Q57903844	Rac and Rho in tune
Q34815289	Rac and rho: the story behind melanocyte dendrite formation
Q40915141	Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior
Q52166799	Rac is required for constitutive macropinocytosis by dendritic cells but does not control its downregulation.
Q41812511	Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin
Q33893806	Rac regulates endothelial morphogenesis and capillary assembly
Q33774823	Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes
Q40759315	Rac regulates vascular endothelial growth factor stimulated motility
Q40021099	Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways
Q33907087	Rac-1 and Raf-1 kinases, components of distinct signaling pathways, activate myotonic dystrophy protein kinase
Q28569794	Rac-GTPase, osteoclast cytoskeleton and bone resorption
Q33523409	Rac1 and Cdc42 are regulators of HRasV12-transformation and angiogenic factors in human fibroblasts
Q38292096	Rac1 and Cdc42 but not RhoA or Rho kinase activities are required for neurite outgrowth induced by the Netrin-1 receptor DCC (deleted in colorectal cancer) in N1E-115 neuroblastoma cells
Q64950759	Rac1 promotes the survival of H9c2 cells during serum deficiency targeting JNK/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways.
Q33397843	Rac1 regulates pancreatic islet morphogenesis
Q35095889	RacB regulates cytoskeletal function in Dictyostelium spp.
Q28273026	Rad, a novel Ras-related GTPase, interacts with skeletal muscle beta-tropomyosin
Q92581853	Rap1 regulates hepatic stellate cell migration through the modulation of RhoA activity in response to TGF‑β1
Q35683204	Rap1-Rac1 circuits potentiate platelet activation
Q48135404	Rapid and dynamic arginylation of the leading edge β- actin is required for cell migration.
Q51395416	Rapid dendritic remodeling in the developing retina: dependence on neurotransmission and reciprocal regulation by Rac and Rho.
Q42242739	Rapid desensitization and resensitization of bombesin-stimulated phospholipase D activity in Swiss 3T3 cells
Q73747075	Rapid lamellipodia formation in nerve growth factor-stimulated PC12 cells is dependent on Rac and PI3K activity
Q43747327	Rapid morphological changes in astrocytes are accompanied by redistribution but not by quantitative changes of cytoskeletal proteins.
Q37358903	Rapid parallel flow cytometry assays of active GTPases using effector beads
Q91924941	Ras associated with diabetes may play a role in fracture nonunion development in rats
Q34625170	Ras family GTPases control growth of astrocyte processes
Q42829231	Ras mediates the activation of phospholipase D by v-Src
Q42799689	Ras oncoprotein induces CD44 cleavage through phosphoinositide 3-OH kinase and the rho family of small G proteins
Q46594403	Ras proteins increase Ca(2+)-responsiveness of smooth muscle contraction
Q30176086	Ras-GAP controls Rho-mediated cytoskeletal reorganization through its SH3 domain
Q30175349	Ras-GTPase activating protein inhibition specifically induces apoptosis of tumour cells
Q31523965	Ras-related GTPase Rhob represses NF-kappaB signaling
Q37070703	Ras-related associated with diabetes gene acts as a suppressor and inhibits Warburg effect in hepatocellular carcinoma
Q36639126	Real-time imaging reveals that noninvasive mammary epithelial acini can contain motile cells
Q43878348	Rearrangement of the cytoskeletal network induced by platelet-derived growth factor in rat hepatic stellate cells: role of different intracellular signalling pathways
Q92282190	Recent advances in cerebral cavernous malformation research
Q27009359	Recent progress in the study of methylated tumor suppressor genes in gastric cancer
Q49853226	Reciprocal regulation of YAP/TAZ by the Hippo pathway and the Small GTPase pathway.
Q33690103	Redox control of vascular smooth muscle migration
Q36451514	Redox regulation of Rac1 by thiol oxidation.
Q35738096	Redox signaling at invasive microdomains in cancer cells.
Q41151255	Reduced cell attachment and phosphorylation of focal adhesion kinase associated with expression of a mutant insulin receptor
Q39790972	Reduction of renal mass is lethal in mice lacking vimentin. Role of endothelin-nitric oxide imbalance
Q35132831	Redundant mechanisms for stable cell locomotion revealed by minimal models
Q55476721	Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins.
Q24678943	Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation
Q42663964	Regulation by afadin of cyclical activation and inactivation of Rap1, Rac1, and RhoA small G proteins at leading edges of moving NIH3T3 cells.
Q24671083	Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway
Q28592539	Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein
Q37828684	Regulation of Cytoskeleton and Cell Adhesions by the Small GTPase Rho and Its Targets.
Q28215911	Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase
Q38308746	Regulation of MKL1 via actin cytoskeleton dynamics drives adipocyte differentiation
Q48234225	Regulation of RhoA by STAT3 coordinates glial scar formation.
Q33847070	Regulation of Rnd3 localization and function by protein kinase C alpha-mediated phosphorylation
Q43732521	Regulation of Schwann cell morphology and adhesion by receptor-mediated lysophosphatidic acid signaling.
Q48000569	Regulation of TNF-alpha-induced reorganization of the actin cytoskeleton and cell-cell junctions by Rho, Rac, and Cdc42 in human endothelial cells
Q22254209	Regulation of Tiam1 nucleotide exchange activity by pleckstrin domain binding ligands
Q44203321	Regulation of Xenopus embryonic cell adhesion by the small GTPase, rac.
Q37542009	Regulation of actin cytoskeleton dynamics in cells
Q40565418	Regulation of anoikis by Cdc42 and Rac1.
Q36834868	Regulation of cadherin function by Rho and Rac: modulation by junction maturation and cellular context.
Q33744913	Regulation of cadherin-mediated cell-cell adhesion by the Rho family GTPases.
Q24652254	Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts
Q41075647	Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells
Q36382423	Regulation of cortical actin cytoskeleton assembly during polarized cell growth in budding yeast
Q35605754	Regulation of cortical actin networks in cell migration.
Q36233026	Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI).
Q42445511	Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42.
Q36700144	Regulation of dimorphism in Saccharomyces cerevisiae: involvement of the novel protein kinase homolog Elm1p and protein phosphatase 2A
Q35058912	Regulation of endocytic traffic by Rho GTPases.
Q64382600	Regulation of endothelial cell adhesion by profilin
Q41455034	Regulation of endothelin-1- and lysophosphatidic acid-stimulated tyrosine phosphorylation of focal adhesion kinase (pp125fak) in Rat-1 fibroblasts
Q40341780	Regulation of epithelial tubule formation by Rho family GTPases
Q30486408	Regulation of focal adhesion turnover by ErbB signalling in invasive breast cancer cells
Q35077234	Regulation of gene expression by the small GTPase Rho through the ERK6 (p38 gamma) MAP kinase pathway.
Q35087186	Regulation of growth cone actin dynamics by ADF/cofilin
Q41881846	Regulation of interleukin 1 signalling through integrin binding and actin reorganization: disparate effects on NF-kappaB and stress kinase pathways.
Q36254808	Regulation of keratin and integrin gene expression in cancer and drug resistance
Q42825589	Regulation of lysophosphatidic acid-stimulated tyrosine phosphorylation of mitogen-activated protein kinase by protein kinase C- and pertussis toxin-dependent pathways in the endothelial cell line EAhy 926.
Q81739907	Regulation of membrane trafficking, cytoskeleton dynamics, and cell polarity by ROP/RAC GTPases
Q42806934	Regulation of microtubule dynamics in 3T3 fibroblasts by Rho family GTPases
Q42547126	Regulation of neurotrophin-induced axonal responses via Rho GTPases
Q22254735	Regulation of neutrophil adhesion by pituitary growth hormone accompanies tyrosine phosphorylation of Jak2, p125FAK, and paxillin
Q47985876	Regulation of phospholipase C-delta by GTP-binding proteins-rhoA as an inhibitory modulator
Q33698777	Regulation of phospholipase D.
