review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Matthias Geyer | Q63363890 |
P2093 | author name string | Sonja Kühn | |
P2860 | cites work | Characterization of Diaphanous-related formin FMNL2 in human tissues | Q21284188 |
Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets | Q24307657 | ||
The mammalian formin FHOD1 is activated through phosphorylation by ROCK and mediates thrombin-induced stress fibre formation in endothelial cells | Q24309382 | ||
Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis | Q24310527 | ||
Bi-modal regulation of a formin by srGAP2 | Q24315079 | ||
Structure of the autoinhibitory switch in formin mDia1. | Q34493635 | ||
RhoB and the mammalian Diaphanous-related formin mDia2 in endosome trafficking | Q34596684 | ||
The formin DAD domain plays dual roles in autoinhibition and actin nucleation. | Q34683336 | ||
FHOD1, a formin upregulated in epithelial-mesenchymal transition, participates in cancer cell migration and invasion | Q35005232 | ||
The formin mDia regulates GSK3beta through novel PKCs to promote microtubule stabilization but not MTOC reorientation in migrating fibroblasts | Q35190950 | ||
RhoA and RhoC have distinct roles in migration and invasion by acting through different targets | Q35196063 | ||
Dynamic remodeling of the actin cytoskeleton by FMNL1γ is required for structural maintenance of the Golgi complex | Q35210823 | ||
Daam2 is required for dorsal patterning via modulation of canonical Wnt signaling in the developing spinal cord | Q35690673 | ||
mDia1 and WAVE2 proteins interact directly with IRSp53 in filopodia and are involved in filopodium formation | Q35763102 | ||
Daam1 regulates the endocytosis of EphB during the convergent extension of the zebrafish notochord | Q35800339 | ||
The PCH family protein, Cdc15p, recruits two F-actin nucleation pathways to coordinate cytokinetic actin ring formation in Schizosaccharomyces pombe | Q36323291 | ||
Cellular functions of the Spir actin-nucleation factors | Q36562415 | ||
Comparative gene expression analysis of the fmnl family of formins during zebrafish development and implications for tissue specific functions | Q36581924 | ||
Two distinct phosphorylation events govern the function of muscle FHOD3. | Q36968593 | ||
Apical targeting of the formin Diaphanous in Drosophila tubular epithelia | Q36998821 | ||
IRSp53: crossing the road of membrane and actin dynamics in the formation of membrane protrusions | Q37063714 | ||
Daam1a mediates asymmetric habenular morphogenesis by regulating dendritic and axonal outgrowth | Q37177993 | ||
Spire and Cordon-bleu: multifunctional regulators of actin dynamics | Q37262049 | ||
Formin-like 1 (FMNL1) is regulated by N-terminal myristoylation and induces polarized membrane blebbing. | Q37446184 | ||
Formin follows function: a muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenance | Q24315677 | ||
p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin | Q24316148 | ||
Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation | Q24318404 | ||
The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics | Q24319184 | ||
Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration | Q24321510 | ||
The Diaphanous-related Formin FHOD1 associates with ROCK1 and promotes Src-dependent plasma membrane blebbing | Q24322829 | ||
Planar cell polarity links axes of spatial dynamics in neural-tube closure | Q24336656 | ||
FRL, a novel formin-related protein, binds to Rac and regulates cell motility and survival of macrophages | Q24551450 | ||
Rho3 of Saccharomyces cerevisiae, which regulates the actin cytoskeleton and exocytosis, is a GTPase which interacts with Myo2 and Exo70 | Q24554501 | ||
A conserved mechanism for Bni1- and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin | Q24624729 | ||
Mechanism of activation of the Formin protein Daam1 | Q24657453 | ||
The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src | Q24670372 | ||
Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism | Q24679102 | ||
FH3, a domain found in formins, targets the fission yeast formin Fus1 to the projection tip during conjugation | Q24680239 | ||
Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly | Q24681958 | ||
Autoinhibition regulates cellular localization and actin assembly activity of the diaphanous-related formins FRLalpha and mDia1. | Q24682983 | ||
Stress fibers are generated by two distinct actin assembly mechanisms in motile cells | Q24683694 | ||
Formins at a glance | Q27009102 | ||
DAAM1 is a formin required for centrosome re-orientation during cell migration | Q27318753 | ||
Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells | Q27333967 | ||
Diaphanous-related formin 2 and profilin I are required for gastrulation cell movements | Q27438166 | ||
The human formin FHOD1 contains a bipartite structure of FH3 and GTPase-binding domains required for activation | Q27652093 | ||
Specificity of Interactions between mDia Isoforms and Rho Proteins | Q27652343 | ||
