The rho gene product expressed in E. coli is a substrate of botulinum ADP-ribosyltransferase C3.

scientific article

The rho gene product expressed in E. coli is a substrate of botulinum ADP-ribosyltransferase C3. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0006-291X(89)80199-8
P698PubMed publication ID2492192

P2093author name stringHall A
Aktories K
Braun U
Just I
Rösener S
P2860cites workA novel ras-related gene familyQ24300094
Coding sequence of human rho cDNAs clone 6 and clone 9Q24615845
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
G proteins: transducers of receptor-generated signalsQ29547519
ras genesQ29547799
Functional modification of a 21-kilodalton G protein when ADP-ribosylated by exoenzyme C3 of Clostridium botulinumQ36781144
Botulinum toxin-induced ADP-ribosylation and inhibition of exocytosis are unrelated eventsQ41390659
ADP-ribosylation of a 21-24 kDa eukaryotic protein(s) by C3, a novel botulinum ADP-ribosyltransferase, is regulated by guanine nucleotideQ42164610
Clostridium botulinum type C produces a novel ADP-ribosyltransferase distinct from botulinum C2 toxin.Q54411689
Botulinum ADP-ribosyltransferase C3 but not botulinum neurotoxins C1 and D ADP-ribosylates low molecular mass GTP-binding proteinsQ70366509
Botulinum ADP-ribosyltransferase C3. Purification of the enzyme and characterization of the ADP-ribosylation reaction in platelet membranesQ70381308
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
P304page(s)209-213
P577publication date1989-01-01
P1433published inBiochemical and Biophysical Research CommunicationsQ864228
P1476titleThe rho gene product expressed in E. coli is a substrate of botulinum ADP-ribosyltransferase C3.
P478volume158