Q40021756	Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells
Q37649264	Regulation of smooth muscle contraction by small GTPases
Q35573994	Regulation of the Actin Cytoskeleton by PI(4,5)P2 and PI(3,4,5)P3
Q30777797	Regulation of the Cool/Pix proteins: key binding partners of the Cdc42/Rac targets, the p21-activated kinases
Q40853476	Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components
Q36909557	Regulation of the actin cytoskeleton by thrombin in human endothelial cells: role of Rho proteins in endothelial barrier function
Q41052407	Regulation of the association of adducin with actin filaments by Rho-associated kinase (Rho-kinase) and myosin phosphatase
Q35678796	Regulation of the cellular content of the organic osmolyte taurine in mammalian cells
Q38196358	Regulation of the endothelial barrier function: a filum granum of cellular forces, Rho-GTPase signaling and microenvironment.
Q42830999	Regulation of the neurofibromatosis type 2 tumor suppressor protein, merlin, by adhesion and growth arrest stimuli
Q34284892	Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42
Q29620156	Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
Q35679329	Relaxin regulates myofibroblast contractility and protects against lung fibrosis
Q36255975	Release of cAMP gating by the alpha6beta4 integrin stimulates lamellae formation and the chemotactic migration of invasive carcinoma cells
Q36920224	Remodeling of the actin cytoskeleton is coordinately regulated by protein kinase C and the ADP-ribosylation factor nucleotide exchange factor ARNO.
Q34764253	Reorganization of actin cytoskeleton by the phosphoinositide metabolite glycerophosphoinositol 4-phosphate
Q52220356	Repair of excisional wounds in the embryo.
Q38325656	Replacement of threonine 558, a critical site of phosphorylation of moesin in vivo, with aspartate activates F-actin binding of moesin. Regulation by conformational change
Q33557956	Requirement for formin-induced actin polymerization during spread of Shigella flexneri
Q34435975	Requirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase
Q37295867	Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior
Q40749495	Requirement of Rho-family GTPases in the invasion of Type 1-piliated uropathogenic Escherichia coli
Q42834090	Requirement of cortical actin organization for bombesin, endothelin, and EGF receptor internalization
Q54570559	Residues of the Rho family GTPases Rho and Cdc42 that specify sensitivity to Dbl-like guanine nucleotide exchange factors.
Q39941899	Resistance of tumor cells to cytolytic T lymphocytes involves Rho-GTPases and focal adhesion kinase activation.
Q28476529	Responses of human endothelial cells to pathogenic and non-pathogenic Leptospira species
Q30464665	Responses to sphingosine-1-phosphate in X. laevis oocytes: similarities with lysophosphatidic acid signaling
Q35694895	Retracted: Cell-Substrate Interactions Feedback to Direct Cell Migration along or against Morphological Polarization
Q28728770	Retracted: EGFR Inhibition in Glioma Cells Modulates Rho Signaling to Inhibit Cell Motility and Invasion and Cooperates with Temozolomide to Reduce Cell Growth
Q36360393	Reversal of the Ras-induced transformed phenotype by HR12, a novel ras farnesylation inhibitor, is mediated by the Mek/Erk pathway
Q57032072	Reversible self-assembly of superstructured networks
Q37378764	Rheostatic signaling by CD44 and hyaluronan
Q55395574	Rho A Regulates Epidermal Growth Factor-Induced Human Osteosarcoma MG63 Cell Migration.
Q33292549	Rho Family GTPases Bind to Phosphoinositide Kinases
Q30375572	Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure.
Q56912219	Rho GTPase activity modulates paramyxovirus fusion protein-mediated cell–cell fusion
Q35567822	Rho GTPase controls Drosophila salivary gland lumen size through regulation of the actin cytoskeleton and Moesin
Q36021522	Rho GTPase function in flies: insights from a developmental and organismal perspective
Q38284409	Rho GTPase isoforms in cell motility: Don't fret, we have FRET.
Q42148645	Rho GTPase protein expression and activation in murine monocytes/macrophages is not modulated by model biomaterial surfaces in serum-containing in vitro cultures
Q39861745	Rho GTPase signaling and PTH 3-34, but not PTH 1-34, maintain the actin cytoskeleton and antagonize bisphosphonate effects in mouse osteoblastic MC3T3-E1 cells.
Q34612747	Rho GTPase signalling pathways in the morphological changes associated with apoptosis.
Q36903028	Rho GTPase-activating bacterial toxins: from bacterial virulence regulation to eukaryotic cell biology
Q34225958	Rho GTPase-dependent transformation by G protein-coupled receptors
Q73089693	Rho GTPases and cell migration-fibroblast wound healing
Q40848188	Rho GTPases and cell migration: measurement of macrophage chemotaxis
Q35923917	Rho GTPases and leucocyte-induced endothelial remodelling
Q40623088	Rho GTPases and phosphoinositide 3-kinase organize formation of branched dendrites
Q37122081	Rho GTPases and regulation of hematopoietic stem cell localization
Q35064607	Rho GTPases and spermatogenesis.
Q35127959	Rho GTPases and the regulation of endothelial permeability
Q29547740	Rho GTPases and their effector proteins
Q42853149	Rho GTPases at the crossroad of signaling networks in mammals
Q27009021	Rho GTPases at the crossroad of signaling networks in mammals: impact of Rho-GTPases on microtubule organization and dynamics
Q42642979	Rho GTPases central regulators of cell migration
Q40918897	Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes
Q29614244	Rho GTPases control polarity, protrusion, and adhesion during cell movement
Q38151855	Rho GTPases control specific cytoskeleton-dependent functions of hematopoietic stem cells
Q39984874	Rho GTPases in PC-3 prostate cancer cell morphology, invasion and tumor cell diapedesis
Q39241843	Rho GTPases in ameloblast differentiation
Q38050708	Rho GTPases in animal cell cytokinesis: an occupation by the one percent
Q27860969	Rho GTPases in cell biology
Q36147929	Rho GTPases in embryonic development
Q37471296	Rho GTPases in hematopoietic stem cell functions
Q50482816	Rho GTPases in mammalian spinal neural tube closure.
Q38119740	Rho GTPases in neurodegeneration diseases
Q29620432	Rho GTPases in neuronal morphogenesis
Q38005048	Rho GTPases in primary brain tumor malignancy and invasion
Q92816177	Rho GTPases in the Physiology and Pathophysiology of Peripheral Sensory Neurons
Q34554757	Rho GTPases in transformation and metastasis.
Q26865752	Rho GTPases, phosphoinositides, and actin: a tripartite framework for efficient vesicular trafficking
Q38933808	Rho GTPases, their post-translational modifications, disease-associated mutations and pharmacological inhibitors
Q64935603	Rho GTPases-Emerging Regulators of Glucose Homeostasis and Metabolic Health.
Q26782005	Rho GTPases: Novel Players in the Regulation of the DNA Damage Response?
Q38224569	Rho GTPases: masters of cell migration
Q34112824	Rho GTPases: molecular switches that control the organization and dynamics of the actin cytoskeleton
Q40119156	Rho activation regulates CXCL12 chemokine stimulated actin rearrangement and restitution in model intestinal epithelia.
Q36603820	Rho activity critically and selectively regulates endothelial cell organization during angiogenesis
Q38613114	Rho and Rab small G proteins coordinately reorganize stress fibers and focal adhesions in MDCK cells
Q28645748	Rho and Rac take center stage
Q40403027	Rho as a regulator of the cytoskeleton.
Q43651093	Rho directs activation-associated changes in rat hepatic stellate cell morphology via regulation of the actin cytoskeleton
Q41554078	Rho effectors and reorganization of actin cytoskeleton
Q42813751	Rho family GTP binding proteins are involved in the regulatory volume decrease process in NIH3T3 mouse fibroblasts
Q41353297	Rho family GTP-binding proteins in growth cone signalling
Q41873543	Rho family GTPase Cdc42 is essential for the actin-based motility of Shigella in mammalian cells.
Q48547144	Rho family GTPase inhibition reveals opposing effects of mitogen-activated protein kinase kinase/extracellular signal-regulated kinase and Janus kinase/signal transducer and activator of transcription signaling cascades on neuronal survival.
Q36565713	Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid
Q38283635	Rho family GTPases: making it to the third dimension
Q34040276	Rho family GTPases: more than simple switches
Q33959704	Rho family proteins in cell adhesion and cell migration.