The Structure of the N-Terminus of Kindlin-1: A Domain Important for αIIbβ3 Integrin Activation | Q27657671 | ||
Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation | Q27659768 | ||
Crystal Structure of a Complex between Amino and Carboxy Terminal Fragments of mDia1: Insights into Autoinhibition of Diaphanous-Related Formins | Q27664937 | ||
Crystal Structure of the Formin mDia1 in Autoinhibited Conformation | Q27664938 | ||
Structure, Dynamics, Lipid Binding, and Physiological Relevance of the Putative GTPase-binding Domain of Dictyostelium Formin C | Q27671794 | ||
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors | Q27860467 | ||
Formin Leaky Cap Allows Elongation in the Presence of Tight Capping Proteins | Q27935256 | ||
Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae | Q27936679 | ||
RhoGEF2 and the formin Dia control the formation of the furrow canal by directed actin assembly during Drosophila cellularisation. | Q45249865 | ||
Control of the assembly of ATP- and ADP-actin by formins and profilin. | Q45345926 | ||
The filamentous actin cross-linking/bundling activity of mammalian formins. | Q46331574 | ||
Structural and mechanistic insights into the interaction between Rho and mammalian Dia. | Q46466555 | ||
The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia. | Q46503087 | ||
Formin-induced actin cables are required for polarized recruitment of the Ste5 scaffold and high level activation of MAPK Fus3. | Q46551366 | ||
Fhos2, a novel formin-related actin-organizing protein, probably associates with the nestin intermediate filament | Q46556615 | ||
The Drosophila formin DAAM regulates the tracheal cuticle pattern through organizing the actin cytoskeleton. | Q46937541 | ||
High expression of FMNL1 protein in T non-Hodgkin's lymphomas | Q46957907 | ||
ForC lacks canonical formin activity but bundles actin filaments and is required for multicellular development of Dictyostelium cells | Q47882536 | ||
FMNL1 promotes proliferation and migration of leukemia cells. | Q50337087 | ||
Structural basis of Rho GTPase-mediated activation of the formin mDia1. | Q50337106 | ||
Mutations in the Rho1 small GTPase disrupt morphogenesis and segmentation during early Drosophila development. | Q52173284 | ||
T cell responses in mammalian diaphanous-related formin mDia1 knock-out mice. | Q52580057 | ||
Loss of a Rho-regulated actin nucleator, mDia2, impairs cytokinesis during mouse fetal erythropoiesis. | Q53082928 | ||
WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2. | Q53782742 | ||
FHOD1 is a combined actin filament capping and bundling factor that selectively associates with actin arcs and stress fibers | Q56964060 | ||
The small GTPase Rho3 and the diaphanous/formin For3 function in polarized cell growth in fission yeast | Q78470457 | ||
Dynamic localization and function of Bni1p at the sites of directed growth in Saccharomyces cerevisiae | Q27937372 | ||
Formin-dependent actin assembly is regulated by distinct modes of Rho signaling in yeast | Q27939574 | ||
Bni1p implicated in cytoskeletal control is a putative target of Rho1p small GTP binding protein in Saccharomyces cerevisiae | Q27940300 | ||
Aurora B regulates formin mDia3 in achieving metaphase chromosome alignment | Q28119054 | ||
Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2 | Q28144520 | ||
Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42 | Q28188673 | ||
The formin/diaphanous-related protein, FHOS, interacts with Rac1 and activates transcription from the serum response element | Q28190692 | ||
Localization of a mammalian homolog of diaphanous, mDia1, to the mitotic spindle in HeLa cells | Q28199851 | ||
mDia mediates Rho-regulated formation and orientation of stable microtubules | Q28210597 | ||
Fhos, a mammalian formin, directly binds to F-actin via a region N-terminal to the FH1 domain and forms a homotypic complex via the FH2 domain to promote actin fiber formation | Q28212226 | ||
Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1 | Q28214701 | ||
Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture | Q28248937 | ||
Cdc42 and mDia3 regulate microtubule attachment to kinetochores | Q28256623 | ||
Profilin is an effector for Daam1 in non-canonical Wnt signaling and is required for vertebrate gastrulation | Q28267022 | ||
Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7 | Q28267048 | ||
Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC | Q28271418 | ||
Biochemical characterization of the diaphanous autoregulatory interaction in the formin homology protein FHOD1 | Q28287470 | ||
Mechanism and function of formins in the control of actin assembly | Q28293947 | ||
FHOD1 interaction with nesprin-2G mediates TAN line formation and nuclear movement | Q28505650 | ||
Expression and subcellular localization of mammalian formin Fhod3 in the embryonic and adult heart | Q28513956 | ||
Mammalian formin fhod3 regulates actin assembly and sarcomere organization in striated muscles | Q28571176 | ||