Reverse relations

cites work (P2860)
Q30301325A complex of p190RhoGAP-A and anillin modulates RhoA-GTP and the cytokinetic furrow in human cells
Q31743399A novel C3-like ADP-ribosyltransferase from Staphylococcus aureus modifying RhoE and Rnd3.
Q24564664A novel role for RhoGDI as an inhibitor of GAP proteins
Q42475021A role for Rho and Rac in secretagogue-induced amylase release by pancreatic acini.
Q47239880A role for the small molecular weight GTPases, Rho and Cdc42, in muscarinic receptor signaling to focal adhesion kinase
Q24654174A single receptor encoded by vzg-1/lpA1/edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid
Q42825916A small GTP-binding protein, Rho, associates with the platelet-derived growth factor type-beta receptor upon ligand binding.
Q30556991A spindle-independent cleavage pathway controls germ cell formation in Drosophila
Q51696863ADP-Ribosylation and Cross-Linking of Actin by Bacterial Protein Toxins.
Q68078989ADP-ribosylation by Clostridium botulinum C3 exoenzyme increases steady-state GTPase activities of recombinant rhoA and rhoB proteins
Q41963968ADP-ribosylation of Rho proteins by Clostridium botulinum exoenzyme C3 is influenced by phosphorylation of Rho-associated factors
Q41660150ADP-ribosylation of a small size GTP-binding protein in bovine neutrophils by the C3 exoenzyme of Clostridium botulinum and effect on the cell motility
Q68099217ADP-ribosylation of small GTP-binding proteins by Bacillus cereus
Q37861900Actin as target for modification by bacterial protein toxins
Q41784777Actin filament organization in activated mast cells is regulated by heterotrimeric and small GTP-binding proteins
Q39573446Activation of Rho GTPases by Escherichia coli cytotoxic necrotizing factor 1 increases intestinal permeability in Caco-2 cells
Q30486421Antigen-independent adhesion and cell spreading by inducible costimulator engagement inhibits T cell migration in a PI-3K-dependent manner
Q73801981Astrocyte spreading in response to thrombin and lysophosphatidic acid is dependent on the Rho GTPase
Q33675805Bacillus cereus Certhrax ADP-ribosylates vinculin to disrupt focal adhesion complexes and cell adhesion
Q36094307Bacterial cytotoxins: targeting eukaryotic switches
Q37890245Bacterial protein toxins that modify host regulatory GTPases
Q24562788Binary bacterial toxins: biochemistry, biology, and applications of common Clostridium and Bacillus proteins
Q37371588Bombesin-induced gastrin release from canine G cells is stimulated by Ca2+ but not by protein kinase C, and is enhanced by disruption of rho/cytoskeletal pathways
Q40492009C3 transferase gene therapy for continuous conditional RhoA inhibition
Q28255939Cdk1-dependent mitotic enrichment of cortical myosin II promotes cell rounding against confinement
Q51334188Cell Entry of C3 Exoenzyme from Clostridium botulinum.
Q40345213Cell proliferation and drug resistance in hepatocellular carcinoma are modulated by Rho GTPase signals
Q36988160Characterization of the C3 gene of Clostridium botulinum types C and D and its expression in Escherichia coli
Q42987313Characterization of the intracellular signalling pathways that underlie growth-factor-stimulated glucose transport in Xenopus oocytes: evidence for ras- and rho-dependent pathways of phosphatidylinositol 3-kinase activation
Q27006253Chemical reporters for exploring ADP-ribosylation and AMPylation at the host-pathogen interface
Q35669797Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin
Q40616444Clostridial ADP-ribosylating toxins: effects on ATP and GTP-binding proteins
Q37824925Clostridial ADP-ribosyltransferases--modification of low molecular weight GTP-binding proteins and of actin by clostridial toxins
Q33860004Clostridium difficile toxin B differentially affects GPCR-stimulated Ca2+ responses in macrophages: independent roles for Rho and PLA2.
Q38931721Comparative Studies of Actin- and Rho-Specific ADP-Ribosylating Toxins: Insight from Structural Biology.
Q24806593Control of T lymphocyte morphology by the GTPase Rho.
Q44243354Cooperative regulation by Rac and Rho of agrin-induced acetylcholine receptor clustering in muscle cells
Q39490343Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme
Q27650023Crystal structure of the Clostridium limosum C3 exoenzyme
Q42828475Direct involvement of the small GTP-binding protein Rho in lbc oncogene function
Q39653853Dominant-negative Rho, Rac, and Cdc42 facilitate the invasion process of Vibrio parahaemolyticus into Caco-2 cells
Q90196452Engineering Photorhabdus luminescens toxin complex (PTC) into a recombinant injection nanomachine
Q38341362EphA4, RhoB and the molecular development of feather buds are maintained by the integrity of the actin cytoskeleton.
Q42056986Evidence that atypical protein kinase C-lambda and atypical protein kinase C-zeta participate in Ras-mediated reorganization of the F-actin cytoskeleton.
Q41032320From RAS to RHO: The making of the great cell biologist Alan Hall (1952-2015).
Q38104533Hijacking of Rho GTPases during bacterial infection
Q36865742Host cell cytotoxicity and cytoskeleton disruption by CerADPr, an ADP-ribosyltransferase of Bacillus cereus G9241
Q24324005IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs
Q47921604Identification of a potential effector pathway for the trimeric Go protein associated with secretory granules. Go stimulates a granule-bound phosphatidylinositol 4-kinase by activating RhoA in chromaffin cells
Q30803862Identification of the C-terminal part of Bordetella dermonecrotic toxin as a transglutaminase for rho GTPases
Q30782754Identification of the region of rho involved in substrate recognition by Escherichia coli cytotoxic necrotizing factor 1 (CNF1).
Q42492146Importance of spatial activation of Cdc42 and rac small G proteins by frabin for microspike formation in MDCK cells
Q74801438Inhibition of Pollen Tube Elongation by Microinjected Anti-Rop1Ps Antibodies Suggests a Crucial Role for Rho-Type GTPases in the Control of Tip Growth
Q42810716Inhibition of RhoGAP activity is sufficient for the induction of Rho-mediated actin reorganization
Q40578173Integrin alpha4beta1 involvement in stromal cell-derived factor-1alpha-promoted myeloma cell transendothelial migration and adhesion: role of cAMP and the actin cytoskeleton in adhesion.
Q46761038Interaction of mastoparan with the low molecular mass GTP-binding proteins rho/rac
Q67288720Interaction of small G proteins with photoexcited rhodopsin
Q43888109Interaction of the Rho-ADP-ribosylating C3 exoenzyme with RalA.