Q93064569	Rho guanine nucleotide exchange factor ARHGEF10 is a putative tumor suppressor in pancreatic ductal adenocarcinoma
Q36255290	Rho guanosine triphosphatase mediates the selective stabilization of microtubules induced by lysophosphatidic acid
Q40588907	Rho is involved in superoxide formation during phagocytosis of opsonized zymosans
Q41091270	Rho is required for the initiation of calcium signaling and phagocytosis by Fcgamma receptors in macrophages
Q42797891	Rho kinase inhibition initiates apoptosis in human airway epithelial cells
Q30660037	Rho kinase regulates the intracellular micromechanical response of adherent cells to rho activation
Q39979816	Rho kinases regulate corneal epithelial wound healing
Q28505019	Rho localization in cells and tissues
Q44859639	Rho modulates hepatic sinusoidal endothelial fenestrae via regulation of the actin cytoskeleton in rat endothelial cells
Q40162264	Rho plays a central role in regulating local cell-matrix mechanical interactions in 3D culture
Q73274249	Rho plays an important role in angiotensin II-induced hypertrophic responses in cardiac myocytes
Q41077461	Rho prevents apoptosis through Bcl-2 expression: implications for interleukin-2 receptor signal transduction
Q37933751	Rho protein crosstalk: another social network?
Q24563849	Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia
Q51972760	Rho proteins and the cellular mechanisms of mental retardation.
Q37369834	Rho proteins play a critical role in cell migration during the early phase of mucosal restitution
Q35974513	Rho proteins, mental retardation and the neurobiological basis of intelligence
Q46900605	Rho signaling in Entamoeba histolytica modulates actomyosin-dependent activities stimulated during invasive behavior
Q64884251	Rho signaling research: history, current status and future directions.
Q41184119	Rho small GTPase regulates the stability of individual focal adhesions: a FRET-based visualization of GDP/GTP exchange on small GTPases
Q42796333	Rho- and rac-dependent assembly of focal adhesion complexes and actin filaments in permeabilized fibroblasts: an essential role for ezrin/radixin/moesin proteins
Q28295444	Rho-associated kinase of chicken gizzard smooth muscle
Q29614250	Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho
Q37786442	Rho-associated kinase-dependent contraction of stress fibres and the organization of focal adhesions
Q52096698	Rho-dependent contractile responses in the neuronal growth cone are independent of classical peripheral retrograde actin flow.
Q41075099	Rho-dependent membrane folding causes Shigella entry into epithelial cells
Q38612581	Rho-dependent regulation of cell spreading by the tetraspan membrane protein Gas3/PMP22.
Q37891679	Rho-guanine nucleotide exchange factors during development: Force is nothing without control
Q44107653	Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells
Q40126648	Rho-kinase dependent organization of stress fibers and focal adhesions in cultured fibroblasts.
Q24678197	Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association
Q28609762	Rho-kinase--mediated contraction of isolated stress fibers
Q33829589	Rho-like GTPases: their role in epithelial cell-cell adhesion and invasion
Q73534478	Rho-like GTPases: their role in epithelial cell-cell adhesion and invasion
Q36289136	Rho-mediated contractility exposes a cryptic site in fibronectin and induces fibronectin matrix assembly.
Q35681634	Rho-regulatory proteins in breast cancer cell motility and invasion
Q40525077	Rho-related proteins: actin cytoskeleton and cell cycle
Q36945360	Rho-stimulated contractility contributes to the fibroblastic phenotype of Ras-transformed epithelial cells
Q24671788	Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
Q42823179	Rho/ROCK pathway contributes to the activation of extracellular signal-regulated kinase/GATA-4 during myocardial cell hypertrophy
Q24306817	Rho/Rhotekin-mediated NF-kappaB activation confers resistance to apoptosis
Q36891609	RhoA GTPase and serum response factor control selectively the expression of MyoD without affecting Myf5 in mouse myoblasts
Q30805064	RhoA GTPase inhibition organizes contraction during epithelial morphogenesis.
Q34869485	RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts
Q36228636	RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to Oxidative Stress
Q45099267	RhoA and Rho-kinase dependent and independent signals mediate TGF-beta-induced pulmonary endothelial cytoskeletal reorganization and permeability
Q34191740	RhoA and lysophosphatidic acid are involved in the actin cytoskeleton reorganization of astrocytes exposed to ethanol
Q36038081	RhoA and resistance artery remodeling.
Q44738584	RhoA and zeta PKC control distinct modalities of LFA-1 activation by chemokines: critical role of LFA-1 affinity triggering in lymphocyte in vivo homing
Q33946704	RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity
Q34171845	RhoA is required for cortical retraction and rigidity during mitotic cell rounding
Q33754914	RhoA signaling is required for respiratory syncytial virus-induced syncytium formation and filamentous virion morphology
Q40977598	RhoA stimulates p27(Kip) degradation through its regulation of cyclin E/CDK2 activity
Q42459171	RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actin
Q45286570	RhoA, RhoB, RhoC, Rac1, Cdc42, and Tc10 mRNA levels in spinal cord, sensory ganglia, and corticospinal tract neurons and long-lasting specific changes following spinal cord injury
Q38814449	RhoA-JNK Regulates the E-Cadherin Junctions of Human Gingival Epithelial Cells
Q39576430	RhoA-binding kinase alpha translocation is facilitated by the collapse of the vimentin intermediate filament network
Q38610718	RhoA-dependent phosphorylation and relocalization of ERM proteins into apical membrane/actin protrusions in fibroblasts
Q33948290	RhoA-dependent switch between alpha2beta1 and alpha3beta1 integrins is induced by laminin-5 during early stage of HT-29 cell differentiation
Q40530623	RhoA/ROCK and Cdc42 regulate cell-cell contact and N-cadherin protein level during neurodetermination of P19 embryonal stem cells
Q50477773	RhoA/ROCK pathway activity is essential for the correct localization of the germ plasm mRNAs in zebrafish embryos.
Q39525711	RhoA/ROCK signaling mediates plasticity of scirrhous gastric carcinoma motility
Q37586828	RhoA/Rho-kinase signaling: a therapeutic target in pulmonary hypertension
Q39795061	RhoB enhances migration and MMP1 expression of prostate cancer DU145.
Q38740120	RhoB/ROCK mediates oxygen-glucose deprivation-stimulated syncytiotrophoblast microparticle shedding in preeclampsia
Q28284154	RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility
Q34785853	RhoC GTPase overexpression modulates induction of angiogenic factors in breast cells
Q34387577	RhoC impacts the metastatic potential and abundance of breast cancer stem cells
Q87079470	RhoC involved in the migration of neural stem/progenitor cells
Q36285714	RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells
Q24675619	RhoE binds to ROCK I and inhibits downstream signaling
Q40445505	RhoE function is regulated by ROCK I-mediated phosphorylation
Q39961437	RhoE inhibits cell cycle progression and Ras-induced transformation
Q57362549	RhoE participates in the stimulation of the inflammatory response induced by ethanol in astrocytes
Q39575625	RhoE regulates actin cytoskeleton organization and cell migration.
Q24651374	RhoG GTPase controls a pathway that independently activates Rac1 and Cdc42Hs
Q24310745	RhoG signals in parallel with Rac1 and Cdc42
Q28298035	RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG
Q24314694	RhoGDIgamma: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas
Q35536339	RhoGDIβ Inhibits Bone Morphogenetic Protein 4 (BMP4)-induced Adipocyte Lineage Commitment and Favors Smooth Muscle-like Cell Differentiation
Q30274944	RhoGTPase Regulators Orchestrate Distinct Stages of Synaptic Development
Q26998892	RhoGTPases as key players in mammalian cell adaptation to microgravity
Q37319461	RhoGTPases, actomyosin signaling and regulation of the epithelial Apical Junctional Complex
Q33917875	RhoJ is an endothelial cell-restricted Rho GTPase that mediates vascular morphogenesis and is regulated by the transcription factor ERG.
Q47975846	RhoN, a novel small GTP-binding protein expressed predominantly in neurons and hepatic stellate cells.