Integration of left-right Pitx2 transcription and Wnt signaling drives asymmetric gut morphogenesis via Daam2 | Q28586161 | ||
The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition | Q28586353 | ||
Cooperation between mDia1 and ROCK in Rho-induced actin reorganization | Q28587275 | ||
Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling | Q28646114 | ||
Mammalian formin Fhod3 plays an essential role in cardiogenesis by organizing myofibrillogenesis | Q29347301 | ||
Regulation of actin filament assembly by Arp2/3 complex and formins | Q29615161 | ||
A nucleator arms race: cellular control of actin assembly | Q29616146 | ||
The BAR domain superfamily: membrane-molding macromolecules | Q30014845 | ||
Dia-interacting protein modulates formin-mediated actin assembly at the cell cortex. | Q30158011 | ||
Regulation of the formin for3p by cdc42p and bud6p | Q30480139 | ||
Coordination of microtubule and microfilament dynamics by Drosophila Rho1, Spire and Cappuccino | Q30480159 | ||
mDia2 induces the actin scaffold for the contractile ring and stabilizes its position during cytokinesis in NIH 3T3 cells | Q30481840 | ||
Regulation and targeting of the fission yeast formin cdc12p in cytokinesis | Q30481843 | ||
The microtubule-binding protein CLIP-170 coordinates mDia1 and actin reorganization during CR3-mediated phagocytosis | Q30485142 | ||
Characterization of the biochemical properties and biological function of the formin homology domains of Drosophila DAAM. | Q30494160 | ||
Assembly of filopodia by the formin FRL2 (FMNL3) | Q30497461 | ||
The formin FRL1 (FMNL1) is an essential component of macrophage podosomes | Q30505923 | ||
RhoD activated by fibroblast growth factor induces cytoneme-like cellular protrusions through mDia3C. | Q30528815 | ||
Rocket launcher mechanism of collaborative actin assembly defined by single-molecule imaging | Q30538297 | ||
The formins FMNL1 and mDia1 regulate coiling phagocytosis of Borrelia burgdorferi by primary human macrophages | Q30539638 | ||
The formin FMNL3 is a cytoskeletal regulator of angiogenesis | Q30539874 | ||
Directing exocrine secretory vesicles to the apical membrane by actin cables generated by the formin mDia1. | Q30541010 | ||
Spatiotemporal organization of Aurora-B by APC/CCdh1 after mitosis coordinates cell spreading through FHOD1. | Q30541101 | ||
The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility | Q30547698 | ||
Analysis of the local organization and dynamics of cellular actin networks | Q30547708 | ||
Identification of a carboxyl-terminal diaphanous-related formin homology protein autoregulatory domain | Q31465756 | ||
Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia. | Q34043243 | ||
RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase | Q34176256 | ||
The C terminus of formin FMNL3 accelerates actin polymerization and contains a WH2 domain-like sequence that binds both monomers and filament barbed ends | Q34233588 | ||
Human leukocyte formin: a novel protein expressed in lymphoid malignancies and associated with Akt. | Q34273594 | ||
The mouse formin, FRLalpha, slows actin filament barbed end elongation, competes with capping protein, accelerates polymerization from monomers, and severs filaments | Q34301887 | ||
An 8.9 Mb 19p13 duplication associated with precocious puberty and a sporadic 3.9 Mb 2q23.3q24.1 deletion containing NR4A2 in mentally retarded members of a family with an intrachromosomal 19p-into-19q between-arm insertion | Q34326690 | ||
EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration | Q34341177 | ||
Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis | Q34422795 | ||
Mechanisms of plasma membrane targeting of formin mDia2 through its amino terminal domains | Q34489876 | ||
FHOD1 is needed for directed forces and adhesion maturation during cell spreading and migration | Q37473452 | ||
The role of formins in human disease. | Q37639554 | ||
Fifteen formins for an actin filament: a molecular view on the regulation of human formins. | Q37681690 | ||
WASH, WHAMM and JMY: regulation of Arp2/3 complex and beyond | Q37796281 | ||
Structural and functional insights into the Spir/formin actin nucleator complex | Q38122288 | ||
Physiological roles of Rho and Rho effectors in mammals | Q38158776 | ||
Proteomic investigation of the interactome of FMNL1 in hematopoietic cells unveils a role in calcium-dependent membrane plasticity. | Q38460722 | ||
FMNL2 is a positive regulator of cell motility and metastasis in colorectal carcinoma | Q38502636 | ||
FHOD1 regulates stress fiber organization by controlling the dynamics of transverse arcs and dorsal fibers. | Q39028670 | ||
Formin-mediated actin polymerization promotes Salmonella invasion | Q39123404 | ||
Flightless-I (Fli-I) regulates the actin assembly activity of diaphanous-related formins (DRFs) Daam1 and mDia1 in cooperation with active Rho GTPase. | Q39289697 | ||