Q36596684Is caveolin-1 a viable therapeutic target to reduce cancer metastasis?
Q73208292Lysophosphatidic acid sensitizes mechanical stress-induced Ca2+ response via activation of phospholipase C and tyrosine kinase in cultured smooth muscle cells
Q24678787Microinjection of recombinant p21rho induces rapid changes in cell morphology
Q36549762Molecular cloning and characterization of rho, a ras-related small GTP-binding protein from the garden pea.
Q33936764Molecular recognition of an ADP-ribosylating Clostridium botulinum C3 exoenzyme by RalA GTPase
Q38229329Novel bacterial ADP-ribosylating toxins: structure and function
Q30482822Nuf, a Rab11 effector, maintains cytokinetic furrow integrity by promoting local actin polymerization
Q37555597Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system
Q52552671Phenotypic modulation of cultured bladder smooth muscle cells and the expression of inducible nitric oxide synthase.
Q41882877Prenylated protein methyltransferases do not distinguish between farnesylated and geranylgeranylated substrates
Q54668963Production of an antiserum specific to the ADP-ribosylated form of elongation factor 2 from archaebacteria and eukaryotes.
Q41251491Rac1 GTPase-deficient HeLa cells present reduced DNA repair, proliferation, and survival under UV or gamma irradiation
Q44868059Rac1, a low-molecular-mass GTP-binding-protein with high intrinsic GTPase activity and distinct biochemical properties
Q39697059Rapid up-regulation of alpha4 integrin-mediated leukocyte adhesion by transforming growth factor-beta1.
Q43878348Rearrangement of the cytoskeletal network induced by platelet-derived growth factor in rat hepatic stellate cells: role of different intracellular signalling pathways
Q37781061Recent insights into Pasteurella multocida toxin and other G-protein-modulating bacterial toxins
Q48000569Regulation of TNF-alpha-induced reorganization of the actin cytoskeleton and cell-cell junctions by Rho, Rac, and Cdc42 in human endothelial cells
Q24815968Regulation of pancreatic cancer cell migration and invasion by RhoC GTPase and caveolin-1
Q40021756Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells
Q74339098Regulation of somatodendritic GABAA receptor channels in rat hippocampal neurons: evidence for a role of the small GTPase Rac1
Q39984874Rho GTPases in PC-3 prostate cancer cell morphology, invasion and tumor cell diapedesis
Q40588907Rho is involved in superoxide formation during phagocytosis of opsonized zymosans
Q41091270Rho is required for the initiation of calcium signaling and phagocytosis by Fcgamma receptors in macrophages
Q41077461Rho prevents apoptosis through Bcl-2 expression: implications for interleukin-2 receptor signal transduction
Q24563849Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia
Q37369834Rho proteins play a critical role in cell migration during the early phase of mucosal restitution
Q34406193Rho-ROCK and Rac-PAK signaling pathways have opposing effects on the cell-to-cell spread of Marek's Disease Virus
Q35681634Rho-regulatory proteins in breast cancer cell motility and invasion
Q42437398RhoA and microtubule dynamics control cell-basement membrane interaction in EMT during gastrulation
Q38610718RhoA-dependent phosphorylation and relocalization of ERM proteins into apical membrane/actin protrusions in fibroblasts
Q28284154RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility
Q24303641Rocks: multifunctional kinases in cell behaviour
Q42004714Rundown of somatodendritic N-methyl-D-aspartate (NMDA) receptor channels in rat hippocampal neurones: evidence for a role of the small GTPase RhoA
Q40792108Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase
Q37138723Small G proteins as key regulators of pancreatic digestive enzyme secretion.
Q42830146Snails, Swiss, and serum: the solution for Rac 'n' Rho.
Q35782703SpyA is a membrane-bound ADP-ribosyltransferase of Streptococcus pyogenes which modifies a streptococcal peptide, SpyB.
Q36256190Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases
Q92604440Targeting ADP-ribosylation as an antimicrobial strategy
Q37808971Targeting of the actin cytoskeleton by insecticidal toxins from Photorhabdus luminescens
Q42831845The G-protein G13 but not G12 mediates signaling from lysophosphatidic acid receptor via epidermal growth factor receptor to Rho.
Q33863444The Rho GTP exchange factor Lfc promotes spindle assembly in early mitosis
Q34398250The Rho-ADP-ribosylating C3 exoenzyme from Clostridium botulinum and related C3-like transferases
Q34190151The Rho/ROCK pathway mediates neurite growth-inhibitory activity associated with the chondroitin sulfate proteoglycans of the CNS glial scar
Q44352757The cAMP signaling pathway has opposing effects on Rac and Rho in B16F10 cells: implications for dendrite formation in melanocytic cells
Q27641890The crystal structure of C3stau2 from Staphylococcus aureus and its complex with NAD
Q34085628The effects of the small GTPase RhoA on the muscarinic contraction of airway smooth muscle result from its role in regulating actin polymerization.
Q35190950The formin mDia regulates GSK3beta through novel PKCs to promote microtubule stabilization but not MTOC reorientation in migrating fibroblasts
Q37108683The golgi-associated COPI-coated buds and vesicles contain beta/gamma -actin.
Q40639908The host cell chaperone Hsp90 is essential for translocation of the binary Clostridium botulinum C2 toxin into the cytosol
Q40445441The role of RhoA in the regulation of cell morphology and motility
Q27860467The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
Q40242916The small GTP-binding proteins, Rac and Rho, regulate cytoskeletal organization and exocytosis in mast cells by parallel pathways
Q57910039The small GTPases Rac and Rho as regulators of secretion in mast cells
Q30413746Thrombin receptor and RhoA mediate cell proliferation through integrins and cysteine-rich protein 61.
Q39412554Transforming growth factor-beta1 (TGFbeta1) stimulates connective tissue growth factor (CCN2/CTGF) expression in human gingival fibroblasts through a RhoA-independent, Rac1/Cdc42-dependent mechanism: statins with forskolin block TGFbeta1-induced CCN
Q40698661Translocation of Na(+),K(+)-ATPase is induced by Rho small GTPase in renal epithelial cells.
Q42638371Why should cell biologists study microbial pathogens?
Q44205887p75NTR-dependent, myelin-mediated axonal degeneration regulates neural connectivity in the adult brain

Search more.