Q28281838	Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain
Q28184673	Rnd proteins function as RhoA antagonists by activating p190 RhoGAP
Q51792249	Rock 'n' Rho: regulation of ion channels.
Q39917168	Role for EPS8 in squamous carcinogenesis.
Q116166336	Role of ARP2/3 Complex-Driven Actin Polymerization in RSV Infection
Q37386165	Role of Dictyostelium racE in cytokinesis: mutational analysis and localization studies by use of green fluorescent protein
Q41133967	Role of Rho family proteins in phospholipase D activation by growth factors
Q46717620	Role of Rho proteins in carbachol-induced contractions in intact and permeabilized guinea-pig intestinal smooth muscle
Q46592184	Role of Rho-kinase in reexpansion pulmonary edema in rabbits
Q40937431	Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line
Q28257507	Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition
Q37044604	Role of TGF-β and the tumor microenvironment during mammary tumorigenesis
Q46184903	Role of a new Rho family member in cell migration and axon guidance in C. elegans
Q42278235	Role of actin polymerization and adhesion to extracellular matrix in Rac- and Rho-induced cytoskeletal reorganization
Q28510007	Role of citron kinase in dendritic morphogenesis of cortical neurons
Q74539453	Role of endothelin B receptor signals in reactive astrocytes
Q30453921	Role of guanine nucleotide-binding proteins--ras-family or trimeric proteins or both--in Ca2+ sensitization of smooth muscle
Q35084782	Role of integrins in cell invasion and migration
Q24685940	Role of p120 Ras-GAP in directed cell movement
Q28238120	Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras
Q39460820	Role of phosphoinositide 3-kinase in the aggressive tumor growth of HT1080 human fibrosarcoma cells
Q34466061	Role of plasma membrane lipid microdomains in respiratory syncytial virus filament formation
Q40653322	Role of protein kinase C isoforms in rat epididymal microvascular endothelial barrier function
Q77451328	Role of rho proteins in agonist regulation of phospholipase D in HL-60 cells
Q37140970	Role of small GTPase Rho in regulating corneal epithelial wound healing
Q33214585	Role of small GTPases in Trypanosoma cruzi invasion in MDCK cell lines
Q37428863	Role of stress fibers and focal adhesions as a mediator for mechano-signal transduction in endothelial cells in situ
Q36366957	Role of the PI3K regulatory subunit in the control of actin organization and cell migration
Q42828877	Role of the p70(S6K) pathway in regulating the actin cytoskeleton and cell migration
Q28364936	Role of transglutaminase II in retinoic acid-induced activation of RhoA-associated kinase-2
Q35041690	Roles of atypical protein kinase C in lysophosphatidic acid-induced type II adenylyl cyclase activation in RAW 264.7 macrophages
Q42108230	Roles of the small GTPases RhoA and Rac1 in cell behavior
Q36379985	Rop GTPase-dependent dynamics of tip-localized F-actin controls tip growth in pollen tubes
Q30531499	Rotational motion during three-dimensional morphogenesis of mammary epithelial acini relates to laminin matrix assembly
Q24304219	Rudhira/BCAS3 is a cytoskeletal protein that controls Cdc42 activation and directional cell migration during angiogenesis
Q42004714	Rundown of somatodendritic N-methyl-D-aspartate (NMDA) receptor channels in rat hippocampal neurones: evidence for a role of the small GTPase RhoA
Q37012349	SEC14 and spectrin domains 1 (Sestd1) and Dapper antagonist of catenin 1 (Dact1) scaffold proteins cooperatively regulate the Van Gogh-like 2 (Vangl2) four-pass transmembrane protein and planar cell polarity (PCP) pathway during embryonic developmen
Q28508471	SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility
Q34562147	SPARC fusion protein induces cellular adhesive signaling
Q24312871	SPIN90-IRSp53 complex participates in Rac-induced membrane ruffling
Q28512614	STARS, a striated muscle activator of Rho signaling and serum response factor-dependent transcription
Q35084574	Salmonella Interaction with and Passage through the Intestinal Mucosa: Through the Lens of the Organism
Q36445367	Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective.
Q28293934	Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex
Q41062796	Scatter factor induces segregation of multinuclear cells into several discrete motile domains
Q29547308	Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
Q34672405	Selective alterations in biosynthetic and endocytic protein traffic in Madin-Darby canine kidney epithelial cells expressing mutants of the small GTPase Rac1.
Q41215445	Selective up-regulation of alpha 1-chimaerin mRNA in SK-N-SH neuroblastoma cells by K+/-induced depolarisation
Q30836760	Semaphorin 3A Increases FAK Phosphorylation at Focal Adhesions to Modulate MDA-MB-231 Cell Migration and Spreading on Different Substratum Concentrations
Q24307909	Semaphorin 5A and plexin-B3 regulate human glioma cell motility and morphology through Rac1 and the actin cytoskeleton
Q81462678	Senescence-associated alterations of cytoskeleton: extraordinary production of vimentin that anchors cytoplasmic p53 in senescent human fibroblasts
Q34594621	Sensing the environment: a historical perspective on integrin signal transduction
Q42828807	Sensitivity of wild type and mutant ras alleles to Ras specific exchange factors: Identification of factor specific requirements
Q34582276	Sensor potency of the moonlighting enzyme-decorated cytoskeleton: the cytoskeleton as a metabolic sensor
Q34300408	Sequencing and analysis of the gene encoding the alpha-toxin of Clostridium novyi proves its homology to toxins A and B of Clostridium difficile
Q34242704	Ser1333 phosphorylation indicates ROCKI activation
Q42918539	Serum response factor is crucial for actin cytoskeletal organization and focal adhesion assembly in embryonic stem cells
Q55354238	Serum starvation improves transient transfection efficiency in differentiating embryonic stem cells.
Q41063510	Serum-induced membrane depolarization in quiescent fibroblasts: activation of a chloride conductance through the G protein-coupled LPA receptor
Q36959935	Serum-induced phosphorylation of the serum response factor coactivator MKL1 by the extracellular signal-regulated kinase 1/2 pathway inhibits its nuclear localization
Q36234582	Serum-induced signal transduction determines the peripheral location of beta-actin mRNA within the cell
Q34200186	Shk1, a homolog of the Saccharomyces cerevisiae Ste20 and mammalian p65PAK protein kinases, is a component of a Ras/Cdc42 signaling module in the fission yeast Schizosaccharomyces pombe
Q40500421	Signal transduction by the antigen receptors of B and T lymphocytes.
Q41500587	Signal transduction for PDGF-induced chemotaxis of vascular smooth muscle cells
Q28201752	Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway
Q42805134	Signal transduction pathways involving the small G proteins rac and Cdc42 and phosphoinositide kinases.
Q40792108	Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase
Q28609164	Signal transduction via platelet-derived growth factor receptors
Q26849280	Signaling networks of Rho GTPases in cell motility
Q40868085	Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets
Q40498880	Signalling Pathways Controlling Cellular Actin Organization
Q42827718	Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.
Q39444795	Signals from the Ras, Rac, and Rho GTPases converge on the Pak protein kinase in Rat-1 fibroblasts
Q51542671	Simultaneous covalent and noncovalent hybrid polymerizations.
Q35774325	Single somatic ras gene point mutation in soft tissue malignant fibrous histiocytomas
Q93892589	Skeleton crew
Q30480418	Slit and Netrin-1 guide cranial motor axon pathfinding via Rho-kinase, myosin light chain kinase and myosin II.
Q34057932	Small G-protein networks: their crosstalk and signal cascades.
Q34012566	Small GTP binding proteins and bacterial virulence
Q74230894	Small GTP-binding protein Rho stimulates the actomyosin system, leading to invasion of tumor cells
Q46872966	Small GTP-binding protein RhoB is expressed in glial Müller cells in the vertebrate retina.
Q24530193	Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes.
Q43603044	Small GTP-binding protein, Rho, both increased and decreased cellular motility, activation of matrix metalloproteinase 2 and invasion of human osteosarcoma cells
Q37109688	Small GTP-binding proteins and their regulators in cardiac hypertrophy
Q47967575	Small GTPase RhoD suppresses cell migration and cytokinesis.