Dissecting requirements for auto-inhibition of actin nucleation by the formin, mDia1. | Q39372922 | ||
The multiplicity of human formins: Expression patterns in cells and tissues | Q39427797 | ||
Enhancement of mDia2 activity by Rho-kinase-dependent phosphorylation of the diaphanous autoregulatory domain | Q39519441 | ||
Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse | Q39546199 | ||
FMNL2 enhances invasion of colorectal carcinoma by inducing epithelial-mesenchymal transition | Q39632868 | ||
The yeast formin Bnr1p has two localization regions that show spatially and temporally distinct association with septin structures | Q39851210 | ||
Filopodia formation induced by active mDia2/Drf3. | Q39858881 | ||
Formin proteins of the DAAM subfamily play a role during axon growth. | Q39909551 | ||
Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2. | Q40014693 | ||
The diaphanous inhibitory domain/diaphanous autoregulatory domain interaction is able to mediate heterodimerization between mDia1 and mDia2. | Q40089959 | ||
Identification of genes downregulated in tumor cells expressing antisense glutaminase mRNA by differential display | Q40350138 | ||
RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1. | Q40412034 | ||
Structure and activity of full-length formin mDia1 | Q41762564 | ||
Control of axon elongation via an SDF-1alpha/Rho/mDia pathway in cultured cerebellar granule neurons. | Q41830984 | ||
Rho and anillin-dependent control of mDia2 localization and function in cytokinesis | Q41854360 | ||
FMNL2 drives actin-based protrusion and migration downstream of Cdc42. | Q42188467 | ||
FORMIN stable kinetochore-microtubule attachments | Q42534187 | ||
The basic region of the diaphanous-autoregulatory domain (DAD) is required for autoregulatory interactions with the diaphanous-related formin inhibitory domain | Q42675963 | ||
Diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene. | Q42687958 | ||
Essential role for beta-arrestin 2 in the regulation of Xenopus convergent extension movements | Q42791086 | ||
Activation of the Rac-binding partner FHOD1 induces actin stress fibers via a ROCK-dependent mechanism | Q42799513 | ||
Interaction of the N- and C-terminal autoregulatory domains of FRL2 does not inhibit FRL2 activity. | Q42807829 | ||
The Rho family GTPase Rif induces filopodia through mDia2. | Q42818923 | ||
Nuclear actin network assembly by formins regulates the SRF coactivator MAL. | Q42823636 | ||
Phospholipids regulate localization and activity of mDia1 formin | Q42824761 | ||
Actin filament bundling and different nucleating effects of mouse Diaphanous-related formin FH2 domains on actin/ADF and actin/cofilin complexes | Q42876929 | ||
The formin INF2 regulates basolateral-to-apical transcytosis and lumen formation in association with Cdc42 and MAL2. | Q43056651 | ||
The regulation of mDia1 by autoinhibition and its release by Rho*GTP. | Q43192533 | ||
Formin mDia1 senses and generates mechanical forces on actin filaments | Q44189807 | ||
The mDial formin is required for neutrophil polarization, migration, and activation of the LARG/RhoA/ROCK signaling axis during chemotaxis | Q44312178 | ||
F- and G-actin homeostasis regulates mechanosensitive actin nucleation by formins | Q44627297 | ||
Actin polymerization-driven molecular movement of mDia1 in living cells | Q44814909 | ||
Formin is a processive motor that requires profilin to accelerate actin assembly and associated ATP hydrolysis | Q45126402 | ||
P275 | copyright license | Creative Commons Attribution-NonCommercial 3.0 Unported | Q18810331 |
P921 | main subject | enzyme | Q8047 |
fetal proteins | Q5445910 | ||
peptide | Q172847 | ||
transport protein | Q2111029 | ||
nuclear protein | Q16860021 | ||
cytoskeletal proteins | Q66563066 | ||
macromolecular substance | Q75174158 | ||
P304 | page(s) | e29513 | |
P577 | publication date | 2014-06-10 | |
P1433 | published in | Small GTPases (journal) | Q15709529 |
P1476 | title | Formins as effector proteins of Rho GTPases | |
P478 | volume | 5 |
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Q37386996 | Constitutive activation of DIA1 (DIAPH1) via C-terminal truncation causes human sensorineural hearing loss |
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Q95595117 | FMNL1 mediates nasopharyngeal carcinoma cell aggressiveness by epigenetically upregulating MTA1 |
Q38603003 | FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42. |
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Q40036057 | First Evidence of DAAM1 Localization During the Post-Natal Development of Rat Testis and in Mammalian Sperm. |
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Q30811909 | Formin-mediated actin polymerization at cell-cell junctions stabilizes E-cadherin and maintains monolayer integrity during wound repair. |
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Q39038218 | Glycation & the RAGE axis: targeting signal transduction through DIAPH1. |
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