Q24551209	Small GTPase RhoG is a key regulator for neurite outgrowth in PC12 cells
Q36877317	Small GTPases and LFA-1 reciprocally modulate adhesion and signaling
Q64259857	Small GTPases and Their Role in Vascular Disease
Q33723093	Small GTPases in lymphocyte biology: Rho proteins take center stage
Q55386096	Small Rho GTPases and the Effector VipA Mediate the Invasion of Epithelial Cells by Filamentous Legionella pneumophila.
Q30533280	Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility
Q44599675	Smooth muscle F-actin disassembly and RhoA/Rho-kinase signaling during endotoxin-induced alterations in pulmonary arterial compliance.
Q30618659	Smooth muscle specific Rac1 deficiency induces hypertension by preventing p116RIP3-dependent RhoA inhibition
Q24537280	Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers.
Q24533574	Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation
Q42808195	Somatic RHOA mutation in angioimmunoblastic T cell lymphoma.
Q40727776	Somatostatin, acting at receptor subtype 1, inhibits Rho activity, the assembly of actin stress fibers, and cell migration.
Q33335734	SopE and SopE2 from Salmonella typhimurium activate different sets of RhoGTPases of the host cell
Q33923635	Sorting of tropomyosin isoforms in synchronised NIH 3T3 fibroblasts: evidence for distinct microfilament populations
Q30498093	Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53
Q36015668	Spatio-temporal regulation of Rac1 localization and lamellipodia dynamics during epithelial cell-cell adhesion
Q33991299	Specific behavior of intracellular Streptococcus pyogenes that has undergone autophagic degradation is associated with bacterial streptolysin O and host small G proteins Rab5 and Rab7
Q24554294	Specification of actin filament function and molecular composition by tropomyosin isoforms
Q40068834	Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases.
Q27652343	Specificity of Interactions between mDia Isoforms and Rho Proteins
Q42800311	Sphingosine 1-phosphate stimulates rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 fibroblasts
Q41065014	Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor
Q42823528	Sphingosylphosphorylcholine rapidly induces tyrosine phosphorylation of p125FAK and paxillin, rearrangement of the actin cytoskeleton and focal contact assembly. Requirement of p21rho in the signaling pathway
Q28574428	Splicing isoforms of rat Ash/Grb2. Isolation and characterization of the cDNA and genomic DNA clones and implications for the physiological roles of the isoforms
Q35224159	Spreading of differentiating human monocytes is associated with a major increase in membrane-bound CDC42.
Q34520122	Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors
Q71343407	Src, ras, and rac mediate the migratory response elicited by NGF and PMA in PC12 cells
Q36908368	Stability of adhesion clusters and cell reorientation under lateral cyclic tension
Q42806200	Stability of p21Waf1/Cip1 CDK inhibitor protein is responsive to RhoA-mediated regulation of the actin cytoskeleton.
Q36236197	Stable, detyrosinated microtubules function to localize vimentin intermediate filaments in fibroblasts
Q57910036	Stimulation of actin stress fibre formation mediated by activation of phospholipase D
Q24683694	Stress fibers are generated by two distinct actin assembly mechanisms in motile cells
Q40974745	Stress fibers, autophagy and necrosis by persistent exposure to PM2.5 from biomass combustion
Q33889582	Stress-activated protein kinases are negatively regulated by cell density.
Q30514032	Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators
Q41050673	Stringent structural requirements for anti-Ras activity of S-prenyl analogues
Q39673753	Stromal cell-derived factor 1alpha activates LIM kinase 1 and induces cofilin phosphorylation for T-cell chemotaxis
Q36256190	Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases
Q28257299	Structural determinants required for the interaction between Rho GTPase and the GTPase-activating domain of p190
Q27704759	Structural evidence of the species-dependent albumin binding of the modified cyclic phosphatidic acid with cytotoxic properties
Q28646548	Structural requirements for PAK activation by Rac GTPases
Q33613391	Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors
Q27766337	Structure and mutagenesis of the Dbl homology domain
Q27660409	Structure of Shigella IpgB2 in Complex with Human RhoA: IMPLICATIONS FOR THE MECHANISM OF BACTERIAL GUANINE NUCLEOTIDE EXCHANGE FACTOR MIMICRY
Q48104351	Structure, expression, and phylogenetic relationships of a family of ypt genes encoding small G-proteins in the green alga Volvox carteri
Q30944794	Study of in situ function of cytoskeletal proteins in lamellipodia and filopodia using microscale chromophore-assisted laser inactivation
Q41287836	Subcellular distribution of small GTP-binding proteins in the intestinal cell line Caco-2.
Q48486763	Subcellular localization, expression patterns, SNPs and association analyses of the porcine HUMMLC2B gene.
Q37416528	Substrate stiffness regulates solubility of cellular vimentin
Q36542078	Supervised membrane swimming: small G-protein lifeguards regulate PIPK signalling and monitor intracellular PtdIns(4,5)P2 pools.
Q40890934	Suppression of malignant growth potentials of v-Src-transformed human gallbladder epithelial cells by adenovirus-mediated dominant negative H-Ras
Q42085008	Suppression of vinculin expression by antisense transfection confers changes in cell morphology, motility, and anchorage-dependent growth of 3T3 cells.
Q35828663	Surface-enhanced Raman scattering detection of lysophosphatidic acid
Q100761811	Synaptic vesicle traffic is supported by transient actin filaments and regulated by PKA and NO
Q36236564	Syndecan-1 mediates cell spreading in transfected human lymphoblastoid (Raji) cells
Q40080188	Syndecans promote integrin-mediated adhesion of mesenchymal cells in two distinct pathways.
Q40953022	Synergism among lysophosphatidic acid, beta1A integrins, and epidermal growth factor or platelet-derived growth factor in mediation of cell migration
Q29620454	Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae
Q37061519	TEM4 is a junctional Rho GEF required for cell-cell adhesion, monolayer integrity and barrier function
Q29616456	TGF-beta and epithelial-to-mesenchymal transitions
Q40663059	TGF-beta1-mediated alterations of renal proximal tubular epithelial cell phenotype
Q24322063	TIM, a Dbl-related protein, regulates cell shape and cytoskeletal organization in a Rho-dependent manner
Q37286256	TLR4-Activated MAPK-IL-6 Axis Regulates Vascular Smooth Muscle Cell Function
Q30739769	TNF-alpha induces actin cytoskeleton reorganization in glomerular epithelial cells involving tyrosine phosphorylation of paxillin and focal adhesion kinase
Q47774080	TNF-α induces dyscohesion of epithelial cells. Association with disassembly of actin filaments
Q30355317	Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity.
Q42653203	Tandem duplication of rab genes followed by sequence divergence and acquisition of distinct functions in Trypanosoma brucei
Q30476548	Targeted ablation of plectin isoform 1 uncovers role of cytolinker proteins in leukocyte recruitment
Q27028075	Targeting Cdc42 in cancer
Q47984457	Targeting cancer cell integrins using gold nanorods in photothermal therapy inhibits migration through affecting cytoskeletal proteins
Q35892052	Targeting of host-cell ubiquitin and ubiquitin-like pathways by bacterial factors
Q44814601	Temporal dissection of beta1-integrin signaling indicates a role for p130Cas-Crk in filopodia formation
Q38239651	Tenascin-C and mechanotransduction in the development and diseases of cardiovascular system
Q27027610	Tenascin-C in development and disease of blood vessels
Q36328754	Tenascin-C suppresses Rho activation
Q34250775	Tension is required but not sufficient for focal adhesion maturation without a stress fiber template
Q36234770	Tetraspanin CD151 stimulates adhesion-dependent activation of Ras, Rac, and Cdc42 by facilitating molecular association between β1 integrins and small GTPases
Q36083442	Tgf-beta superfamily and mouse craniofacial development: interplay of morphogenetic proteins and receptor signaling controls normal formation of the face.
Q42812980	The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.
Q30480147	The Abl-related gene tyrosine kinase acts through p190RhoGAP to inhibit actomyosin contractility and regulate focal adhesion dynamics upon adhesion to fibronectin
Q55515512	The BH3-only protein BAD mediates TNFα cytotoxicity despite concurrent activation of IKK and NF-κB in septic shock.
Q24554429	The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins
Q28204737	The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway
Q36233735	The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity
Q36821782	The Caenorhabditis elegans p21-activated kinase (CePAK) colocalizes with CeRac1 and CDC42Ce at hypodermal cell boundaries during embryo elongation
Q27308548	The Calponin Family Member CHDP-1 Interacts with Rac/CED-10 to Promote Cell Protrusions
Q54722141	The Cdk inhibitor p57(Kip2) controls LIM-kinase 1 activity and regulates actin cytoskeleton dynamics.
Q35609836	The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation
Q48191911	The Cullin-3-Rbx1-KCTD10 complex controls endothelial barrier function via K63 ubiquitination of RhoB.
Q28288875	The Dbl family of oncogenes
Q34584212	The Dictyostelium Bcr/Abr-related protein DRG regulates both Rac- and Rab-dependent pathways
Q30175160	The Drosophila HEM-2/NAP1 homolog KETTE controls axonal pathfinding and cytoskeletal organization.
Q35203423	The Drosophila Pkn protein kinase is a Rho/Rac effector target required for dorsal closure during embryogenesis
Q35506231	The Drosophila Ral GTPase regulates developmental cell shape changes through the Jun NH(2)-terminal kinase pathway
Q42771059	The Drosophila lethal(2)giant larvae tumor suppressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain
Q36322795	The Drosophila tumor suppressor gene dlg is required for normal synaptic bouton structure
Q41651168	The Eph family in the patterning of neural development
Q42516196	The Epithelial-to-Mesenchymal Transition in Breast Cancer: Focus on Basal-Like Carcinomas
Q37135353	The G protein-coupled estrogen receptor-1, GPER-1, promotes fibrillogenesis via a Shc-dependent pathway resulting in anchorage-independent growth
Q42831845	The G-protein G13 but not G12 mediates signaling from lysophosphatidic acid receptor via epidermal growth factor receptor to Rho.
Q42514518	The GTP-binding protein Rac does not couple PI 3-kinase to insulin-stimulated glucose transport in adipocytes
Q41694762	The GTP-binding protein Rho.
Q35973755	The GTP-binding protein RhoA mediates Na,K-ATPase exocytosis in alveolar epithelial cells
Q29618141	The GTPase dynamin binds to and is activated by a subset of SH3 domains
Q24648605	The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia
Q28660413	The Gβγ-Src signaling pathway regulates TNF-induced necroptosis via control of necrosome translocation
Q40635407	The Haemophilus ducreyi cytolethal distending toxin induces DNA double-strand breaks and promotes ATM-dependent activation of RhoA.
Q33852530	The IL-1 receptor and Rho directly associate to drive cell activation in inflammation
Q41660347	The Impact of Non-Lethal Single-Dose Radiation on Tumor Invasion and Cytoskeletal Properties.
Q35607447	The Interplay between ROS and Ras GTPases: Physiological and Pathological Implications.
Q92082452	The Intrinsic GDP/GTP Exchange Activities of Cdc42 and Rac1 Are Critical Determinants for Their Specific Effects on Mobilization of the Actin Filament System
Q24324355	The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions
Q30441975	The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL).
Q28513273	The Myosin IXb motor activity targets the myosin IXb RhoGAP domain as cargo to sites of actin polymerization.
Q30010182	The N-terminal DH-PH domain of Trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion
Q28609367	The N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium
Q24310756	The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion
Q42498482	The P-Rex1/Rac signaling pathway as a point of convergence for HER/ErbB receptor and GPCR responses
Q44566221	The PI 3-kinase-Rac-p38 MAP kinase pathway is involved in the formation of signet-ring cell carcinoma
Q24646620	The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization
Q28239729	The PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesions
Q47953335	The Rac GTPase in Cancer: From Old Concepts to New Paradigms
Q24316220	The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases
Q40733281	The Ras signal transduction pathway
Q34379884	The Ras-related GTPase Rac1 binds tubulin
Q29614253	The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts
Q26750608	The Regulation of Cellular Responses to Mechanical Cues by Rho GTPases
Q34452174	The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation
Q40273270	The Rho GTPase effector ROCK regulates cyclin A, cyclin D1, and p27Kip1 levels by distinct mechanisms
Q41740176	The Rho effector, PKN, regulates ANF gene transcription in cardiomyocytes through a serum response element
Q42818770	The Rho exchange factor Net1 is regulated by nuclear sequestration
Q39574637	The Rho family G proteins play a critical role in muscle differentiation
Q28292490	The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF
Q36320914	The Rho kinases I and II regulate different aspects of myosin II activity
Q34398250	The Rho-ADP-ribosylating C3 exoenzyme from Clostridium botulinum and related C3-like transferases
Q24320087	The Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migration
Q28200945	The RhoA-binding protein, rhophilin-2, regulates actin cytoskeleton organization
Q37424400	The Role of Ect2 Nuclear RhoGEF Activity in Ovarian Cancer Cell Transformation.
Q38190031	The STARS signaling pathway: a key regulator of skeletal muscle function.
Q42817457	The Salmonella pathogenicity island 1 secretion system directs cellular cholesterol redistribution during mammalian cell entry and intracellular trafficking
Q28216634	The Shb adaptor protein causes Src-dependent cell spreading and activation of focal adhesion kinase in murine brain endothelial cells
Q29042060	The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts
Q34325524	The Sprouty-related protein, Spred, inhibits cell motility, metastasis, and Rho-mediated actin reorganization
Q37048438	The Src homology 3 domain-containing guanine nucleotide exchange factor is overexpressed in high-grade gliomas and promotes tumor necrosis factor-like weak inducer of apoptosis-fibroblast growth factor-inducible 14-induced cell migration and invasio
Q34045066	The Staphylococcus aureus epidermal cell differentiation inhibitor toxin promotes formation of infection foci in a mouse model of bacteremia
Q22254081	The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho
Q36348731	The Vibrio parahaemolyticus effector VopC mediates Cdc42-dependent invasion of cultured cells but is not required for pathogenicity in an animal model of infection
Q41485473	The Yersinia Yops inhibit invasion of Listeria, Shigella and Edwardsiella but not Salmonella into epithelial cells
Q38309336	The actin binding site in the tail domain of Dictyostelium myosin IC (myoC) resides within the glycine- and proline-rich sequence (tail homology region 2).
Q44673713	The actin cytoskeleton facilitates complement-mediated activation of cytosolic phospholipase A2.
Q34212458	The actin cytoskeleton, membrane lipid microdomains, and T cell signal transduction
Q30442025	The actin-driven movement and formation of acetylcholine receptor clusters
Q28207920	The activity of guanine exchange factor NET1 is essential for transforming growth factor-beta-mediated stress fiber formation
Q28589410	The activity of the GTPase-activating protein CdGAP is regulated by the endocytic protein intersectin
Q28265990	The activity of the plexin-A1 receptor is regulated by Rac
Q30165268	The adaptor protein Nck-1 couples the netrin-1 receptor DCC (deleted in colorectal cancer) to the activation of the small GTPase Rac1 through an atypical mechanism
Q48063554	The aimless RasGEF is required for processing of chemotactic signals through G-protein-coupled receptors in Dictyostelium
Q42131497	The amino acid motif L/IIxxFE defines a novel actin-binding sequence in PDZ-RhoGEF.
Q34045733	The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation.
Q43224863	The antagonistic roles of PDGF and integrin αvβ3 in regulating ROS production at focal adhesions
Q44683576	The apolipoprotein(a) component of lipoprotein(a) stimulates actin stress fiber formation and loss of cell-cell contact in cultured endothelial cells
Q41984711	The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases
Q42796873	The bioactive phospholipid lysophosphatidic acid is released from activated platelets.
Q37899787	The biology of interleukin-1: emerging concepts in the regulation of the actin cytoskeleton and cell junction dynamics
Q34680614	The biology of the combretastatins as tumour vascular targeting agents
Q44352757	The cAMP signaling pathway has opposing effects on Rac and Rho in B16F10 cells: implications for dendrite formation in melanocytic cells
Q73009469	The carboxy-terminal pleckstrin homology domain of ROCK interacts with filamin-A
Q42635431	The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility
Q33957684	The cytoskeleton in lymphocyte signaling
Q27300118	The development of a novel high throughput computational tool for studying individual and collective cellular migration
Q39673989	The diaphanous-related formin mDia1 controls serum response factor activity through its effects on actin polymerization
Q33976892	The differential regulation of cell motile activity through matrix stiffness and porosity in three dimensional collagen matrices
Q37127317	The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion.
Q26751231	The dynamics of spatio-temporal Rho GTPase signaling: formation of signaling patterns
Q39658606	The effect of DNA methylation inhibitor 5-Aza-2'-deoxycytidine on human endometrial stromal cells.
Q36437970	The effect of growth factor environment on fibroblast morphological response to substrate stiffness
Q41497266	The effector domain of Rab6, plus a highly hydrophobic C terminus, is required for Golgi apparatus localization
Q41223130	The effects of hyperthermia on the cytoskeleton: a review
Q48175628	The effects of the selective ROCK inhibitor, Y27632, on ET-1-induced hypertrophic response in neonatal rat cardiac myocytes--possible involvement of Rho/ROCK pathway in cardiac muscle cell hypertrophy
Q35912786	The engulfment process of programmed cell death in caenorhabditis elegans
Q40642587	The extracellular matrix in cellular proliferation and differentiation
Q24308206	The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor
Q30441899	The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis
Q35190950	The formin mDia regulates GSK3beta through novel PKCs to promote microtubule stabilization but not MTOC reorientation in migrating fibroblasts
Q28190582	The formins: active scaffolds that remodel the cytoskeleton
Q28568988	The functional consequence of RhoA knockdown by RNA interference in rat cerebral arteries
Q42797552	The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G(q), G(i) and G(12) proteins
Q35944695	The genetics of hiding the corpse: engulfment and degradation of apoptotic cells in C. elegans and D. melanogaster.
Q37108683	The golgi-associated COPI-coated buds and vesicles contain beta/gamma -actin.
Q42125827	The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.
Q41697096	The guanine nucleotide exchange factor Vav3 regulates differentiation of progenitor cells in the developing mouse retina
Q47071043	The guanine nucleotide exchange factor trio mediates axonal development in the Drosophila embryo
Q24292225	The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function
Q48925369	The human neuronal alpha 1-chimaerin gene contains a position-dependent negative regulatory element in the first exon.
Q34499924	The human orthologue of CdGAP is a phosphoprotein and a GTPase-activating protein for Cdc42 and Rac1 but not RhoA.
Q40212349	The in vitro influences of neurotensin on the motility characteristics of human U373 glioblastoma cells
Q41013953	The inflammatory mediator leukotriene D4 triggers a rapid reorganisation of the actin cytoskeleton in human intestinal epithelial cells
Q42830062	The inhibition of cell spreading on a cellulose substrate (cuprophan) induces an apoptotic process via a mitochondria-dependent pathway.
Q39460559	The insert region of RhoA is essential for Rho kinase activation and cellular transformation
Q28609843	The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly
Q24290570	The interaction of titin and alpha-actinin is controlled by a phospholipid-regulated intramolecular pseudoligand mechanism
Q35120839	The interface between ErbB and non-ErbB receptors in tumor invasion: clinical implications and opportunities for target discovery
Q35920891	The interplay between Src and integrins in normal and tumor biology
Q41948258	The intracellular functions of alpha6beta4 integrin are regulated by EGF.
Q30167844	The intrinsic ability of AFAP-110 to alter actin filament integrity is linked with its ability to also activate cellular tyrosine kinases
Q28567260	The junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brain
Q34670832	The leukocyte cytoskeleton in cell migration and immune interactions
Q28575934	The light chain 1 subunit of the microtubule-associated protein 1B (MAP1B) is responsible for Tiam1 binding and Rac1 activation in neuronal cells
Q42805494	The low M(r) protein-tyrosine phosphatase is involved in Rho-mediated cytoskeleton rearrangement after integrin and platelet-derived growth factor stimulation.
Q24562382	The low molecular mass GTP-binding protein Rho is affected by toxin A from Clostridium difficile
Q24655928	The low-affinity receptor for neurotrophins p75NTR plays a key role for satellite cell function in muscle repair acting via RhoA
Q46861210	The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak
Q34984778	The mechanism of cell membrane ruffling relies on a phospholipase D2 (PLD2), Grb2 and Rac2 association
Q47366682	The minor histocompatibility antigen 1 (HMHA1)/ArhGAP45 is a RacGAP and a novel regulator of endothelial integrity
Q43582683	The mouse lp(A3)/Edg7 lysophosphatidic acid receptor gene: genomic structure, chromosomal localization, and expression pattern
Q24314450	The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains
Q34451888	The neurofibromatosis type 1 gene product neurofibromin enhances cell motility by regulating actin filament dynamics via the Rho-ROCK-LIMK2-cofilin pathway.
Q27348526	The non-catalytic carboxyl-terminal domain of ARFGAP1 regulates actin cytoskeleton reorganization by antagonizing the activation of Rac1
Q24290533	The novel Rho-family GTPase rif regulates coordinated actin-based membrane rearrangements
Q28296458	The nuclear cap-binding complex is a novel target of growth factor receptor-coupled signal transduction
Q91161084	The oligodendrocyte growth cone and its actin cytoskeleton: A fundamental element for progenitor cell migration and CNS myelination
Q24648481	The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton
Q34102000	The p21 GTP-binding proteins and bacterial toxins
Q33746152	The pharmacology of bisphosphonates and new insights into their mechanisms of action
Q40264466	The polycystin 1-C-terminal fragment stimulates ERK-dependent spreading of renal epithelial cells
Q39475047	The potassium-chloride cotransporter 2 promotes cervical cancer cell migration and invasion by an ion transport-independent mechanism
Q42823387	The ras-related small GTP-binding protein RhoB is immediate-early inducible by DNA damaging treatments
Q28578515	The rat myosin myr 5 is a GTPase-activating protein for Rho in vivo: essential role of arginine 1695
Q24299978	The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1
Q91845577	The recurrent postzygotic pathogenic variant p.Glu47Lys in RHOA causes a novel recognizable neuroectodermal phenotype
Q34980429	The regulation of RhoA at focal adhesions by StarD13 is important for astrocytoma cell motility.
Q34189276	The regulation of actin polymerization and cross-linking in Dictyostelium
Q40672022	The requirement for polyamines for intestinal epithelial cell migration is mediated through Rac1.
Q37257352	The rho-specific guanine nucleotide exchange factor Dbs regulates breast cancer cell migration
Q33599408	The role of G proteins in insulin signalling
Q34598154	The role of Rho GTPases and associated kinases in regulating neurite outgrowth
Q40445441	The role of RhoA in the regulation of cell morphology and motility
Q26829930	The role of actin filament dynamics in the myogenic response of cerebral resistance arteries
Q33255052	The role of geranylgeranylated proteins in human mesangial cell proliferation
Q47971728	The role of integrins in tumorigenesis and metastasis
Q54612843	The role of mechanical stretching in the activation and localization of adhesion proteins and related intracellular molecules.
Q38011133	The role of small GTPases in neuronal morphogenesis and polarity
Q30476179	The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells
Q33552436	The secreted Ipa complex of Shigella flexneri promotes entry into mammalian cells
Q50956857	The shift in GH3 cell shape and cell motility is dependent on MLCK and ROCK.
Q28117594	The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase
Q28274364	The small GTP-binding protein RhoA regulates a delayed rectifier potassium channel
Q40569386	The small GTP-binding protein RhoA regulates c-jun by a ROCK-JNK signaling axis.
Q30872192	The small GTP-binding protein TC10 promotes nerve elongation in neuronal cells, and its expression is induced during nerve regeneration in rats.
Q27861063	The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
Q36255734	The small GTP-binding protein rho regulates cortical activities in cultured cells during division
Q29614258	The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
Q40242916	The small GTP-binding proteins, Rac and Rho, regulate cytoskeletal organization and exocytosis in mast cells by parallel pathways
Q47072045	The small GTPase Rac plays multiple roles in epithelial sheet fusion--dynamic studies of Drosophila dorsal closure
Q52549888	The small GTPase Rho4 is involved in controlling cell morphology and septation in fission yeast.
Q39863613	The small GTPase Rif is an alternative trigger for the formation of actin stress fibers in epithelial cells
Q42796070	The small GTPases Cdc42Hs, Rac1 and RhoG delineate Raf-independent pathways that cooperate to transform NIH3T3 cells
Q57910039	The small GTPases Rac and Rho as regulators of secretion in mast cells
Q37977187	The small Rho GTPase Rif and actin cytoskeletal remodelling
Q39618243	The small peptide OGP(10-14) reduces proliferation and induces differentiation of TPO-primed M07-e cells through RhoA/TGFbeta1/SFK pathway.
Q22011010	The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1
Q38876338	The structure of FMNL2-Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation.
Q27734671	The structure of the GTPase-activating domain from p50rhoGAP
Q36525640	The tension mounts: stress fibers as force-generating mechanotransducers
Q42687168	The three-dimensional model of Dictyostelium discoideum racE based on the human rhoA-GDP crystal structure
Q30989694	The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways
Q30541086	The tone of pulmonary smooth muscle: ROK and Rho music?
Q36255893	The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells.
Q28207839	The tyrosine kinase ACK1 associates with clathrin-coated vesicles through a binding motif shared by arrestin and other adaptors
Q36756648	The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts.
Q57976989	The yeast exchange assay, a new complementary method to screen for Dbl-like protein specificity: identification of a novel RhoA exchange factor
Q37824818	Therapeutic effects of Clostridium botulinum C3 exoenzyme
Q46479843	Threshold levels of ERK activation for chemotactic migration differ for NGF and EGF in rat pheochromocytoma PC12 cells
Q28261735	Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells
Q46007653	Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities.
Q24291476	Thy-1 binds to integrin beta(3) on astrocytes and triggers formation of focal contact sites
Q24337206	Thy-1 regulates fibroblast focal adhesions, cytoskeletal organization and migration through modulation of p190 RhoGAP and Rho GTPase activity
Q34684502	Thy-1-induced migration inhibition in vascular endothelial cells through reducing the RhoA activity
Q40163925	Thyroid hormones reorganize the cytoskeleton of glial cells through Gfap phosphorylation and Rhoa-dependent mechanisms
Q42823589	Timing of cyclin D1 expression within G1 phase is controlled by Rho.
Q42217527	Tipifarnib in the treatment of acute myeloid leukemia
Q33892761	Tissue stretch induces nuclear remodeling in connective tissue fibroblasts
Q44195410	Tissue transglutaminase mediates activation of RhoA and MAP kinase pathways during retinoic acid-induced neuronal differentiation of SH-SY5Y cells
Q33540128	Tobacco mosaic virus. Pioneering research for a century
Q54978240	Toll-like receptor signaling in macrophages is regulated by extracellular substrate stiffness and Rho-associated coiled-coil kinase (ROCK1/2).
Q34427589	Topological and functional properties of the small GTPases protein interaction network
Q54564124	Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine.
Q36519045	Transcription factors control invasion: AP-1 the first among equals
Q28180053	Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells
Q41078745	Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin-dependent pathway
Q34226022	Transforming G proteins
Q39412554	Transforming growth factor-beta1 (TGFbeta1) stimulates connective tissue growth factor (CCN2/CTGF) expression in human gingival fibroblasts through a RhoA-independent, Rac1/Cdc42-dependent mechanism: statins with forskolin block TGFbeta1-induced CCN
Q24600173	Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism
Q40286383	Transforming growth factor-beta1-induced endothelial barrier dysfunction involves Smad2-dependent p38 activation and subsequent RhoA activation
Q39823228	Transient expression of RhoA, -B, and -C GTPases in HeLa cells potentiates resistance to Clostridium difficile toxins A and B but not to Clostridium sordellii lethal toxin
Q50239549	Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes.
Q40698661	Translocation of Na(+),K(+)-ATPase is induced by Rho small GTPase in renal epithelial cells.
Q42803603	Translocation of Src kinase to the cell periphery is mediated by the actin cytoskeleton under the control of the Rho family of small G proteins
Q34279269	Treatment with the vascular disrupting agent combretastatin is associated with impaired AQP2 trafficking and increased urine output
Q39231741	Tumor necrosis factor-alpha induces stress fiber formation through ceramide production: role of sphingosine kinase.
Q40648585	Tumor necrosis factor-alpha promotes survival of opossum kidney cells via Cdc42-induced phospholipase C-gamma1 activation and actin filament redistribution
Q40169273	Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility
Q37008845	Tumour targeting by microtubule-depolymerizing vascular disrupting agents
Q37464162	Tumour-suppressor microRNAs regulate ovarian cancer cell physical properties and invasive behaviour.
Q33483712	Twist expression promotes migration and invasion in hepatocellular carcinoma
Q28289697	Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome
Q41323243	Two SH2 Domains of p120 Ras GTPase-activating Protein Bind Synergistically to Tyrosine Phosphorylated p190 Rho GTPase-activating Protein
Q24338465	Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin
Q33552605	Type III secretion-dependent cell cycle block caused in HeLa cells by enteropathogenic Escherichia coli O103.
Q57899443	Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly
Q30452619	Tyrosine 807 of the v-Fms oncogene product controls cell morphology and association with p120RasGAP.
Q28272316	Tyrosine kinases EnAbling adaptor molecules for chemokine-induced Rap1 activation in T cells
Q36382744	Tyrosine phosphorylation and cytoskeletal tension regulate the release of fibroblast adhesions
Q41942809	Tyrosine phosphorylation of focal adhesion kinase and paxillin regulates the signaling mechanism of the rapid nongenomic action of dexamethasone on actin cytoskeleton
Q41727098	Tyrosine phosphorylation of p125(Fak), p130(Cas), and paxillin does not require extracellular signal-regulated kinase activation in Swiss 3T3 cells stimulated by bombesin or platelet-derived growth factor
Q28507631	Tyrosine phosphorylation of p130(cas) by bombesin, lysophosphatidic acid, phorbol esters, and platelet-derived growth factor. Signaling pathways and formation of a p130(cas)-Crk complex
Q28118175	Tyrosine phosphorylation of paxillin and focal adhesion kinase by activation of muscarinic m3 receptors is dependent on integrin engagement by the extracellular matrix
Q46103419	UNC-115, a conserved protein with predicted LIM and actin-binding domains, mediates axon guidance in C. elegans
Q42834338	Uncoordinated regulation of stress fibers and focal adhesions by DAP kinase
Q41240869	Unfarnesylated transforming Ras mutant inhibits the Ras-signaling pathway by forming a stable Ras.Raf complex in the cytosol
Q27674197	Unique structural and nucleotide exchange features of the Rho1 GTPase of Entamoeba histolytica.
Q52848457	Upregulation of Hic-5 in glomerulosclerosis and its regulation of mesangial cell apoptosis.
Q31035986	Uptake and trafficking of DNA in keratinocytes: evidence for DNA-binding proteins
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Q36225790	Zyxin is a transforming growth factor-β (TGF-β)/Smad3 target gene that regulates lung cancer cell motility via integrin α5β1.
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P356	DOI	10.1016/0092-8674(92)90163-7
P953	full work available at URL	https://api.elsevier.com/content/article/PII:0092867492901637?httpAccept=text/plain
		https://api.elsevier.com/content/article/PII:0092867492901637?httpAccept=text/xml
P3181	OpenCitations bibliographic resource ID	351822
P698	PubMed publication ID	1643657

P50	author	Anne Ridley	Q21254312
P2093	author name string	A. Hall
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P433	issue	3
P407	language of work or name	English	Q1860
P921	main subject	focal adhesion	Q904514
		cell-substrate junction	Q14864266
		Ras homolog family member A	Q15331521
P304	page(s)	389-99
P577	publication date	1992-08-07
P1433	published in	Cell	Q655814
P1476	title	The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
P478	volume	70

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

scientific article (publication date: 7 August 1992)

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